hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbj/mbj00169/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00387  ( 590 res)   mbj00169

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic     40.6    3.4e-12   1
TyrKc    Tyrosine kinase, catalytic domain             -115.6    0.00056   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1     166   516 ..     1   280 []  -115.6  0.00056
S_TKc      1/1     166   520 ..     1   231 []    40.6  3.4e-12

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 166 to 516: score -115.6, E = 0.00056
                   *->ltlgkkLGeGaFGeVykGtlk..........................
                         g+ +G G+   Vy++t+ + +++ ++ ++ +  +++++   ++ 
   mFLJ00387   166    YLIGQAIGKGCNAAVYEATMPtlpqhlekakhlgligkgpdvvlkga 212  

                   ..........ieVAVKtLkeda....................keeFlrEa
                   ++++ +++++ + A+K++ + + +++++   ++ +++  + ++ ++  E 
   mFLJ00387   213 dgeqapgtptFPFAIKMMWNISagssseailskmsqelvpasRVALDGEY 262  

                   kiM.........kklGgkHpNiVkLlGvcteegrrFmevePlmivmEyme
                      + +++++++k+l   HpNi++ + + t++        Pl+       
   mFLJ00387   263 GAVtyrrsrdgpKQL-APHPNIIRVFRAFTSS-------VPLL------- 297  

                   gGdLldyLrknrpk...............................lslsd
                    G+L dy     p+  +++ +++++     ++ + + ++  ++++ s + 
   mFLJ00387   298 PGALADYPDMLPPHyypeglghgrtlflvmknypctlrqyleeqtPSSRL 347  

                   LlsfAlQIAkGMeYLesknfvHRDLAARNcLvgenk.....vvKIsDFGL
                      + lQ  +G ++L ++++ HRDL   N+Lv  + ++ +  v IsDFG 
   mFLJ00387   348 ATMMTLQLLEGVDHLVQQGIAHRDLKSDNILVEWDSdgcpwLV-ISDFGC 396  

                   sRdlyddDkkG....eskdyYrkkggkggktllPirWmAPEsl......k
                   + +  +    G + + +++        gg++ l    mAPE+ + ++++ 
   mFLJ00387   397 CLADQHV---GlrlpFNSSSVER----GGNGSL----MAPEVStahsgpS 435  

                   dgkFtskSDVWSFGVlLWEiftlGeqPYpgeiqqfmsneevleylkkGyR
                     +  sk D W+ G   +Eif l  + Y        s+    +  ++   
   mFLJ00387   436 AVIDYSKADTWAVGAIAYEIFGLANPFYGQ-----GSAHLESRSYQEAQL 480  

                   lpkPendlpiSsvtCPdelYdlMlqCWaedPedRPtFselverl<-*
                   +++P++         P+e  +l ++  ++++++RP+ +     l   
   mFLJ00387   481 PEIPKS--------VPPEARRLVRSLLQREASKRPSARLAANVL    516  

S_TKc: domain 1 of 1, from 166 to 520: score 40.6, E = 3.4e-12
                   *->YellkklGkGaFGkVylardkk.........................
                      Y +++ +GkG  + Vy a+    +++ ++ ++ +  +++++   ++ 
   mFLJ00387   166    YLIGQAIGKGCNAAVYEATMPTlpqhlekakhlgligkgpdvvlkga 212  

                   ........tgrlvAiKvik...............................
                   ++++ +++    +AiK++ + + +++++   ++ +++  + ++   +++ 
   mFLJ00387   213 dgeqapgtPTFPFAIKMMWnisagssseailskmsqelvpasrvaldgey 262  

                   ..erilrEikiLkk..dHPNIVkLydvfed....................
                   +  + +r ++  k+   HPNI++ + +f ++ +  ++   + ++  +++ 
   mFLJ00387   263 gaVTYRRSRDGPKQlaPHPNIIRVFRAFTSsvpllpgaladypdmlpphy 312  

                   ........dklylVmEyceGdlGdLfdllkkrgrrglrkvlsE.earfyf
                    +++ +++  l+lVm   +    +L+++l+++ +       s + a  ++
   mFLJ00387   313 ypeglghgRTLFLVMKNYPC---TLRQYLEEQTP-------SSrLATMMT 352  

                   rQilsaLeYLHsqgIiHRDLKPeNiLLds......hvKlaDFGlArql..
                    Q+l+++++L +qgI HRDLK +NiL+  ++++ + + ++DFG +   ++
   mFLJ00387   353 LQLLEGVDHLVQQGIAHRDLKSDNILVEWdsdgcpWLVISDFGCCLADqh 402  

                   ...........ttfvGTpeYmAPEvl..........gYgkpavDiWSlGc
                    + + + ++++    G    mAPEv + +++++    Y+  ++D W++G 
   mFLJ00387   403 vglrlpfnsssVERGGNGSLMAPEVStahsgpsaviDYS--KADTWAVGA 450  

                   ilyElltGkpPFp......qldlifkkig........SpeakdLikklLv
                   i yE +    PF+++++ + + + ++    ++ +++ +pea+ L++ lL+
   mFLJ00387   451 IAYEIFGLANPFYgqgsahLESRSYQEAQlpeipksvPPEARRLVRSLLQ 500  

                   kdPekRlta.eaLedeldikaHPff<-*
                   ++ +kR++a+ a +      +H  +   
   mFLJ00387   501 REASKRPSArLAAN-----VLHLSL    520  

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