hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbj/mbj00169/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00387  ( 590 res)   mbj00169

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                        65.0    1.6e-15   1
Pkinase_Tyr Protein tyrosine kinase                     -74.1    2.9e-07   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase_Tyr   1/1     166   516 ..     1   272 []   -74.1  2.9e-07
Pkinase       1/1     166   521 ..     1   287 []    65.0  1.6e-15

Alignments of top-scoring domains:
Pkinase_Tyr: domain 1 of 1, from 166 to 516: score -74.1, E = 2.9e-07
                   *->lklgkkLGeGaFGeVykGtlkg.........................
                        +g+ +G+G+   Vy++t    +++ ++ ++ +  +++++   ++ 
   mFLJ00387   166    YLIGQAIGKGCNAAVYEATMPTlpqhlekakhlgligkgpdvvlkga 212  

                   ....sgegtkikVAVKtL.ke.igasseeieredFlrEAsiMkklGdHpN
                   ++++ ++ ++ + A+K++ + + g+sse+i + ++ +E+   ++      
   mFLJ00387   213 dgeqAPGTPTFPFAIKMMwNIsAGSSSEAI-LSKMSQELVPASRV----- 256  

                   iVrL...lGvct......................................
                      L++++G++t +++++++++  ++++  +  +  +++ +  ++   + 
   mFLJ00387   257 --ALdgeYGAVTyrrsrdgpkqlaphpniirvfraftssvpllpgalady 304  

                   ..............kegePggpglyiVtEymegGdLldfLrkhregrpLt
                   ++  +++  +++ ++ g+     l++V+   ++  L+ +L ++     ++
   mFLJ00387   305 pdmlpphyypeglgH-GRT----LFLVMKNYPC-TLRQYLEEQ----TPS 344  

                   lkdLlsfalQiAkGMeYLesknfvHRDLAARNcLVs...enl.vVKIsDF
                         + lQ  +G ++L ++++ HRDL   N+LV  ++++ +   IsDF
   mFLJ00387   345 SRLATMMTLQLLEGVDHLVQQGIAHRDLKSDNILVEwdsDGCpWLVISDF 394  

                   GLaRdiynddyYvrkkgggklPv...........kWmAPEslkygk....
                   G + +         ++ g +lP ++++ ++++++  mAPE+     +++ 
   mFLJ00387   395 GCCLA--------DQHVGLRLPFnsssverggngSLMAPEVSTAHSgpsa 436  

                   ..FtskSDVWSFGVlLWEiftlGeqPFYpgmsneevlellyedGyRLprP
                       sk D W+ G   +Eif l   P ++g   + +  + y++ +  ++P
   mFLJ00387   437 viDYSKADTWAVGAIAYEIFGLA-NP-FYGQGSAHLESRSYQEAQLPEIP 484  

                   enCPdelYdlMlqCWaedPedRPtFselverL<-*
                   +  P+e  +l ++  ++++++RP+ +   + L   
   mFLJ00387   485 KSVPPEARRLVRSLLQREASKRPSARLAANVL    516  

Pkinase: domain 1 of 1, from 166 to 521: score 65.0, E = 1.6e-15
                   *->yelleklGsGsfGtVykakhkgtgk......................
                      y +++ +G+G  + Vy+a+    +++ ++ ++ +  +++++   ++ 
   mFLJ00387   166    YLIGQAIGKGCNAAVYEATMPTLPQhlekakhlgligkgpdvvlkga 212  

                   ...........iVAvKiikkrkekskkdktarrr...............s
                   ++++ +++++  +A+K ++  ++ s+   +a++++ +++  + ++   ++
   mFLJ00387   213 dgeqapgtptfPFAIKMMWNISAGSSS--EAILSkmsqelvpasrvaldG 260  

                   EiqilkrLs..........HpNIvrlidvfed..................
                   E       ++++++++  +HpNI+r +++f+++ +  ++   + ++  ++
   mFLJ00387   261 EYGAVTYRRsrdgpkqlapHPNIIRVFRAFTSsvpllpgaladypdmlpp 310  

                   .........kdhlylVlEycegGLrlldLfdylsetrrkgpllfsedeak
                   +  +++ ++++ l lV+   ++      L  yl     + +   s + a 
   mFLJ00387   311 hyypeglghGRTLFLVMKNYPC-----TLRQYLE----EQTP--SSRLAT 349  

                   kialQilrgleYLHsngiiHRDLKPeNILldengvvdaflKiaDFGlAkk
                   ++ lQ+l+g+++L ++gi HRDLK++NIL+  + + ++ l i+DFG++ +
   mFLJ00387   350 MMTLQLLEGVDHLVQQGIAHRDLKSDNILVEWDSDGCPWLVISDFGCC-L 398  

                   ls......t.sss.lttfvGTpwYmAPEvll.....ggngygtkvDvWSl
                   ++++ + +++ +s+   + G    mAPEv   ++++++  + +k+D W++
   mFLJ00387   399 ADqhvglrLpFNSsSVERGGNGSLMAPEVSTahsgpSAVIDYSKADTWAV 448  

                   GvilyelltGkpPFsgevqds.ldqlqlirkilgpplefdspewdsisrs
                   G i ye +    PF+g+   +++    + ++  + p   ++p++ +    
   mFLJ00387   449 GAIAYEIFGLANPFYGQ---GsAHLESRSYQEAQLP---EIPKSVP---- 488  

                   efrrlpnlseeakdLikkcLnkDPskRlt...aeeilqHPwf<-*
                            +ea+ L++++L++  skR++ + a+ +l+   +   
   mFLJ00387   489 ---------PEARRLVRSLLQREASKRPSarlAANVLHLSLW    521  

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