hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/msh/msh02173/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00369  ( 939 res)   msh02173

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   226.0    3.3e-63   1
PH       Pleckstrin homology domain.                     32.5    5.9e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RhoGEF     1/1     438   622 ..     1   211 []   226.0  3.3e-63
PH         1/1     666   780 ..     1    82 []    32.5  5.9e-05

Alignments of top-scoring domains:
RhoGEF: domain 1 of 1, from 438 to 622: score 226.0, E = 3.3e-63
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v+ ELl+TE+++Vr+L++l + f++p+ + +      +++ de++ +
   mFLJ00369   438    VISELLVTEAAHVRMLRVLHDLFYQPMADGG------FFPLDELQNI 478  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   F+  ++e++e+H+ FLd+L++r++e+          +++ie +g+++ + 
   mFLJ00369   479 FP-SLDELIEVHSLFLDRLMKRRQES----------GYLIEEIGDVLLAR 517  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   F++  +++ f ki s++cs+++ ale lk   k++k p+F +f++e+es+
   mFLJ00369   518 FDGA-EGSWFQKISSRFCSRQSFALEQLKA--KQRKEPRFCAFVQEAESR 564  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLkk
                   p+cr     rl+L++++++ +QRltkYpLLL+ + ++t+ ++ +r +++ 
   mFLJ00369   565 PRCR-----RLQLKDMIPTEMQRLTKYPLLLQSIGQNTE-ESTERGKVEL 608  

                   AleaikelasqvNe<-*
                   A e+++e++++vN+   
   mFLJ00369   609 AAECCREILHHVNQ    622  

PH: domain 1 of 1, from 666 to 780: score 32.5, E = 5.9e-05
                   *->vikeGwLlkks.k.swkkryfvLfngvLlyyksk.............
                      +++eG L+++ +k++  ++++ L ++ Ll+ +  +++   ++++++ 
   mFLJ00369   666    LVHEGPLTWRVtKdKAIEVHVLLLDDLLLLLQRQderlllkshsrtl 712  

                   ........kpkgsipLsgc.svre.p....cFeivt.dr...tlllqAes
                   ++++++++ +++++ L+++ + ++ ++++    i+t d++ + ++l A +
   mFLJ00369   713 tptpdgktMLRPVLRLTSAmTREVaTdhkaFYVIFTwDQeaqIYELVAQT 762  

                   eeereeWvealqsaiaka<-*
                   ++er+ W + + + + ++   
   mFLJ00369   763 SSERKNWCNLITETAGSL    780  

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