hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg10993/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00298  ( 577 res)   mbg10993

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   210.0    2.1e-58   1
SH3      Src homology 3 domains                          68.5    8.4e-16   1
PH       Pleckstrin homology domain.                     47.8    1.4e-09   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SH3        1/1      75   130 ..     1    58 []    68.5  8.4e-16
RhoGEF     1/1     169   348 ..     1   211 []   210.0  2.1e-58
PH         1/1     381   488 ..     1    82 []    47.8  1.4e-09

Alignments of top-scoring domains:
SH3: domain 1 of 1, from 75 to 130: score 68.5, E = 8.4e-16
                   *->eyvvAlYDyeaqnedELsFkkGDiitvleksddgWweGelnrtGkeG
                      + + Al+D+   +++EL Fk+GD+i+vle s+ +Ww+G++    ke 
   mFLJ00298    75    VCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRNE--DKEA 119  

                   lfPsnYVeeie<-*
                   +fP+++V++     
   mFLJ00298   120 WFPASFVRLRV    130  

RhoGEF: domain 1 of 1, from 169 to 348: score 210.0, E = 2.1e-58
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v++E++ TEr Y+++Lk + e+++++++k        +++  ++ t+
   mFLJ00298   169    VIQEIMNTERVYIKHLKDICEGYIRQCRKHTG-----MFTVAQLATI 210  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   Fg Nie+iy+f+r+FL++Le+  ++ +              ++  +ig++
   mFLJ00298   211 FG-NIEDIYKFQRKFLKDLEKQYNKEE--------------PHLSEIGSC 245  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   Fl++   +e f iYseYc+nhp a   l+ Lm   k +++++f++ + + 
   mFLJ00298   246 FLEH---QEGFAIYSEYCNNHPGACVELSNLM---KHSKYRHFFEACRLL 289  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLkk
                   ++++     +  L+ +L++PvQ ++kYpL L ellk+t+ +h d++++k 
   mFLJ00298   290 QQMI-----DIALDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYNNIKA 334  

                   AleaikelasqvNe<-*
                   A+ea+k++a  +Ne   
   mFLJ00298   335 AYEAMKNVACLINE    348  

PH: domain 1 of 1, from 381 to 488: score 47.8, E = 1.4e-09
                   *->vikeGwLlkks.k.swkkryfvLfngvLlyyksk.......kpkgsi
                      +i++G L+k ++ ++ ++r f+Lf+++L+ +k++  +++   +kg++
   mFLJ00298   381    LIHSGELTKITrQgKSQQRIFFLFDHQLVSCKKDllrrdmlYYKGRM 427  

                   pLsgcsvre.p.............cFeivt.dr..tlllqAeseeereeW
                   +++++++++ +++++++ + + +++F++v++  ++++l++A+ +e++ +W
   mFLJ00298   428 DMDEVELVDvEdgrdkdwslslrnAFKLVSkATdeVHLFCARKQEDKARW 477  

                   vealqsaiaka<-*
                   ++a  +  ++    
   mFLJ00298   478 LQAYADERRRV    488  

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