hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mbg/mbg10993/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00298  ( 577 res)   mbg10993

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   RhoGEF domain                                  156.8    3.7e-43   1
SH3_1    SH3 domain                                      52.0    1.3e-11   1
PH       PH domain                                       47.1    3.8e-10   1
SH3_2    Variant SH3 domain                              29.3    9.1e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SH3_1      1/1      75   129 ..     1    58 []    52.0  1.3e-11
SH3_2      1/1      76   129 ..     1    69 []    29.3  9.1e-05
RhoGEF     1/1     169   348 ..     1   207 []   156.8  3.7e-43
PH         1/1     381   486 ..     1    92 []    47.1  3.8e-10

Alignments of top-scoring domains:
SH3_1: domain 1 of 1, from 75 to 129: score 52.0, E = 1.3e-11
                   *->kkvvALYDYearesdELsFkkGDvitvleksddgWWkgrlkgtgGke
                        + AL D + ++++EL Fk GDvi+vle s+ +WW gr+    +ke
   mFLJ00298    75    VCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRNE---DKE 118  

                   GliPsNYVepv<-*
                    ++P+++V++    
   mFLJ00298   119 AWFPASFVRLR    129  

SH3_2: domain 1 of 1, from 76 to 129: score 29.3, E = 9.1e-05
                   *->ygraiedyvaAtdknenleeeeLslkkGdvvkvidvggskdddgwwl
                       + a+ d+v   d +e      L +k+Gdv+ v+    + ++ +ww+
   mFLJ00298    76    CAEALWDHVT-MDDQE------LGFKAGDVIQVL----EASNKDWWW 111  

                   geslggGrrrRGlvPssaveel<-*
                   g++  ++++   ++P+s+v+     
   mFLJ00298   112 GRN-EDKEA---WFPASFVRLR    129  

RhoGEF: domain 1 of 1, from 169 to 348: score 156.8, E = 3.7e-43
                   *->vlkElleTEkkYvrdLeildnvymkpLreaaisskpvltpddietiF
                      v+ E++ TE+ Y+++L ++  +y ++ r+        +t  ++ tiF
   mFLJ00298   169    VIQEIMNTERVYIKHLKDICEGYIRQCRKHT----GMFTVAQLATIF 211  

                   sNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlFlklk
                   +Niediy+f+r FLk  Le+    +          ep+ + +G++Fl++ 
   mFLJ00298   212 GNIEDIYKFQRKFLK-DLEKQYNKE----------EPHLSEIGSCFLEH- 249  

                   epflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
                    + +++Y eYc+n+p A   l+ l   ++ + F+e +  +++  +     
   mFLJ00298   250 QEGFAIYSEYCNNHPGACVELSNLMKHSKYRHFFEACRLLQQMID----- 294  

                   davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdredLkkaldl
                         L+ +Ll Pvq i++YpL L eLLk+t    ++ d+++ k+a+++
   mFLJ00298   295 ----IALDGFLLTPVQKICKYPLQLAELLKYTTQ--EHGDYNNIKAAYEA 338  

                   lqdlaksiNe<-*
                   ++++a+ iNe   
   mFLJ00298   339 MKNVACLINE    348  

PH: domain 1 of 1, from 381 to 486: score 47.1, E = 3.8e-10
                   *->vikeGwLlkkggkkswkkRyfvLfndvLlyykdkk.....kkpkgsi
                      +i++G+L+k ++ ++ ++R f+Lf+++L+ +k++  +++   +kg +
   mFLJ00298   381    LIHSGELTKITRQGKSQQRIFFLFDHQLVSCKKDLlrrdmLYYKGRM 427  

                   pLsgiqvekvpdn.......krkncFeirt.dr.etlllqaeseeerkeW
                   +++++++++v+d+++++ +   +n+F+++++  +e++l++a  +e++ +W
   mFLJ00298   428 DMDEVELVDVEDGrdkdwslSLRNAFKLVSkATdEVHLFCARKQEDKARW 477  

                   vkaiqsair<-*
                   ++a  ++ r   
   mFLJ00298   478 LQAYADERR    486  

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