hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mfj/mfj26301/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00285  ( 838 res)   mfj26301

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PKD      PKD domain                                     580.5   1.1e-170   9

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
PKD        1/9      46   144 ..     1    92 []    62.3    1e-14
PKD        2/9     153   230 ..     1    92 []    88.7  1.1e-22
PKD        3/9     241   313 ..     1    92 []    64.3  2.6e-15
PKD        4/9     321   398 ..     1    92 []    54.8  1.9e-12
PKD        5/9     407   484 ..     1    92 []    76.3  6.5e-19
PKD        6/9     493   566 ..     1    92 []    79.0  9.9e-20
PKD        7/9     575   650 ..     1    92 []    78.3  1.6e-19
PKD        8/9     659   739 ..     1    92 []    49.2  9.2e-11
PKD        9/9     748   823 ..     1    92 []    71.0  2.5e-17

Alignments of top-scoring domains:
PKD: domain 1 of 9, from 46 to 144: score 62.3, E = 1e-14
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGD....
                      vsa+     p+v+++++t  +t+ + ++++ +  v+++W+FGD+++ 
   mFLJ00285    46    VSAV-----PTVLPPNATLALTGGV-LVDS-AVEVAFLWNFGDgeqv 85   

                   ...............ggstgltstepnvtHtYskgsVtpGtYtVtLtvsN
                    ++ +++ +++ + ++ +  +++ e n tH+Y++    pG+Y++t+ vsN
   mFLJ00285    86 lrqfkppydesfqvpDPTVAQVLVEHNTTHIYTT----PGEYNLTVLVSN 131  

                   gvgsasattttvtV<-*
                    + + +++ +tv V   
   mFLJ00285   132 TYENLTQQ-VTVSV    144  

PKD: domain 2 of 9, from 153 to 230: score 88.7, E = 1.1e-22
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGDggst
                      +  s     ++v+++g+++tF+      p+  ++v y+WdFGD gs+
   mFLJ00285   153    IGMS-----SNVLVAGQPITFSPYP--LPS-TDGVLYTWDFGD-GSP 190  

                   gltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                   +l+ ++p  +HtYs     +GtY +tL v+N v+s++a+ + + V   
   mFLJ00285   191 VLIQSQPVLNHTYSM----TGTYRITLEVNNTVSSVTAH-ADIRV    230  

PKD: domain 3 of 9, from 241 to 313: score 64.3, E = 2.6e-15
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGDggst
                      +s+s        v++g++ +++as+   ++ g++++++ d GD  +t
   mFLJ00285   241    LSPS--------VEQGAPMVVSASV---ES-GDNITWTFDMGD--GT 273  

                   gltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                   + t+ e +v H+Y++    + ++tVt+ + N +g+ s++ ++v V   
   mFLJ00285   274 VFTGPEATVQHVYLR----AQNFTVTVEAANPAGHLSQS-LHVQV    313  

PKD: domain 4 of 9, from 321 to 398: score 54.8, E = 1.9e-12
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsys..WdFGDgg
                      + +s      + ++++ ++++ a++    + g+pv+y+ +W+FGDg+
   mFLJ00285   321    IEPS------TCIPTQPSAQLMAHV----T-GDPVHYLfdWTFGDGS 356  

                   stgltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                   s++++++ p+vtH +++     G +++ L+ s++v+ a+   t+++V   
   mFLJ00285   357 SNVTVHGHPSVTHNFTR----SGIFPLALVLSSHVNKAHYF-TSICV    398  

PKD: domain 5 of 9, from 407 to 484: score 76.3, E = 6.5e-19
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGDggst
                      ++++     +++v+lg ++++ a s   ++ + p+ y+WdFG +++t
   mFLJ00285   407    LQPE-----RQFVKLGDEARLVAYS---WP-PFPYRYTWDFGTEDTT 444  

                   gltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                    + +++++v  +Y++    pG+Y V +tvsN+ +s++ + ++v+V   
   mFLJ00285   445 HTQTGGSEVKFIYRE----PGSYLVIVTVSNNISSTNDS-AFVEV    484  

PKD: domain 6 of 9, from 493 to 566: score 79.0, E = 9.9e-20
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGDggst
                      +  +    g+ v++l++++ ++a      + gsp++y+W  GD    
   mFLJ00285   493    IRIN----GSHVLELQQPYLLSAMG----S-GSPATYLWELGD---- 526  

                   gltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                   g+ s +p+vtH+Ys+    +G++tV++  +N+v+++ a+ +++tV   
   mFLJ00285   527 GSQSEGPEVTHIYSS----TGDFTVRVSGWNEVSRSEAQ-LNITV    566  

PKD: domain 7 of 9, from 575 to 650: score 78.3, E = 1.6e-19
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGDggst
                      ++as     ++vv+l+ +V+F+ ++   +  gs+v+ysW  +D   +
   mFLJ00285   575    INAS-----RTVVPLNGSVSFSTLL---EV-GSDVHYSWVLCD--RC 610  

                   gltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                   + + ++p++++t+++     Gt+++ +t++N+vgsa  + ++++V   
   mFLJ00285   611 TPIPGGPTISYTFRS----VGTFNIIVTAENEVGSAQDS-IFIYV    650  

PKD: domain 8 of 9, from 659 to 739: score 49.2, E = 9.2e-11
                   *->vsasaveegpsvvalgetVtFtassSydpdpgspvsysWdFGD.ggs
                      v+++   + +  ++++ t +++a++    d g+++sysW+   +g+ 
   mFLJ00285   659    VAGG---DNGCCFPTNYTLQLQAAV---RD-GTNISYSWTAQQeGSL 698  

                   tgltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                    +l ++++ ++ t +k    + tY V L+++N+ gsa+a+ +t+     
   mFLJ00285   699 ITLFGSGKCFSLTALK----ASTYYVHLRATNMLGSAAAN-RTIDF    739  

PKD: domain 9 of 9, from 748 to 823: score 71.0, E = 2.5e-17
                   *->vsasaveegpsvvalgetVtFtassSydpdp.gspvsysWdFGDggs
                      +sas     p+++a++ + t+ a +     ++gs+v y+W+     +
   mFLJ00285   748    LSAS-----PNPAAVNMSLTLCAEL-----AgGSGVVYTWYLEE--G 782  

                   tgltstepnvtHtYskgsVtpGtYtVtLtvsNgvgsasattttvtV<-*
                    ++ ++ p+ tHt+ +    pG + V++t++N  gs++at ++v +   
   mFLJ00285   783 LSWKTSMPSTTHTFAT----PGLHLVRVTAENQLGSVNAT-VEVAI    823  

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