hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mpf/mpf00869/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00274  ( 1530 res)   mpf00869

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
PH       PH domain                                      100.9    2.6e-26   2
FYVE     FYVE zinc finger                                56.8    4.7e-13   1
RhoGEF   RhoGEF domain                                   30.5    5.2e-07   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RhoGEF     1/1     962  1150 ..     1   207 []    30.5  5.2e-07
PH         1/2    1181  1274 ..     1    92 []    65.9  8.7e-16
FYVE       1/1    1304  1369 ..     1    77 []    56.8  4.7e-13
PH         2/2    1432  1529 ..     1    92 []    35.0  1.7e-06

Alignments of top-scoring domains:
RhoGEF: domain 1 of 1, from 962 to 1150: score 30.5, E = 5.2e-07
                   *->vlkElleTEkkYvrdLeildnvy....mkpLreaaisskpvltpddi
                      ++ Ell +Ek+Yv+ L +l+ ++++  ++ L + +   + +l ++++
   mFLJ00274   962    IAQELLSSEKAYVQMLQHLSLDFhgavLRALENVEQEGREPLAQEEL 1008 

                   etiFsNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlF
                         ++ i ++h+ +L  sLe+r+ +            ++++ ++d+F
   mFLJ00274  1009 RQGLRELPAICDLHQGILE-SLEQRLGDC----------GEGQPQVADIF 1047 

                   lklkepflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassnt
                   l++ e ++++ ++ + ++++   ll+    +  +p +a  + e e+ss+ 
   mFLJ00274  1048 LAR-EQEFEHHAAHILQFDRYLGLLAE--SCLLSPRLATTVREFEQSSQG 1094 

                   gAkddavkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdredLkk
                   g        +  + +l  vqR++ Y+ LL ++L    +  d+ ++ + + 
   mFLJ00274  1095 G------GQSMKHRMLRVVQRLFQYQVLLTDYLNNLCP--DSAEYDNTQS 1136 

                   aldllqdlaksiNe<-*
                   al l+  +  + Ne   
   mFLJ00274  1137 ALTLISKVTDRANE    1150 

PH: domain 1 of 2, from 1181 to 1274: score 65.9, E = 8.7e-16
                   *->vikeGwLlkkggkkswkkRyfvLfndvLlyykdkk...kkpkgsipL
                        keG L++   +ks+++R+++L nd+Lly  + k++++++k s+p+
   mFLJ00274  1181    FLKEGTLMRVR-GKSRHPRHLFLMNDTLLYTHPQKdgkYRLKSSLPV 1226 

                   sgiqvekvpdnkrkncFeirt.dretlllqaeseeerkeWvkaiqsair<
                    +++v +++  k +++++i t++  +l+l+a+s+ er+eW  ++++a+  
   mFLJ00274  1227 ANMKVSRPVMDKVPYALKIETpES-CLTLSASSCAERDEWHYCLSRALP  1274 

                   -*
                     
   mFLJ00274     -    -    

FYVE: domain 1 of 1, from 1304 to 1369: score 56.8, E = 4.7e-13
                   *->phWvpDeevsnCmrCgkpFtkltkRrHHCRaCGrifCgsCssktvll
                      p+ vp   + +Cm+Cg  F+ lt+RrHHC aCG+i+C++Cs+++ +l
   mFLJ00274  1304    PTLVPVTHAMMCMNCGCDFS-LTVRRHHCHACGKIVCRNCSRNKYPL 1349 

                   pylgiaallkndviekpvRVCdsCydrlnk<-*
                   + l          +++ + VCd C+  l+    
   mFLJ00274  1350 KCL----------KNRMAKVCDGCFRELKL    1369 

PH: domain 2 of 2, from 1432 to 1529: score 35.0, E = 1.7e-06
                   *->vikeGwLlkkg.gkkswkkRyfvLfndvLlyykdkk.kkpkgsipLs
                        ++G+L++  +gk++wkk ++v++++vL+ y  + +k    sipL 
   mFLJ00274  1432    SAISGYLSRCKsGKRRWKKLWLVIKGKVLYTYLASEdKVAMESIPLL 1478 

                   giqvekvpdn...krkncFeirt.dretlllqaeseeerkeWvkaiqsai
                   g ++ + ++ ++++   +F + ++    + ++ae++ ++++W++a ++a+
   mFLJ00274  1479 GFTIAPEKEEgssEVGPVFHLYHkKTLFYSFKAEDSNSAQRWMEAMEDAS 1528 

                   r<-*
                       
   mFLJ00274  1529 V    1529 

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