hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mtj/mtj02051/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00113  ( 442 res)   mtj02051

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
S_TKc    Serine/Threonine protein kinases, catalytic    107.0    2.1e-27   1
TyrKc    Tyrosine kinase, catalytic domain              -97.9    4.4e-05   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
TyrKc      1/1      72   335 ..     1   280 []   -97.9  4.4e-05
S_TKc      1/1      42   339 ..     1   231 []   107.0  2.1e-27

Alignments of top-scoring domains:
TyrKc: domain 1 of 1, from 72 to 335: score -97.9, E = 4.4e-05
                   *->ltlgkkLGeGaFGeVykGtlkieVAVKtLkeda..keeFlrEakiMk
                      l+ +    +G+ G+               +e+ ++k+ ++ E ++++
   mFLJ00113    72    LKILTLEERGEQGI-------------ESQEERqgKMLLHTEYSLLS 105  

                   klGgkHp.NiVkLlGvcteegrrFmevePlmivmEymegGdLldyLrknr
                    l  + ++ +V  +G            +  +  +E  e G   +  +k+ 
   mFLJ00113   106 LL--HTQdGVVHHHGLFQ---------DRTCEAVEDTESGRMVKKMKKRI 144  

                   pk.............................lslsdLlsfAlQIAkGMeY
                       +    ++ ++++ +  + ++   ++++ls ++ + + +++ +  e 
   mFLJ00113   145 CLvldclcahdfsdktadlinlqhyvikekrLSERETVVIFYDVVRVVEA 194  

                   LesknfvHRDLAARNcLvgenk.vvKIsDFGLsRdlyddDkkGeskdyYr
                   L++kn+vHRDL   N  ++++ +++ I+ F L + l ++      +d  +
   mFLJ00113   195 LHQKNIVHRDLKLGNMVLNKRThRITITNFCLGKHLVSE------GDLLK 238  

                   kkggkggktllPirWmAPEslkdgkFtsk.SDVWSFGVlLWEiftlGeqP
                    +   g+         +P +l  + +  k+SD W+ GV+L+ ++ +G+ P
   mFLJ00113   239 DQR--GSP-----AYISPDVLSGRPYRGKpSDMWALGVVLFTML-YGQFP 280  

                   YpgeiqqfmsneevleylkkGyRlpkPendlpiSsvtCPdelYdlMlqCW
                    ++       ++e+++++k+ ++  + +        + ++    l+++  
   mFLJ00113   281 FYD-----SIPQELFRKIKAAEYTIPEDG-------RVSENTVCLIRKLL 318  

                   aedPedRPtFselverl<-*
                     dP +R   +++ e l   
   mFLJ00113   319 VLDPQQRLAAADVLEAL    335  

S_TKc: domain 1 of 1, from 42 to 339: score 107.0, E = 2.1e-27
                   *->YellkklGkGaFGkVylardkk..tgrlvAiKvik............
                      + l+  lG     +  ++  +k++t+  + +K++  +++++++ +++
   mFLJ00113    42    FVLGPRLGNSPVPSIVQCLARKdgTDDFYQLKILTleergeqgiesq 88   

                   ......erilrEikiLkk..dHPNIVkLydvfed................
                   ++++++  +  E ++L+  +  + +V+ ++ f+d++ +  +++++++  +
   mFLJ00113    89 eerqgkMLLHTEYSLLSLlhTQDGVVHHHGLFQDrtceavedtesgrmvk 138  

                   ...dklylVmEyc........eGdlGdLfdllkkrgrrglrkvlsE.ear
                   + +++++lV++++  ++ +++  dl +L ++  k +r      lsE+e+ 
   mFLJ00113   139 kmkKRICLVLDCLcahdfsdkTADLINLQHYVIKEKR------LSErETV 182  

                   fyfrQilsaLeYLHsqgIiHRDLKPeNiLLds...hvKlaDFGlArql..
                    +f+ +++ +e LH+++I+HRDLK  N  L+++++++ ++ F l ++l +
   mFLJ00113   183 VIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKrthRITITNFCLGKHLvs 232  

                   .....ttfvGTpeYmAPEvl...gYgkpavDiWSlGcilyElltGkpPFp
                   +++  + + G+p Y++P vl++++Y ++++D+W+lG++l+ +l+G+ PF+
   mFLJ00113   233 egdllKDQRGSPAYISPDVLsgrPYRGKPSDMWALGVVLFTMLYGQFPFY 282  

                   ..qldlifkkig............SpeakdLikklLvkdPekRlta.eaL
                   ++ ++++f+ki+  +++ +++++ S+    Li+klLv dP++Rl a ++L
   mFLJ00113   283 dsIPQELFRKIKaaeytipedgrvSENTVCLIRKLLVLDPQQRLAAaDVL 332  

                   edeldikaHPff<-*
                   e     ++   +   
   mFLJ00113   333 E-----ALSAII    339  

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