hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/Pfam
Sequence file:            /cdna4/rodent/full/goal/mtj/mtj02051/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00113  ( 442 res)   mtj02051

Scores for sequence family classification (score includes all domains):
Model       Description                                 Score    E-value  N 
--------    -----------                                 -----    ------- ---
Pkinase     Protein kinase domain                       122.2    9.6e-33   1
Pkinase_Tyr Protein tyrosine kinase                    -121.8    0.00027   1

Parsed for domains:
Model       Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------    ------- ----- -----    ----- -----      -----  -------
Pkinase       1/1      42   335 ..     1   287 []   122.2  9.6e-33
Pkinase_Tyr   1/1      42   335 ..     1   272 []  -121.8  0.00027

Alignments of top-scoring domains:
Pkinase: domain 1 of 1, from 42 to 335: score 122.2, E = 9.6e-33
                   *->yelleklGsGsfGtV.....ykakhkgtgkiVAvKiikkrkekskkd
                      ++l+ +lG    + V++  +++a++ gt + + +Ki+ ++++ ++  
   mFLJ00113    42    FVLGPRLGN---SPVpsivqCLARKDGTDDFYQLKILTLEERGEQGI 85   

                   ktarrr.......sEiqilkrL.sHpNIvrlidvfed.............
                   ++   r+++   + E ++l  L+  + +v  ++ f+d++ +  +++++++
   mFLJ00113    86 ESQEERqgkmllhTEYSLLSLLhTQDGVVHHHGLFQDrtceavedtesgr 135  

                   .....kdhlylVlE.ycegGL.r....lldLfdylsetrrkgpllfsede
                     ++ k++++lVl+ +c ++ ++++ +l+ L +y+    ++++l  se+e
   mFLJ00113   136 mvkkmKKRICLVLDcLCAHDFsDktadLINLQHYVI---KEKRL--SERE 180  

                   akkialQilrgleYLHsngiiHRDLKPeNILldengvvdaflKiaDFGlA
                      i++ ++r +e LH+++i+HRDLK+ N  l+++ +    + i+ F l 
   mFLJ00113   181 TVVIFYDVVRVVEALHQKNIVHRDLKLGNMVLNKRTHR---ITITNFCLG 227  

                   kklst.sss.lttfvGTpwYmAPEvllggngygtkvDvWSlGvilyellt
                   k+l  + +  l++  G+p Y++P vl g+++ g+++D+W+lGv+l+ +l 
   mFLJ00113   228 KHL-VsEGDlLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLY 276  

                   GkpPFsgevqdsldqlqlirkilgpplefdspewdsisrsefrrlpnlse
                   G++PF+++      +++l+rki+ +++ ++++   s             e
   mFLJ00113   277 GQFPFYDS-----IPQELFRKIKAAEYTIPEDGRVS-------------E 308  

                   eakdLikkcLnkDPskRltaeeilqHPwf<-*
                   +   Li+k+L +DP++Rl a+++l+   +   
   mFLJ00113   309 NTVCLIRKLLVLDPQQRLAAADVLEA--L    335  

Pkinase_Tyr: domain 1 of 1, from 42 to 335: score -121.8, E = 0.00027
                   *->lklgkkLGeGaFGeVykGtlkgsgegtkikVAVKtLkeigasseeie
                      ++lg  LG      ++++ ++               k+ g+++    
   mFLJ00113    42    FVLGPRLGNSPVPSIVQCLAR---------------KD-GTDD---- 68   

                   redFlrEAsiMkklGdHpNiVrLl.....GvctkegePggpg.lyiVtEy
                               +l    +i+ L +++++G+ ++ +e    g++++ tEy
   mFLJ00113    69 ----------FYQL----KILTLEergeqGIESQ-EER--QGkMLLHTEY 101  

                   megGdLldfLrkhr....................................
                       +Ll+ L+++ +  ++++  ++++ +  +++++++  ++ +++    
   mFLJ00113   102 ----SLLSLLHTQDgvvhhhglfqdrtceavedtesgrmvkkmkkriclv 147  

                   ........................egrpLtlkdLlsfalQiAkGMeYLes
                    +    ++ ++++ +  + ++    +++L+  + + + +++ +  e L++
   mFLJ00113   148 ldclcahdfsdktadlinlqhyviKEKRLSERETVVIFYDVVRVVEALHQ 197  

                   knfvHRDLAARNcLVse.nlvVKIsDFGLaRdiynddyYvrkkgggklPv
                   kn+vHRDL   N  ++++++ + I+ F L + + ++++   k +  +   
   mFLJ00113   198 KNIVHRDLKLGNMVLNKrTHRITITNFCLGKHLVSEGDL-LKDQ--RGSP 244  

                   kWmAPEslkygkF.tskSDVWSFGVlLWEiftlGeqPFYpgmsneevlel
                      +P +l+ + ++   SD W+ GV+L+ ++  G+ P +++  ++e++ +
   mFLJ00113   245 AYISPDVLSGRPYrGKPSDMWALGVVLFTMLY-GQFP-FYDSIPQELFRK 292  

                   lyedGyRLprPenCPdelYdlMlqCWaedPedRPtFselverL<-*
                   +    y  p     ++    l+++    dP++R   ++++e L   
   mFLJ00113   293 IKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEAL    335  

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