hmmpfam - search a single seq against HMM database HMMER 2.1.1 (Dec 1998) Copyright (C) 1992-1998 Washington University School of Medicine HMMER is freely distributed under the GNU General Public License (GPL). - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - HMM file: /data11/genetics/InterProScan/iprscan/data/smart.HMMs Sequence file: /cdna4/rodent/full/goal/mbg/mbg21780/w3open/interpro/cnk_1/seq.in - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: mFLJ00068 ( 1002 res) mbg21780 Scores for sequence family classification (score includes all domains): Model Description Score E-value N -------- ----------- ----- ------- --- RhoGEF Guanine nucleotide exchange factor for Rho/R 103.3 2.8e-26 1 PH Pleckstrin homology domain. 28.3 0.001 1 Parsed for domains: Model Domain seq-f seq-t hmm-f hmm-t score E-value -------- ------- ----- ----- ----- ----- ----- ------- RhoGEF 1/1 589 761 .. 1 211 [] 103.3 2.8e-26 PH 1/1 775 882 .. 1 82 [] 28.3 0.001 Alignments of top-scoring domains: RhoGEF: domain 1 of 1, from 589 to 761: score 103.3, E = 2.8e-26 *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl vl E+++TEr+YVr L + ++++ +L++++ +p + + +l mFLJ00068 589 VLAEMVATEREYVRALDYTIQNYFPELDRPD----VPQGLRGQRAHL 631 FgpNieeiyefHrrFLd.eLeerveewllskdlKsernsviedsgerigd Fg N+e + +fH +F+++eLe++ +++r+++ mFLJ00068 632 FG-NLEKLRDFHYNFFLrELEACT------------------RHPPRVAH 662 vFlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeies Fl + ++ + Y+ Y +n+p++ +l + +F++ + + mFLJ00068 663 AFLRH--VSSIGHHYALYSKNKPRSDALMTN----YGHTFFKEKQQALGD 706 kpncrsksearltLeslLikPvQRltkYpLLLkellkhtppdhedredLk + l+L s+L+kP+Q+ kY LLL+el + + + L+ mFLJ00068 707 H----------LDLASYLLKPIQHMSKYALLLQELARACGGPAQELGALQ 746 kAleaikelasqvNe<-* A+ +++ +++ N+ mFLJ00068 747 AAQSLVHFQLRHGND 761 PH: domain 1 of 1, from 775 to 882: score 28.3, E = 0.001 *->vikeGwLlkks......k.swkkryfvLfngvLlyyksk........ + +G+L ++ + + +++ r ++Lf+ Ll+ k+++++ + + mFLJ00068 775 LKEQGQLVRQDeftvraGrHKACRRVFLFEELLLFSKPRrgpagvdi 821 .kpkgsipLsgcsvre.p....cFeivt.dr....tlllqAeseeereeW ++k s+ +s + + Fei+++ r+ ++ ++lqA++ +++ W mFLJ00068 822 fTYKRSFKVSLHDPDLcLqcpiRFEIWFrRRkardLFVLQASDVATKQAW 871 vealqsaiaka<-* + + +++ ++ mFLJ00068 872 TADISRLLWRQ 882 //