hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /data11/genetics/InterProScan/iprscan/data/smart.HMMs
Sequence file:            /cdna4/rodent/full/goal/mpm/mpm05346/w3open/interpro/cnk_1/seq.in
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Query:  mFLJ00018  ( 1372 res)   mpm05346

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N 
-------- -----------                                    -----    ------- ---
RhoGEF   Guanine nucleotide exchange factor for Rho/R   178.4      7e-49   1
PH       Pleckstrin homology domain.                     43.1    3.8e-08   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
RhoGEF     1/1     134   310 ..     1   211 []   178.4    7e-49
PH         1/1     336   441 ..     1    82 []    43.1  3.8e-08

Alignments of top-scoring domains:
RhoGEF: domain 1 of 1, from 134 to 310: score 178.4, E = 7e-49
                   *->vlkELlqTErnYVrdLkilvevflkpLkkeakssllpllspdevktl
                      v++E+++TEr+YVrdL+ +ve +l pL++         l +++v tl
   mFLJ00018   134    VAREIVETERAYVRDLRSIVEDYLGPLMDGR----ALGLNMEQVGTL 176  

                   FgpNieeiyefHrrFLdeLeerveewllskdlKsernsviedsgerigdv
                   F  Nie+iyef++++L++Le ++                   s   i+ +
   mFLJ00018   177 FA-NIEDIYEFSSELLEDLEGCS-------------------SAGGIAEC 206  

                   FlklfsaeeffkiYseYcsnhpdalellkkLmkkkknpaFqkflkeiesk
                   F++    +e+f+iY+ Yc n+p++l+ll++L     +p+   +l+e++++
   mFLJ00018   207 FVQR---SEDFDIYTLYCMNYPSSLALLREL---SVSPPATLWLQERQAQ 250  

                   pncrsksearltLeslLikPvQRltkYpLLLkellkhtpp..dhedredL
                    +++      l+L+s+L+kPvQR++kY+LLL+el kh  +++d+  re++
   mFLJ00018   251 LRHS------LPLQSFLLKPVQRILKYHLLLQELGKHWAEgpDSGGREMV 294  

                   kkAleaikelasqvNe<-*
                   ++A+ +++ +a ++N+   
   mFLJ00018   295 EEAIVSMTAVAWYIND    310  

PH: domain 1 of 1, from 336 to 441: score 43.1, E = 3.8e-08
                   *->vikeGwLlkks..........k.swkkryfvLfngvLlyyksk....
                      +   G L   ++ +++++++++ +  +r ++Lf+++Ll  k ++++ 
   mFLJ00018   336    LSAFGELVLEGtfrggggggpRlRGGERLLFLFSRMLLVAKRRgpey 382  

                   kpkgsipLsgcsvre.p....cFeivt.dr...tlllqAeseeereeWve
                   ++kg i+  ++sv+e+p+++ +F+++  + +++++l+qA+++ee++ W++
   mFLJ00018   383 TYKGHIFCCNLSVSEtPrdplGFKVSDlTIpkhRHLFQAKNQEEKRLWIH 432  

                   alqsaiaka<-*
                   +lq++  ++   
   mFLJ00018   433 CLQRLFFEN    441  

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