FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0083.ptfa, 1078 aa
vs ./tmplib.26680 library
1767939 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 4.5538+/-0.00449; mu= 18.0150+/- 0.302
mean_var=82.9833+/-18.718, 0's: 0 Z-trim: 5 B-trim: 67 in 1/35
Lambda= 0.1408
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 39, opt: 27, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA0054 ( 1617 res) mbg06166 (1617) 186 49 7.4e-06
mKIAA1769 ( 1622 res) mtg00072 (1622) 181 48 1.5e-05
mKIAA0560 ( 1500 res) mbg02505 (1500) 180 48 1.6e-05
mKIAA0625 ( 778 res) mpm03100 ( 778) 168 45 5.9e-05
mKIAA1631 ( 1027 res) mej00871 (1027) 160 43 0.00022
>>mKIAA0054 ( 1617 res) mbg06166 (1617 aa)
initn: 227 init1: 90 opt: 186 Z-score: 197.5 bits: 48.9 E(): 7.4e-06
Smith-Waterman score: 241; 25.056% identity (30.939% ungapped) in 447 aa overlap (643-1038:643-1055)
620 630 640 650 660
mKIAA0 IDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVL--LSKDY--TLIVGMPG
:: :..:. . :: . .::.: :
mKIAA0 DNAVLFPDISMTPTIPWSPNRQWDEQLDPRLNAKQKEAVLAITTPLSIQLPPVLIIGPYG
620 630 640 650 660 670
670 680 690 700 710
mKIAA0 TGKTTTIC-ALVRILSACGFSVLLTSYTHSAVDNILLK--LAKF-KVG---------FLR
:::: :. : .::. .:. ....::.: . .: : . ..: ..:
mKIAA0 TGKTFTLAQAAKHILQQQETRILICTHSNSAAD-LYIKDYLHPYVEAGNPQARPLRVYFR
680 690 700 710 720 730
720 730 740 750 760
mKIAA0 LGQSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATT------CMGINHPIFS
. ::: .... : ..: .. . :.. . . .:.: :. .: :
mKIAA0 NRWVKTVHPVVHQYCL--ISSTQSTFQMPQKEDILKHRVVVVTLSTSQYLCQLDLEPGF-
740 750 760 770 780
770 780 790 800 810 820
mKIAA0 RKTFDFCIVDEASQISQPVCLGPLFFS---RRFVLVGDHQQLPPLVVNREARALGMSESL
: ..:::.: . . :: .. :.::.:::.:: :.: .. :: .. ::
mKIAA0 ---FTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLHVSL
790 800 810 820 830 840
830 840 850 860 870 880
mKIAA0 FKRLERNESAV----VQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKD
. :: .. : . : .:: .. :.. ...: : ::: .. . : ::
mKIAA0 LDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQ--------PAHKD
850 860 870 880 890
890 900 910 920 930 940
mKIAA0 ARLSLQLYADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTS
: ... ... : : .. . . :.. . :.:: : : ..
mKIAA0 FY-PLTFFTARGED-----VQEKNSTAFYNNAEVFEVVERVE--------ELRRKWPVAW
900 910 920 930 940
950 960 970 980 990 1000
mKIAA0 TFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVR-
. : .:::..:: .:. : : .. .. :.:. : . ::.. ....: ::
mKIAA0 GKLDDG----SIGVVTPYADQVFRIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRT
950 960 970 980 990
1010 1020 1030 1040
mKIAA0 --------------------SNEDGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLKRF
:.:: : .:.... ::.:.:::. . ..:. .:
mKIAA0 RHTCKHKQTPIKKKEQLLEDSTEDLDYG-FLSNYKLLNTAITRAQSLVAVVGDPVALCSI
1000 1010 1020 1030 1040 1050
1050 1060 1070
mKIAA0 PPLGTLFDHLNAEQLILDLPSREHESLSHILGDCQRD
mKIAA0 GRCRKFWERFIALCHENHSLHGITFEQIKAQLEALELKKTYVLNPLAPEFIPRALRLQHS
1060 1070 1080 1090 1100 1110
>>mKIAA1769 ( 1622 res) mtg00072 (1622 aa)
initn: 147 init1: 118 opt: 181 Z-score: 192.0 bits: 47.8 E(): 1.5e-05
Smith-Waterman score: 207; 26.545% identity (34.434% ungapped) in 275 aa overlap (795-1055:1379-1604)
770 780 790 800 810 820
mKIAA0 HPIFSRKTFDFCIVDEASQISQPVCLGPLFFSRR--FVLVGDHQQLPPLVVNREARALGM
::.. ::.:::.:: :.: ... ..:::
mKIAA1 ITLHHRIRQAPNPYAAEIRKFDAQLREGKIFSKEDLVVLLGDHKQLRPVVKSEQLQSLGM
1350 1360 1370 1380 1390 1400
830 840 850 860 870 880
mKIAA0 SESLFKRLERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKD
..:::.: .:. ...: .::::.. : :. . :.:::. :: :.
mKIAA1 DRSLFERYHRD---AIMLDTQYRMHKDICSFPSVEFYGGKLKTWSD-----------LR-
1410 1420 1430 1440 1450
890 900 910 920 930 940
mKIAA0 ARLSLQLYADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTS
:: : . : . .: : . .: . :: .:.: .
mKIAA1 -RL-----------PSILG--HTGKPSCSVIFGSVQGHEQ------------KLLVSTED
1460 1470 1480
950 960 970 980 990 1000
mKIAA0 TFIKAGCSPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRS
.. .: .. .. : :. :. .: : :... : :: . ..:: ::.
mKIAA1 GNENSRANPEEVTQVVSVR-------GLMQRGVTG-VTVTSITKSQGSEWRYVIVSTVRT
1490 1500 1510 1520 1530
1010 1020 1030 1040 1050
mKIAA0 NEDGTLGEL-LKDW-----------RRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDH
. . . :.: ...:::.:::.. : ..:. :. : :.:
mKIAA1 CPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDF
1540 1550 1560 1570 1580 1590
1060 1070
mKIAA0 LNAEQLILDLPSREHESLSHILGDCQRD
.:..
mKIAA1 CEAQHSLVSAEKVRVQRKSALSS
1600 1610 1620
>>mKIAA0560 ( 1500 res) mbg02505 (1500 aa)
initn: 236 init1: 71 opt: 180 Z-score: 191.3 bits: 47.6 E(): 1.6e-05
Smith-Waterman score: 300; 27.249% identity (32.188% ungapped) in 378 aa overlap (721-1074:1026-1369)
700 710 720 730 740 750
mKIAA0 LTSYTHSAVDNILLKLAKFKVGFLRLGQSHKVHPDIQKFTEEEICRSRSIASLAHLEELY
:. ....: :. :: .. .: :
mKIAA0 YFANAPQPIFKGRSYEEDMEIAEGCFRHIKKIFTQLEEFRASELLRS-GLDRSKYL--LV
1000 1010 1020 1030 1040 1050
760 770 780 790
mKIAA0 NSHPIVATTCMGINHPIFSRK-------TFDFCIVDEASQISQPVCLGPLF-------FS
. :.: :: .: ..:. .: ...::.:: . . ::. ::
mKIAA0 KEAKIIAMTC---THAALKRHDLVKLGFKYDNILMEEAAQILEIETFIPLLLQNPQDGFS
1060 1070 1080 1090 1100
800 810 820 830 840 850
mKIAA0 R--RFVLVGDHQQLPPLVVNRE-ARALGMSESLFKRLERNESAVVQLTVQYRMNRKIMSL
: :....:::.::::.. : . .: .::: :. : .:.: .: : .. .:
mKIAA0 RLKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNL
1110 1120 1130 1140 1150 1160
860 870 880 890 900 910
mKIAA0 SN-KLTYAGKLECGSDRVANAVLALPNLKDARLSLQLYADYSDSPWLAGVLEPDNPVCFL
: . :.: : ::... : .: . . . :: : .
mKIAA0 YNWRYKNLGNLP--------HVQLLPEFSTANAGLLYDFQLINVEDFQGVGESE------
1170 1180 1190 1200 1210
920 930 940 950 960 970
mKIAA0 NTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGCSPSDIGVIAPYRQQLRIISDLLA
: : .: : ::. .: : . : . :.... : : ..: :..
mKIAA0 -----PNPYFYQNLG-----EAEYVVALFMYMCLLGYPADKISILTTYNGQKHLIRDIIN
1220 1230 1240 1250 1260
980 990 1000 1010 1020
mKIAA0 RSS-----VGMV-EVNTVDKYQGRDKSLILVSFVRSNEDGTLGELLKDWRRLNVALTRAK
: .: .:.:::..::.... ::.:.::. : : .: ::: ::..::.
mKIAA0 RRCGNNPLIGRPNKVTTVDRFQGQQNDYILLSLVRTRAVGHL----RDVRRLVVAMSRAR
1270 1280 1290 1300 1310 1320
1030 1040 1050 1060 1070
mKIAA0 HKLILLGSVSSLKRFPPLGTLFDHLNAEQLILDLPSREHESLSHILGDCQRD
: ... :: .. : :..:.:. : : . : :. :.
mKIAA0 LGLYIFARVSLFQNCFELTPAFSQLTARPLHLHIIPTEPFPTSRKNGERPPHEVQVIKNM
1330 1340 1350 1360 1370 1380
mKIAA0 PQMANFVYNMYMHLIQTTHHYHQTFLQLPPAMVEEGEEGQSQETEMEAEEETVSAQGNLT
1390 1400 1410 1420 1430 1440
>>mKIAA0625 ( 778 res) mpm03100 (778 aa)
initn: 361 init1: 148 opt: 168 Z-score: 181.4 bits: 44.8 E(): 5.9e-05
Smith-Waterman score: 259; 28.846% identity (34.221% ungapped) in 312 aa overlap (773-1038:237-545)
750 760 770 780 790 800
mKIAA0 LAHLEELYNSHPIVATTCMGINHPIFSRKTFDFCIVDEASQISQPVCLGPLFFS-RRFVL
:. :::::.: . :.::. ...:
mKIAA0 ILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLSPLIHRCNKLIL
210 220 230 240 250 260
810 820 830 840 850
mKIAA0 VGDHQQLPPLVVNREARALGMSESLFKR----LERN-------ESAVVQLTVQYRMNRKI
::: .:::: :.. .:. :...:.. : ::.: . :.:::.::::. :
mKIAA0 VGDPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLTIQYRMHPDI
270 280 290 300 310 320
860 870 880 890 900
mKIAA0 MSLSNKLTYAGKLECGSDRVANAV---LALPNLKDARLSLQLYADYSDSPWLAGVLEPDN
. .. .: .:. ..:..... : ... .. :. .: :
mKIAA0 CLFPSNYVYNKNLK--TNRLTESIRCSSEWPFQPYLVFDVGDGSERRDNDSYINVQEIKL
330 340 350 360 370 380
910 920 930 940 950
mKIAA0 PVCFLNTDKVPAPE-QVENGGVSNVTEARLIVF---LTSTFIKAGC-SPSDIGVI-----
. ... : . . .: :. . .:. .. : . : : : .: .:
mKIAA0 VMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGLLQPIMMGESRQQDS
390 400 410 420 430 440
960 970 980 990
mKIAA0 -APYRQQ----LRIISDLLARSSV---------------GMVEVNTVDKYQGRDKSLILV
: .:: . :: :. :.: : .::.::: .:::.:. :.:
mKIAA0 EASKQQQKSSEFMHASDELGSSTVTQSGISSLENGATHTGPAEVDTVDAFQGRQKDCIIV
450 460 470 480 490 500
1000 1010 1020 1030 1040 1050
mKIAA0 SFVR-SNEDGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQL
. :: : .:..: .: . .::::..::::..:..:: . .:
mKIAA0 TCVRASAVQGSIG-FLASLQRLNVTITRAKYSLFILGHLRTLMENQHWYELIQDAQKRGA
510 520 530 540 550 560
1060 1070
mKIAA0 ILDLPSREHESLSHILGDCQRD
mKIAA0 IIKTSDPNYRHDAMKILKTHPPATAPEAPRPQGGLPSNRLDSGLATTSFAASLYHTPSDT
570 580 590 600 610 620
>>mKIAA1631 ( 1027 res) mej00871 (1027 aa)
initn: 302 init1: 82 opt: 160 Z-score: 171.2 bits: 43.3 E(): 0.00022
Smith-Waterman score: 316; 25.345% identity (30.061% ungapped) in 580 aa overlap (528-1049:414-960)
500 510 520 530 540 550
mKIAA0 NLVRTEPVSRVCDGQYLHNFQRKNGPMPATNLMAGDRI--ILSGEERKLFALS-KGYVKK
... ::.. .::.: .. .. ::.:.:
mKIAA1 LDSVPMTWDPVDQNPRLLTLEVPGVAESRPSVLRGDHLFALLSSETQQDDPVTYKGFVHK
390 400 410 420 430 440
560 570 580 590 600
mKIAA0 MNKAAV-----TCLLDRNLSTLPATTVFRLDREERHGDISTPLGNLSKLMESTDPSKRLR
.. : : ::.: .. : . : ..:. :: . .: : :
mKIAA1 VELDRVKLSFSTSLLSRFVDGLTFKVNFTFNRQ--------PLRVQHRALELTG-----R
450 460 470 480 490
610 620 630 640 650 660
mKIAA0 ELIIDFREPQFIAYLSSVLPHDAKDTVANILKGLNKPQRQAMKRVLLSKDYT---LIVGM
.. . : . :.:: :.: . . : : ::::... . .: :
mKIAA1 WVLWPMLFP-VASRGVSLLPSDVKFKLYDRSLESNPEQLQAMKHIVRGTTRPAPYIIFGP
500 510 520 530 540
670 680 690 700 710 720
mKIAA0 PGTGKTTTICALVR--ILSACGFSVLLTSYTHSAVDNILLKL-AKFKVGFLRLGQSHK--
::::::.:. .. . .: . ..:..: . .: ... .. :: .
mKIAA1 PGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDI
550 560 570 580 590 600
730 740 750 760 770
mKIAA0 --VHPDIQKFTEEEICRSRSI-ASLAHLEE--LYNSHPIVATTCMGINHPIFSRKTFDFC
: ::. . . ... . . ::.. . . :.:. .. . :: :
mKIAA1 RMVPEDIKTCCNWDAKKGEYVYPAKKHLQQYRVLITTLITASRLVSAQFPI---DHFTHI
610 620 630 640 650 660
780 790 800 810 820
mKIAA0 IVDEASQISQP---VCLGPLFFSR-------RFVLVGDHQQLPPLVVNREARALGMSESL
..:::.. .: : .. :. . ..::.:: .:: :.. . : :.. ::
mKIAA1 FIDEAGHCMEPESLVAIAGLMDVKETGNPGGQLVLAGDPRQLGPVLRSPLALKHGLGYSL
670 680 690 700 710 720
830 840 850 860 870
mKIAA0 FKRLERNESA------------VVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAV
..:: .: ...: .:: . :... :.: : :.:. .: :
mKIAA1 LERLLAYNSLYKKGPNGYDPQFITKLLRNYRSHPTILDIPNQLYYDGELQACADVVDRER
730 740 750 760 770 780
880 890 900 910 920 930
mKIAA0 LALPNLKDARLSLQLYADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEA
. . : : . . : ..: :.: :: : . :.. .
mKIAA1 FC----RWEGLPQQGFPIIFHGVMGKDEREGNSP-SFFN------PE--EAATVTSYLKQ
790 800 810 820 830
940 950 960 970 980
mKIAA0 RLIVFLTSTFIKAGCSPSDIGVIAPYRQQ---LRIISDLLARSSVGM-----VEVNTVDK
: .: :: :: ..:::.:::.: .: : : :. ..:..:..
mKIAA1 LLAP--SSKKGKARLSPRNVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEE
840 850 860 870 880 890
990 1000 1010 1020 1030
mKIAA0 YQGRDKSLILVSFVRSNE-------DGTLGELLKDWRRLNVALTRAKHKLILLGSVSSLK
.::...:.::.: :::.. : .:: .::. .:.:::.:::: ::..:. :
mKIAA1 FQGQERSVILISTVRSSQSFVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIVVGNPLLLG
900 910 920 930 940 950
1040 1050 1060 1070
mKIAA0 RFPPLGTLFDHLNAEQLILDLPSREHESLSHILGDCQRD
. : :...
mKIAA1 HDPDWKTFLEFCKENGGYTGCPFPAKLDLQQGQDLLQGLSKLSPSTSGPRRHQNLPQERE
960 970 980 990 1000 1010
1078 residues in 1 query sequences
1767939 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:11:52 2006 done: Mon Mar 27 10:11:53 2006
Scan time: 1.050 Display time: 0.280
Function used was FASTA [version 3.4t11 Apr 17, 2002]