FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA1008.ptfa, 451 aa
vs ./tmplib.26680 library
1768566 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 4.9416+/-0.00383; mu= 12.6742+/- 0.256
mean_var=80.1619+/-18.159, 0's: 0 Z-trim: 4 B-trim: 0 in 0/36
Lambda= 0.1432
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA1955 ( 1073 res) mtj00267 (1073) 892 194 3.4e-50
mFLJ00327 ( 881 res) mid41093 ( 881) 561 126 1.1e-29
mKIAA1769 ( 1622 res) mtg00072 (1622) 297 72 4.7e-13
>>mKIAA1955 ( 1073 res) mtj00267 (1073 aa)
initn: 899 init1: 362 opt: 892 Z-score: 993.6 bits: 194.3 E(): 3.4e-50
Smith-Waterman score: 984; 41.606% identity (45.722% ungapped) in 411 aa overlap (58-447:210-604)
30 40 50 60 70 80
mKIAA1 SCQKTTIHVSSRLNTVPRYLNLKIVTYFSGEEYVKSLTANPELIDRLAYLSDEMNEIES-
... .: : .: : . : . : ::
mKIAA1 IVMVTEDEEAIQKYGSETEGVFVISFKNYLDNFWPDLKAAHDLCDSILQ-SRRERETESQ
180 190 200 210 220 230
90 100 110 120 130
mKIAA1 ---GKIIFSEHLPLSKLQQGIKSGSYLQGTFRASREN-YLEATVWIHGDKEEE----KEI
:: . ::::: :. ::::: :.:: . .... .:: : .:: . .. ..:
mKIAA1 ETHGKE-YPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLHGASSKDSGLVSDI
240 250 260 270 280 290
140 150 160 170 180 190
mKIAA1 LIQGIKHLNRAVHEDIVAVELLPRSQWVAPSSVVLDDEGQNEDDVEKDEERELLLKTAVS
::.: : ::..: :.:.::.::.:.: . .... :.:..: . . : :
mKIAA1 LIHGSKARNRSIHGDVVVVEMLPKSEWKGRTAAL----GENDSDDKASGESP-------S
300 310 320 330 340
200 210 220 230 240 250
mKIAA1 EKMLRPTGRVVGIIKRNWRPYCGML-SKSDI----KESRRHLFTPADKRIPRIRIETRQA
: : ::::::::...::: : . :: .. :.... : :: : :::.::: :.::
mKIAA1 EPM--PTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQA
350 360 370 380 390 400
260 270 280 290 300 310
mKIAA1 SALEGRRIIVAIDGWPRNSRYPNGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
::. :..: ::.: .: :::::::. :: .:. : : ..:.:... :::.: .
mKIAA1 EALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMC
410 420 430 440 450 460
320 330 340 350 360
mKIAA1 FLP----RMPWSITEEDMKNREDLR--HLCVCSVDPPGCTDIDDALHCRELSNGNLEVGV
.: . ::... .. ..:.::: :: : :.:: :: :.::.: : :.:::::.::
mKIAA1 EMPVNTPENPWKVSPKEEQERKDLRTTHL-VFSIDPKGCEDVDDTLSVRTLNNGNLELGV
470 480 490 500 510 520
370 380 390 400 410 420
mKIAA1 HIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIW
:::::.::. :.. .: :. :.:: :: ..: ::.: .::..:::: ..::: : : .:
mKIAA1 HIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMW
530 540 550 560 570 580
430 440 450
mKIAA1 EMNHNA-EILKTRFTKSVINSKVSV
:..... :: :. . ...: :
mKIAA1 ELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLE
590 600 610 620 630 640
>>mFLJ00327 ( 881 res) mid41093 (881 aa)
initn: 642 init1: 433 opt: 561 Z-score: 625.0 bits: 125.8 E(): 1.1e-29
Smith-Waterman score: 668; 31.377% identity (38.936% ungapped) in 443 aa overlap (88-447:58-497)
60 70 80 90 100 110
mKIAA1 EEYVKSLTANPELIDRLAYLSDEMNEIESGKIIFSEHLPLSKLQQGIKSGSYLQGTFRAS
: :: .. ...:.: :. .::..: .
mFLJ00 RGVSSVVGPSAVGASPGDKKSKNKSMRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRIN
30 40 50 60 70 80
120 130 140 150 160 170
mKIAA1 RENYLEATVWIHGDKEEEKEILIQGIKHLNRAVHEDIVAVELLPRSQW--VAPSS-----
... :: . . . ...:.:.:. :::.. :.:.:.:::..:: : : :
mFLJ00 PKKFHEAFI---PSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEDQWKAVKPESNDKEI
90 100 110 120 130 140
180
mKIAA1 -----------------------------VVLD---DEGQNED-----------------
:... :....::
mFLJ00 EATYEADIPEEGCGHHPLQQSRKGWSGPDVIIEAQFDDSDSEDRHGNTSGLVDGVKKLSI
150 160 170 180 190 200
190 200 210 220
mKIAA1 ------------DVEKDEERELLLKT-AVSEKMLRPTGRVVGII-KRNWRPYCGMLSKSD
: :::. . : ..::: :. ...:: :. :.. : :.:.
mFLJ00 STPDRGKEDSSTPVMKDENTPIPQDTRGLSEKSLQKSAKVVYILEKKHSRAATGILKLLA
210 220 230 240 250 260
230 240 250 260 270
mKIAA1 IKES----RRHLFTPADKRIPRIRIETR--------QASALEGRRIIVAIDGWPRNSRYP
:.: . ::.:.:.:.::: . . . . . . .: : : .. .
mFLJ00 DKNSDLFKKYALFSPSDHRVPRIYVPLKDCPQDFMTRPKDFANTLFICRIIDWKEDCNFA
270 280 290 300 310 320
280 290 300 310 320 330
mKIAA1 NGHFVKNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPR-MPWSITEEDMKNREDLR
:...:.::..:: : ::: .: :. : . ::. :: ::. .::.: ... .:.:::
mFLJ00 LGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQSLPWTIPPDEVGKRRDLR
330 340 350 360 370 380
340 350 360 370 380 390
mKIAA1 HLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTVY
. :. ..:: :.:::: ::.:..:..::::::::::.:. :..::. .:.:.:.::
mFLJ00 KDCIFTIDPSTARDLDDALACRRLTDGTFEVGVHIADVSYFVPEGSSLDKVAAERATSVY
390 400 410 420 430 440
400 410 420 430 440 450
mKIAA1 LCEKRIDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKTRFTKSVINSKVSV
: .: . :.:.:: .:::: .:.:.:: ::... ...::. : ...: :
mFLJ00 LVQKVVPMLPRLLCEELCSLNPMTDKLTFSVIWKLTPEGKILEEWFGRTIIRSCTKLSYD
450 460 470 480 490 500
mFLJ00 HAQSMIENPTEKIPEEELPPISPEHSVEEVHQAVLNLHSIAKQLRRQRFVDGALRLDQLK
510 520 530 540 550 560
>>mKIAA1769 ( 1622 res) mtg00072 (1622 aa)
initn: 231 init1: 120 opt: 297 Z-score: 326.8 bits: 71.5 E(): 4.7e-13
Smith-Waterman score: 304; 30.827% identity (34.167% ungapped) in 266 aa overlap (206-447:318-581)
180 190 200 210 220
mKIAA1 EGQNEDDVEKDEERELLLKTAVSEKMLRPTGRVVGIIKR------------NWRPYC---
:::.:..:: .: :
mKIAA1 NCGMAFTGDEVLVQILGPAGDDRCVPGSLQGRVMGVLKRRRHELAFVCRMDEWDPRIMIP
290 300 310 320 330 340
230 240 250 260 270
mKIAA1 --GMLSKSDIKESRRHLFTPADK----RIPRIRIETRQASALEGRRIIVAIDGWPRNSRY
: ..: . : . .: . .. :.: :: . : . : : : . :
mKIAA1 INGSVTKIFVAEMKDPQQVPIHRLIQGQVQRVRHETLKPEDRSTRLFWVRIVLWRERFYY
350 360 370 380 390 400
280 290 300 310 320 330
mKIAA1 PNGHFVKNLGDVGEKETETEVLLLEHDVP-HQPFSQAVLSFLPRMPWSITEEDMKNREDL
: : .. : . : .: ::: . : : .: . : :. : . .:::
mKIAA1 PLGIVLEVLPKAITWEQGLYILDLEHGLKAHTPDPASVSKALQRYR-SELNTAAGHREDY
410 420 430 440 450 460
340 350 360 370 380 390
mKIAA1 RHLCVCSVDPPGCTDIDDALHCRELSNGNLEVGVHIADVSHFIRPGNALDQESARRGTTV
::. . .::: : ..:::: :.:. ::.::::::. .. .::: :. ..::.
mKIAA1 RHFLTFTVDPQGACNLDDALSVRDLGP-VYEVAVHIADVASLVPKDGALDVEARQQGTVF
470 480 490 500 510 520
400 410 420 430 440 450
mKIAA1 YLCEKR-IDMVPELLSSNLCSLRSNVDRLAFSCIWEMNHNAEILKT-RFTKSVINSKVSV
: ... . :.: : .. :: . ::::.: . :.... .:. ::. :.: :
mKIAA1 YAPNREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFAPSIIRSDRQL
530 540 550 560 570 580
mKIAA1 SYEEAEELIKRHPGAGLELPAHLDSVEACVVAACYFSWMLRRQRLSAACYYEPPDEDSVL
590 600 610 620 630 640
451 residues in 1 query sequences
1768566 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:33:49 2006 done: Mon Mar 27 10:33:50 2006
Scan time: 0.670 Display time: 0.080
Function used was FASTA [version 3.4t11 Apr 17, 2002]