FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA4148.ptfa, 498 aa
 vs ./tmplib.26680 library

1768519 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 9.1303+/-0.00631; mu= -5.8136+/- 0.414
 mean_var=391.7306+/-94.029, 0's: 0 Z-trim: 11  B-trim: 0 in 0/36
 Lambda= 0.0648

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0845  ( 1046 res)   mbh00862                  (1046)  977  106 1.6e-23


>>mKIAA0845  ( 1046 res)   mbh00862                       (1046 aa)
 initn: 853 init1: 547 opt: 977  Z-score: 514.5  bits: 105.8 E(): 1.6e-23
Smith-Waterman score: 984;  43.218% identity (45.742% ungapped) in 435 aa overlap (70-487:36-463)

      40        50        60        70        80        90         
mKIAA4 SSSYRRMFGGSGTSSRPSSNRSYVTTSTRTYSLGSALRPSTSRSLYSSSPGGAYVTRSSA
                                     :::.    :. .::  .:: :    .:.:.
mKIAA0 APAPAMMSFGSADALLGAPFAPLHGGGSLHYSLSRKAGPGGTRSAAGSSSGFHSWARTSV
          10        20        30        40        50        60     

     100       110       120       130             140       150   
mKIAA4 VRLRSSVPGVRLLQDSVDFSLADAINTEFKN------TRTNEKVELQELNDRFANYIDKV
         . .:    :   .:.: :: :....  ..      .  .:: .:: ::::::.:::::
mKIAA0 SSVSASPSRFRGAASSTD-SL-DTLSNGPEGCVVAAVAARSEKEQLQALNDRFAGYIDKV
          70        80          90       100       110       120   

           160       170         180       190       200       210 
mKIAA4 RFLEQQNKILLAELEQLKGQ--GKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLA
       : :: .:. : .:   :. :  :.. .:.:::.:.::.:  : .:   ......:...: 
mKIAA0 RQLEAHNRSLEGEAAALRQQQAGRAAMGELYEREVREMRGAVLRLGAARGQLRLEQEHLL
           130       140       150       160       170       180   

             220       230       240       250       260       270 
mKIAA4 EDIMRLREKLQEEMLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHD
       ::: ..:..:.::  ::::::.. ... . ...:  ::..:..:...:::: ..:.. :.
mKIAA0 EDIAHVRQRLDEEARQREEAEAAARALARFAQEAEAARVELQKKAQALQEECGYLRRHHQ
           190       200       210       220       230       240   

             280            290        300       310       320     
mKIAA4 EEIQELQAQIQ-----EQHVQIDV-DVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKS
       ::. :: .:::     . ..: .. :. : :.:.:::..: : :. :...  ..:::.. 
mKIAA0 EEVGELLGQIQGCGAAQAQAQAEARDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRV
           250       260       270       280       290       300   

         330       340       350       360       370       380     
mKIAA4 KFADLSEAANRNNDALRQAKQESNEYRRQVQSLTCEVDALKGTNESLERQMREMEENFAL
       ..  :::::. :.::.:.:..: .:::::.:. : :..:::.:.::::::  :.:.    
mKIAA0 RLDRLSEAAKVNTDAMRSAQEEITEYRRQLQARTTELEALKSTKESLERQRSELEDRHQA
           310       320       330       340       350       360   

         390       400       410       420       430       440     
mKIAA4 EAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISL
       . :.:::.: .:..:..: : ::: .:::::::::::::::::::.::::::::: ::..
mKIAA0 DIASYQDAIQQLDSELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLEGEECRIGF
           370       380       390       400       410       420   

          450       460         470       480       490            
mKIAA4 -PLPTFSSLNLRETNLESLPLVDTH--SKRTLLIKTVETRDGQVINETSQHHDDLE    
        : : ::   : : .: ..: ..::   :   .::.::  . ...               
mKIAA0 GPSP-FS---LTE-GLPKIPSISTHIKVKSEEMIKVVEKSEKETVIVEGQTEEIRVTEGV
               430        440       450       460       470        

mKIAA0 TEEEDKEAQGQEGEEAEEGEEKEEEEGAAATSPPAEEAASPEKETKSRVKEEAKSPGEAK
      480       490       500       510       520       530        




498 residues in 1 query   sequences
1768519 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 11:03:20 2006 done: Mon Mar 27 11:03:21 2006
 Scan time:  0.720 Display time:  0.020

Function used was FASTA [version 3.4t11 Apr 17, 2002]