FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA3012.ptfa, 253 aa
 vs ./tmplib.26680 library

1768764 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 5.0626+/-0.00439; mu= 9.4900+/- 0.293
 mean_var=100.4545+/-23.498, 0's: 0 Z-trim: 7  B-trim: 0 in 0/36
 Lambda= 0.1280

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 36, opt: 24, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0118  ( 253 res)   mni13228                   ( 253)  530  108 5.2e-25
mKIAA4130  ( 194 res)   mie08042                   ( 194)  287   63 1.4e-11


>>mKIAA0118  ( 253 res)   mni13228                        (253 aa)
 initn: 545 init1: 432 opt: 530  Z-score: 541.4  bits: 107.7 E(): 5.2e-25
Smith-Waterman score: 530;  35.537% identity (38.222% ungapped) in 242 aa overlap (23-253:15-250)

               10        20        30        40           50       
mKIAA3 GSEWGRRLLYRNSLAHSSLSITCGAESWGGGCVSKGGGGG---GGGGSCSDMSSMNPEYD
                             ::..  :.:   .:.:::   .:::. .  .       
mKIAA0         KSRAREERAPRRRRCGVRR-GAGLGRRGSGGGMAAAGGGAAAAAGRA-----
                       10         20        30        40           

        60        70        80        90       100       110       
mKIAA3 YLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQRWDTAG
       : ::..:.:.. :::. :.::. .. .....:.:. ..:  . ... :: ..:  :::::
mKIAA0 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAG
         50        60        70        80        90       100      

       120       130       140       150       160       170       
mKIAA3 QERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLT
       ::::...   ::: ..: :.::::::..::..::.:..:. .. ....   .:::: :: 
mKIAA0 QERFHALGPIYYRDSNGAILVYDVTDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLE
        110       120       130       140       150       160      

       180       190       200       210             220        230
mKIAA3 TKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTM------AAEIKKRM-GPGATA
        .. :.   :. .:.:.:    .::::.  ..:. :. .      .:.. .:  : :.. 
mKIAA0 KERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQ
        170       180       190       200       210       220      

              240        250      
mKIAA3 GGAEKSNVKI-QSTPVKQSGGGCC   
       .:: . .:.: .. :  ::.::::   
mKIAA0 AGAARRGVQIIDDEPQAQSSGGCCSSG
        230       240       250   

>>mKIAA4130  ( 194 res)   mie08042                        (194 aa)
 initn: 255 init1: 156 opt: 287  Z-score: 300.3  bits: 62.7 E(): 1.4e-11
Smith-Waterman score: 294;  31.111% identity (34.356% ungapped) in 180 aa overlap (61-225:8-185)

               40        50        60        70        80        90
mKIAA3 GCVSKGGGGGGGGGSCSDMSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYIS
                                     ::...::.. ::.:::. :. : . : :. 
mKIAA4                        VMAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVP
                                      10        20        30       

              100       110       120       130       140       150
mKIAA3 TIGVDFKIRTIELDGKTIKLQRWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNV
       :.  .. .  ::.::: ..:  ::::::: .  .    :  .  :.. ... . .:..:.
mKIAA4 TVFENY-VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI
        40         50        60        70        80        90      

               160       170            180              190       
mKIAA3 -KQWLQEIDRYASENVNKLLVGNKCDL-----TTKKV-------VDYTTAKEFADSLG-I
        ..:  :. ..   ::  .::::: ::     : ...       :    ....:. .: .
mKIAA4 PEKWTPEVKHFCP-NVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAF
        100        110       120       130       140       150     

        200       210        220       230       240       250   
mKIAA3 PFLETSAKNATNVEQSF-MTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
        ..: :::.  .:.. : :.  : .. : :                            
mKIAA4 GYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL                   
         160       170       180       190                       




253 residues in 1 query   sequences
1768764 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 10:58:30 2006 done: Mon Mar 27 10:58:30 2006
 Scan time:  0.460 Display time:  0.010

Function used was FASTA [version 3.4t11 Apr 17, 2002]