FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0364.ptfa, 1026 aa
vs ./tmplib.26680 library
1767991 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 4.2861+/-0.00406; mu= 20.5407+/- 0.272
mean_var=87.7094+/-20.617, 0's: 0 Z-trim: 5 B-trim: 0 in 0/36
Lambda= 0.1369
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 39, opt: 27, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA3024 ( 898 res) mfj07190 ( 898) 164 43 0.00019
mKIAA0657 ( 782 res) mbg05167 ( 782) 163 43 0.0002
mKIAA3016 ( 714 res) mph00541 ( 714) 140 38 0.0045
>>mKIAA3024 ( 898 res) mfj07190 (898 aa)
initn: 106 init1: 55 opt: 164 Z-score: 172.1 bits: 43.2 E(): 0.00019
Smith-Waterman score: 201; 21.739% identity (25.000% ungapped) in 437 aa overlap (70-466:29-448)
40 50 60 70 80
mKIAA0 APWENITLWCKSPSRVSSKFLLLKDNSQMTWIRPPYKTFQ-----VS-----FFIGALTE
:: : ..: :: ..:. . .
mKIAA3 RSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEK
10 20 30 40 50
90 100 110 120 130 140
mKIAA0 SNTGLYRCCYWKEKGWSK---PSKILELEAPGQLPK--PIFWIQ-AET-PPLPGCNVNIF
:..: : : . : : : :. : . . : . .: :: : : .:..
mKIAA3 SDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPAEKGTTVKLE
60 70 80 90 100 110
150 160 170 180 190 200
mKIAA0 CHGWLQDLVFMLFKEGYTEPVDYQVPTG-TMAIFSIDNLAPENEGVYICRTHIQMLPTLW
: . . . .:.... .:. .. . .:. : :. :. : : : ..
mKIAA3 CFALGNPVPTILWRRADGKPIARKARRHKSNGILEIPNFQQEDAGSYECVAEN-------
120 130 140 150 160 170
210 220 230 240 250
mKIAA0 SEPSNPLKLVVAGLYPKPTLTAHPGPI-LAPGESLSLRCQGPIYGMTFALMR-LEDLKKS
:. .: : .. .: .:. . . : .: ::. .:.. : .: :..
mKIAA3 SRGKNVAKGQLT-FYAQPNWVQIINDIHVAMEESVFWECKAN--GRPKPTYRWLKNGDPL
180 190 200 210 220
260 270 280 290 300 310
mKIAA0 FYHKKPIKNEAYFYFQDLKIQDTGHYLCFYYDGSYRGSLLS--DILKIWVTDTFPKTWLL
. . . ... . . ....:.: : : . .: ..: .. : . : .: :
mKIAA3 LTRDRIQIEQGTLNITIVNLSDAGMYQCVAENK--HGVIFSSAELSVIAESPDFSRT--L
230 240 250 260 270 280
320 330 340 350 360 370
mKIAA0 VQPSPVIQMGQNVSLRCGGLMDGVGLALYKKGEEKPLQFLDASSNTGNNSFFLKNVTYRD
.. ....: .: ..: . . ..::.: :. . . . .... . ::: :
mKIAA3 LKRVTLVKVGGEVVIECKPKASPRPVYTWRKGREI-LRENERITISEDGNLRIINVTKSD
290 300 310 320 330 340
380 390 400 410 420 430
mKIAA0 AGIYSC---HYYLTWKTSIKMATYNTVELMVVAWPSSV-FKVGKTITLQCRVSHP-VLEF
:: :.: ... : ... .. . . ...:: :::. ::..:.: :.:.: :..
mKIAA3 AGSYTCIATNHFGTASSTGNVIVKDPTKVMVP--PSSMDVTVGESIVLPCQVTHDHSLDI
350 360 370 380 390 400
440 450 460 470
mKIAA0 SLEWEERTTFQKFSVDGD-------------FLITDIEGQGTGTYSCSYRIEAHPNTWSH
. : . :. ::: ..: .:. . .: : :
mKIAA3 VFTWTFNGHLIDFDKDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDKLSVAA
410 420 430 440 450 460
480 490 500 510 520 530
mKIAA0 RSKPLKLVGPAGFLTWNSILNEAVRVSLTMQLASLLLLVVWIRWKCRRLRLREAWLLGTA
mKIAA3 DLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVNTVP
470 480 490 500 510 520
>>mKIAA0657 ( 782 res) mbg05167 (782 aa)
initn: 104 init1: 65 opt: 163 Z-score: 171.6 bits: 43.0 E(): 0.0002
Smith-Waterman score: 192; 24.314% identity (27.679% ungapped) in 255 aa overlap (681-916:253-495)
660 670 680 690 700
mKIAA0 SEPSEALELVGTDILPKPVISASLPIRGQELQIRCKGWLEGLGFALYKKGEQEPVQ---Q
...::. : :: : . :. :
mKIAA0 FFTVTVTAPPERIVHPAARSLDLQFGAPGHVELRCEVAPAGSQVRWYKDGLEVEVSDALQ
230 240 250 260 270 280
710 720 730 740 750 760
mKIAA0 LGAVGREAFFTIQRMEDKDEGNYSCRTHTEMQPFKWSEPSEPLELVIKEMYPKPFFKTWA
::: : .:. . . .: :.: :.:. : :. : :.... : :.:.
mKIAA0 LGAEGPARTLTLPHAQPEDAGEYVCETRDEAVTFNVSLAELPVQFLAPEAAPNPL-----
290 300 310 320 330
770 780 790 800 810 820
mKIAA0 SPVVTPGSRVTFNCSTSHEHMSFILYKDGNEIASSDLAWGNPGGSTAHFLIISVGIGDGG
:.:: :...: :. . . ..:. . ... : . : .. .. :
mKIAA0 --CVVPGEPVVLSCELSRASAQVFWSHNGSPVQQGEGLELRAEGPRRILCIQAADLAHTG
340 350 360 370 380 390
830 840 850 860 870
mKIAA0 NYSCRY--------YDFSIW-SEPSNPVELVVTEFYPKPTLLAQPGPGKDITLQCRGPLP
:.:. .:.. .:: ::..:. : .. :: :. : . :
mKIAA0 VYTCQSGASPGAPSLSFNVQVAEP--PVRVVAPE---AAQTSVRSTPGGDLELVVHLSRP
400 410 420 430 440 450
880 890 900 910 920 930
mKIAA0 GVEFVLEHDGEE-APQ---QFSEDGDFVIDNLEG--KG-IGNYSCSYRLQAYPDIWSEPS
:. .:::. : : :. . : . ..: .: :.: :.
mKIAA0 GTPVRWYKDGERLASQGRVQLEQAGARQVLRVRGARRGDAGEYLCDAPQDSRIFIVSVEG
460 470 480 490 500 510
940 950 960 970 980 990
mKIAA0 DTLELVGAAGPVAQECTVGNIVRSTLIVVVVVALGIVLAVEWKKWPRLRTRGSETDGRDQ
mKIAA0 NHAPLIPTKTTSHPLDPFHLLYLTQLLSMVPTNAFMTVTVRGHLPFFQHPSIAGCIAQWI
520 530 540 550 560 570
>>mKIAA3016 ( 714 res) mph00541 (714 aa)
initn: 110 init1: 67 opt: 140 Z-score: 147.5 bits: 38.4 E(): 0.0045
Smith-Waterman score: 140; 22.628% identity (26.050% ungapped) in 274 aa overlap (216-466:104-364)
190 200 210 220 230 240
mKIAA0 GVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPILA-PGESLSLRCQGPIY
.::: .:..: : : ..:. :..
mKIAA3 SFVNASCAHPQLLKGRSIFTVSPDGFVCDDFPKPQITVQPETQSAIKGSDVSFTCSAASS
80 90 100 110 120 130
250 260 270 280 290
mKIAA0 G---MTFALMRLEDLKKSFYHKKPIKNEAYFYFQD---LKIQDTGHYLCF---YYDGSYR
. :::: . .. .. ..: :.. : ... . :.: : .. .::
mKIAA3 SDSPMTFAWKKDNEALQD----AEMENYAHLRAQGGELMEFTSEGKYQCVISNHFGSSYS
140 150 160 170 180
300 310 320 330 340 350
mKIAA0 GSLLSDILKIWVTDTFPKTWLLVQPSPVIQMGQNVSLRCGGLMDGVGLALYKK--GEEKP
.. : : . .: :: . . .:. : . :.:... . ..: : . :
mKIAA3 ---VKAKLTINMLPSFTKTPMDL----TIRAGAMARLECAAVGHPAPQIAWQKDGGTDFP
190 200 210 220 230 240
360 370 380 390 400
mKIAA0 L-QFLDASSNTGNNSFFLKNVTYRDAGIYSCHYYLTWKTSIKMATYNTVELMVVAWP---
. .. ::. .: .: :.::: . . :: ...: :
mKIAA3 AARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSVSANATLTVLETPSFLRPLLD
250 260 270 280 290 300
410 420 430 440 450 460
mKIAA0 SSVFKVGKTITLQCRVSHPVLEFSLEWEER-----TTFQKFSVDGD--FLITDIEGQGTG
.: : :.: .::: .. :.: . .: ..: . :. ..:.: . . .:
mKIAA3 RTVTK-GETAVLQC-IAGGSPPPRLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAG
310 320 330 340 350 360
470 480 490 500 510 520
mKIAA0 TYSCSYRIEAHPNTWSHRSKPLKLVGPAGFLTWNSILNEAVRVSLTMQLASLLLLVVWIR
:.:
mKIAA3 KYTCEMSNTLGTERGNVRLSVIPTPTCDSPHMTAPSLDGDGWATVGVVIIAVVCCVVGTS
370 380 390 400 410 420
1026 residues in 1 query sequences
1767991 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:18:56 2006 done: Mon Mar 27 10:18:57 2006
Scan time: 1.010 Display time: 0.100
Function used was FASTA [version 3.4t11 Apr 17, 2002]