# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mpf01029.fasta.nr -Q ../query/mKIAA0646.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
mKIAA0646, 749 aa
vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library
2727779818 residues in 7921681 sequences
statistics sampled from 60000 to 7904213 sequences
Expectation_n fit: rho(ln(x))= 5.3866+/-0.000195; mu= 12.3477+/- 0.011
mean_var=107.8419+/-20.399, 0's: 35 Z-trim: 103 B-trim: 104 in 1/66
Lambda= 0.123504
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 38, opt: 26, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7921681)
gi|73972753|ref|XP_864751.1| PREDICTED: similar to ( 880) 3712 672.9 1.5e-190
gi|73972755|ref|XP_538896.2| PREDICTED: similar to (1090) 3712 673.0 1.7e-190
gi|109070995|ref|XP_001117035.1| PREDICTED: simila (1272) 3586 650.6 1.1e-183
gi|21362895|sp|Q8VC56.1|RNF8_MOUSE RecName: Full=E ( 488) 3243 589.0 1.4e-165
gi|68534363|gb|AAH99079.1| Ring finger protein 8 [ ( 487) 2911 529.8 9.1e-148
gi|73972751|ref|XP_864730.1| PREDICTED: similar to ( 487) 2367 432.9 1.4e-118
gi|119366657|sp|Q2HJ46.1|RNF8_BOVIN RecName: Full= ( 487) 2308 422.4 2e-115
gi|194040433|ref|XP_001927699.1| PREDICTED: simila ( 512) 2290 419.2 1.9e-114
gi|90075162|dbj|BAE87261.1| unnamed protein produc ( 486) 2245 411.2 4.8e-112
gi|21362894|sp|O76064.1|RNF8_HUMAN RecName: Full=E ( 485) 2242 410.6 7e-112
gi|30584345|gb|AAP36421.1| Homo sapiens ring finge ( 486) 2242 410.6 7e-112
gi|62897089|dbj|BAD96485.1| ring finger protein 8 ( 485) 2238 409.9 1.1e-111
gi|119624348|gb|EAX03943.1| ring finger protein 8, ( 485) 2237 409.8 1.3e-111
gi|194223467|ref|XP_001500360.2| PREDICTED: simila ( 550) 2230 408.6 3.3e-111
gi|75061601|sp|Q5R4I2.1|RNF8_PONAB RecName: Full=E ( 486) 2209 404.8 4.1e-110
gi|119624350|gb|EAX03945.1| ring finger protein 8, ( 448) 1822 335.8 2.2e-89
gi|194390908|dbj|BAG60572.1| unnamed protein produ ( 417) 1815 334.5 5e-89
gi|118088051|ref|XP_419487.2| PREDICTED: hypotheti ( 523) 1669 308.6 4e-81
gi|8052306|emb|CAB92239.1| AIP37 protein [Mus musc ( 275) 1631 301.5 2.8e-79
gi|149549697|ref|XP_001511244.1| PREDICTED: simila ( 573) 1571 291.2 7.6e-76
gi|26339874|dbj|BAC33600.1| unnamed protein produc ( 837) 1471 273.5 2.3e-70
gi|74214476|dbj|BAE31091.1| unnamed protein produc ( 837) 1471 273.5 2.3e-70
gi|81906080|sp|Q9DBC3.1|FTSJ2_MOUSE RecName: Full= ( 837) 1471 273.5 2.3e-70
gi|74191719|dbj|BAE32821.1| unnamed protein produc ( 837) 1453 270.3 2.1e-69
gi|81883532|sp|Q5U2Z5.1|FTSJ2_RAT RecName: Full=Ft ( 837) 1453 270.3 2.1e-69
gi|45478098|gb|AAS66220.1| LRRG00129 [Rattus norve (1035) 1453 270.4 2.4e-69
gi|109070997|ref|XP_001117026.1| PREDICTED: simila ( 835) 1364 254.5 1.2e-64
gi|158258565|dbj|BAF85253.1| unnamed protein produ ( 835) 1364 254.5 1.2e-64
gi|126010617|gb|AAI33560.1| FTSJD2 protein [Bos ta ( 835) 1353 252.5 4.8e-64
gi|149549695|ref|XP_001511215.1| PREDICTED: simila ( 853) 1238 232.0 7.2e-58
gi|13365825|dbj|BAB39298.1| hypothetical protein [ ( 750) 1130 212.7 4.1e-52
gi|224047575|ref|XP_002187143.1| PREDICTED: hypoth ( 828) 1113 209.7 3.6e-51
gi|82184587|sp|Q6GQ76.1|FTSJ2_XENLA RecName: Full= ( 846) 1064 201.0 1.5e-48
gi|189442295|gb|AAI67621.1| LOC100170565 protein [ ( 503) 1036 195.8 3.5e-47
gi|56206049|emb|CAI19602.1| FtsJ methyltransferase ( 372) 1006 190.3 1.2e-45
gi|47224577|emb|CAG03561.1| unnamed protein produc ( 768) 964 183.2 3.3e-43
gi|82177092|sp|Q803R5.1|FTSJ2_DANRE RecName: Full= ( 829) 960 182.5 5.8e-43
gi|47123933|gb|AAH70792.1| Rnf8-b-prov protein [Xe ( 532) 910 173.4 2.1e-40
gi|28279440|gb|AAH46256.1| Rnf8-prov protein [Xeno ( 540) 877 167.5 1.2e-38
gi|194040435|ref|XP_001927703.1| PREDICTED: simila ( 179) 839 160.2 6.4e-37
gi|149043520|gb|EDL96971.1| ring finger protein 8, ( 126) 834 159.1 9.4e-37
gi|149269142|ref|XP_001479559.1| PREDICTED: simila ( 202) 786 150.8 4.8e-34
gi|195539833|gb|AAI68076.1| Unknown (protein for M ( 342) 787 151.2 6.1e-34
gi|210094783|gb|EEA42958.1| hypothetical protein B ( 584) 774 149.2 4.3e-33
gi|41351026|gb|AAH65643.1| Zgc:55936 [Danio rerio] ( 531) 769 148.2 7.5e-33
gi|27882568|gb|AAH44545.1| Zgc:55936 [Danio rerio] ( 485) 758 146.2 2.8e-32
gi|162329958|pdb|2PIE|A Chain A, Crystal Structure ( 138) 738 142.1 1.4e-31
gi|223648922|gb|ACN11219.1| E3 ubiquitin-protein l ( 475) 744 143.7 1.5e-31
gi|148690679|gb|EDL22626.1| ring finger protein 8 ( 146) 715 138.0 2.5e-30
gi|159163929|pdb|2CSW|A Chain A, Solution Structur ( 145) 713 137.6 3.2e-30
>>gi|73972753|ref|XP_864751.1| PREDICTED: similar to CG6 (880 aa)
initn: 3774 init1: 2755 opt: 3712 Z-score: 3577.4 bits: 672.9 E(): 1.5e-190
Smith-Waterman score: 3712; 78.779% identity (89.182% similar) in 721 aa overlap (31-743:1-720)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
: :: ::.:. :. : ::::: :. :::
gi|739 MEEPGSLVTGDRAGGRRWCLRRARMNAEWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: :.:::::::..:::::.::.:::::::.::::::: ::::::::::::::::::::
gi|739 LLEDGNEVTIGRGFGVTYQLVSKICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :.::::::::::::..:.::::::: ::::: . ::::::::: . :..:
gi|739 RLEPLKVYSIHKGDHIQLGVPLENKENAEYEYEVTEEDWERMYPCLAPKNDQIIGKNRGL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: ::. ::: : :. ...:. :: .: : ::::...:: : : ::::
gi|739 RTKRKFSLDELEGPGAEGPSHLKSKISKVSYKPGQPVKSHGKGEVASQPSEYLDPKLTSL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. ::.:. :. . ::. : ::::: :::::.:::::::::::.:::::::::::
gi|739 ELSEKATDAHVYPSSTKVVALH-HKKQKASSPSASQSSLELFKVTMSRILKLKTQMQEKQ
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
.:::::::::.::.:::::.:::::..::::: :::::::::::::::::::: ..::::
gi|739 VAVLNVKRQTQKGNSKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
::.::: ::::::.::::::.::::::: :::::: ::::::::::::::::.:.:::::
gi|739 EKDQGEEDLKQQLAQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
:::::.::.::::::::::::::::::::::::::::.:::::::::::::::::::.:.
gi|739 EVLSHVNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
:.::::::::.::::::::.::.:: ::::::.::::::::::::::::: ::.: :::
gi|739 THSLVLDNCINKMVDNLSSEVKDRRIVLIRERKASATSLSGSDSETEGKQHSSDSFDDAF
450 460 470 480 490 500
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
:::::::::::::::::::::.:::::::.:::::::::::::::::.::::::::::::
gi|739 KADSLVEGTSSRYSMYNSVSQKLMAKMGFKEGEGLGKYSQGRKDIVEASNQKGRRGLGLT
510 520 530 540 550 560
610 620 630 640 650 660
mKIAA0 LQGFDQELNVDWRDEPEPNACEQVSWFPECTTEIPDSREMSDWMVVGKRKMVIEDETEFC
::::::::::::::::::.:::::::::::::::::..:::::::.::::::::::::::
gi|739 LQGFDQELNVDWRDEPEPSACEQVSWFPECTTEIPDTQEMSDWMVMGKRKMVIEDETEFC
570 580 590 600 610 620
670 680 690 700 710 720
mKIAA0 GEELLHSMLKCKSVFDILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMF
:::::::.:.::::::.::::::::::::::::::::::::::::::::::::::::.::
gi|739 GEELLHSVLQCKSVFDVLDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDHMF
630 640 650 660 670 680
730 740
mKIAA0 TNPLDSSGA-----REASP---STCCGGRSGTQRALG
::: :: : ::: . :.: .:
gi|739 TNPRDSCGKPLVKDREAELLYFADVCAGPGGFSEYVLWRKKWHAKGFGMTLKGPNDFKLE
690 700 710 720 730 740
gi|739 DFYSASSELFEPYYGRDMKEEDGDITRPENITAFRNFVLDNTDRKGVHFLMADGGFSVEG
750 760 770 780 790 800
>>gi|73972755|ref|XP_538896.2| PREDICTED: similar to CG6 (1090 aa)
initn: 3774 init1: 2755 opt: 3712 Z-score: 3576.3 bits: 673.0 E(): 1.7e-190
Smith-Waterman score: 3712; 78.779% identity (89.182% similar) in 721 aa overlap (31-743:1-720)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
: :: ::.:. :. : ::::: :. :::
gi|739 MEEPGSLVTGDRAGGRRWCLRRARMNAEWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: :.:::::::..:::::.::.:::::::.::::::: ::::::::::::::::::::
gi|739 LLEDGNEVTIGRGFGVTYQLVSKICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :.::::::::::::..:.::::::: ::::: . ::::::::: . :..:
gi|739 RLEPLKVYSIHKGDHIQLGVPLENKENAEYEYEVTEEDWERMYPCLAPKNDQIIGKNRGL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: ::. ::: : :. ...:. :: .: : ::::...:: : : ::::
gi|739 RTKRKFSLDELEGPGAEGPSHLKSKISKVSYKPGQPVKSHGKGEVASQPSEYLDPKLTSL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. ::.:. :. . ::. : ::::: :::::.:::::::::::.:::::::::::
gi|739 ELSEKATDAHVYPSSTKVVALH-HKKQKASSPSASQSSLELFKVTMSRILKLKTQMQEKQ
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
.:::::::::.::.:::::.:::::..::::: :::::::::::::::::::: ..::::
gi|739 VAVLNVKRQTQKGNSKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
::.::: ::::::.::::::.::::::: :::::: ::::::::::::::::.:.:::::
gi|739 EKDQGEEDLKQQLAQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
:::::.::.::::::::::::::::::::::::::::.:::::::::::::::::::.:.
gi|739 EVLSHVNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
:.::::::::.::::::::.::.:: ::::::.::::::::::::::::: ::.: :::
gi|739 THSLVLDNCINKMVDNLSSEVKDRRIVLIRERKASATSLSGSDSETEGKQHSSDSFDDAF
450 460 470 480 490 500
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
:::::::::::::::::::::.:::::::.:::::::::::::::::.::::::::::::
gi|739 KADSLVEGTSSRYSMYNSVSQKLMAKMGFKEGEGLGKYSQGRKDIVEASNQKGRRGLGLT
510 520 530 540 550 560
610 620 630 640 650 660
mKIAA0 LQGFDQELNVDWRDEPEPNACEQVSWFPECTTEIPDSREMSDWMVVGKRKMVIEDETEFC
::::::::::::::::::.:::::::::::::::::..:::::::.::::::::::::::
gi|739 LQGFDQELNVDWRDEPEPSACEQVSWFPECTTEIPDTQEMSDWMVMGKRKMVIEDETEFC
570 580 590 600 610 620
670 680 690 700 710 720
mKIAA0 GEELLHSMLKCKSVFDILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMF
:::::::.:.::::::.::::::::::::::::::::::::::::::::::::::::.::
gi|739 GEELLHSVLQCKSVFDVLDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDHMF
630 640 650 660 670 680
730 740
mKIAA0 TNPLDSSGA-----REASP---STCCGGRSGTQRALG
::: :: : ::: . :.: .:
gi|739 TNPRDSCGKPLVKDREAELLYFADVCAGPGGFSEYVLWRKKWHAKGFGMTLKGPNDFKLE
690 700 710 720 730 740
gi|739 DFYSASSELFEPYYGEGGIDGDGDITRPENITAFRNFVLDNTDRKGVHFLMADGGFSVEG
750 760 770 780 790 800
>>gi|109070995|ref|XP_001117035.1| PREDICTED: similar to (1272 aa)
initn: 3643 init1: 2686 opt: 3586 Z-score: 3454.2 bits: 650.6 E(): 1.1e-183
Smith-Waterman score: 3586; 75.867% identity (87.656% similar) in 721 aa overlap (31-743:1-719)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
:::: .:.:. : :::::::.::. ::
gi|109 MGEPGFFVTGDRARGRSWCLRRVGMSAGWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: : :::.:::..:::::.::.:::::::.:::::::::::::::::::::::::::
gi|109 LLEDGREVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRA
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :..::.::::::::..:.::::::: :::::.. :::.::::: .::.:
gi|109 RLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKEL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: : . ::: :.:. . .:. . . : .:::...: : : ::.:
gi|109 RTKRKFSLDQLGGPGAEGPSNLKSKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTAL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. : ...: ..: : :. ..::: :::: ::..:::::::.:.:: :::::.
gi|109 EPSTKTTGAPIYPGFPIVTEVH--HEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKH
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
::.:::.::.::.::::::::.::..::::: :::::::::::::::::::: ..::::
gi|109 EAVMNVKKQTQKGNSKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
: ::: ::::::.:::::: ::::::: :::::: ::::::::::::::::.:::::::
gi|109 EIAQGEEDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::.::::::::::::::::::::::::::::.:::::::::.:::::::::::.
gi|109 EVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
: ::::::::.:::.::::.::::: ::::::.::.:::::::::::::: ::.: :::
gi|109 TYSLVLDNCINKMVNNLSSEVKERRIVLIRERKASTTSLSGSDSETEGKQHSSDSFDDAF
450 460 470 480 490 500
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
:::::::::::::::::::::.:::::::::::::::::::::::::.:.::::::::::
gi|109 KADSLVEGTSSRYSMYNSVSQKLMAKMGFREGEGLGKYSQGRKDIVEASSQKGRRGLGLT
510 520 530 540 550 560
610 620 630 640 650 660
mKIAA0 LQGFDQELNVDWRDEPEPNACEQVSWFPECTTEIPDSREMSDWMVVGKRKMVIEDETEFC
:.::::::::::::::::.:::::::::::::::::..:::::::::::::.::::::::
gi|109 LRGFDQELNVDWRDEPEPSACEQVSWFPECTTEIPDTQEMSDWMVVGKRKMIIEDETEFC
570 580 590 600 610 620
670 680 690 700 710 720
mKIAA0 GEELLHSMLKCKSVFDILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMF
:::::::.:.::::::.:::::::::::::::::::::::::::::::::::::::::::
gi|109 GEELLHSVLQCKSVFDVLDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMF
630 640 650 660 670 680
730 740
mKIAA0 TNPLDSSGA-----REASP---STCCGGRSGTQRALG
::: :: : ::: . :.: .:
gi|109 TNPRDSYGKPLVKDREAELLYFADVCAGPGGFSEYVLWRKKWHAKGFGMTLKGPNDFKLE
690 700 710 720 730 740
gi|109 DFYSASSELFEPYYGEGGIDGDGDITRPENISAFRNFVLDNTDRKGVHFLMADGGFSVEG
750 760 770 780 790 800
>>gi|21362895|sp|Q8VC56.1|RNF8_MOUSE RecName: Full=E3 ub (488 aa)
initn: 3340 init1: 3243 opt: 3243 Z-score: 3128.9 bits: 589.0 E(): 1.4e-165
Smith-Waterman score: 3243; 99.385% identity (99.590% similar) in 488 aa overlap (31-518:1-488)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
::::::::::::::::::::::::::::::
gi|213 MGEPDPLVSGQLAARRSWCLRRLGMDCEWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
220 230 240 250 260 270
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
280 290 300 310 320 330
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
340 350 360 370 380 390
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|213 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
400 410 420 430 440 450
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
::::::::::::::::::::::::::::::::::. :
gi|213 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRAKRLS
460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
>>gi|68534363|gb|AAH99079.1| Ring finger protein 8 [Ratt (487 aa)
initn: 1540 init1: 1518 opt: 2911 Z-score: 2809.2 bits: 529.8 E(): 9.1e-148
Smith-Waterman score: 2911; 90.289% identity (96.281% similar) in 484 aa overlap (31-514:1-483)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
:::::::::::::::::::::::::: :::
gi|685 MGEPDPLVSGQLAARRSWCLRRLGMDREWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:::::.:::::::.:::::::::::::::::.::::::::::::::::::::::::::::
gi|685 QLEAGSEVTIGRGFSVTYQLISKVCPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
::::::::::::::::::::::::.: ::::::::::: ::::::::::::. :::::
gi|685 RLAPLQGYCIRKGDHIQLGVPLESKEHAEYEYEVIEEDRESLAPCLAPKNDHTTEKHKGL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
:::::::: :.:.::::: ::::::::. .::: :::::::::.:.:: :::::: :.::
gi|685 RTKRKFSSDGVESLPAEGPSDLRCPLAKGSSKPAEPEKLHGKGEAASQPLGCLCPTLASL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
.::::.:::::::.::::::: ::::::: :::::.::::::.::::::::::::::::
gi|685 EASERTAGPHACSTLPKVLELY-PKKQKACSPSASQSSLELFKMTMSRMLKLKTQMQEKQ
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
:::::::::.:::::::.::::::::.:::::::::::::::::::::::::: ..::::
gi|685 IAVLNVKRQARKGSSKKVVRMEKELRDLQSQLYAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
:::::::::::::.::::::.::::::. :::::::::::::::::.:::::::::::::
gi|685 EKEQGECDLKQQLLQALQEHRALMEELDRSKKDFEKIIQAKNKELERTKEEKDKVQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::.:::::::::::::::::::::::::::::::.:::::::::::::::::::
gi|685 EVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSFCISEWMKRKVECPICRKDIESR
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
::::::::::::::. ::::::::::::::::::
gi|685 TNSLVLDNCISKMVERLSSDVKERRSVLIRERRAKRLL
450 460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
>>gi|73972751|ref|XP_864730.1| PREDICTED: similar to Ubi (487 aa)
initn: 2436 init1: 1411 opt: 2367 Z-score: 2285.3 bits: 432.9 E(): 1.4e-118
Smith-Waterman score: 2367; 75.000% identity (87.500% similar) in 488 aa overlap (31-518:1-487)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
: :: ::.:. :. : ::::: :. :::
gi|739 MEEPGSLVTGDRAGGRRWCLRRARMNAEWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: :.:::::::..:::::.::.:::::::.::::::: ::::::::::::::::::::
gi|739 LLEDGNEVTIGRGFGVTYQLVSKICPLMISRNHCVLKQNVEGQWTIMDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :.::::::::::::..:.::::::: ::::: . ::::::::: . :..:
gi|739 RLEPLKVYSIHKGDHIQLGVPLENKENAEYEYEVTEEDWERMYPCLAPKNDQIIGKNRGL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: ::. ::: : :. ...:. :: .: : ::::...:: : : ::::
gi|739 RTKRKFSLDELEGPGAEGPSHLKSKISKVSYKPGQPVKSHGKGEVASQPSEYLDPKLTSL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. ::.:. :. . ::. : ::::: :::::.:::::::::::.:::::::::::
gi|739 ELSEKATDAHVYPSSTKVVALH-HKKQKASSPSASQSSLELFKVTMSRILKLKTQMQEKQ
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
.:::::::::.::.:::::.:::::..::::: :::::::::::::::::::: ..::::
gi|739 VAVLNVKRQTQKGNSKKIVKMEKELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
::.::: ::::::.::::::.::::::: :::::: ::::::::::::::::.:.:::::
gi|739 EKDQGEEDLKQQLAQALQEHRALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
:::::.::.::::::::::::::::::::::::::::.:::::::::::::::::::.:.
gi|739 EVLSHVNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
:.::::::::.::::::::.::.:: ::::::.:. :
gi|739 THSLVLDNCINKMVDNLSSEVKDRRIVLIRERKAKRLS
450 460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
>>gi|119366657|sp|Q2HJ46.1|RNF8_BOVIN RecName: Full=E3 u (487 aa)
initn: 2401 init1: 1357 opt: 2308 Z-score: 2228.5 bits: 422.4 E(): 2e-115
Smith-Waterman score: 2308; 72.671% identity (87.992% similar) in 483 aa overlap (31-513:1-482)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
::.: ::. :..:::::::.::. :::
gi|119 MGDPGSLVTEGRAGERSWCLRRVGMNTEWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: :.:::.:::..:::::.::.:::::::.::.:::: :::::: :::::::::::::
gi|119 LLEDGNEVTVGRGFGVTYQLVSKICPLMISRNHCILKQNAEGQWTIKDNKSLNGVWLNRE
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :.::::::::::::..:.::::::: ::::: . :::.::.:: :::.::
gi|119 RLEPLKVYSIHKGDHIQLGVPLENKENAEYEYEVTEEDWERIYPCLSPKSDQMMEKNKGL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: ::. ::: :.:. ..... .: . : :::: ..:: : : :::.
gi|119 RTKRKFSLDELEGSGAEGPSNLKSKISKLSCEPGQQVKSHGKGKVASQPSEYLDPKLTSF
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. : ...: :. . ::.:: ::.:: :::::.:::::::::::.: :::::::::
gi|119 EPSVKTTGAHVNPGPAKVIEL-LRKKKKASNPSASQSSLELFKVTMSRILMLKTQMQEKQ
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
.::::::.::.::::::::.::.::..::::: ::::::::::::::::.::: ..:.::
gi|119 VAVLNVKKQTKKGSSKKIVKMEQELQDLQSQLCAEQAQQQARVEQLEKTIQEEQQHLEGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
:::.:: ::::::.:::::...:.:::: :::.:: :::::.::::::::::.:::::::
gi|119 EKEEGEEDLKQQLAQALQEYRSLVEELNRSKKNFEAIIQAKDKELEQTKEEKEKVQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::.::::::::::::::.:::::::::::::.:::::::::::::::::::.:.
gi|119 EVLSHMNDVLENELQCIICSEYFVEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
: :::::::::::::::.:.::::: ::::::.
gi|119 TRSLVLDNCISKMVDNLNSEVKERRIVLIRERKGKRLF
450 460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
>>gi|194040433|ref|XP_001927699.1| PREDICTED: similar to (512 aa)
initn: 2242 init1: 1407 opt: 2290 Z-score: 2210.9 bits: 419.2 E(): 1.9e-114
Smith-Waterman score: 2290; 74.059% identity (87.657% similar) in 478 aa overlap (37-514:34-508)
10 20 30 40 50 60
mKIAA0 TSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWLQLEAGT
::.: :. :::::::.::. ::. ::
gi|194 YDPEPKVSFSQILLAVITTQGRVGYGGARLLVTGGRAGDRSWCLRRVGMNAEWVLLE--E
10 20 30 40 50 60
70 80 90 100 110 120
mKIAA0 EVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRERLAPLQ
:::.:::..:::::.::.:::::::.::::::: :::::: ::::::::::::::: ::.
gi|194 EVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNAEGQWTITDNKSLNGVWLNRERLEPLK
70 80 90 100 110 120
130 140 150 160 170 180
mKIAA0 GYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGSRTKRKF
: :..:::::::::::..:.::::::: :.::: . :::. :.:: :::.:: ::::::
gi|194 VYSIHEGDHIQLGVPLENKENAEYEYEVTEDDWERVYPCLSLKSDQMMEKNKGLRTKRKF
130 140 150 160 170 180
190 200 210 220 230 240
mKIAA0 SSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSLKASERA
. ::. ::: : :. ...:. .: .: : : :: ...: : : :: :. : .:
gi|194 NLDELEGSGAEGPSTLKSKISKVSCEPGQPVKSHEKGKVAGQLNEYLDPKLTCLQPSGKA
190 200 210 220 230 240
250 260 270 280 290 300
mKIAA0 AGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQIAVLNV
: :. . ::.::. .:::: :::::.:::::::::::.:::::::::::::::::
gi|194 LGAHVYPVPAKVVELQ-HRKQKASNPSASQSSLELFKVTMSRILKLKTQMQEKQIAVLNV
250 260 270 280 290 300
310 320 330 340 350 360
mKIAA0 KRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGLEKEQGE
:.::.::.:::::.::.::..::::: :::::::::::::::::::: ..::::::::::
gi|194 KKQTQKGNSKKIVKMEQELHDLQSQLCAEQAQQQARVEQLEKTFQEEQQHLQGLEKEQGE
310 320 330 340 350 360
370 380 390 400 410 420
mKIAA0 CDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKEEVLSHM
::::::.::::::.::::::: :.:::: ::::::::::::::::.:::::::::::::
gi|194 EDLKQQLAQALQEHRALMEELNRSRKDFEAIIQAKNKELEQTKEEKEKVQAQKEEVLSHM
370 380 390 400 410 420
430 440 450 460 470 480
mKIAA0 NDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESRTNSLVL
::.::::::::::::::::::::::::::::.:::::::::::::::::::.:.:.::::
gi|194 NDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKVECPICRKDIKSKTHSLVL
430 440 450 460 470 480
490 500 510 520 530 540
mKIAA0 DNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAFKADSLV
::::.::::::::.::::: :::.::.:
gi|194 DNCINKMVDNLSSEVKERRVVLIKERKAKRLF
490 500 510
>>gi|90075162|dbj|BAE87261.1| unnamed protein product [M (486 aa)
initn: 2303 init1: 1344 opt: 2245 Z-score: 2167.9 bits: 411.2 E(): 4.8e-112
Smith-Waterman score: 2245; 71.281% identity (85.744% similar) in 484 aa overlap (31-514:1-482)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
:::: .:.:. : :::::::.::. ::
gi|900 MGEPGFFVTGDRARGRSWCLRRVGMSAGWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: : :::.:::..:::::.::.:::::::.:::::::::::::::::::::::::::
gi|900 LLEDGREVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRA
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :..::.::::::::..:.::::::: :::::.. :::.::::: .::.:
gi|900 RLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKEL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: : . ::: :.:. . .:. . . : .:::...: : : ::.:
gi|900 RTKRKFSLDQLGGPGAEGPSNLKSKINKVSCESSQSVKSQGKGEVASTPSENLDPKLTAL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. :....: ..: : :. ..::: :::: ::..:::::::.:.:: :::::.
gi|900 EPSKKTTGAPIYPGFPIVTEVH--HEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKH
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
::.:::.::.::.::::::::.::..::::: :::::::::::::::::::: ..::::
gi|900 EAVMNVKKQTQKGNSKKIVRMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
: ::: ::::::.:::::: ::::::: :::::: ::::::::::::::::.:::::::
gi|900 EIAQGEEDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKVQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::.::::::::::::::::::::::::::::.:::::::::.:::::::::::.
gi|900 EVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIESK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
: ::::::::.:::.::::.::::: ::::::.:
gi|900 TYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
450 460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
>>gi|21362894|sp|O76064.1|RNF8_HUMAN RecName: Full=E3 ub (485 aa)
initn: 2278 init1: 1328 opt: 2242 Z-score: 2165.0 bits: 410.6 E(): 7e-112
Smith-Waterman score: 2242; 70.868% identity (86.364% similar) in 484 aa overlap (31-514:1-481)
10 20 30 40 50 60
mKIAA0 LSCARGTSEAAGAQARGWLVAERCPSADRAMGEPDPLVSGQLAARRSWCLRRLGMDCEWL
:::: .:.:. :. :::::::.::. ::
gi|213 MGEPGFFVTGDRAGGRSWCLRRVGMSAGWL
10 20 30
70 80 90 100 110 120
mKIAA0 QLEAGTEVTIGRGLSVTYQLISKVCPLMISRSHCVLKQNPEGQWTIMDNKSLNGVWLNRE
:: : :::.:::..:::::.::.:::::::.:::::::::::::::::::::::::::
gi|213 LLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRA
40 50 60 70 80 90
130 140 150 160 170 180
mKIAA0 RLAPLQGYCIRKGDHIQLGVPLESRETAEYEYEVIEEDWESLAPCLAPKNDQRMEKHKGS
:: ::. : :..::.::::::::..:.::::::: :::::.. :::.::::: .::.:
gi|213 RLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKNDQMIEKNKEL
100 110 120 130 140 150
190 200 210 220 230 240
mKIAA0 RTKRKFSSPGLENLPAEGSSDLRCPLANVASKPIEPEKLHGKGDASSQSLGCLCPGLTSL
::::::: : . ::: :.:. . .:. . .: : .:::...: : : ::.:
gi|213 RTKRKFSLDELAGPGAEGPSNLKSKINKVSCESGQPVKSQGKGEVASTPSDNLDPKLTAL
160 170 180 190 200 210
250 260 270 280 290 300
mKIAA0 KASERAAGPHACSALPKVLELSCPKKQKACRPSASQNSLELFKVTMSRMLKLKTQMQEKQ
. :. ...: ..::: :. ..::: :::: ::..:::::::.:.:: :::::.
gi|213 EPSKTTGAP-IYPGFPKVTEVH--HEQKASNSSASQRSLQMFKVTMSRILRLKIQMQEKH
220 230 240 250 260
310 320 330 340 350 360
mKIAA0 IAVLNVKRQTRKGSSKKIVRMEKELRNLQSQLYAEQAQQQARVEQLEKTFQEEAHYLQGL
::.:::.::.::.:::.:.::.::..::::: :::::::::::::::::::: ..::::
gi|213 EAVMNVKKQTQKGNSKKVVQMEQELQDLQSQLCAEQAQQQARVEQLEKTFQEEEQHLQGL
270 280 290 300 310 320
370 380 390 400 410 420
mKIAA0 EKEQGECDLKQQLVQALQEHQALMEELNCSKKDFEKIIQAKNKELEQTKEEKDKVQAQKE
: ::: ::::::.:::::: ::::::: :::::: ::::::::::::::::.:.:::::
gi|213 EIAQGEKDLKQQLAQALQEHWALMEELNRSKKDFEAIIQAKNKELEQTKEEKEKMQAQKE
330 340 350 360 370 380
430 440 450 460 470 480
mKIAA0 EVLSHMNDLLENELQCIICSEYFIEAVTLNCAHSFCSFCINEWMKRKVECPICRKDIESR
::::::::.::::::::::::::::::::::::::::.:::::::::.:::::::::.:.
gi|213 EVLSHMNDVLENELQCIICSEYFIEAVTLNCAHSFCSYCINEWMKRKIECPICRKDIKSK
390 400 410 420 430 440
490 500 510 520 530 540
mKIAA0 TNSLVLDNCISKMVDNLSSDVKERRSVLIRERRASATSLSGSDSETEGKQPCSDDFKDAF
: ::::::::.:::.::::.::::: ::::::.:
gi|213 TYSLVLDNCINKMVNNLSSEVKERRIVLIRERKAKRLF
450 460 470 480
550 560 570 580 590 600
mKIAA0 KADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLT
749 residues in 1 query sequences
2727779818 residues in 7921681 library sequences
Tcomplib [34.26] (2 proc)
start: Sun Mar 15 16:46:33 2009 done: Sun Mar 15 16:54:36 2009
Total Scan time: 1065.240 Total Display time: 0.220
Function used was FASTA [version 34.26.5 April 26, 2007]