# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mpf00742.fasta.nr -Q ../query/mKIAA1481.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
mKIAA1481, 1726 aa
vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library
2727779818 residues in 7921681 sequences
statistics sampled from 60000 to 7905444 sequences
Expectation_n fit: rho(ln(x))= 6.6498+/-0.00021; mu= 10.3118+/- 0.012
mean_var=157.8251+/-29.893, 0's: 33 Z-trim: 72 B-trim: 0 in 0/65
Lambda= 0.102091
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 41, opt: 29, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7921681)
gi|148673289|gb|EDL05236.1| shroom family member 3 (1980) 11672 1732.7 0
gi|74184685|dbj|BAE27948.1| unnamed protein produc (1805) 11661 1731.0 0
gi|117606395|ref|NP_056571.2| shroom isoform 1 [Mu (1980) 11661 1731.1 0
gi|146325726|sp|Q9QXN0.2|SHRM3_MOUSE RecName: Full (1986) 11644 1728.6 0
gi|6467992|gb|AAF13270.1|AF199422_1 actin binding (1811) 11400 1692.6 0
gi|6467990|gb|AAF13269.1|AF199421_1 PDZ domain act (1986) 11400 1692.6 0
gi|149033855|gb|EDL88651.1| similar to PDZ domain (1987) 9800 1457.0 0
gi|109499527|ref|XP_223229.4| PREDICTED: similar t (1986) 7194 1073.2 0
gi|219519297|gb|AAI45114.1| Unknown (protein for M (1849) 6374 952.4 0
gi|126330937|ref|XP_001363590.1| PREDICTED: simila (1889) 4389 660.0 5.4e-186
gi|194385258|dbj|BAG65006.1| unnamed protein produ (1124) 4015 604.7 1.5e-169
gi|193785922|dbj|BAG54709.1| unnamed protein produ (1774) 3395 513.6 6.1e-142
gi|162318472|gb|AAI56133.1| Shroom family member 3 (1995) 3395 513.6 6.6e-142
gi|203098098|ref|NP_065910.3| shroom family member (1996) 3395 513.6 6.6e-142
gi|74716122|sp|Q8TF72.1|SHRM3_HUMAN RecName: Full= (1995) 3389 512.7 1.2e-141
gi|119626200|gb|EAX05795.1| shroom, isoform CRA_b (1996) 3389 512.7 1.2e-141
gi|13278127|gb|AAH03909.1| Shroom3 protein [Mus mu ( 481) 3137 475.0 6.9e-131
gi|34530195|dbj|BAC85848.1| unnamed protein produc ( 809) 2918 442.9 5e-121
gi|109074409|ref|XP_001094662.1| PREDICTED: simila (1780) 2881 437.9 3.8e-119
gi|109074407|ref|XP_001094783.1| PREDICTED: simila (2001) 2881 437.9 4.1e-119
gi|13938323|gb|AAH07291.1| SHROOM3 protein [Homo s ( 767) 2810 427.0 3e-116
gi|74001898|ref|XP_850003.1| PREDICTED: similar to (2151) 2686 409.2 1.9e-110
gi|224049105|ref|XP_002193053.1| PREDICTED: simila (1841) 1839 284.4 6.1e-73
gi|123891714|sp|Q27IV2.1|SHRM3_XENLA RecName: Full (1788) 1731 268.5 3.7e-68
gi|60688655|gb|AAH91437.1| Shroom3 protein [Rattus ( 263) 1588 246.5 2.2e-62
gi|118090256|ref|XP_420592.2| PREDICTED: similar t (2026) 1585 247.0 1.2e-61
gi|47213455|emb|CAF95451.1| unnamed protein produc (1578) 1189 188.6 3.6e-44
gi|1773381|gb|AAC32592.1| APXL [Homo sapiens] (1561) 1184 187.9 6e-44
gi|2498147|sp|Q13796.1|SHRM2_HUMAN RecName: Full=P (1616) 1184 187.9 6.1e-44
gi|119619180|gb|EAW98774.1| apical protein-like (X (1616) 1180 187.3 9.2e-44
gi|194227661|ref|XP_001488443.2| PREDICTED: simila (1538) 1121 178.6 3.7e-41
gi|224042802|ref|XP_002188877.1| PREDICTED: shroom (1649) 1121 178.6 3.9e-41
gi|158508586|ref|NP_001041358.2| shroom family mem (1491) 1113 177.4 8.2e-41
gi|123884799|sp|Q09JY9.1|SHRM2_XENTR RecName: Full (1726) 1112 177.3 1e-40
gi|221042982|dbj|BAH13168.1| unnamed protein produ ( 451) 1101 175.1 1.2e-40
gi|148699423|gb|EDL31370.1| mCG14480, isoform CRA_ (1459) 1103 175.9 2.2e-40
gi|26340590|dbj|BAC33957.1| unnamed protein produc ( 446) 1095 174.2 2.3e-40
gi|26325300|dbj|BAC26404.1| unnamed protein produc ( 495) 1095 174.2 2.4e-40
gi|26328081|dbj|BAC27781.1| unnamed protein produc ( 495) 1095 174.2 2.4e-40
gi|74007103|ref|XP_548854.2| PREDICTED: similar to (1630) 1102 175.8 2.7e-40
gi|146325725|sp|A2ALU4.1|SHRM2_MOUSE RecName: Full (1481) 1097 175.0 4.2e-40
gi|126360808|gb|ABO09922.1| SHROOM2 [Mus musculus] (1487) 1095 174.7 5.1e-40
gi|51476274|emb|CAH18127.1| hypothetical protein [ ( 450) 1084 172.6 7e-40
gi|87083916|gb|ABD19518.1| Apxl protein [Mus muscu (1480) 1081 172.7 2.1e-39
gi|189525601|ref|XP_684470.3| PREDICTED: similar t (1464) 1075 171.8 3.9e-39
gi|194687125|ref|XP_001256796.2| PREDICTED: simila ( 436) 1031 164.7 1.5e-37
gi|189520270|ref|XP_700005.3| PREDICTED: similar t (1657) 1016 163.1 1.8e-36
gi|81865305|sp|Q7TP36.1|SHRM2_RAT RecName: Full=Pr (1423) 915 148.2 4.8e-32
gi|118084187|ref|XP_416847.2| PREDICTED: similar t (1669) 913 148.0 6.5e-32
gi|33337757|gb|AAQ13515.1|AF109367_1 MSTP013 [Homo ( 161) 894 144.1 9.2e-32
>>gi|148673289|gb|EDL05236.1| shroom family member 3 [Mu (1980 aa)
initn: 11672 init1: 11672 opt: 11672 Z-score: 9292.5 bits: 1732.7 E(): 0
Smith-Waterman score: 11672; 99.594% identity (99.826% similar) in 1726 aa overlap (1-1726:255-1980)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|148 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
470 480 490 500 510 520
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
530 540 550 560 570 580
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
590 600 610 620 630 640
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
650 660 670 680 690 700
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
710 720 730 740 750 760
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
770 780 790 800 810 820
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
830 840 850 860 870 880
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
890 900 910 920 930 940
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
950 960 970 980 990 1000
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
1010 1020 1030 1040 1050 1060
820 830 840 850 860 870
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
1070 1080 1090 1100 1110 1120
880 890 900 910 920 930
mKIAA1 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
1130 1140 1150 1160 1170 1180
940 950 960 970 980 990
mKIAA1 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
1190 1200 1210 1220 1230 1240
1000 1010 1020 1030 1040 1050
mKIAA1 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
1250 1260 1270 1280 1290 1300
1060 1070 1080 1090 1100 1110
mKIAA1 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|148 TVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
1310 1320 1330 1340 1350 1360
1120 1130 1140 1150 1160 1170
mKIAA1 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLWVKWAHA
:::::::::::::::::::::::::::::::::::: .::::::::::.::: :::::::
gi|148 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLGEGMWKRTSLPQRPPPPWVKWAHA
1370 1380 1390 1400 1410 1420
1180 1190 1200 1210 1220 1230
mKIAA1 VREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
gi|148 VREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
1430 1440 1450 1460 1470 1480
1240 1250 1260 1270 1280 1290
mKIAA1 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
1490 1500 1510 1520 1530 1540
1300 1310 1320 1330 1340 1350
mKIAA1 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
1550 1560 1570 1580 1590 1600
1360 1370 1380 1390 1400 1410
mKIAA1 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
1610 1620 1630 1640 1650 1660
1420 1430 1440 1450 1460 1470
mKIAA1 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
1670 1680 1690 1700 1710 1720
1480 1490 1500 1510 1520 1530
mKIAA1 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
1730 1740 1750 1760 1770 1780
1540 1550 1560 1570 1580 1590
mKIAA1 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
1790 1800 1810 1820 1830 1840
1600 1610 1620 1630 1640 1650
mKIAA1 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
1850 1860 1870 1880 1890 1900
1660 1670 1680 1690 1700 1710
mKIAA1 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHATPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|148 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHGTPG
1910 1920 1930 1940 1950 1960
1720
mKIAA1 GTSVFGGVFPTLTSPL
::::::::::::::::
gi|148 GTSVFGGVFPTLTSPL
1970 1980
>>gi|74184685|dbj|BAE27948.1| unnamed protein product [M (1805 aa)
initn: 11661 init1: 11661 opt: 11661 Z-score: 9284.2 bits: 1731.0 E(): 0
Smith-Waterman score: 11661; 99.536% identity (99.768% similar) in 1726 aa overlap (1-1726:80-1805)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|741 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
50 60 70 80 90 100
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
110 120 130 140 150 160
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
170 180 190 200 210 220
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
230 240 250 260 270 280
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
290 300 310 320 330 340
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
350 360 370 380 390 400
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
410 420 430 440 450 460
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
gi|741 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAQEVHPGGRSKVEDPGRKAGASD
470 480 490 500 510 520
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
530 540 550 560 570 580
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
590 600 610 620 630 640
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
650 660 670 680 690 700
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
710 720 730 740 750 760
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
770 780 790 800 810 820
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
830 840 850 860 870 880
820 830 840 850 860 870
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
890 900 910 920 930 940
880 890 900 910 920 930
mKIAA1 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
950 960 970 980 990 1000
940 950 960 970 980 990
mKIAA1 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
1010 1020 1030 1040 1050 1060
1000 1010 1020 1030 1040 1050
mKIAA1 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
1070 1080 1090 1100 1110 1120
1060 1070 1080 1090 1100 1110
mKIAA1 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|741 TVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
1130 1140 1150 1160 1170 1180
1120 1130 1140 1150 1160 1170
mKIAA1 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLWVKWAHA
:::::::::::::::::::::::::::::::::::: .::::::::::.::: :::::::
gi|741 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLGEGMWKRTSLPQRPPPPWVKWAHA
1190 1200 1210 1220 1230 1240
1180 1190 1200 1210 1220 1230
mKIAA1 VREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
gi|741 VREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
1250 1260 1270 1280 1290 1300
1240 1250 1260 1270 1280 1290
mKIAA1 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
1310 1320 1330 1340 1350 1360
1300 1310 1320 1330 1340 1350
mKIAA1 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
1370 1380 1390 1400 1410 1420
1360 1370 1380 1390 1400 1410
mKIAA1 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
1430 1440 1450 1460 1470 1480
1420 1430 1440 1450 1460 1470
mKIAA1 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
1490 1500 1510 1520 1530 1540
1480 1490 1500 1510 1520 1530
mKIAA1 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
1550 1560 1570 1580 1590 1600
1540 1550 1560 1570 1580 1590
mKIAA1 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
1610 1620 1630 1640 1650 1660
1600 1610 1620 1630 1640 1650
mKIAA1 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
1670 1680 1690 1700 1710 1720
1660 1670 1680 1690 1700 1710
mKIAA1 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHATPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|741 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHGTPG
1730 1740 1750 1760 1770 1780
1720
mKIAA1 GTSVFGGVFPTLTSPL
::::::::::::::::
gi|741 GTSVFGGVFPTLTSPL
1790 1800
>>gi|117606395|ref|NP_056571.2| shroom isoform 1 [Mus mu (1980 aa)
initn: 11661 init1: 11661 opt: 11661 Z-score: 9283.7 bits: 1731.1 E(): 0
Smith-Waterman score: 11661; 99.536% identity (99.768% similar) in 1726 aa overlap (1-1726:255-1980)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|117 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
470 480 490 500 510 520
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
530 540 550 560 570 580
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
590 600 610 620 630 640
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
gi|117 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAQEVHPGGRSKVEDPGRKAGASD
650 660 670 680 690 700
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
710 720 730 740 750 760
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
770 780 790 800 810 820
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
830 840 850 860 870 880
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
890 900 910 920 930 940
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
950 960 970 980 990 1000
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
1010 1020 1030 1040 1050 1060
820 830 840 850 860 870
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
1070 1080 1090 1100 1110 1120
880 890 900 910 920 930
mKIAA1 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
1130 1140 1150 1160 1170 1180
940 950 960 970 980 990
mKIAA1 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
1190 1200 1210 1220 1230 1240
1000 1010 1020 1030 1040 1050
mKIAA1 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
1250 1260 1270 1280 1290 1300
1060 1070 1080 1090 1100 1110
mKIAA1 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
:::::::::::::.::::::::::::::::::::::::::::::::::::::::::::::
gi|117 TVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
1310 1320 1330 1340 1350 1360
1120 1130 1140 1150 1160 1170
mKIAA1 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLWVKWAHA
:::::::::::::::::::::::::::::::::::: .::::::::::.::: :::::::
gi|117 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLGEGMWKRTSLPQRPPPPWVKWAHA
1370 1380 1390 1400 1410 1420
1180 1190 1200 1210 1220 1230
mKIAA1 VREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
:::::::::::::::::::::::::: :::::::::::::::::::::::::::::::::
gi|117 VREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
1430 1440 1450 1460 1470 1480
1240 1250 1260 1270 1280 1290
mKIAA1 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
1490 1500 1510 1520 1530 1540
1300 1310 1320 1330 1340 1350
mKIAA1 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
1550 1560 1570 1580 1590 1600
1360 1370 1380 1390 1400 1410
mKIAA1 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
1610 1620 1630 1640 1650 1660
1420 1430 1440 1450 1460 1470
mKIAA1 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
1670 1680 1690 1700 1710 1720
1480 1490 1500 1510 1520 1530
mKIAA1 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
1730 1740 1750 1760 1770 1780
1540 1550 1560 1570 1580 1590
mKIAA1 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
1790 1800 1810 1820 1830 1840
1600 1610 1620 1630 1640 1650
mKIAA1 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|117 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
1850 1860 1870 1880 1890 1900
1660 1670 1680 1690 1700 1710
mKIAA1 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHATPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
gi|117 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHGTPG
1910 1920 1930 1940 1950 1960
1720
mKIAA1 GTSVFGGVFPTLTSPL
::::::::::::::::
gi|117 GTSVFGGVFPTLTSPL
1970 1980
>>gi|146325726|sp|Q9QXN0.2|SHRM3_MOUSE RecName: Full=Pro (1986 aa)
initn: 7669 init1: 7582 opt: 11644 Z-score: 9270.2 bits: 1728.6 E(): 0
Smith-Waterman score: 11644; 99.249% identity (99.423% similar) in 1732 aa overlap (1-1726:255-1986)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|146 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
470 480 490 500 510 520
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
530 540 550 560 570 580
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
590 600 610 620 630 640
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
gi|146 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAQEVHPGGRSKVEDPGRKAGASD
650 660 670 680 690 700
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
710 720 730 740 750 760
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
770 780 790 800 810 820
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
830 840 850 860 870 880
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
890 900 910 920 930 940
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
950 960 970 980 990 1000
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
1010 1020 1030 1040 1050 1060
820 830 840 850 860 870
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
1070 1080 1090 1100 1110 1120
880 890 900 910 920 930
mKIAA1 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
1130 1140 1150 1160 1170 1180
940 950 960 970 980 990
mKIAA1 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
1190 1200 1210 1220 1230 1240
1000 1010 1020 1030 1040 1050
mKIAA1 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
1250 1260 1270 1280 1290 1300
1060 1070 1080 1090 1100
mKIAA1 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPS------
:::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|146 TVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSASPVPS
1310 1320 1330 1340 1350 1360
1110 1120 1130 1140 1150 1160
mKIAA1 SYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLW
:::::::::::::::::::::::::::::::::::::::::: .::::::::::.::: :
gi|146 SYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLGEGMWKRTSLPQRPPPPW
1370 1380 1390 1400 1410 1420
1170 1180 1190 1200 1210 1220
mKIAA1 VKWAHAVREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPS
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
gi|146 VKWAHAVREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQPS
1430 1440 1450 1460 1470 1480
1230 1240 1250 1260 1270 1280
mKIAA1 PPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 PPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALC
1490 1500 1510 1520 1530 1540
1290 1300 1310 1320 1330 1340
mKIAA1 EVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 EVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNT
1550 1560 1570 1580 1590 1600
1350 1360 1370 1380 1390 1400
mKIAA1 PSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 PSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKE
1610 1620 1630 1640 1650 1660
1410 1420 1430 1440 1450 1460
mKIAA1 IVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 IVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKAS
1670 1680 1690 1700 1710 1720
1470 1480 1490 1500 1510 1520
mKIAA1 DHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 DHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKL
1730 1740 1750 1760 1770 1780
1530 1540 1550 1560 1570 1580
mKIAA1 ESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 ESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGR
1790 1800 1810 1820 1830 1840
1590 1600 1610 1620 1630 1640
mKIAA1 LARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 LARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLS
1850 1860 1870 1880 1890 1900
1650 1660 1670 1680 1690 1700
mKIAA1 AEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|146 AEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALT
1910 1920 1930 1940 1950 1960
1710 1720
mKIAA1 GHATPGGTSVFGGVFPTLTSPL
::::::::::::::::::::::
gi|146 GHATPGGTSVFGGVFPTLTSPL
1970 1980
>>gi|6467992|gb|AAF13270.1|AF199422_1 actin binding prot (1811 aa)
initn: 7416 init1: 7329 opt: 11400 Z-score: 9076.5 bits: 1692.6 E(): 0
Smith-Waterman score: 11400; 97.576% identity (98.269% similar) in 1733 aa overlap (1-1726:80-1811)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|646 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
50 60 70 80 90 100
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
110 120 130 140 150 160
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
170 180 190 200 210 220
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SSLDHKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
230 240 250 260 270 280
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
290 300 310 320 330 340
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
350 360 370 380 390 400
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
gi|646 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRKPSRLSQPWEGDFQEDHNANLRQKVERE
410 420 430 440 450 460
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
gi|646 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAQEVHPGGRSKVEDPGRKAGASD
470 480 490 500 510 520
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
530 540 550 560 570 580
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
gi|646 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGNRPGRTGPTPSTSSSDLDDPKAGSV
590 600 610 620 630 640
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
650 660 670 680 690 700
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
710 720 730 740 750 760
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
770 780 790 800 810 820
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
830 840 850 860 870 880
820 830 840 850 860
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAG-PAAPDGPG
:::::::::::::.:::::::::::::::::: . .: ::.. : : : . :
gi|646 LSLSGPELKQFQQNALADYIQRKTGKRPTGAA-SHTGGRAARARTERLPPGRPRGARWPR
890 900 910 920 930 940
870 880 890 900 910 920
mKIAA1 LASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQL
950 960 970 980 990 1000
930 940 950 960 970 980
mKIAA1 LSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
gi|646 LSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSKSSPT
1010 1020 1030 1040 1050 1060
990 1000 1010 1020 1030 1040
mKIAA1 SDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCK
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
gi|646 SDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHHTPCWNGSGCK
1070 1080 1090 1100 1110 1120
1050 1060 1070 1080 1090 1100
mKIAA1 ATVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPS-----
::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|646 ATVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSASPVP
1130 1140 1150 1160 1170 1180
1110 1120 1130 1140 1150 1160
mKIAA1 -SYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPL
:::::::::::::::::::::::::::::::: ::::::::: .::::::::::.:::
gi|646 SSYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSLELSSPAYGLGEGMWKRTSLPQRPPPP
1190 1200 1210 1220 1230 1240
1170 1180 1190 1200 1210 1220
mKIAA1 WVKWAHAVREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQP
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
gi|646 WVKWAHAVREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQP
1250 1260 1270 1280 1290 1300
1230 1240 1250 1260 1270 1280
mKIAA1 SPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQAL
1310 1320 1330 1340 1350 1360
1290 1300 1310 1320 1330 1340
mKIAA1 CEVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 CEVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESN
1370 1380 1390 1400 1410 1420
1350 1360 1370 1380 1390 1400
mKIAA1 TPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAK
1430 1440 1450 1460 1470 1480
1410 1420 1430 1440 1450 1460
mKIAA1 EIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 EIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKA
1490 1500 1510 1520 1530 1540
1470 1480 1490 1500 1510 1520
mKIAA1 SDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHK
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
gi|646 SDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVYEKKAELIGSLTHK
1550 1560 1570 1580 1590 1600
1530 1540 1550 1560 1570 1580
mKIAA1 LESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSG
1610 1620 1630 1640 1650 1660
1590 1600 1610 1620 1630 1640
mKIAA1 RLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYL
1670 1680 1690 1700 1710 1720
1650 1660 1670 1680 1690 1700
mKIAA1 SAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPAL
1730 1740 1750 1760 1770 1780
1710 1720
mKIAA1 TGHATPGGTSVFGGVFPTLTSPL
:::::::::::::::::::::::
gi|646 TGHATPGGTSVFGGVFPTLTSPL
1790 1800 1810
>>gi|6467990|gb|AAF13269.1|AF199421_1 PDZ domain actin b (1986 aa)
initn: 7416 init1: 7329 opt: 11400 Z-score: 9076.0 bits: 1692.6 E(): 0
Smith-Waterman score: 11400; 97.576% identity (98.269% similar) in 1733 aa overlap (1-1726:255-1986)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|646 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SSLDHKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
470 480 490 500 510 520
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
530 540 550 560 570 580
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
gi|646 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRKPSRLSQPWEGDFQEDHNANLRQKVERE
590 600 610 620 630 640
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
:::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::
gi|646 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAQEVHPGGRSKVEDPGRKAGASD
650 660 670 680 690 700
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
710 720 730 740 750 760
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
gi|646 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGNRPGRTGPTPSTSSSDLDDPKAGSV
770 780 790 800 810 820
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
830 840 850 860 870 880
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
890 900 910 920 930 940
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
950 960 970 980 990 1000
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
1010 1020 1030 1040 1050 1060
820 830 840 850 860
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAG-PAAPDGPG
:::::::::::::.:::::::::::::::::: . .: ::.. : : : . :
gi|646 LSLSGPELKQFQQNALADYIQRKTGKRPTGAA-SHTGGRAARARTERLPPGRPRGARWPR
1070 1080 1090 1100 1110 1120
870 880 890 900 910 920
mKIAA1 LASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQL
1130 1140 1150 1160 1170 1180
930 940 950 960 970 980
mKIAA1 LSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
gi|646 LSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSKSSPT
1190 1200 1210 1220 1230 1240
990 1000 1010 1020 1030 1040
mKIAA1 SDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCK
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
gi|646 SDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHHTPCWNGSGCK
1250 1260 1270 1280 1290 1300
1050 1060 1070 1080 1090 1100
mKIAA1 ATVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPS-----
::::::::::::::.::::::::::::::::::::::::::::::::::::::::
gi|646 ATVASSAPPESSGAADHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSASPVP
1310 1320 1330 1340 1350 1360
1110 1120 1130 1140 1150 1160
mKIAA1 -SYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPL
:::::::::::::::::::::::::::::::: ::::::::: .::::::::::.:::
gi|646 SSYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSLELSSPAYGLGEGMWKRTSLPQRPPPP
1370 1380 1390 1400 1410 1420
1170 1180 1190 1200 1210 1220
mKIAA1 WVKWAHAVREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQP
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
gi|646 WVKWAHAVREDGLAEDTLAPEFANLKHYRNQPSRPSSCSTSDPDTPGRISLRISESALQP
1430 1440 1450 1460 1470 1480
1230 1240 1250 1260 1270 1280
mKIAA1 SPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQAL
1490 1500 1510 1520 1530 1540
1290 1300 1310 1320 1330 1340
mKIAA1 CEVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 CEVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESN
1550 1560 1570 1580 1590 1600
1350 1360 1370 1380 1390 1400
mKIAA1 TPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 TPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAK
1610 1620 1630 1640 1650 1660
1410 1420 1430 1440 1450 1460
mKIAA1 EIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 EIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKA
1670 1680 1690 1700 1710 1720
1470 1480 1490 1500 1510 1520
mKIAA1 SDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHK
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
gi|646 SDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVYEKKAELIGSLTHK
1730 1740 1750 1760 1770 1780
1530 1540 1550 1560 1570 1580
mKIAA1 LESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 LESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSG
1790 1800 1810 1820 1830 1840
1590 1600 1610 1620 1630 1640
mKIAA1 RLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 RLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYL
1850 1860 1870 1880 1890 1900
1650 1660 1670 1680 1690 1700
mKIAA1 SAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|646 SAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPAL
1910 1920 1930 1940 1950 1960
1710 1720
mKIAA1 TGHATPGGTSVFGGVFPTLTSPL
:::::::::::::::::::::::
gi|646 TGHATPGGTSVFGGVFPTLTSPL
1970 1980
>>gi|149033855|gb|EDL88651.1| similar to PDZ domain acti (1987 aa)
initn: 5207 init1: 2222 opt: 9800 Z-score: 7802.4 bits: 1457.0 E(): 0
Smith-Waterman score: 9800; 85.306% identity (91.995% similar) in 1749 aa overlap (1-1726:255-1987)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|149 LGPRGGSPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
:.:.: ::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|149 SLDMIPARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHTSADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::: :::::::: ::: :: :.:::::.::::::::.:.:::::::::
gi|149 AKWHSIPRGKGTPPLPWSQQCSGSPETA-DNPPHKAGAPMPPTRSDSYVALRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::: :::::::.:.::::::::::::::::: :::::::.::::::::
gi|149 SSLDQKRFCRPQTNSLGSQKTPFVEEQLHTVPERSPENSPPVKPKHNYTQKTQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::.:::::::::::::::::::::.:::.:::::::.:.:
gi|149 TGIYPVPSPEPHFAQVPQPSVSGNGTVYPALVKESGYTAAQGTCSKMAALDENGNQKEVS
470 480 490 500 510 520
280 290 300 310 320
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYI-YKVHFSSVPENEDSSLKRHITPPHGHSPYP
::::::::: ::.:.:::::.::: :::: :::::::::::::::::::.:::::.: ::
gi|149 RPGFAFCQPPEHDSMTPVEKKPEPRAKYIPYKVHFSSVPENEDSSLKRHVTPPHGNSLYP
530 540 550 560 570 580
330 340 350 360 370 380
mKIAA1 SERKNIHGG-SRACSNHHSLSSPQAQALHVGDD-RRPSRLSQPWEGDFQEDHNANLRQKV
:::::.::: :: ::::::: : :::: :.::: :::::: :::::::::::::::::::
gi|149 SERKNVHGGGSRPCSNHHSLPSAQAQAPHAGDDDRRPSRLFQPWEGDFQEDHNANLRQKV
590 600 610 620 630 640
390 400 410 420 430 440
mKIAA1 EREGQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRS-------KVE
::::::::: :::: :.:.:: ::::::.:::::.:.:::. ::.::::: :::
gi|149 EREGQGQGLPGNSGGTKSTFSPLQNIPENLRRQSSVDLGEGLEVYPGGRSTCATTTTKVE
650 660 670 680 690 700
450 460 470 480 490
mKIAA1 DPGRKAGASDIRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQ-TSGASQRR
::::::: : :::::::::::::::::::..: ::::::::: : : :: ::: ::::
gi|149 DPGRKAGP-DNRGYLDRSVSYPRPEGKMNAAESFHSADSRYEE-PLAAPPQQTSGMSQRR
710 720 730 740 750 760
500 510 520 530 540 550
mKIAA1 LSSSSSAAPQYRKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSS
::.::. : ::.:::::::::::.::::::::::: :::::::. .::::::::::::::
gi|149 LSASSTPALQYKKPHCSVLEKVSKIEEREQGRHRPTSVGSSAYALSYRPGRTGPTPSTSS
770 780 790 800 810 820
560 570 580 590 600 610
mKIAA1 SDLDDPKAGSVHFSEST-EHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPAR
::::::::.: :::::. :::::::::::::: : ::::: ::..:.::. :::::::::
gi|149 SDLDDPKASSSHFSESAAEHLRNGEQNPPNGEPKLEEASRQQCNQLLRRTTADGRGPPAR
830 840 850 860 870 880
620 630 640 650 660 670
mKIAA1 GGEPSRPEARLLRSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQS
:.::::::::::::::::::.::::::::::::::.::::::::::::::::::::::::
gi|149 GSEPSRPEARLLRSQSTFQLFSEAEREASWSEDRPSTPESPLLDAPFSRAYRNSIKDAQS
890 900 910 920 930 940
680 690 700 710 720 730
mKIAA1 RVLGATSFRRRDLEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPA-
::::::::::::::::::::::::::::::::::::::::..: :::::::::::::::
gi|149 RVLGATSFRRRDLEPGTPATSRPWRPRPASAHVGMRSPEASAPLSSPHTPRERHSVTPAT
950 960 970 980 990 1000
740 750 760 770 780 790
mKIAA1 ----APQAARRGPRRRLTVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSEST
:::::::: :::::.::::::::::::::::::::::: . : : :::: ::::::
gi|149 GTPPAPQAARRGARRRLTAEQKKRSYSEPEKMNEVGVSEEAESVHCVPQRPAQLRFSEST
1010 1020 1030 1040 1050 1060
800 810 820 830 840 850
mKIAA1 VADRRRIFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERA
::::::.:::::::::::::::::::::::::::::::::::::::::::::: ::::::
gi|149 VADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEPGLRERA
1070 1080 1090 1100 1110 1120
860 870 880 890 900 910
mKIAA1 QSAYLQAGPAAPDGPGLASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGR
::.:.:: ::::.:::::::::::::::::.:: ::: : :::::::.::::::::::::
gi|149 QSVYFQAVPAAPEGPGLASACSLSSLREPEVLPCKEHPHQSAADGPQTPRDRSSSFASGR
1130 1140 1150 1160 1170 1180
920 930 940 950 960 970
mKIAA1 LVGERRRWDPQVPRQLLSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERS
:::::::::::.:::::::::: :::::::: . ::::: ::.::.:::::::::::::
gi|149 LVGERRRWDPQAPRQLLSGANCGPRGVQRMDRTSRGPPSWDMVVGKSGKSKSAEDLLERS
1190 1200 1210 1220 1230 1240
980 990 1000 1010 1020 1030
mKIAA1 DTLAVPVHVRSRSSPTSDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELA
:::.:::::::::::::::::::::::: :.::::::: ::::: : :: ::.::.: :
gi|149 DTLTVPVHVRSRSSPTSDKKGQDVLLREDSGFGFVKDPY-LAGPGSRPLSYSDRGQKEQA
1250 1260 1270 1280 1290 1300
1040 1050 1060 1070 1080 1090
mKIAA1 LPLHHPTPCWNGSGCKATVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAAS
::::::. :::::: ::::.::. ::::: ::::: ::: :::::::::::::::::.:
gi|149 LPLHHPATCWNGSGYKATVVSST--ESSGAPDHLKQLRAPCPRPLSAGMHGHFPDARASS
1310 1320 1330 1340 1350
1100 1110 1120 1130 1140 1150
mKIAA1 ---LSSPLPSPVPSSYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGM
:::::::::::.::::: :::: :.:: ::::::::: :::: : ::.::
gi|149 VAPLSSPLPSPVPSGYRSQLDMDQQMGHQPLPSPASAVTQPPSPRSHE-------LEEGM
1360 1370 1380 1390 1400 1410
1160 1170 1180 1190 1200
mKIAA1 WKRTSLPQQPPPLWVKWAHAVREDGLAED-TLAPEFANLKHYRNQPSLPSSCSTSDPDTP
:::.::::.:: : :::::::::::::: . :::::.::::.:: ::::::::::::::
gi|149 WKRASLPQRPPRPW-KWAHAVREDGLAEDASSAPEFATLKHYKNQLSLPSSCSTSDPDTP
1420 1430 1440 1450 1460 1470
1210 1220 1230 1240 1250 1260
mKIAA1 GRISLRISESALQPSPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPP-SPPSEEPLV
::::::::::::: :::::::::::::.::::::: :::::::::::::: :: :.:::.
gi|149 GRISLRISESALQASPPPRGDYDDEVFVKDLHPKVPSSPTFEALPPPPPPPSPLSQEPLT
1480 1490 1500 1510 1520 1530
1270 1280 1290 1300 1310 1320
mKIAA1 NGTDDFPPPPPPQALCEVLLDGEASTEAGSGP-CRIPRVMVTREGHVPGAAHSEGSQIMT
:.:::: ::: ::.::. ::::.: : ::: : .::: .::::.::::.:.::::::.
gi|149 CGSDDFPSPPP-QAMCEAPLDGEVSEEPGSGSSCGLPRVTATREGQVPGAGHAEGSQIMV
1540 1550 1560 1570 1580
1330 1340 1350 1360 1370 1380
mKIAA1 ATPPQTSAKGSEAESNTPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHA
: ::::::.:: :::.: . .:::: :.. :::: ::::.:::::::..:::::::: ::
gi|149 AIPPQTSAEGSAAESSTAARVSAQPPLHSFPGKQPCPSQARNLTYEPADRTQDLGKKIHA
1590 1600 1610 1620 1630 1640
1390 1400 1410 1420 1430 1440
mKIAA1 EPQKTSEDIRTEALAKEIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKR
::::::::::::::::::::::::::::::::::::::::::::::: ::.:: .. :.:
gi|149 EPQKTSEDIRTEALAKEIVHQDKSLADILDPDSRMKTTMDLMEGLFPRDAGVLKEN-AER
1650 1660 1670 1680 1690 1700
1450 1460 1470 1480 1490 1500
mKIAA1 KALDITARRAGCEAKASDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQE
.:.: :.:::: :...::::::..:::::::::::::::::::::::::::::.::: ::
gi|149 RAVDSTTRRAGWEVETSDHKEAAGVLVNCPAYYSVSAAKAELLNKIKDMPEELREEEEQE
1710 1720 1730 1740 1750 1760
1510 1520 1530 1540 1550 1560
mKIAA1 DVNEKKAELIGSLTHKLESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMF
::::::::::::::::::.::::::::::::.::::::::::::::::::::::::::::
gi|149 DVNEKKAELIGSLTHKLETLQEAKGSLLTDIRLNNALGEEVEALISELCKPNEFDKYKMF
1770 1780 1790 1800 1810 1820
1570 1580 1590 1600 1610 1620
mKIAA1 IGDLDKVVNLLLSLSGRLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKEN
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
gi|149 IGDLDKVVNLLLSLSGRLARVENVLSGLGEDASKEERSSLNEKRKVLAGQHEDARELKEN
1830 1840 1850 1860 1870 1880
1630 1640 1650 1660 1670 1680
mKIAA1 LDRRERVVLDILANYLSAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 LDRRERVVLDILANYLSAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLP
1890 1900 1910 1920 1930 1940
1690 1700 1710 1720
mKIAA1 SDFRPKAGAISLPPALTGHATPGGTSVFGGVFPTLTSPL
::::::::::::::::..:.:::: .::::::::::::
gi|149 SDFRPKAGAISLPPALASHVTPGGGPAFGGVFPTLTSPL
1950 1960 1970 1980
>>gi|109499527|ref|XP_223229.4| PREDICTED: similar to sh (1986 aa)
initn: 5670 init1: 1810 opt: 7194 Z-score: 5728.0 bits: 1073.2 E(): 0
Smith-Waterman score: 9812; 85.355% identity (92.048% similar) in 1748 aa overlap (1-1726:255-1986)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|109 LGPRGGSPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
:.:.: ::::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|109 SLDMIPARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHTSADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::: :::::::: ::: :: :.:::::.::::::::.:.:::::::::
gi|109 AKWHSIPRGKGTPPLPWSQQCSGSPETA-DNPPHKAGAPMPPTRSDSYVALRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::: :::::::.:.::::::::::::::::: :::::::.::::::::
gi|109 SSLDQKRFCRPQTNSLGSQKTPFVEEQLHTVPERSPENSPPVKPKHNYTQKTQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::.:::::::::::::::::::::.:::.:::::::.:.:
gi|109 TGIYPVPSPEPHFAQVPQPSVSGNGTVYPALVKESGYTAAQGTCSKMAALDENGNQKEVS
470 480 490 500 510 520
280 290 300 310 320
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYI-YKVHFSSVPENEDSSLKRHITPPHGHSPYP
::::::::: ::.:.:::::.::: :::: :::::::::::::::::::.:::::.: ::
gi|109 RPGFAFCQPPEHDSMTPVEKKPEPRAKYIPYKVHFSSVPENEDSSLKRHVTPPHGNSLYP
530 540 550 560 570 580
330 340 350 360 370 380
mKIAA1 SERKNIHGG-SRACSNHHSLSSPQAQALHVGDD-RRPSRLSQPWEGDFQEDHNANLRQKV
:::::.::: :: ::::::: : :::: :.::: :::::: :::::::::::::::::::
gi|109 SERKNVHGGGSRPCSNHHSLPSAQAQAPHAGDDDRRPSRLFQPWEGDFQEDHNANLRQKV
590 600 610 620 630 640
390 400 410 420 430 440
mKIAA1 EREGQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRS-------KVE
::::::::: :::: :.:.:: ::::::.:::::.:.:::. ::.::::: :::
gi|109 EREGQGQGLPGNSGGTKSTFSPLQNIPENLRRQSSVDLGEGLEVYPGGRSTCATTTTKVE
650 660 670 680 690 700
450 460 470 480 490
mKIAA1 DPGRKAGASDIRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQ-TSGASQRR
::::::: : :::::::::::::::::::..: ::::::::: : : :: ::: ::::
gi|109 DPGRKAGP-DNRGYLDRSVSYPRPEGKMNAAESFHSADSRYEE-PLAAPPQQTSGMSQRR
710 720 730 740 750 760
500 510 520 530 540 550
mKIAA1 LSSSSSAAPQYRKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSS
::.::. : ::.:::::::::::.::::::::::: :::::::. .::::::::::::::
gi|109 LSASSTPALQYKKPHCSVLEKVSKIEEREQGRHRPTSVGSSAYALSYRPGRTGPTPSTSS
770 780 790 800 810 820
560 570 580 590 600 610
mKIAA1 SDLDDPKAGSVHFSEST-EHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPAR
::::::::.: :::::. :::::::::::::: : ::::: ::..:.::. :::::::::
gi|109 SDLDDPKASSSHFSESAAEHLRNGEQNPPNGEPKLEEASRQQCNQLLRRTTADGRGPPAR
830 840 850 860 870 880
620 630 640 650 660 670
mKIAA1 GGEPSRPEARLLRSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQS
:.::::::::::::::::::.::::::::::::::.::::::::::::::::::::::::
gi|109 GSEPSRPEARLLRSQSTFQLFSEAEREASWSEDRPSTPESPLLDAPFSRAYRNSIKDAQS
890 900 910 920 930 940
680 690 700 710 720 730
mKIAA1 RVLGATSFRRRDLEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPA-
::::::::::::::::::::::::::::::::::::::::..: :::::::::::::::
gi|109 RVLGATSFRRRDLEPGTPATSRPWRPRPASAHVGMRSPEASAPLSSPHTPRERHSVTPAT
950 960 970 980 990 1000
740 750 760 770 780 790
mKIAA1 ----APQAARRGPRRRLTVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSEST
:::::::: :::::.::::::::::::::::::::::: . : : :::: ::::::
gi|109 GTPPAPQAARRGARRRLTAEQKKRSYSEPEKMNEVGVSEEAESVHCVPQRPAQLRFSEST
1010 1020 1030 1040 1050 1060
800 810 820 830 840 850
mKIAA1 VADRRRIFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERA
::::::.:::::::::::::::::::::::::::::::::::::::::::::: ::::::
gi|109 VADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEPGLRERA
1070 1080 1090 1100 1110 1120
860 870 880 890 900 910
mKIAA1 QSAYLQAGPAAPDGPGLASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGR
::.:.:: ::::.:::::::::::::::::.:: ::: : :::::::.::::::::::::
gi|109 QSVYFQAVPAAPEGPGLASACSLSSLREPEVLPCKEHPHQSAADGPQTPRDRSSSFASGR
1130 1140 1150 1160 1170 1180
920 930 940 950 960 970
mKIAA1 LVGERRRWDPQVPRQLLSGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERS
:::::::::::.:::::::::: :::::::: . ::::: ::.::.:::::::::::::
gi|109 LVGERRRWDPQAPRQLLSGANCGPRGVQRMDRTSRGPPSWDMVVGKSGKSKSAEDLLERS
1190 1200 1210 1220 1230 1240
980 990 1000 1010 1020 1030
mKIAA1 DTLAVPVHVRSRSSPTSDKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELA
:::.:::::::::::::::::::::::: :.::::::: ::::: : :: ::.::.: :
gi|109 DTLTVPVHVRSRSSPTSDKKGQDVLLREDSGFGFVKDPY-LAGPGSRPLSYSDRGQKEQA
1250 1260 1270 1280 1290 1300
1040 1050 1060 1070 1080 1090
mKIAA1 LPLHHPTPCWNGSGCKATVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAAS
::::::. :::::: ::::.::. ::::: ::::: ::: :::::::::::::::::.:
gi|109 LPLHHPATCWNGSGYKATVVSST--ESSGAPDHLKQLRAPCPRPLSAGMHGHFPDARASS
1310 1320 1330 1340 1350
1100 1110 1120 1130 1140 1150
mKIAA1 ---LSSPLPSPVPSSYRSQLAMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGM
:::::::::::.::::: :::: :.:: ::::::::: :::: : ::.::
gi|109 VAPLSSPLPSPVPSGYRSQLDMDQQMGHQPLPSPASAVTQPPSPRSHE-------LEEGM
1360 1370 1380 1390 1400 1410
1160 1170 1180 1190 1200
mKIAA1 WKRTSLPQQPPPLWVKWAHAVREDGLAED-TLAPEFANLKHYRNQPSLPSSCSTSDPDTP
:::.::::.:: : :::::::::::::: . :::::.::::.:: ::::::::::::::
gi|109 WKRASLPQRPPRPW-KWAHAVREDGLAEDASSAPEFATLKHYKNQLSLPSSCSTSDPDTP
1420 1430 1440 1450 1460 1470
1210 1220 1230 1240 1250 1260
mKIAA1 GRISLRISESALQPSPPPRGDYDDEVFMKDLHPKVTSSPTFEALPPPPPP-SPPSEEPLV
::::::::::::: :::::::::::::.::::::: :::::::::::::: :: :.:::.
gi|109 GRISLRISESALQASPPPRGDYDDEVFVKDLHPKVPSSPTFEALPPPPPPPSPLSQEPLT
1480 1490 1500 1510 1520 1530
1270 1280 1290 1300 1310 1320
mKIAA1 NGTDDFPPPPPPQALCEVLLDGEASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTA
:.:::: ::: ::.::. ::::.: : ::: : .::: .::::.::::.:.::::::.:
gi|109 CGSDDFPSPPP-QAMCEAPLDGEVSEEPGSGSCGLPRVTATREGQVPGAGHAEGSQIMVA
1540 1550 1560 1570 1580
1330 1340 1350 1360 1370 1380
mKIAA1 TPPQTSAKGSEAESNTPSSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAE
::::::.:: :::.: . .:::: :.. :::: ::::.:::::::..:::::::: :::
gi|109 IPPQTSAEGSAAESSTAARVSAQPPLHSFPGKQPCPSQARNLTYEPADRTQDLGKKIHAE
1590 1600 1610 1620 1630 1640
1390 1400 1410 1420 1430 1440
mKIAA1 PQKTSEDIRTEALAKEIVHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRK
:::::::::::::::::::::::::::::::::::::::::::::: ::.:: .. :.:.
gi|109 PQKTSEDIRTEALAKEIVHQDKSLADILDPDSRMKTTMDLMEGLFPRDAGVLKEN-AERR
1650 1660 1670 1680 1690 1700
1450 1460 1470 1480 1490 1500
mKIAA1 ALDITARRAGCEAKASDHKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQED
:.: :.:::: :...::::::..:::::::::::::::::::::::::::::.::: :::
gi|109 AVDSTTRRAGWEVETSDHKEAAGVLVNCPAYYSVSAAKAELLNKIKDMPEELREEEEQED
1710 1720 1730 1740 1750 1760
1510 1520 1530 1540 1550 1560
mKIAA1 VNEKKAELIGSLTHKLESLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFI
:::::::::::::::::.::::::::::::.:::::::::::::::::::::::::::::
gi|109 VNEKKAELIGSLTHKLETLQEAKGSLLTDIRLNNALGEEVEALISELCKPNEFDKYKMFI
1770 1780 1790 1800 1810 1820
1570 1580 1590 1600 1610 1620
mKIAA1 GDLDKVVNLLLSLSGRLARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENL
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
gi|109 GDLDKVVNLLLSLSGRLARVENVLSGLGEDASKEERSSLNEKRKVLAGQHEDARELKENL
1830 1840 1850 1860 1870 1880
1630 1640 1650 1660 1670 1680
mKIAA1 DRRERVVLDILANYLSAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 DRRERVVLDILANYLSAEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPS
1890 1900 1910 1920 1930 1940
1690 1700 1710 1720
mKIAA1 DFRPKAGAISLPPALTGHATPGGTSVFGGVFPTLTSPL
:::::::::::::::..:.:::: .::::::::::::
gi|109 DFRPKAGAISLPPALASHVTPGGGPAFGGVFPTLTSPL
1950 1960 1970 1980
>>gi|219519297|gb|AAI45114.1| Unknown (protein for MGC:1 (1849 aa)
initn: 6358 init1: 6358 opt: 6374 Z-score: 5075.7 bits: 952.4 E(): 0
Smith-Waterman score: 10544; 92.410% identity (92.410% similar) in 1726 aa overlap (1-1726:255-1849)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
::::::::::::::::::::::::::::::
gi|219 LEPSGGYPPCHLLSPAKSTSSIDQLGHLHNKRDSAYSSFSTSSSIFEYPPPGGSARERSG
230 240 250 260 270 280
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
290 300 310 320 330 340
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
350 360 370 380 390 400
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
410 420 430 440 450 460
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
470 480 490 500 510 520
280 290 300 310 320 330
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 RPGFAFCQPLEHNSVTPVEKRPEPTAKYIYKVHFSSVPENEDSSLKRHITPPHGHSPYPS
530 540 550 560 570 580
340 350 360 370 380 390
mKIAA1 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 ERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKVERE
590 600 610 620 630 640
400 410 420 430 440 450
mKIAA1 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 GQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAPEVHPGGRSKVEDPGRKAGASD
650 660 670 680 690 700
460 470 480 490 500 510
mKIAA1 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 IRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRRLSSSSSAAPQY
710 720 730 740 750 760
520 530 540 550 560 570
mKIAA1 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 RKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGYRPGRTGPTPSTSSSDLDDPKAGSV
770 780 790 800 810 820
580 590 600 610 620 630
mKIAA1 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 HFSESTEHLRNGEQNPPNGEAKQEEASRPQCSHLIRRAPADGRGPPARGGEPSRPEARLL
830 840 850 860 870 880
640 650 660 670 680 690
mKIAA1 RSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRD
:::::::::::::::::::::::
gi|219 RSQSTFQLYSEAEREASWSEDRP-------------------------------------
890 900
700 710 720 730 740 750
mKIAA1 LEPGTPATSRPWRPRPASAHVGMRSPEAAVPSSSPHTPRERHSVTPAAPQAARRGPRRRL
gi|219 ------------------------------------------------------------
760 770 780 790 800 810
mKIAA1 TVEQKKRSYSEPEKMNEVGVSEEAEPTPCGPPRPAQPRFSESTVADRRRIFERDGKACST
::::::::::::::::::::::::::
gi|219 ----------------------------------AQPRFSESTVADRRRIFERDGKACST
910 920 930
820 830 840 850 860 870
mKIAA1 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 LSLSGPELKQFQQSALADYIQRKTGKRPTGAACTPEAGLRERAQSAYLQAGPAAPDGPGL
940 950 960 970 980 990
880 890 900 910 920 930
mKIAA1 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 ASACSLSSLREPEALPRKEHTHPSAADGPQAPRDRSSSFASGRLVGERRRWDPQVPRQLL
1000 1010 1020 1030 1040 1050
940 950 960 970 980 990
mKIAA1 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 SGANCEPRGVQRMDGAPGGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTS
1060 1070 1080 1090 1100 1110
1000 1010 1020 1030 1040 1050
mKIAA1 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 DKKGQDVLLREGSNFGFVKDPCCLAGPGPRSLSCSDKGQNELALPLHHPTPCWNGSGCKA
1120 1130 1140 1150 1160 1170
1060 1070 1080 1090 1100 1110
mKIAA1 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 TVASSAPPESSGASDHLKQRRAPGPRPLSAGMHGHFPDARAASLSSPLPSPVPSSYRSQL
1180 1190 1200 1210 1220 1230
1120 1130 1140 1150 1160 1170
mKIAA1 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLWVKWAHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 AMDQQTGQQPPSSPASAVTQPTSPRSPELSSPAYGLEKGMWKRTSLPQQPPPLWVKWAHA
1240 1250 1260 1270 1280 1290
1180 1190 1200 1210 1220 1230
mKIAA1 VREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 VREDGLAEDTLAPEFANLKHYRNQPSLPSSCSTSDPDTPGRISLRISESALQPSPPPRGD
1300 1310 1320 1330 1340 1350
1240 1250 1260 1270 1280 1290
mKIAA1 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 YDDEVFMKDLHPKVTSSPTFEALPPPPPPSPPSEEPLVNGTDDFPPPPPPQALCEVLLDG
1360 1370 1380 1390 1400 1410
1300 1310 1320 1330 1340 1350
mKIAA1 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 EASTEAGSGPCRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTPSSASA
1420 1430 1440 1450 1460 1470
1360 1370 1380 1390 1400 1410
mKIAA1 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 QPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEIVHQDK
1480 1490 1500 1510 1520 1530
1420 1430 1440 1450 1460 1470
mKIAA1 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 SLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASDHKEAV
1540 1550 1560 1570 1580 1590
1480 1490 1500 1510 1520 1530
mKIAA1 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 SVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLESLQEA
1600 1610 1620 1630 1640 1650
1540 1550 1560 1570 1580 1590
mKIAA1 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRLARVEN
1660 1670 1680 1690 1700 1710
1600 1610 1620 1630 1640 1650
mKIAA1 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 VLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSAEQLQD
1720 1730 1740 1750 1760 1770
1660 1670 1680 1690 1700 1710
mKIAA1 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHATPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|219 YQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTGHATPG
1780 1790 1800 1810 1820 1830
1720
mKIAA1 GTSVFGGVFPTLTSPL
::::::::::::::::
gi|219 GTSVFGGVFPTLTSPL
1840
>>gi|126330937|ref|XP_001363590.1| PREDICTED: similar to (1889 aa)
initn: 3189 init1: 1790 opt: 4389 Z-score: 3495.5 bits: 660.0 E(): 5.4e-186
Smith-Waterman score: 4821; 49.246% identity (70.184% similar) in 1791 aa overlap (1-1726:164-1889)
10 20 30
mKIAA1 KRDSAYSSFSTSSSIFEYPPPGGSARERSG
:::::::::::::::.:::: . :..: :
gi|126 LDHSGNYPPCHLLSPAKSISSIDQLTHLHNKRDSAYSSFSTSSSIIEYPPTSFSSQECSD
140 150 160 170 180 190
40 50 60 70 80 90
mKIAA1 SMDVISARGGLLEGMRQADIRYVKTVYDTRRGVSSEYEVNPSALLLQGRDAHASADSQGC
.. . :.:.::::::::::::::::::..::.:.::::: :::: . ... : .:
gi|126 TVATTPAQGSLLEGMRQADIRYVKTVYDSKRGISAEYEVNSSALLPPSGESQESMGDQDY
200 210 220 230 240 250
100 110 120 130 140 150
mKIAA1 AKWHSIPRGKGTPSPSWSQQCSGSLETATDNLPQKAGAPLPPTRSDSYAAFRHRERPSSW
:::. ::. .: ::.::::.: :: ..:::.:.:::.::.:: ::. .:: ::::::
gi|126 DKWHNHPRSGRVPLLSWNQQCSSSHETDSNNLPHKVGAPMPPARSGSYTILRHYERPSSW
260 270 280 290 300 310
160 170 180 190 200 210
mKIAA1 SSLDQKRFCRPQTNSSGSQKTPFAEDQLHTVPERSPENSPPVKSKHNYTQKAQPGQPLLP
:: ...:. :::.. :. :: : :..:::. :.::::::::: :..::: .:::::.::
gi|126 SSSEHNRYGRPQSSFPGTLKTSFPEEHLHTLLEKSPENSPPVKPKQSYTQTTQPGQPMLP
320 330 340 350 360 370
220 230 240 250 260 270
mKIAA1 TGIYPVPSPEPHFAQVPQPSVSSNGTVYPALVKESGYTAAQGTCNKMATLDENGNQNEAS
:.:::::::::::::.:: :::::: .::::.:: ::::. .: .:.::: :::::: :
gi|126 TSIYPVPSPEPHFAQMPQSSVSSNGMLYPALIKEHGYTASLNTSDKIATL-ENGNQNGPS
380 390 400 410 420 430
280 290 300 310 320
mKIAA1 RPGFAFCQPLEHNSVTPVEKRPEPTAKYI-YKVHFSSVPENEDSSLKRHITPPHGHSPY-
. . : : ..:: :. .. : .:.. :: :: : :: .. :. : ... :
gi|126 KNAVIFYQAPDYNS-PPLVEKVETLGKFFSYKPHFISDSENLRGTSLRKDEPRISEGDYM
440 450 460 470 480 490
330 340 350 360 370 380
mKIAA1 -PSERKNIHGGSRACSNHHSLSSPQAQALHVGDDRRPSRLSQPWEGDFQEDHNANLRQKV
:: .... . . ::::. :.. :.. ... :: :.: ...:::. :: :. .
gi|126 LPSGKEGLCDNVQ-FSNHHT---PRG--LKIDESKLLSRPSEPKRAEFQESPNARLQTRP
500 510 520 530 540
390 400 410 420 430
mKIAA1 EREGQGQGLSGNSGRTRSAFSSLQNIPESLRRQSNVELGEAP-EVHPGGR-------SKV
::: . ..::.: :.: ::: : : :::.. :. .: : .: .: ::.
gi|126 EREDLTEDSWNTSGKTSSSFLSLQPISPSTRRQNSQEIQVGPQEGNPDNRTACLINMSKM
550 560 570 580 590 600
440 450 460 470 480 490
mKIAA1 EDPGRKAGASDIRGYLDRSVSYPRPEGKMNAVDSVHSADSRYEESPAPALPQTSGASQRR
:. .:. . . : . :...: :::: .. .: :... :.: . :::. .::.
gi|126 EQEPKKT-VLERRDHSDQQTSRGRPEGGTKGPSSSHNSEPRHE-----VHRQTSNLTQRQ
610 620 630 640 650
500 510 520 530 540 550
mKIAA1 LSSSSSA-APQYRKPHCSVLEKVSRIEEREQGRHRPLSVGSSAYGPGY--RPGRTGPTPS
.::... .: ::: ::::::...:.:::: :: ::.: : . :: :. .
gi|126 FSSGNALHISHYGKPHFSVLEKVNKFEQREQGNWRPSSVSSYIYKTNNLERP----PSRG
660 670 680 690 700 710
560 570 580 590 600 610
mKIAA1 TSSSDLDDPKAGSVHFSESTEHLRN---GEQNPPNGEAKQEEASRPQCSHLIRRAPADGR
.: .:.. . . :.: . . . ::. ... : : .: : ..:: :.
gi|126 SSMISLENHQR-EISFQEPSPSIGSINVGENLVKDSKKKPEAVSWYLPEHQLKRAGDGGH
720 730 740 750 760 770
620 630 640 650 660 670
mKIAA1 GPPARGGEPSRPEARLLRSQSTFQLYSEAEREASWSEDRPGTPESPLLDAPFSRAYRNSI
: .. . : ::::::.: ...:.:. : :.: ..::::....:...::::::
gi|126 GLTHSESKSLKSAPLLQRSQSTFHLSNKVEEETLWRENRSSSPESPVFEVPLNQAYRNSI
780 790 800 810 820 830
680 690 700 710 720 730
mKIAA1 KDAQSRVLGATSFRRRDLEPGTPATSRPW---RPRPASAHVGMRSPEAAVPSSSPHTPRE
::::::::::::::::::. : ..:: : ::::::.:.::::.. :.::: :.:
gi|126 KDAQSRVLGATSFRRRDLDLGPSVASRARQRARQRPASAHLGLRSPETTSMSASPHIPKE
840 850 860 870 880 890
740 750 760 770 780
mKIAA1 RHSVTPAAPQAARRGP---------RRRLTVEQKKRSYSEPEKMNEVGVSEEAEPTPCGP
::..::. . :.:: :.:::..:::::::::::.:::::: .::. : :
gi|126 RHNITPTEGSPPREGPAALVARVGGRKRLTTDQKKRSYSEPEKINEVGVSGAGEPSACYP
900 910 920 930 940 950
790 800 810 820 830 840
mKIAA1 PRPAQPR-FSESTVADRRRIFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTG
: : : :.:::.:::::::.:::::::.:: ::::::::.::::::::::::::..
gi|126 QRKDVPFGFPENTVANRRRIFEREGKACSTLNLSKPELKQFQQTALADYIQRKTGKRPSS
960 970 980 990 1000 1010
850 860 870 880 890
mKIAA1 AACTPEAGLRERAQSAYLQAGPAAPDGPGLASACSLSSLREPEALPRK-------EHTHP
.. : : :.. .: .: :..::.: .::. : .
gi|126 SS-----GHR--------------PESHSLNAASSMNSLQEQSPIPRRGSATLSIELIEN
1020 1030 1040 1050
900 910 920 930 940
mKIAA1 SAADGPQA---PRDRSSSFASGRLVGERRRWDPQV-PRQLL--SGANCEPRGVQRMDGAP
..:.: ::::::: ::..: .::. : :.. : :.: . :. .: :.. ::
gi|126 LERNSPEAQVGPRDRSSSSASSHLRAERH-WHPKMEPAQVLWLGEASGQPSHPQKVTWAP
1060 1070 1080 1090 1100 1110
950 960 970 980 990 1000
mKIAA1 GGPPSWGMVAGKAGKSKSAEDLLERSDTLAVPVHVRSRSSPTSDKKGQDVLLREGSNFGF
: : : . :.:: ::::::.:::.:.:: : :::::: :::: ::.::: .:....
gi|126 EKPFSLGTTNRGASKSMSAEDLLDRSDVLTVPFHSRSRSSPISDKKCQDMLLRGNSDYSL
1120 1130 1140 1150 1160 1170
1010 1020 1030 1040 1050 1060
mKIAA1 V-KDPCCLAGPGPRSLSCSDKGQNELA-LPLHHPTPCWNGSGCKATVASSAPPESSGASD
. : : :.::: :..: : ....: . :: :.: : . . . .::.: : : :
gi|126 LGKVPSSLVGPGFRQFSHSGRSHEEKSSLP-HYPGP--HLGPHTVPNGSSVPMECSKILD
1180 1190 1200 1210 1220 1230
1070 1080 1090 1100 1110 1120
mKIAA1 HLK---QRRAPGPRPLSAGMHGHFPDARAASLSSPL-PSPVPSSYRSQLAMDQQTGQQPP
. . : :: ::.: .: : .:.... .: : : . :. :: :.::
gi|126 SQRPTSRSSAFGP-PLAAK-QGPFVSAQTSGTNSTYSPRPYLHTERDVLA-----GRQP-
1240 1250 1260 1270 1280
1130 1140 1150 1160 1170 1180
mKIAA1 SSPASAVTQPTSPRSPELSSPAYGLEKGMWK-RTSLPQQPPPLWVKWAHAVREDGLAEDT
:: :: .::. : .: :. . : . :::.::: :::....:::.: : .
gi|126 -SPK----QPQNPRNLEENSVEDLAENDIKKNKGPLPQRPPPPRVKWSQSLREDNLPEPS
1290 1300 1310 1320 1330
1190 1200 1210 1220 1230
mKIAA1 LAPEFANLKHYRNQPSLPSSCSTSDPDT-PGRI------SLRISESALQPSPPPRGDYDD
: . ::: .. :: :. .: :.. :: . :: :::::.. : :. . ::
gi|126 LPFGVPSQKHYPQHQSLSSTSTTCHPNSLPGLLTVTGKGSLPISESAFRAIPLPQEEDDD
1340 1350 1360 1370 1380 1390
1240 1250 1260 1270 1280
mKIAA1 EVFMKDLHPKVTSSPTFEALP--PPPPPSPPSEEPLV-----NGTDDFPPPPPPQALCEV
:::... .:. : .:::..:: ::::: ::: :: .. .:::::::: . :.
gi|126 EVFVQESRPRPTPNPTFKTLPLLPPPPP-PPSPPPLDLKAQDSNLEDFPPPPPPITY-EA
1400 1410 1420 1430 1440 1450
1290 1300 1310 1320 1330 1340
mKIAA1 LLDGEASTEAGSGP-CRIPRVMVTREGHVPGAAHSEGSQIMTATPPQTSAKGSEAESNTP
: : :.:. : :. .. .... .: : : ::. . : .: :
gi|126 L--GTLSSETYEEETCTSKSKMMLAASQRASTSRP-SSFIKTLGAKQTNLLSPLAAQNQP
1460 1470 1480 1490 1500 1510
1350 1360 1370 1380 1390 1400
mKIAA1 SSASAQPQLNGSPGKQLCPSQTRNLTYEPVERTQDLGKKTHAEPQKTSEDIRTEALAKEI
. .. ..:: .:. :.: .. .: . ::.:.: . . :.:: ::: ::.:::.:
gi|126 IGILGE---QSSP-EQMLPTQFPKFIQKPNNLTQELAKGSPG-PEKTLEDISTETLAKQI
1520 1530 1540 1550 1560
1410 1420 1430 1440 1450 1460
mKIAA1 VHQDKSLADILDPDSRMKTTMDLMEGLFPGDASVLMDSGAKRKALDITARRAGCEAKASD
::::::::::::::::::::::::::::: : : ... ..::.. : :.: :
gi|126 VHQDKSLADILDPDSRMKTTMDLMEGLFPQGPSFLKENNIRKKAIQRIASFPVSEGKRST
1570 1580 1590 1600 1610 1620
1470 1480 1490 1500 1510 1520
mKIAA1 HKEAVSVLVNCPAYYSVSAAKAELLNKIKDMPEELQEEEGQEDVNEKKAELIGSLTHKLE
.:: :..:.::::::.::: :::::::.:.:: : .:.: : :::::::.:: :: ::::
gi|126 EKERVGMLINCPAYYNVSAPKAELLNKLKSMPAEGDEDEDQLDVNEKKAKLIRSLRHKLE
1630 1640 1650 1660 1670 1680
1530 1540 1550 1560 1570 1580
mKIAA1 SLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYKMFIGDLDKVVNLLLSLSGRL
::.::: ::. :::::::::::::.:. .::::::.::::::.:::::::::::::::::
gi|126 SLKEAKESLFMDIKLNNALGEEVEVLVCKLCKPNELDKYKMFVGDLDKVVNLLLSLSGRL
1690 1700 1710 1720 1730 1740
1590 1600 1610 1620 1630 1640
mKIAA1 ARVENVLRGLGEDASKEERSSLNEKRKVLAGQHEDARELKENLDRRERVVLDILANYLSA
::::::: ::::::..:: ::::::.::::::::::::::::::::::::::::::::..
gi|126 ARVENVLSGLGEDADSEEWSSLNEKKKVLAGQHEDARELKENLDRRERVVLDILANYLTT
1750 1760 1770 1780 1790 1800
1650 1660 1670 1680 1690 1700
mKIAA1 EQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVRCLLESLPSDFRPKAGAISLPPALTG
:::::::::::::::::::::::::::::::::. ::::::: :: .: . . : .
gi|126 EQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQLNCLLESLPRDFLTEARTPAAPLTPET
1810 1820 1830 1840 1850 1860
1710 1720
mKIAA1 HATPGGTSVFGGVFPTLTSPL
. :: : .: . .: : : :
gi|126 EMTPDGDCTFRSGLPPLISSL
1870 1880
1726 residues in 1 query sequences
2727779818 residues in 7921681 library sequences
Tcomplib [34.26] (2 proc)
start: Sat Mar 14 12:12:58 2009 done: Sat Mar 14 12:24:35 2009
Total Scan time: 1483.110 Total Display time: 1.800
Function used was FASTA [version 34.26.5 April 26, 2007]