# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mng14235.fasta.nr -Q ../query/mKIAA0042.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 mKIAA0042, 477 aa vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library 2727779818 residues in 7921681 sequences statistics sampled from 60000 to 7920534 sequences Expectation_n fit: rho(ln(x))= 4.9550+/-0.000185; mu= 12.4095+/- 0.010 mean_var=75.9906+/-14.439, 0's: 31 Z-trim: 33 B-trim: 84 in 1/67 Lambda= 0.147128 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7921681) gi|32484161|gb|AAH54123.1| Kif14 protein [Mus musc ( 806) 3179 684.5 2.7e-194 gi|124486927|ref|NP_001074727.1| kinesin family me (1624) 3179 684.8 4.5e-194 gi|187957280|gb|AAI58133.1| Kif14 protein [Mus mus (1674) 3179 684.8 4.6e-194 gi|73960457|ref|XP_547369.2| PREDICTED: similar to (1697) 2102 456.2 3.1e-125 gi|119611721|gb|EAW91315.1| kinesin family member ( 975) 2015 437.5 7.4e-120 gi|23396633|sp|Q15058.1|KIF14_HUMAN RecName: Full= (1648) 2015 437.7 1.1e-119 gi|119611723|gb|EAW91317.1| kinesin family member (1649) 2015 437.7 1.1e-119 gi|71051763|gb|AAH98582.1| KIF14 protein [Homo sap ( 992) 2004 435.2 3.8e-119 gi|109730619|gb|AAI13743.1| Kinesin family member (1648) 2004 435.4 5.5e-119 gi|148707599|gb|EDL39546.1| mCG142634 [Mus musculu (1610) 1865 405.8 4.1e-110 gi|194227393|ref|XP_001916122.1| PREDICTED: simila (1780) 1780 387.8 1.2e-104 gi|109018931|ref|XP_001109736.1| PREDICTED: kinesi (1649) 1699 370.6 1.7e-99 gi|126306580|ref|XP_001377526.1| PREDICTED: simila (1643) 1593 348.1 9.9e-93 gi|194681399|ref|XP_609559.4| PREDICTED: similar t (1250) 1532 335.1 6.4e-89 gi|94733897|emb|CAK11016.1| novel protein similar (1307) 686 155.5 7.6e-35 gi|47216598|emb|CAG00633.1| unnamed protein produc (1522) 592 135.6 8.6e-29 gi|114574304|ref|XP_001159924.1| PREDICTED: simila ( 74) 397 93.0 2.7e-17 gi|198435310|ref|XP_002127045.1| PREDICTED: simila (1624) 267 66.7 5.3e-08 >>gi|32484161|gb|AAH54123.1| Kif14 protein [Mus musculus (806 aa) initn: 3179 init1: 3179 opt: 3179 Z-score: 3644.5 bits: 684.5 E(): 2.7e-194 Smith-Waterman score: 3179; 100.000% identity (100.000% similar) in 477 aa overlap (1-477:330-806) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSR :::::::::::::::::::::::::::::: gi|324 LGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSR 300 310 320 330 340 350 40 50 60 70 80 90 mKIAA0 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL 360 370 380 390 400 410 100 110 120 130 140 150 mKIAA0 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF 420 430 440 450 460 470 160 170 180 190 200 210 mKIAA0 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV 480 490 500 510 520 530 220 230 240 250 260 270 mKIAA0 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA 540 550 560 570 580 590 280 290 300 310 320 330 mKIAA0 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS 600 610 620 630 640 650 340 350 360 370 380 390 mKIAA0 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS 660 670 680 690 700 710 400 410 420 430 440 450 mKIAA0 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|324 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP 720 730 740 750 760 770 460 470 mKIAA0 RRACEPHGDATPAVSSGDCTPNRIQWV ::::::::::::::::::::::::::: gi|324 RRACEPHGDATPAVSSGDCTPNRIQWV 780 790 800 >>gi|124486927|ref|NP_001074727.1| kinesin family member (1624 aa) initn: 3179 init1: 3179 opt: 3179 Z-score: 3640.5 bits: 684.8 E(): 4.5e-194 Smith-Waterman score: 3179; 100.000% identity (100.000% similar) in 477 aa overlap (1-477:1148-1624) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSR :::::::::::::::::::::::::::::: gi|124 LGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSR 1120 1130 1140 1150 1160 1170 40 50 60 70 80 90 mKIAA0 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL 1180 1190 1200 1210 1220 1230 100 110 120 130 140 150 mKIAA0 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF 1240 1250 1260 1270 1280 1290 160 170 180 190 200 210 mKIAA0 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV 1300 1310 1320 1330 1340 1350 220 230 240 250 260 270 mKIAA0 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA 1360 1370 1380 1390 1400 1410 280 290 300 310 320 330 mKIAA0 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS 1420 1430 1440 1450 1460 1470 340 350 360 370 380 390 mKIAA0 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS 1480 1490 1500 1510 1520 1530 400 410 420 430 440 450 mKIAA0 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|124 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP 1540 1550 1560 1570 1580 1590 460 470 mKIAA0 RRACEPHGDATPAVSSGDCTPNRIQWV ::::::::::::::::::::::::::: gi|124 RRACEPHGDATPAVSSGDCTPNRIQWV 1600 1610 1620 >>gi|187957280|gb|AAI58133.1| Kif14 protein [Mus musculu (1674 aa) initn: 3179 init1: 3179 opt: 3179 Z-score: 3640.4 bits: 684.8 E(): 4.6e-194 Smith-Waterman score: 3179; 100.000% identity (100.000% similar) in 477 aa overlap (1-477:1198-1674) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSR :::::::::::::::::::::::::::::: gi|187 LGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSR 1170 1180 1190 1200 1210 1220 40 50 60 70 80 90 mKIAA0 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL 1230 1240 1250 1260 1270 1280 100 110 120 130 140 150 mKIAA0 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF 1290 1300 1310 1320 1330 1340 160 170 180 190 200 210 mKIAA0 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV 1350 1360 1370 1380 1390 1400 220 230 240 250 260 270 mKIAA0 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA 1410 1420 1430 1440 1450 1460 280 290 300 310 320 330 mKIAA0 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 QDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGSRQQVSKLLS 1470 1480 1490 1500 1510 1520 340 350 360 370 380 390 mKIAA0 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 LASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHSASAGS 1530 1540 1550 1560 1570 1580 400 410 420 430 440 450 mKIAA0 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|187 CGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEEQCKSDRADCGKSGP 1590 1600 1610 1620 1630 1640 460 470 mKIAA0 RRACEPHGDATPAVSSGDCTPNRIQWV ::::::::::::::::::::::::::: gi|187 RRACEPHGDATPAVSSGDCTPNRIQWV 1650 1660 1670 >>gi|73960457|ref|XP_547369.2| PREDICTED: similar to Kin (1697 aa) initn: 1286 init1: 565 opt: 2102 Z-score: 2404.8 bits: 456.2 E(): 3.1e-125 Smith-Waterman score: 2102; 67.284% identity (87.037% similar) in 486 aa overlap (2-477:1213-1697) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::::::: ::::::::..::::.::::::: gi|739 GISTFWSLEKFESKLAAMKELYESNNSNKSEDVFCDPEDEWEPDITNVPVSSFSRRRSRS 1190 1200 1210 1220 1230 1240 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::.:: :::::..:::::::::: :::::.:.:::::::::::::::.:: gi|739 LMKNRRISGCLYDIQAHPIQSLHSSHSSGLMEKSSTIYSSSAESFLPGICKELIGSSLDF 1250 1260 1270 1280 1290 1300 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC ::::.:::::.:::::::.:....:..::::::::::::: ::::: :::::::::::.: gi|739 LGQSYDEEKTMADSLINNFLKIYHGLFAISKAHEEQDEESPDNLFSSDRAAQALTIQVTC 1310 1320 1330 1340 1350 1360 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.:::: : ::::..::::.::::..::::::::::::::::::::::::::. gi|739 AFEQLVVLIKHWLDDTLPCTSTARLEEELRQEVKKLGGYLQLFLQGCCSDISSMVKEAQK 1370 1380 1390 1400 1410 1420 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLENSS-KVSSTQE-FMAALQDGVTSGMKSLLDSG :... :::::. :::::::::::: :.::: ::.:.:: :: :: :::. ::: ::::: gi|739 KIIQTIQQAVKYVGQLAVLKGSKLHFLRNSSNKVASVQEDFMDALCDGVSLGMKILLDSG 1430 1440 1450 1460 1470 1480 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS-RQQV :: :..:...: :: ...::::::::...: .: ::: :::.::::::: :..: :.: gi|739 LEKAKELQHELLRQCTQNEVTKQMKAKATELIGCLENMFAEWKTKSFRTQLQQNSGYQDV 1490 1500 1510 1520 1530 1540 330 340 350 360 370 380 mKIAA0 SKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAHS .:....: :::::: ::.::...:.:::::: :: . :..:.:..::::. .:.:.: : gi|739 KKMVNFAPEFLKLKHCLEQTIQIIISALRGCHSDKNLLQNCVESLCSLAKDFHDDLSMCS 1550 1560 1570 1580 1590 1600 390 400 410 420 430 440 mKIAA0 ASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDRA .: .: ...:.. :::..::::::.: : : : : ::.:..:..:: : ::.:. gi|739 TSLDNCEKRIPQVGHGGLESVVKSLLLCLESEERPDLLKSWETCNQNTREEGQQSKSSRT 1610 1620 1630 1640 1650 1660 450 460 470 mKIAA0 DC--GKSGPRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: ..:: .: . :: ::::: gi|739 DSVRNKGVPKRVYELHG-SSPAGTSEESTPRRIQWV 1670 1680 1690 >>gi|119611721|gb|EAW91315.1| kinesin family member 14, (975 aa) initn: 1307 init1: 544 opt: 2015 Z-score: 2308.2 bits: 437.5 E(): 7.4e-120 Smith-Waterman score: 2015; 64.887% identity (86.242% similar) in 487 aa overlap (2-477:490-975) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::.:::: ::::::::..:::::::::::: gi|119 GISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRS 460 470 480 490 500 510 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::::: :::....::::::::.: :::::::.:::::::::::::::.:: gi|119 LMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDF 520 530 540 550 560 570 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC .:::.:::.::::::::..:...::..::::::::::::::::::: ::: :.::::.:: gi|119 FGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTAC 580 590 600 610 620 630 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.::::.:.::::. :::::::::..::::::::::::::: :::::.::::. gi|119 AFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQK 640 650 660 670 680 690 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLEN-SSKVSSTQE-FMAALQDGVTSGMKSLLDSG ....:.::::. :::::::::::: ::: ..:..:.:: :: :. ::: ::: ::::: gi|119 NAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSG 700 710 720 730 740 750 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS--RQQ :: :..:...: :: ...::::.::.... . :::: :: . :::: :.:: . :. gi|119 LEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQD 760 770 780 790 800 810 330 340 350 360 370 380 mKIAA0 VSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAH ..... : :::::: ::....:.:.:::.:: ::.. :..:.:.: .:: ..::::. gi|119 FKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVP 820 830 840 850 860 870 390 400 410 420 430 440 mKIAA0 SASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDR :.:.:: ... . .::::::::::.::: ::: : ::::. ..:.::: : ::. gi|119 STSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSG 880 890 900 910 920 930 450 460 470 mKIAA0 ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: ..::::: .:::.::::: gi|119 IDGSKNKGVPKRVYELHG-SSPAVSSEECTPSRIQWV 940 950 960 970 >>gi|23396633|sp|Q15058.1|KIF14_HUMAN RecName: Full=Kine (1648 aa) initn: 1307 init1: 544 opt: 2015 Z-score: 2305.2 bits: 437.7 E(): 1.1e-119 Smith-Waterman score: 2015; 64.887% identity (86.242% similar) in 487 aa overlap (2-477:1163-1648) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::.:::: ::::::::..:::::::::::: gi|233 GISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRS 1140 1150 1160 1170 1180 1190 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::::: :::....::::::::.: :::::::.:::::::::::::::.:: gi|233 LMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDF 1200 1210 1220 1230 1240 1250 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC .:::.:::.::::::::..:...::..::::::::::::::::::: ::: :.::::.:: gi|233 FGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTAC 1260 1270 1280 1290 1300 1310 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.::::.:.::::. :::::::::..::::::::::::::: :::::.::::. gi|233 AFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQK 1320 1330 1340 1350 1360 1370 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLEN-SSKVSSTQE-FMAALQDGVTSGMKSLLDSG ....:.::::. :::::::::::: ::: ..:..:.:: :: :. ::: ::: ::::: gi|233 NAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSG 1380 1390 1400 1410 1420 1430 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS--RQQ :: :..:...: :: ...::::.::.... . :::: :: . :::: :.:: . :. gi|233 LEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQD 1440 1450 1460 1470 1480 1490 330 340 350 360 370 380 mKIAA0 VSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAH ..... : :::::: ::....:.:.:::.:: ::.. :..:.:.: .:: ..::::. gi|233 FKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVP 1500 1510 1520 1530 1540 1550 390 400 410 420 430 440 mKIAA0 SASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDR :.:.:: ... . .::::::::::.::: ::: : ::::. ..:.::: : ::. gi|233 STSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSG 1560 1570 1580 1590 1600 1610 450 460 470 mKIAA0 ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: ..::::: .:::.::::: gi|233 IDGSKNKGVPKRVYELHG-SSPAVSSEECTPSRIQWV 1620 1630 1640 >>gi|119611723|gb|EAW91317.1| kinesin family member 14, (1649 aa) initn: 1307 init1: 544 opt: 2015 Z-score: 2305.2 bits: 437.7 E(): 1.1e-119 Smith-Waterman score: 2015; 64.887% identity (86.242% similar) in 487 aa overlap (2-477:1164-1649) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::.:::: ::::::::..:::::::::::: gi|119 GISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRS 1140 1150 1160 1170 1180 1190 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::::: :::....::::::::.: :::::::.:::::::::::::::.:: gi|119 LMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDF 1200 1210 1220 1230 1240 1250 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC .:::.:::.::::::::..:...::..::::::::::::::::::: ::: :.::::.:: gi|119 FGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTAC 1260 1270 1280 1290 1300 1310 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.::::.:.::::. :::::::::..::::::::::::::: :::::.::::. gi|119 AFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQK 1320 1330 1340 1350 1360 1370 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLEN-SSKVSSTQE-FMAALQDGVTSGMKSLLDSG ....:.::::. :::::::::::: ::: ..:..:.:: :: :. ::: ::: ::::: gi|119 NAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSG 1380 1390 1400 1410 1420 1430 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS--RQQ :: :..:...: :: ...::::.::.... . :::: :: . :::: :.:: . :. gi|119 LEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQD 1440 1450 1460 1470 1480 1490 330 340 350 360 370 380 mKIAA0 VSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAH ..... : :::::: ::....:.:.:::.:: ::.. :..:.:.: .:: ..::::. gi|119 FKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVP 1500 1510 1520 1530 1540 1550 390 400 410 420 430 440 mKIAA0 SASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDR :.:.:: ... . .::::::::::.::: ::: : ::::. ..:.::: : ::. gi|119 STSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSG 1560 1570 1580 1590 1600 1610 450 460 470 mKIAA0 ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: ..::::: .:::.::::: gi|119 IDGSKNKGVPKRVYELHG-SSPAVSSEECTPSRIQWV 1620 1630 1640 >>gi|71051763|gb|AAH98582.1| KIF14 protein [Homo sapiens (992 aa) initn: 1296 init1: 544 opt: 2004 Z-score: 2295.4 bits: 435.2 E(): 3.8e-119 Smith-Waterman score: 2004; 64.682% identity (86.037% similar) in 487 aa overlap (2-477:507-992) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::.:::: ::::::::..:::::::::::: gi|710 GISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRS 480 490 500 510 520 530 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::::: :::....::::::::.: :::::::.:::::::::::::::.:: gi|710 LMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDF 540 550 560 570 580 590 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC .:::.:::.::::::::..:...::..::::::::::::::::::: ::: :.::::.:: gi|710 FGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTAC 600 610 620 630 640 650 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.::::.:.::::. :::::::::..::::::::::::::: :::::.::::. gi|710 AFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQK 660 670 680 690 700 710 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLEN-SSKVSSTQE-FMAALQDGVTSGMKSLLDSG ....:.::::. :::::::::::: ::: ..:..:.:: :: :. ::: ::: ::::: gi|710 NAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSG 720 730 740 750 760 770 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS--RQQ :: :..:...: :: ...::::.::.... . :::: :: . :::: :.:: . :. gi|710 LEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQD 780 790 800 810 820 830 330 340 350 360 370 380 mKIAA0 VSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAH ..... : :::::: ::....:.:.:::.:: ::.. :..:.:.: .:: ..::::. gi|710 FKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVP 840 850 860 870 880 890 390 400 410 420 430 440 mKIAA0 SASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDR :.:.:: ... . .::::::::::.::: ::: : ::::. ..:.::: : ::. gi|710 STSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSG 900 910 920 930 940 950 450 460 470 mKIAA0 ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: .. :::: .:::.::::: gi|710 IDGSKNKGVPKRVYELHG-SSAAVSSEECTPSRIQWV 960 970 980 990 >>gi|109730619|gb|AAI13743.1| Kinesin family member 14 [ (1648 aa) initn: 1296 init1: 544 opt: 2004 Z-score: 2292.5 bits: 435.4 E(): 5.5e-119 Smith-Waterman score: 2004; 64.682% identity (86.037% similar) in 487 aa overlap (2-477:1163-1648) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSRS ::.:::: ::::::::..:::::::::::: gi|109 GISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEWEPDITDAPVSSLSRRRSRS 1140 1150 1160 1170 1180 1190 40 50 60 70 80 mKIAA0 LMKNRRVSGCLHDI--HPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDF ::::::.::::::: :::....::::::::.: :::::::.:::::::::::::::.:: gi|109 LMKNRRISGCLHDIQVHPIKNLHSSHSSGLMDKSSTIYSNSAESFLPGICKELIGSSLDF 1200 1210 1220 1230 1240 1250 90 100 110 120 130 140 mKIAA0 LGQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFS-DRAAQALTIQVAC .:::.:::.::::::::..:...::..::::::::::::::::::: ::: :.::::.:: gi|109 FGQSYDEERTIADSLINSFLKIYNGLFAISKAHEEQDEESQDNLFSSDRAIQSLTIQTAC 1260 1270 1280 1290 1300 1310 150 160 170 180 190 200 mKIAA0 AFEQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQN ::::::::.::::.:.::::. :::::::::..::::::::::::::: :::::.::::. gi|109 AFEQLVVLMKHWLSDLLPCTNIARLEDELRQEVKKLGGYLQLFLQGCCLDISSMIKEAQK 1320 1330 1340 1350 1360 1370 210 220 230 240 250 260 mKIAA0 KVMKIIQQAVQCVGQLAVLKGSKLCVLEN-SSKVSSTQE-FMAALQDGVTSGMKSLLDSG ....:.::::. :::::::::::: ::: ..:..:.:: :: :. ::: ::: ::::: gi|109 NAIQIVQQAVKYVGQLAVLKGSKLHFLENGNNKAASVQEEFMDAVCDGVGLGMKILLDSG 1380 1390 1400 1410 1420 1430 270 280 290 300 310 320 mKIAA0 LETAQDLRQDLSRQSAREEVTKQMKASTVEWVGSLENAVAEWRTKSFRTQAQEGS--RQQ :: :..:...: :: ...::::.::.... . :::: :: . :::: :.:: . :. gi|109 LEKAKELQHELFRQCTKNEVTKEMKTNAMGLIRSLENIFAESKIKSFRRQVQEENFEYQD 1440 1450 1460 1470 1480 1490 330 340 350 360 370 380 mKIAA0 VSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTETICSLARKLHSDFSAH ..... : :::::: ::....:.:.:::.:: ::.. :..:.:.: .:: ..::::. gi|109 FKRMVNRAPEFLKLKHCLEKAIEIIISALKGCHSDINLLQTCVESIRNLASDFYSDFSVP 1500 1510 1520 1530 1540 1550 390 400 410 420 430 440 mKIAA0 SASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESCSSNSKEE--QCKSDR :.:.:: ... . .::::::::::.::: ::: : ::::. ..:.::: : ::. gi|109 STSVGSYESRVTHIVHQELESLAKSLLFCFESEESPDLLKPWETYNQNTKEEHQQSKSSG 1560 1570 1580 1590 1600 1610 450 460 470 mKIAA0 ADCGKSG--PRRACEPHGDATPAVSSGDCTPNRIQWV : .:. :.:. : :: .. :::: .:::.::::: gi|109 IDGSKNKGVPKRVYELHG-SSAAVSSEECTPSRIQWV 1620 1630 1640 >>gi|148707599|gb|EDL39546.1| mCG142634 [Mus musculus] (1610 aa) initn: 3166 init1: 1861 opt: 1865 Z-score: 2133.2 bits: 405.8 E(): 4.1e-110 Smith-Waterman score: 3007; 85.484% identity (85.484% similar) in 558 aa overlap (1-477:1053-1610) 10 20 30 mKIAA0 DEDVFCDPADEWEPDITSTPVSSLSRRRSR :::::::::::::::::::::::::::::: gi|148 LGISTFWSLEKFESKLAAMKELYESNGGDRDEDVFCDPADEWEPDITSTPVSSLSRRRSR 1030 1040 1050 1060 1070 1080 40 50 60 70 80 90 mKIAA0 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 SLMKNRRVSGCLHDIHPIQSMQSSHSSGLMEKPSTIYSNSSESFLPGICKELIGSSIDFL 1090 1100 1110 1120 1130 1140 100 110 120 130 140 150 mKIAA0 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 GQSFDEEKTIADSLINNLLRLHNGVIAISKAHEEQDEESQDNLFSDRAAQALTIQVACAF 1150 1160 1170 1180 1190 1200 160 170 180 190 200 210 mKIAA0 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 EQLVVLFKHWLGDFLPCTGSARLEDELRQDIKKLGGYLQLFLQGCCSDISSMVKEAQNKV 1210 1220 1230 1240 1250 1260 220 230 240 250 260 270 mKIAA0 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 MKIIQQAVQCVGQLAVLKGSKLCVLENSSKVSSTQEFMAALQDGVTSGMKSLLDSGLETA 1270 1280 1290 1300 1310 1320 280 mKIAA0 QDLRQDLSRQSAREE--------------------------------------------- ::::::::::::::: gi|148 QDLRQDLSRQSAREELLSDYEPPLLGYTQGTGNSQVPQSKYAELLAIIEELGKEVRLTYA 1330 1340 1350 1360 1370 1380 290 300 mKIAA0 ------------------------------------VTKQMKASTVEWVGSLENAVAEWR :::::::::::::::::::::::: gi|148 GSKSAMERLKRGIIHAQSLVRECLAETERNARSYSLVTKQMKASTVEWVGSLENAVAEWR 1390 1400 1410 1420 1430 1440 310 320 330 340 350 360 mKIAA0 TKSFRTQAQEGSRQQVSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 TKSFRTQAQEGSRQQVSKLLSLASEFLKLKSCLQQTVEMIVSALRGCPSDLHCLRSCTET 1450 1460 1470 1480 1490 1500 370 380 390 400 410 420 mKIAA0 ICSLARKLHSDFSAHSASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|148 ICSLARKLHSDFSAHSASAGSCGNELPRADCEELESLAKSLLLCFECGESPGLSKPWESC 1510 1520 1530 1540 1550 1560 430 440 450 460 470 mKIAA0 SSNSKEEQCKSDRADCGKSGPRRACEPHGDATPAVSSGDCTPNRIQWV :::::::::::::::::::::::::::::::::::::::::::::::: gi|148 SSNSKEEQCKSDRADCGKSGPRRACEPHGDATPAVSSGDCTPNRIQWV 1570 1580 1590 1600 1610 477 residues in 1 query sequences 2727779818 residues in 7921681 library sequences Tcomplib [34.26] (2 proc) start: Thu Mar 12 14:54:33 2009 done: Thu Mar 12 15:01:24 2009 Total Scan time: 924.350 Total Display time: 0.220 Function used was FASTA [version 34.26.5 April 26, 2007]