FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA4130.ptfa, 194 aa
 vs ./tmplib.26680 library

1768823 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 3.7038+/-0.00408; mu= 16.9595+/- 0.276
 mean_var=73.6052+/-16.740, 0's: 0 Z-trim: 6  B-trim: 16 in 1/35
 Lambda= 0.1495

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 36, opt: 24, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0717  ( 616 res)   mbg08106                   ( 616)  385   92 5.4e-20
mKIAA3012  ( 253 res)   mph02039                   ( 253)  287   70 7.7e-14
mKIAA0118  ( 253 res)   mni13228                   ( 253)  269   66 1.1e-12


>>mKIAA0717  ( 616 res)   mbg08106                        (616 aa)
 initn: 350 init1: 227 opt: 385  Z-score: 451.3  bits: 91.9 E(): 5.4e-20
Smith-Waterman score: 410;  39.500% identity (45.402% ungapped) in 200 aa overlap (8-184:40-236)

                                      10        20              30 
mKIAA4                        VMAAIRKKLVIVGDGACGKTCLL------IVFSKDQF
                                     : :.:::.: ::: :.       .... :.
mKIAA0 PTLEITPSHVVVSQLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQL
      10        20        30        40        50        60         

              40                  50        60        70        80 
mKIAA4 PEVYVPTVF--ENYVADIEV--------DGKQVELALWDTAGQEDYDRLRPLSYPDTDVI
         ..::::.  ..: .  ::        :  .: : :::: :  :. . : ..:  .::.
mKIAA0 LATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVV
      70        80        90       100       110         120       

              90       100       110       120            130      
mKIAA4 LMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDE-----HTRRELAK-M
       ..:::: .:.::...   : ::.::::: .:.:::: . :::  .     ..:: ::. .
mKIAA0 VLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPI
       130       140       150       160       170       180       

          140       150       160       170       180       190    
mKIAA4 K-QEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL
       : .: . ::.::..:...: . :.: :. .. :...::. : :::: .::          
mKIAA0 KPNEILPPEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLR
       190       200        210       220       230       240      

mKIAA0 NVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHK
        250       260       270       280       290       300      

>>mKIAA3012  ( 253 res)   mph02039                        (253 aa)
 initn: 255 init1: 156 opt: 287  Z-score: 340.9  bits: 70.2 E(): 7.7e-14
Smith-Waterman score: 294;  31.111% identity (34.356% ungapped) in 180 aa overlap (8-185:61-225)

                                      10        20        30       
mKIAA4                        VMAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVP
                                     ::...::.. ::.:::. :. : . : :. 
mKIAA3 GCVSKGGGGGGGGGSCSDMSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYIS
               40        50        60        70        80        90

        40         50        60        70        80        90      
mKIAA4 TVFENY-VADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI
       :.  .. .  ::.::: ..:  ::::::: .  .    :  .  :.. ... . .:..:.
mKIAA3 TIGVDFKIRTIELDGKTIKLQRWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNV
              100       110       120       130       140       150

        100        110       120       130       140       150     
mKIAA4 PEKWTPEVKHFCP-NVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAF
        ..:  :. ..   ::  .::::: :: . . .    ::            ..:. .: .
mKIAA3 -KQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAK------------EFADSLG-I
               160       170       180                   190       

         160       170       180       190                       
mKIAA4 GYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLIL                   
        ..: :::.  .:.. : :.  : .. : :                            
mKIAA3 PFLETSAKNATNVEQSF-MTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC
        200       210        220       230       240       250   

>>mKIAA0118  ( 253 res)   mni13228                        (253 aa)
 initn: 175 init1: 175 opt: 269  Z-score: 319.9  bits: 66.4 E(): 1.1e-12
Smith-Waterman score: 296;  28.495% identity (31.361% ungapped) in 186 aa overlap (8-190:50-221)

                                      10        20        30       
mKIAA4                        VMAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVP
                                     :.:..:.:  ::: :.. . ...: . .. 
mKIAA0 GAGLGRRGSGGGMAAAGGGAAAAAGRAYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHIT
      20        30        40        50        60        70         

        40         50        60        70        80        90      
mKIAA4 TVFENYVAD-IEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENI
       :.  ....  ... ::.:.::.::::::: .  : :. : :..  .. ... . ::....
mKIAA0 TLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDVTDEDSFQKV
      80        90       100       110       120       130         

        100       110        120       130       140       150     
mKIAA4 PEKWTPEVKHFCPN-VPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAF
        ..:. :....  : . . .:::: ::....:            :. .:....:. .:: 
mKIAA0 -KNWVKELRKMLGNEICLCIVGNKIDLEKERH------------VSIQEAESYAESVGAK
      140       150       160       170                   180      

         160       170        180       190                        
mKIAA4 GYMECSAKTKDGVREVF-EMATRAALQARRGKKKSGCLIL                    
        : . ::: . :..:.: ..  :    :.  .. .:                        
mKIAA0 HY-HTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQAGAARRGVQIIDDEPQAQS
         190       200       210       220       230       240     

mKIAA0 SGGCCSSG
         250   




194 residues in 1 query   sequences
1768823 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 11:02:48 2006 done: Mon Mar 27 11:02:49 2006
 Scan time:  0.380 Display time:  0.020

Function used was FASTA [version 3.4t11 Apr 17, 2002]