FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA4022.ptfa, 798 aa
 vs ./tmplib.26680 library

1768219 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 4.0792+/-0.00426; mu= 20.4086+/- 0.287
 mean_var=84.5044+/-18.567, 0's: 0 Z-trim: 4  B-trim: 0 in 0/36
 Lambda= 0.1395

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0177  ( 1269 res)   mid01021                  (1269)  439   99 3.1e-21


>>mKIAA0177  ( 1269 res)   mid01021                       (1269 aa)
 initn: 425 init1: 302 opt: 439  Z-score: 473.6  bits: 99.2 E(): 3.1e-21
Smith-Waterman score: 664;  26.230% identity (29.250% ungapped) in 610 aa overlap (11-598:620-1188)

                                   10        20        30        40
mKIAA4                     KRAITMEHHCGLITSNKETVPLKNISVTLSINEFVAAVVA
                                     ::  .. . ::: .. .   . .::: :..
mKIAA0 VEEQRAEPSSVPEAGDFQLPDIKPFTNIKAGLQDASTNPVPLDSVHIKGRVIDFVAQVIV
     590       600       610       620       630       640         

               50        60        70        80        90       100
mKIAA4 TLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGH
         .: :. .::.:: ..::.:. .:: .:::...::.::.:...: .:..::.::.::::
mKIAA0 FQTYTNQSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEARQEYREAVSQGH
     650       660       670       680       690       700         

              110       120       130       140       150       160
mKIAA4 QAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQELPLETDGALRYLLPAILNPRYQL
        :::...:  . :::. .:::: : ::: . . :. :: ...  :. ...:. . :  : 
mKIAA0 GAYLMDQD--TPDVFTVSVGNLPPRAKVLIKITYITELSIQSPVAI-FFIPGTVAPWQQ-
     710         720       730       740       750        760      

              170       180         190       200       210        
mKIAA4 SEQSANSCLNIQKPTVPLEDL--PYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTS
        ... :  :.    :. ....    ..... .:   . :: ..:. .    :  :: :  
mKIAA0 -DKALNENLQDTVETIRIKEIGAEQSFSLAMSIEMPYMIEFISSD-THELRQKSTDCK--
          770       780       790       800        810       820   

      220       230        240       250       260       270       
mKIAA4 AQVSLTEGHKFDRD-VELLIYYNEVHSPSVAVEMGMLDMKPDSLMGAPSAMVSFYPDIPE
       : :: .:: ..:     : :   ... : . ::      .:..   . . :. : :.. .
mKIAA0 AVVSTVEGSSLDSGGFSLHIGLRDAYLPRMWVEK-----HPEKE--SEACMLVFQPELAD
             830       840       850            860         870    

       280        290       300       310       320       330      
mKIAA4 VEAS-KACGEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGF
       :  . .. .: .. .: :.::..   :.         ::.. :  :. :      ::. :
mKIAA0 VLPDLRGKNEVIICLDCSSSMEGVTFTQ---------AKQVALYALSLLGEEQKVNIMQF
          880       890       900                910       920     

        340       350       360       370       380       390      
mKIAA4 GSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQ-LF
       :..:...:      :.. :  :.. . .   ..:.:..   :   : .   :.. .. ..
mKIAA0 GTGYKELFSYPKCITDSKM--ATEFIMSAAPSMGNTDFWKVLR--YLSLLYPSEGFRNIL
         930       940         950       960         970       980 

         400       410       420       430       440       450     
mKIAA4 VFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRM
       ...::....   ... :: : .. : :. ..:. :.  ....... ..:.  ....:.. 
mKIAA0 LISDGHLQSESLTLQLVKRNIQHTRVFTCAVGSTANRHILRTLSQCGAGVFEYFNSKSKH
             990      1000      1010      1020      1030      1040 

             460       470            480       490       500      
mKIAA4 ----QTKALGSLKFALQCAVDNISLSW-----DLPPGLSVKMLSPEQLTIFRGQRLIIYA
           : .:  .   . .:   ..:..:     : :  :..    :   ..:...::..: 
mKIAA0 SWKKQIEAQMTRIRSPSC--HSVSVKWQQLSRDAPEPLQAPAWVP---SLFHNDRLLVY-
            1050        1060      1070      1080         1090      

        510       520       530       540       550       560      
mKIAA4 QLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKANDNFTIHRLAAKSLIQTKDFG-
          :..:.  ..    :. ..: . . . :. .   :.. .. ::.:::..::.  . : 
mKIAA0 ---GFIPHCTQA---TLQAFIQEKEFCTMVSTTELQKTTGTM-IHKLAARALIRDYEDGI
           1100         1110      1120      1130       1140        

           570            580       590       600       610        
mKIAA4 --SQEASKEEKEDVMN-----ISLQSGVLSSFTAFIAINKELNKPVQGPLAHRVIPRPVM
         ..:...: :...:.     .: .......::.:.:..:.                   
mKIAA0 LHDDETNHEMKKNIMKSLIIELSKENSLITQFTSFVAVEKRDVNEIPFANVPNISELVAK
     1150      1160      1170      1180      1190      1200        

      620       630       640       650       660       670        
mKIAA4 AGSSSMRFYSSFSGGFKGPQPRSLRVPAYDLCSAESANLVLKKSACSAIQKKKTNSSTNK
                                                                   
mKIAA0 EDVDFLPYVSWQEKQPEASISQTEIDSSRLKHNKLSDGHGVLQPVSVSSEVNEKPSLLLA
     1210      1220      1230      1240      1250      1260        




798 residues in 1 query   sequences
1768219 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 10:59:28 2006 done: Mon Mar 27 10:59:29 2006
 Scan time:  0.900 Display time:  0.060

Function used was FASTA [version 3.4t11 Apr 17, 2002]