FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0772.ptfa, 324 aa
vs ./tmplib.26680 library
1768693 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 5.4166+/-0.00449; mu= 9.7884+/- 0.300
mean_var=103.4948+/-23.977, 0's: 0 Z-trim: 6 B-trim: 0 in 0/36
Lambda= 0.1261
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA4220 ( 516 res) mia04077 ( 516) 394 82 8e-17
mKIAA0704 ( 824 res) mbg11653 ( 824) 271 60 6e-10
mKIAA4128 ( 1002 res) mbf00283 (1002) 267 59 1.1e-09
mKIAA1451 ( 429 res) mth01486 ( 429) 258 57 2e-09
mKIAA1534 ( 493 res) mph00515 ( 493) 210 48 9.2e-07
>>mKIAA4220 ( 516 res) mia04077 (516 aa)
initn: 577 init1: 244 opt: 394 Z-score: 394.4 bits: 81.9 E(): 8e-17
Smith-Waterman score: 632; 36.765% identity (43.403% ungapped) in 340 aa overlap (1-324:213-516)
10 20
mKIAA0 ELIR-EDLGFRFISEQVSHHPPISAFYSEG
:: : :. :.: : :::::::: .: ..:.
mKIAA4 CYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSICEQVSHHPPAAAHHAES
190 200 210 220 230 240
30 40 50 60 70 80
mKIAA0 LNQDFRFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWI
: . .. : :: :: . : ::: . . .. ::: . : :::.:.:.:::
mKIAA4 KN-GWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHSTGHHYTWKKVTTTVHNIIVGKLWI
250 260 270 280 290 300
90 100 110 120 130 140
mKIAA0 EQYGIVEIVNHRTGDKCILHFKPCGLFGKELHR-VEGYIQDKNRKKLFIMYGKWTECLWG
.: : ..::::.::::: :.: : . :.... : : : . : . : : . : : : .
mKIAA4 DQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGTWDEKM--
310 320 330 340 350
150 160 170 180 190 200
mKIAA0 IDPASYESFKKQEKRGDQARKAKMDDGPEKANSDVPGDVADDVPVAQETVQVIPGSKLLW
. :: : :... :.. : : .: : .::
mKIAA4 ------DCFKVQAASGENGGDARQR-GHEAEDSRV----------------------MLW
360 370 380 390
210 220 230 240 250 260
mKIAA0 RINSRPPNSAQMYNFTSFTVSLNELESGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKE
. : : :. .:: :. ....:: :.: ::: ::::: : :::: : :. ::.
mKIAA4 KRNPLPKNAENMYYFSELALTLNAWEGGTA----PTDSRLRPDQRLMENGRWDEANAEKQ
400 410 420 430 440
270 280 290 300 310
mKIAA0 RLEEKQREARKERAKEDAE----------WRTRWFSPGNNPYTGAPDWLYAGHYFE----
::::::: .::.: : :. ... :: ..: : .:.:.:.:
mKIAA4 RLEEKQRLSRKKREAEAAKATEDGTPHDPYKALWFERKKDPVTRELTHIYSGEYWECKEK
450 460 470 480 490 500
320
mKIAA0 RNFSDCPDIY
.....::::.
mKIAA4 QDWGSCPDIF
510
>>mKIAA0704 ( 824 res) mbg11653 (824 aa)
initn: 451 init1: 190 opt: 271 Z-score: 271.0 bits: 59.8 E(): 6e-10
Smith-Waterman score: 317; 28.270% identity (36.612% ungapped) in 237 aa overlap (21-253:638-824)
10 20 30 40
mKIAA0 ELIREDLGFRFISEQVSHHPPISAFYSEGLNQD--FRFHG-SIYPKLKFW
:. . : . :: :.: . .. : :::
mKIAA0 SPLERMVYVAAFAISAYASSYFRAGSKPFNPVLGETYECIRQDKGFQFFAEQMRWKNKFW
610 620 630 640 650 660
50 60 70 80 90 100
mKIAA0 GKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNHRTGD-KC
:::.: : :: . : .. . :.. : :.::.. :: :::.:: ..: : . .:
mKIAA0 GKSMEIVPIGTTHVTLPAFGDHFEWNKVTSCIHNILSGQRWIEHYGEIDIKNLNDDSCHC
670 680 690 700 710 720
110 120 130 140 150 160
mKIAA0 ILHFKPCGLFGKELHRVEGYIQDKNRKKLFIMYGKWTECLWGIDPASYESFKKQEKRGDQ
..: .. . :..:: . :.. : . ..::: : .. .:
mKIAA0 KVNFIKAKYWSTNAHEIEGTVFDRSGKAVHRLFGKWHESIYCGGASS-------------
730 740 750 760 770
170 180 190 200 210 220
mKIAA0 ARKAKMDDGPEKANSDVPGDVADDVPVAQETVQVIPGSKLLWRINSRPPNSAQMYNFTSF
: .:: : : . :.:.::.:
mKIAA0 -------------------------------------STCVWRANPMPKGYEQYYGFTQF
780 790
230 240 250 260 270 280
mKIAA0 TVSLNELESGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREARKERAKEDA
.. :::.. .. ::::: :.::: :
mKIAA0 ALELNEMDPLSRSLLPPTDTRFRPDQR
800 810 820
>>mKIAA4128 ( 1002 res) mbf00283 (1002 aa)
initn: 586 init1: 240 opt: 267 Z-score: 266.0 bits: 59.1 E(): 1.1e-09
Smith-Waterman score: 566; 35.714% identity (43.568% ungapped) in 294 aa overlap (1-293:725-966)
10 20 30
mKIAA0 ELIREDLGFRFISEQVSHHPPISAFYSEGL
: :::: ::::.:::::::::::: . :
mKIAA4 LVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCE--
700 710 720 730 740 750
40 50 60 70 80 90
mKIAA0 NQDFRFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIE
...: : .: : ::::::.: : ::... : :... :.:.. : :.::.. :. :::
mKIAA4 SKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIE
760 770 780 790 800 810
100 110 120 130 140
mKIAA0 QYGIVEIVNHRTGDK-CILHFKPCGLFGKELHRVEGYIQDKNRKKLFIMYGKWTECLWGI
.:: : . : ... : : : . .......:.: . :.. : . ..::: : :.
mKIAA4 HYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLY--
820 830 840 850 860 870
150 160 170 180 190 200
mKIAA0 DPASYESFKKQEKRGDQARKAKMDDGPEKANSDVPGDVADDVPVAQETVQVIPGSKLLWR
: :..: .::
mKIAA4 ------------------------------------------------CGVAPSAKCIWR
880
210 220 230 240 250 260
mKIAA0 INSRPPNSAQMYNFTSFTVSLNELESGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKER
.: : : .:.:: :.: ::::. .. ::::: :.::: : .:.::.. :. ::.:
mKIAA4 PGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQR
890 900 910 920 930 940
270 280 290 300 310 320
mKIAA0 LEEKQREARKERAKEDAEWRTRWFSPGNNPYTGAPDWLYAGHYFERNFSDCPDIY
.:: :: :. ... : ..:.
mKIAA4 VEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
950 960 970 980 990 1000
>>mKIAA1451 ( 429 res) mth01486 (429 aa)
initn: 315 init1: 245 opt: 258 Z-score: 261.7 bits: 57.1 E(): 2e-09
Smith-Waterman score: 261; 26.667% identity (34.043% ungapped) in 300 aa overlap (11-308:47-283)
10 20 30 40
mKIAA0 ELIREDLGFRFISEQVSHHPPISAFYSEGLNQDFRFHGSI
.:.::::::::::::: . .. : . :::
mKIAA1 PKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSGSI
20 30 40 50 60 70
50 60 70 80 90 100
mKIAA0 YPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNH
: ::.:.:. : .: : .:...: :. : : .... : . .: : :.:. .
mKIAA1 LAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNITCQ
80 90 100 110 120 130
110 120 130 140 150
mKIAA0 RTGDKCILHFKPCGLFGKE--LHRVEGYIQDKNRKKLFIMYGKWTECLWGIDPASYESFK
.:: . ::.:: ..:. .... : .. ... : . :.: : :
mKIAA1 KTGYSAILEFKLKPFLGSSDYVNQISGKLK-LGKEVLATLEGHWDS----------EVFI
140 150 160 170 180
160 170 180 190 200 210
mKIAA0 KQEKRGDQARKAKMDDGPEKANSDVPGDVADDVPVAQETVQVIPGSKLLWRINSRPPNSA
. .:. : ::.. . . :. ::. . .
mKIAA1 N-DKKTD--------------NSEIFWNPTPDIK--------------QWRLIRHTVKFE
190 200 210
220 230 240 250 260 270
mKIAA0 QMYNFTSFTVSLNELESGMEKTLPPTDCRLRPDIRGMENGNMDLASQEKERLEEKQREAR
.. .: : ..: . . :.. : . :.::: ::: ::.:
mKIAA1 EQDDFES-----EKLWQRVTKAINAKD--------------QTEATQEKYVLEEAQRQAA
220 230 240 250
280 290 300 310 320
mKIAA0 KERAKEDAEWRTRWFSPGNNPYTGAPDWLYAGHYFERNFSDCPDIY
..: . :: . : .: :: .: :
mKIAA1 RDRKTKTQEWVCKLFEL--DPLTG--EWHYKFSDTRPWDPLNDMIQFEKDGVIQTKVKHR
260 270 280 290 300 310
>>mKIAA1534 ( 493 res) mph00515 (493 aa)
initn: 215 init1: 176 opt: 210 Z-score: 213.8 bits: 48.4 E(): 9.2e-07
Smith-Waterman score: 210; 40.230% identity (40.230% ungapped) in 87 aa overlap (11-97:139-225)
10 20 30 40
mKIAA0 ELIREDLGFRFISEQVSHHPPISAFYSEGLNQDFRFHGSI
.:.::::::::.:::: . .. : . :::
mKIAA1 PKGIKKPYNPILGETFRCRWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSI
110 120 130 140 150 160
50 60 70 80 90 100
mKIAA0 YPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVHNVILGQLWIEQYGIVEIVNH
: ::.:.:. : : : .:...: :: : : .... : . .: : :..
mKIAA1 TAKSKFYGNSLSALLDGKAKLTFLNRKEEYTLTMPYAHCRGILYGTMTMELGGKVDVFIK
170 180 190 200 210 220
110 120 130 140 150 160
mKIAA0 RTGDKCILHFKPCGLFGKELHRVEGYIQDKNRKKLFIMYGKWTECLWGIDPASYESFKKQ
mKIAA1 EESSGGTELFWTPSEEVRRQRLKRHTVLLEEQSELESERLWQHVTRAIREGDQHKATQEK
230 240 250 260 270 280
324 residues in 1 query sequences
1768693 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:28:20 2006 done: Mon Mar 27 10:28:21 2006
Scan time: 0.540 Display time: 0.060
Function used was FASTA [version 3.4t11 Apr 17, 2002]