FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA4247.ptfa, 326 aa
 vs ./tmplib.26680 library

1768691 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 4.4777+/-0.00372; mu= 13.3193+/- 0.249
 mean_var=70.6317+/-16.076, 0's: 0 Z-trim: 2  B-trim: 0 in 0/36
 Lambda= 0.1526

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0455  ( 795 res)   mbg13653                   ( 795)  698  163 4.9e-41
mKIAA4076  ( 605 res)   mbh01667                   ( 605)  427  103 3.7e-23


>>mKIAA0455  ( 795 res)   mbg13653                        (795 aa)
 initn: 514 init1: 367 opt: 698  Z-score: 829.1  bits: 163.0 E(): 4.9e-41
Smith-Waterman score: 698;  39.048% identity (41.275% ungapped) in 315 aa overlap (11-320:93-395)

                                   10        20        30        40
mKIAA4                     EMAVENNTQRSYSIIPCFIFVELVIMAGTVLLAYYFECTD
                                     : ...::: :::: :.:..:.  :..: ::
mKIAA0 VHTSPGGGLGARQAAGMSAKERPKGKVIKDSVTLLPCFYFVELPILASSVVSLYFLELTD
             70        80        90       100       110       120  

                50        60        70         80        90        
mKIAA4 TFQ-VHIQGFFCQDGDLMKPYPGTEEESFISPLVLYCVLA-ATPTAIIFIGEISMYFIKS
       .:. :: .:: : : .:  ::    .:..  :...   :: : :.  :..::  .:   :
mKIAA0 VFKPVH-SGFSCYDRSLSMPYIEPTQEAI--PFLMLLSLAFAGPAITIMVGEGILYCCLS
             130       140       150         160       170         

      100       110       120       130       140       150        
mKIAA4 TRESLIAEEKMILTGDCCYLSPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFL
        :..  . :  : .: : . : .::: .::.:: .::: .: ....  :. ::. .::::
mKIAA0 KRRNGAGLEPNINAGGCNFNS-FLRRAVRFVGVHVFGLCSTALITDIIQLSTGYQAPYFL
     180       190       200        210       220       230        

      160         170       180        190       200       210     
mKIAA4 TVCQPNYTSTD--CRAHQQFINNGNICTG-DLEVIEKARRSFPSKHAALSIYSALYATMY
       :::.::::: .  :. .. ....  ::.: :: ::...:.::::.::.:. ..:.:..::
mKIAA0 TVCKPNYTSLNVSCKENSYIVED--ICSGSDLTVINSGRKSFPSQHATLAAFAAVYVSMY
      240       250       260         270       280       290      

         220       230       240       250       260       270     
mKIAA4 ITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMC
       ..::. : ::.: ::.: .  .  ... ::.:...:.::  ::  ::..: ..::.::. 
mKIAA0 FNSTL-TDSSKLLKPLLVFTFIICGIICGLTRITQYKNHPVDVYCGFLIGGGIALYLGLY
        300        310       320       330       340       350     

         280       290       300       310       320               
mKIAA4 VVHNFRGTQGSPSKPKPEDPRGVPLMAFPRIESPLETLSAQNHSASMTEVT         
       .: ::  .. :  . . .  :..  .     ..: ..:::.: :..              
mKIAA0 AVGNFLPSEDSMLQHR-DALRSLTDLN----QDPSRVLSAKNGSSGDGIAHTEGILNRNH
         360       370        380           390       400       410

mKIAA0 RDASSLTNLKRANADVEIITPRSPMGKESMVTFSNTLPRANTPSVEDPVRRNASIHASMD
              420       430       440       450       460       470

>>mKIAA4076  ( 605 res)   mbh01667                        (605 aa)
 initn: 275 init1: 275 opt: 427  Z-score: 508.1  bits: 103.2 E(): 3.7e-23
Smith-Waterman score: 427;  38.000% identity (40.426% ungapped) in 200 aa overlap (130-325:22-213)

     100       110       120       130       140       150         
mKIAA4 RESLIAEEKMILTGDCCYLSPLLRRIIRFIGVFAFGLFATDIFVNAGQVVTGHLTPYFLT
                                     :: .::: :: . ... :..::. ::.:::
mKIAA4          TGLGEHPSPLLPSPGLALSSSGVHVFGLCATALVTDVIQLATGYHTPFFLT
                        10        20        30        40        50 

     160         170       180        190       200       210      
mKIAA4 VCQPNYT--STDCRAHQQFINNGNICTG-DLEVIEKARRSFPSKHAALSIYSALYATMYI
       ::.::::  .:.:...  .:.. .::.: : ..: .::..:::.::.:: ..:.:..::.
mKIAA4 VCKPNYTLLGTSCESNP-YITQ-DICSGHDTHAILSARKTFPSQHATLSAFAAVYVSMYF
              60         70         80        90       100         

        220       230       240       250       260       270      
mKIAA4 TSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCV
       ...: . ...: ::.: ..   .: . ::.....::.:  :: :::..:...: .:.  .
mKIAA4 NAVI-SDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHA
     110        120       130       140       150       160        

        280       290        300       310       320               
mKIAA4 VHNFRGTQGSPSKPKPED-PRGVPLMAFPRIESPLETLSAQNHSASMTEVT         
       : ::   :. :..  :   :    : :.   .   :..  ::.:.:  :.          
mKIAA4 VGNF---QAPPAEKVPTPAPAKDALRALT--QRGHESMYQQNKSVSTDELGPPGRLEGVP
      170          180       190         200       210       220   

mKIAA4 RPVAREKTSLGSLKRASVDVDLLAPRSPMGKEGMVTFSNTLPRVSTPSLDDPARRHMTIH
           230       240       250       260       270       280   




326 residues in 1 query   sequences
1768691 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 11:06:22 2006 done: Mon Mar 27 11:06:23 2006
 Scan time:  0.520 Display time:  0.030

Function used was FASTA [version 3.4t11 Apr 17, 2002]