FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA1320.ptfa, 150 aa
vs ./tmplib.26680 library
1768867 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 3.5464+/-0.00388; mu= 15.6758+/- 0.260
mean_var=64.3168+/-14.615, 0's: 0 Z-trim: 15 B-trim: 55 in 1/35
Lambda= 0.1599
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 36, opt: 24, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA0312 ( 2934 res) mbf01960 (2934) 488 122 1.8e-28
mKIAA4011 ( 876 res) mpm01139 ( 876) 481 120 2.7e-28
mKIAA1301 ( 1455 res) mbg18866 (1455) 481 120 3.6e-28
mKIAA0322 ( 1177 res) mbg19003 (1177) 465 116 4.2e-27
mKIAA0093 ( 904 res) mbg10506 ( 904) 464 116 4.2e-27
mKIAA1625 ( 222 res) mbh04778 ( 222) 417 104 3.5e-24
mKIAA0317 ( 826 res) mbg01653 ( 826) 326 84 1.5e-17
mKIAA4216 ( 906 res) mfj70377 ( 906) 315 81 9.4e-17
mKIAA0010 ( 1086 res) mbg01752 (1086) 314 81 1.2e-16
mKIAA1131 ( 1571 res) mth00654 (1571) 264 70 4.5e-13
mKIAA0393 ( 1871 res) mbg13346 (1871) 254 68 2.4e-12
mKIAA1593 ( 1058 res) mpm02342 (1058) 247 66 5.4e-12
mKIAA0032 ( 938 res) mbg05393 ( 938) 222 60 2.8e-10
mKIAA0896 ( 1765 res) mbg01966 (1765) 186 52 1.3e-07
mKIAA0614 ( 1159 res) mbg10347 (1159) 168 48 1.8e-06
>>mKIAA0312 ( 2934 res) mbf01960 (2934 aa)
initn: 485 init1: 398 opt: 488 Z-score: 603.6 bits: 122.0 E(): 1.8e-28
Smith-Waterman score: 488; 51.007% identity (51.351% ungapped) in 149 aa overlap (1-149:2715-2862)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAM
..: ..:.::.: :: .::::.:.. ::.
mKIAA0 ECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEVQEFGVC
2690 2700 2710 2720 2730 2740
40 50 60 70 80 90
mKIAA1 EEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDE
: :::.:..::::..:: :::.:: ..::: ::. :. :::.::. .:: ::..: :
mKIAA0 EVRDLKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFYEIIPKRLISIFTE
2750 2760 2770 2780 2790 2800
100 110 120 130 140 150
mKIAA1 YELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
:::::.::.: ::..: .:::: . :. .. :::::...... : .:. .::::::
mKIAA0 QELELLISGLPTIDIDDLKSNTEYHK-YQSNSIQIQWFWRALRSFDQADRAKFLQFVTGT
2810 2820 2830 2840 2850 2860
mKIAA0 SKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYESFEKLRHMLLLA
2870 2880 2890 2900 2910 2920
>>mKIAA4011 ( 876 res) mpm01139 (876 aa)
initn: 472 init1: 375 opt: 481 Z-score: 600.3 bits: 119.7 E(): 2.7e-28
Smith-Waterman score: 481; 45.946% identity (46.259% ungapped) in 148 aa overlap (2-149:660-806)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAME
.: :. .:.: . :::. :::. ...: ..
mKIAA4 TGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIK
630 640 650 660 670 680
40 50 60 70 80 90
mKIAA1 EVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEY
:::.::.::::..:: ::...:.: :..:... : .::..::. ..: . .: ::
mKIAA4 SHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAK
690 700 710 720 730 740
100 110 120 130 140 150
mKIAA1 ELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
:::.:: :: :::.::: ... : : : . :.:::. :..: .:.:. :::::::
mKIAA4 ELEVLLCGMQEIDLNDWQRHAIYRH-YTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTC
750 760 770 780 790 800
mKIAA4 RLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIE
810 820 830 840 850 860
>>mKIAA1301 ( 1455 res) mbg18866 (1455 aa)
initn: 476 init1: 427 opt: 481 Z-score: 598.0 bits: 120.0 E(): 3.6e-28
Smith-Waterman score: 481; 46.980% identity (47.297% ungapped) in 149 aa overlap (1-149:1238-1385)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAM
..:::. :::: :. :.:::.:. .::: .
mKIAA1 DAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDI-LDLTFTVNEEVFGQI
1210 1220 1230 1240 1250 1260
40 50 60 70 80 90
mKIAA1 EEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDE
: :::::..: ::..:: ::.. ... :. :.. : .....::. . :...::
mKIAA1 TERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDA
1270 1280 1290 1300 1310 1320
100 110 120 130 140 150
mKIAA1 YELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
::::...: :::.::: .:::: .::. . ::.::: .:: ...:.:. :::::::
mKIAA1 RELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGT
1330 1340 1350 1360 1370 1380
mKIAA1 SSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAV
1390 1400 1410 1420 1430 1440
>>mKIAA0322 ( 1177 res) mbg19003 (1177 aa)
initn: 460 init1: 414 opt: 465 Z-score: 579.0 bits: 116.1 E(): 4.2e-27
Smith-Waterman score: 465; 46.309% identity (46.622% ungapped) in 149 aa overlap (1-149:960-1107)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAM
..:::. ::.:.:. :.:::.:. .::: .
mKIAA0 DAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMKDNNITDI-LDLTFTVNEEVFGQV
930 940 950 960 970 980
40 50 60 70 80 90
mKIAA1 EEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDE
: :: ::.. ::..:: ::.. ... :. :.. : .:.:.::. . :...::
mKIAA0 TERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALLRGFYEVVDSRLVSVFDA
990 1000 1010 1020 1030 1040
100 110 120 130 140 150
mKIAA1 YELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
::::...: :::.::: .:::: .::. ::.::: .:: ...:.:. :::::::
mKIAA0 RELELVIAGTAEIDLNDWRNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGT
1050 1060 1070 1080 1090 1100
mKIAA0 SSVPYEGFAALRGSNGLRRFCIEKWGKITSLPRAHTCFNRLDLPPYPSYSMLYEKLLTAV
1110 1120 1130 1140 1150 1160
>>mKIAA0093 ( 904 res) mbg10506 (904 aa)
initn: 428 init1: 428 opt: 464 Z-score: 578.9 bits: 115.7 E(): 4.2e-27
Smith-Waterman score: 464; 46.622% identity (47.260% ungapped) in 148 aa overlap (2-149:688-833)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAME
.:.:::.:: ..: .: : .. ..:: .
mKIAA0 GFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTEL--DLRFIIDEELFGQTH
660 670 680 690 700 710
40 50 60 70 80 90
mKIAA1 EVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEY
. :: ::. :.::..:: ::. :: . :.. :: :. :: .:: .:: .::..:::
mKIAA0 QHELKTGGSEIVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDEN
720 730 740 750 760 770
100 110 120 130 140 150
mKIAA1 ELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
:::::. :. ..::::: ..:.: .:: . ::.:::..: . .:.:. :::::::
mKIAA0 ELELLMCGLGDVDVNDWREHTKYKNGYSMNHQVIHWFWKAVWMMDSEKRIRLLQFVTGTS
780 790 800 810 820 830
mKIAA0 RVPMNGFAELYGSNGPQSFTVEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIE
840 850 860 870 880 890
>>mKIAA1625 ( 222 res) mbh04778 (222 aa)
initn: 412 init1: 278 opt: 417 Z-score: 526.5 bits: 104.0 E(): 3.5e-24
Smith-Waterman score: 417; 43.624% identity (44.218% ungapped) in 149 aa overlap (1-149:61-207)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAM
:.: :::.:::. . :. :: :: ..:: .
mKIAA1 NGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPV-LDHTFCVEHNAFGRI
40 50 60 70 80
40 50 60 70 80 90
mKIAA1 EEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDE
. :::.: .. ::..:: :::.: .. :. :.:. :. :. .::. .:: :.. ::.
mKIAA1 LQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ
90 100 110 120 130 140
100 110 120 130 140 150
mKIAA1 YELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
::::...:. .::.::: .::. .. ...:::..:: . .:.:. :::::::
mKIAA1 KELELIIGGLDKIDLNDWKSNTRLKHCVA-DSNIVRWFWQAVETFDEERRARLLQFVTGS
150 160 170 180 190 200
mKIAA1 TRVPLQGFKALQGD
210 220
>>mKIAA0317 ( 826 res) mbg01653 (826 aa)
initn: 303 init1: 204 opt: 326 Z-score: 407.2 bits: 83.9 E(): 1.5e-17
Smith-Waterman score: 326; 37.162% identity (38.462% ungapped) in 148 aa overlap (5-149:615-760)
10 20 30
mKIAA1 KNLQWILDNDISDLGLELTFSVET-DVFGAMEE-
.::.::.:.. ::.:. : . : ...
mKIAA0 RSFLAQIIGLRMHYKYFETDDPEFYKSKVCFILNNDMSEM--ELVFAEEKYNKSGQLDKI
590 600 610 620 630 640
40 50 60 70 80 90
mKIAA1 VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE
: : ::.. ::. :: :..:... :.. .. ... ::.:.. ..: .:. .::: :
mKIAA0 VELMTGGAQTPVTNANKIFYLNLLAQYRLASQVKEEVEHFLKGLNELVPENLLAIFDENE
650 660 670 680 690 700
100 110 120 130 140 150
mKIAA1 LELLLSGMPEIDVNDWIKNTEYTSG-YEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
::::. : .:.:.:. .. ..: .. .. :..::: :: ..:::: . ::::.::
mKIAA0 LELLMCGTGDINVSDFKAHAVVVGGSWHFREKVMRWFWAVVSSLTQEELARLLQFTTGSS
710 720 730 740 750 760
mKIAA0 QLPPGGFAALCPSFQIIAAPTHSTLPTAHTCFNQLCLPTYDSYEEVHRMLQLAISEGCEG
770 780 790 800 810 820
>>mKIAA4216 ( 906 res) mfj70377 (906 aa)
initn: 305 init1: 180 opt: 315 Z-score: 393.1 bits: 81.4 E(): 9.4e-17
Smith-Waterman score: 315; 38.971% identity (39.552% ungapped) in 136 aa overlap (16-149:707-842)
10 20 30 40
mKIAA1 KNLQWILDNDISDLGLELTFSV-ETDVFGAMEEVPLKPGGGSILV
. .::.. .::.:: :: .: .: .
mKIAA4 GTFRDLGDSHPVLYQSLKDLLEYEGSVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPI
680 690 700 710 720 730
50 60 70 80 90 100
mKIAA1 TQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPS-LIQLFDEYELELLLSGMPEI
:..:. :.:.: .. ...... :..:: .:::: : : :: :.:::. : ..
mKIAA4 TNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNL
740 750 760 770 780 790
110 120 130 140 150
mKIAA1 DVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
: . ..::: .:: ::. ::. :::.:...:.:.. :.:::.::
mKIAA4 DFQALEETTEYDGGYTRESVVIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKM
800 810 820 830 840 850
mKIAA4 IIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML
860 870 880 890 900
>>mKIAA0010 ( 1086 res) mbg01752 (1086 aa)
initn: 281 init1: 165 opt: 314 Z-score: 391.1 bits: 81.3 E(): 1.2e-16
Smith-Waterman score: 314; 36.424% identity (37.671% ungapped) in 151 aa overlap (1-148:871-1019)
10 20
mKIAA1 KNLQWI--LDNDISDLGLELTFSVETDVFG
.:: .. ..:. .:::. :.: .. .:
mKIAA0 PFAGFFLSKLLGTSADVDIHHLASLDPEVYRNLLFLKSYEEDVEELGLN--FTVVNNDLG
850 860 870 880 890
30 40 50 60 70 80
mKIAA1 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
. : :: :: .: :: :. :..::.. :... :.:. :: ::. . ...:
mKIAA0 EAQVVELKFGGKDIPVTGANRIAYIHLVADYRLNKQIRPHCLAFRQGLANVVSLEWLRMF
900 910 920 930 940 950
90 100 110 120 130 140
mKIAA1 DEYELELLLSGMP-EIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFV
:. :...:.:: ....: . :.:..:: . :::. ::.::: .:.::. ::.::
mKIAA0 DQQEIQVLISGAQVPVSLEDLKSFTNYSGGYSADHPVIKIFWRVVEGFTDEEKRKLLKFV
960 970 980 990 1000 1010
150
mKIAA1 TGR
:.
mKIAA0 TSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDEALLRSKLLYAIE
1020 1030 1040 1050 1060 1070
>>mKIAA1131 ( 1571 res) mth00654 (1571 aa)
initn: 232 init1: 121 opt: 264 Z-score: 327.1 bits: 70.0 E(): 4.5e-13
Smith-Waterman score: 264; 34.752% identity (35.507% ungapped) in 141 aa overlap (11-149:1366-1505)
10 20 30 40
mKIAA1 KNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGG
: ::::.. : . ..: . : :::.:
mKIAA1 GNKSLSEDEKNTKLQELVLRNPSGSGPPLSIEDLGLNFQFCPSSRIYG-FTAVDLKPSGE
1340 1350 1360 1370 1380 1390
50 60 70 80 90 100
mKIAA1 SILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGM
. ..:..: :::.:. .. : .:: :..:: .::. .: .. :.. :....: :
mKIAA1 DEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSSFSHEEVQMILCGN
1400 1410 1420 1430 1440 1450
110 120 130 140 150
mKIAA1 --PEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGR
: ..: :. :: :: :..: . : .:. ....:: .:::.::
mKIAA1 QSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGL
1460 1470 1480 1490 1500 1510
mKIAA1 ANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRERLLAATMEKGFHLN
1520 1530 1540 1550 1560 1570
150 residues in 1 query sequences
1768867 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:40:55 2006 done: Mon Mar 27 10:40:56 2006
Scan time: 0.330 Display time: 0.070
Function used was FASTA [version 3.4t11 Apr 17, 2002]