FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0321.ptfa, 2548 aa
vs ./tmplib.26680 library
1766469 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 5.5853+/-0.00543; mu= 19.8836+/- 0.362
mean_var=140.7961+/-32.727, 0's: 0 Z-trim: 14 B-trim: 136 in 1/35
Lambda= 0.1081
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 44, opt: 32, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA1362 ( 1407 res) mia41047 (1407) 261 54 4.7e-07
mKIAA0305 ( 1536 res) mbg08215 (1536) 235 50 8.1e-06
mKIAA1643 ( 950 res) mbh04344 ( 950) 227 48 1.4e-05
mKIAA0993 ( 646 res) mbg00079 ( 646) 210 45 7.2e-05
mKIAA4239 ( 1059 res) mfj24184 (1059) 211 46 8.7e-05
mKIAA4212 ( 600 res) mbg08227 ( 600) 201 44 0.00018
mKIAA1537 ( 628 res) mbg18407 ( 628) 200 44 0.00021
mKIAA1255 ( 176 res) mbg10338 ( 176) 187 41 0.00039
mKIAA0647 ( 1186 res) mbg01911 (1186) 188 42 0.0011
mFLJ00274 ( 1530 res) mpf00869 (1530) 183 42 0.0022
mKIAA1435 ( 411 res) mbp03169 ( 411) 172 39 0.0033
mKIAA0981 ( 2117 res) mib04069 (2117) 177 41 0.0052
mKIAA1589 ( 775 res) mbh04724 ( 775) 168 39 0.0075
>>mKIAA1362 ( 1407 res) mia41047 (1407 aa)
initn: 265 init1: 190 opt: 261 Z-score: 219.1 bits: 53.9 E(): 4.7e-07
Smith-Waterman score: 261; 30.435% identity (32.450% ungapped) in 161 aa overlap (1759-1912:1132-1289)
1730 1740 1750 1760 1770 1780
mKIAA0 LLSRYAGKALDLPYPLREKRSDSMIHLQEPVHQASDSETLSRSSSAEFSAAAAPGSALVR
.... : :: ::.:: . :. ..
mKIAA1 SGMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSAAERDDWLEAISSSIE
1110 1120 1130 1140 1150 1160
1790 1800 1810 1820 1830 1840
mKIAA0 SPSPKE------RAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRH
. :. :.. . . : : : : :.:: ..::.: : ::. :::
mKIAA1 EYAKKRITFCPSRSLDEDSERKEEVSPLGAKA-PIWIPDTRATMCMICTSE-FTLTWRRH
1170 1180 1190 1200 1210
1850 1860 1870 1880 1890 1900
mKIAA0 HCRRCGRLVCGSCSTKKMVVEGFRENPTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNES
::: ::..:: .::..:. .. .. . .:::..:.. .: . :: . : . :. :
mKIAA1 HCRACGKIVCQACSSNKYGLDYLKGQLARVCEHCFQELQKLDHQLSP-RVGSPGNHKSPS
1220 1230 1240 1250 1260 1270
1910 1920 1930 1940 1950 1960
mKIAA0 PPYSAVVR-VPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGH
:.:.. .:.
mKIAA1 SALSSVLHSIPSGRKQKKIPAALKEVSANTEDSTMSGYLYRSKGSKKPWKHLWFVIKNKV
1280 1290 1300 1310 1320 1330
>>mKIAA0305 ( 1536 res) mbg08215 (1536 aa)
initn: 246 init1: 127 opt: 235 Z-score: 196.8 bits: 49.9 E(): 8.1e-06
Smith-Waterman score: 235; 31.206% identity (33.846% ungapped) in 141 aa overlap (1764-1901:692-824)
1740 1750 1760 1770 1780 1790
mKIAA0 AGKALDLPYPLREKRSDSMIHLQEPVHQASDSETLSRSSSAEFSAAAAPGSALVRSPSPK
::.. :. .. . ::..: . .
mKIAA0 NKPDVVDVPESEPCTANATAVSTCSADHIPDSQVSFNSNYIDIESNFEDGSSFV---TAN
670 680 690 700 710
1800 1810 1820 1830 1840 1850
mKIAA0 ERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHHCRRCGRLVCG
. ..:... .: . :. :::: :: :. .::. .:::::: ::.. ::
mKIAA0 KDSLPENKRKESLVLGQKQPT---WVPDSEAPNCM-NCQVKFTFTKRRHHCRACGKVFCG
720 730 740 750 760 770
1860 1870 1880 1890 1900 1910
mKIAA0 SCSTKKMVVEGFRENPTRVCDQCYSYYNKDTPEE---SPCQSEVPDSAKNESPPYSAVVR
: ..: .. . :. .::: :: :: : :: : . .. .::
mKIAA0 VCCNRKCKLQ-YLEKEARVCVICYETINKAQAFERMMSPGGSCLKSNHSNECATDQPLQE
780 790 800 810 820 830
1920 1930 1940 1950 1960 1970
mKIAA0 VPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRL
mKIAA0 TQTSSTPSPTTLPISALKQPNVEGPCSKEQKRVWFADGILPNGEVADTTKLSSGSKRCSD
840 850 860 870 880 890
>>mKIAA1643 ( 950 res) mbh04344 (950 aa)
initn: 191 init1: 119 opt: 227 Z-score: 192.3 bits: 48.4 E(): 1.4e-05
Smith-Waterman score: 232; 29.677% identity (33.577% ungapped) in 155 aa overlap (1727-1880:802-939)
1700 1710 1720 1730 1740 1750
mKIAA0 NMKVDWATTAVQTLHQLLAGQDIGFTLDEVDSLLSRYAGKALDLPYPLREKRSDSMIHLQ
:.: . ::. :: :. ......
mKIAA1 PMATREKIRSRFHGSHDLIHRLFVCISGVADQLQTNYAS---DLRSILK-----TLFEVM
780 790 800 810 820
1760 1770 1780 1790 1800 1810
mKIAA0 EPVHQASDSETLSRSSSAEFSAAAAPGSALVRSPSPKERAFPQTQPPVEFVPPETPPARD
...:.: :.. ... ::: . .. : .: : .:. .: : ::
mKIAA1 ATKPETDDKEKLKKVTQTLRSAALEDCALCQETVSSSELA-AKTRDG-DF---EDPP---
830 840 850 860 870
1820 1830 1840 1850 1860 1870
mKIAA0 QWVPDETESVCMVCCREHFTMFNRRHHCRRCGRLVCGSCSTKKMVVEGFRE-NPTRVCDQ
.:::::. . : . :. ::.. :.:::: ::.. :. ::... . . . .:.::: .
mKIAA1 EWVPDEACGFC-TSCKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH
880 890 900 910 920 930
1880 1890 1900 1910 1920 1930
mKIAA0 CYSYYNKDTPEESPCQSEVPDSAKNESPPYSAVVRVPKATEVEWILSLSEEENELVRSEF
:: ..
mKIAA1 CYMFHVTPFYSDKTGM
940 950
>>mKIAA0993 ( 646 res) mbg00079 (646 aa)
initn: 128 init1: 128 opt: 210 Z-score: 179.8 bits: 45.5 E(): 7.2e-05
Smith-Waterman score: 210; 38.462% identity (40.000% ungapped) in 78 aa overlap (1814-1889:567-643)
1790 1800 1810 1820 1830 1840
mKIAA0 SALVRSPSPKERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHH
: :.:: :: . : : .:.. .::::
mKIAA0 GVSKDHSRILVGDSRGRVFSWSVSDQPGRSAADHWVKDEGGDSCS-GCSVRFSLTERRHH
540 550 560 570 580 590
1850 1860 1870 1880 1890 1900
mKIAA0 CRRCGRLVCGSCSTKKMVVEGFR-ENPTRVCDQCY-SYYNKDTPEESPCQSEVPDSAKNE
:: ::.: : .:: . .. .. .:.:::..:: : .. :..:
mKIAA0 CRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCYYSLQHERGAEDGPRNC
600 610 620 630 640
1910 1920 1930 1940 1950 1960
mKIAA0 SPPYSAVVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGH
>>mKIAA4239 ( 1059 res) mfj24184 (1059 aa)
initn: 262 init1: 165 opt: 211 Z-score: 178.3 bits: 45.9 E(): 8.7e-05
Smith-Waterman score: 211; 29.661% identity (32.710% ungapped) in 118 aa overlap (1786-1900:798-907)
1760 1770 1780 1790 1800 1810
mKIAA0 QEPVHQASDSETLSRSSSAEFSAAAAPGSALVRSPSPKERAFPQTQPPVEFVPPETPPAR
:. : . .. : ..: :.. : :
mKIAA4 QARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIR
770 780 790 800 810 820
1820 1830 1840 1850 1860 1870
mKIAA0 DQWVPDETESVCMVCCREHFTMFNRRHHCRRCGRLVCGSCS--TKKMVVEGFRENPTRVC
.. : ..:: : . .. .:::::. ::..:::.:: ... .. : : :::
mKIAA4 EKEV-----TMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSN--RVC
830 840 850 860 870 880
1880 1890 1900 1910 1920 1930
mKIAA0 DQCYSYYNKDTPEESP-CQSEVPDSAKNESPPYSAVVRVPKATEVEWILSLSEEENELVR
.:: . .: :: :....:. ..
mKIAA4 TDCYVALH-GAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKA
890 900 910 920 930
>>mKIAA4212 ( 600 res) mbg08227 (600 aa)
initn: 146 init1: 104 opt: 201 Z-score: 172.5 bits: 44.0 E(): 0.00018
Smith-Waterman score: 201; 34.426% identity (35.593% ungapped) in 61 aa overlap (1818-1878:531-589)
1790 1800 1810 1820 1830 1840
mKIAA0 RSPSPKERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHHCRRC
:. :. . : : .. :.. :.:::: :
mKIAA4 ALQEMGLHLSQSKLKMEDIKEVNKALKGHTWLKDDEATHCKQCEKD-FSISRRKHHCRNC
510 520 530 540 550
1850 1860 1870 1880 1890 1900
mKIAA0 GRLVCGSCSTKKMVVEGFRENPTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNESPPYSA
:.. :..::...... .. .:.::::.:..
mKIAA4 GHIFCNTCSSNELALPSY-PKPVRVCDSCHTLLLQRCSSTAS
560 570 580 590 600
1910 1920 1930 1940 1950 1960
mKIAA0 VVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHC
>>mKIAA1537 ( 628 res) mbg18407 (628 aa)
initn: 169 init1: 96 opt: 200 Z-score: 171.5 bits: 43.9 E(): 0.00021
Smith-Waterman score: 223; 23.009% identity (27.660% ungapped) in 678 aa overlap (1277-1895:6-628)
1250 1260 1270 1280 1290
mKIAA0 LCLSRQSQQASSLLTHLGMLAREHASHLLDGLPLSTLGSPRP-------SENPSAERKSH
: :. .:: : ...:.: ....
mKIAA1 PPRACGELLTRSASPCPARTAAMATKDPTAVERAN
10 20 30
1300 1310 1320 1330 1340
mKIAA0 --SSPKDSLPAFTASALAFLKSRSK--------ILAMVACLRTSRGTKVSKPGLSW-KEL
. : :. .. :::.: .. .. ...: ::. .: : : ::. : .
mKIAA1 LLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLK--HGLKGRKSFLSYNKTI
40 50 60 70 80 90
1350 1360 1370 1380 1390 1400
mKIAA0 RGRREAPLT-AEKVAQECEHL---LEQFPVFEAAL--LANWEPLQQASEPKQSLAASLCG
: :: .::. : :.. ....: ... : : : .. . :
mKIAA1 WG----PLELVEKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLII
100 110 120 130 140
1410 1420 1430 1440 1450
mKIAA0 QANLSTVLLGLHSSLALDILTEAFEGALVARDWPRALQLID----VYGQDLD------DL
: .: . . : :: .. : :::... .:..:: : :.::: :.
mKIAA1 QRELLSEFYEYH---AL-MMEE--EGAVIV-GLLVGLNVIDANLCVKGEDLDSQVGVIDF
150 160 170 180 190 200
1460 1470 1480 1490 1500
mKIAA0 SIV---------QDSVLTCAAVCDKEGWQYLFPVKDASLRSQLALRFVDKWPLESC--LE
:. .. . ::. :.... . . : :.: : ::. . .:
mKIAA1 SMYLKNEEEIGNKERNVQIAAILDQKNYVEELNRQLNSTVSSLHSR-VDSLEKSNTKLIE
210 220 230 240 250 260
1510 1520 1530 1540 1550
mKIAA0 ILAYCVSDMA-VQEE---LKSELQRKLMELRVYQKILGLQDPPVWCDWQTLRSCCAEDPS
:: ... .::: :.:: . ::. : . .. .. : . :: .
mKIAA1 ELAIAKNNIIKLQEENHQLRSENELILMRTRQHLEVTKVD---VETELQTYKHS-----R
270 280 290 300 310
1560 1570 1580 1590 1600 1610
mKIAA0 AVMDMMLDSQEYELCEEWGRLYPIPREHLVSLHHKH----LLHLLERSEHDKA---LQLL
.: : .. . .: .: . : :.. :: ..:::.. :.: . :
mKIAA1 QGLDEMYNDARRQLRDESQLRQDVENELSVQVGMKHEMELAMKLLEKDIHEKQDTLIGLR
320 330 340 350 360 370
1620 1630 1640 1650 1660
mKIAA0 QRIPD-PTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTTDRHREIQALYMGSKVL
:.. . .. .:. .: .. .: .. . : . :. :. : : : .. :.
mKIAA1 QQLEEVKAINIEMYQRLQGSEDGLKEKNEIIARLEEKTNKITTAMRQLE-QRLQQAEKAQ
380 390 400 410 420 430
1670 1680 1690 1700 1710 1720
mKIAA0 LTLPEQHRASYAR--LSSSPLLMLEQLLMNMKVDWATTAVQTLHQLLAGQDIGFTLDEVD
: . .::. ::.: : : ...: : : :: . : :
mKIAA1 KE-AEAEDEKYAQECLSQSDSL---QRQISQKE-------QQLVQLETDLKIE---KEWR
440 450 460 470
1730 1740 1750 1760 1770 1780
mKIAA0 SLLSRYAGKALDLPYPLREKRSDSMIHLQEPVHQASDSETLSRSSSAEFSAAAAPGSALV
. :.. : :. ::.. . . .: .. .... :.: . . .: :: :
mKIAA1 QTLQEDLQKEKDVLSHLRHETQKVISLKKEFLNLQDENQQLKRIYQEQEQALQELGSKLC
480 490 500 510 520 530
1790 1800 1810 1820 1830 1840
mKIAA0 RSPSPKERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHHCRRC
.: . .. .: :. :. . : .: .: :.. .:.:::: :
mKIAA1 ESKLKIDDIKEANKALQGLV----------WLKDKDATHCKLCEKE-FSLSKRKHHCRNC
540 550 560 570 580
1850 1860 1870 1880 1890 1900
mKIAA0 GRLVCGSCSTKKMVVEGFRENPTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNESPPYSA
:.. :..:: ... . . .:.::::.:... . :.:..:
mKIAA1 GEIFCNACSDNELPLPS-SPKPVRVCDSCHAMLIQR------CSSNMP
590 600 610 620
1910 1920 1930 1940 1950 1960
mKIAA0 VVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHC
>>mKIAA1255 ( 176 res) mbg10338 (176 aa)
initn: 161 init1: 118 opt: 187 Z-score: 166.5 bits: 41.2 E(): 0.00039
Smith-Waterman score: 187; 47.917% identity (48.936% ungapped) in 48 aa overlap (1831-1877:120-167)
1810 1820 1830 1840 1850 1860
mKIAA0 QPPVEFVPPETPPARDQWVPDETESVCMVCCREHFTMFNRRHHCRRCGRLVCGSCSTKKM
: .: . .:.::::.::::.: .::::..
mKIAA1 YQVATKQLLFRLLDMLSKEPPWCDGSNCYECTAKFGVTTRKHHCRHCGRLLCHKCSTKEI
90 100 110 120 130 140
1870 1880 1890 1900 1910
mKIAA0 VVEGFREN-PTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNESPPYSAVVRVPKATEVEW
. : : :.:::. :..
mKIAA1 PIIKFDLNKPVRVCNICFDVLTLGGVS
150 160 170
>>mKIAA0647 ( 1186 res) mbg01911 (1186 aa)
initn: 227 init1: 110 opt: 188 Z-score: 158.4 bits: 42.4 E(): 0.0011
Smith-Waterman score: 188; 40.000% identity (42.623% ungapped) in 65 aa overlap (1817-1879:1101-1163)
1790 1800 1810 1820 1830 1840
mKIAA0 VRSPSPKERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVC-CREHFTMFNRRHHCR
.::::. : :. : :. : . .::::::
mKIAA0 DTEDFGSDHSEDCLSEASWEPVDKKETEVTRWVPDHMASHCFNCDCE--FWLAKRRHHCR
1080 1090 1100 1110 1120
1850 1860 1870 1880 1890 1900
mKIAA0 RCGRLVC-GSCSTKKMVVEGFRENPTRVCDQCYSYYNKDTPEESPCQSEVPDSAKNESPP
:: . : : : : . . .:. ::..:: .
mKIAA0 NCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCYEHIQVSRARELMSQHLKKPIATASS
1130 1140 1150 1160 1170 1180
1910 1920 1930 1940 1950 1960
mKIAA0 YSAVVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLI
>>mFLJ00274 ( 1530 res) mpf00869 (1530 aa)
initn: 150 init1: 150 opt: 183 Z-score: 153.0 bits: 41.8 E(): 0.0022
Smith-Waterman score: 183; 32.967% identity (36.585% ungapped) in 91 aa overlap (1819-1902:1307-1395)
1790 1800 1810 1820 1830 1840
mKIAA0 SPSPKERAFPQTQPPVEFVPPETPPARDQWVPDETESVCMVC-CREHFTMFNRRHHCRRC
:: .:: : : :.. :::::. :
mFLJ00 YKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGC--DFSLTVRRHHCHAC
1280 1290 1300 1310 1320 1330
1850 1860 1870 1880 1890 1900
mKIAA0 GRLVCGSCSTKKMVVEGFRENPTRVCDQCY---SYYNKDTP---EESPCQSEVPDSAKNE
:..:: .:: .:. .. ... ..::: :. . : .: .: : . : :..
mFLJ00 GKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGSMRERPVSMSFPLSSSRF
1340 1350 1360 1370 1380 1390
1910 1920 1930 1940 1950 1960
mKIAA0 SPPYSAVVRVPKATEVEWILSLSEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGH
:
mFLJ00 SSGSALSSVFQSISPSTFKKQKKVPSALSEVAASGEGSAISGYLSRCKSGKRRWKKLWLV
1400 1410 1420 1430 1440 1450
2548 residues in 1 query sequences
1766469 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:17:38 2006 done: Mon Mar 27 10:17:41 2006
Scan time: 1.740 Display time: 0.810
Function used was FASTA [version 3.4t11 Apr 17, 2002]