# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mbj01161.fasta.nr -Q ../query/mKIAA0593.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
mKIAA0593, 731 aa
vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library
2727779818 residues in 7921681 sequences
statistics sampled from 60000 to 7914691 sequences
Expectation_n fit: rho(ln(x))= 5.8508+/-0.000192; mu= 10.1276+/- 0.011
mean_var=99.0231+/-18.912, 0's: 35 Z-trim: 57 B-trim: 283 in 1/64
Lambda= 0.128886
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 38, opt: 26, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7921681)
gi|74186901|dbj|BAE20510.1| unnamed protein produc (1241) 4746 893.5 0
gi|148683837|gb|EDL15784.1| mCG12704 [Mus musculus (1948) 4746 893.6 0
gi|81910189|sp|Q5SWW4.1|MED13_MOUSE RecName: Full= (2171) 4746 893.7 0
gi|149053743|gb|EDM05560.1| thyroid hormone recept (2040) 4698 884.7 0
gi|73966750|ref|XP_537704.2| PREDICTED: similar to (2182) 4553 857.8 0
gi|4530437|gb|AAD22032.1| thyroid hormone receptor (2174) 4520 851.7 0
gi|119571823|gb|EAW51438.1| thyroid hormone recept (2174) 4520 851.7 0
gi|166214951|sp|Q9UHV7.2|MED13_HUMAN RecName: Full (2174) 4520 851.7 0
gi|109114565|ref|XP_001110128.1| PREDICTED: mediat (2174) 4517 851.1 0
gi|114669769|ref|XP_001138050.1| PREDICTED: mediat (2188) 4516 850.9 0
gi|194217212|ref|XP_001500884.2| PREDICTED: mediat (2165) 4499 847.7 0
gi|194675789|ref|XP_603205.4| PREDICTED: similar t (2332) 4491 846.3 0
gi|126307412|ref|XP_001362355.1| PREDICTED: hypoth (2172) 4342 818.6 0
gi|149635568|ref|XP_001509907.1| PREDICTED: simila (2170) 4220 795.9 0
gi|109114567|ref|XP_001110078.1| PREDICTED: mediat (1991) 4218 795.5 0
gi|118100310|ref|XP_415884.2| PREDICTED: similar t (2225) 4155 783.8 0
gi|224076629|ref|XP_002199236.1| PREDICTED: mediat (2179) 4122 777.6 0
gi|67971682|dbj|BAE02183.1| unnamed protein produc ( 611) 3049 577.7 4.5e-162
gi|224071919|ref|XP_002196121.1| PREDICTED: mediat (2206) 2807 533.1 4.1e-148
gi|118098868|ref|XP_415317.2| PREDICTED: similar t (2195) 2759 524.2 2e-145
gi|189528813|ref|XP_001921335.1| PREDICTED: simila (1951) 2188 418.0 1.7e-113
gi|189528775|ref|XP_001918662.1| PREDICTED: hypoth (2102) 2188 418.0 1.8e-113
gi|166233815|sp|A2VCZ5.1|MD13L_DANRE RecName: Full (2102) 2188 418.0 1.8e-113
gi|49257394|gb|AAH72653.1| Med13l protein [Mus mus (1879) 2065 395.1 1.2e-106
gi|149720623|ref|XP_001489783.1| PREDICTED: mediat (2190) 2056 393.5 4.5e-106
gi|6453436|emb|CAB61363.1| hypothetical protein [H (1908) 2046 391.6 1.5e-105
gi|51476392|emb|CAH18186.1| hypothetical protein [ (2069) 2046 391.6 1.6e-105
gi|119618487|gb|EAW98081.1| thyroid hormone recept (2195) 2046 391.6 1.6e-105
gi|74749769|sp|Q71F56.1|MD13L_HUMAN RecName: Full= (2210) 2046 391.6 1.6e-105
gi|73995266|ref|XP_534693.2| PREDICTED: similar to (2280) 2044 391.3 2.2e-105
gi|109098865|ref|XP_001112106.1| PREDICTED: simila (2210) 2042 390.9 2.7e-105
gi|10435895|dbj|BAB14697.1| unnamed protein produc (1111) 2036 389.5 3.5e-105
gi|30353895|gb|AAH52320.1| Med13l protein [Mus mus (1125) 2022 386.9 2.2e-104
gi|149063479|gb|EDM13802.1| thyroid hormone recept (1374) 2023 387.2 2.2e-104
gi|148687845|gb|EDL19792.1| thyroid hormone recept (2050) 2022 387.1 3.4e-104
gi|38036201|gb|AAR08419.1| thyroid hormone recepto (2203) 2022 387.2 3.6e-104
gi|83305883|sp|Q6JPI3.2|MD13L_MOUSE RecName: Full= (2207) 2022 387.2 3.6e-104
gi|146134449|ref|NP_766012.3| thyroid hormone rece (2207) 2022 387.2 3.6e-104
gi|119909346|ref|XP_595505.3| PREDICTED: similar t (2209) 2019 386.6 5.3e-104
gi|126324386|ref|XP_001365474.1| PREDICTED: simila (2199) 2018 386.4 6e-104
gi|126324384|ref|XP_001365407.1| PREDICTED: simila (2201) 2018 386.4 6e-104
gi|47210173|emb|CAF90589.1| unnamed protein produc (2253) 1882 361.1 2.5e-96
gi|47223584|emb|CAF99193.1| unnamed protein produc (1986) 1641 316.3 7e-83
gi|47216840|emb|CAG02731.1| unnamed protein produc (2163) 1433 277.6 3.3e-71
gi|6808448|emb|CAB70855.1| hypothetical protein [H ( 409) 1331 258.1 4.8e-66
gi|210117040|gb|EEA64780.1| hypothetical protein B (1251) 1333 258.9 8.6e-66
gi|210117029|gb|EEA64769.1| hypothetical protein B (1245) 1331 258.5 1.1e-65
gi|47195883|emb|CAF88983.1| unnamed protein produc ( 278) 1177 229.3 1.5e-57
gi|115745092|ref|XP_001203054.1| PREDICTED: simila (1127) 1179 230.2 3.3e-57
gi|157016223|gb|EAA11333.5| AGAP006436-PA [Anophel (2679) 1154 225.8 1.6e-55
>>gi|74186901|dbj|BAE20510.1| unnamed protein product [M (1241 aa)
initn: 4746 init1: 4746 opt: 4746 Z-score: 4767.3 bits: 893.5 E(): 0
Smith-Waterman score: 4746; 99.028% identity (99.306% similar) in 720 aa overlap (12-731:380-1099)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|741 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
350 360 370 380 390 400
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
410 420 430 440 450 460
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
470 480 490 500 510 520
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
530 540 550 560 570 580
230 240 250 260 270 280
mKIAA0 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
590 600 610 620 630 640
290 300 310 320 330 340
mKIAA0 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
650 660 670 680 690 700
350 360 370 380 390 400
mKIAA0 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
710 720 730 740 750 760
410 420 430 440 450 460
mKIAA0 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
770 780 790 800 810 820
470 480 490 500 510 520
mKIAA0 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
830 840 850 860 870 880
530 540 550 560 570 580
mKIAA0 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
890 900 910 920 930 940
590 600 610 620 630 640
mKIAA0 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
950 960 970 980 990 1000
650 660 670 680 690 700
mKIAA0 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
1010 1020 1030 1040 1050 1060
710 720 730
mKIAA0 TGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::::::::::::
gi|741 TGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQP
1070 1080 1090 1100 1110 1120
>>gi|148683837|gb|EDL15784.1| mCG12704 [Mus musculus] (1948 aa)
initn: 4746 init1: 4746 opt: 4746 Z-score: 4764.6 bits: 893.6 E(): 0
Smith-Waterman score: 4746; 99.028% identity (99.306% similar) in 720 aa overlap (12-731:1087-1806)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|148 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1060 1070 1080 1090 1100 1110
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
1120 1130 1140 1150 1160 1170
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
1180 1190 1200 1210 1220 1230
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
1240 1250 1260 1270 1280 1290
230 240 250 260 270 280
mKIAA0 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
1300 1310 1320 1330 1340 1350
290 300 310 320 330 340
mKIAA0 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
1360 1370 1380 1390 1400 1410
350 360 370 380 390 400
mKIAA0 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
1420 1430 1440 1450 1460 1470
410 420 430 440 450 460
mKIAA0 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
1480 1490 1500 1510 1520 1530
470 480 490 500 510 520
mKIAA0 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
1540 1550 1560 1570 1580 1590
530 540 550 560 570 580
mKIAA0 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
1600 1610 1620 1630 1640 1650
590 600 610 620 630 640
mKIAA0 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
1660 1670 1680 1690 1700 1710
650 660 670 680 690 700
mKIAA0 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
1720 1730 1740 1750 1760 1770
710 720 730
mKIAA0 TGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::::::::::::
gi|148 TGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQP
1780 1790 1800 1810 1820 1830
>>gi|81910189|sp|Q5SWW4.1|MED13_MOUSE RecName: Full=Medi (2171 aa)
initn: 4746 init1: 4746 opt: 4746 Z-score: 4764.0 bits: 893.7 E(): 0
Smith-Waterman score: 4746; 99.028% identity (99.306% similar) in 720 aa overlap (12-731:1310-2029)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|819 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1280 1290 1300 1310 1320 1330
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
1340 1350 1360 1370 1380 1390
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
1400 1410 1420 1430 1440 1450
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
1460 1470 1480 1490 1500 1510
230 240 250 260 270 280
mKIAA0 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
1520 1530 1540 1550 1560 1570
290 300 310 320 330 340
mKIAA0 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
1580 1590 1600 1610 1620 1630
350 360 370 380 390 400
mKIAA0 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
1640 1650 1660 1670 1680 1690
410 420 430 440 450 460
mKIAA0 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
1700 1710 1720 1730 1740 1750
470 480 490 500 510 520
mKIAA0 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
1760 1770 1780 1790 1800 1810
530 540 550 560 570 580
mKIAA0 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
1820 1830 1840 1850 1860 1870
590 600 610 620 630 640
mKIAA0 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
1880 1890 1900 1910 1920 1930
650 660 670 680 690 700
mKIAA0 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|819 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
1940 1950 1960 1970 1980 1990
710 720 730
mKIAA0 TGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::::::::::::
gi|819 TGDDLDPDIINILPASPTASPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQP
2000 2010 2020 2030 2040 2050
>>gi|149053743|gb|EDM05560.1| thyroid hormone receptor a (2040 aa)
initn: 4698 init1: 4698 opt: 4698 Z-score: 4716.1 bits: 884.7 E(): 0
Smith-Waterman score: 4698; 97.778% identity (99.028% similar) in 720 aa overlap (12-731:1179-1898)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|149 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1150 1160 1170 1180 1190 1200
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
1210 1220 1230 1240 1250 1260
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
1270 1280 1290 1300 1310 1320
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::.: ::
gi|149 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTLTPGV
1330 1340 1350 1360 1370 1380
230 240 250 260 270 280
mKIAA0 PISTSVATANSTLTTTSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQSG
::::::::::::::::::::::.:::::::::::::::::::::::::::::.::::::
gi|149 AISTSVATANSTLTTTSSSSSSSMSSGVSSNKLPSFPPFGSMNTSGTGSMSAQGSTVQSG
1390 1400 1410 1420 1430 1440
290 300 310 320 330 340
mKIAA0 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 QLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIVVY
1450 1460 1470 1480 1490 1500
350 360 370 380 390 400
mKIAA0 IIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVKHD
::::::::::::::.::::::::::::::::.::::::::::::::::::::::::::::
gi|149 IIDPFTYENKDESTSSSNVWTLGLLRCFLEMLQTLPPHIKSTVSVQIVPCQYLLQPVKHD
1510 1520 1530 1540 1550 1560
410 420 430 440 450 460
mKIAA0 DRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
gi|149 DRQIYSQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLYTP
1570 1580 1590 1600 1610 1620
470 480 490 500 510 520
mKIAA0 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 PFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCIINI
1630 1640 1650 1660 1670 1680
530 540 550 560 570 580
mKIAA0 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 DVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLLSR
1690 1700 1710 1720 1730 1740
590 600 610 620 630 640
mKIAA0 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 RNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRSTTL
1750 1760 1770 1780 1790 1800
650 660 670 680 690 700
mKIAA0 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 NMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDLLD
1810 1820 1830 1840 1850 1860
710 720 730
mKIAA0 TGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::.:::::::::::
gi|149 TGDDLDPDIINILPASPTTSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQQP
1870 1880 1890 1900 1910 1920
>>gi|73966750|ref|XP_537704.2| PREDICTED: similar to Thy (2182 aa)
initn: 3282 init1: 3251 opt: 4553 Z-score: 4570.0 bits: 857.8 E(): 0
Smith-Waterman score: 4553; 94.044% identity (98.476% similar) in 722 aa overlap (12-731:1319-2040)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|739 MLLFLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1290 1300 1310 1320 1330 1340
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
::::::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|739 DYDFLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1350 1360 1370 1380 1390 1400
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::.::.:::::::::.:.::::::::::::::::::::::::::::
gi|739 LGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1410 1420 1430 1440 1450 1460
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::::::::::::::::::: .:::.:.::::::::::.::::::::::::.:.::::
gi|739 GPYLASQPLDSSLLSQPNLVAPASQSLITSPQMTNTGNANTPSATLASAASSTITVTSGV
1470 1480 1490 1500 1510 1520
230 240 250 260 270
mKIAA0 PISTSVATANSTLTTTSSSSSSS--LSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
.:.:::::::::::::.::::: :.::::::::::::::::::.:.:::::.:..:::
gi|739 AMSSSVATANSTLTTTSTSSSSSSNLNSGVSSNKLPSFPPFGSMNSSATGSMSTQGNTVQ
1530 1540 1550 1560 1570 1580
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
.:::::::::.::.:::::::.:::.::::::::::::::::::::::::::::::::::
gi|739 NGQLGGQQSSALQTAGISGESSSLPAQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
1590 1600 1610 1620 1630 1640
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
1650 1660 1670 1680 1690 1700
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.:::::.:::::::::.::::::::::::::::::::::::::::::::::::::::::
gi|739 HEDRQIYTQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
1710 1720 1730 1740 1750 1760
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1770 1780 1790 1800 1810 1820
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
gi|739 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSSLL
1830 1840 1850 1860 1870 1880
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1890 1900 1910 1920 1930 1940
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|739 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1950 1960 1970 1980 1990 2000
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|739 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQGTDRLLSTESHDEVTNILQ
2010 2020 2030 2040 2050 2060
gi|739 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2070 2080 2090 2100 2110 2120
>>gi|4530437|gb|AAD22032.1| thyroid hormone receptor-ass (2174 aa)
initn: 3252 init1: 3221 opt: 4520 Z-score: 4536.9 bits: 851.7 E(): 0
Smith-Waterman score: 4520; 92.936% identity (98.061% similar) in 722 aa overlap (12-731:1311-2032)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|453 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1290 1300 1310 1320 1330 1340
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
:::.::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|453 DYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1350 1360 1370 1380 1390 1400
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::.:::::::::.::.:::::::::.:.::::::::::::::::::::::::::::
gi|453 LGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1410 1420 1430 1440 1450 1460
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::: ::::::::::::::: .:::.: ::::::::::.::::::::::::::.::::
gi|453 GPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSGV
1470 1480 1490 1500 1510 1520
230 240 250 260 270
mKIAA0 PISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
:::::::::::::: :::::::.:.::::::::::::::::::....::::.::.:::
gi|453 AISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQ
1530 1540 1550 1560 1570 1580
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.:::::::
gi|453 SGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAIV
1590 1600 1610 1620 1630 1640
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::: :::::::.:::::::::::::::::::::::::::::.::::::::::
gi|453 VYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVK
1650 1660 1670 1680 1690 1700
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.::.:: :::::::::.::::::::::::::::::::::::::::::.:::::::::::
gi|453 HEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRLY
1710 1720 1730 1740 1750 1760
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 APPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1770 1780 1790 1800 1810 1820
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|453 NIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
1830 1840 1850 1860 1870 1880
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1890 1900 1910 1920 1930 1940
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|453 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1950 1960 1970 1980 1990 2000
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|453 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQ
2010 2020 2030 2040 2050 2060
gi|453 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2070 2080 2090 2100 2110 2120
>>gi|119571823|gb|EAW51438.1| thyroid hormone receptor a (2174 aa)
initn: 3252 init1: 3221 opt: 4520 Z-score: 4536.9 bits: 851.7 E(): 0
Smith-Waterman score: 4520; 92.936% identity (98.061% similar) in 722 aa overlap (12-731:1311-2032)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|119 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1290 1300 1310 1320 1330 1340
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
:::.::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|119 DYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1350 1360 1370 1380 1390 1400
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::.:::::::::.::.:::::::::.:.::::::::::::::::::::::::::::
gi|119 LGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1410 1420 1430 1440 1450 1460
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::: ::::::::::::::: .:::.: ::::::::::.::::::::::::::.::::
gi|119 GPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSGV
1470 1480 1490 1500 1510 1520
230 240 250 260 270
mKIAA0 PISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
:::::::::::::: :::::::.:.::::::::::::::::::....::::.::.:::
gi|119 AISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQ
1530 1540 1550 1560 1570 1580
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.:::::::
gi|119 SGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAIV
1590 1600 1610 1620 1630 1640
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::: :::::::.:::::::::::::::::::::::::::::.::::::::::
gi|119 VYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVK
1650 1660 1670 1680 1690 1700
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.::.:: :::::::::.::::::::::::::::::::::::::::::.:::::::::::
gi|119 HEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRLY
1710 1720 1730 1740 1750 1760
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 APPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1770 1780 1790 1800 1810 1820
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|119 NIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
1830 1840 1850 1860 1870 1880
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1890 1900 1910 1920 1930 1940
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1950 1960 1970 1980 1990 2000
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|119 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQ
2010 2020 2030 2040 2050 2060
gi|119 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2070 2080 2090 2100 2110 2120
>>gi|166214951|sp|Q9UHV7.2|MED13_HUMAN RecName: Full=Med (2174 aa)
initn: 3252 init1: 3221 opt: 4520 Z-score: 4536.9 bits: 851.7 E(): 0
Smith-Waterman score: 4520; 92.936% identity (98.061% similar) in 722 aa overlap (12-731:1311-2032)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|166 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1290 1300 1310 1320 1330 1340
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
:::.::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|166 DYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1350 1360 1370 1380 1390 1400
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::.:::::::::.::.:::::::::.:.::::::::::::::::::::::::::::
gi|166 LGQHRPVSRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1410 1420 1430 1440 1450 1460
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::: ::::::::::::::: .:::.: ::::::::::.::::::::::::::.::::
gi|166 GPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTVTSGV
1470 1480 1490 1500 1510 1520
230 240 250 260 270
mKIAA0 PISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
:::::::::::::: :::::::.:.::::::::::::::::::....::::.::.:::
gi|166 AISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQ
1530 1540 1550 1560 1570 1580
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.:::::::
gi|166 SGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAIV
1590 1600 1610 1620 1630 1640
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::: :::::::.:::::::::::::::::::::::::::::.::::::::::
gi|166 VYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVK
1650 1660 1670 1680 1690 1700
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.::.:: :::::::::.::::::::::::::::::::::::::::::.:::::::::::
gi|166 HEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRLY
1710 1720 1730 1740 1750 1760
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 APPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1770 1780 1790 1800 1810 1820
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|166 NIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
1830 1840 1850 1860 1870 1880
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1890 1900 1910 1920 1930 1940
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1950 1960 1970 1980 1990 2000
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|166 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQ
2010 2020 2030 2040 2050 2060
gi|166 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2070 2080 2090 2100 2110 2120
>>gi|109114565|ref|XP_001110128.1| PREDICTED: mediator o (2174 aa)
initn: 3270 init1: 3237 opt: 4517 Z-score: 4533.9 bits: 851.1 E(): 0
Smith-Waterman score: 4517; 92.936% identity (98.061% similar) in 722 aa overlap (12-731:1311-2032)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|109 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1290 1300 1310 1320 1330 1340
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
:::.::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|109 DYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1350 1360 1370 1380 1390 1400
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::.:::::::::.::.:::.:::::.:.::::::::::::::::::::::::::::
gi|109 LGQHRPVSRLLTDGIMRVGSTASNKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1410 1420 1430 1440 1450 1460
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::: ::::::::::::::: .:::.: ::::::::::.:::::::::::::::::::
gi|109 GPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAASSTMTMTSGV
1470 1480 1490 1500 1510 1520
230 240 250 260 270
mKIAA0 PISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
:::::::::::::: :::::::.:.::::::::::::::::::....::::.::.:::
gi|109 AISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQ
1530 1540 1550 1560 1570 1580
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
::::::::.:.::.:::::::.::::::::::::::::::::::::::::::::::::::
gi|109 SGQLGGQQTSTLQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
1590 1600 1610 1620 1630 1640
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::: :::.:::.:::::::::::::::::::::::::::::.::::::::::
gi|109 VYIIDPFTYENTDESANSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVK
1650 1660 1670 1680 1690 1700
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.::.:: :::::::::.::::::::::::::::::::::::::::::.:::::::::::
gi|109 HEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRLY
1710 1720 1730 1740 1750 1760
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 APPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1770 1780 1790 1800 1810 1820
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|109 NIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
1830 1840 1850 1860 1870 1880
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1890 1900 1910 1920 1930 1940
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|109 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1950 1960 1970 1980 1990 2000
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|109 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDVGKGQSTDRLLSTEPHEEVPNILQ
2010 2020 2030 2040 2050 2060
gi|109 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2070 2080 2090 2100 2110 2120
>>gi|114669769|ref|XP_001138050.1| PREDICTED: mediator o (2188 aa)
initn: 3247 init1: 3221 opt: 4516 Z-score: 4532.8 bits: 850.9 E(): 0
Smith-Waterman score: 4516; 92.936% identity (98.061% similar) in 722 aa overlap (12-731:1325-2046)
10 20 30 40
mKIAA0 GTDESAVVPEIHQFHKSLGQPFYETDESPEPLPIPTFLLGY
.:::: :. : :::::::::::::::::
gi|114 MLLSLQPVLQDAIQKKRTVRPWGVQGPLTWQQFHKMAGRGSYGTDESPEPLPIPTFLLGY
1300 1310 1320 1330 1340 1350
50 60 70 80 90 100
mKIAA0 DYDFLVLSPFALPYWEKLMLEPYGSQRDIAYVVLCPENEALLNGARSFFRDLTAIYESCR
:::.::::::::::::.::::::::::::::::::::::::::::.::::::::::::::
gi|114 DYDYLVLSPFALPYWERLMLEPYGSQRDIAYVVLCPENEALLNGAKSFFRDLTAIYESCR
1360 1370 1380 1390 1400 1410
110 120 130 140 150 160
mKIAA0 LGQHRPISRLLTDGIMKVGATASKKLSEKFVTEWFSQAADGNNEAFSKLKLYAQVCRYDL
::::::::::::::::.::.:::::::::.:.::::::::::::::::::::::::::::
gi|114 LGQHRPISRLLTDGIMRVGSTASKKLSEKLVAEWFSQAADGNNEAFSKLKLYAQVCRYDL
1420 1430 1440 1450 1460 1470
170 180 190 200 210 220
mKIAA0 GPYLASQPLDSSLLSQPNLVAPPNQSLVTAPQMTNTGNANAPSATLASAASSTMTMTSGV
:::::: ::::::::::::::: .:::.: ::::::::::.::::::::.:::::.::::
gi|114 GPYLASLPLDSSLLSQPNLVAPTSQSLITPPQMTNTGNANTPSATLASAVSSTMTVTSGV
1480 1490 1500 1510 1520 1530
230 240 250 260 270
mKIAA0 PISTSVATANSTLTT--TSSSSSSSLSSGVSSNKLPSFPPFGSMNTSGTGSMSAQASTVQ
:::::::::::::: :::::::.:.::::::::::::::::::....::::.::.:::
gi|114 AISTSVATANSTLTTASTSSSSSSNLNSGVSSNKLPSFPPFGSMNSNAAGSMSTQANTVQ
1540 1550 1560 1570 1580 1590
280 290 300 310 320 330
mKIAA0 SGQLGGQQSSSLQAAGISGESASLPTQPHPDVSESTMDRDKVGIPTDGDSHAITYPPAIV
::::::::.:.::.:::::::.::::::::::::::::::::::::::::::.:::::::
gi|114 SGQLGGQQTSALQTAGISGESSSLPTQPHPDVSESTMDRDKVGIPTDGDSHAVTYPPAIV
1600 1610 1620 1630 1640 1650
340 350 360 370 380 390
mKIAA0 VYIIDPFTYENKDESTNSSNVWTLGLLRCFLEMVQTLPPHIKSTVSVQIVPCQYLLQPVK
::::::::::: :::::::.:::::::::::::::::::::::::::::.::::::::::
gi|114 VYIIDPFTYENTDESTNSSSVWTLGLLRCFLEMVQTLPPHIKSTVSVQIIPCQYLLQPVK
1660 1670 1680 1690 1700 1710
400 410 420 430 440 450
mKIAA0 HDDRQIYSQHLKSLAFSVFTQCRRPLPTSTNVKTLTGFGPGLAMETALKSPDRPECIRLY
:.::.:: :::::::::.::::::::::::::::::::::::::::::.:::::::::::
gi|114 HEDREIYPQHLKSLAFSAFTQCRRPLPTSTNVKTLTGFGPGLAMETALRSPDRPECIRLY
1720 1730 1740 1750 1760 1770
460 470 480 490 500 510
mKIAA0 TPPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 APPFILAPVKDKQTELGETFGEAGQKYNVLFVGYCLSHDQRWILASCTDLYGELLETCII
1780 1790 1800 1810 1820 1830
520 530 540 550 560 570
mKIAA0 NIDVPNRARRKKGSARRFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
::::::::::::.:::.:::::::::::::::::::::::::::::::::::::::::::
gi|114 NIDVPNRARRKKSSARKFGLQKLWEWCLGLVQMSSLPWRVVIGRLGRIGHGELKDWSCLL
1840 1850 1860 1870 1880 1890
580 590 600 610 620 630
mKIAA0 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 SRRNLQSLSKRLKDMCRMCGISAADSPSILSACLVAMEPQGSFVIMPDSVSTGSVFGRST
1900 1910 1920 1930 1940 1950
640 650 660 670 680 690
mKIAA0 TLNMQTPQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|114 TLNMQTSQLNTPQDTSCTHILVFPTSASVQVASATYTTENLDLAFNPNNDGADGMGIFDL
1960 1970 1980 1990 2000 2010
700 710 720 730
mKIAA0 LDTGDDLDPDIINILPASPTASPVHSPGSHYP
::::::::::::::::::::.:::::::::::
gi|114 LDTGDDLDPDIINILPASPTGSPVHSPGSHYPHGGDAGKGQSTDRLLSTEPHEEVPNILQ
2020 2030 2040 2050 2060 2070
gi|114 QPLALGYFVSTAKAGPLPDWFWSACPQAQYQCPLFLKASLHLHVPSVQSDELLHSKHSHP
2080 2090 2100 2110 2120 2130
731 residues in 1 query sequences
2727779818 residues in 7921681 library sequences
Tcomplib [34.26] (2 proc)
start: Sun Mar 15 09:17:54 2009 done: Sun Mar 15 09:25:59 2009
Total Scan time: 1068.660 Total Display time: 0.480
Function used was FASTA [version 34.26.5 April 26, 2007]