# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mbh00867.fasta.nr -Q ../query/mKIAA0696.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2 FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 mKIAA0696, 555 aa vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library 2727779818 residues in 7921681 sequences statistics sampled from 60000 to 7898492 sequences Expectation_n fit: rho(ln(x))= 5.6895+/-0.000195; mu= 9.6844+/- 0.011 mean_var=106.5645+/-20.400, 0's: 40 Z-trim: 130 B-trim: 0 in 0/68 Lambda= 0.124242 FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2 join: 37, opt: 25, open/ext: -10/-2, width: 16 The best scores are: opt bits E(7921681) gi|74213626|dbj|BAE35617.1| unnamed protein produc ( 508) 3450 629.2 8.5e-178 gi|7209809|dbj|BAA92329.1| F-box and WD-repeats pr ( 508) 3441 627.6 2.6e-177 gi|56207156|emb|CAI25520.1| F-box and WD-40 domain ( 542) 3361 613.3 5.6e-173 gi|21707854|gb|AAH34261.1| F-box and WD-40 domain ( 563) 3360 613.1 6.6e-173 gi|26334549|dbj|BAC30975.1| unnamed protein produc ( 529) 3358 612.8 8.1e-173 gi|74147468|dbj|BAE38644.1| unnamed protein produc ( 529) 3357 612.6 9.1e-173 gi|13124267|sp|Q9UKB1.1|FBW1B_HUMAN RecName: Full= ( 542) 3352 611.7 1.7e-172 gi|114603476|ref|XP_518097.2| PREDICTED: similar t ( 563) 3352 611.7 1.8e-172 gi|194219605|ref|XP_001499717.2| PREDICTED: F-box ( 529) 3349 611.2 2.5e-172 gi|73953432|ref|XP_866601.1| PREDICTED: similar to ( 531) 3349 611.2 2.5e-172 gi|73953434|ref|XP_852961.1| PREDICTED: similar to ( 563) 3349 611.2 2.6e-172 gi|194378960|dbj|BAG58031.1| unnamed protein produ ( 510) 3347 610.8 3.1e-172 gi|7209811|dbj|BAA92330.1| F-box and WD-repeats pr ( 529) 3347 610.8 3.2e-172 gi|149412478|ref|XP_001508141.1| PREDICTED: simila ( 638) 3338 609.3 1.1e-171 gi|126291455|ref|XP_001380485.1| PREDICTED: simila ( 610) 3334 608.5 1.8e-171 gi|53136810|emb|CAG32734.1| hypothetical protein [ ( 529) 3320 606.0 9.1e-171 gi|224068496|ref|XP_002187132.1| PREDICTED: F-box ( 513) 3279 598.6 1.4e-168 gi|14764438|gb|AAK72095.1| F-box/WD40 repeat-conta ( 563) 3240 591.6 2e-166 gi|223648174|gb|ACN10845.1| F-box/WD repeat-contai ( 526) 3133 572.4 1.1e-160 gi|223648038|gb|ACN10777.1| F-box/WD repeat-contai ( 525) 3129 571.7 1.8e-160 gi|34784880|gb|AAH56809.1| F-box and WD-40 domain ( 527) 3126 571.2 2.7e-160 gi|28277589|gb|AAH45356.1| F-box and WD-40 domain ( 527) 3104 567.2 4.1e-159 gi|89273756|emb|CAJ82085.1| beta-transducin repeat ( 534) 3044 556.5 7.1e-156 gi|133778111|gb|AAI23622.1| BTRC protein [Bos taur ( 569) 3034 554.7 2.6e-155 gi|118092941|ref|XP_421723.2| PREDICTED: similar t ( 589) 3030 554.0 4.3e-155 gi|73998278|ref|XP_543980.2| PREDICTED: similar to ( 506) 3029 553.8 4.4e-155 gi|224052707|ref|XP_002192900.1| PREDICTED: simila ( 680) 3030 554.1 4.8e-155 gi|194041873|ref|XP_001924863.1| PREDICTED: simila ( 722) 3030 554.1 5e-155 gi|51476320|emb|CAH18150.1| hypothetical protein [ ( 564) 3026 553.3 6.9e-155 gi|6164610|gb|AAF04464.1|AF129530_1 F-box protein ( 569) 3026 553.3 7e-155 gi|119570156|gb|EAW49771.1| beta-transducin repeat ( 579) 3026 553.3 7e-155 gi|67969559|dbj|BAE01128.1| unnamed protein produc ( 587) 3026 553.3 7.1e-155 gi|119570158|gb|EAW49773.1| beta-transducin repeat ( 506) 3025 553.1 7.3e-155 gi|13124271|sp|Q9Y297.1|FBW1A_HUMAN RecName: Full= ( 605) 3026 553.3 7.3e-155 gi|149412248|ref|XP_001511460.1| PREDICTED: simila ( 801) 3027 553.6 7.8e-155 gi|189066663|dbj|BAG36210.1| unnamed protein produ ( 569) 3025 553.1 7.9e-155 gi|126273483|ref|XP_001379239.1| PREDICTED: simila ( 587) 3025 553.1 8.1e-155 gi|114632433|ref|XP_507991.2| PREDICTED: beta-tran ( 670) 3025 553.2 8.8e-155 gi|54648390|gb|AAH85125.1| Beta-transducin repeat ( 506) 3023 552.7 9.3e-155 gi|119581844|gb|EAW61440.1| F-box and WD-40 domain ( 444) 3022 552.5 9.6e-155 gi|149040269|gb|EDL94307.1| beta-transducin repeat ( 569) 3023 552.7 1e-154 gi|161086889|ref|NP_001007149.2| beta-transducin r ( 619) 3023 552.8 1.1e-154 gi|194205747|ref|XP_001499916.2| PREDICTED: simila ( 587) 3018 551.9 1.9e-154 gi|4008020|gb|AAD08701.1| beta-TrCP protein E3RS-I ( 569) 3017 551.7 2.1e-154 gi|161086887|ref|NP_001032847.2| beta-transducin r ( 605) 3017 551.7 2.2e-154 gi|74216845|dbj|BAE26547.1| unnamed protein produc ( 605) 3017 551.7 2.2e-154 gi|148710006|gb|EDL41952.1| beta-transducin repeat ( 631) 3017 551.7 2.3e-154 gi|74140158|dbj|BAE33798.1| unnamed protein produc ( 553) 3012 550.8 3.9e-154 gi|4140718|gb|AAD04181.1| beta-transducin repeat c ( 569) 3008 550.1 6.5e-154 gi|55726548|emb|CAH90041.1| hypothetical protein [ ( 605) 3005 549.5 9.9e-154 >>gi|74213626|dbj|BAE35617.1| unnamed protein product [M (508 aa) initn: 3450 init1: 3450 opt: 3450 Z-score: 3348.3 bits: 629.2 E(): 8.5e-178 Smith-Waterman score: 3450; 100.000% identity (100.000% similar) in 508 aa overlap (48-555:1-508) 20 30 40 50 60 70 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELMISNGTSSVIVSRKRP :::::::::::::::::::::::::::::: gi|742 MEPDSVIEDKTIELMISNGTSSVIVSRKRP 10 20 30 80 90 100 110 120 130 mKIAA0 SEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 SEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALP 40 50 60 70 80 90 140 150 160 170 180 190 mKIAA0 EQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 EQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSER 100 110 120 130 140 150 200 210 220 230 240 250 mKIAA0 RGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 RGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVY 160 170 180 190 200 210 260 270 280 290 300 310 mKIAA0 CLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 CLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRV 220 230 240 250 260 270 320 330 340 350 360 370 mKIAA0 WDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 WDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 280 290 300 310 320 330 380 390 400 410 420 430 mKIAA0 AVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 AVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNT 340 350 360 370 380 390 440 450 460 470 480 490 mKIAA0 IRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 IRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 400 410 420 430 440 450 500 510 520 530 540 550 mKIAA0 LRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|742 LRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR 460 470 480 490 500 >>gi|7209809|dbj|BAA92329.1| F-box and WD-repeats protei (508 aa) initn: 3441 init1: 3441 opt: 3441 Z-score: 3339.6 bits: 627.6 E(): 2.6e-177 Smith-Waterman score: 3441; 99.606% identity (100.000% similar) in 508 aa overlap (48-555:1-508) 20 30 40 50 60 70 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELMISNGTSSVIVSRKRP :::::::::::::::::::::::::::::: gi|720 MEPDSVIEDKTIELMISNGTSSVIVSRKRP 10 20 30 80 90 100 110 120 130 mKIAA0 SEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 SEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQRDFITALP 40 50 60 70 80 90 140 150 160 170 180 190 mKIAA0 EQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 EQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDPLWKGLSER 100 110 120 130 140 150 200 210 220 230 240 250 mKIAA0 RGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 RGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCRSENSKGVY 160 170 180 190 200 210 260 270 280 290 300 310 mKIAA0 CLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRV ::::::.::::::::::::::::.:::::::::::::::::::::::::::::::::::: gi|720 CLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRV 220 230 240 250 260 270 320 330 340 350 360 370 mKIAA0 WDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 WDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 280 290 300 310 320 330 380 390 400 410 420 430 mKIAA0 AVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 AVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNT 340 350 360 370 380 390 440 450 460 470 480 490 mKIAA0 IRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 IRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 400 410 420 430 440 450 500 510 520 530 540 550 mKIAA0 LRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|720 LRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRTYTYISR 460 470 480 490 500 >>gi|56207156|emb|CAI25520.1| F-box and WD-40 domain pro (542 aa) initn: 3361 init1: 3361 opt: 3361 Z-score: 3261.8 bits: 613.3 E(): 5.6e-173 Smith-Waterman score: 3372; 93.727% identity (93.727% similar) in 542 aa overlap (48-555:1-542) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELM--------------- ::::::::::::::: gi|562 MEPDSVIEDKTIELMCSVPRSLWLGCANLV 10 20 30 70 80 90 100 mKIAA0 -------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVE ::::::::::::::::::::::::::::::::::::::::: gi|562 ESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVE 40 50 60 70 80 90 110 120 130 140 150 160 mKIAA0 FVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 FVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELV 100 110 120 130 140 150 170 180 190 200 210 220 mKIAA0 CKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 CKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYP 160 170 180 190 200 210 230 240 250 260 270 280 mKIAA0 KIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 KIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSL 220 230 240 250 260 270 290 300 310 320 330 340 mKIAA0 ECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 ECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSN 280 290 300 310 320 330 350 360 370 380 390 400 mKIAA0 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWST 340 350 360 370 380 390 410 420 430 440 450 460 mKIAA0 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 400 410 420 430 440 450 470 480 490 500 510 520 mKIAA0 FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|562 FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSH 460 470 480 490 500 510 530 540 550 mKIAA0 DDTILIWDFLNVPPSAQNETRSPSRTYTYISR :::::::::::::::::::::::::::::::: gi|562 DDTILIWDFLNVPPSAQNETRSPSRTYTYISR 520 530 540 >>gi|21707854|gb|AAH34261.1| F-box and WD-40 domain prot (563 aa) initn: 3439 init1: 3356 opt: 3360 Z-score: 3260.6 bits: 613.1 E(): 6.6e-173 Smith-Waterman score: 3360; 96.512% identity (97.481% similar) in 516 aa overlap (48-555:48-563) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIED--------KTIELMISNGTSS .. ::.:: :. .::::::: gi|217 VPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKSALWQISNGTSS 20 30 40 50 60 70 70 80 90 100 110 120 mKIAA0 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ 80 90 100 110 120 130 130 140 150 160 170 180 mKIAA0 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP 140 150 160 170 180 190 190 200 210 220 230 240 mKIAA0 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR 200 210 220 230 240 250 250 260 270 280 290 300 mKIAA0 SENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 SENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTG 260 270 280 290 300 310 310 320 330 340 350 360 mKIAA0 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR 320 330 340 350 360 370 370 380 390 400 410 420 mKIAA0 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV 380 390 400 410 420 430 430 440 450 460 470 480 mKIAA0 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP 440 450 460 470 480 490 490 500 510 520 530 540 mKIAA0 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|217 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT 500 510 520 530 540 550 550 mKIAA0 YTYISR :::::: gi|217 YTYISR 560 >>gi|26334549|dbj|BAC30975.1| unnamed protein product [M (529 aa) initn: 3436 init1: 3356 opt: 3358 Z-score: 3259.0 bits: 612.8 E(): 8.1e-173 Smith-Waterman score: 3398; 96.030% identity (96.030% similar) in 529 aa overlap (48-555:1-529) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELM--------------- ::::::::::::::: gi|263 MEPDSVIEDKTIELMNTSVMEDQNEDESPK 10 20 30 70 80 90 100 110 mKIAA0 ------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 KSALWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ 40 50 60 70 80 90 120 130 140 150 160 170 mKIAA0 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML 100 110 120 130 140 150 180 190 200 210 220 230 mKIAA0 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNW 160 170 180 190 200 210 240 250 260 270 280 290 mKIAA0 RCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 RCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSV 220 230 240 250 260 270 300 310 320 330 340 350 mKIAA0 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA 280 290 300 310 320 330 360 370 380 390 400 410 mKIAA0 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK 340 350 360 370 380 390 420 430 440 450 460 470 mKIAA0 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG 400 410 420 430 440 450 480 490 500 510 520 530 mKIAA0 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|263 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP 460 470 480 490 500 510 540 550 mKIAA0 PSAQNETRSPSRTYTYISR ::::::::::::::::::: gi|263 PSAQNETRSPSRTYTYISR 520 >>gi|74147468|dbj|BAE38644.1| unnamed protein product [M (529 aa) initn: 3435 init1: 3355 opt: 3357 Z-score: 3258.0 bits: 612.6 E(): 9.1e-173 Smith-Waterman score: 3397; 95.841% identity (96.030% similar) in 529 aa overlap (48-555:1-529) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELM--------------- ::::::::::::::: gi|741 MEPDSVIEDKTIELMNTSVMEDQNEDESPK 10 20 30 70 80 90 100 110 mKIAA0 ------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 KSALWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ 40 50 60 70 80 90 120 130 140 150 160 170 mKIAA0 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML 100 110 120 130 140 150 180 190 200 210 220 230 mKIAA0 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: gi|741 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETVESNW 160 170 180 190 200 210 240 250 260 270 280 290 mKIAA0 RCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 RCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSV 220 230 240 250 260 270 300 310 320 330 340 350 mKIAA0 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA 280 290 300 310 320 330 360 370 380 390 400 410 mKIAA0 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK 340 350 360 370 380 390 420 430 440 450 460 470 mKIAA0 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG 400 410 420 430 440 450 480 490 500 510 520 530 mKIAA0 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|741 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP 460 470 480 490 500 510 540 550 mKIAA0 PSAQNETRSPSRTYTYISR ::::::::::::::::::: gi|741 PSAQNETRSPSRTYTYISR 520 >>gi|13124267|sp|Q9UKB1.1|FBW1B_HUMAN RecName: Full=F-bo (542 aa) initn: 3352 init1: 3352 opt: 3352 Z-score: 3253.0 bits: 611.7 E(): 1.7e-172 Smith-Waterman score: 3363; 93.358% identity (93.727% similar) in 542 aa overlap (48-555:1-542) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELM--------------- ::::::::::::::: gi|131 MEPDSVIEDKTIELMCSVPRSLWLGCANLV 10 20 30 70 80 90 100 mKIAA0 -------------------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVE ::::::::::::::::::::::::::::::::::::::::: gi|131 ESMCALSCLQSMPSVRCLQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVE 40 50 60 70 80 90 110 120 130 140 150 160 mKIAA0 FVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 FVEHLISRMCHYQHGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELV 100 110 120 130 140 150 170 180 190 200 210 220 mKIAA0 CKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 CKEWQRVISEGMLWKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYP 160 170 180 190 200 210 230 240 250 260 270 280 mKIAA0 KIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSL ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::.:: gi|131 KIIQDIETIESNWRCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSL 220 230 240 250 260 270 290 300 310 320 330 340 mKIAA0 ECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 ECLKVLTGHTGSVLCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSN 280 290 300 310 320 330 350 360 370 380 390 400 mKIAA0 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 GLMVTCSKDRSIAVWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWST 340 350 360 370 380 390 410 420 430 440 450 460 mKIAA0 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 STCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR 400 410 420 430 440 450 470 480 490 500 510 520 mKIAA0 FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|131 FDNKRIVSGAYDGKIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSH 460 470 480 490 500 510 530 540 550 mKIAA0 DDTILIWDFLNVPPSAQNETRSPSRTYTYISR :::::::::::::::::::::::::::::::: gi|131 DDTILIWDFLNVPPSAQNETRSPSRTYTYISR 520 530 540 >>gi|114603476|ref|XP_518097.2| PREDICTED: similar to F- (563 aa) initn: 3433 init1: 3350 opt: 3352 Z-score: 3252.8 bits: 611.7 E(): 1.8e-172 Smith-Waterman score: 3352; 96.318% identity (97.481% similar) in 516 aa overlap (48-555:48-563) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIED--------KTIELMISNGTSS .. ::.:: :. .::::::: gi|114 VPRSLWLGCANLVESMCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKNTLWQISNGTSS 20 30 40 50 60 70 70 80 90 100 110 120 mKIAA0 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ 80 90 100 110 120 130 130 140 150 160 170 180 mKIAA0 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP 140 150 160 170 180 190 190 200 210 220 230 240 mKIAA0 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR 200 210 220 230 240 250 250 260 270 280 290 300 mKIAA0 SENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTG ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: gi|114 SENSKGVYCLQYDDEKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTG 260 270 280 290 300 310 310 320 330 340 350 360 mKIAA0 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR 320 330 340 350 360 370 370 380 390 400 410 420 mKIAA0 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV 380 390 400 410 420 430 430 440 450 460 470 480 mKIAA0 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP 440 450 460 470 480 490 490 500 510 520 530 540 mKIAA0 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|114 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT 500 510 520 530 540 550 550 mKIAA0 YTYISR :::::: gi|114 YTYISR 560 >>gi|194219605|ref|XP_001499717.2| PREDICTED: F-box and (529 aa) initn: 3427 init1: 3347 opt: 3349 Z-score: 3250.3 bits: 611.2 E(): 2.5e-172 Smith-Waterman score: 3389; 95.652% identity (96.030% similar) in 529 aa overlap (48-555:1-529) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIEDKTIELM--------------- ::::::::::::::: gi|194 MEPDSVIEDKTIELMNTSVMEDQNEDESPK 10 20 30 70 80 90 100 110 mKIAA0 ------ISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 KSTLWQISNGTSSVIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQ 40 50 60 70 80 90 120 130 140 150 160 170 mKIAA0 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 HGHINSYLKPMLQRDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGML 100 110 120 130 140 150 180 190 200 210 220 230 mKIAA0 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 WKKLIERMVRTDPLWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNW 160 170 180 190 200 210 240 250 260 270 280 290 mKIAA0 RCGRHNLQRIQCRSENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSV :::::::::::::::::::::::::::.::::::::::::::::.::::::::::::::: gi|194 RCGRHNLQRIQCRSENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV 220 230 240 250 260 270 300 310 320 330 340 350 mKIAA0 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 LCLQYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIA 280 290 300 310 320 330 360 370 380 390 400 410 mKIAA0 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 VWDMASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHK 340 350 360 370 380 390 420 430 440 450 460 470 mKIAA0 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 RGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDG 400 410 420 430 440 450 480 490 500 510 520 530 mKIAA0 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|194 KIKVWDLQAALDPRAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVP 460 470 480 490 500 510 540 550 mKIAA0 PSAQNETRSPSRTYTYISR ::::::::::::::::::: gi|194 PSAQNETRSPSRTYTYISR 520 >>gi|73953432|ref|XP_866601.1| PREDICTED: similar to F-b (531 aa) initn: 3347 init1: 3347 opt: 3349 Z-score: 3250.2 bits: 611.2 E(): 2.5e-172 Smith-Waterman score: 3349; 96.124% identity (97.481% similar) in 516 aa overlap (48-555:16-531) 20 30 40 50 60 mKIAA0 LPPPPPPPPPPPPGPIAAERRERGGAAGAAMEPDSVIED--------KTIELMISNGTSS .. ::.:: :. .::::::: gi|739 MCALSCLQSMPSVRCLQNTSVMEDQNEDESPKKNTLWQISNGTSS 10 20 30 40 70 80 90 100 110 120 mKIAA0 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 VIVSRKRPSEGNYQKEKDLCIKYFDQWSESDQVEFVEHLISRMCHYQHGHINSYLKPMLQ 50 60 70 80 90 100 130 140 150 160 170 180 mKIAA0 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 RDFITALPEQGLDHIAENILSYLDARSLCAAELVCKEWQRVISEGMLWKKLIERMVRTDP 110 120 130 140 150 160 190 200 210 220 230 240 mKIAA0 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 LWKGLSERRGWDQYLFKNRPTDGPPNSFYRSLYPKIIQDIETIESNWRCGRHNLQRIQCR 170 180 190 200 210 220 250 260 270 280 290 300 mKIAA0 SENSKGVYCLQYDDDKIISGLRDNSIKIWDKSSLECLKVLTGHTGSVLCLQYDERVIVTG ::::::::::::::.::::::::::::::::.:::::::::::::::::::::::::::: gi|739 SENSKGVYCLQYDDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQYDERVIVTG 230 240 250 260 270 280 310 320 330 340 350 360 mKIAA0 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 SSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRFSNGLMVTCSKDRSIAVWDMASATDITLR 290 300 310 320 330 340 370 380 390 400 410 420 mKIAA0 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 RVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRLV 350 360 370 380 390 400 430 440 450 460 470 480 mKIAA0 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 VSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLQAALDP 410 420 430 440 450 460 490 500 510 520 530 540 mKIAA0 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: gi|739 RAPASTLCLRTLVEHSGRVFRLQFDEFQIISSSHDDTILIWDFLNVPPSAQNETRSPSRT 470 480 490 500 510 520 550 mKIAA0 YTYISR :::::: gi|739 YTYISR 530 555 residues in 1 query sequences 2727779818 residues in 7921681 library sequences Tcomplib [34.26] (2 proc) start: Sun Mar 15 23:05:15 2009 done: Sun Mar 15 23:12:22 2009 Total Scan time: 955.820 Total Display time: 0.170 Function used was FASTA [version 34.26.5 April 26, 2007]