FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA1823.ptfa, 376 aa
vs ./tmplib.26680 library
1768641 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 6.1569+/-0.00491; mu= 7.2718+/- 0.327
mean_var=131.4925+/-30.509, 0's: 0 Z-trim: 8 B-trim: 0 in 0/36
Lambda= 0.1118
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 37, opt: 25, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA1333 ( 731 res) mpm08381 ( 731) 299 59 7.7e-10
mKIAA4050 ( 762 res) mbg07005 ( 762) 225 48 3.1e-06
mKIAA0304 ( 1744 res) mbg06324 (1744) 219 47 1.1e-05
mKIAA1506 ( 1520 res) mbg19167 (1520) 174 40 0.0015
mKIAA1820 ( 1518 res) mpm10033 (1518) 165 38 0.0041
>>mKIAA1333 ( 731 res) mpm08381 (731 aa)
initn: 270 init1: 247 opt: 299 Z-score: 269.0 bits: 59.4 E(): 7.7e-10
Smith-Waterman score: 299; 33.333% identity (34.677% ungapped) in 129 aa overlap (18-144:18-143)
10 20 30 40 50
mKIAA1 GLKWQSLNTLKIMSSSIEQKKGSTRQRKCGFCKSNRD--KECGQLLISENQKVAAHHKCM
:.: .... : ::..: : .. :. :. . ..:. :.
mKIAA1 RRARGQTEVSRAAGKMNENKPDNSQSLACVFCRKNDDCPNKYGEKKTYEKWNFSVHYYCL
10 20 30 40 50 60
60 70 80 90 100 110
mKIAA1 LFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYH
:.::.. . ...:.. :: :::..::..:..:: :..:. ::.::: : ::.:.::
mKIAA1 LMSSGIWQRGKEEEGVYGFLIEDIRKEVQRASKLKCTVCKKNGASIGCVVPTCKRSYHLP
70 80 90 100 110 120
120 130 140 150 160 170
mKIAA1 CALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKTKKKSRKGR
:.:. . .. . . .: ::.
mKIAA1 CGLQKECIFQFTDN---FASFCWKHRPVQAITSNKYSSSLPCTICLEFVEPIPTYNILQS
130 140 150 160 170
>>mKIAA4050 ( 762 res) mbg07005 (762 aa)
initn: 218 init1: 155 opt: 225 Z-score: 204.2 bits: 47.5 E(): 3.1e-06
Smith-Waterman score: 251; 24.747% identity (28.161% ungapped) in 198 aa overlap (148-341:396-573)
120 130 140 150 160 170
mKIAA1 HCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKTKKKSRKG
:: :. . : .: : ::
mKIAA4 SVKKSRFWEPNKVSNNSGMLPNAVLPPSLDHNYAQWQEREESSHTEQP--PLMKKIIPAP
370 380 390 400 410 420
180 190 200 210 220 230
mKIAA1 RPRKTNLKGLPEDSRSTSSHGTDEMESSSYRDRSPHRSSP---NDTRPKCGFC-HVGEEE
.:. : :.. . .. :. ::. . : .:.: .:..: :..
mKIAA4 KPKGP---GEPDSPTPLHPPTPPILSTDRSREDSPELNPPPGIDDNR-QCALCLMYGDDS
430 440 450 460 470
240 250 260 270 280 290
mKIAA1 NEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCT
. :.: .. ... .: .: :.:. . : : ..:.: . . :::...:
mKIAA4 ANDAGRL-LYIGQNEWTHVNCALWSAEVF--------EDDDGSLKNVHMAVIRGKQLRCE
480 490 500 510 520 530
300 310 320 330 340 350
mKIAA1 LCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEE
.:..::::.:: . .:...::. :. . .... :.::. :
mKIAA4 FCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDK-----KVYCQRHRDLIKGEVVPEN
540 550 560 570 580
360 370
mKIAA1 RESKSRGRVAIDQQLTQQQLNGN
mKIAA4 GFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGILNDLSDCEDKLFPIGY
590 600 610 620 630 640
>>mKIAA0304 ( 1744 res) mbg06324 (1744 aa)
initn: 260 init1: 155 opt: 219 Z-score: 194.6 bits: 46.9 E(): 1.1e-05
Smith-Waterman score: 239; 24.516% identity (27.143% ungapped) in 155 aa overlap (189-342:601-741)
160 170 180 190 200 210
mKIAA1 NEHELEPSSPKTKKKSRKGRPRKTNLKGLPEDSRSTSSHGTDEMESSSYRDRSPHRSSPN
..:.. : :.......: :
mKIAA0 WRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQESETPESGQPPADPSAAFQSKDPAAFSHL
580 590 600 610 620 630
220 230 240 250 260 270
mKIAA1 DTRPKCGFC-HVGEEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDI
: .:..: . :. ... :.: .. ... .: .: ..:. . : .: ..
mKIAA0 DDPRQCALCLKYGDADSKEAGRL-LYIGQNEWTHVNCAIWSAEVF--------EENDGSL
640 650 660 670 680
280 290 300 310 320 330
mKIAA1 KTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLY
:.: . ::..:.: :: .::::.:: ...:....:. :. .:.: . . :..
mKIAA0 KNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCA---RASYC--IFQDDKKVF
690 700 710 720 730
340 350 360 370
mKIAA1 CKNHSGNDERDEEDEERESKSRGRVAIDQQLTQQQLNGN
:..:.
mKIAA0 CQKHTDLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDVINVLIGSIRINSLG
740 750 760 770 780 790
>>mKIAA1506 ( 1520 res) mbg19167 (1520 aa)
initn: 283 init1: 132 opt: 174 Z-score: 156.1 bits: 39.6 E(): 0.0015
Smith-Waterman score: 182; 22.663% identity (26.846% ungapped) in 353 aa overlap (14-341:797-1119)
10 20 30
mKIAA1 GLKWQSLNTLKIMSSSIEQKKGSTRQRKCGFCK-----SNRDK
:: . .: : . : :: :. :
mKIAA1 NPPRLATSYRLKQPNVPFPPTSNGLSGYKDSSHGPAEGASLRPQWCCHCKVVILGSGVRK
770 780 790 800 810 820
40 50 60 70 80
mKIAA1 ECGQLLI-----SENQK------VAAHHKC-MLFSSALVSSHSDN-ESLGGF---SIEDV
: .: . :: : : ..: .:.::: ...::: ::: .. ...
mKIAA1 SCKDLTFVNKGSRENTKRMEKDIVFCSNNCFILYSSAAQAKNSDNKESLPSLPQSPMKEP
830 840 850 860 870 880
90 100 110 120 130 140
mKIAA1 QKEIKRGTKLMCSL-CHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCR
.: ... .. . .: :: . :. . :... ::.. : .
mKIAA1 SKAFHQYSNNISTLDVHCLPQFQEKVSPPASPPISFPPAF-EAAKVESKPDELKVTVKLK
890 900 910 920 930 940
150 160 170 180 190
mKIAA1 KHKKTAHNSEADLEESFNEHELEPSSPKTKKKSRKGRPRKTNLKG-LPEDS-RSTSSHGT
. .:. . :: : .:: : . .: ... .:. . .
mKIAA1 PRLRTVPVG------------LEDCRP-LNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEI
950 960 970 980 990
200 210 220 230 240 250
mKIAA1 DEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEENEARGKLHIFNAK-KAAAHYKCMLFS
::. .. .: :.: : :: ::: : .. . : ...: .: .: :.:
mKIAA1 DEFLKKLGTCLKPD-PVPKDCR-KCCFCHE-EGDGLTDGPARLLNLDLDLWVHLNCALWS
1000 1010 1020 1030 1040
260 270 280 290 300 310
mKIAA1 SGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCG
. . . . . . .: ..:: .:::..: . ::: ::. :.. ::. :.
mKIAA1 TEVYETQAGA--------LINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCA
1050 1060 1070 1080 1090 1100
320 330 340 350 360 370
mKIAA1 VQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRVAIDQQLTQQQLNGN
.. . .... . . : :.
mKIAA1 TKAQCMFFKDKT-----MLCPMHKPKGIHEQQLSYFAVFRRVYVQRDEVRQIASIVQRGE
1110 1120 1130 1140 1150
>>mKIAA1820 ( 1518 res) mpm10033 (1518 aa)
initn: 209 init1: 151 opt: 165 Z-score: 148.2 bits: 38.1 E(): 0.0041
Smith-Waterman score: 205; 25.954% identity (30.909% ungapped) in 262 aa overlap (92-341:1282-1513)
70 80 90 100 110
mKIAA1 SALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPG--ATIGCDVKTCHRTYHYHC
:.: ::. :. .: :. : : ::
mKIAA1 GSVLQQRPSLPLSSTMHLGPVVSKALSTSCLVCCLCQNPANFKDLG-DL--CGPYYPEHC
1260 1270 1280 1290 1300
120 130 140 150 160 170
mKIAA1 ALHDKAQIREKPS-QGIYMVYCRKHKKTAHNSEADLEESFNEHELEPSSPKTKKKSRKGR
. : ...:: .: ..: .. :: : . :.. . ::
mKIAA1 LPKKKPKLKEKARLEGTLEEASLPLERTLKG----LECSASTTAAAPTTATITTPTALGR
1310 1320 1330 1340 1350 1360
180 190 200 210 220 230
mKIAA1 PRKTNLKGLP--EDSRSTSSHGTDEMESSSY-----RDRSPHRSSPNDTRP-KCGFCHVG
. . . : . ::..: .. .: : : . . .. . .: .:.
mKIAA1 LSRPDGPADPAKQGPLRTSARGLSRRLQSCYCCDGQGDGGEEVAQADKSRKHECS----K
1370 1380 1390 1400 1410 1420
240 250 260 270 280
mKIAA1 EEENEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQE-IKRGKR
: .: : .... .: : ...:: : :.. . :: ::: .: .
mKIAA1 EAPTEPGG-----DTQEHWVHEACAVWTSG-VYLVAGKL--FG-------LQEAMKVAVD
1430 1440 1450 1460
290 300 310 320 330 340
mKIAA1 MKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDE
: :: : .:::::.: :.:..:::: :. . .::. . : : .:.
mKIAA1 MPCTSCHEPGATISCSYKGCIHTYHYPCANDTGCTFIEEN----FTLKCPKHKRLPL
1470 1480 1490 1500 1510
350 360 370
mKIAA1 EDEERESKSRGRVAIDQQLTQQQLNGN
376 residues in 1 query sequences
1768641 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:53:55 2006 done: Mon Mar 27 10:53:55 2006
Scan time: 0.590 Display time: 0.080
Function used was FASTA [version 3.4t11 Apr 17, 2002]