FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA1838.ptfa, 650 aa
 vs ./tmplib.26680 library

1768367 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 5.2343+/-0.00431; mu= 13.6472+/- 0.287
 mean_var=108.5597+/-25.951, 0's: 0 Z-trim: 2  B-trim: 0 in 0/36
 Lambda= 0.1231

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 38, opt: 26, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA0183  ( 1175 res)   mpm10384                  (1175)  385   80 1.6e-15


>>mKIAA0183  ( 1175 res)   mpm10384                       (1175 aa)
 initn: 470 init1: 226 opt: 385  Z-score: 370.9  bits: 79.8 E(): 1.6e-15
Smith-Waterman score: 590;  25.333% identity (29.734% ungapped) in 750 aa overlap (4-650:64-805)

                                          10        20        30   
mKIAA1                            DPIMGVRGLQGFVGSTCPHICTIVNIHELAERH
                                     :::.:.: .. . ::   . :....::.  
mKIAA0 PAGRATALPPPAPPPPAPPPPARARPAAAAMGVQGFQDYIEKHCPSAVVPVELQKLARGS
            40        50        60        70        80        90   

                 40        50          60        70        80      
mKIAA1 -----RNKYPGCTPTIVVDAMCCLRYWYTA--ESWVCGGQWREYYCALRNFVAAFTSAGI
            :.. :     ..:::  ::.  : .   .:: :::: ..   :  .. :  ...:
mKIAA0 LVGGGRQRPPQTPLRLLVDADNCLHRLYGGFYTDWVSGGQWNHMLGYLAALAKACFGGNI
           100       110       120       130       140       150   

         90       100       110       120       130       140      
mKIAA1 KLIFFFDGMVEPGKRDEWVKRRLKNNREISKIFHYIKSKRDQPGRNMFFIPSGLAIFTRF
       .:. ::.: .: ..  :::::. .. .  ..:  ....:   : .  :. :  .:   :.
mKIAA0 ELFVFFNGALEKARLHEWVKRQGNERQTAQQIVSHVQNKGTPPPKVWFLPPVCMAHCIRL
           160       170       180       190       200       210   

        150       160       170       180       190       200      
mKIAA1 ALKTLGQETFCSLQEADYEVASYGLQHNCLGILGEDTDYLIYDTCPYFSIGDLCL----E
       ::  .  ..  :...   :: ..  ...  :... :.:: . .   :::   : :    .
mKIAA0 ALIRFHVKVAQSIEDHHQEVIGFCRENGFHGLVAYDSDYALCNIPYYFSAHALKLSRNGK
           220       230       240       250       260       270   

            210       220       230       240       250            
mKIAA1 SLQTIMLCREKLCESLGLRVADLPLLACLLGNDITPESMFESFRYKCLSS---YASVKEN
       :: : .   ... ..: :    .:..: :::: : :.  . ::... :.     ::.:  
mKIAA0 SLTTSQYLMHEVAKQLDLNPNRFPIFAALLGNHILPDEDLASFHWSLLGPEHPLASLKVR
           280       290       300       310       320       330   

     260            270                  280       290       300   
mKIAA1 AGKK-----GNIILAVSDYISKVLH-----------LYQGEKKIEEMLPLGPNKALFYKG
       : .        .: ::.::. .. :           ..:  ..  .   .  ..:. : .
mKIAA0 AHQLVLPPCDVVIKAVADYVRNI-HDTSDLDAIAKDVFQHSQSRTDDKVIRFKRAVGYYS
           340       350        360       370       380       390  

           310       320              330          340        350  
mKIAA1 VTSYLLPGQKSPWLVQKPK-----GMITD--KQQMVSLNPES---KQEVPMCIDPE-FKQ
       .::  .: .  :  . .:.     ::.      ::...   :   :  ::.  .:     
mKIAA0 ATSKPMPFHP-PHYLARPNPFGMPGMVPPYVPPQMLNIPQTSLQAKPAVPQVPSPGGTPG
            400        410       420       430       440       450 

            360       370          380       390               400 
mKIAA1 EVPVCTNPESMQEVPMCMDPEPN---QEASMCTDPESKQEVPM--------CTDSESKPE
       ..:    : :..:  . .:   .   .. :. . :.  ...:.         ..: :  .
mKIAA0 QAPY---PYSLSEPALTLDTSGKNLTEQNSYSNIPHEGKHTPLYERSSPINLAQSGSPNH
                460       470       480       490       500        

             410                   420       430        440        
mKIAA1 VSQYTNPESKQKLPSGID------------TEFNLEALMCTHPE-FKQEDVMDMEPEIKQ
       :..   : :. .  :  :            .... :    .: : . . :  :.     .
mKIAA0 VDSAYFPGSSTSSSSDNDEGGGGATNHISGNKIGWEKTG-SHAEPLARGDPGDQVKVEGS
      510       520       530       540        550       560       

      450         460                 470        480            490
mKIAA1 VTMVSESEIL--KASD--------C--ASPTSVH-NVVIESVPQVA----RM-HHVHSES
        :  : :..   :.:         :  . ::  : ...   .: ::    :. .: :...
mKIAA0 STASSGSQLAEGKGSHMGTVQPIPCLLSMPTRNHMDITTPPLPPVAPEVLRVAEHRHKKG
       570       580       590       600       610       620       

                 500       510       520       530       540       
mKIAA1 YL---VYNILSSGEIECSNTLEDELDQALPSQAFIYRPVRQRVYALLLGDWKDGAST---
        .   ...::..:::. . ..::: .. ::  :..:::::: ::..:..  ..  .:   
mKIAA0 LMYPYIFHILTKGEIKIAVSIEDEANKDLPPAALLYRPVRQYVYGVLFSLAESRKKTERL
       630       640       650       660       670       680       

                      550       560       570       580       590  
mKIAA1 -----------GP-VVKEWFVYPGNSLKHPDLVRPLQMTVQGGTPSLEVLWLSQEPAVQA
                  .: ..::: .: :.: . :.::. : .  .   :.:. :::..    . 
mKIAA0 AFRKNRLPPEFSPLIIKEWAAYKGKSPQTPELVEALAFR-EWTCPNLKRLWLGKAVEDKN
       690       700       710       720        730       740      

            600       610         620       630       640       650
mKIAA1 QRLDTLLACFNLSSSREELQAVESP--LRALCCLLIYLFVQVHAELTVLYDIESPLSLAL
       .:. ..:::.  :..   :. .. :  : .:::.: :.     :..    .... :. ::
mKIAA0 RRMRAFLACMR-SDTPAMLNPANVPTHLMVLCCVLRYMVQWPGARILRRQELDAFLAQAL
        750        760       770       780       790       800     

mKIAA0 SPKLYEPDQLQELKIDNLDPRGIQLSALFMSGVDMALFANDACGQPIPWEHCCPWMYFDG
         810       820       830       840       850       860     




650 residues in 1 query   sequences
1768367 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 10:54:10 2006 done: Mon Mar 27 10:54:11 2006
 Scan time:  0.800 Display time:  0.060

Function used was FASTA [version 3.4t11 Apr 17, 2002]