FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0237.ptfa, 263 aa
vs ./tmplib.26680 library
1768754 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 4.5626+/-0.0043; mu= 13.6242+/- 0.289
mean_var=81.9591+/-19.188, 0's: 0 Z-trim: 9 B-trim: 135 in 1/35
Lambda= 0.1417
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 36, opt: 24, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA0751 ( 1297 res) mpg01166 (1297) 1255 266 5.3e-72
mFLJ00307 ( 516 res) mtg01156 ( 516) 184 47 2.3e-06
mKIAA4194 ( 320 res) mbg12940 ( 320) 154 41 0.00012
mKIAA1597 ( 407 res) mnh09216 ( 407) 145 39 0.00049
mKIAA0538 ( 826 res) msh37311 ( 826) 148 40 0.0005
mKIAA4186 ( 899 res) mfj00029 ( 899) 143 39 0.0011
>>mKIAA0751 ( 1297 res) mpg01166 (1297 aa)
initn: 1253 init1: 917 opt: 1255 Z-score: 1385.1 bits: 266.2 E(): 5.3e-72
Smith-Waterman score: 1255; 71.591% identity (71.863% ungapped) in 264 aa overlap (1-263:1032-1295)
10 20 30
mKIAA0 RRSSLGAKMVAIVGLTQWSKSTLQLPQPEG
::::.::::::::::.. :.:. :: : ::
mKIAA0 SISGDMCSLEKNDGSQSDTAVGALGTSGKKRRSSIGAKMVAIVGLSRKSRSASQLSQTEG
1010 1020 1030 1040 1050 1060
40 50 60 70 80
mKIAA0 ATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSEGTFIFP-TRLGAESQF
. :::::...::::::.:::::. .:::.:::::::: :: ::::..::: .::...:::
mKIAA0 GGKKLRSTVQRSTETGLAVEMRNWMTRQASRESTDGSMNSYSSEGNLIFPGVRLASDSQF
1070 1080 1090 1100 1110 1120
90 100 110 120 130 140
mKIAA0 SDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATY
:::::::::::.::::::::: :::.....::..::::::.:.::::. :::::.::: :
mKIAA0 SDFLDGLGPAQLVGRQTLATPAMGDIQVGMMDKKGQLEVEIIRARGLVVKPGSKTLPAPY
1130 1140 1150 1160 1170 1180
150 160 170 180 190 200
mKIAA0 IKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFDEGPQGKVLQVIVWGDYGRMDHKCFM
.:.:::.::.:.::::::::.:: .::::: : :.:.:::.:::.:::::::::::: ::
mKIAA0 VKVYLLDNGVCIAKKKTKVARKTLEPLYQQLLSFEESPQGRVLQIIVWGDYGRMDHKSFM
1190 1200 1210 1220 1230 1240
210 220 230 240 250 260
mKIAA0 GMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS
:.:::.::::.:: : ::.:::: ::..: ::. :::: :::::::.:.:: :
mKIAA0 GVAQILLDELELSNMVIGWFKLFPPSSLVDPTLAPLTRRASQSSLESSTGPSYSRS
1250 1260 1270 1280 1290
>>mFLJ00307 ( 516 res) mtg01156 (516 aa)
initn: 134 init1: 86 opt: 184 Z-score: 206.7 bits: 46.9 E(): 2.3e-06
Smith-Waterman score: 184; 23.045% identity (25.455% ungapped) in 243 aa overlap (1-231:214-445)
10 20 30
mKIAA0 RRSSLGAKMVAIVGLTQWSKSTLQLPQPEG
:: . :::.. . . :: .. : :
mFLJ00 CTVCFEDRNVKIKTGEWFFEERARKFPTAGRRETAGAKLLQ--SYQRLSKISVVPPTPPP
190 200 210 220 230 240
40 50 60 70 80
mKIAA0 -ATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSEGTFIFP--TRLGAES
. .. :...... : .... .. .: .: . .: : :.
mFLJ00 FSESQCSSSVQKASTPDILKAFHQEDPKHPPDPVLKQDTPPSSPTHSAVFSGGLRHGSLI
250 260 270 280 290 300
90 100 110 120 130 140
mKIAA0 QFSDFLDGLG---PAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKS
.... .: :...:. .: .: . .: .::. . ..:. .:
mFLJ00 SINSTCTEMGNFDNANVTGEIEFA------IHYCV--KSCSLEICIKTCKNLAYGEEKKR
310 320 330 340 350
150 160 170 180 190 200
mKIAA0 LPATYIKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFDEGP---QGKVLQVIVWGDYG
:.:.::: . . .:.::.: :.: :: ....: .. : . . ::: :: :
mFLJ00 KCNPYVKTYLLPDRSSQGKRKTRVQKNTLDPTFEETLKYQVDPGQLMTRRLQVSVW-HLG
360 370 380 390 400 410
210 220 230 240 250
mKIAA0 RMDHKCFMG---MAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESAT
. .. :.: . : : : .: . :: :
mFLJ00 TLARRVFLGEVILPLAMWDFKDSTAQNARWYPLRAKAEKYEENIPQNNGELAVRAKLVLP
420 430 440 450 460 470
260
mKIAA0 SPSCS
mFLJ00 AGPRKPQEAQEGQLALNGQLCLVVLGAKNLPVRSDGTLNSFVKG
480 490 500 510
>>mKIAA4194 ( 320 res) mbg12940 (320 aa)
initn: 107 init1: 107 opt: 154 Z-score: 176.0 bits: 40.5 E(): 0.00012
Smith-Waterman score: 161; 31.333% identity (36.719% ungapped) in 150 aa overlap (112-243:172-317)
90 100 110 120 130
mKIAA0 RLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAI--MDRSGQLEVEVIEARGLTPK
.::. .. . .:.: : ..::..: :
mKIAA4 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLK-K
150 160 170 180 190 200
140 150 160 170 180 190
mKIAA0 PGSKSLPATYIKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFDEGP--QGKVLQVIVW
.: :.: .:..:: . :::: : ::: .: ..... : : : : . .::.:
mKIAA4 MDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSF-EIPFEQIQKVQVVVT
210 220 230 240 250
200 210 220 230 240
mKIAA0 G-DYGRMDH-----KCFMGMAQIMLDEL----DLSA----AVTGWYKLFPTSSVADSTLG
:: .. . : :.: .. :: :. : .. :..: : : :. ::
mKIAA4 VLDYDKLGKNEAIGKIFVG-SNATGTELRHWSDMLANPRRPIAQWHSLKPEEEV-DALLG
260 270 280 290 300 310
250 260
mKIAA0 SLTRRLSQSSLESATSPSCS
.
mKIAA4 KNK
320
>>mKIAA1597 ( 407 res) mnh09216 (407 aa)
initn: 101 init1: 101 opt: 145 Z-score: 164.8 bits: 38.8 E(): 0.00049
Smith-Waterman score: 153; 24.324% identity (26.341% ungapped) in 222 aa overlap (44-261:48-256)
20 30 40 50 60 70
mKIAA0 GLTQWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSS
:: : : .. : ..: .. :: .::
mKIAA1 LPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRY--KKSPSSLTNLSSS
20 30 40 50 60 70
80 90 100 110 120 130
mKIAA0 EGTFIFPTRLGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEA
: . . : : .: . .: .. : .: . .. .:.: : .
mKIAA1 SGMTSLSSASG--SVMSVYSGDFGNLEVKGSVQFA--------LDYVESLKELHVFVAQC
80 90 100 110 120
140 150 160 170 180 190
mKIAA0 RGLTPKPGSKSLPATYIKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFDEGPQ---GK
. :. .:. :.:.::: . . ..:::: :.::: .:.:.. : . : .
mKIAA1 KDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQ
130 140 150 160 170 180
200 210 220 230 240
mKIAA0 VLQVIVWGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTS-SVADSTLGSLTRRL
:.. :: . .. :.: ... :. : .. . : .: . ..: .: . .:
mKIAA1 KLNLSVW-HRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYPLKRKTAPVALETENRGE
190 200 210 220 230 240
250 260
mKIAA0 SQSSLESATSPSCS
. .:. . ::
mKIAA1 MKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQK
250 260 270 280 290 300
>>mKIAA0538 ( 826 res) msh37311 (826 aa)
initn: 77 init1: 50 opt: 148 Z-score: 164.6 bits: 39.8 E(): 0.0005
Smith-Waterman score: 148; 26.619% identity (29.600% ungapped) in 139 aa overlap (113-245:142-272)
90 100 110 120 130
mKIAA0 LGAESQFSDFLDGLGPAQIVGRQTLATPPMGDVHIAIMDRSG----QLEVEVIEARGLTP
:..:. . : .:. :.::: :.:
mKIAA0 CLTRDALASHPKGFSGWTHLVEVDPNEEVQGEIHLRLEVVPGVHASRLRCAVLEARDLAP
120 130 140 150 160 170
140 150 160 170 180 190
mKIAA0 KP-GSKSLPATYIKAYLLENGACVAKKKTKVAKKTCDPLYQQALLFD-EGPQGKVLQVIV
: .. : : ..... :: ..:.:.::.: : ..... :. : ...: : .
mKIAA0 KDRNGASDP--FVRVHY--NGRT---QETSVVKKSCYPRWNETFDFELEKGASEALLVEA
180 190 200 210 220
200 210 220 230 240 250
mKIAA0 WGDYGRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLES
: :. .... :.: . . ...: . ::..: : .: . . :.:
mKIAA0 W-DWDLVSQNDFLGKVVVNVQRLCSAQQEEGWFRLQPDQSKSRQGKGNLGSLQLEVRLRD
230 240 250 260 270 280
260
mKIAA0 ATSPSCS
mKIAA0 ETVLPSVCYQPLVQLLCQEVKLGTQGPGRLIPVIEETTSAECRQEVATTLLKLFLGQGLA
290 300 310 320 330 340
>>mKIAA4186 ( 899 res) mfj00029 (899 aa)
initn: 144 init1: 72 opt: 143 Z-score: 158.6 bits: 38.8 E(): 0.0011
Smith-Waterman score: 143; 33.333% identity (35.922% ungapped) in 111 aa overlap (126-231:784-891)
100 110 120 130 140 150
mKIAA0 LGPAQIVGRQTLATPPMGDVHIAIMDRSGQLEVEVIEARGLTPKPGSKSLPATYIKAYLL
:.: : :.::: .: . : :.. :::
mKIAA4 VSLNTEAGDSRQGRLGEIQLTVRYVCLRHCLRVLVNGCRNLTPCTSSGADP--YVRIYLL
760 770 780 790 800 810
160 170 180 190 200 210
mKIAA0 ENGACVAKKKTKVAKKTCDPLYQQALLFDEGPQGKV----LQVIVWGDYGRMDHK-CFMG
. ...:::.: .:: .::..... : :.:.: :.: : .. .:. .:
mKIAA4 PERRWASRKKTSVKQKTLEPLFDETFEF-FVPMGEVQKRSLDVAVKNSRPLGSHRRKELG
820 830 840 850 860 870
220 230 240 250 260
mKIAA0 MAQIMLDELDLSAAVTGWYKLFPTSSVADSTLGSLTRRLSQSSLESATSPSCS
. : :.. :: . . ::.:
mKIAA4 KVLIDLSKQDLIKGFSQWYELTADGQPRS
880 890
263 residues in 1 query sequences
1768754 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:15:30 2006 done: Mon Mar 27 10:15:31 2006
Scan time: 0.490 Display time: 0.050
Function used was FASTA [version 3.4t11 Apr 17, 2002]