FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA0228.ptfa, 557 aa
 vs ./tmplib.26680 library

1768460 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 4.8207+/-0.00422; mu= 12.9159+/- 0.279
 mean_var=81.9580+/-18.854, 0's: 0 Z-trim: 3  B-trim: 153 in 1/35
 Lambda= 0.1417

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mKIAA2000  ( 1263 res)   mic17043                  (1263)  185   48 4.1e-06
mKIAA0664  ( 1237 res)   mbg01465                  (1237)  149   41 0.00067


>>mKIAA2000  ( 1263 res)   mic17043                       (1263 aa)
 initn: 266 init1: 142 opt: 185  Z-score: 202.1  bits: 48.4 E(): 4.1e-06
Smith-Waterman score: 222;  25.490% identity (26.749% ungapped) in 255 aa overlap (260-504:876-1128)

     230       240       250       260       270       280         
mKIAA0 VKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDI
                                     .:     : .: ..  . :.:.  : .:.:
mKIAA2 GKDKGAMATEYFESLKQYENSEGEENMLCLADLYETLGRFLKDLGLLSQAVVPLQRSLEI
         850       860       870       880       890       900     

     290       300       310       320           330        340    
mKIAA0 RQSVFGGKNIHVATAHEDLAYSSYVHQYSSGK----FDNALFHAERAIGII-THILPEDH
       :....   . .:: . ..:: . ::.  . :     . .::  .: : :    :   : .
mKIAA2 RETALDPDHPRVAQSLHQLA-GVYVQWKKFGDAEQLYKQALEISENAYGADHPHAARELE
         910       920        930       940       950       960    

              350       360       370        380       390         
mKIAA0 LLLA----SSKRVKALILEEIAIDCHNKETEQR-LLQEAHDLHLSSLQLAKKAFGEFNVQ
        : .    ..:  .:  ... ..  ... :...  :     :.  .::: . ..:. . .
mKIAA2 ALATLYHKQNKYEQAEHFRKKSVIIRQQATRRKGSLYGFALLRRRALQLEELTLGKDKPE
          970       980       990      1000      1010      1020    

     400       410       420       430       440       450         
mKIAA0 TAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQ
       .:.  ..:: ::  . ... ::..  ......:..:: .  . : :...::.: : . .:
mKIAA2 NARTLNELGVLYFLQNNLETAEQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCN-EKKQ
         1030      1040      1050      1060      1070       1080   

     460       470       480       490       500       510         
mKIAA0 YENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVLSNWNRLR
       ::.::.:: :.. : .. ..  . .: :  . :  ::.. :. .:.              
mKIAA2 YEKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKTGKVDKAVPLYELAVEIRQKS
          1090      1100      1110      1120      1130      1140   

     520       530       540       550                             
mKIAA0 DRQYSVTDALEDVSSSPQSTEEVVQSFLMAQNVEGPSC                      
                                                                   
mKIAA2 FGPKHPSVATALVNLAVLHSQMKKHSEALPLYERALKIYEDSLGRMHPRVGETLKNLAVL
          1150      1160      1170      1180      1190      1200   

>>mKIAA0664  ( 1237 res)   mbg01465                       (1237 aa)
 initn:  95 init1:  76 opt: 149  Z-score: 162.4  bits: 41.0 E(): 0.00067
Smith-Waterman score: 157;  27.919% identity (30.726% ungapped) in 197 aa overlap (179-363:936-1126)

      150       160       170       180         190            200 
mKIAA0 CKYHLGEETFKLAQTYMDKLSKHGQQANRAALYGELCAL--LFAKSHY-----DEAYKWC
                                     :.. :.::   :.:. ::      :: .  
mKIAA0 SGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLHYIMGDYAEALSNQ
         910       920       930       940       950       960     

               210       220       230       240       250         
mKIAA0 VEA--MKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKY
        .:  :.: . :.    ...   . .  : .. ... : .:. .: ::    ::  ::..
mKIAA0 QKAVLMSERVMGIEHPNTIQEYMHLALYCFASSQLSTALSLLYRARYLMLLVFGEDHPEM
         970       980       990      1000      1010      1020     

     260         270       280       290       300       310       
mKIAA0 SDTLLD--YGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQY
       .  :::   :. : .: .   :. . . :: .  .  : : ..:: .:. .:    :.. 
mKIAA0 A--LLDNNIGLVLHGVMEYDLSLRFLENALAVTTKYHGPKALKVALSHHLVAR---VYE-
          1030      1040      1050      1060      1070             

       320       330       340        350       360       370      
mKIAA0 SSGKFDNALFHAERAIGIITHILPEDHL-LLASSKRVKALILEEIAIDCHNKETEQRLLQ
       :...: .:: : ...  :    : :::     ::. .: :  . .:..            
mKIAA0 SKAEFRSALQHEKEGYTIYKTQLGEDHEKTKESSEYLKCLTQQAVALQRTMNEIYRNGSS
    1080      1090      1100      1110      1120      1130         

        380       390       400       410       420       430      
mKIAA0 EAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLG
                                                                   
mKIAA0 ANIPPLKFTAPSMTSVLEQLNVINGILFIPLSQKDLENLKAEVARRHQLQEANRNRDKAE
    1140      1150      1160      1170      1180      1190         




557 residues in 1 query   sequences
1768460 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 10:15:12 2006 done: Mon Mar 27 10:15:13 2006
 Scan time:  0.720 Display time:  0.060

Function used was FASTA [version 3.4t11 Apr 17, 2002]