# /usr/local/bin/fasta34_t -T 4 -b50 -d10 -E0.01 -H -O./tmp/mbg07142.fasta.nr -Q ../query/mKIAA2016.ptfa /cdna4/rodent/rouge_util/new.rouge/nfasta/nr 2
FASTA searches a protein or DNA sequence data bank version 34.26.5 April 26, 2007
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
mKIAA2016, 1731 aa
vs /cdna4/rodent/rouge_util/new.rouge/nfasta/nr library
2727779818 residues in 7921681 sequences
statistics sampled from 60000 to 7916281 sequences
Expectation_n fit: rho(ln(x))= 5.5749+/-0.000189; mu= 14.0341+/- 0.011
mean_var=88.6972+/-16.904, 0's: 49 Z-trim: 77 B-trim: 5 in 1/64
Lambda= 0.136182
FASTA (3.5 Sept 2006) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 41, opt: 29, open/ext: -10/-2, width: 16
The best scores are: opt bits E(7921681)
gi|148669696|gb|EDL01643.1| T-cell lymphoma invasi (1715) 11310 2233.5 0
gi|166987611|sp|Q6ZPF3.2|TIAM2_MOUSE RecName: Full (1715) 11300 2231.5 0
gi|5264503|dbj|BAA81823.1| sif and Tiam1-like exch (1715) 11291 2229.8 0
gi|44890483|gb|AAH67048.1| Tiam2 protein [Mus musc (1714) 11283 2228.2 0
gi|119568077|gb|EAW47692.1| T-cell lymphoma invasi (1725) 9570 1891.6 0
gi|6224676|gb|AAF05900.1|AF120323_1 T-cell lymphom (1077) 6033 1196.6 0
gi|149038494|gb|EDL92824.1| rCG41163 [Rattus norve ( 903) 5528 1097.3 0
gi|221044294|dbj|BAH13824.1| unnamed protein produ (1045) 5312 1054.9 0
gi|74196483|dbj|BAE34377.1| unnamed protein produc ( 788) 5207 1034.2 0
gi|57997048|emb|CAB59259.2| hypothetical protein [ (1013) 5102 1013.6 0
gi|166987615|sp|Q8IVF5.3|TIAM2_HUMAN RecName: Full (1701) 5102 1013.8 0
gi|62088928|dbj|BAD92911.1| T-cell lymphoma invasi (1947) 5102 1013.8 0
gi|55663246|emb|CAH73978.1| T-cell lymphoma invasi (1046) 5091 1011.5 0
gi|114609903|ref|XP_527545.2| PREDICTED: T-cell ly (1701) 5091 1011.6 0
gi|73946164|ref|XP_541162.2| PREDICTED: similar to (1487) 5029 999.4 0
gi|118088397|ref|XP_419687.2| PREDICTED: similar t (1705) 4445 884.7 0
gi|224048039|ref|XP_002198583.1| PREDICTED: T-cell (1706) 4405 876.9 0
gi|74183620|dbj|BAE36649.1| unnamed protein produc ( 619) 4032 803.2 0
gi|6224678|gb|AAF05901.1|AF120324_1 T-cell lymphom ( 626) 3563 711.1 7.5e-202
gi|221042866|dbj|BAH13110.1| unnamed protein produ ( 626) 3557 709.9 1.7e-201
gi|44890457|gb|AAH66979.1| T-cell lymphoma invasio ( 626) 3520 702.6 2.6e-199
gi|193784820|dbj|BAG53973.1| unnamed protein produ (1367) 3353 670.1 3.6e-189
gi|34531561|dbj|BAC86170.1| unnamed protein produc (1268) 3032 607.0 3.3e-170
gi|210106376|gb|EEA54365.1| hypothetical protein B (1948) 2627 527.6 4e-146
gi|90081126|dbj|BAE90043.1| unnamed protein produc ( 438) 2567 515.3 4.6e-143
gi|189540022|ref|XP_700972.3| PREDICTED: similar t ( 730) 2192 441.8 1e-120
gi|47219522|emb|CAG09876.1| unnamed protein produc (2108) 2088 421.7 3.2e-114
gi|189540235|ref|XP_001922135.1| PREDICTED: simila ( 729) 1845 373.6 3.4e-100
gi|189531323|ref|XP_001920795.1| PREDICTED: simila ( 931) 1820 368.8 1.2e-98
gi|152031709|sp|Q13009.2|TIAM1_HUMAN RecName: Full (1591) 1722 349.7 1.2e-92
gi|118083796|ref|XP_416699.2| PREDICTED: similar t (1594) 1722 349.7 1.2e-92
gi|149742171|ref|XP_001498883.1| PREDICTED: T-cell (1591) 1721 349.5 1.3e-92
gi|6841024|gb|AAF28865.1| T-cell lymphoma invasion ( 267) 1709 346.5 1.8e-92
gi|897557|gb|AAA98443.1| TIAM1 protein (1591) 1715 348.3 3e-92
gi|114683858|ref|XP_001162796.1| PREDICTED: T-cell (1591) 1714 348.1 3.4e-92
gi|74184517|dbj|BAE27881.1| unnamed protein produc (1496) 1709 347.1 6.5e-92
gi|148665967|gb|EDK98383.1| T-cell lymphoma invasi (1591) 1709 347.2 6.8e-92
gi|2494864|sp|Q60610.1|TIAM1_MOUSE RecName: Full=T (1591) 1707 346.8 8.9e-92
gi|74001093|ref|XP_544855.2| PREDICTED: similar to (1591) 1705 346.4 1.2e-91
gi|109065527|ref|XP_001098107.1| PREDICTED: T-cell (1591) 1702 345.8 1.8e-91
gi|74205264|dbj|BAE23147.1| unnamed protein produc ( 622) 1690 343.1 4.4e-91
gi|219518087|gb|AAI43981.1| Unknown (protein for M (1531) 1694 344.2 5.1e-91
gi|74188006|dbj|BAE37126.1| unnamed protein produc ( 743) 1685 342.2 1e-90
gi|194040881|ref|XP_001927581.1| PREDICTED: T-cell ( 623) 1676 340.4 3e-90
gi|149059797|gb|EDM10680.1| T-cell lymphoma invasi (1590) 1677 340.9 5.3e-90
gi|109492913|ref|XP_221672.4| PREDICTED: similar t (1860) 1673 340.1 1e-89
gi|62087782|dbj|BAD92338.1| T-cell lymphoma invasi (1060) 1640 333.5 6e-88
gi|224044143|ref|XP_002188532.1| PREDICTED: T-cell (1591) 1602 326.1 1.5e-85
gi|189524299|ref|XP_001924044.1| PREDICTED: T-cell (1684) 1597 325.2 3e-85
gi|13096547|pdb|1FOE|A Chain A, Crystal Structure ( 377) 1501 305.8 4.6e-80
>>gi|148669696|gb|EDL01643.1| T-cell lymphoma invasion a (1715 aa)
initn: 11310 init1: 11310 opt: 11310 Z-score: 12000.0 bits: 2233.5 E(): 0
Smith-Waterman score: 11310; 99.883% identity (100.000% similar) in 1715 aa overlap (17-1731:1-1715)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::::::::::::::::::::::::::::::::::::::::::
gi|148 MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
50 60 70 80 90 100
130 140 150 160 170 180
mKIAA2 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
110 120 130 140 150 160
190 200 210 220 230 240
mKIAA2 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
170 180 190 200 210 220
250 260 270 280 290 300
mKIAA2 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPSDTK
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|148 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTK
230 240 250 260 270 280
310 320 330 340 350 360
mKIAA2 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
290 300 310 320 330 340
370 380 390 400 410 420
mKIAA2 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
350 360 370 380 390 400
430 440 450 460 470 480
mKIAA2 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
410 420 430 440 450 460
490 500 510 520 530 540
mKIAA2 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
470 480 490 500 510 520
550 560 570 580 590 600
mKIAA2 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
530 540 550 560 570 580
610 620 630 640 650 660
mKIAA2 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
590 600 610 620 630 640
670 680 690 700 710 720
mKIAA2 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
650 660 670 680 690 700
730 740 750 760 770 780
mKIAA2 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
710 720 730 740 750 760
790 800 810 820 830 840
mKIAA2 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
770 780 790 800 810 820
850 860 870 880 890 900
mKIAA2 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVE
830 840 850 860 870 880
910 920 930 940 950 960
mKIAA2 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
890 900 910 920 930 940
970 980 990 1000 1010 1020
mKIAA2 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
mKIAA2 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
mKIAA2 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
mKIAA2 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
mKIAA2 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
mKIAA2 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
mKIAA2 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
mKIAA2 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
mKIAA2 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
mKIAA2 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
mKIAA2 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
mKIAA2 PTKDIELQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 PTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730
mKIAA2 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|148 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
1670 1680 1690 1700 1710
>>gi|166987611|sp|Q6ZPF3.2|TIAM2_MOUSE RecName: Full=T-l (1715 aa)
initn: 11300 init1: 11300 opt: 11300 Z-score: 11989.4 bits: 2231.5 E(): 0
Smith-Waterman score: 11300; 99.767% identity (100.000% similar) in 1715 aa overlap (17-1731:1-1715)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::::::::::::::::::::::::::::::::::::::::::
gi|166 MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
gi|166 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQ
50 60 70 80 90 100
130 140 150 160 170 180
mKIAA2 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
110 120 130 140 150 160
190 200 210 220 230 240
mKIAA2 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
170 180 190 200 210 220
250 260 270 280 290 300
mKIAA2 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPSDTK
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|166 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTK
230 240 250 260 270 280
310 320 330 340 350 360
mKIAA2 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
290 300 310 320 330 340
370 380 390 400 410 420
mKIAA2 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
350 360 370 380 390 400
430 440 450 460 470 480
mKIAA2 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
410 420 430 440 450 460
490 500 510 520 530 540
mKIAA2 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
470 480 490 500 510 520
550 560 570 580 590 600
mKIAA2 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
530 540 550 560 570 580
610 620 630 640 650 660
mKIAA2 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
590 600 610 620 630 640
670 680 690 700 710 720
mKIAA2 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
650 660 670 680 690 700
730 740 750 760 770 780
mKIAA2 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
710 720 730 740 750 760
790 800 810 820 830 840
mKIAA2 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
770 780 790 800 810 820
850 860 870 880 890 900
mKIAA2 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVE
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
gi|166 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALVCKMRQLEPTHYGLQLRKVVDKSVE
830 840 850 860 870 880
910 920 930 940 950 960
mKIAA2 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
890 900 910 920 930 940
970 980 990 1000 1010 1020
mKIAA2 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
mKIAA2 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
mKIAA2 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
mKIAA2 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
mKIAA2 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
mKIAA2 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
mKIAA2 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
mKIAA2 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
mKIAA2 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
mKIAA2 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
mKIAA2 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
mKIAA2 PTKDIELQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 PTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730
mKIAA2 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|166 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
1670 1680 1690 1700 1710
>>gi|5264503|dbj|BAA81823.1| sif and Tiam1-like exchange (1715 aa)
initn: 11291 init1: 11291 opt: 11291 Z-score: 11979.9 bits: 2229.8 E(): 0
Smith-Waterman score: 11291; 99.650% identity (99.942% similar) in 1715 aa overlap (17-1731:1-1715)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::::::::::::::::::::::::::::::::::::::::::
gi|526 MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
gi|526 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQ
50 60 70 80 90 100
130 140 150 160 170 180
mKIAA2 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
110 120 130 140 150 160
190 200 210 220 230 240
mKIAA2 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
170 180 190 200 210 220
250 260 270 280 290 300
mKIAA2 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPSDTK
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|526 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTK
230 240 250 260 270 280
310 320 330 340 350 360
mKIAA2 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
290 300 310 320 330 340
370 380 390 400 410 420
mKIAA2 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
350 360 370 380 390 400
430 440 450 460 470 480
mKIAA2 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
410 420 430 440 450 460
490 500 510 520 530 540
mKIAA2 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
470 480 490 500 510 520
550 560 570 580 590 600
mKIAA2 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
530 540 550 560 570 580
610 620 630 640 650 660
mKIAA2 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
590 600 610 620 630 640
670 680 690 700 710 720
mKIAA2 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
650 660 670 680 690 700
730 740 750 760 770 780
mKIAA2 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
710 720 730 740 750 760
790 800 810 820 830 840
mKIAA2 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
gi|526 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQQSTNSNKAHDLHLYGSAVDSAL
770 780 790 800 810 820
850 860 870 880 890 900
mKIAA2 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
gi|526 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDILALACKMRQLEPTHYGLQLRKVVDKSVE
830 840 850 860 870 880
910 920 930 940 950 960
mKIAA2 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
890 900 910 920 930 940
970 980 990 1000 1010 1020
mKIAA2 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
mKIAA2 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
mKIAA2 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
gi|526 QVPHREKMEQTFPSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
mKIAA2 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
mKIAA2 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
mKIAA2 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
mKIAA2 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
mKIAA2 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
mKIAA2 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
mKIAA2 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
mKIAA2 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
mKIAA2 PTKDIELQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 PTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730
mKIAA2 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|526 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
1670 1680 1690 1700 1710
>>gi|44890483|gb|AAH67048.1| Tiam2 protein [Mus musculus (1714 aa)
initn: 7162 init1: 7162 opt: 11283 Z-score: 11971.4 bits: 2228.2 E(): 0
Smith-Waterman score: 11283; 99.708% identity (99.942% similar) in 1715 aa overlap (17-1731:1-1714)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::::::::::::::::::::::::::::::::::::::::::
gi|448 MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
gi|448 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQ
50 60 70 80 90 100
130 140 150 160 170 180
mKIAA2 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
110 120 130 140 150 160
190 200 210 220 230 240
mKIAA2 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
170 180 190 200 210 220
250 260 270 280 290 300
mKIAA2 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPSDTK
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|448 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTK
230 240 250 260 270 280
310 320 330 340 350 360
mKIAA2 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
290 300 310 320 330 340
370 380 390 400 410 420
mKIAA2 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
350 360 370 380 390 400
430 440 450 460 470 480
mKIAA2 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
410 420 430 440 450 460
490 500 510 520 530 540
mKIAA2 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
470 480 490 500 510 520
550 560 570 580 590 600
mKIAA2 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
530 540 550 560 570 580
610 620 630 640 650 660
mKIAA2 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
gi|448 VFCLSNSCGDVYLFQATSQTDLENWVTAIHS-CASLFAKKHGKEDTVRLLKSQTRSLLQK
590 600 610 620 630 640
670 680 690 700 710 720
mKIAA2 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
650 660 670 680 690 700
730 740 750 760 770 780
mKIAA2 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
710 720 730 740 750 760
790 800 810 820 830 840
mKIAA2 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
770 780 790 800 810 820
850 860 870 880 890 900
mKIAA2 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVE
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
gi|448 RDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALVCKMRQLEPTHYGLQLRKVVDKSVE
830 840 850 860 870 880
910 920 930 940 950 960
mKIAA2 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 WCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISD
890 900 910 920 930 940
970 980 990 1000 1010 1020
mKIAA2 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 VLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCA
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
mKIAA2 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 SWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
mKIAA2 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 QVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKV
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
mKIAA2 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 IQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
mKIAA2 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 AISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKA
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
mKIAA2 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 FKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAM
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
mKIAA2 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 EKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
mKIAA2 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 ARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVR
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
mKIAA2 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 LGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIK
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
mKIAA2 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 CELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSL
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
mKIAA2 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 SSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGS
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
mKIAA2 PTKDIELQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 PTKDIEIQFQRLKISEESDVHPVGQQPLTESGEQPKLVRGHFCPIKRKANSTKRGRGTLL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730
mKIAA2 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|448 KAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
1670 1680 1690 1700 1710
>>gi|119568077|gb|EAW47692.1| T-cell lymphoma invasion a (1725 aa)
initn: 6356 init1: 5232 opt: 9570 Z-score: 10152.5 bits: 1891.6 E(): 0
Smith-Waterman score: 9570; 84.241% identity (94.148% similar) in 1726 aa overlap (17-1731:1-1725)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::.::::.:::::::::.::::: :::::::..:::.:::::
gi|119 MGNSDSQYTLQGSKNHSNTITGAKQIPCSLKIRGIHAKEEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
:: :::.::::::::::::::::::..::::.::.:::::::.:..:: ::.::::.:::
gi|119 GWGHGSNGAGYKSRSLARSCLSHFKSNQPYASRLGGPTCKVSRGVAYSTHRTNAPGKDFQ
50 60 70 80 90 100
130 140 150 160 170
mKIAA2 GNSGAFLPENGFHYVDRESEESHITS---NGHLLTCYGRKESLASTPPGEDHRSPRVLIK
: :.:: ::::: : .: ..:::: :::::.::::.::.::::::::..:::::::
gi|119 GISAAFSTENGFHSVGHELADNHITSRDCNGHLLNCYGRNESIASTPPGEDRKSPRVLIK
110 120 130 140 150 160
180 190 200 210 220 230
mKIAA2 TLGKLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPS
::::::::::::::::::: : .:: : ::.:::::::::::: :: :.:: :.: :
gi|119 TLGKLDGCLRVEFHNGGNPSKVPAEDCSEPVQLLRYSPTLASETSPVPEARRGSSADSLP
170 180 190 200 210 220
240 250 260 270 280 290
mKIAA2 SQRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPS
:.:::::::::::::::::::::::::::::::::.::..::::::. ::::: .::::.
gi|119 SHRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGELSEAEGSFLAPGMPDPSLHASFPPG
230 240 250 260 270 280
300 310 320 330 340 350
mKIAA2 DTKKPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPS
:.::::::::::::::::::: ::: :::: :: .::.....::.::::::::.::::
gi|119 DAKKPFNQSSSLSSLRELYKDANLGSLSPSGIRLS-DEYMGTHASLSNRVSFASDIDVPS
290 300 310 320 330 340
360 370 380 390 400 410
mKIAA2 RVDHRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSM
:: : ::..:::::::::: ::..::.::::.:::::::.:::::::::::::::::::
gi|119 RVAHGDPIQYSSFTLPCRKPKAFVEDTAKKDSLKARMRRISDWTGSLSRKKRKLQEPRSK
350 360 370 380 390 400
420 430 440 450 460 470
mKIAA2 EGSEYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFM
:::.::::.:::::.. : .:.:..::::::.: : .::::::::. ::::::::::::
gi|119 EGSDYFDSRSDGLNTDVQGSSQASAFLWSGGSTQILSQRSESTHAIGSDPLRQNIYENFM
410 420 430 440 450 460
480 490 500 510 520 530
mKIAA2 RELEMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQK
:::::::.:::..:::::: ::::::.::::::::::::::::::::::::::::::.::
gi|119 RELEMSRTNTENIETSTETAESSSESLSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTVQK
470 480 490 500 510 520
540 550 560 570 580 590
mKIAA2 ERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPK
:::::::::::::::::::::::::::::::::: .:.::::::::::::::::::::::
gi|119 ERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSMDQSSAPRCALFAEDSIVQSVPEHPK
530 540 550 560 570 580
600 610 620 630 640 650
mKIAA2 KEHVFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSL
::.::::::: ::::::::::::::::::::.:::::::::::::::::.::::.::..:
gi|119 KENVFCLSNSFGDVYLFQATSQTDLENWVTAVHSACASLFAKKHGKEDTLRLLKNQTKNL
590 600 610 620 630 640
660 670 680 690 700 710
mKIAA2 LQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQG
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
gi|119 LQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIQQWEQNLEKFHMDLFRMRCYLASLQG
650 660 670 680 690 700
720 730 740 750 760 770
mKIAA2 GELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKG
::::::::::::.::::::::::::.::::::::::::::::.::::::::::::..:::
gi|119 GELPNPKSLLAAASRPSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRNKKG
710 720 730 740 750 760
780 790 800 810 820 830
mKIAA2 IFSSLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDL-HLYGSAV
:::::::::::::::.::: ::::.:::: :::: ::::::.:.::... .: :.:::.:
gi|119 IFSSLKGLDTLARKGKEKRPSITQIFDSSGSHGFSGTQLPQNSSNSSEVDELLHIYGSTV
770 780 790 800 810 820
840 850 860 870 880 890
mKIAA2 DSALRDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVD
:.. ::. ::.:::::::::.:::: :::::::::.:.::::::::::.::::::::.::
gi|119 DGVPRDNAWEIQTYVHFQDNHGVTVGIKPEHRVEDILTLACKMRQLEPSHYGLQLRKLVD
830 840 850 860 870 880
900 910 920 930 940 950
mKIAA2 KSVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRI
.::.:.:: :::::.:::::::::::.::::::::::.. :::::::.::::.:::.::
gi|119 DNVEYCIPAPYEYMQQQVYDEIEVFPLNVYDVQLTKTGSVCDFGFAVTAQVDERQHLSRI
890 900 910 920 930 940
960 970 980 990 1000 1010
mKIAA2 FISDVLPDSLAYGGGLRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRR
::::::::.:::: :::::::: .:::: :::::..:::::::::::::::.::: :.
gi|119 FISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKA
950 960 970 980 990 1000
1020 1030 1040 1050 1060 1070
mKIAA2 TLCASWSDSDLFSRDQKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTE
:::.::::::::::::::: : ::::::::::::::.:....::::::.::::::::::.
gi|119 TLCTSWSDSDLFSRDQKSLLPPPNQSQLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTD
1010 1020 1030 1040 1050 1060
1080 1090 1100 1110 1120 1130
mKIAA2 GTLDQVPHREKMEQTFLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADR
:::::: ::::::::: ::.::. :::..:....:.::.: :..::::::::::::::::
gi|119 GTLDQVSHREKMEQTFRSAEQITALCRSFNDSQANGMEGPRENQDPPPRPLARHLSDADR
1070 1080 1090 1100 1110 1120
1140 1150 1160 1170 1180 1190
mKIAA2 LRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|119 LRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLE
1130 1140 1150 1160 1170 1180
1200 1210 1220 1230 1240 1250
mKIAA2 TLEDAISASSDFSVLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAK
::::.:::::::..:::::::::::::::::::::::::::::::::::::::.::::::
gi|119 TLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAK
1190 1200 1210 1220 1230 1240
1260 1270 1280 1290 1300 1310
mKIAA2 TDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEA
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
gi|119 TDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEA
1250 1260 1270 1280 1290 1300
1320 1330 1340 1350 1360 1370
mKIAA2 LKAMEKVASHINEMQKIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFL
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
gi|119 LKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFL
1310 1320 1330 1340 1350 1360
1380 1390 1400 1410 1420 1430
mKIAA2 SLGKARKDIELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISA
::::::::.:::::::::::::::::::::::::::::::::::.:::::::::::::::
gi|119 SLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISA
1370 1380 1390 1400 1410 1420
1440 1450 1460 1470 1480 1490
mKIAA2 LQVRLGNTAGTENNSTWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFR
::::::: ::::::: ::::::::::::::::::::::::::.::.::::::::::::::
gi|119 LQVRLGNPAGTENNSIWELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFR
1430 1440 1450 1460 1470 1480
1500 1510 1520 1530 1540 1550
mKIAA2 RHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSD
::::::::::::::::::::::::::::::::::::: :..:::.:: .: .::. ::::
gi|119 RHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSD
1490 1500 1510 1520 1530 1540
1560 1570 1580 1590 1600 1610
mKIAA2 ECSLSSGTQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPL
: ::::::::::::.::.:.::::: : . :::.: :.::::::::::::.: .. .
gi|119 EGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTV
1550 1560 1570 1580 1590 1600
1620 1630 1640 1650 1660
mKIAA2 KQGSPTKDIELQFQRLKISEESDVHPVG-QQPLTESGE------QPKLVRGHFCPIKRKA
::::::::::.:::::.:::. :::: . ::: :::: ::::::::::::::::
gi|119 KQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKA
1610 1620 1630 1640 1650 1660
1670 1680 1690 1700 1710 1720
mKIAA2 NSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHG
::::: :::::::: :::::::. :.:.:::: :::::::::::::::.:: ::::.:::
gi|119 NSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECFYETESHG
1670 1680 1690 1700 1710 1720
1730
mKIAA2 KS
::
gi|119 KS
>>gi|6224676|gb|AAF05900.1|AF120323_1 T-cell lymphoma in (1077 aa)
initn: 5083 init1: 4649 opt: 6033 Z-score: 6399.6 bits: 1196.6 E(): 0
Smith-Waterman score: 6033; 85.887% identity (94.708% similar) in 1077 aa overlap (663-1731:1-1077)
640 650 660 670 680 690
mKIAA2 CASLFAKKHGKEDTVRLLKSQTRSLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIR
:::::::::::::::::::::::::::::.
gi|622 MDSKMKKMAELQLSVVSDPKNRKAIENQIQ
10 20 30
700 710 720 730 740 750
mKIAA2 QWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSRPSKLALGRLGVLSVSSFHAL
:::::::::::::::::::::::::::::::::::::.::::: ::::::.:::::::::
gi|622 QWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAAASRPSKPALGRLGILSVSSFHAL
40 50 60 70 80 90
760 770 780 790 800 810
mKIAA2 VCSRDDSTLRKRTLSLTQRGKSKKGIFSSLKGLDTLARKGREKRASITQMFDSSHSHGFL
:::::::.::::::::::::..::::::::::::::::::.::: ::::.:::: ::::
gi|622 VCSRDDSALRKRTLSLTQRGRNKKGIFSSLKGLDTLARKGKEKRPSITQIFDSSGSHGFS
100 110 120 130 140 150
820 830 840 850 860 870
mKIAA2 GTQLPQKSTNSNKAHDL-HLYGSAVDSALRDSMWEVQTYVHFQDNEGVTVTIKPEHRVED
::::::.:.::... .: :.:::.::.. ::. ::.:::::::::.:::: :::::::::
gi|622 GTQLPQNSSNSSEVDELLHIYGSTVDGVPRDNTWEIQTYVHFQDNHGVTVGIKPEHRVED
160 170 180 190 200 210
880 890 900 910 920 930
mKIAA2 VLALACKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLT
.:.::::::::::.::::::::.:: .::.:.:: :::::.:::::::::::.:::::::
gi|622 ILTLACKMRQLEPSHYGLQLRKLVDDNVEYCIPAPYEYMQQQVYDEIEVFPLNVYDVQLT
220 230 240 250 260 270
940 950 960 970 980 990
mKIAA2 KTGDMTDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYGGGLRKGNEITSLNGEPVSDLDI
:::.. :::::::.::::.:::.::::::::::.:::: :::::::: .:::: :::::.
gi|622 KTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDL
280 290 300 310 320 330
1000 1010 1020 1030 1040 1050
mKIAA2 QQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRDQKSLPPSPNQSQLLEEFLDN
.:::::::::::::::.::: :. :::.::::::::::::::: : :::::::::::::
gi|622 KQMEALFSEKSVGLTLIARPPDTKATLCTSWSDSDLFSRDQKSLLPPPNQSQLLEEFLDN
340 350 360 370 380 390
1060 1070 1080 1090 1100 1110
mKIAA2 FRKTATSDFSNVPEITTGLKRSQTEGTLDQVPHREKMEQTFLSADQIAELCRDLNNTHTN
:.:....::::::.::::::::::.:::::: ::::::::: ::.::. :::..:....:
gi|622 FKKNTANDFSNVPDITTGLKRSQTDGTLDQVSHREKMEQTFRSAEQITALCRSFNDSQAN
400 410 420 430 440 450
1120 1130 1140 1150 1160 1170
mKIAA2 SMEAPTESHDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETF
.::.: :..:::::::::::::::::::::::::::::::::::::::::::::::::::
gi|622 GMEGPRENQDPPPRPLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETF
460 470 480 490 500 510
1180 1190 1200 1210 1220 1230
mKIAA2 LTQDEMESLFGSLPEMLEFQKVFLETLEDAISASSDFSVLETPSQFRKLLFSLGGSFLYY
:::::::::::::::::::::::::::::.:::::::..:::::::::::::::::::::
gi|622 LTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYY
520 530 540 550 560 570
1240 1250 1260 1270 1280 1290
mKIAA2 ADHFKLYSGFCANHIKVQRVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLK
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
gi|622 ADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLK
580 590 600 610 620 630
1300 1310 1320 1330 1340 1350
mKIAA2 YPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQKIYEDYGMVFDQLVAEQSGT
:::::::::::::.::::::::::::::::::::::::::::::::: ::::::::::::
gi|622 YPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGT
640 650 660 670 680 690
1360 1370 1380 1390 1400 1410
mKIAA2 EKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVFKRAVILVYKENCKLKKKLP
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
gi|622 EKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLP
700 710 720 730 740 750
1420 1430 1440 1450 1460 1470
mKIAA2 SNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNSTWELIHTKSEIEGRPETIFQ
:::::::::.:::::::::::::::::::::: ::::::: :::::::::::::::::::
gi|622 SNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTKSEIEGRPETIFQ
760 770 780 790 800 810
1480 1490 1500 1510 1520 1530
mKIAA2 LCCSDSENKTSIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRS
:::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::::
gi|622 LCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRS
820 830 840 850 860 870
1540 1550 1560 1570 1580 1590
mKIAA2 LKGLRTSSSSEWPSEPSKGNSLDSDECSLSSGTQSSGCPVAESRRDSKSTELEKDAQEGL
:: :..:::.:: .: .::. ::::: ::::::::::::.::.:.::::: : . ::
gi|622 LKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGL
880 890 900 910 920 930
1600 1610 1620 1630 1640 1650
mKIAA2 AEFPDGLIKESDILSDEDEDFHHPLKQGSPTKDIELQFQRLKISEESDVHPVG-QQPLTE
:.: :.::::::::::::.: .. .::::::::::.:::::.:::. :::: . ::: :
gi|622 ADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGPE
940 950 960 970 980 990
1660 1670 1680 1690 1700
mKIAA2 SGE------QPKLVRGHFCPIKRKANSTKRGRGTLLKAQTRHQSLDSHPETASIDLNLVL
::: ::::::::::::::::::::: :::::::: :::::::. :.:.:::: ::
gi|622 SGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVL
1000 1010 1020 1030 1040 1050
1710 1720 1730
mKIAA2 EREFSVQSLTSVVNEEGFYETQSHGKS
:::::::::::::.:: ::::.:::::
gi|622 EREFSVQSLTSVVSEECFYETESHGKS
1060 1070
>>gi|149038494|gb|EDL92824.1| rCG41163 [Rattus norvegicu (903 aa)
initn: 4714 init1: 4714 opt: 5528 Z-score: 5864.5 bits: 1097.3 E(): 0
Smith-Waterman score: 5528; 91.778% identity (97.556% similar) in 900 aa overlap (17-913:1-900)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
:::::::::::::::.::::::::::::::::::.:::::::::
gi|149 MGNSESQYTFQGSKNQSNTVTGAKQKPCSLKIRSIHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
::.:::.::::::::::::::::::.::::::::.::::::::::.::::::::::::::
gi|149 GWAHGSGGAGYKSRSLARSCLSHFKSHQPYATRLNGPTCKVSKGTAYSKHRANAPGNDFQ
50 60 70 80 90 100
130 140 150 160 170
mKIAA2 GNSGAFLPENGFHYVDRESEESHITS---NGHLLTCYGRKESLASTPPGEDHRSPRVLIK
::.:::::::::::: ::: :::::: ::::::::::..:.::::::::.::::::::
gi|149 GNNGAFLPENGFHYVGRESGESHITSRDCNGHLLTCYGRHDSIASTPPGEDRRSPRVLIK
110 120 130 140 150 160
180 190 200 210 220 230
mKIAA2 TLGKLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPS
:::::::::::::::::::::: ::::: ::.:::::::::.::::: :.:: :.::: .
gi|149 TLGKLDGCLRVEFHNGGNPHKGPSEDPSEPVQLLRYSPTLAAETCPVPESRRLSGAGSSA
170 180 190 200 210 220
240 250 260 270 280 290
mKIAA2 SQRPSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPS
::::::::: :::::::::::::::::::::::::.:::::.:::::. :::::::::::
gi|149 SQRPSPTDSCLRSSKGSSLSSESSWYDSPWGNAGEASEVDGTFLAPSALDPSLPSSFPPS
230 240 250 260 270 280
300 310 320 330 340 350
mKIAA2 DTKKPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPS
::::::::::::::::::::: ::::::::::::::::::::::.:::::::::::::::
gi|149 DTKKPFNQSSSLSSLRELYKDANLGCRSPSGTCLSSNEYISSQVGLNNRVSFASDMDVPS
290 300 310 320 330 340
360 370 380 390 400 410
mKIAA2 RVDHRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSM
:::::: ..::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 RVDHRDTMQYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRST
350 360 370 380 390 400
420 430 440 450 460 470
mKIAA2 EGSEYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFM
:::::::::::::::. : :.:::.:::::::::::::::::::::. :::.::::::::
gi|149 EGSEYFDSHSDGLNADVQGPTQTSALLWSGGSAQTLPHRSESTHAIGSDPLQQNIYENFM
410 420 430 440 450 460
480 490 500 510 520 530
mKIAA2 RELEMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQK
:::::::.: :..::::::.::::::.:::::::::::::::::::::::::::::::::
gi|149 RELEMSRTNMENAETSTETVESSSESLSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQK
470 480 490 500 510 520
540 550 560 570 580 590
mKIAA2 ERKLELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPK
::::::::::::::::::::::::.::::::::::.::::::::::::::::::::::::
gi|149 ERKLELVARRKWKQYWVTLKGCTLMFYETYGKNSTDQNSAPRCALFAEDSIVQSVPEHPK
530 540 550 560 570 580
600 610 620 630 640 650
mKIAA2 KEHVFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSL
:::::::::: :::::::::::::::::.:::::::::::::::::::::::::::::.:
gi|149 KEHVFCLSNSYGDVYLFQATSQTDLENWITAIHSACASLFAKKHGKEDTVRLLKSQTRGL
590 600 610 620 630 640
660 670 680 690 700 710
mKIAA2 LQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|149 LQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQG
650 660 670 680 690 700
720 730 740 750 760 770
mKIAA2 GELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKG
::::::::::::::::::::::::::::::::::::::::::.:::::::.:::.:::::
gi|149 GELPNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSALRKRTLSFTQRAKSKKG
710 720 730 740 750 760
780 790 800 810 820 830
mKIAA2 IFSSLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVD
.::::::::::::::::::::::::::::::::.:::::::.::::...::::::::..:
gi|149 LFSSLKGLDTLARKGREKRASITQMFDSSHSHGYLGTQLPQNSTNSSEVHDLHLYGSSAD
770 780 790 800 810 820
840 850 860 870 880 890
mKIAA2 SALRDSMWEVQTYVHFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDK
:.:::: ::::::::::::::::: ::::::::::::::::::.::::.::::::::::.
gi|149 STLRDSTWEVQTYVHFQDNEGVTVIIKPEHRVEDVLALACKMRHLEPTRYGLQLRKVVDE
830 840 850 860 870 880
900 910 920 930 940 950
mKIAA2 SVEWCVPALYEYMQEQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIF
::::::::::::::::
gi|149 SVEWCVPALYEYMQEQASL
890 900
>>gi|221044294|dbj|BAH13824.1| unnamed protein product [ (1045 aa)
initn: 4552 init1: 4118 opt: 5312 Z-score: 5634.3 bits: 1054.9 E(): 0
Smith-Waterman score: 5746; 84.689% identity (93.876% similar) in 1045 aa overlap (703-1731:1-1045)
680 690 700 710 720 730
mKIAA2 LQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSR
:::::::::::::::::::::::::::.::
gi|221 MDLFRMRCYLASLQGGELPNPKSLLAAASR
10 20 30
740 750 760 770 780 790
mKIAA2 PSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFSSLKGLDTLARKG
::::::::::.::::::::::::::::.::::::::::::..::::::::::::::::::
gi|221 PSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRNKKGIFSSLKGLDTLARKG
40 50 60 70 80 90
800 810 820 830 840 850
mKIAA2 REKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDL-HLYGSAVDSALRDSMWEVQTYV
.::: ::::.:::: :::: ::::::.:.::... .: :.:::.:... ::. ::.::::
gi|221 KEKRPSITQIFDSSGSHGFSGTQLPQNSSNSSEVDELLHIYGSTVNGVPRDNAWEIQTYV
100 110 120 130 140 150
860 870 880 890 900 910
mKIAA2 HFQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQ
:::::.:::: :::::::::.:.::::::::::.::::::::.:: .::.:.:: .::::
gi|221 HFQDNHGVTVGIKPEHRVEDILTLACKMRQLEPSHYGLQLRKLVDDNVEYCIPAPHEYMQ
160 170 180 190 200 210
920 930 940 950 960 970
mKIAA2 EQVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYGGG
.:::::::::::.::::::::::.. :::::::.::::.:::.::::::::::.:::: :
gi|221 QQVYDEIEVFPLNVYDVQLTKTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEG
220 230 240 250 260 270
980 990 1000 1010 1020 1030
mKIAA2 LRKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRD
::::::: .:::: :::::..:::::::::::::::.::: :. :::.:::::::::::
gi|221 LRKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKATLCTSWSDSDLFSRD
280 290 300 310 320 330
1040 1050 1060 1070 1080 1090
mKIAA2 QKSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLDQVPHREKMEQT
:::: : ::::::::::::::.:....::::::.::::::::::.:::::: ::::::::
gi|221 QKSLLPPPNQSQLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTDGTLDQVSHREKMEQT
340 350 360 370 380 390
1100 1110 1120 1130 1140 1150
mKIAA2 FLSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKVIQELVDTEKSY
: ::.::. :::..:....:.::.: :..:::::::::::::::::::::::::::::::
gi|221 FRSAEQITALCRSFNDSQANGMEGPRENQDPPPRPLARHLSDADRLRKVIQELVDTEKSY
400 410 420 430 440 450
1160 1170 1180 1190 1200 1210
mKIAA2 VKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDAISASSDFSVL
:::::::::::::::::::::::::::::::::::::::::::::::::.:::::::..:
gi|221 VKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTL
460 470 480 490 500 510
1220 1230 1240 1250 1260 1270
mKIAA2 ETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKAFKAFLDARNPT
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
gi|221 ETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPT
520 530 540 550 560 570
1280 1290 1300 1310 1320 1330
mKIAA2 KQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQ
:::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::
gi|221 KQHSSTLESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQ
580 590 600 610 620 630
1340 1350 1360 1370 1380 1390
mKIAA2 KIYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFV
::::::: :::::::::::::::::::::::::::::::::::::::::::::.::::::
gi|221 KIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFV
640 650 660 670 680 690
1400 1410 1420 1430 1440 1450
mKIAA2 FKRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNS
:::::::::::::::::::::::::::::.:::::::::::::::::::::: :::::::
gi|221 FKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNS
700 710 720 730 740 750
1460 1470 1480 1490 1500 1510
mKIAA2 TWELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIKCELPLEKTCKD
::::::::::::::::::::::::::.::.:::::::::::::::::::::::::::::
gi|221 IWELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKD
760 770 780 790 800 810
1520 1530 1540 1550 1560
mKIAA2 RLVPLKNRVPVSAKLA--------SSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSLSSG
:::::::::::::::: :::::: :..:::.:: .: .::. ::::: :::::
gi|221 RLVPLKNRVPVSAKLAKCVFLTVASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSG
820 830 840 850 860 870
1570 1580 1590 1600 1610 1620
mKIAA2 TQSSGCPVAESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGSPTK
:::::::.::.:.::::: : . :::.: :.::::::::::::.: .. .:::::::
gi|221 TQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTK
880 890 900 910 920 930
1630 1640 1650 1660 1670
mKIAA2 DIELQFQRLKISEESDVHPVG-QQPLTESGE------QPKLVRGHFCPIKRKANSTKRGR
:::.:::::.:::. :::: . ::: :::: ::::::::::::::::::::: :
gi|221 DIEVQFQRLRISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDR
940 950 960 970 980 990
1680 1690 1700 1710 1720 1730
mKIAA2 GTLLKAQTRHQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
::::::: :::::::. :.:.:::: :::::::::::::::.:: ::::.:::::
gi|221 GTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECFYETESHGKS
1000 1010 1020 1030 1040
>>gi|74196483|dbj|BAE34377.1| unnamed protein product [M (788 aa)
initn: 5248 init1: 5207 opt: 5207 Z-score: 5524.4 bits: 1034.2 E(): 0
Smith-Waterman score: 5207; 99.491% identity (99.873% similar) in 786 aa overlap (17-802:1-786)
10 20 30 40 50 60
mKIAA2 FRPWLILIQLFSILVKMGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
::::::::::::::::::::::::::::::::::::::::::::
gi|741 MGNSESQYTFQGSKNHSNTVTGAKQKPCSLKIRSVHAKDEKSLH
10 20 30 40
70 80 90 100 110 120
mKIAA2 GWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANAPGNDFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
gi|741 DWTHGSSGAGYKSRSLARSCLSHFKNHQPYATRLSGPTCKVSKGTTYSKHRANTPGNDFQ
50 60 70 80 90 100
130 140 150 160 170 180
mKIAA2 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 GNSGAFLPENGFHYVDRESEESHITSNGHLLTCYGRKESLASTPPGEDHRSPRVLIKTLG
110 120 130 140 150 160
190 200 210 220 230 240
mKIAA2 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 KLDGCLRVEFHNGGNPHKGTSEDPSGPVRLLRYSPTLASETCPVRETRRHSAAGSPSSQR
170 180 190 200 210 220
250 260 270 280 290 300
mKIAA2 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVDGSFLAPSTPDPSLPSSFPPSDTK
::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
gi|741 PSPTDSRLRSSKGSSLSSESSWYDSPWGNAGEVSEVEGSFLAPSTPDPSLPSSFPPSDTK
230 240 250 260 270 280
310 320 330 340 350 360
mKIAA2 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 KPFNQSSSLSSLRELYKDPNLGCRSPSGTCLSSNEYISSQVSLNNRVSFASDMDVPSRVD
290 300 310 320 330 340
370 380 390 400 410 420
mKIAA2 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 HRDPLHYSSFTLPCRKSKALTEDAAKKDTLKARMRRFSDWTGSLSRKKRKLQEPRSMEGS
350 360 370 380 390 400
430 440 450 460 470 480
mKIAA2 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 EYFDSHSDGLNAEGQVPAQTSSLLWSGGSAQTLPHRSESTHAISVDPLRQNIYENFMREL
410 420 430 440 450 460
490 500 510 520 530 540
mKIAA2 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 EMSRSNTEHVETSTETMESSSESVSSLEQLDLLFEKEQGVVRKAGWLFFKPLVTLQKERK
470 480 490 500 510 520
550 560 570 580 590 600
mKIAA2 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 LELVARRKWKQYWVTLKGCTLLFYETYGKNSTEQNSAPRCALFAEDSIVQSVPEHPKKEH
530 540 550 560 570 580
610 620 630 640 650 660
mKIAA2 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 VFCLSNSCGDVYLFQATSQTDLENWVTAIHSACASLFAKKHGKEDTVRLLKSQTRSLLQK
590 600 610 620 630 640
670 680 690 700 710 720
mKIAA2 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 IDMDSKMKKMAELQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGEL
650 660 670 680 690 700
730 740 750 760 770 780
mKIAA2 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
gi|741 PNPKSLLAATSRPSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFS
710 720 730 740 750 760
790 800 810 820 830 840
mKIAA2 SLKGLDTLARKGREKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSAL
:::::::::::::::::::::.
gi|741 SLKGLDTLARKGREKRASITQVSS
770 780
>>gi|57997048|emb|CAB59259.2| hypothetical protein [Homo (1013 aa)
initn: 5083 init1: 4649 opt: 5102 Z-score: 5411.5 bits: 1013.6 E(): 0
Smith-Waterman score: 5620; 84.073% identity (92.664% similar) in 1036 aa overlap (703-1731:1-1013)
680 690 700 710 720 730
mKIAA2 LQLSVVSDPKNRKAIENQIRQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAATSR
:::::::::::::::::::::::::::.::
gi|579 MDLFRMRCYLASLQGGELPNPKSLLAAASR
10 20 30
740 750 760 770 780 790
mKIAA2 PSKLALGRLGVLSVSSFHALVCSRDDSTLRKRTLSLTQRGKSKKGIFSSLKGLDTLARKG
::::::::::.::::::::::::::::.::::::::::::..::::::::::::::::::
gi|579 PSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRNKKGIFSSLKGLDTLARKG
40 50 60 70 80 90
800 810 820 830 840 850
mKIAA2 REKRASITQMFDSSHSHGFLGTQLPQKSTNSNKAHDLHLYGSAVDSALRDSMWEVQTYVH
.::: ::::. .: ::.:::.::.. ::. ::.:::::
gi|579 KEKRPSITQV-----------DEL------------LHIYGSTVDGVPRDNAWEIQTYVH
100 110 120
860 870 880 890 900 910
mKIAA2 FQDNEGVTVTIKPEHRVEDVLALACKMRQLEPTHYGLQLRKVVDKSVEWCVPALYEYMQE
::::.:::: :::::::::.:.::::::::::.::::::::.:: .::.:.:: :::::.
gi|579 FQDNHGVTVGIKPEHRVEDILTLACKMRQLEPSHYGLQLRKLVDDNVEYCIPAPYEYMQQ
130 140 150 160 170 180
920 930 940 950 960 970
mKIAA2 QVYDEIEVFPLSVYDVQLTKTGDMTDFGFAVTVQVDEHQHLNRIFISDVLPDSLAYGGGL
:::::::::::.::::::::::.. :::::::.::::.:::.::::::::::.:::: ::
gi|579 QVYDEIEVFPLNVYDVQLTKTGSVCDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGL
190 200 210 220 230 240
980 990 1000 1010 1020 1030
mKIAA2 RKGNEITSLNGEPVSDLDIQQMEALFSEKSVGLTLVARPVTTRRTLCASWSDSDLFSRDQ
:::::: .:::: :::::..:::::::::::::::.::: :. :::.::::::::::::
gi|579 RKGNEIMTLNGEAVSDLDLKQMEALFSEKSVGLTLIARPPDTKATLCTSWSDSDLFSRDQ
250 260 270 280 290 300
1040 1050 1060 1070 1080 1090
mKIAA2 KSLPPSPNQSQLLEEFLDNFRKTATSDFSNVPEITTGLKRSQTEGTLDQVPHREKMEQTF
::: : ::::::::::::::.:....::::::.::::::::::.:::::: :::::::::
gi|579 KSLLPPPNQSQLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTDGTLDQVSHREKMEQTF
310 320 330 340 350 360
1100 1110 1120 1130 1140 1150
mKIAA2 LSADQIAELCRDLNNTHTNSMEAPTESHDPPPRPLARHLSDADRLRKVIQELVDTEKSYV
::.::. :::..:....:.::.: :..::::::::::::::::::::::::::::::::
gi|579 RSAEQITALCRSFNDSQANGMEGPRENQDPPPRPLARHLSDADRLRKVIQELVDTEKSYV
370 380 390 400 410 420
1160 1170 1180 1190 1200 1210
mKIAA2 KDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDAISASSDFSVLE
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::..::
gi|579 KDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLE
430 440 450 460 470 480
1220 1230 1240 1250 1260 1270
mKIAA2 TPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQRVLERAKTDKAFKAFLDARNPTK
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
gi|579 TPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTK
490 500 510 520 530 540
1280 1290 1300 1310 1320 1330
mKIAA2 QHSSTLESYLIKPVQRVLKYPLLLKELVSLTDHESEEHYHLTEALKAMEKVASHINEMQK
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
gi|579 QHSSTLESYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQK
550 560 570 580 590 600
1340 1350 1360 1370 1380 1390
mKIAA2 IYEDYGMVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDIELTVFVF
:::::: :::::::::::::::::::::::::::::::::::::::::::::.:::::::
gi|579 IYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGKARKDLELTVFVF
610 620 630 640 650 660
1400 1410 1420 1430 1440 1450
mKIAA2 KRAVILVYKENCKLKKKLPSNSRPAHNSADLDPFKFRWLIPISALQVRLGNTAGTENNST
::::::::::::::::::::::::::::.:::::::::::::::::::::: :::::::
gi|579 KRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSI
670 680 690 700 710 720
1460 1470 1480 1490 1500 1510
mKIAA2 WELIHTKSEIEGRPETIFQLCCSDSENKTSIVKVIRSILRENFRRHIKCELPLEKTCKDR
::::::::::::::::::::::::::.::.::::::::::::::::::::::::::::::
gi|579 WELIHTKSEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDR
730 740 750 760 770 780
1520 1530 1540 1550 1560 1570
mKIAA2 LVPLKNRVPVSAKLASSRSLKGLRTSSSSEWPSEPSKGNSLDSDECSLSSGTQSSGCPVA
::::::::::::::::::::: :..:::.:: .: .::. ::::: ::::::::::::.:
gi|579 LVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSLSSGTQSSGCPTA
790 800 810 820 830 840
1580 1590 1600 1610 1620 1630
mKIAA2 ESRRDSKSTELEKDAQEGLAEFPDGLIKESDILSDEDEDFHHPLKQGSPTKDIELQFQRL
:.:.::::: : . :::.: :.::::::::::::.: .. .::::::::::.:::::
gi|579 EGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRL
850 860 870 880 890 900
1640 1650 1660 1670 1680
mKIAA2 KISEESDVHPVG-QQPLTESGE------QPKLVRGHFCPIKRKANSTKRGRGTLLKAQTR
.:::. :::: . ::: :::: ::::::::::::::::::::: :::::::: :
gi|579 RISEDPDVHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIR
910 920 930 940 950 960
1690 1700 1710 1720 1730
mKIAA2 HQSLDSHPETASIDLNLVLEREFSVQSLTSVVNEEGFYETQSHGKS
::::::. :.:.:::: :::::::::::::::.:: ::::.:::::
gi|579 HQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECFYETESHGKS
970 980 990 1000 1010
1731 residues in 1 query sequences
2727779818 residues in 7921681 library sequences
Tcomplib [34.26] (2 proc)
start: Mon Mar 16 19:08:29 2009 done: Mon Mar 16 19:19:56 2009
Total Scan time: 1465.210 Total Display time: 1.250
Function used was FASTA [version 34.26.5 April 26, 2007]