FASTA searches a protein or DNA sequence data bank
version 3.4t11 Apr 17, 2002
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
../query/mKIAA0357.ptfa, 1471 aa
vs ./tmplib.26680 library
1767546 residues in 2168 sequences
Expectation_n fit: rho(ln(x))= 3.8472+/-0.00398; mu= 23.2781+/- 0.267
mean_var=79.9991+/-17.959, 0's: 0 Z-trim: 4 B-trim: 0 in 0/36
Lambda= 0.1434
FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 40, opt: 28, open/ext: -10/-2, width: 16
The best scores are: opt bits E(2168)
mKIAA3028 ( 1661 res) mtg01195 (1661) 2513 531 6.5e-151
mKIAA0325 ( 1999 res) mbg00515 (1999) 278 69 1.1e-11
mKIAA1899 ( 828 res) mph04252 ( 828) 161 44 0.00013
>>mKIAA3028 ( 1661 res) mtg01195 (1661 aa)
initn: 2510 init1: 2510 opt: 2513 Z-score: 2801.7 bits: 531.2 E(): 6.5e-151
Smith-Waterman score: 2513; 70.414% identity (70.414% ungapped) in 507 aa overlap (965-1471:1-507)
940 950 960 970 980 990
mKIAA0 WKDGLFSSIMRELAIISHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNP
:::::::::::::::::::::::::::::
mKIAA3 DPMWIESLNTVMDDNKVLTLASNERIPLNR
10 20 30
1000 1010 1020 1030 1040 1050
mKIAA0 TMRLLFEISHLRTATPATVSRAGILYINPADLGWNPPVSSWIDQREVQTERANLTILFDK
::::.::::::::::::::::::::::::::::::: :::::..:.::.:.::: :::::
mKIAA3 TMRLVFEISHLRTATPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLIILFDK
40 50 60 70 80 90
1060 1070 1080 1090 1100 1110
mKIAA0 YLPTCLDTLRTRFKKIIPVPEQSMIQMLCYLLECLLTKEDIPADCPKEIYELYFVFAAIW
::::::: :: ::.: :::: ..:: . ::::::::... : : :::.:::::::: .:
mKIAA3 YLPTCLDKLRIGFKRITPVPEITVIQTILYLLECLLTEKNAPPDSPKELYELYFVFACFW
100 110 120 130 140 150
1120 1130 1140 1150 1160 1170
mKIAA0 AFGSAVIQDQLVDYRAEFSKWWLTEFKTVKFPSQGTVFDYYIDPETKKFEPWAKLIPQFE
:::.:..::::.:::.::::::..::::.:.:::::.:::::::::::: ::. .:.::
mKIAA3 AFGGAMFQDQLIDYRVEFSKWWINEFKTIKLPSQGTIFDYYIDPETKKFLPWTDKVPNFE
160 170 180 190 200 210
1180 1190 1200 1210 1220 1230
mKIAA0 FDPEMPLQACLVHTSETIRVCYFMERLMQWRRPVMLVGPAGSGKSVLVGAKLSSLNPEEY
.::..:::: ::::.::::. ::.. ::. :::::: ::.:::::.: :: .:. ..:
mKIAA3 LDPDIPLQASLVHTTETIRIRYFIDLLMEKAWPVMLVGNAGTGKSVLMGDKLENLSTDDY
220 230 240 250 260 270
1240 1250 1260 1270 1280 1290
mKIAA0 MVKNVPFNYYTTSAMLQAVLEKPLEKKAGRNYGPPGNRKLIYFIDDMNMPEVDAYGTVQP
.:. ::::.::::::::.:::::::::.::::::::..::::::::::::::: :::: :
mKIAA3 LVQAVPFNFYTTSAMLQGVLEKPLEKKSGRNYGPPGTKKLIYFIDDMNMPEVDKYGTVAP
280 290 300 310 320 330
1300 1310 1320 1330 1340 1350
mKIAA0 HTVIRQHLDYGHWYDRNKLSLKEIMNVQYISCMNPTAGSFTINPRLQRHFSVFALCFPGA
::.::::.:. :::::.::.::.. : ::..:::::.:::::.::::::: :::. :::
mKIAA3 HTLIRQHMDHRHWYDRQKLTLKDVHNCQYVACMNPTSGSFTIDPRLQRHFCVFAVSFPGQ
340 350 360 370 380 390
1360 1370 1380 1390 1400 1410
mKIAA0 DALSSIYSTILTHHLKFGNFPTTLQKSIPPLINLAVTFHQKIATTFLPTAIKFHYIFNLR
.::.:::.:::..::.: . : ..:. :.. :...:::...::::::::::::::::
mKIAA3 EALTSIYNTILAQHLSFRSAPLVIQRLSSHLVTAALALHQKVSATFLPTAIKFHYIFNLR
400 410 420 430 440 450
1420 1430 1440 1450 1460 1470
mKIAA0 DFANIFQGILFSSVECVKSTQDLVKLYLHESSRVYRDKMVEEKDFNLFDKIQTEFLK
:..:::::::::..: .:. :::.:.:::. ::: ::::.::: . . .. .:
mKIAA3 DLSNIFQGILFSTAEILKTPLDLVRLWLHEAERVYGDKMVDEKDQETLHRVTIASVKKFF
460 470 480 490 500 510
mKIAA3 DDLGEENLFAKPNIFCHFTQGIGDPKYFPVTDVAQLNKLLKDVLDSYNEVNAVMNLVLFE
520 530 540 550 560 570
>>mKIAA0325 ( 1999 res) mbg00515 (1999 aa)
initn: 177 init1: 132 opt: 278 Z-score: 302.1 bits: 69.0 E(): 1.1e-11
Smith-Waterman score: 278; 26.667% identity (27.957% ungapped) in 195 aa overlap (1274-1464:12-201)
1250 1260 1270 1280 1290 1300
mKIAA0 YTTSAMLQAVLEKPLEKKAGRNYGPPGNRKLIYFIDDMNMPEVDAYGTVQPHTVIRQHLD
:. : :..:.:..: ::: . . ::: ..
mKIAA0 VVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVE
10 20 30 40
1310 1320 1330 1340 1350 1360
mKIAA0 YGHWYDRNKLSLKEIMNVQYI-SCMNPT-AGSFTINPRLQRHFSVFALCFPGADALSSIY
.: .: . . .. .:.. .: :: : .. :. :: : . .:: .:..::
mKIAA0 HGGFYRTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIY
50 60 70 80 90 100
1370 1380 1390 1400 1410 1420
mKIAA0 STILTHHLKFGNFPTTLQKSIPPLINLAVTFHQKIATTFLPTAIKFHYIFNLRDFANIFQ
.:. :.. .:. :. :: : :. : . . :::.. :... .
mKIAA0 GTFNRAMLRL--IPS-LRTYAEPLTAAMVEFYTMSQERFTQDT-QPHYIYSPREMTRWVR
110 120 130 140 150
1430 1440 1450 1460 1470
mKIAA0 GILFSSVECVKS--TQDLVKLYLHESSRVYRDKMVEEKDFNLFDKIQTEFLK
:: : ... ... .. :.... ::. :...:..::... :.
mKIAA0 GI-FEALRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDMVALKHFPNIDK
160 170 180 190 200 210
mKIAA0 EKAMSRPILYSNWLSKDYIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRID
220 230 240 250 260 270
>>mKIAA1899 ( 828 res) mph04252 (828 aa)
initn: 290 init1: 161 opt: 161 Z-score: 175.1 bits: 44.2 E(): 0.00013
Smith-Waterman score: 280; 25.148% identity (28.146% ungapped) in 338 aa overlap (89-399:419-747)
60 70 80 90 100 110
mKIAA0 HPVLSFLYRWIYDGELEDTYHEFFVASDPTVKTDRLWHDKYTLRKSMIPSFITMDQSRKV
:. :. ... .:. . .:. .
mKIAA1 RDAERKSLYTLFLESIQLRLQHGEDSAPHIVNEDQTTKENLIKMQSIAERHLELDDIHDP
390 400 410 420 430 440
120 130 140 150 160 170
mKIAA0 LLIGKSINF----LHQVCHDQTPTTKMIAVTKSAESPRDAADLFTDLENAFQGKIDAAYF
:: .::: :.: . . : : .:.:: . .: :.. . .:: :.
mKIAA1 LL---AINFARLYLEQSDFHEKFAGGDICVDRSSESVTCQTFELT-LRSCLYPHIDKQYL
450 460 470 480 490 500
180 190 200 210 220 230
mKIAA0 ETSKYLLDVLNKKYSLLEHMQAMRRYLLLGQGDFIRHLMDLLKPELVRPATTLYQHNLTG
. :...:.. . :.:..:::: ..:. :: . .. . . .: : .:. ..
mKIAA1 HCCGNLMQTLKRDFRLVEYLQAMRNFFLMEGGDTMYDFYTSIFDK-IREKET-WQN--VS
510 520 530 540 550 560
240 250 260 270 280
mKIAA0 ILETAVRATNAQFDSPEILKRLDVRLLEVSPGDTGWDVFSLD-----YHVDGPIATVFTR
.:.. .. . .: :: ::.. . .:. : :: :.: :. :..
mKIAA1 FLNVQLQEAVGQ-RYPEDSLRLSISFENVDTTKKKLPVHILDGLTLSYKVPWPVDIVISV
570 580 590 600 610
290 300 310 320 330
mKIAA0 ECMSHYLRVFNFLWRAKRMEYILTDIRKGHMCNA----KLLRNMP-------EFSGV---
::.. : .:: .: . : .: : . :.. :: . ...: .:.
mKIAA1 ECQKIYNQVFLLLLQIKWAKYSLDVLLFGELGNAAERSQAKEDIPRDQDTPSQFGPPKES
620 630 640 650 660 670
340 350 360 370 380 390
mKIAA0 ----LHQCHILASEMVHFIHQMQYYITFEVLECSWDELWNRVQQAQDLDHIIAAHEAFLN
.:. .: ...::..... :: ..:. . :. ..:..:.:::..: : .:.
mKIAA1 LRQQIHRMFLLRVKLMHFVNSLHNYIMTRILHSTGLEFQHQVEEAKDLDQLIKIHYRYLS
680 690 700 710 720 730
400 410 420 430 440 450
mKIAA0 TITSRCLLDSNSRVLLNQLRAVFDQIIELQNAQDVMYRAALEELQRRLQFEEKKKQREIE
:: .::::
mKIAA1 TIHDRCLLREKVSFVKEAIMKVLNLALMFAEGWQAGLGAWQMESIEKMESDFKNCHMFLV
740 750 760 770 780 790
1471 residues in 1 query sequences
1767546 residues in 2168 library sequences
Scomplib [34t11]
start: Mon Mar 27 10:18:43 2006 done: Mon Mar 27 10:18:45 2006
Scan time: 1.230 Display time: 0.240
Function used was FASTA [version 3.4t11 Apr 17, 2002]