Comparison of KIAA cDNA sequences between mouse and human (KIAA0369)
<< Original sequence data >>
mouse mKIAA0369 (mbg01404) length: 5249 bp
human KIAA0369 (hh00177) length: 5703 bp
<< Aligned sequence information (excl. stop, if exists.) >>
----------------------------------------------------------
length #match #mismatch %diff
----------------------------------------------------------
DNA
CDS1 : 2278 1947 331 14.53
Total: 2278 1947 331 14.53
amino acid
CDS1 : 764 698 66 8.64
Total: 764 698 66 8.64
----------------------------------------------------------
<< Alignment region (incl. stop, if exists.) >>
----------------------------------------------------------
cDNA cDNA original amino acid
----------------------------------------------------------
CDS1 : mouse 48 - 2354 48 - 2423 1 - 769
human 66 - 2357 18 - 2402 17 - 780
----------------------------------------------------------
<< Alignment >>
*--[ CDS1 ]--*
1 ----+----*----+----*----+----*----+----*----+----* 50
1 G P A P A H Q . C T S G R S F Q T 16
mbg01404 48 GGACCAGCTCCAGCGCATCAG...TGCACTAGCGGTCGCAGCTTCCAGAC 94
|| || || | || | ||| |||| || | | | |
hh00177 66 GGCCCCGCCGCCGCCCCCCAGCCCTGCAGCCCCGCAGCCCCGGCCGCGCC 115
17 G P A A A P Q P C S P A A P A A P 33
51 ----+----*----+----*----+----*----+----*----+----* 100
17 L V L R S P S R A Q P G E D S S S 33
mbg01404 95 GCTCGTGCTCCGCAGCCCCAGCCGCGCCCAGCCCGGCGAGGACAGCTCCA 144
||||| | | || || | | | |
hh00177 116 C............AGCCCGGCGAGGACAGCACCAGGAGGCGGCCCCCAGC 153
34 . . . . S P A R T A P G G G P Q R 46
101 ----+----*----+----*----+----*----+----*----+----* 150
34 S R P Q T T Q P P P A T G S I S 49
mbg01404 145 GCAGCCGGCCACAGACAACCCAGCCTCCACCCGCGACCGGTTCCATAAGC 194
|| ||| | | | | || || ||||| | | |||
hh00177 154 GCGGCCACAAAGACCCCCGGCGGCGTCTCTCCGCGGACCGGTCCTACTTG 203
47 G H K D P R R R L S A D R S Y L 62
151 ----+----*----+----*----+----*----+----*----+----* 200
50 K P A M S F G R D M E L E H F D E 66
mbg01404 195 AAGCCAGCCATGTCGTTCGGCAGAGATATGGAGTTGGAGCATTTTGATGA 244
||| | |||||| ||||||||||| |||||| ||||||| || || ||
hh00177 204 AAGTCCATCATGTCCTTCGGCAGAGACATGGAGCTGGAGCACTTCGACGA 253
63 K S I M S F G R D M E L E H F D E 79
201 ----+----*----+----*----+----*----+----*----+----* 250
67 R D K A Q R Y S R G S R V N G L P 83
mbg01404 245 GCGGGACAAGGCGCAGAGGTACAGCAGGGGGTCCCGTGTGAATGGCCTGC 294
|||||| ||||||||||| |||||| | ||||| || ||||| |||||||
hh00177 254 GCGGGATAAGGCGCAGAGATACAGCCGAGGGTCGCGGGTGAACGGCCTGC 303
80 R D K A Q R Y S R G S R V N G L P 96
251 ----+----*----+----*----+----*----+----*----+----* 300
84 S P T H S A H C S F Y R T R T L 99
mbg01404 295 CCAGCCCCACACACAGCGCCCACTGCAGCTTCTACCGCACCCGCACCCTG 344
| ||||| || ||||||||||||||||||||||||||||||||||| |||
hh00177 304 CGAGCCCGACGCACAGCGCCCACTGCAGCTTCTACCGCACCCGCACGCTG 353
97 S P T H S A H C S F Y R T R T L 112
301 ----+----*----+----*----+----*----+----*----+----* 350
100 Q T L S S E K K A K K V R F Y R N 116
mbg01404 345 CAGACGCTCAGCTCCGAGAAGAAAGCCAAGAAGGTTCGATTCTACAGAAA 394
||||||||||||||||||||||| |||||||| ||||| ||||| ||||
hh00177 354 CAGACGCTCAGCTCCGAGAAGAAGGCCAAGAAAGTTCGTTTCTATCGAAA 403
113 Q T L S S E K K A K K V R F Y R N 129
351 ----+----*----+----*----+----*----+----*----+----* 400
117 G D R Y F K G I V Y A I S P D R F 133
mbg01404 395 TGGTGACCGCTACTTCAAAGGAATTGTGTATGCCATCTCCCCAGACCGCT 444
|| || || ||||||||||| |||||||||||||||||||||||||| |
hh00177 404 CGGAGATCGATACTTCAAAGGGATTGTGTATGCCATCTCCCCAGACCGGT 453
130 G D R Y F K G I V Y A I S P D R F 146
401 ----+----*----+----*----+----*----+----*----+----* 450
134 R S F E A L L A D L T R T L S D 149
mbg01404 445 TCAGATCTTTCGAGGCCCTGCTGGCTGATTTGACCCGAACTCTCTCGGAT 494
|| ||||||| |||||||||||||||||||||||||||||||| ||||||
hh00177 454 TCCGATCTTTTGAGGCCCTGCTGGCTGATTTGACCCGAACTCTGTCGGAT 503
147 R S F E A L L A D L T R T L S D 162
451 ----+----*----+----*----+----*----+----*----+----* 500
150 N V N L P Q G V R T I Y T I D G L 166
mbg01404 495 AATGTGAATTTGCCCCAGGGGGTGAGAACCATCTACACCATCGATGGACT 544
|| ||||||||||||||||| |||||||| ||||||||||| ||||| ||
hh00177 504 AACGTGAATTTGCCCCAGGGAGTGAGAACAATCTACACCATTGATGGGCT 553
163 N V N L P Q G V R T I Y T I D G L 179
501 ----+----*----+----*----+----*----+----*----+----* 550
167 K K I S S L D Q L V E G E S Y V C 183
mbg01404 545 CAAGAAGATCTCCAGCCTGGACCAGCTGGTGGAAGGTGAAAGCTATGTCT 594
||||||||| |||||||||||||| ||||||||||| || || ||||| |
hh00177 554 CAAGAAGATTTCCAGCCTGGACCAACTGGTGGAAGGAGAGAGTTATGTAT 603
180 K K I S S L D Q L V E G E S Y V C 196
551 ----+----*----+----*----+----*----+----*----+----* 600
184 G S I E P F K K L E Y T K N V N 199
mbg01404 595 GCGGCTCCATCGAGCCCTTTAAGAAGCTGGAGTACACCAAGAATGTGAAC 644
| |||||||| |||||||| ||||| ||||||||||||||||||||||||
hh00177 604 GTGGCTCCATAGAGCCCTTCAAGAAACTGGAGTACACCAAGAATGTGAAC 653
197 G S I E P F K K L E Y T K N V N 212
601 ----+----*----+----*----+----*----+----*----+----* 650
200 P N W S V N V K T T S A S R A V S 216
mbg01404 645 CCCAACTGGTCAGTGAACGTCAAGACCACCTCAGCCTCCCGCGCAGTGTC 694
||||||||||| |||||||||||||||||||| || || || ||||||||
hh00177 654 CCCAACTGGTCGGTGAACGTCAAGACCACCTCGGCTTCTCGGGCAGTGTC 703
213 P N W S V N V K T T S A S R A V S 229
651 ----+----*----+----*----+----*----+----*----+----* 700
217 S L A T A K G G P S E V R E N K D 233
mbg01404 695 TTCTTTGGCCACTGCCAAGGGTGGGCCTTCGGAGGTTCGGGAGAATAAGG 744
||| ||||||||||||| || | ||||| ||||| || ||||||||||
hh00177 704 TTCACTGGCCACTGCCAAAGGAAGCCCTTCAGAGGTGCGAGAGAATAAGG 753
230 S L A T A K G S P S E V R E N K D 246
701 ----+----*----+----*----+----*----+----*----+----* 750
234 F I R P K L V T I I R S G V K P 249
mbg01404 745 ATTTCATTCGACCCAAGCTGGTCACCATCATCAGAAGTGGGGTGAAGCCA 794
|||||||||| ||||||||||||||||||||||||||||| |||||||||
hh00177 754 ATTTCATTCGGCCCAAGCTGGTCACCATCATCAGAAGTGGCGTGAAGCCA 803
247 F I R P K L V T I I R S G V K P 262
751 ----+----*----+----*----+----*----+----*----+----* 800
250 R K A V R I L L N K K T A H S F E 266
mbg01404 795 CGGAAGGCTGTCAGAATCCTGCTGAACAAGAAGACGGCTCACTCCTTCGA 844
||||| |||||||| || |||||||||||||| |||||||| ||||| ||
hh00177 804 CGGAAAGCTGTCAGGATTCTGCTGAACAAGAAAACGGCTCATTCCTTTGA 853
263 R K A V R I L L N K K T A H S F E 279
801 ----+----*----+----*----+----*----+----*----+----* 850
267 Q V L T D I T D A I K L D S G V V 283
mbg01404 845 GCAGGTTCTCACTGACATTACCGACGCTATCAAGCTGGACTCCGGTGTGG 894
|||||| ||||| || || ||||| || |||||||||||||| || ||||
hh00177 854 GCAGGTCCTCACCGATATCACCGATGCCATCAAGCTGGACTCGGGAGTGG 903
280 Q V L T D I T D A I K L D S G V V 296
851 ----+----*----+----*----+----*----+----*----+----* 900
284 K R L Y T L D G K Q V M C L Q D 299
mbg01404 895 TGAAGCGCCTGTACACTCTGGATGGGAAGCAGGTGATGTGCCTTCAGGAC 944
|||| ||||||||||| |||||||||| |||||||||||||||||||||
hh00177 904 TGAAACGCCTGTACACGTTGGATGGGAAACAGGTGATGTGCCTTCAGGAC 953
297 K R L Y T L D G K Q V M C L Q D 312
901 ----+----*----+----*----+----*----+----*----+----* 950
300 F F G D D D I F I A C G P E K F R 316
mbg01404 945 TTTTTTGGTGACGATGACATTTTTATTGCATGTGGACCAGAGAAGTTCCG 994
||||||||||| |||||||||||||||||||||||||| |||||||||||
hh00177 954 TTTTTTGGTGATGATGACATTTTTATTGCATGTGGACCGGAGAAGTTCCG 1003
313 F F G D D D I F I A C G P E K F R 329
951 ----+----*----+----*----+----*----+----*----+----* 1000
317 Y Q D D F L L D E S E C R V V K S 333
mbg01404 995 TTACCAGGATGATTTCTTGCTAGATGAAAGTGAATGTCGAGTGGTGAAAT 1044
||||||||||||||||||||||||||||||||||||||||||||| || |
hh00177 1004 TTACCAGGATGATTTCTTGCTAGATGAAAGTGAATGTCGAGTGGTAAAGT 1053
330 Y Q D D F L L D E S E C R V V K S 346
1001 ----+----*----+----*----+----*----+----*----+----* 1050
334 T S Y T K I A S A S R R G T T K 349
mbg01404 1045 CAACTTCTTACACCAAAATAGCATCAGCGTCCCGCAGAGGCACAACCAAG 1094
| |||||||||||||||||||| ||| | |||||||| |||| ||||||
hh00177 1054 CCACTTCTTACACCAAAATAGCTTCATCATCCCGCAGGAGCACCACCAAG 1103
347 T S Y T K I A S S S R R S T T K 362
1051 ----+----*----+----*----+----*----+----*----+----* 1100
350 S P G P S R R S K S P A S T S S V 366
mbg01404 1095 AGCCCAGGACCTTCCCGGAGAAGCAAGTCCCCAGCCTCCACCAGCTCAGT 1144
||||||||||| ||| || | ||||||||||| |||||||||||||||||
hh00177 1104 AGCCCAGGACCGTCCAGGCGTAGCAAGTCCCCTGCCTCCACCAGCTCAGT 1153
363 S P G P S R R S K S P A S T S S V 379
1101 ----+----*----+----*----+----*----+----*----+----* 1150
367 N G T P G S Q L S T P R S G K S P 383
mbg01404 1145 TAATGGAACCCCTGGTAGTCAGCTCTCTACTCCACGCTCGGGCAAGTCAC 1194
||||||||||||||||||||||||||||||||| ||||| |||||||| |
hh00177 1154 TAATGGAACCCCTGGTAGTCAGCTCTCTACTCCGCGCTCAGGCAAGTCGC 1203
380 N G T P G S Q L S T P R S G K S P 396
1151 ----+----*----+----*----+----*----+----*----+----* 1200
384 S P S P T S P G S L R K Q R I S 399
mbg01404 1195 CAAGTCCATCACCCACCAGCCCAGGAAGCCTGCGGAAGCAGAGGATCTCT 1244
|||| |||||||||||||||||||||||||||||||||||||||| ||||
hh00177 1204 CAAGCCCATCACCCACCAGCCCAGGAAGCCTGCGGAAGCAGAGGAGCTCT 1253
397 S P S P T S P G S L R K Q R S S 412
1201 ----+----*----+----*----+----*----+----*----+----* 1250
400 Q H G G S S T S L S S T K V C S S 416
mbg01404 1245 CAGCATGGCGGCTCCTCGACTTCACTTTCATCCACTAAAGTTTGCAGCTC 1294
||||||||||||||||| || |||||| | ||||| ||||| ||||||||
hh00177 1254 CAGCATGGCGGCTCCTCTACGTCACTTGCGTCCACCAAAGTCTGCAGCTC 1303
413 Q H G G S S T S L A S T K V C S S 429
1251 ----+----*----+----*----+----*----+----*----+----* 1300
417 M D E N D G P G E E E S E E G F Q 433
mbg01404 1295 AATGGATGAGAATGATGGCCCTGGGGAAGAAGAGTCTGAGGAAGGCTTCC 1344
||||||||||| ||||||||||| ||||||| ||| |||||||||||||
hh00177 1304 GATGGATGAGAACGATGGCCCTGGAGAAGAAGTGTCGGAGGAAGGCTTCC 1353
430 M D E N D G P G E E V S E E G F Q 446
1301 ----+----*----+----*----+----*----+----*----+----* 1350
434 I P A T I T E R Y K V G R T I G 449
mbg01404 1345 AGATTCCTGCCACAATAACAGAGAGATACAAAGTCGGGAGAACAATAGGA 1394
||||||| || ||||||||||| |||| |||||||| ||||||||||||
hh00177 1354 AGATTCCAGCTACAATAACAGAACGATATAAAGTCGGAAGAACAATAGGA 1403
447 I P A T I T E R Y K V G R T I G 462
1351 ----+----*----+----*----+----*----+----*----+----* 1400
450 D G N F A V V K E C I E R S T A R 466
mbg01404 1395 GACGGAAATTTTGCTGTTGTCAAGGAATGTATAGAGAGGTCGACTGCTCG 1444
|| ||||||||||||||||||||||||||| |||| || ||||||||| |
hh00177 1404 GATGGAAATTTTGCTGTTGTCAAGGAATGTGTAGAAAGATCGACTGCTAG 1453
463 D G N F A V V K E C V E R S T A R 479
1401 ----+----*----+----*----+----*----+----*----+----* 1450
467 E Y A L K I I K K S K C R G K E H 483
mbg01404 1445 GGAGTATGCCCTGAAAATCATCAAGAAAAGCAAATGCCGAGGCAAAGAGC 1494
||||| || |||||||| ||||||||||||||||| |||||||||||||
hh00177 1454 AGAGTACGCTCTGAAAATTATCAAGAAAAGCAAATGTCGAGGCAAAGAGC 1503
480 E Y A L K I I K K S K C R G K E H 496
1451 ----+----*----+----*----+----*----+----*----+----* 1500
484 M I Q N E V S I L R R V K H P N 499
mbg01404 1495 ACATGATCCAGAACGAGGTCTCCATCCTACGGAGGGTGAAGCACCCCAAC 1544
||||||||||||| || || || || || | || |||||||| |||||
hh00177 1504 ACATGATCCAGAATGAAGTGTCTATTTTAAGAAGAGTGAAGCATCCCAAT 1553
497 M I Q N E V S I L R R V K H P N 512
1501 ----+----*----+----*----+----*----+----*----+----* 1550
500 I V L L I E E M D V P T E L Y L V 516
mbg01404 1545 ATTGTCCTCCTGATTGAAGAGATGGATGTGCCGACTGAACTGTATCTTGT 1594
|| || || |||||||| |||||||||||||| |||||||||||||||||
hh00177 1554 ATCGTTCTTCTGATTGAGGAGATGGATGTGCCAACTGAACTGTATCTTGT 1603
513 I V L L I E E M D V P T E L Y L V 529
1551 ----+----*----+----*----+----*----+----*----+----* 1600
517 M E L V K G G D L F D A I T S T S 533
mbg01404 1595 AATGGAATTAGTGAAGGGTGGAGACCTTTTCGATGCCATCACCTCCACTA 1644
||||||||||| ||||| ||||||||||| |||||||| || |||||||
hh00177 1604 CATGGAATTAGTAAAGGGGGGAGACCTTTTTGATGCCATTACTTCCACTA 1653
530 M E L V K G G D L F D A I T S T N 546
1601 ----+----*----+----*----+----*----+----*----+----* 1650
534 K Y T E R D A S G M L Y N L A S 549
mbg01404 1645 GCAAATACACAGAGAGAGATGCCAGCGGGATGCTGTACAACCTGGCCAGC 1694
||||||||| |||||||| ||||| ||||||||||||||||| ||||||
hh00177 1654 ACAAATACACCGAGAGAGACGCCAGTGGGATGCTGTACAACCTAGCCAGC 1703
547 K Y T E R D A S G M L Y N L A S 562
1651 ----+----*----+----*----+----*----+----*----+----* 1700
550 A I K Y L H S L N I V H R D I K P 566
mbg01404 1695 GCCATCAAATACCTGCACAGCCTGAACATCGTCCACCGTGACATCAAGCC 1744
||||||||||||||||| ||||||||||||||||||||||| ||||||||
hh00177 1704 GCCATCAAATACCTGCATAGCCTGAACATCGTCCACCGTGATATCAAGCC 1753
563 A I K Y L H S L N I V H R D I K P 579
1701 ----+----*----+----*----+----*----+----*----+----* 1750
567 E N L L V Y E H Q D G S K S L K L 583
mbg01404 1745 AGAGAATCTGCTGGTGTATGAGCACCAGGATGGCAGTAAGTCACTCAAGT 1794
|||||| |||||||||||||||||||| |||||||| || ||||| |||
hh00177 1754 AGAGAACCTGCTGGTGTATGAGCACCAAGATGGCAGCAAATCACTGAAGC 1803
580 E N L L V Y E H Q D G S K S L K L 596
1751 ----+----*----+----*----+----*----+----*----+----* 1800
584 G D F G L A T I V D G P L Y T V 599
mbg01404 1795 TGGGTGACTTTGGCCTGGCCACAATTGTCGACGGCCCCCTGTACACAGTC 1844
||||||||||||| |||||||| ||||| |||||||||||||||||||||
hh00177 1804 TGGGTGACTTTGGACTGGCCACCATTGTAGACGGCCCCCTGTACACAGTC 1853
597 G D F G L A T I V D G P L Y T V 612
1801 ----+----*----+----*----+----*----+----*----+----* 1850
600 C G T P T Y V A P E I I A E T G Y 616
mbg01404 1845 TGTGGCACCCCAACATATGTGGCTCCAGAAATCATTGCAGAGACTGGATA 1894
||||||||||||||||| ||||||||||||||||||||||||||||||||
hh00177 1854 TGTGGCACCCCAACATACGTGGCTCCAGAAATCATTGCAGAGACTGGATA 1903
613 C G T P T Y V A P E I I A E T G Y 629
1851 ----+----*----+----*----+----*----+----*----+----* 1900
617 G L K V D I W A A G V I T Y I L L 633
mbg01404 1895 TGGCCTCAAGGTGGACATCTGGGCAGCTGGCGTGATCACTTATATCCTGC 1944
|||||||||||||||||||||||||| || || ||||||||||||||||
hh00177 1904 CGGCCTCAAGGTGGACATCTGGGCAGCAGGTGTAATCACTTATATCCTGC 1953
630 G L K V D I W A A G V I T Y I L L 646
1901 ----+----*----+----*----+----*----+----*----+----* 1950
634 C G F P P F R G . G D D Q E V L 648
mbg01404 1945 TGTGTGGCTTCCCTCCGTTCCGTGGT...GGGGATGACCAGGAGGTGCTT 1991
||||||| |||||||| |||||||| || ||||||||||||||||||
hh00177 1954 TGTGTGGTTTCCCTCCATTCCGTGGAAGTGGTGATGACCAGGAGGTGCTT 2003
647 C G F P P F R G S G D D Q E V L 662
1951 ----+----*----+----*----+----*----+----*----+----* 2000
649 F D Q I L M G Q V D F P S P Y W D 665
mbg01404 1992 TTTGACCAGATCTTGATGGGCCAAGTGGACTTTCCATCTCCGTATTGGGA 2041
||||| ||||| |||||||| || ||||||||||| ||||| || |||||
hh00177 2004 TTTGATCAGATTTTGATGGGGCAGGTGGACTTTCCTTCTCCATACTGGGA 2053
663 F D Q I L M G Q V D F P S P Y W D 679
2001 ----+----*----+----*----+----*----+----*----+----* 2050
666 N V S D S A K E L I N M M L L V N 682
mbg01404 2042 CAATGTGTCAGATTCTGCTAAGGAGCTCATCAACATGATGCTGTTGGTTA 2091
||||| || |||||||| ||||||||||| | |||||||||||||||
hh00177 2054 TAATGTTTCCGATTCTGCAAAGGAGCTCATTACCATGATGCTGTTGGTCG 2103
680 N V S D S A K E L I T M M L L V D 696
2051 ----+----*----+----*----+----*----+----*----+----* 2100
683 V D Q R F S A V Q V L E H P W V 698
mbg01404 2092 ACGTGGACCAGAGATTTTCAGCCGTGCAGGTCCTTGAGCATCCCTGGGTT 2141
| || || ||| ||||||| || || || || ||||||||||||||||||
hh00177 2104 ATGTAGATCAGCGATTTTCTGCTGTTCAAGTACTTGAGCATCCCTGGGTT 2153
697 V D Q R F S A V Q V L E H P W V 712
2101 ----+----*----+----*----+----*----+----*----+----* 2150
699 N D D G L P E N E H Q L S V A G K 715
mbg01404 2142 AATGATGATGGTCTCCCAGAAAATGAGCATCAGCTGTCAGTAGCTGGCAA 2191
||||||||||| |||||||||||||| |||||||||||||||||||| ||
hh00177 2154 AATGATGATGGCCTCCCAGAAAATGAACATCAGCTGTCAGTAGCTGGAAA 2203
713 N D D G L P E N E H Q L S V A G K 729
2151 ----+----*----+----*----+----*----+----*----+----* 2200
716 I K K H F N T G P K P S S T A A G 732
mbg01404 2192 AATCAAGAAGCATTTCAACACAGGCCCCAAGCCGAGCAGCACTGCAGCAG 2241
|| ||||||||||||||||||||||||||||||| ||||| ||||| |
hh00177 2204 GATAAAGAAGCATTTCAACACAGGCCCCAAGCCGAATAGCACAGCAGCTG 2253
730 I K K H F N T G P K P N S T A A G 746
2201 ----+----*----+----*----+----*----+----*----+----* 2250
733 V S V I A T T A L D K E R Q V F 748
mbg01404 2242 GAGTTTCTGTAATAGCAACCACCGCTCTTGATAAGGAGAGGCAGGTTTTC 2291
|||||||||| |||||| || || | | | |
hh00177 2254 GAGTTTCTGTCATAGCA.........CTGGACCACGGGTTTACCATC... 2291
747 V S V I A . . . L D H G F T I . 758
2251 ----+----*----+----*----+----*----+----*----+----* 2300
749 R R R R N Q D V R S R Y K A Q P A 765
mbg01404 2292 CGACGAAGACGCAACCAGGATGTGAGGAGCCGGTACAAGGCGCAGCCAGC 2341
|| | | ||| ||| | ||| ||||
hh00177 2292 AAGAGATCAGGGTCTTTGGAC............TACTACCAGCAACCAGG 2329
759 K R S G S L D . . . . Y Y Q Q P G 771
2301 ----+----*----+----*----+--- 2328
766 . . . . . P P E L 769
mbg01404 2342 T...............CCACCGGAATTG 2354
|||||| |||
hh00177 2330 AATGTATTGGATAAGACCACCGCTCTTG 2357
772 M Y W I R P P L L 780