FASTA searches a protein or DNA sequence data bank
 version 3.4t11 Apr 17, 2002
Please cite:
 W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

 ../query/mKIAA0832.ptfa, 466 aa
 vs ./tmplib.26680 library

1768551 residues in  2168 sequences
  Expectation_n fit: rho(ln(x))= 4.6530+/-0.00503; mu= 18.3687+/- 0.339
 mean_var=110.5020+/-24.792, 0's: 0 Z-trim: 2  B-trim: 6 in 1/35
 Lambda= 0.1220

FASTA (3.45 Mar 2002) function [optimized, BL50 matrix (15:-5)] ktup: 2
 join: 37, opt: 25, open/ext: -10/-2, width:  16
The best scores are:                                       opt bits E(2168)
mFLJ00318  ( 471 res)   mpj01782                   ( 471)  741  141 2.1e-34
mKIAA4145  ( 363 res)   mbg01377                   ( 363)  243   53 4.3e-08


>>mFLJ00318  ( 471 res)   mpj01782                        (471 aa)
 initn: 618 init1: 337 opt: 741  Z-score: 710.2  bits: 140.7 E(): 2.1e-34
Smith-Waterman score: 774;  33.032% identity (36.228% ungapped) in 442 aa overlap (51-464:36-466)

               30        40        50        60        70        80
mKIAA0 ISYLIMMLLCRMSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTM
                                     ::   ::  ...  :: ::     :  ::.
mFLJ00 DTKHFLPLDFSTQVNSSSLNSPTGRGSMAVPSLHPSLGPGIG--SPLGSPGQLHSPISTL
          10        20        30        40          50        60   

               90                   100          110       120     
mKIAA0 NGHQNGLDSP------PL------YPSAPILG---GSGPVRKLYDDCSSTIVEDPQTKCE
       ..  ::.  :      :.       :..: ::   ::  . . ..  :::    :    .
mFLJ00 SSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFGTGSPQLNSPMNPVSSTEDIKPPLGLN
            70        80        90       100       110       120   

                   130       140       150       160       170     
mKIAA0 YMLN----------SMPKRLCLVCGDIASGYHYGVASCEACKAFFNRTIQGNIEYSCPAT
        .:.          :. :..: .::: .:: :::: :::.::.::.::.. .. :.:  .
mFLJ00 GVLKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDN
           130       140       150       160       170       180   

         180       190       200       210       220       230     
mKIAA0 NECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLV
       ..: : ::.:. :: ::..::: .:: .:.:. .: ::   : . . ..:..   : .. 
mFLJ00 KDCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRG---KDRNENEVESTSSANEDM-
           190       200       210       220          230          

         240       250        260        270       280       290   
mKIAA0 QPAKKPYNKIVSHLLVAEPE-KIYAMPDPTV-PDSDIKALTTLCDLADRELVVIIGWAKH
            : .::.   :..::. . :.  .  . :.:    .:..:. ::..: ... :::.
mFLJ00 -----PVEKILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKR
          240       250       260       270       280       290    

           300       310       320       330       340       350   
mKIAA0 IPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDL
       :: :: : : ::. ::...: :.:: .  .::.. .: .. :    . ..... ::.  .
mFLJ00 IPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAI
          300       310       320       330       340       350    

            360       370       380       390       400       410  
mKIAA0 NNAIL-QLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEA
        . .: .::.:...:...: :.  :.::.: : ::  . .   :. :.. .. .:. :  
mFLJ00 FDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK
          360       370       380       390       400       410    

            420       430       440       450       460         
mKIAA0 GQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV   
        .. :.: : .:.:. :: ::. . : ..:.. .:: : .:.  ...:::::     
mFLJ00 HKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQAT
          420       430       440       450       460       470 

>>mKIAA4145  ( 363 res)   mbg01377                        (363 aa)
 initn: 221 init1: 121 opt: 243  Z-score: 237.6  bits: 52.9 E(): 4.3e-08
Smith-Waterman score: 243;  27.103% identity (29.146% ungapped) in 214 aa overlap (260-463:140-348)

     230       240       250       260       270       280         
mKIAA0 LNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIG
                                     ::.: .:.     .  .:. :.: : . . 
mKIAA4 IHVISRDQSTPIIEVEGPLLSDTHVTFKLTMPSP-MPE--YLNVHYICESASRLLFLSMH
     110       120       130       140          150       160      

     290       300       310       320         330       340       
mKIAA0 WAKHIPGFSTLSLADQMSLLQSAWMEILILGVVY--RSLSFEDELVYADDYIMDEDQ-SK
       ::. ::.:..:.   . ::... : :.. ::..   . .:.   :.   .....  : .:
mKIAA4 WARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDK
        170       180       190       200       210       220      

        350       360            370         380       390         
mKIAA0 LAGLLDLNNAILQLVKKYK----SM-KLEKE--EFVTLKAIALANSDSMHIEDVEAVQKL
       :.:  :  . ... . : .    :: ::. .  :.. ::::.: . :   .  .  ..:.
mKIAA4 LSG--DRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTGTSQIEKF
          230       240       250       260       270       280    

     400       410       420       430       440       450         
mKIAA0 QDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFL
       :.  .  ::::    . ::  : ...:. :: ::  :.. .....   : :.: . ... 
mKIAA4 QEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIP
          290       300       310       320       330       340    

     460                  
mKIAA0 EMLEAKV            
        .:.               
mKIAA4 YILKMETAEYNGQITGASL
          350       360   




466 residues in 1 query   sequences
1768551 residues in 2168 library sequences
 Scomplib [34t11]
 start: Mon Mar 27 10:29:50 2006 done: Mon Mar 27 10:29:51 2006
 Scan time:  0.680 Display time:  0.040

Function used was FASTA [version 3.4t11 Apr 17, 2002]