Miyakogusa Predicted Gene
- Lj0g3v0268489.1
BLASTP 2.2.25 [Feb-01-2011]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Query= Lj0g3v0268489.1 Non Chatacterized Hit- tr|I1M638|I1M638_SOYBN
Uncharacterized protein (Fragment) OS=Glycine max
PE=4,82.57,0,NIEMANN-PICK C1,NULL; PATCHED-RELATED,NULL;
seg,NULL,NODE_19512_length_4214_cov_79.163979.path2.1
(574 letters)
Database: trembl
41,451,118 sequences; 13,208,986,710 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
K7M447_SOYBN (tr|K7M447) Uncharacterized protein OS=Glycine max ... 920 0.0
K7M448_SOYBN (tr|K7M448) Uncharacterized protein OS=Glycine max ... 917 0.0
K7KBT5_SOYBN (tr|K7KBT5) Uncharacterized protein OS=Glycine max ... 912 0.0
B9HPX9_POPTR (tr|B9HPX9) Cholesterol transport protein OS=Populu... 740 0.0
F6I0S6_VITVI (tr|F6I0S6) Putative uncharacterized protein OS=Vit... 728 0.0
F4JTN0_ARATH (tr|F4JTN0) Patched family protein OS=Arabidopsis t... 728 0.0
R0F2L3_9BRAS (tr|R0F2L3) Uncharacterized protein OS=Capsella rub... 725 0.0
D7UDA3_VITVI (tr|D7UDA3) Putative uncharacterized protein OS=Vit... 722 0.0
M5W6J9_PRUPE (tr|M5W6J9) Uncharacterized protein OS=Prunus persi... 716 0.0
F4JTN1_ARATH (tr|F4JTN1) Patched family protein OS=Arabidopsis t... 714 0.0
K7M449_SOYBN (tr|K7M449) Uncharacterized protein OS=Glycine max ... 714 0.0
M4D2P3_BRARP (tr|M4D2P3) Uncharacterized protein OS=Brassica rap... 712 0.0
K4BVX6_SOLLC (tr|K4BVX6) Uncharacterized protein OS=Solanum lyco... 709 0.0
D7MEY0_ARALL (tr|D7MEY0) Patched family protein OS=Arabidopsis l... 697 0.0
B9H5I2_POPTR (tr|B9H5I2) Cholesterol transport protein OS=Populu... 692 0.0
I1K7C8_SOYBN (tr|I1K7C8) Uncharacterized protein OS=Glycine max ... 692 0.0
K7KHM4_SOYBN (tr|K7KHM4) Uncharacterized protein OS=Glycine max ... 687 0.0
K7KHM5_SOYBN (tr|K7KHM5) Uncharacterized protein OS=Glycine max ... 687 0.0
R0ILR5_9BRAS (tr|R0ILR5) Uncharacterized protein OS=Capsella rub... 673 0.0
B9R8N7_RICCO (tr|B9R8N7) Hedgehog receptor, putative OS=Ricinus ... 666 0.0
M4EZY9_BRARP (tr|M4EZY9) Uncharacterized protein OS=Brassica rap... 664 0.0
D7KMU0_ARALL (tr|D7KMU0) Predicted protein OS=Arabidopsis lyrata... 663 0.0
M5WD18_PRUPE (tr|M5WD18) Uncharacterized protein OS=Prunus persi... 662 0.0
F4I9G5_ARATH (tr|F4I9G5) Patched family protein OS=Arabidopsis t... 660 0.0
A5APM6_VITVI (tr|A5APM6) Putative uncharacterized protein OS=Vit... 652 0.0
M4D678_BRARP (tr|M4D678) Uncharacterized protein OS=Brassica rap... 642 0.0
Q9SVF0_ARATH (tr|Q9SVF0) Putative uncharacterized protein AT4g38... 611 e-172
K3Y4Q6_SETIT (tr|K3Y4Q6) Uncharacterized protein OS=Setaria ital... 610 e-172
M0RUG9_MUSAM (tr|M0RUG9) Uncharacterized protein OS=Musa acumina... 607 e-171
Q9SHN9_ARATH (tr|Q9SHN9) F7F22.1 OS=Arabidopsis thaliana PE=4 SV=1 603 e-170
C5YE00_SORBI (tr|C5YE00) Putative uncharacterized protein Sb06g0... 579 e-163
A9SMZ7_PHYPA (tr|A9SMZ7) Predicted protein OS=Physcomitrella pat... 573 e-161
J3M0F2_ORYBR (tr|J3M0F2) Uncharacterized protein OS=Oryza brachy... 570 e-160
Q7XUB7_ORYSJ (tr|Q7XUB7) OSJNBb0078D11.11 protein OS=Oryza sativ... 529 e-147
Q01KH5_ORYSA (tr|Q01KH5) H0409D10.4 protein OS=Oryza sativa GN=H... 528 e-147
D8S0H8_SELML (tr|D8S0H8) Putative uncharacterized protein (Fragm... 511 e-142
D8SB69_SELML (tr|D8SB69) Putative uncharacterized protein (Fragm... 508 e-141
B9FBZ9_ORYSJ (tr|B9FBZ9) Putative uncharacterized protein OS=Ory... 489 e-135
B8AT56_ORYSI (tr|B8AT56) Putative uncharacterized protein OS=Ory... 489 e-135
A9RFW8_PHYPA (tr|A9RFW8) Uncharacterized protein (Fragment) OS=P... 484 e-134
G7KFF1_MEDTR (tr|G7KFF1) Niemann-Pick C1 protein OS=Medicago tru... 447 e-123
I1PNW1_ORYGL (tr|I1PNW1) Uncharacterized protein OS=Oryza glaber... 418 e-114
M0RSW2_MUSAM (tr|M0RSW2) Uncharacterized protein OS=Musa acumina... 408 e-111
C7J1V6_ORYSJ (tr|C7J1V6) Os04g0563801 protein OS=Oryza sativa su... 351 6e-94
I0Z7Q3_9CHLO (tr|I0Z7Q3) Multidrug efflux transporter AcrB trans... 336 1e-89
I1J0L7_BRADI (tr|I1J0L7) Uncharacterized protein OS=Brachypodium... 315 3e-83
G0RBC0_HYPJQ (tr|G0RBC0) Predicted protein OS=Hypocrea jecorina ... 263 2e-67
G9MVK1_HYPVG (tr|G9MVK1) Uncharacterized protein OS=Hypocrea vir... 261 5e-67
M7ZB10_TRIUA (tr|M7ZB10) Niemann-Pick C1 protein OS=Triticum ura... 259 2e-66
M8C7J7_AEGTA (tr|M8C7J7) Niemann-Pick C1 protein OS=Aegilops tau... 258 6e-66
C5FQM2_ARTOC (tr|C5FQM2) Niemann-Pick C1 protein OS=Arthroderma ... 258 7e-66
R8BD46_9PEZI (tr|R8BD46) Putative patched sphingolipid transport... 252 2e-64
G2QH84_THIHA (tr|G2QH84) Uncharacterized protein OS=Thielavia he... 252 2e-64
R0K538_SETTU (tr|R0K538) Uncharacterized protein OS=Setosphaeria... 252 3e-64
G4UZ74_NEUT9 (tr|G4UZ74) Multidrug efflux transporter AcrB trans... 248 5e-63
F8MXC7_NEUT8 (tr|F8MXC7) Putative uncharacterized protein OS=Neu... 248 5e-63
B0Y842_ASPFC (tr|B0Y842) Patched sphingolipid transporter (Ncr1)... 248 7e-63
Q4WMG5_ASPFU (tr|Q4WMG5) Patched sphingolipid transporter (Ncr1)... 248 7e-63
L7J8J1_MAGOR (tr|L7J8J1) Niemann-Pick C1 protein OS=Magnaporthe ... 247 8e-63
L7HPU7_MAGOR (tr|L7HPU7) Niemann-Pick C1 protein OS=Magnaporthe ... 247 8e-63
G4NE97_MAGO7 (tr|G4NE97) Niemann-Pick C1 protein OS=Magnaporthe ... 247 8e-63
G0SAS3_CHATD (tr|G0SAS3) Hedgehog receptor-like protein OS=Chaet... 246 1e-62
B6HDY6_PENCW (tr|B6HDY6) Pc20g15300 protein (Precursor) OS=Penic... 246 2e-62
Q5BBG1_EMENI (tr|Q5BBG1) Putative uncharacterized protein OS=Eme... 246 2e-62
B2W9M2_PYRTR (tr|B2W9M2) Niemann-Pick C1 protein OS=Pyrenophora ... 245 4e-62
G9P5M7_HYPAI (tr|G9P5M7) Putative uncharacterized protein OS=Hyp... 244 5e-62
M0RSW1_MUSAM (tr|M0RSW1) Uncharacterized protein OS=Musa acumina... 244 7e-62
E9CWG5_COCPS (tr|E9CWG5) Patched sphingolipid transporter OS=Coc... 244 8e-62
C5PGL6_COCP7 (tr|C5PGL6) Patched family protein OS=Coccidioides ... 244 8e-62
C1G8F9_PARBD (tr|C1G8F9) Niemann-Pick C1 protein OS=Paracoccidio... 244 8e-62
F2PP73_TRIEC (tr|F2PP73) Vacuolar membrane protein OS=Trichophyt... 244 9e-62
C0S090_PARBP (tr|C0S090) Niemann-Pick C1 protein OS=Paracoccidio... 243 1e-61
J3KJB8_COCIM (tr|J3KJB8) Niemann-Pick C type protein family OS=C... 243 1e-61
E3S9W3_PYRTT (tr|E3S9W3) Putative uncharacterized protein OS=Pyr... 243 2e-61
D4AM06_ARTBC (tr|D4AM06) Putative uncharacterized protein OS=Art... 243 2e-61
F0UU14_AJEC8 (tr|F0UU14) Vacuolar membrane protein OS=Ajellomyce... 243 2e-61
F2S6K3_TRIT1 (tr|F2S6K3) Patched sphingolipid transporter OS=Tri... 242 3e-61
C7Z5H5_NECH7 (tr|C7Z5H5) Predicted protein OS=Nectria haematococ... 242 3e-61
R7Z255_9EURO (tr|R7Z255) Uncharacterized protein OS=Coniosporium... 242 4e-61
D4DB90_TRIVH (tr|D4DB90) Putative uncharacterized protein OS=Tri... 241 4e-61
F2SLM3_TRIRC (tr|F2SLM3) Patched sphingolipid transporter OS=Tri... 241 4e-61
M7TD76_9PEZI (tr|M7TD76) Putative patched sphingolipid transport... 241 5e-61
J3P1Z6_GAGT3 (tr|J3P1Z6) Niemann-Pick C1 protein OS=Gaeumannomyc... 241 7e-61
C0NRZ7_AJECG (tr|C0NRZ7) Putative uncharacterized protein OS=Aje... 241 8e-61
B2APT9_PODAN (tr|B2APT9) Podospora anserina S mat+ genomic DNA c... 241 8e-61
F7VMS2_SORMK (tr|F7VMS2) WGS project CABT00000000 data, contig 2... 240 1e-60
C1GRY4_PARBA (tr|C1GRY4) Patched sphingolipid transporter (Ncr1)... 238 6e-60
E4ZXV1_LEPMJ (tr|E4ZXV1) Similar to patched sphingolipid transpo... 237 8e-60
C5GGT7_AJEDR (tr|C5GGT7) Patched sphingolipid transporter OS=Aje... 237 1e-59
C5JHY3_AJEDS (tr|C5JHY3) Patched sphingolipid transporter OS=Aje... 237 1e-59
F2T222_AJEDA (tr|F2T222) Patched sphingolipid transporter OS=Aje... 237 1e-59
M1VVZ0_CLAPU (tr|M1VVZ0) Related to human PTC protein involved i... 237 1e-59
J9MSV5_FUSO4 (tr|J9MSV5) Uncharacterized protein OS=Fusarium oxy... 236 3e-59
N1Q8U7_9PEZI (tr|N1Q8U7) Uncharacterized protein OS=Pseudocercos... 235 3e-59
G1XTC9_ARTOA (tr|G1XTC9) Uncharacterized protein OS=Arthrobotrys... 235 4e-59
F9X956_MYCGM (tr|F9X956) NCR1, Niemann-pick type C OS=Mycosphaer... 234 5e-59
F9FNX7_FUSOF (tr|F9FNX7) Uncharacterized protein OS=Fusarium oxy... 234 7e-59
N4U1F7_FUSOX (tr|N4U1F7) Niemann-Pick type C-related protein 1 O... 234 7e-59
K3VY67_FUSPC (tr|K3VY67) Uncharacterized protein OS=Fusarium pse... 234 8e-59
R1GF75_9PEZI (tr|R1GF75) Putative patched sphingolipid transport... 234 1e-58
G7XA76_ASPKW (tr|G7XA76) Patched sphingolipid transporter OS=Asp... 233 1e-58
K9FXB4_PEND1 (tr|K9FXB4) Uncharacterized protein OS=Penicillium ... 233 2e-58
K9FV60_PEND2 (tr|K9FV60) Uncharacterized protein OS=Penicillium ... 233 2e-58
I1RY25_GIBZE (tr|I1RY25) Uncharacterized protein OS=Gibberella z... 233 2e-58
Q0CK25_ASPTN (tr|Q0CK25) Putative uncharacterized protein OS=Asp... 233 2e-58
N4XGI6_COCHE (tr|N4XGI6) Uncharacterized protein OS=Bipolaris ma... 233 2e-58
M2UL16_COCHE (tr|M2UL16) Uncharacterized protein OS=Bipolaris ma... 233 2e-58
F0X9U6_GROCL (tr|F0X9U6) Patched sphingolipid transporter OS=Gro... 232 4e-58
H1VM94_COLHI (tr|H1VM94) Patched sphingolipid transporter OS=Col... 231 5e-58
A1CTG5_ASPCL (tr|A1CTG5) Patched sphingolipid transporter (Ncr1)... 231 6e-58
M2NKG5_9PEZI (tr|M2NKG5) Uncharacterized protein OS=Baudoinia co... 231 8e-58
E3QUA2_COLGM (tr|E3QUA2) Patched sphingolipid transporter OS=Col... 230 1e-57
N4VGD5_COLOR (tr|N4VGD5) Patched sphingolipid transporter OS=Col... 230 1e-57
B8NIY3_ASPFN (tr|B8NIY3) Patched sphingolipid transporter (Ncr1)... 229 2e-57
I8IGC5_ASPO3 (tr|I8IGC5) Cholesterol transport protein OS=Asperg... 229 3e-57
C5MCB4_CANTT (tr|C5MCB4) Putative uncharacterized protein OS=Can... 228 4e-57
N1QMD0_9PEZI (tr|N1QMD0) Multidrug efflux transporter AcrB trans... 228 4e-57
K9HLF6_AGABB (tr|K9HLF6) Uncharacterized protein OS=Agaricus bis... 228 7e-57
Q59ZV0_CANAL (tr|Q59ZV0) Potential sterol homeostasis protein OS... 228 7e-57
C4YFP8_CANAW (tr|C4YFP8) Putative uncharacterized protein OS=Can... 227 8e-57
G8YM48_PICSO (tr|G8YM48) Piso0_001949 protein OS=Pichia sorbitop... 226 2e-56
M2T643_COCSA (tr|M2T643) Uncharacterized protein OS=Bipolaris so... 225 4e-56
K5XB43_AGABU (tr|K5XB43) Uncharacterized protein OS=Agaricus bis... 224 5e-56
K2S489_MACPH (tr|K2S489) Uncharacterized protein OS=Macrophomina... 224 7e-56
K1QD13_CRAGI (tr|K1QD13) Niemann-Pick C1 protein OS=Crassostrea ... 224 1e-55
K7TVT2_MAIZE (tr|K7TVT2) Uncharacterized protein OS=Zea mays GN=... 223 2e-55
H6CBA3_EXODN (tr|H6CBA3) Patched 1 OS=Exophiala dermatitidis (st... 222 3e-55
D8PKB4_SCHCM (tr|D8PKB4) Putative uncharacterized protein OS=Sch... 222 3e-55
N1Q2D3_MYCPJ (tr|N1Q2D3) Uncharacterized protein OS=Dothistroma ... 222 4e-55
E9E0K2_METAQ (tr|E9E0K2) Patched sphingolipid transporter OS=Met... 221 6e-55
G8YBA4_PICSO (tr|G8YBA4) Piso0_001949 protein OS=Pichia sorbitop... 221 7e-55
L8FXE1_GEOD2 (tr|L8FXE1) Uncharacterized protein OS=Geomyces des... 220 1e-54
E9ENZ2_METAR (tr|E9ENZ2) Patched sphingolipid transporter OS=Met... 219 2e-54
J4UQG8_BEAB2 (tr|J4UQG8) Patched sphingolipid transporter OS=Bea... 218 6e-54
F1QNG7_DANRE (tr|F1QNG7) Uncharacterized protein OS=Danio rerio ... 216 1e-53
N1JI99_ERYGR (tr|N1JI99) Niemann-Pick C1 protein OS=Blumeria gra... 216 3e-53
I3JSF2_ORENI (tr|I3JSF2) Uncharacterized protein OS=Oreochromis ... 215 5e-53
I3JSF3_ORENI (tr|I3JSF3) Uncharacterized protein OS=Oreochromis ... 214 9e-53
D5GC63_TUBMM (tr|D5GC63) Whole genome shotgun sequence assembly,... 212 3e-52
G2YSF6_BOTF4 (tr|G2YSF6) Similar to patched sphingolipid transpo... 212 4e-52
G1K8E5_ANOCA (tr|G1K8E5) Uncharacterized protein (Fragment) OS=A... 211 5e-52
Q7RWL9_NEUCR (tr|Q7RWL9) Putative uncharacterized protein OS=Neu... 211 6e-52
M7U3J8_BOTFU (tr|M7U3J8) Putative patched sphingolipid transport... 211 6e-52
H8X9T5_CANO9 (tr|H8X9T5) Ncr1 h OS=Candida orthopsilosis (strain... 211 8e-52
G8BL56_CANPC (tr|G8BL56) Putative uncharacterized protein OS=Can... 210 1e-51
M3HR68_CANMA (tr|M3HR68) Uncharacterized protein OS=Candida malt... 209 2e-51
F7CFS9_XENTR (tr|F7CFS9) Uncharacterized protein (Fragment) OS=X... 209 2e-51
J4G101_FIBRA (tr|J4G101) Uncharacterized protein OS=Fibroporia r... 209 2e-51
F6N6I8_DANRE (tr|F6N6I8) Niemann-Pick disease type C1 protein OS... 209 2e-51
H0XBD5_OTOGA (tr|H0XBD5) Uncharacterized protein OS=Otolemur gar... 209 2e-51
K1VIA0_TRIAC (tr|K1VIA0) Vacuolar membrane protein OS=Trichospor... 207 7e-51
G3PZ00_GASAC (tr|G3PZ00) Uncharacterized protein (Fragment) OS=G... 207 8e-51
Q9JLG3_CRIGR (tr|Q9JLG3) Niemann-Pick type C1 protein OS=Cricetu... 206 3e-50
G3J3M1_CORMM (tr|G3J3M1) Niemann-Pick C1 protein OS=Cordyceps mi... 205 3e-50
Q3U2B2_MOUSE (tr|Q3U2B2) Putative uncharacterized protein OS=Mus... 205 4e-50
Q7TMD4_MOUSE (tr|Q7TMD4) Niemann Pick type C1 OS=Mus musculus GN... 205 5e-50
L9JF67_TUPCH (tr|L9JF67) Niemann-Pick C1 protein OS=Tupaia chine... 204 6e-50
G3HT60_CRIGR (tr|G3HT60) Niemann-Pick C1 protein (Fragment) OS=C... 204 7e-50
L5K297_PTEAL (tr|L5K297) Niemann-Pick C1 protein OS=Pteropus ale... 204 8e-50
M3Y344_MUSPF (tr|M3Y344) Uncharacterized protein OS=Mustela puto... 203 1e-49
H3DBI8_TETNG (tr|H3DBI8) Uncharacterized protein (Fragment) OS=T... 203 2e-49
H2NW18_PONAB (tr|H2NW18) Uncharacterized protein OS=Pongo abelii... 203 2e-49
F1SBB5_PIG (tr|F1SBB5) Niemann-Pick C1 protein OS=Sus scrofa GN=... 203 2e-49
F6XL99_HORSE (tr|F6XL99) Uncharacterized protein OS=Equus caball... 202 2e-49
G3V7K5_RAT (tr|G3V7K5) Protein Npc1 OS=Rattus norvegicus GN=Npc1... 202 4e-49
A5DNY6_PICGU (tr|A5DNY6) Putative uncharacterized protein OS=Mey... 201 6e-49
G1P8K0_MYOLU (tr|G1P8K0) Uncharacterized protein (Fragment) OS=M... 201 7e-49
K1PF48_CRAGI (tr|K1PF48) Niemann-Pick C1 protein OS=Crassostrea ... 201 8e-49
M4APW1_XIPMA (tr|M4APW1) Uncharacterized protein OS=Xiphophorus ... 201 9e-49
E7RBT3_PICAD (tr|E7RBT3) Vacuolar membrane protein OS=Pichia ang... 199 2e-48
K5WIE2_PHACS (tr|K5WIE2) Uncharacterized protein OS=Phanerochaet... 199 2e-48
Q5KGS9_CRYNJ (tr|Q5KGS9) Vacuolar membrane protein, putative OS=... 199 2e-48
L8XAN1_9HOMO (tr|L8XAN1) Patched sphingolipid transporter (Ncr1)... 199 2e-48
Q4RWY5_TETNG (tr|Q4RWY5) Chromosome 15 SCAF14981, whole genome s... 199 2e-48
I2CU31_MACMU (tr|I2CU31) Niemann-Pick C1 protein OS=Macaca mulat... 199 2e-48
H9FUY5_MACMU (tr|H9FUY5) Niemann-Pick C1 protein OS=Macaca mulat... 199 2e-48
Q55SD4_CRYNB (tr|Q55SD4) Putative uncharacterized protein OS=Cry... 199 3e-48
G3TMS9_LOXAF (tr|G3TMS9) Uncharacterized protein OS=Loxodonta af... 199 3e-48
H2U260_TAKRU (tr|H2U260) Uncharacterized protein (Fragment) OS=T... 199 3e-48
Q59GR1_HUMAN (tr|Q59GR1) Niemann-Pick disease, type C1 variant (... 199 4e-48
D2GUU3_AILME (tr|D2GUU3) Putative uncharacterized protein (Fragm... 198 4e-48
Q6FKT2_CANGA (tr|Q6FKT2) Similar to uniprot|Q12200 Saccharomyces... 198 4e-48
G1M5K1_AILME (tr|G1M5K1) Uncharacterized protein (Fragment) OS=A... 198 5e-48
H3I2S2_STRPU (tr|H3I2S2) Uncharacterized protein OS=Strongylocen... 197 8e-48
G3QQY7_GORGO (tr|G3QQY7) Uncharacterized protein OS=Gorilla gori... 197 1e-47
G3SJE7_GORGO (tr|G3SJE7) Uncharacterized protein (Fragment) OS=G... 197 1e-47
H2MTM9_ORYLA (tr|H2MTM9) Uncharacterized protein (Fragment) OS=O... 197 1e-47
Q8MKD8_FELCA (tr|Q8MKD8) Niemann-Pick C1 OS=Felis catus PE=2 SV=1 197 1e-47
Q9N0Q0_FELCA (tr|Q9N0Q0) Niemann-Pick type C1 disease protein OS... 196 2e-47
Q8MI49_FELCA (tr|Q8MI49) Mutant Niemann-Pick C1 OS=Felis catus P... 196 2e-47
R0KEG6_ANAPL (tr|R0KEG6) Niemann-Pick C1 protein (Fragment) OS=A... 196 2e-47
G1NCL6_MELGA (tr|G1NCL6) Uncharacterized protein (Fragment) OS=M... 196 3e-47
H0ZJN3_TAEGU (tr|H0ZJN3) Uncharacterized protein OS=Taeniopygia ... 196 3e-47
F1NQT4_CHICK (tr|F1NQT4) Uncharacterized protein (Fragment) OS=G... 195 3e-47
M3VUX6_FELCA (tr|M3VUX6) Uncharacterized protein OS=Felis catus ... 195 4e-47
H2QEC5_PANTR (tr|H2QEC5) Uncharacterized protein OS=Pan troglody... 195 4e-47
K7BF17_PANTR (tr|K7BF17) Niemann-Pick disease, type C1 OS=Pan tr... 195 4e-47
F7DIC2_MACMU (tr|F7DIC2) Uncharacterized protein (Fragment) OS=M... 193 1e-46
Q6BT03_DEBHA (tr|Q6BT03) DEHA2D04620p OS=Debaryomyces hansenii (... 193 2e-46
K7FH26_PELSI (tr|K7FH26) Uncharacterized protein (Fragment) OS=P... 192 2e-46
K7DIM3_PANTR (tr|K7DIM3) Niemann-Pick disease, type C1 OS=Pan tr... 192 3e-46
F2QMI3_PICP7 (tr|F2QMI3) Niemann-Pick C1 protein OS=Komagataella... 192 5e-46
C4QWB0_PICPG (tr|C4QWB0) Vacuolar membrane protein that transits... 192 5e-46
L8IF09_BOSMU (tr|L8IF09) Niemann-Pick C1 protein (Fragment) OS=B... 191 5e-46
B0JYK2_BOVIN (tr|B0JYK2) NPC1 protein OS=Bos taurus GN=NPC1 PE=2... 191 9e-46
J9VSE9_CRYNH (tr|J9VSE9) Vacuolar membrane protein OS=Cryptococc... 191 1e-45
H0V7B5_CAVPO (tr|H0V7B5) Uncharacterized protein (Fragment) OS=C... 191 1e-45
Q2U2G2_ASPOR (tr|Q2U2G2) Cholesterol transport protein OS=Asperg... 190 1e-45
H3BC01_LATCH (tr|H3BC01) Uncharacterized protein (Fragment) OS=L... 190 2e-45
H3BC00_LATCH (tr|H3BC00) Uncharacterized protein OS=Latimeria ch... 189 2e-45
F7INK8_CALJA (tr|F7INK8) Uncharacterized protein (Fragment) OS=C... 189 3e-45
K0KA28_WICCF (tr|K0KA28) Niemann-Pick type C-related protein 1 O... 187 1e-44
Q9GLC9_BOVIN (tr|Q9GLC9) Niemann-Pick type C1 disease protein OS... 187 1e-44
Q6CIF2_KLULA (tr|Q6CIF2) KLLA0F27137p OS=Kluyveromyces lactis (s... 184 6e-44
R4XFW5_9ASCO (tr|R4XFW5) Putative Patched sphingolipid transport... 182 5e-43
C5DXD6_ZYGRC (tr|C5DXD6) ZYRO0F04180p OS=Zygosaccharomyces rouxi... 181 5e-43
A7S0G1_NEMVE (tr|A7S0G1) Predicted protein (Fragment) OS=Nematos... 180 2e-42
A5BZU0_VITVI (tr|A5BZU0) Putative uncharacterized protein OS=Vit... 179 2e-42
F1KQH8_ASCSU (tr|F1KQH8) Niemann-Pick C1 protein OS=Ascaris suum... 179 3e-42
F1KQ97_ASCSU (tr|F1KQ97) Niemann-Pick C1 protein OS=Ascaris suum... 179 3e-42
B4HWH4_DROSE (tr|B4HWH4) GM11941 OS=Drosophila sechellia GN=Dsec... 179 4e-42
F7INM5_CALJA (tr|F7INM5) Uncharacterized protein OS=Callithrix j... 179 4e-42
B3MPM8_DROAN (tr|B3MPM8) GF14130 OS=Drosophila ananassae GN=Dana... 178 4e-42
C7GV50_YEAS2 (tr|C7GV50) Ncr1p OS=Saccharomyces cerevisiae (stra... 178 6e-42
H3ITD6_STRPU (tr|H3ITD6) Uncharacterized protein OS=Strongylocen... 178 7e-42
G2WPH4_YEASK (tr|G2WPH4) K7_Ncr1p OS=Saccharomyces cerevisiae (s... 177 1e-41
H0GPT2_9SACH (tr|H0GPT2) Ncr1p OS=Saccharomyces cerevisiae x Sac... 177 1e-41
A6ZWP0_YEAS7 (tr|A6ZWP0) Niemann-Pick type C-related protein OS=... 177 1e-41
C8ZJ20_YEAS8 (tr|C8ZJ20) Ncr1p OS=Saccharomyces cerevisiae (stra... 177 1e-41
N1NVZ9_YEASX (tr|N1NVZ9) Ncr1p OS=Saccharomyces cerevisiae CEN.P... 177 1e-41
B3LL56_YEAS1 (tr|B3LL56) Transmembrane protein OS=Saccharomyces ... 177 1e-41
H0XHF3_OTOGA (tr|H0XHF3) Uncharacterized protein OS=Otolemur gar... 175 4e-41
G8ZR59_TORDC (tr|G8ZR59) Uncharacterized protein OS=Torulaspora ... 175 5e-41
B7ZLE6_HUMAN (tr|B7ZLE6) NPC1L1 protein OS=Homo sapiens GN=NPC1L... 174 8e-41
C5DBG1_LACTC (tr|C5DBG1) KLTH0A02332p OS=Lachancea thermotoleran... 174 1e-40
Q9VL24_DROME (tr|Q9VL24) Niemann-Pick type C-1a, isoform A OS=Dr... 173 1e-40
J8Q0Y3_SACAR (tr|J8Q0Y3) Ncr1p OS=Saccharomyces arboricola (stra... 173 1e-40
Q7YU59_DROME (tr|Q7YU59) RE56428p OS=Drosophila melanogaster GN=... 173 1e-40
Q9U5W1_DROME (tr|Q9U5W1) NPC1 protein OS=Drosophila melanogaster... 173 1e-40
G3S497_GORGO (tr|G3S497) Uncharacterized protein OS=Gorilla gori... 173 2e-40
H0H292_9SACH (tr|H0H292) Ncr1p OS=Saccharomyces cerevisiae x Sac... 172 2e-40
G1QUH0_NOMLE (tr|G1QUH0) Uncharacterized protein OS=Nomascus leu... 172 2e-40
B4Q8Q7_DROSI (tr|B4Q8Q7) GD22294 OS=Drosophila simulans GN=Dsim\... 172 3e-40
K7FGY8_PELSI (tr|K7FGY8) Uncharacterized protein OS=Pelodiscus s... 172 3e-40
H2R5C0_PANTR (tr|H2R5C0) Uncharacterized protein OS=Pan troglody... 172 4e-40
G3WDA4_SARHA (tr|G3WDA4) Uncharacterized protein (Fragment) OS=S... 172 4e-40
J7S5U3_KAZNA (tr|J7S5U3) Uncharacterized protein OS=Kazachstania... 171 5e-40
E0VVZ7_PEDHC (tr|E0VVZ7) Niemann-Pick C1 protein, putative OS=Pe... 168 6e-39
F6U2U0_MACMU (tr|F6U2U0) Uncharacterized protein OS=Macaca mulat... 168 7e-39
E2C5L5_HARSA (tr|E2C5L5) Niemann-Pick C1 protein OS=Harpegnathos... 167 9e-39
A0MJA6_MACFA (tr|A0MJA6) Niemann-Pick C1-like 1 protein OS=Macac... 167 9e-39
A0MJA5_MACMU (tr|A0MJA5) Niemann-Pick C1-like 1 protein OS=Macac... 167 9e-39
F6RBH5_MACMU (tr|F6RBH5) Uncharacterized protein OS=Macaca mulat... 167 9e-39
G7MLD6_MACMU (tr|G7MLD6) Niemann-Pick C1-like protein 1 OS=Macac... 167 1e-38
D8UCK6_VOLCA (tr|D8UCK6) Oxygen-evolving enhancer protein 2 OS=V... 167 1e-38
G7P295_MACFA (tr|G7P295) Niemann-Pick C1-like protein 1 OS=Macac... 166 2e-38
B4JPL7_DROGR (tr|B4JPL7) GH13378 OS=Drosophila grimshawi GN=Dgri... 164 9e-38
G5BIK8_HETGA (tr|G5BIK8) Niemann-Pick C1-like protein 1 OS=Heter... 164 1e-37
G8C221_TETPH (tr|G8C221) Uncharacterized protein OS=Tetrapisispo... 163 2e-37
M3WCY7_FELCA (tr|M3WCY7) Uncharacterized protein OS=Felis catus ... 163 2e-37
H2PM80_PONAB (tr|H2PM80) Uncharacterized protein OS=Pongo abelii... 162 2e-37
A8NWN7_COPC7 (tr|A8NWN7) Vacuolar membrane protein OS=Coprinopsi... 160 1e-36
F1QZW8_DANRE (tr|F1QZW8) Uncharacterized protein (Fragment) OS=D... 160 1e-36
B4NZ62_DROYA (tr|B4NZ62) GE26328 OS=Drosophila yakuba GN=Dyak\GE... 160 2e-36
G3WVB8_SARHA (tr|G3WVB8) Uncharacterized protein OS=Sarcophilus ... 158 6e-36
I2H436_TETBL (tr|I2H436) Uncharacterized protein OS=Tetrapisispo... 158 6e-36
M3XGJ9_LATCH (tr|M3XGJ9) Uncharacterized protein OS=Latimeria ch... 155 3e-35
E1BPS5_BOVIN (tr|E1BPS5) Uncharacterized protein OS=Bos taurus G... 155 3e-35
G3HMB0_CRIGR (tr|G3HMB0) Niemann-Pick C1-like protein 1 OS=Crice... 155 4e-35
H2Z2C5_CIOSA (tr|H2Z2C5) Uncharacterized protein (Fragment) OS=C... 154 7e-35
E1Z5G4_CHLVA (tr|E1Z5G4) Putative uncharacterized protein (Fragm... 154 8e-35
H0VFJ6_CAVPO (tr|H0VFJ6) Uncharacterized protein OS=Cavia porcel... 154 1e-34
I3MT02_SPETR (tr|I3MT02) Uncharacterized protein (Fragment) OS=S... 152 5e-34
M3Z3C3_MUSPF (tr|M3Z3C3) Uncharacterized protein OS=Mustela puto... 152 5e-34
L8YA02_TUPCH (tr|L8YA02) Niemann-Pick C1-like protein 1 OS=Tupai... 151 6e-34
A0MJA8_MESAU (tr|A0MJA8) Niemann-Pick C1-like 1 protein OS=Mesoc... 151 7e-34
G7NKH2_MACMU (tr|G7NKH2) Niemann-Pick C1 protein OS=Macaca mulat... 147 2e-32
G2QX16_THITE (tr|G2QX16) Putative uncharacterized protein OS=Thi... 146 2e-32
M4GG07_MAGP6 (tr|M4GG07) Uncharacterized protein OS=Magnaporthe ... 146 2e-32
H2AQ20_KAZAF (tr|H2AQ20) Uncharacterized protein OS=Kazachstania... 145 4e-32
Q0U4X8_PHANO (tr|Q0U4X8) Putative uncharacterized protein OS=Pha... 144 9e-32
C4JHE8_UNCRE (tr|C4JHE8) Putative uncharacterized protein OS=Unc... 144 1e-31
B6QA78_PENMQ (tr|B6QA78) Patched sphingolipid transporter (Ncr1)... 143 2e-31
B8M187_TALSN (tr|B8M187) Patched sphingolipid transporter (Ncr1)... 142 4e-31
C3ZSN0_BRAFL (tr|C3ZSN0) Putative uncharacterized protein OS=Bra... 142 5e-31
F6YGU8_CIOIN (tr|F6YGU8) Uncharacterized protein (Fragment) OS=C... 141 6e-31
G3AP57_SPAPN (tr|G3AP57) Putative uncharacterized protein OS=Spa... 141 8e-31
I1BHC9_RHIO9 (tr|I1BHC9) Uncharacterized protein OS=Rhizopus del... 140 2e-30
G2X5E0_VERDV (tr|G2X5E0) Niemann-Pick C1 protein OS=Verticillium... 139 2e-30
G3B7N2_CANTC (tr|G3B7N2) Putative uncharacterized protein OS=Can... 139 3e-30
E4V4C8_ARTGP (tr|E4V4C8) Niemann-Pick C1 protein OS=Arthroderma ... 139 4e-30
L2FHI3_COLGN (tr|L2FHI3) Patched sphingolipid transporter OS=Col... 138 5e-30
G3YCX9_ASPNA (tr|G3YCX9) Putative uncharacterized protein OS=Asp... 138 5e-30
A2QWF9_ASPNC (tr|A2QWF9) Remark: Niemann-Pick C (Precursor) OS=A... 138 6e-30
K7J472_NASVI (tr|K7J472) Uncharacterized protein OS=Nasonia vitr... 137 1e-29
A1DN50_NEOFI (tr|A1DN50) Patched sphingolipid transporter (Ncr1)... 137 1e-29
A5E1Z8_LODEL (tr|A5E1Z8) Putative uncharacterized protein OS=Lod... 137 2e-29
F6X4B2_HORSE (tr|F6X4B2) Uncharacterized protein OS=Equus caball... 136 2e-29
Q2GRY0_CHAGB (tr|Q2GRY0) Putative uncharacterized protein OS=Cha... 135 4e-29
D3B0C2_POLPA (tr|D3B0C2) Niemann-Pick C type protein OS=Polyspho... 135 5e-29
I1G5E9_AMPQE (tr|I1G5E9) Uncharacterized protein OS=Amphimedon q... 134 9e-29
M7BRM6_CHEMY (tr|M7BRM6) Niemann-Pick C1 protein OS=Chelonia myd... 134 1e-28
F4WWI9_ACREC (tr|F4WWI9) Niemann-Pick C1 protein OS=Acromyrmex e... 134 1e-28
Q9TT75_RABIT (tr|Q9TT75) Niemann-Pick type C1 disease protein OS... 134 1e-28
F7FVQ9_ORNAN (tr|F7FVQ9) Uncharacterized protein (Fragment) OS=O... 134 1e-28
G1SY19_RABIT (tr|G1SY19) Uncharacterized protein (Fragment) OS=O... 134 2e-28
G1R4S7_NOMLE (tr|G1R4S7) Uncharacterized protein OS=Nomascus leu... 133 2e-28
F7G2R7_MONDO (tr|F7G2R7) Uncharacterized protein OS=Monodelphis ... 133 2e-28
F1PB50_CANFA (tr|F1PB50) Uncharacterized protein (Fragment) OS=C... 132 3e-28
G3UGY4_LOXAF (tr|G3UGY4) Uncharacterized protein (Fragment) OS=L... 132 3e-28
Q9GK52_CANFA (tr|Q9GK52) Niemann-Pick type C1 disease protein OS... 132 3e-28
G7PWI5_MACFA (tr|G7PWI5) Niemann-Pick C1 protein OS=Macaca fasci... 132 3e-28
I3M891_SPETR (tr|I3M891) Uncharacterized protein (Fragment) OS=S... 132 5e-28
R7TF67_9ANNE (tr|R7TF67) Uncharacterized protein OS=Capitella te... 131 8e-28
F8PNI3_SERL3 (tr|F8PNI3) Putative uncharacterized protein OS=Ser... 130 1e-27
A3GGU6_PICST (tr|A3GGU6) Uncharacterized protein OS=Scheffersomy... 130 1e-27
F8NMA2_SERL9 (tr|F8NMA2) Putative uncharacterized protein OS=Ser... 130 1e-27
L7LZ50_9ACAR (tr|L7LZ50) Putative cholesterol transport protein ... 130 1e-27
Q750G1_ASHGO (tr|Q750G1) AGL008Wp OS=Ashbya gossypii (strain ATC... 130 1e-27
M9N5A8_ASHGS (tr|M9N5A8) FAGL008Wp OS=Ashbya gossypii FDAG1 GN=F... 130 1e-27
B4DIP7_HUMAN (tr|B4DIP7) cDNA FLJ57114, highly similar to Nieman... 130 1e-27
B9WA46_CANDC (tr|B9WA46) Sterol homeostasis regulator, putative ... 130 1e-27
F4RFI3_MELLP (tr|F4RFI3) Putative uncharacterized protein OS=Mel... 130 2e-27
H2Z3C5_CIOSA (tr|H2Z3C5) Uncharacterized protein OS=Ciona savign... 129 2e-27
H2Z3C9_CIOSA (tr|H2Z3C9) Uncharacterized protein OS=Ciona savign... 129 2e-27
H2Z3D0_CIOSA (tr|H2Z3D0) Uncharacterized protein OS=Ciona savign... 129 2e-27
H2Z3C7_CIOSA (tr|H2Z3C7) Uncharacterized protein OS=Ciona savign... 129 3e-27
H2Z3C6_CIOSA (tr|H2Z3C6) Uncharacterized protein OS=Ciona savign... 129 3e-27
G7YQQ4_CLOSI (tr|G7YQQ4) Niemann-Pick C1 protein OS=Clonorchis s... 129 3e-27
H9HR60_ATTCE (tr|H9HR60) Uncharacterized protein OS=Atta cephalo... 129 3e-27
A7EA90_SCLS1 (tr|A7EA90) Putative uncharacterized protein OS=Scl... 129 3e-27
B0CUV0_LACBS (tr|B0CUV0) Predicted protein OS=Laccaria bicolor (... 129 3e-27
R7T1Z0_DICSQ (tr|R7T1Z0) Multidrug efflux transporter AcrB trans... 129 3e-27
H2Z3D1_CIOSA (tr|H2Z3D1) Uncharacterized protein (Fragment) OS=C... 129 3e-27
E3KVQ7_PUCGT (tr|E3KVQ7) Putative uncharacterized protein OS=Puc... 128 7e-27
G4TPT7_PIRID (tr|G4TPT7) Related to NCR1-transmembrane glycoprot... 128 7e-27
A6RA01_AJECN (tr|A6RA01) Putative uncharacterized protein OS=Aje... 127 9e-27
F7I3S7_CALJA (tr|F7I3S7) Uncharacterized protein OS=Callithrix j... 127 1e-26
C6HD90_AJECH (tr|C6HD90) Patched sphingolipid transporter OS=Aje... 127 1e-26
M5FUW2_DACSP (tr|M5FUW2) Multidrug efflux transporter AcrB trans... 127 1e-26
G5BTQ9_HETGA (tr|G5BTQ9) Niemann-Pick C1 protein OS=Heterocephal... 126 3e-26
B3S409_TRIAD (tr|B3S409) Putative uncharacterized protein (Fragm... 125 4e-26
B4M8H0_DROVI (tr|B4M8H0) GJ18108 OS=Drosophila virilis GN=Dvir\G... 124 1e-25
H2Z3C8_CIOSA (tr|H2Z3C8) Uncharacterized protein OS=Ciona savign... 124 1e-25
M2QUR9_CERSU (tr|M2QUR9) Uncharacterized protein OS=Ceriporiopsi... 124 1e-25
G6DLG9_DANPL (tr|G6DLG9) Uncharacterized protein OS=Danaus plexi... 124 1e-25
B0WCU9_CULQU (tr|B0WCU9) Niemann-pick C1 OS=Culex quinquefasciat... 124 1e-25
C4Y974_CLAL4 (tr|C4Y974) Putative uncharacterized protein OS=Cla... 123 2e-25
K1WBJ5_MARBU (tr|K1WBJ5) Patched sphingolipid transporter OS=Mar... 122 5e-25
E6R703_CRYGW (tr|E6R703) Vacuolar membrane protein, putative OS=... 122 5e-25
Q17FP9_AEDAE (tr|Q17FP9) AAEL003325-PA (Fragment) OS=Aedes aegyp... 122 5e-25
N6TS49_9CUCU (tr|N6TS49) Uncharacterized protein (Fragment) OS=D... 121 7e-25
B7PPF5_IXOSC (tr|B7PPF5) Niemann-Pick type C1 domain-containing ... 121 7e-25
F1A064_DICPU (tr|F1A064) Putative uncharacterized protein OS=Dic... 121 1e-24
F1KTP5_ASCSU (tr|F1KTP5) Niemann-Pick C1 protein OS=Ascaris suum... 120 1e-24
H0EKT5_GLAL7 (tr|H0EKT5) Putative Niemann-Pick type C-related pr... 120 2e-24
Q9TVK6_DICDI (tr|Q9TVK6) NPC1 protein OS=Dictyostelium discoideu... 120 2e-24
F7D6Z0_MONDO (tr|F7D6Z0) Uncharacterized protein OS=Monodelphis ... 120 2e-24
F6VD72_XENTR (tr|F6VD72) Uncharacterized protein OS=Xenopus trop... 120 2e-24
G0W920_NAUDC (tr|G0W920) Uncharacterized protein OS=Naumovozyma ... 120 2e-24
H9KK92_APIME (tr|H9KK92) Uncharacterized protein OS=Apis mellife... 120 2e-24
E3LEG6_CAERE (tr|E3LEG6) CRE-NCR-1 protein OS=Caenorhabditis rem... 119 3e-24
F0ZM98_DICPU (tr|F0ZM98) Putative uncharacterized protein OS=Dic... 119 4e-24
E9J1S5_SOLIN (tr|E9J1S5) Putative uncharacterized protein (Fragm... 119 4e-24
M7WML9_RHOTO (tr|M7WML9) Vacuolar membrane protein OS=Rhodospori... 119 4e-24
E5S331_TRISP (tr|E5S331) Niemann-Pick C1 protein OS=Trichinella ... 119 4e-24
Q7Q409_ANOGA (tr|Q7Q409) AGAP008137-PA OS=Anopheles gambiae GN=A... 118 5e-24
H2Z2C6_CIOSA (tr|H2Z2C6) Uncharacterized protein (Fragment) OS=C... 118 7e-24
D2CG00_TRICA (tr|D2CG00) Putative uncharacterized protein GLEAN_... 117 1e-23
F7HZ08_CALJA (tr|F7HZ08) Uncharacterized protein (Fragment) OS=C... 117 1e-23
H9JHQ1_BOMMO (tr|H9JHQ1) Uncharacterized protein OS=Bombyx mori ... 116 2e-23
I3JXJ4_ORENI (tr|I3JXJ4) Uncharacterized protein (Fragment) OS=O... 116 2e-23
I3JXJ3_ORENI (tr|I3JXJ3) Uncharacterized protein OS=Oreochromis ... 116 3e-23
E3WTF1_ANODA (tr|E3WTF1) Uncharacterized protein OS=Anopheles da... 116 3e-23
A8XK09_CAEBR (tr|A8XK09) Protein CBR-NCR-1 OS=Caenorhabditis bri... 114 8e-23
B4KJH6_DROMO (tr|B4KJH6) GI18274 (Fragment) OS=Drosophila mojave... 114 9e-23
M4ALM9_XIPMA (tr|M4ALM9) Uncharacterized protein (Fragment) OS=X... 114 1e-22
Q16VL3_AEDAE (tr|Q16VL3) AAEL009531-PA OS=Aedes aegypti GN=AAEL0... 114 1e-22
M9LSA9_9BASI (tr|M9LSA9) Cholesterol transport protein OS=Pseudo... 114 1e-22
A8PPM4_BRUMA (tr|A8PPM4) Niemann-Pick C1 protein, putative OS=Br... 114 1e-22
D3AZN2_POLPA (tr|D3AZN2) Uncharacterized protein OS=Polysphondyl... 113 2e-22
G8JWD9_ERECY (tr|G8JWD9) Uncharacterized protein OS=Eremothecium... 113 3e-22
G0M845_CAEBE (tr|G0M845) CBN-NCR-1 protein OS=Caenorhabditis bre... 113 3e-22
E4YAC7_OIKDI (tr|E4YAC7) Whole genome shotgun assembly, allelic ... 112 4e-22
E4X840_OIKDI (tr|E4X840) Whole genome shotgun assembly, referenc... 112 5e-22
H9I3S0_ATTCE (tr|H9I3S0) Uncharacterized protein OS=Atta cephalo... 112 5e-22
F4WKN5_ACREC (tr|F4WKN5) Niemann-Pick C1 protein (Fragment) OS=A... 111 9e-22
A0MJA7_RABIT (tr|A0MJA7) Niemann-Pick C1-like 1 protein OS=Oryct... 111 1e-21
D2VWP3_NAEGR (tr|D2VWP3) Predicted protein OS=Naegleria gruberi ... 110 1e-21
L7LVE4_9ACAR (tr|L7LVE4) Putative niemann-pick c1 protein OS=Rhi... 110 2e-21
L7M730_9ACAR (tr|L7M730) Putative niemann-pick c1 protein OS=Rhi... 109 2e-21
I2G2W6_USTH4 (tr|I2G2W6) Related to NCR1-transmembrane glycoprot... 109 3e-21
F6RCK1_CIOIN (tr|F6RCK1) Uncharacterized protein (Fragment) OS=C... 109 3e-21
G3TKB2_LOXAF (tr|G3TKB2) Uncharacterized protein OS=Loxodonta af... 109 3e-21
E9HE42_DAPPU (tr|E9HE42) Putative uncharacterized protein OS=Dap... 108 4e-21
G7DSL0_MIXOS (tr|G7DSL0) Uncharacterized protein OS=Mixia osmund... 108 5e-21
N6UEG8_9CUCU (tr|N6UEG8) Uncharacterized protein (Fragment) OS=D... 108 5e-21
N6UHN8_9CUCU (tr|N6UHN8) Uncharacterized protein (Fragment) OS=D... 108 6e-21
B4L379_DROMO (tr|B4L379) GI15499 OS=Drosophila mojavensis GN=Dmo... 107 9e-21
B7Q350_IXOSC (tr|B7Q350) Niemann-Pick type C1 domain-containing ... 107 1e-20
H2MC24_ORYLA (tr|H2MC24) Uncharacterized protein OS=Oryzias lati... 107 1e-20
J3PX61_PUCT1 (tr|J3PX61) Uncharacterized protein OS=Puccinia tri... 107 1e-20
L5KNZ8_PTEAL (tr|L5KNZ8) Niemann-Pick C1-like protein 1 OS=Ptero... 107 1e-20
E9GUJ6_DAPPU (tr|E9GUJ6) Putative uncharacterized protein OS=Dap... 107 2e-20
J0M640_LOALO (tr|J0M640) Niemann-Pick C1 protein OS=Loa loa GN=L... 106 2e-20
G6DF67_DANPL (tr|G6DF67) Uncharacterized protein OS=Danaus plexi... 106 2e-20
Q6CBA1_YARLI (tr|Q6CBA1) YALI0C20757p OS=Yarrowia lipolytica (st... 106 2e-20
G3PDG6_GASAC (tr|G3PDG6) Uncharacterized protein (Fragment) OS=G... 105 4e-20
H2Z2C2_CIOSA (tr|H2Z2C2) Uncharacterized protein (Fragment) OS=C... 105 4e-20
J5Q2P2_TRIAS (tr|J5Q2P2) Uncharacterized protein OS=Trichosporon... 105 4e-20
E2LGP8_MONPE (tr|E2LGP8) Uncharacterized protein (Fragment) OS=M... 105 5e-20
G1MH71_AILME (tr|G1MH71) Uncharacterized protein OS=Ailuropoda m... 104 8e-20
D2HNN8_AILME (tr|D2HNN8) Putative uncharacterized protein (Fragm... 104 8e-20
R0KZY9_ANAPL (tr|R0KZY9) Niemann-Pick C1-like protein 1 OS=Anas ... 104 8e-20
H2SIS0_TAKRU (tr|H2SIS0) Uncharacterized protein OS=Takifugu rub... 104 9e-20
H2Z2C1_CIOSA (tr|H2Z2C1) Uncharacterized protein OS=Ciona savign... 104 1e-19
R9P4P3_9BASI (tr|R9P4P3) Uncharacterized protein OS=Pseudozyma h... 103 1e-19
A0MJA4_CANFA (tr|A0MJA4) Niemann-Pick C1-like 1 protein OS=Canis... 103 2e-19
H2Z2C3_CIOSA (tr|H2Z2C3) Uncharacterized protein (Fragment) OS=C... 103 2e-19
A3KMG9_MOUSE (tr|A3KMG9) Npc1l1 protein (Fragment) OS=Mus muscul... 103 2e-19
A2RRR0_MOUSE (tr|A2RRR0) Npc1l1 protein OS=Mus musculus GN=Npc1l... 103 2e-19
D6WXX5_TRICA (tr|D6WXX5) Putative uncharacterized protein OS=Tri... 103 2e-19
Q7PS03_ANOGA (tr|Q7PS03) AGAP000579-PA OS=Anopheles gambiae GN=A... 103 2e-19
E6ZX42_SPORE (tr|E6ZX42) Related to NCR1-transmembrane glycoprot... 103 3e-19
Q551C5_DICDI (tr|Q551C5) Putative uncharacterized protein OS=Dic... 102 3e-19
F0X097_9STRA (tr|F0X097) ResistanceNodulationCell Division (RND)... 102 5e-19
E2C7P2_HARSA (tr|E2C7P2) Niemann-Pick C1 protein OS=Harpegnathos... 102 5e-19
B3N938_DROER (tr|B3N938) GG23970 OS=Drosophila erecta GN=Dere\GG... 102 5e-19
F4PR05_DICFS (tr|F4PR05) Niemann-Pick C type protein OS=Dictyost... 102 6e-19
H9KCD8_APIME (tr|H9KCD8) Uncharacterized protein OS=Apis mellife... 101 8e-19
E2AJ59_CAMFO (tr|E2AJ59) Niemann-Pick C1 protein OS=Camponotus f... 101 9e-19
H3H542_PHYRM (tr|H3H542) Uncharacterized protein OS=Phytophthora... 100 1e-18
Q4PE83_USTMA (tr|Q4PE83) Putative uncharacterized protein OS=Ust... 100 1e-18
H2SIR9_TAKRU (tr|H2SIR9) Uncharacterized protein (Fragment) OS=T... 100 2e-18
M5BJY2_9HOMO (tr|M5BJY2) Niemann-Pick type C-related protein 1 O... 100 2e-18
F4PV61_DICFS (tr|F4PV61) Niemann-Pick C type protein OS=Dictyost... 100 2e-18
B3NY50_DROER (tr|B3NY50) GG19701 OS=Drosophila erecta GN=Dere\GG... 99 4e-18
L1K3A1_GUITH (tr|L1K3A1) Uncharacterized protein OS=Guillardia t... 99 5e-18
B4MSW0_DROWI (tr|B4MSW0) GK19822 OS=Drosophila willistoni GN=Dwi... 98 8e-18
B4JXM3_DROGR (tr|B4JXM3) GH17745 OS=Drosophila grimshawi GN=Dgri... 98 8e-18
Q9VRC9_DROME (tr|Q9VRC9) Niemann-Pick type C-1b OS=Drosophila me... 98 1e-17
A7TTL1_VANPO (tr|A7TTL1) Putative uncharacterized protein OS=Van... 98 1e-17
E0W1Y7_PEDHC (tr|E0W1Y7) Niemann-Pick C1 protein, putative OS=Pe... 97 1e-17
F6R6F0_ORNAN (tr|F6R6F0) Uncharacterized protein OS=Ornithorhync... 97 2e-17
H3CDQ1_TETNG (tr|H3CDQ1) Uncharacterized protein (Fragment) OS=T... 97 2e-17
B4PYK8_DROYA (tr|B4PYK8) GE17898 OS=Drosophila yakuba GN=Dyak\GE... 96 3e-17
Q29GK5_DROPS (tr|Q29GK5) GA11389 OS=Drosophila pseudoobscura pse... 96 4e-17
K3WTT1_PYTUL (tr|K3WTT1) Uncharacterized protein OS=Pythium ulti... 96 5e-17
B4H144_DROPE (tr|B4H144) GL15811 OS=Drosophila persimilis GN=Dpe... 96 5e-17
F7INK6_CALJA (tr|F7INK6) Uncharacterized protein OS=Callithrix j... 95 7e-17
B4I6C1_DROSE (tr|B4I6C1) GM23054 OS=Drosophila sechellia GN=Dsec... 95 7e-17
B4R3B8_DROSI (tr|B4R3B8) GD17503 OS=Drosophila simulans GN=Dsim\... 95 1e-16
Q4T749_TETNG (tr|Q4T749) Chromosome undetermined SCAF8317, whole... 94 1e-16
B3N0K3_DROAN (tr|B3N0K3) GF21705 OS=Drosophila ananassae GN=Dana... 93 3e-16
B4M3Q5_DROVI (tr|B4M3Q5) GJ19256 OS=Drosophila virilis GN=Dvir\G... 93 3e-16
K7EQ23_HUMAN (tr|K7EQ23) Niemann-Pick C1 protein (Fragment) OS=H... 92 6e-16
B4DET3_HUMAN (tr|B4DET3) Niemann-Pick C1 protein OS=Homo sapiens... 92 6e-16
E2ARF1_CAMFO (tr|E2ARF1) Niemann-Pick C1 protein OS=Camponotus f... 91 1e-15
H3IPJ5_STRPU (tr|H3IPJ5) Uncharacterized protein OS=Strongylocen... 91 2e-15
A8IYI0_CHLRE (tr|A8IYI0) Sterol sensing domain protein (Fragment... 90 2e-15
D0P4C6_PHYIT (tr|D0P4C6) Resistance-Nodulation-Cell Division (RN... 90 3e-15
E4YLS2_OIKDI (tr|E4YLS2) Whole genome shotgun assembly, allelic ... 89 4e-15
K3WBN3_PYTUL (tr|K3WBN3) Uncharacterized protein OS=Pythium ulti... 88 9e-15
F1SSH5_PIG (tr|F1SSH5) Uncharacterized protein OS=Sus scrofa GN=... 87 2e-14
E9J040_SOLIN (tr|E9J040) Putative uncharacterized protein (Fragm... 87 2e-14
H9GW62_CANFA (tr|H9GW62) Uncharacterized protein OS=Canis famili... 86 5e-14
H2Z2C4_CIOSA (tr|H2Z2C4) Uncharacterized protein (Fragment) OS=C... 86 6e-14
J9IV70_9SPIT (tr|J9IV70) Sterol-sensing multi-domain protein OS=... 84 1e-13
Q6QVL7_ORNMO (tr|Q6QVL7) NPC1 (Precursor) OS=Ornithodoros moubat... 84 1e-13
L5LGZ5_MYODS (tr|L5LGZ5) Niemann-Pick C1-like protein 1 OS=Myoti... 84 2e-13
M4BQN4_HYAAE (tr|M4BQN4) Uncharacterized protein OS=Hyaloperonos... 83 2e-13
H3H061_PHYRM (tr|H3H061) Uncharacterized protein OS=Phytophthora... 83 3e-13
G1PCU2_MYOLU (tr|G1PCU2) Uncharacterized protein OS=Myotis lucif... 83 4e-13
G5A4B5_PHYSP (tr|G5A4B5) Putative uncharacterized protein (Fragm... 83 4e-13
H3GZW0_PHYRM (tr|H3GZW0) Uncharacterized protein OS=Phytophthora... 81 1e-12
H9JFQ1_BOMMO (tr|H9JFQ1) Uncharacterized protein OS=Bombyx mori ... 81 1e-12
K3WTQ3_PYTUL (tr|K3WTQ3) Uncharacterized protein OS=Pythium ulti... 80 2e-12
J9K7Y2_ACYPI (tr|J9K7Y2) Uncharacterized protein OS=Acyrthosipho... 79 5e-12
H2Z2C7_CIOSA (tr|H2Z2C7) Uncharacterized protein (Fragment) OS=C... 79 6e-12
G4YKV4_PHYSP (tr|G4YKV4) Patched family protein OS=Phytophthora ... 79 7e-12
E3LT08_CAERE (tr|E3LT08) CRE-NCR-2 protein OS=Caenorhabditis rem... 77 1e-11
M4C157_HYAAE (tr|M4C157) Uncharacterized protein OS=Hyaloperonos... 77 2e-11
G5A4B1_PHYSP (tr|G5A4B1) Putative uncharacterized protein OS=Phy... 77 2e-11
G7J4Q6_MEDTR (tr|G7J4Q6) F-box/LRR-repeat protein OS=Medicago tr... 76 3e-11
A7TSK4_VANPO (tr|A7TSK4) Putative uncharacterized protein (Fragm... 76 4e-11
G0N5H9_CAEBE (tr|G0N5H9) CBN-NCR-2 protein OS=Caenorhabditis bre... 75 7e-11
D0NHD0_PHYIT (tr|D0NHD0) Resistance-Nodulation-Cell Division (RN... 74 2e-10
M7WFU2_ENTHI (tr|M7WFU2) Niemann-Pick C1 protein, putative OS=En... 74 2e-10
N9UTI0_ENTHI (tr|N9UTI0) Niemann-Pick C1 protein, putative OS=En... 74 2e-10
M3TK92_ENTHI (tr|M3TK92) Niemann-Pick C1 protein, putative OS=En... 74 2e-10
M2S216_ENTHI (tr|M2S216) NiemannPick C1 protein, putative OS=Ent... 74 2e-10
C4M8X7_ENTHI (tr|C4M8X7) Niemann-Pick C1 protein, putative OS=En... 74 2e-10
B0X6W3_CULQU (tr|B0X6W3) Niemann-Pick C1 protein OS=Culex quinqu... 74 2e-10
G4YJ98_PHYSP (tr|G4YJ98) Patched family protein OS=Phytophthora ... 73 2e-10
K7H5X8_CAEJA (tr|K7H5X8) Uncharacterized protein (Fragment) OS=C... 73 4e-10
K7H5X9_CAEJA (tr|K7H5X9) Uncharacterized protein (Fragment) OS=C... 72 4e-10
B0E9R8_ENTDS (tr|B0E9R8) Niemann-Pick C1 protein, putative OS=En... 72 4e-10
K7H5X7_CAEJA (tr|K7H5X7) Uncharacterized protein OS=Caenorhabdit... 72 5e-10
K2GY84_ENTNP (tr|K2GY84) Niemann-Pick C1 protein, putative OS=En... 72 5e-10
F0WDX3_9STRA (tr|F0WDX3) ResistanceNodulationCell Division (RND)... 72 6e-10
>K7M447_SOYBN (tr|K7M447) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1284
Score = 920 bits (2378), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 455/578 (78%), Positives = 488/578 (84%), Gaps = 13/578 (2%)
Query: 8 IISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVK 67
I SV FLLQV +LS SP+ + + R+ HS EYCAMYDICGQ SDGK LNCPY SPSVK
Sbjct: 4 IFSVAFLLQVFLLSS-SPATSQHETFRAKHSEEYCAMYDICGQSSDGKALNCPYGSPSVK 62
Query: 68 PHDLLSAKIQSLCPTITGNVCCTEEQ-----LQAVPILVGCPACLRNFLNLFCELSCSPN 122
P DLLSAKIQSLCPTITGNVCCT +Q +QAVPILVGCPACLRNFLNLFCELSCSPN
Sbjct: 63 PDDLLSAKIQSLCPTITGNVCCTADQFDTLRVQAVPILVGCPACLRNFLNLFCELSCSPN 122
Query: 123 QSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANN 182
QSLFINVTSIS+V+GNMTVDGID Y+TETFGEGLY +CKDVKFGTMNTRAIDFVGAGA+N
Sbjct: 123 QSLFINVTSISEVNGNMTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASN 182
Query: 183 YKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXX 242
+KEWFAFLGQKVPPGFPGSPYSI FKTTILDSSPM+LMNASVYSCNDTSLG
Sbjct: 183 FKEWFAFLGQKVPPGFPGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSS 242
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGS 302
I++GSLKVRCVD S+A+LYIVLVFVLFGW GS
Sbjct: 243 PVCSGSEPSPPRKDPCSIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGS 302
Query: 303 SAEPLL---VSEGRSFTNLPKDG----EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA 355
EPLL V EG SF NL KDG EV IDPQ QN VQ+SF+Q LS+FYR YGRWA
Sbjct: 303 GVEPLLDDMVDEGSSFANLQKDGTHPAEVQQIDPQGQNVVQFSFVQGCLSSFYRTYGRWA 362
Query: 356 ARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIE 415
R+PTIVLCSSL IV+LLC GLLRF VETRPEKLWVGP SKAAEEKEFFDSHLAPFYRIE
Sbjct: 363 TRKPTIVLCSSLTIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIE 422
Query: 416 QLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDC 475
QLIIAT+PES+HGKPPSI+T++NIELLFEIQEKVD IRANYSGLLVSLSDICLKPLG+DC
Sbjct: 423 QLIIATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDC 482
Query: 476 ATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNY 535
A+QSILQYFQMDPDN+DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNY
Sbjct: 483 ASQSILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNY 542
Query: 536 SEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
SEASAF+ITYPVNNA+TKVGDENGKAIAWEKAFIQLAK
Sbjct: 543 SEASAFVITYPVNNAITKVGDENGKAIAWEKAFIQLAK 580
>K7M448_SOYBN (tr|K7M448) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1281
Score = 917 bits (2370), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 453/575 (78%), Positives = 486/575 (84%), Gaps = 10/575 (1%)
Query: 8 IISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVK 67
I SV FLLQV +LS SP+ + + R+ HS EYCAMYDICGQ SDGK LNCPY SPSVK
Sbjct: 4 IFSVAFLLQVFLLSS-SPATSQHETFRAKHSEEYCAMYDICGQSSDGKALNCPYGSPSVK 62
Query: 68 PHDLLSAKIQSLCPTITGNVCCTEEQ-----LQAVPILVGCPACLRNFLNLFCELSCSPN 122
P DLLSAKIQSLCPTITGNVCCT +Q +QAVPILVGCPACLRNFLNLFCELSCSPN
Sbjct: 63 PDDLLSAKIQSLCPTITGNVCCTADQFDTLRVQAVPILVGCPACLRNFLNLFCELSCSPN 122
Query: 123 QSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANN 182
QSLFINVTSIS+V+GNMTVDGID Y+TETFGEGLY +CKDVKFGTMNTRAIDFVGAGA+N
Sbjct: 123 QSLFINVTSISEVNGNMTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASN 182
Query: 183 YKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXX 242
+KEWFAFLGQKVPPGFPGSPYSI FKTTILDSSPM+LMNASVYSCNDTSLG
Sbjct: 183 FKEWFAFLGQKVPPGFPGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSS 242
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGS 302
I++GSLKVRCVD S+A+LYIVLVFVLFGW GS
Sbjct: 243 PVCSGSEPSPPRKDPCSIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGS 302
Query: 303 SAEPLL---VSEGRSFTNLPKDG-EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARR 358
EPLL V EG SF NL KDG IDPQ QN VQ+SF+Q LS+FYR YGRWA R+
Sbjct: 303 GVEPLLDDMVDEGSSFANLQKDGTHPAEIDPQGQNVVQFSFVQGCLSSFYRTYGRWATRK 362
Query: 359 PTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLI 418
PTIVLCSSL IV+LLC GLLRF VETRPEKLWVGP SKAAEEKEFFDSHLAPFYRIEQLI
Sbjct: 363 PTIVLCSSLTIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLI 422
Query: 419 IATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQ 478
IAT+PES+HGKPPSI+T++NIELLFEIQEKVD IRANYSGLLVSLSDICLKPLG+DCA+Q
Sbjct: 423 IATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDCASQ 482
Query: 479 SILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 538
SILQYFQMDPDN+DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA
Sbjct: 483 SILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 542
Query: 539 SAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
SAF+ITYPVNNA+TKVGDENGKAIAWEKAFIQLAK
Sbjct: 543 SAFVITYPVNNAITKVGDENGKAIAWEKAFIQLAK 577
>K7KBT5_SOYBN (tr|K7KBT5) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1268
Score = 912 bits (2358), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 454/581 (78%), Positives = 486/581 (83%), Gaps = 16/581 (2%)
Query: 8 IISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVK 67
I SV FLLQV +LS SP+ + + R+ HS EYCAMYDICGQRSDGK LNCPY SPSVK
Sbjct: 4 IFSVTFLLQVFLLSS-SPAASQRETYRAKHSEEYCAMYDICGQRSDGKALNCPYGSPSVK 62
Query: 68 PHDLLSAKIQSLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSC 119
P DLLSAKIQSLCPTITGNVCCT +Q QA+PILVGCPACLRNFLNLFCELSC
Sbjct: 63 PDDLLSAKIQSLCPTITGNVCCTADQFDTLRVQVQQAIPILVGCPACLRNFLNLFCELSC 122
Query: 120 SPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAG 179
SPNQSLFINVTSIS+VDGN TVDGID ++TETFG+GLY +CKDVKFGTMNTRAIDFVGAG
Sbjct: 123 SPNQSLFINVTSISEVDGNTTVDGIDYHLTETFGQGLYESCKDVKFGTMNTRAIDFVGAG 182
Query: 180 ANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXX 239
A+N+KEW FLGQKVPPGFPGSPYSI FKT ILDSSPM+LMNASVYSCNDTSLG
Sbjct: 183 ASNFKEWAEFLGQKVPPGFPGSPYSILFKTAILDSSPMKLMNASVYSCNDTSLGCSCGDC 242
Query: 240 XXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXX 299
I +GSLKVRCVD S+A+LYIVLVFVLFGW
Sbjct: 243 PSSPVCSGSEPSPPRKDPCSIGIGSLKVRCVDFSIAILYIVLVFVLFGWALLQRTRGRRR 302
Query: 300 XGSSAEPLL---VSEGRSFTNLPKDG----EVLVIDPQRQNEVQYSFIQEWLSNFYRAYG 352
GSSAEPLL V EG SF NLPKDG EV IDPQ QN VQ+SF+Q LS+FYR YG
Sbjct: 303 LGSSAEPLLDDMVGEGSSFANLPKDGTHPAEVQWIDPQGQNVVQFSFVQGCLSSFYRTYG 362
Query: 353 RWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFY 412
RWAAR+PTIVLCSSLAIV+LLC GLLRF VETRPEKLWVGP SKAAEEKEFFDSHLAPFY
Sbjct: 363 RWAARKPTIVLCSSLAIVVLLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFY 422
Query: 413 RIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG 472
RIEQLIIAT+PES+HGKPPSI+T++NIELLFEIQEKVD IRANYSG LVSLSDICLKPLG
Sbjct: 423 RIEQLIIATIPESKHGKPPSIITEENIELLFEIQEKVDGIRANYSGFLVSLSDICLKPLG 482
Query: 473 EDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG 532
+DCATQSILQYFQMDPDN+DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG
Sbjct: 483 DDCATQSILQYFQMDPDNYDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG 542
Query: 533 NNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
NNYSEASAF+ITYPVNNA+TKVG ENGKAIAWEKAFIQLAK
Sbjct: 543 NNYSEASAFVITYPVNNAITKVGGENGKAIAWEKAFIQLAK 583
>B9HPX9_POPTR (tr|B9HPX9) Cholesterol transport protein OS=Populus trichocarpa
GN=POPTRDRAFT_721264 PE=4 SV=1
Length = 1223
Score = 740 bits (1910), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 364/543 (67%), Positives = 423/543 (77%), Gaps = 21/543 (3%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG RSDGKVLNCP+P+ SVKP D SAKIQSLCP I+GNVCCTE Q Q
Sbjct: 1 MYDICGARSDGKVLNCPFPTSSVKPDDYFSAKIQSLCPAISGNVCCTETQFDTLRAQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P+LVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS+V+GN+TVDGI YVT+ FGE
Sbjct: 61 AIPLLVGCPACLRNFLNLFCELSCSPNQSLFINVTSISEVNGNLTVDGIAYYVTDDFGER 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY +CKDVKFGTMNTRAIDFVG GANN+KEWFAF+GQK PPGFPGSPY IDFK+TI DSS
Sbjct: 121 LYDSCKDVKFGTMNTRAIDFVGGGANNFKEWFAFIGQKAPPGFPGSPYEIDFKSTIPDSS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXX-XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSL 274
M MN S YSC DTSLG I++G LKV+C+D S+
Sbjct: 181 KMVPMNVSAYSCGDTSLGCSCGDCPLAPACSSSEPPSPPKKESCLIRIGPLKVKCLDFSV 240
Query: 275 AVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS----EGRSFTNLPKDGEVLVIDPQ 330
A+LYI+LVF GW +S EPLL S E S T + KDG+V P+
Sbjct: 241 AILYIILVFAFLGW-ASLNRTRERRAAASKEPLLSSMDEVEADS-TEIQKDGKV----PR 294
Query: 331 RQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLW 390
N Q +Q +S+FYR YG+W AR PT+VLCSS+A+V++LC GL+ F VETRPEKLW
Sbjct: 295 LINRFQLDGVQGHMSSFYRNYGKWVARNPTLVLCSSVAVVLVLCIGLICFKVETRPEKLW 354
Query: 391 VGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVD 450
VGP SKAAEEK FFDSHLAPFYRIEQLI+ATLP+S++ K SIVTD+NI+LLFEIQ+KVD
Sbjct: 355 VGPGSKAAEEKHFFDSHLAPFYRIEQLILATLPDSKNDKRNSIVTDENIQLLFEIQKKVD 414
Query: 451 EIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTST 510
IRANYSG +VSL+DICLKPLG+DCATQS+LQYF+MDP+N+D+YGGVEHAEYCFQHYT+
Sbjct: 415 GIRANYSGSVVSLTDICLKPLGDDCATQSLLQYFKMDPENYDDYGGVEHAEYCFQHYTTA 474
Query: 511 ETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQ 570
+TC SAFKAPL+P+TALGGFSGNNYSEASAF++TYPVNNA+ + G NGKA+AWEKAFI+
Sbjct: 475 DTCMSAFKAPLDPSTALGGFSGNNYSEASAFVVTYPVNNAIDEAG--NGKAVAWEKAFIR 532
Query: 571 LAK 573
L K
Sbjct: 533 LVK 535
>F6I0S6_VITVI (tr|F6I0S6) Putative uncharacterized protein OS=Vitis vinifera
GN=VIT_03s0038g03730 PE=4 SV=1
Length = 1291
Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 361/578 (62%), Positives = 435/578 (75%), Gaps = 24/578 (4%)
Query: 14 LLQVLIL-SWFSPSLTAAQI-------SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPS 65
LLQVLI S T +Q S HS EYCAMYDICG+RSDGKVLNCPY +P+
Sbjct: 20 LLQVLIFASLLGAEKTDSQFLLFPNATSGERHSPEYCAMYDICGERSDGKVLNCPYGTPA 79
Query: 66 VKPHDLLSAKIQSLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCEL 117
VKP + LSAKIQSLCP I+GNVCCTE Q QA+P LVGCPACLRNFLNLFCEL
Sbjct: 80 VKPDEFLSAKIQSLCPMISGNVCCTEAQFDTLRAQVQQAIPFLVGCPACLRNFLNLFCEL 139
Query: 118 SCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVG 177
SCSPNQSLFINVTSI++ + + TVDGID YV++ FGEGLY++CKDVKFGTMNTRAI F+G
Sbjct: 140 SCSPNQSLFINVTSIAKGNCSSTVDGIDFYVSDAFGEGLYNSCKDVKFGTMNTRAIQFIG 199
Query: 178 AGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXX 237
AGA N+KEWFAF+GQ+ G PGSPY+I+FK+ +SS MELMN S+YSC DTSLG
Sbjct: 200 AGARNFKEWFAFIGQQADLGMPGSPYAINFKSRP-ESSGMELMNVSIYSCGDTSLGCSCG 258
Query: 238 XXXXXXXXXXXXXXX-XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGW-IXXXXXX 295
I +GS+KV+C++ SLA+LYIVLV FGW +
Sbjct: 259 DCPSSPVCSDYEPPSPQQKDACSISLGSVKVKCIEFSLAILYIVLVSAFFGWGLFHRTRE 318
Query: 296 XXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA 355
S+ +PLL E T L +V + PQ N VQ S +Q ++S+FYR YG W
Sbjct: 319 RRRIPASNMKPLLNFEDEKLTTL----KVHEMVPQETN-VQLSAVQGYMSSFYRQYGTWV 373
Query: 356 ARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIE 415
A+ P++VLC SLA+V++LC GL+RF VETRPEKLWVGP S+AAEEK FFDSHLAPFYRIE
Sbjct: 374 AKNPSLVLCMSLAVVLILCLGLIRFKVETRPEKLWVGPGSRAAEEKNFFDSHLAPFYRIE 433
Query: 416 QLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDC 475
QLI+AT+P+ + GK SIV+DDNI+LLFEIQ+KVD +RANYSG +VSL+DICLKP+G+DC
Sbjct: 434 QLILATMPDIKSGKSSSIVSDDNIQLLFEIQKKVDGLRANYSGSVVSLTDICLKPMGQDC 493
Query: 476 ATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNY 535
ATQS+LQYF+MDP+N+ YGGV+H EYCFQHYT+ +TC SAFKAPL+P+TALGGFSGNNY
Sbjct: 494 ATQSVLQYFKMDPENYYGYGGVQHVEYCFQHYTTADTCMSAFKAPLDPSTALGGFSGNNY 553
Query: 536 SEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+EASAFI+TYPVNNA+ G+ENGKA+AWEKAF+QL K
Sbjct: 554 TEASAFIVTYPVNNAIGGAGNENGKAVAWEKAFVQLVK 591
>F4JTN0_ARATH (tr|F4JTN0) Patched family protein OS=Arabidopsis thaliana
GN=AT4G38350 PE=2 SV=1
Length = 1273
Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 354/577 (61%), Positives = 432/577 (74%), Gaps = 12/577 (2%)
Query: 7 AIISVGFLLQVLILSWF-SPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPS 65
AI + LLQ+ S + +LT ++ S + HS EYCAMYDICG RSDGKVLNCPY SPS
Sbjct: 2 AIPTKLLLLQLFTFSLLLTANLTHSEPSNNRHSKEYCAMYDICGHRSDGKVLNCPYASPS 61
Query: 66 VKPHDLLSAKIQSLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCEL 117
++P +L SAKIQSLCPTI+GNVCCTE Q QAVP LVGCPACLRNFLNLFCEL
Sbjct: 62 IQPDELFSAKIQSLCPTISGNVCCTETQFDTLRSQVQQAVPFLVGCPACLRNFLNLFCEL 121
Query: 118 SCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVG 177
SCSPNQSLFINVTS+++V GN+TVDGID ++T+TFGEGLY +CK+VKFGTMNTRAI+FVG
Sbjct: 122 SCSPNQSLFINVTSVAEVSGNLTVDGIDYHITDTFGEGLYESCKEVKFGTMNTRAINFVG 181
Query: 178 AGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXX 237
GA N++EWF F+GQK P GFPGSPY+I+FK++I +SS M MN SVYSC DTSLG
Sbjct: 182 GGAKNFREWFTFIGQKAPSGFPGSPYAINFKSSIPESSAMVPMNVSVYSCGDTSLGCSCG 241
Query: 238 XXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXX 296
I++G LKVRC++LS+A++Y++LV FGW
Sbjct: 242 DCPSSPACSSPEPLPPHDEDSCSIRIGPLKVRCIELSMALVYVLLVSCFFGWAGLNRRRN 301
Query: 297 XXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAA 356
S++PLL N +L + QR Q S +Q +++ FYR+YG W A
Sbjct: 302 TTQPLDSSKPLLHPVEEDGINSEMKENILGVKVQRH--AQLSPVQRYMAKFYRSYGSWIA 359
Query: 357 RRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ 416
R P++VL S+AIV+ LC GL F VETRPEKLWVGPESKAAEEK+FFD+HL+PFYRIEQ
Sbjct: 360 RNPSLVLFMSVAIVLALCSGLYNFKVETRPEKLWVGPESKAAEEKKFFDTHLSPFYRIEQ 419
Query: 417 LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCA 476
LI+AT+P+ + G+ PSIVTD+NI LLF+IQ+KVD+IR NYSG VSL DICLKPLGEDCA
Sbjct: 420 LILATVPDPKSGRAPSIVTDENILLLFDIQQKVDQIRGNYSGSEVSLPDICLKPLGEDCA 479
Query: 477 TQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYS 536
TQSILQYF+MD FD+YGGVEHAEYCFQHYTS+ETC SAF+AP++P+ LGGFSGNNYS
Sbjct: 480 TQSILQYFKMDSGTFDDYGGVEHAEYCFQHYTSSETCLSAFQAPVDPSAVLGGFSGNNYS 539
Query: 537 EASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
EA+AF++TYPVNN + +EN +A+AWEK+FIQLAK
Sbjct: 540 EATAFVVTYPVNNVIGDSSNENARAVAWEKSFIQLAK 576
>R0F2L3_9BRAS (tr|R0F2L3) Uncharacterized protein OS=Capsella rubella
GN=CARUB_v10003998mg PE=4 SV=1
Length = 1277
Score = 725 bits (1872), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 350/547 (63%), Positives = 416/547 (76%), Gaps = 13/547 (2%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HS ++CAMYDICG+RSDGKVLNCPY SPS+KP +L SAKIQSLCPTITG VCCTE Q
Sbjct: 39 HSQDFCAMYDICGERSDGKVLNCPYASPSIKPDELFSAKIQSLCPTITGKVCCTETQFDT 98
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QAVP LVGCPACLRNFLNLFCELSCSPNQSLFINVTSI++V GNMTVDGID ++
Sbjct: 99 LRSQVQQAVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSIAEVSGNMTVDGIDYHI 158
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+TFG+GLY +CK+VKFGTMNTRAI+FVG GA N++EWF F+GQK PPGFPGSPY+I+FK
Sbjct: 159 TDTFGKGLYESCKEVKFGTMNTRAINFVGGGAQNFREWFTFIGQKAPPGFPGSPYAINFK 218
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKV 267
+ +S M MN SVYSC DTSLG I++G LKV
Sbjct: 219 SNTPESDVMVPMNLSVYSCGDTSLGCSCGDCPSSPACSSPEPLPPREEESCSIRIGPLKV 278
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS-EGRSFTNLPKDGEVLV 326
RC++LS+ ++YI+LV FGW G S+EPLL E T+ PK+ + V
Sbjct: 279 RCIELSMVLVYILLVSCFFGWGALNRRRDITKPGDSSEPLLHPLEEDGITSEPKESTLGV 338
Query: 327 IDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRP 386
+ + Q S +Q ++ NFYR YG W AR P++VL S+AIV+ L GL F VETRP
Sbjct: 339 ---KVERHAQVSPVQRYMENFYRTYGSWIARNPSLVLFMSVAIVLALSSGLFNFEVETRP 395
Query: 387 EKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQ 446
EKLWVGP SKAAEEK+FFDSHL+PFYRIEQLI+AT+P+ + G+ PSIVTD+NI LLFEIQ
Sbjct: 396 EKLWVGPGSKAAEEKKFFDSHLSPFYRIEQLILATVPDPKSGRAPSIVTDENILLLFEIQ 455
Query: 447 EKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQH 506
EKVD+IR NYSG VSL+DICLKPLGEDCATQSILQYF+MDP NFD+YGGVEHAEYCFQH
Sbjct: 456 EKVDQIRGNYSGSKVSLTDICLKPLGEDCATQSILQYFKMDPGNFDDYGGVEHAEYCFQH 515
Query: 507 YTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEK 566
YTS+E C SAF+AP++P+ LGGFSGNNYSEA+AF++TYPVNN + +EN AIAWE+
Sbjct: 516 YTSSEMCLSAFQAPVDPSAVLGGFSGNNYSEATAFVVTYPVNNVIGDSSNENAMAIAWEQ 575
Query: 567 AFIQLAK 573
+FIQLAK
Sbjct: 576 SFIQLAK 582
>D7UDA3_VITVI (tr|D7UDA3) Putative uncharacterized protein OS=Vitis vinifera
GN=VIT_18s0122g01280 PE=4 SV=1
Length = 1242
Score = 722 bits (1863), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 345/545 (63%), Positives = 421/545 (77%), Gaps = 16/545 (2%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG+RSDGKVLNCPY SPSVKP DLLS+KIQS+CPTI+GNVCCTE Q Q
Sbjct: 1 MYDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTISGNVCCTEAQFDTLRTQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P LVGCPACLRNFLNLFCEL+CSPNQSLFINVTS+S+V+ N+TVDGI+ +T+ FGEG
Sbjct: 61 AIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY++CKDVKFGTMNTRAIDF+GAGA +KEWFAF+G + P PGSPY+I+F+ +I +SS
Sbjct: 121 LYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQPSIAESS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXX-XXXXXXXXXIKMGSLKVRCVDLSL 274
M+ MN S YSC D SLG +++GSLK +C++ SL
Sbjct: 181 GMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIGSLKAKCIEFSL 240
Query: 275 AVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF--TNLPKD----GEVLVID 328
A+LYI+LV + FGW L V +G N PKD ++L
Sbjct: 241 AILYIILVTIFFGWGLFHRTRERNPAPRMKPMLNVMDGSELHSMNRPKDENLSSQMLEDV 300
Query: 329 PQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEK 388
PQ +N VQ S +Q ++SNFYR YG W AR PTI+LCSSLAIV++LC GL+RF VETRPEK
Sbjct: 301 PQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGLIRFKVETRPEK 360
Query: 389 LWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEK 448
LWVGP SKAAEEK+FFDSHLAPFYRIEQL++AT+P++ +G PSIVT++NI+LLFEIQ+K
Sbjct: 361 LWVGPGSKAAEEKQFFDSHLAPFYRIEQLVLATIPDA-NGISPSIVTENNIKLLFEIQKK 419
Query: 449 VDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYT 508
VD +RAN+SG ++SL+DIC+KPLG+DCATQS+LQYF+MD N+D+YGGV+H EYCFQHYT
Sbjct: 420 VDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGVQHVEYCFQHYT 479
Query: 509 STETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
S +TC SAFKAPL+P+TALGGFSGNNYSEASAFI+TYPVNNA+ K G+E GKA+AWEKAF
Sbjct: 480 SADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNETGKAVAWEKAF 539
Query: 569 IQLAK 573
IQ+ K
Sbjct: 540 IQIVK 544
>M5W6J9_PRUPE (tr|M5W6J9) Uncharacterized protein OS=Prunus persica
GN=PRUPE_ppa000346mg PE=4 SV=1
Length = 1261
Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 352/564 (62%), Positives = 423/564 (75%), Gaps = 34/564 (6%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-----QAVP 98
MYDICG+RSDGKVLNCPY SPSVKP +L SAKIQSLCPTI+GNVCCTE Q QA+P
Sbjct: 1 MYDICGERSDGKVLNCPYGSPSVKPDELFSAKIQSLCPTISGNVCCTELQFETLRAQAIP 60
Query: 99 ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYS 158
LVGCPACLRNFLNLFCELSCSP+QSLFINVTS+S+V+GN TVD ID Y+ +TFGEGLY+
Sbjct: 61 FLVGCPACLRNFLNLFCELSCSPSQSLFINVTSVSEVNGNTTVDAIDFYIADTFGEGLYN 120
Query: 159 ACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPME 218
+CKDVKFGTMNTRAI+F+GAGA N++EWF F+G+K GFPGSPY+IDFK T+ +SS ME
Sbjct: 121 SCKDVKFGTMNTRAIEFIGAGAKNFEEWFDFIGEKAALGFPGSPYAIDFKLTVPESSRME 180
Query: 219 LMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLY 278
LMN SVYSC DTSLG I++ S++V+C+D S+A+LY
Sbjct: 181 LMNVSVYSCADTSLGCSCGDCPSSQECSNPEPPPQKKEPCSIRILSIEVKCIDFSVAILY 240
Query: 279 IVLVFVLFGWIXXXXXXXXXXXGSSAEPLL---VSEGRSFTNLPKDGEVL---------- 325
I+L+ FGW SS EPLL +G NL +D V+
Sbjct: 241 ILLISAFFGWGLFHRTSERRRVESSKEPLLNVIHDDGIDSVNLQRDESVVTKVSVLSCLA 300
Query: 326 -VIDPQRQNEVQYSFIQEWLSNFY---------------RAYGRWAARRPTIVLCSSLAI 369
+I + E + S I L F+ ++YG W +R PT VL SS+AI
Sbjct: 301 YLITLGTKKEPKESCISYGLGAFFVSMHYNNYFYIGIEMQSYGSWVSRNPTFVLFSSVAI 360
Query: 370 VILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGK 429
V++LC GL+RF VETRPEKLWVG SKAAEEK+FFDSHLAPFYRIEQLIIAT+P+ +HGK
Sbjct: 361 VLVLCVGLVRFKVETRPEKLWVGRGSKAAEEKQFFDSHLAPFYRIEQLIIATVPDPKHGK 420
Query: 430 PPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPD 489
PSIVTDDNI+LLF+IQ KVD +RANYSG +V+L++ICLKP+G+DCATQSILQYF+MDP+
Sbjct: 421 SPSIVTDDNIQLLFDIQNKVDGVRANYSGSMVALTEICLKPVGQDCATQSILQYFKMDPE 480
Query: 490 NFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN 549
N+D+YGGV HAEYCFQHYTS +TC SAF+APL+P+TALGGFSGNNY+EASAFI+TYPVNN
Sbjct: 481 NYDSYGGVVHAEYCFQHYTSADTCLSAFQAPLDPSTALGGFSGNNYTEASAFIVTYPVNN 540
Query: 550 ALTKVGDENGKAIAWEKAFIQLAK 573
A+ VG+EN KA+AWEKAFIQLAK
Sbjct: 541 AVDDVGNENAKALAWEKAFIQLAK 564
>F4JTN1_ARATH (tr|F4JTN1) Patched family protein OS=Arabidopsis thaliana
GN=AT4G38350 PE=2 SV=1
Length = 1297
Score = 714 bits (1842), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 354/601 (58%), Positives = 432/601 (71%), Gaps = 36/601 (5%)
Query: 7 AIISVGFLLQVLILSWF-SPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPS 65
AI + LLQ+ S + +LT ++ S + HS EYCAMYDICG RSDGKVLNCPY SPS
Sbjct: 2 AIPTKLLLLQLFTFSLLLTANLTHSEPSNNRHSKEYCAMYDICGHRSDGKVLNCPYASPS 61
Query: 66 VKPHDLLSAKIQSLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCEL 117
++P +L SAKIQSLCPTI+GNVCCTE Q QAVP LVGCPACLRNFLNLFCEL
Sbjct: 62 IQPDELFSAKIQSLCPTISGNVCCTETQFDTLRSQVQQAVPFLVGCPACLRNFLNLFCEL 121
Query: 118 SCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVG 177
SCSPNQSLFINVTS+++V GN+TVDGID ++T+TFGEGLY +CK+VKFGTMNTRAI+FVG
Sbjct: 122 SCSPNQSLFINVTSVAEVSGNLTVDGIDYHITDTFGEGLYESCKEVKFGTMNTRAINFVG 181
Query: 178 AGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXX 237
GA N++EWF F+GQK P GFPGSPY+I+FK++I +SS M MN SVYSC DTSLG
Sbjct: 182 GGAKNFREWFTFIGQKAPSGFPGSPYAINFKSSIPESSAMVPMNVSVYSCGDTSLGCSCG 241
Query: 238 XXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXX 296
I++G LKVRC++LS+A++Y++LV FGW
Sbjct: 242 DCPSSPACSSPEPLPPHDEDSCSIRIGPLKVRCIELSMALVYVLLVSCFFGWAGLNRRRN 301
Query: 297 XXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAA 356
S++PLL N +L + QR Q S +Q +++ FYR+YG W A
Sbjct: 302 TTQPLDSSKPLLHPVEEDGINSEMKENILGVKVQRH--AQLSPVQRYMAKFYRSYGSWIA 359
Query: 357 RRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ 416
R P++VL S+AIV+ LC GL F VETRPEKLWVGPESKAAEEK+FFD+HL+PFYRIEQ
Sbjct: 360 RNPSLVLFMSVAIVLALCSGLYNFKVETRPEKLWVGPESKAAEEKKFFDTHLSPFYRIEQ 419
Query: 417 LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCA 476
LI+AT+P+ + G+ PSIVTD+NI LLF+IQ+KVD+IR NYSG VSL DICLKPLGEDCA
Sbjct: 420 LILATVPDPKSGRAPSIVTDENILLLFDIQQKVDQIRGNYSGSEVSLPDICLKPLGEDCA 479
Query: 477 TQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYS 536
TQSILQYF+MD FD+YGGVEHAEYCFQHYTS+ETC SAF+AP++P+ LGGFSGNNYS
Sbjct: 480 TQSILQYFKMDSGTFDDYGGVEHAEYCFQHYTSSETCLSAFQAPVDPSAVLGGFSGNNYS 539
Query: 537 E------------------------ASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLA 572
E A+AF++TYPVNN + +EN +A+AWEK+FIQLA
Sbjct: 540 EVMVSELGCSVPFDCYSDVKRTLFQATAFVVTYPVNNVIGDSSNENARAVAWEKSFIQLA 599
Query: 573 K 573
K
Sbjct: 600 K 600
>K7M449_SOYBN (tr|K7M449) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1146
Score = 714 bits (1842), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 350/442 (79%), Positives = 374/442 (84%), Gaps = 7/442 (1%)
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
MTVDGID Y+TETFGEGLY +CKDVKFGTMNTRAIDFVGAGA+N+KEWFAFLGQKVPPGF
Sbjct: 1 MTVDGIDYYITETFGEGLYESCKDVKFGTMNTRAIDFVGAGASNFKEWFAFLGQKVPPGF 60
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
PGSPYSI FKTTILDSSPM+LMNASVYSCNDTSLG
Sbjct: 61 PGSPYSILFKTTILDSSPMKLMNASVYSCNDTSLGCSCGDCPSSPVCSGSEPSPPRKDPC 120
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL---VSEGRSF 315
I++GSLKVRCVD S+A+LYIVLVFVLFGW GS EPLL V EG SF
Sbjct: 121 SIRIGSLKVRCVDFSMAILYIVLVFVLFGWALLQRTRGRRRLGSGVEPLLDDMVDEGSSF 180
Query: 316 TNLPKDG----EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
NL KDG EV IDPQ QN VQ+SF+Q LS+FYR YGRWA R+PTIVLCSSL IV+
Sbjct: 181 ANLQKDGTHPAEVQQIDPQGQNVVQFSFVQGCLSSFYRTYGRWATRKPTIVLCSSLTIVV 240
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
LLC GLLRF VETRPEKLWVGP SKAAEEKEFFDSHLAPFYRIEQLIIAT+PES+HGKPP
Sbjct: 241 LLCLGLLRFEVETRPEKLWVGPGSKAAEEKEFFDSHLAPFYRIEQLIIATIPESKHGKPP 300
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
SI+T++NIELLFEIQEKVD IRANYSGLLVSLSDICLKPLG+DCA+QSILQYFQMDPDN+
Sbjct: 301 SIITEENIELLFEIQEKVDGIRANYSGLLVSLSDICLKPLGDDCASQSILQYFQMDPDNY 360
Query: 492 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAL 551
DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF+ITYPVNNA+
Sbjct: 361 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFVITYPVNNAI 420
Query: 552 TKVGDENGKAIAWEKAFIQLAK 573
TKVGDENGKAIAWEKAFIQLAK
Sbjct: 421 TKVGDENGKAIAWEKAFIQLAK 442
>M4D2P3_BRARP (tr|M4D2P3) Uncharacterized protein OS=Brassica rapa subsp.
pekinensis GN=Bra010746 PE=4 SV=1
Length = 1268
Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 345/548 (62%), Positives = 415/548 (75%), Gaps = 14/548 (2%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HSN+YCAMYDICGQR+DGKVLNCPY SPSVKP DL SAKIQSLCPTITGNVCCTE Q
Sbjct: 25 HSNDYCAMYDICGQRTDGKVLNCPYASPSVKPDDLFSAKIQSLCPTITGNVCCTETQFDT 84
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QAVP LVGCPACLRNFLNLFCELSCSPNQSLFINVTS+++V GN+TVDGID ++
Sbjct: 85 LRSQVQQAVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVAEVGGNLTVDGIDYHI 144
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FGEGLY +CK+VKFGTMNTRAI+FVG GA N++EWFAF+GQK PPGFPGSPY+I+FK
Sbjct: 145 TDMFGEGLYESCKEVKFGTMNTRAINFVGGGAQNFREWFAFIGQKAPPGFPGSPYAINFK 204
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXX--XXXXXXXXXXXXXXXXXXXXXIKMGSLK 266
++ + S M MN S YSC DTSLG ++G LK
Sbjct: 205 SSSPELSAMAPMNLSTYSCGDTSLGCSCGDCPSSPACSSPEPLPPPHEEDSCSFRLGPLK 264
Query: 267 VRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL-VSEGRSFTNLPKDGEVL 325
VRC++LS+A+LYI+LV FGW S+E L+ + EG + K+ +
Sbjct: 265 VRCIELSMALLYILLVSSFFGWATFSRTRDITQPDGSSESLVRLLEGDGINSELKESTLG 324
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
V + + S +Q +++ FY++YG W AR P++VL S+AIV+ L GLL F VETR
Sbjct: 325 V---KGKRHAHLSPVQRYMATFYKSYGSWIARNPSLVLFISVAIVLALSSGLLHFKVETR 381
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
PEKLWVGP SKAAEEK+FFDSHL+PFYRIEQLI+AT+P+ + GK PSIVT++NI LLF+I
Sbjct: 382 PEKLWVGPSSKAAEEKKFFDSHLSPFYRIEQLILATVPDPKTGKAPSIVTEENILLLFDI 441
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
QEKVD+IR NYSG V L+DICLKPLGEDCATQSILQYF+MD N+D YGGVEHAEYCFQ
Sbjct: 442 QEKVDQIRGNYSGSEVPLTDICLKPLGEDCATQSILQYFKMDVGNYDEYGGVEHAEYCFQ 501
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
HYTS+E C SAF+AP++P+ LGGFSG+NYSEA+AF+ITYPVNN + +EN +AIAWE
Sbjct: 502 HYTSSELCLSAFQAPVDPSAVLGGFSGSNYSEATAFVITYPVNNIVGDSSNENARAIAWE 561
Query: 566 KAFIQLAK 573
K+FIQLAK
Sbjct: 562 KSFIQLAK 569
>K4BVX6_SOLLC (tr|K4BVX6) Uncharacterized protein OS=Solanum lycopersicum
GN=Solyc04g082490.2 PE=4 SV=1
Length = 1294
Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 350/599 (58%), Positives = 430/599 (71%), Gaps = 29/599 (4%)
Query: 1 MENMSTAIISVGFL--------LQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRS 52
ME S+ I + FL QVL + + + T H+ YC+MYDICG RS
Sbjct: 1 MEEFSSRAIRLHFLRISFSISLFQVLFIGYTVTAQTTNSSGIERHAEGYCSMYDICGARS 60
Query: 53 DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------QAVPILVGCP 104
DGKVLNCP+ SPSVKP +LLS+KIQSLCPTITGNVCCTE Q QA+P LVGCP
Sbjct: 61 DGKVLNCPFGSPSVKPGELLSSKIQSLCPTITGNVCCTETQFDTLRSQVQQAIPFLVGCP 120
Query: 105 ACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVK 164
ACLRNFLNLFCEL+CSPNQS FINVTSIS+V N TV+GID ++T+TFGEGL+ +CKDVK
Sbjct: 121 ACLRNFLNLFCELTCSPNQSQFINVTSISKVKKNSTVNGIDFFITDTFGEGLFESCKDVK 180
Query: 165 FGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASV 224
FGTMNTRAI+F+GAGA N++EW+AF+G+ PPG PGSPY+I+F +T +SS M+ MN S
Sbjct: 181 FGTMNTRAIEFIGAGAKNFREWYAFIGRLAPPGVPGSPYAINFNSTAPESSGMKPMNVST 240
Query: 225 YSCNDTSLGXXXXXXXXXXXXXXXXXX-XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVF 283
YSC+DTSLG ++ GSLKV+C+++++ +LY+VLV
Sbjct: 241 YSCSDTSLGCSCGDCPSASVCSSSAPPPAQTEGSCSVRFGSLKVKCIEVAVTILYVVLVS 300
Query: 284 VLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT---------NLPKDGEVLVIDPQRQNE 334
V GW S +PL+ + G N+P ++L PQ +
Sbjct: 301 VFLGW-GFLHKKREETPVSRTKPLISATGNGVIRQSSRQKDENIPM--QMLEDVPQISSG 357
Query: 335 VQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPE 394
VQ S +Q ++S FYR YG W AR P +VLCSSL IV++LC GL RF VETRPEKLWVG
Sbjct: 358 VQLSIVQGYMSKFYRRYGTWVARNPILVLCSSLFIVLVLCLGLFRFKVETRPEKLWVGHG 417
Query: 395 SKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRA 454
S+AAEEK FFDSHLAPFYRIEQLII T+ ++++GK P IVT+DN++LLF+IQ+K+D I+A
Sbjct: 418 SRAAEEKLFFDSHLAPFYRIEQLIIGTISDADNGKAPPIVTEDNMKLLFDIQKKIDAIQA 477
Query: 455 NYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCF 514
NYSG +VSL DIC+KPLG +CATQSILQYF+MD NFDN GG+EH EYCFQHYTS E+C
Sbjct: 478 NYSGAMVSLPDICMKPLGTECATQSILQYFKMDRSNFDNLGGIEHVEYCFQHYTSAESCL 537
Query: 515 SAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
SAFKAPL+P TALGGFSGNNYSEASAFI+TYPVNNA+ K G+ + KA+AWEKAFIQL K
Sbjct: 538 SAFKAPLDPNTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNYSKKAVAWEKAFIQLVK 596
>D7MEY0_ARALL (tr|D7MEY0) Patched family protein OS=Arabidopsis lyrata subsp.
lyrata GN=ARALYDRAFT_490595 PE=4 SV=1
Length = 1064
Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 334/538 (62%), Positives = 403/538 (74%), Gaps = 25/538 (4%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG R+DGKVLNCPY SPS+KP DL SAKIQSLCPTITG VCCTE Q Q
Sbjct: 1 MYDICGHRTDGKVLNCPYASPSIKPDDLFSAKIQSLCPTITGKVCCTETQFDTLRSQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
AVP LVGCPACLRNFLNLFCELSCSPNQSLFINVTS+++V GN+TVDGID ++T+TFGEG
Sbjct: 61 AVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVAEVSGNLTVDGIDYHITDTFGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY +CK+VKFGTMNTRAI+FVG GA N++EWF F+GQK PPGFPGSPY+I+FK++ +SS
Sbjct: 121 LYESCKEVKFGTMNTRAINFVGGGAQNFREWFTFIGQKAPPGFPGSPYAINFKSSTPESS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLA 275
M MN SVYSC +S I++G LKVRC++LS+
Sbjct: 181 AMVPMNLSVYSCACSS---------------PEPLPPHEEDSCSIRIGPLKVRCIELSMV 225
Query: 276 VLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEV 335
++YI+LV FGW G S+EPLL N +L + QR
Sbjct: 226 LVYILLVSCFFGWAALNRRRDITQPGDSSEPLLHPVEEDGINSETKENILGVKVQRH--A 283
Query: 336 QYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPES 395
Q S +Q +++ FYR+YG W AR P+++L S+AIV+ L GL F VETRPEKLWVGPES
Sbjct: 284 QLSPVQRYMAKFYRSYGSWIARNPSLILFMSVAIVLALSSGLYNFKVETRPEKLWVGPES 343
Query: 396 KAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRAN 455
KAAEEK++FD+HL+PFYRIEQLI+AT+P+ + G+ PSIVTD+NI LLF+IQ+KVD+IR N
Sbjct: 344 KAAEEKKYFDTHLSPFYRIEQLILATVPDPKSGRAPSIVTDENILLLFDIQQKVDQIRGN 403
Query: 456 YSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFS 515
YSG VSL DICLKPLGEDCATQSILQYF+MD FD+YGGVEHAEYCFQHYTS E C S
Sbjct: 404 YSGSEVSLPDICLKPLGEDCATQSILQYFKMDSGTFDDYGGVEHAEYCFQHYTSAEMCLS 463
Query: 516 AFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
AF+AP++P+ LGGFSGNNYSEA+AF++TYPVNN + +EN +A+AWEK+FIQLAK
Sbjct: 464 AFQAPVDPSAVLGGFSGNNYSEATAFVVTYPVNNVIGDSSNENARAVAWEKSFIQLAK 521
>B9H5I2_POPTR (tr|B9H5I2) Cholesterol transport protein OS=Populus trichocarpa
GN=POPTRDRAFT_818865 PE=4 SV=1
Length = 1274
Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 338/561 (60%), Positives = 406/561 (72%), Gaps = 23/561 (4%)
Query: 27 LTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN 86
LT +SR HS EYCAMYDICG R DGKVLNCPY SPSVKP DLLS KIQSLCPTITGN
Sbjct: 22 LTRNAVSRERHSEEYCAMYDICGAREDGKVLNCPYGSPSVKPDDLLSQKIQSLCPTITGN 81
Query: 87 VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC+E Q QA+P LVGCPACLRNFLNLFCEL+CSP+QS FINVT+ ++V GN
Sbjct: 82 VCCSEAQFDTLRSQVQQAIPFLVGCPACLRNFLNLFCELTCSPHQSTFINVTTTAKVKGN 141
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
+TV GID Y ++ FGEGLY +CKDVKFGTMNTRA++F+GAGA N+ EW+AF+G++ P
Sbjct: 142 LTVSGIDFYASDAFGEGLYESCKDVKFGTMNTRALNFIGAGAQNFTEWYAFIGRRAPLDV 201
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
PGSPY++ FK T +SS ++ MN S YSC D SLG
Sbjct: 202 PGSPYAMTFKPTAPESSGIKPMNVSTYSCGDISLGCSCGDCPQSPVCANTAPPPHH---- 257
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPL--LVSEG---- 312
+ GS +CVD +L +LYI+L+ + GW S PL + G
Sbjct: 258 --EGGSCAAKCVDFALTILYIILISMFLGW-GLFHRKRERNQTSRMNPLSDIKDSGEVIR 314
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
+ NLP +++ PQ + VQ S +Q ++S FYR YG W AR P +VL SLA+++L
Sbjct: 315 KKDENLP--AQMVEDSPQTGSRVQLSIVQGYMSKFYRRYGTWVARNPILVLSLSLAVILL 372
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
LC GL+RF VETRPEKLWVGP SK AEEK FFD+HLAPFYRIEQLI+AT+P++ K PS
Sbjct: 373 LCVGLIRFKVETRPEKLWVGPGSKVAEEKRFFDTHLAPFYRIEQLILATVPDAGAQKLPS 432
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
IVT+DNI+LLFEIQ+KVD IRANYSG +VSL+DIC+KPL +DCATQS+LQYFQMDP N +
Sbjct: 433 IVTEDNIKLLFEIQKKVDGIRANYSGSMVSLTDICMKPLDKDCATQSVLQYFQMDPQNLE 492
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALT 552
NYGGVEH YC QHYTS +TC SAFKAPL+P+T+LGGFSGNNYSEASAFI+TYPVNN +
Sbjct: 493 NYGGVEHVNYCLQHYTSADTCRSAFKAPLDPSTSLGGFSGNNYSEASAFIVTYPVNNVID 552
Query: 553 KVGDENGKAIAWEKAFIQLAK 573
K G+E KA+AWEKAFIQL K
Sbjct: 553 KEGNETDKAVAWEKAFIQLVK 573
>I1K7C8_SOYBN (tr|I1K7C8) Uncharacterized protein OS=Glycine max PE=4 SV=2
Length = 1291
Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 331/554 (59%), Positives = 408/554 (73%), Gaps = 17/554 (3%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HS +YCAMYDICG RSDGKV+NCP+ SP+VKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 45 HSEDYCAMYDICGTRSDGKVVNCPHGSPAVKPDDLLSSKIQSLCPTITGNVCCTEAQFET 104
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P LVGCPACLRNFLNLFCEL+CSPNQSLFINVTS+ V GN TV GID +V
Sbjct: 105 LRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVDNVSGNSTVGGIDYFV 164
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FGEGLY +CK+VKFGTMN+RA+ F+GAGA N+K+WFAF+G+K P GSPY+I F+
Sbjct: 165 TDAFGEGLYESCKEVKFGTMNSRALQFIGAGAQNFKDWFAFIGRKAAPHGLGSPYAITFR 224
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
+SS M+ MN S YSC D SLG +K+G+L V
Sbjct: 225 PNATESSDMKPMNVSTYSCGDISLGCSCGDCPSSSVCSSSASTTTNKKDSCSVKIGTLMV 284
Query: 268 RCVDLSLAVLYIVLVFVLFGW-IXXXXXXXXXXXGSSAEPLLVSEGRSFT-------NLP 319
+CVDL LAVLY++L+ V GW + + + ++S+G ++ N+P
Sbjct: 285 KCVDLILAVLYVILICVFLGWGLYHRIRERKPTYRTKSMSNVISDGALYSHSREKDENVP 344
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
++ Q +N V+ S +Q +++NFYR YG + AR P +VL SSLAIV+LLC GL++
Sbjct: 345 MQIHMMEDAQQNRNRVRLSAVQGYMTNFYRKYGSYVARHPIMVLASSLAIVLLLCLGLIQ 404
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F VETRPEKLWVGP SKAA+EK+FFD+HLAPFYRIEQLI+AT+P++ + P IVT+DNI
Sbjct: 405 FKVETRPEKLWVGPGSKAAQEKQFFDTHLAPFYRIEQLILATVPDNVNSTSPRIVTEDNI 464
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
LFEIQ+KVD IRANYSGL VSL DIC+KPL +DCATQS+LQYF+MDP NFD+YGGVEH
Sbjct: 465 RFLFEIQKKVDAIRANYSGLTVSLQDICMKPLDKDCATQSVLQYFKMDPKNFDDYGGVEH 524
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
YCF+HY+S + C SAFKAPL+P+T LGGFSGN+YSEASAFI+TYPVNNA+ K G+
Sbjct: 525 LNYCFEHYSSADRCMSAFKAPLDPSTVLGGFSGNDYSEASAFIVTYPVNNAINKEGNGTR 584
Query: 560 KAIAWEKAFIQLAK 573
KA+AWEK FIQL K
Sbjct: 585 KAVAWEKTFIQLVK 598
>K7KHM4_SOYBN (tr|K7KHM4) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1291
Score = 687 bits (1772), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 330/554 (59%), Positives = 405/554 (73%), Gaps = 17/554 (3%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HS +YCAMYDICG RSDGKV+NCPY SP+VKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 45 HSEDYCAMYDICGTRSDGKVVNCPYGSPAVKPDDLLSSKIQSLCPTITGNVCCTEAQFET 104
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P LVGCPACLRNFLNLFCEL+CSPNQSLFINVTS+ V GN+TV GID +V
Sbjct: 105 LRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVDNVGGNLTVGGIDYFV 164
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FGEGLY +CK+VKFGTMN+RA+ F+GAGA NYK+WF+F+G+K P GSPY+I F
Sbjct: 165 TDAFGEGLYESCKEVKFGTMNSRALQFIGAGAQNYKDWFSFIGRKAAPHGLGSPYAITFW 224
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
SS M+ MN S YSC D SLG +K+G+L V
Sbjct: 225 PNATASSDMKPMNVSTYSCGDISLGCSCGDCPSSSVCSNSASTTTNKKDSCSVKVGTLMV 284
Query: 268 RCVDLSLAVLYIVLVFVLFGW-IXXXXXXXXXXXGSSAEPLLVSEGRSFT-------NLP 319
+CVDLSLAVLYI+L+ V GW + + + ++S+G ++ NLP
Sbjct: 285 KCVDLSLAVLYIILICVFLGWGLYHRIRERKPTYRTKSVSNVISDGALYSHNREKDENLP 344
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
++ Q +N V+ S +Q +++NFYR YG + AR P +VL SSLAIV+LLC GL+R
Sbjct: 345 MQIHMMEDAQQNRNRVRLSAVQGYMTNFYRKYGSYVARHPIMVLASSLAIVLLLCLGLIR 404
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F VETRPEKLWVGP SKAA+EK+FFD+HLAPFYRIEQLI+AT+P+ + IV++DNI
Sbjct: 405 FKVETRPEKLWVGPGSKAAQEKQFFDTHLAPFYRIEQLILATVPDHVNSTSTRIVSEDNI 464
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
LFEIQ+KVD IRANYSGL VSL DIC+KPL +DCATQS+LQYF+MD NFD+YGG+EH
Sbjct: 465 RFLFEIQKKVDAIRANYSGLTVSLQDICMKPLDKDCATQSVLQYFKMDLKNFDDYGGIEH 524
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
YCF+HY+S + C SAFKAPL+P+T LGGFSGN+YSEASAFI+TYP+NNA+ + G+
Sbjct: 525 LNYCFEHYSSADHCMSAFKAPLDPSTVLGGFSGNDYSEASAFIVTYPINNAINEEGNGTR 584
Query: 560 KAIAWEKAFIQLAK 573
KA+AWEK FIQL K
Sbjct: 585 KAVAWEKTFIQLVK 598
>K7KHM5_SOYBN (tr|K7KHM5) Uncharacterized protein OS=Glycine max PE=4 SV=1
Length = 1244
Score = 687 bits (1772), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 330/554 (59%), Positives = 405/554 (73%), Gaps = 17/554 (3%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HS +YCAMYDICG RSDGKV+NCPY SP+VKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 45 HSEDYCAMYDICGTRSDGKVVNCPYGSPAVKPDDLLSSKIQSLCPTITGNVCCTEAQFET 104
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P LVGCPACLRNFLNLFCEL+CSPNQSLFINVTS+ V GN+TV GID +V
Sbjct: 105 LRTQVQQAIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVDNVGGNLTVGGIDYFV 164
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FGEGLY +CK+VKFGTMN+RA+ F+GAGA NYK+WF+F+G+K P GSPY+I F
Sbjct: 165 TDAFGEGLYESCKEVKFGTMNSRALQFIGAGAQNYKDWFSFIGRKAAPHGLGSPYAITFW 224
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
SS M+ MN S YSC D SLG +K+G+L V
Sbjct: 225 PNATASSDMKPMNVSTYSCGDISLGCSCGDCPSSSVCSNSASTTTNKKDSCSVKVGTLMV 284
Query: 268 RCVDLSLAVLYIVLVFVLFGW-IXXXXXXXXXXXGSSAEPLLVSEGRSFT-------NLP 319
+CVDLSLAVLYI+L+ V GW + + + ++S+G ++ NLP
Sbjct: 285 KCVDLSLAVLYIILICVFLGWGLYHRIRERKPTYRTKSVSNVISDGALYSHNREKDENLP 344
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
++ Q +N V+ S +Q +++NFYR YG + AR P +VL SSLAIV+LLC GL+R
Sbjct: 345 MQIHMMEDAQQNRNRVRLSAVQGYMTNFYRKYGSYVARHPIMVLASSLAIVLLLCLGLIR 404
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F VETRPEKLWVGP SKAA+EK+FFD+HLAPFYRIEQLI+AT+P+ + IV++DNI
Sbjct: 405 FKVETRPEKLWVGPGSKAAQEKQFFDTHLAPFYRIEQLILATVPDHVNSTSTRIVSEDNI 464
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
LFEIQ+KVD IRANYSGL VSL DIC+KPL +DCATQS+LQYF+MD NFD+YGG+EH
Sbjct: 465 RFLFEIQKKVDAIRANYSGLTVSLQDICMKPLDKDCATQSVLQYFKMDLKNFDDYGGIEH 524
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
YCF+HY+S + C SAFKAPL+P+T LGGFSGN+YSEASAFI+TYP+NNA+ + G+
Sbjct: 525 LNYCFEHYSSADHCMSAFKAPLDPSTVLGGFSGNDYSEASAFIVTYPINNAINEEGNGTR 584
Query: 560 KAIAWEKAFIQLAK 573
KA+AWEK FIQL K
Sbjct: 585 KAVAWEKTFIQLVK 598
>R0ILR5_9BRAS (tr|R0ILR5) Uncharacterized protein OS=Capsella rubella
GN=CARUB_v10008106mg PE=4 SV=1
Length = 1260
Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/550 (59%), Positives = 406/550 (73%), Gaps = 16/550 (2%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--- 94
S YCAMYDICG RSDGKVLNCP+ P++KP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 15 SAGYCAMYDICGARSDGKVLNCPFNIPAIKPDDLLSSKIQSLCPTITGNVCCTETQFDTL 74
Query: 95 -----QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVT 149
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS ++V N TVDGI Y+T
Sbjct: 75 RSQVQQAIPFVVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVKNNSTVDGIQYYIT 134
Query: 150 ETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKT 209
+ FG G+Y +CKDVKFG+ NTRA+DF+GAGA N+KEWF F+GQK PGSPY ++F
Sbjct: 135 DEFGAGMYESCKDVKFGSSNTRALDFLGAGAKNFKEWFTFIGQKAGVNVPGSPYGMEFLP 194
Query: 210 TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVR 268
T SS M MN S YSC D +LG IKMGSL+V+
Sbjct: 195 TPPVSSGMRPMNVSSYSCGDDTLGCSCGDCPSAATCSSKEEIPSQKKHSCSIKMGSLEVK 254
Query: 269 CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG-RSFTNLPK----DGE 323
CVD LA+LYIVLV + G S PL + G R+ N K +
Sbjct: 255 CVDFILAILYIVLVSLFLGG-GVLHRVRGKKMTSQMRPLSEAGGERNAVNHQKPDTIHAQ 313
Query: 324 VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
+L PQR N Q S +Q +L+NFYR YG W AR P++VLC S++IV+LLC GL+RF VE
Sbjct: 314 MLQNTPQR-NWSQLSTVQGYLANFYRKYGIWVARHPSLVLCLSVSIVLLLCVGLIRFKVE 372
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLF 443
TRP+KLWVGP S+AAEEKEFFD+HLAPFYRIEQLI+AT+P+S H K P I+TDDNI+LLF
Sbjct: 373 TRPDKLWVGPGSRAAEEKEFFDTHLAPFYRIEQLILATVPKSPHEKAPEILTDDNIKLLF 432
Query: 444 EIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYC 503
+IQ+KVD +RAN+SG +VSL+DIC+KPLGEDCATQS+LQYF+M +N++++GG++H +YC
Sbjct: 433 DIQKKVDGLRANHSGSMVSLTDICMKPLGEDCATQSVLQYFKMKLENYEDFGGIDHVKYC 492
Query: 504 FQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
F+H+TST++C SAFK PL+P TA+GGFSGNN+SEASAF+ITYPV+NA+ G++ KA+A
Sbjct: 493 FEHFTSTDSCLSAFKGPLDPATAMGGFSGNNFSEASAFLITYPVDNAVNNKGNKTDKAVA 552
Query: 564 WEKAFIQLAK 573
WEKAFIQLAK
Sbjct: 553 WEKAFIQLAK 562
>B9R8N7_RICCO (tr|B9R8N7) Hedgehog receptor, putative OS=Ricinus communis
GN=RCOM_1601160 PE=4 SV=1
Length = 1235
Score = 666 bits (1718), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 338/549 (61%), Positives = 405/549 (73%), Gaps = 23/549 (4%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG R DGKVLNCP SPSVKP +LLS KIQSLCPTITGNVCCT Q Q
Sbjct: 1 MYDICGARDDGKVLNCPRGSPSVKPDELLSQKIQSLCPTITGNVCCTAAQFATLRSQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTSIS+V N+TVDGID Y+T+ FGEG
Sbjct: 61 AIPFLVGCPACLRNFLNLFCELTCSPHQSLFINVTSISKVKNNLTVDGIDFYITDAFGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY +CKDVKFGTMNTRA++F+GAGA N++EWF F+G++ P PGSPY+I FK+ SS
Sbjct: 121 LYDSCKDVKFGTMNTRALNFIGAGAQNFREWFTFIGRRAAPNLPGSPYAITFKSAAPASS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVRCVDLSL 274
M+ MN S YSC D SLG ++ GSLK +C+D +L
Sbjct: 181 GMKPMNVSTYSCGDVSLGCSCGDCPTAPICANTAPHSQHERASCSVRFGSLKAKCIDFAL 240
Query: 275 AVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL-VSEG--------RSFTNLPKD-GEV 324
+LYI+LV +L GW S+ +PL V +G R NLP GE
Sbjct: 241 TILYILLVSMLLGW-GLFHRKRERDQTSTMKPLPNVMDGGEIHSVIRRKDENLPMQMGEY 299
Query: 325 LVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVET 384
PQ N VQ S +Q +++ FYR YG W AR P +VL S+A+V+LLC GL+RF VET
Sbjct: 300 ---SPQTGNRVQLSIVQGYMAKFYRRYGTWVARHPILVLSVSVALVLLLCLGLIRFKVET 356
Query: 385 RPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFE 444
RPEKLWVGP S+AAEEK FFDSHLAPFYRIEQLIIAT P++E GK P+IVT++NI+LLFE
Sbjct: 357 RPEKLWVGPGSRAAEEKRFFDSHLAPFYRIEQLIIATTPKAEDGKLPNIVTENNIKLLFE 416
Query: 445 IQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCF 504
+Q+KVD IRANYSG +++L+DIC+KPL +DCATQS+LQYFQMDP N++N GGV+H YCF
Sbjct: 417 LQKKVDGIRANYSGSMIALNDICMKPLDQDCATQSVLQYFQMDPQNYENSGGVDHINYCF 476
Query: 505 QHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAW 564
QHYTS +TC SAFKAPL+P+TALGGFSG+NYSEASAFI+TYPVNNA+ K G+E KA+AW
Sbjct: 477 QHYTSADTCMSAFKAPLDPSTALGGFSGSNYSEASAFIVTYPVNNAIDKEGNETKKAVAW 536
Query: 565 EKAFIQLAK 573
EKAFIQL K
Sbjct: 537 EKAFIQLVK 545
>M4EZY9_BRARP (tr|M4EZY9) Uncharacterized protein OS=Brassica rapa subsp.
pekinensis GN=Bra034382 PE=4 SV=1
Length = 1257
Score = 664 bits (1714), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 325/550 (59%), Positives = 404/550 (73%), Gaps = 17/550 (3%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
S YCAMYDICG RSDGK+LNCP+ P+VKP DLLS+KIQSLCPTITG+VCCTE Q
Sbjct: 14 QSAGYCAMYDICGARSDGKLLNCPFNIPAVKPDDLLSSKIQSLCPTITGDVCCTETQFDT 73
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS +++ N TVDGI+ Y+
Sbjct: 74 LRSQVQQAIPFIVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKIKNNSTVDGIEYYI 133
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T++FGEGLY +CK+VKFG+ N+RA+DF+GAGA N+KEWFAF+GQK PGSPY I F
Sbjct: 134 TDSFGEGLYESCKNVKFGSSNSRALDFLGAGAKNFKEWFAFIGQKAGVNLPGSPYGIKFS 193
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKV 267
+ SS M+ MN S YSC+D +LG IK+GSL+
Sbjct: 194 PSPPVSSGMKPMNVSTYSCSDDTLGCSCGDCPSAAACSSTAAPPTQKRHACSIKIGSLEA 253
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK----DGE 323
+CVD LA+LY VLV + G +E S RS N K +
Sbjct: 254 KCVDFVLAILYTVLVSLFLGGGLFHRIKGKKNSSPLSE---ASRDRSSVNPQKADTIHAQ 310
Query: 324 VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
+L PQR N Q S +Q +L+NFYR YG W AR PT+VLC S++ V+LLC GL++F VE
Sbjct: 311 MLQNTPQR-NWAQLSAVQGFLANFYRKYGIWVARNPTLVLCLSVSAVLLLCVGLVQFKVE 369
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLF 443
T+P+KLWVG S+AAEEK+FFD+HLAPFYR+EQLIIAT+P+S H K P I+TDDNI+LLF
Sbjct: 370 TKPDKLWVGKGSRAAEEKQFFDTHLAPFYRLEQLIIATVPKSPHDKAPEILTDDNIKLLF 429
Query: 444 EIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYC 503
+IQ+ VD +RAN+SG +VSL+DICLKPLGEDCATQS+LQYF+M P N+D++GGV+H +YC
Sbjct: 430 DIQKMVDGLRANHSGSMVSLTDICLKPLGEDCATQSVLQYFKMKPGNYDDFGGVDHVKYC 489
Query: 504 FQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
F+H+TSTE+C SAFK PL+PTTALGGFSGN+YSEA AFI+TYPV+NA+ G++ KA+A
Sbjct: 490 FEHFTSTESCLSAFKGPLDPTTALGGFSGNSYSEAYAFIVTYPVDNAVDNEGNKTEKAVA 549
Query: 564 WEKAFIQLAK 573
WEKAFIQLAK
Sbjct: 550 WEKAFIQLAK 559
>D7KMU0_ARALL (tr|D7KMU0) Predicted protein OS=Arabidopsis lyrata subsp. lyrata
GN=ARALYDRAFT_681453 PE=4 SV=1
Length = 1261
Score = 663 bits (1710), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 327/551 (59%), Positives = 404/551 (73%), Gaps = 16/551 (2%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
S YCAMYDICG RSDGKVLNCP+ P+VKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 14 QSAGYCAMYDICGARSDGKVLNCPFNIPAVKPDDLLSSKIQSLCPTITGNVCCTETQFDT 73
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS ++V N TVDGI Y+
Sbjct: 74 LRSQVQQAIPFIVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVKNNSTVDGIQYYI 133
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FG G+Y +CK+VKFG+ N+RA+DF+GAGA N+KEWFAF+GQK PGSPY I F
Sbjct: 134 TDDFGAGMYESCKNVKFGSSNSRALDFLGAGAKNFKEWFAFIGQKAGVNVPGSPYGIAFL 193
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX-XXXXXXXXIKMGSLKV 267
T SS M MN S YSC D SLG IK+GSL+
Sbjct: 194 PTPPVSSGMRPMNVSTYSCGDESLGCSCGDCPSAATCSSKAEVPTQKKHSCSIKIGSLEA 253
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG-RSFTNLPK----DG 322
+CVD LA++YIVLV + G S P + G ++ NL K
Sbjct: 254 KCVDFILAIVYIVLVSLFLGG-GLLHRVRGKKKTSQMRPSSEAGGEQNSANLQKPDTIHA 312
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNV 382
++L PQR N Q S +Q L+NFYR YG W AR PT+VLC S+++V+LLC GL+RF V
Sbjct: 313 QMLQNTPQR-NWGQLSTVQGHLANFYRKYGIWVARHPTLVLCLSVSVVLLLCVGLIRFKV 371
Query: 383 ETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELL 442
ETRP+KLWVG S+AA+EK+FFD+HLAPFYRIEQLIIAT+ +S H K P I+TDDNI+LL
Sbjct: 372 ETRPDKLWVGSGSRAAQEKQFFDTHLAPFYRIEQLIIATVQKSSHEKAPEILTDDNIKLL 431
Query: 443 FEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEY 502
F+IQ+KVD +RAN+SG +VSL+DIC+KPLGEDCATQS+LQYF+M P+N+D++GGV+H +Y
Sbjct: 432 FDIQKKVDGLRANHSGSMVSLTDICMKPLGEDCATQSVLQYFKMKPENYDDFGGVDHVKY 491
Query: 503 CFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAI 562
CF+H+TST++C SAFK PL+PTTALGGFSGN++SEASAF++TYPV+NA+ G++ KA+
Sbjct: 492 CFEHFTSTDSCLSAFKGPLDPTTALGGFSGNSFSEASAFLVTYPVDNAVDNKGNKTEKAV 551
Query: 563 AWEKAFIQLAK 573
AWEKAFIQLAK
Sbjct: 552 AWEKAFIQLAK 562
>M5WD18_PRUPE (tr|M5WD18) Uncharacterized protein OS=Prunus persica
GN=PRUPE_ppa000374mg PE=4 SV=1
Length = 1231
Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/554 (59%), Positives = 411/554 (74%), Gaps = 33/554 (5%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MY ICG+RSDGK LNCP+ SPSVKP DLLS+K+QSLCPTITGNVCCTE Q Q
Sbjct: 1 MYGICGKRSDGKYLNCPFGSPSVKPDDLLSSKVQSLCPTITGNVCCTETQFDTLRSQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P LVGCPACLRNFLNLFCEL+CSP+QSLFINVTS+++V+ N+TVDGID Y+T+ +GEG
Sbjct: 61 AIPFLVGCPACLRNFLNLFCELTCSPSQSLFINVTSVAKVNNNLTVDGIDFYITDAYGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY +CKDVKFGTMN+RA++F+GAGA N+KEWF F+G++ P PGSPY+I F +++ +SS
Sbjct: 121 LYDSCKDVKFGTMNSRAMEFIGAGAKNFKEWFTFIGRQAPSNVPGSPYAIRFSSSVTESS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVRCVDLSL 274
M+ MN S YSC D SLG +++GS+K +C+DL++
Sbjct: 181 AMKPMNVSTYSCGDNSLGCSCGDCPSSTVCSNTVSPVSQKGGSCSVRIGSVKAKCIDLAV 240
Query: 275 AVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVID------ 328
A+LYIVLV V FGW A P S + N+ D EV I
Sbjct: 241 AILYIVLVSVFFGW-------GLFRRTRKANP--ASMTNPWWNVMDDSEVHSISREKNEN 291
Query: 329 ---------PQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
P +N VQ S +Q ++S F+R YG W AR P IVLCSSLA+V+LLC GL+R
Sbjct: 292 PPMQVFEDAPHIRNSVQLSIVQGYMSRFFRRYGTWVARNPVIVLCSSLALVLLLCLGLIR 351
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F VETRPEKLWVGP SKAAEEK FFDSHLAPFYRIEQLI+AT+PE +HG PSIVT++NI
Sbjct: 352 FKVETRPEKLWVGPGSKAAEEKNFFDSHLAPFYRIEQLILATIPEVKHGSSPSIVTEENI 411
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
+LLFEIQ+KVD I+ANYSG ++SL+DIC+KP+ +DCATQS+LQYF+M+P N+D+YGGVEH
Sbjct: 412 KLLFEIQKKVDGIKANYSGSVISLADICMKPMDKDCATQSVLQYFKMNPANYDDYGGVEH 471
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
+YCF+HY+S + C SAFK PL+P+TALGGFSG NYSEA+AF++TYPVNNA++K +E
Sbjct: 472 LKYCFEHYSSADKCMSAFKGPLDPSTALGGFSGKNYSEATAFLVTYPVNNAISKEENETE 531
Query: 560 KAIAWEKAFIQLAK 573
+A+ WEKAFI+LAK
Sbjct: 532 RAVTWEKAFIKLAK 545
>F4I9G5_ARATH (tr|F4I9G5) Patched family protein OS=Arabidopsis thaliana
GN=AT1G42470 PE=4 SV=1
Length = 1272
Score = 660 bits (1704), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 328/551 (59%), Positives = 398/551 (72%), Gaps = 15/551 (2%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
S YCAMYDICG RSDGKVLNCP+ PSVKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 14 QSAGYCAMYDICGARSDGKVLNCPFNIPSVKPDDLLSSKIQSLCPTITGNVCCTETQFDT 73
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS ++V N TVDGI Y+
Sbjct: 74 LRSQVQQAIPFIVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVKNNSTVDGIQYYI 133
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FG G+Y +CK+VKFG+ N+RA+DF+GAGA N+KEWF F+GQK PGSPY I F
Sbjct: 134 TDDFGAGMYESCKNVKFGSSNSRALDFLGAGAKNFKEWFTFIGQKAGVNLPGSPYGIAFL 193
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX-XXXXXXXXIKMGSLKV 267
T SS M MN S+YSC D SLG IK+GSL+V
Sbjct: 194 PTPPVSSGMRPMNVSIYSCGDESLGCSCGDCPSAATCSSKAEVPTQKKHSCSIKIGSLEV 253
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK----DGE 323
+CVD LA+LYIVLV + G S R+ N K +
Sbjct: 254 KCVDFILAILYIVLVSLFLGGGLLHPVRGKKKTSQMGTLSEASGERNSVNQQKPDTIQSQ 313
Query: 324 VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
+L PQR N Q S +Q L+NFY YG W AR PT+VLC S+++V+LLC GL+RF VE
Sbjct: 314 MLQNTPQR-NWGQLSTVQGHLANFYGKYGIWVARHPTLVLCLSVSVVLLLCVGLIRFKVE 372
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLF 443
TRP+KLWVG S+AAEEK+FFD+HLAPFYRIEQLIIAT+ S H K P I+TDDNI+LLF
Sbjct: 373 TRPDKLWVGSGSRAAEEKQFFDTHLAPFYRIEQLIIATVQTSSHEKAPEILTDDNIKLLF 432
Query: 444 EIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSIL-QYFQMDPDNFDNYGGVEHAEY 502
+IQ+KVD +RAN+SG +VSL+DIC+KPLGEDCATQS+L QYF+M P+N+D+YGGV+H +Y
Sbjct: 433 DIQKKVDGLRANHSGSMVSLTDICMKPLGEDCATQSVLQQYFKMKPENYDDYGGVDHVKY 492
Query: 503 CFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAI 562
CF+H+TSTE+C SAFK PL+PTTALGGFSGN++SEASAF++TYPV+N + G++ KA+
Sbjct: 493 CFEHFTSTESCLSAFKGPLDPTTALGGFSGNSFSEASAFLVTYPVDNFVDNKGNKTEKAV 552
Query: 563 AWEKAFIQLAK 573
AWEKAFIQLAK
Sbjct: 553 AWEKAFIQLAK 563
>A5APM6_VITVI (tr|A5APM6) Putative uncharacterized protein OS=Vitis vinifera
GN=VITISV_009389 PE=4 SV=1
Length = 1050
Score = 652 bits (1682), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 319/546 (58%), Positives = 395/546 (72%), Gaps = 44/546 (8%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG+RSDGKVLNCPY SPSVKP DLLS+KIQS+CPTI+GNVCCTE Q Q
Sbjct: 1 MYDICGKRSDGKVLNCPYGSPSVKPDDLLSSKIQSMCPTISGNVCCTEAQFDTLRTQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P LVGCPACLRNFLNLFCEL+CSPNQSLFINVTS+S+V+ N+TVDGI+ +T+ FGEG
Sbjct: 61 AIPFLVGCPACLRNFLNLFCELTCSPNQSLFINVTSVSKVNNNLTVDGIEFIITDAFGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY++CKDVKFGTMNTRAIDF+GAGA +KEWFAF+G + P PGSPY+I+F+ +I +SS
Sbjct: 121 LYNSCKDVKFGTMNTRAIDFIGAGAKTFKEWFAFIGTRAAPSVPGSPYAINFQPSIAESS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSL 274
M+ MN S YSC D SLG +++GSLK +C++ SL
Sbjct: 181 GMKPMNVSTYSCGDNSLGCSCGDCPSASVCSGYAPPSLHKEGSCSVRIGSLKAKCIEFSL 240
Query: 275 AVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF--TNLPKD----GEVLVID 328
A+LYI+LV + FGW L V +G N PKD ++L
Sbjct: 241 AILYIILVTIFFGWGLFHRTRERNPTPRMKPMLNVMDGSELHSMNRPKDDNLSSQMLEDV 300
Query: 329 PQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEK 388
PQ +N VQ S +Q ++SNFYR YG W AR PTI+LCSSLAIV++LC GL+RF VETRPEK
Sbjct: 301 PQIRNGVQLSIVQGYMSNFYRRYGTWVARHPTIMLCSSLAIVLVLCLGLIRFKVETRPEK 360
Query: 389 LWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEK 448
L++AT+P++ +G PSIVT++NI+LLFEIQ+K
Sbjct: 361 ----------------------------LVLATIPDA-NGISPSIVTENNIKLLFEIQKK 391
Query: 449 VDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYT 508
VD +RAN+SG ++SL+DIC+KPLG+DCATQS+LQYF+MD N+D+YGGV+H EYCFQHYT
Sbjct: 392 VDGLRANFSGSMISLTDICMKPLGQDCATQSVLQYFKMDSRNYDDYGGVQHVEYCFQHYT 451
Query: 509 STETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
S +TC SAFKAPL+P+TALGGFSGNNYSEASAFI+TYPVNNA+ K G+E GKA+AWEKAF
Sbjct: 452 SADTCMSAFKAPLDPSTALGGFSGNNYSEASAFIVTYPVNNAIDKEGNETGKAVAWEKAF 511
Query: 569 IQLAKV 574
IQ+ K+
Sbjct: 512 IQIVKI 517
>M4D678_BRARP (tr|M4D678) Uncharacterized protein OS=Brassica rapa subsp.
pekinensis GN=Bra011986 PE=4 SV=1
Length = 1255
Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 321/546 (58%), Positives = 391/546 (71%), Gaps = 16/546 (2%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--- 94
S YCAMYDICG R+DGKVLNCPY P+VKP DL S+KIQSLCPTITGNVCCTE Q
Sbjct: 22 SAGYCAMYDICGARTDGKVLNCPYNIPAVKPDDLFSSKIQSLCPTITGNVCCTETQFDTL 81
Query: 95 -----QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVT 149
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS +++ N TVDGI Y+T
Sbjct: 82 RSQVQQAIPFVVGCPACLRNFLNLFCELTCSPDQSLFINVTSTAKIKNNSTVDGIQYYIT 141
Query: 150 ETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKT 209
+ FGEG+Y +CK+VKFG+ N+ A+DF+G GA N+KEWF F+GQK PGSPY I F
Sbjct: 142 DAFGEGMYESCKNVKFGSSNSLAVDFLGGGAKNFKEWFTFIGQKAGVNMPGSPYGIKFLP 201
Query: 210 TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVR 268
SS M+ MN S YSC+D +LG IK+GSL+ +
Sbjct: 202 MPPASSGMKPMNVSSYSCSDDTLGCSCGDCPSAAACSSTSAPPAQKQRSCSIKIGSLEAK 261
Query: 269 CVDLSLAVLYIVLV-FVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVI 327
CVD LA+LYIVLV L G + SS+EP E S ++L
Sbjct: 262 CVDFVLAILYIVLVSLFLGGGLIHRIKGKKKSSPSSSEPR--GEQSSVKPDTIHAQMLQN 319
Query: 328 DPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPE 387
PQR N Q S +Q +L+ FY YG W AR P +VL S+ +V+LLC GL+RF VETRP+
Sbjct: 320 TPQR-NWAQLSTVQGYLARFYSKYGIWVARHPALVLIVSVFLVLLLCVGLIRFKVETRPD 378
Query: 388 KLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQE 447
KLWVG S+AA+EK FFD+HLAPFYRIEQLIIAT P+S P I+TDDNI+LLF+IQ+
Sbjct: 379 KLWVGAGSRAADEKRFFDTHLAPFYRIEQLIIATAPKSSQ---PEILTDDNIKLLFDIQK 435
Query: 448 KVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHY 507
KVD +RAN+SG +VSL+DIC+KPLGEDCATQS+LQYFQM P N+D +GGVEH +YCF+H+
Sbjct: 436 KVDGLRANHSGSMVSLTDICMKPLGEDCATQSLLQYFQMIPKNYDEFGGVEHVKYCFEHF 495
Query: 508 TSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKA 567
TS+E+C SAFK PL+PTTALGGFSGN+YSEASAFI+TYPV+NA+ G+ +A+AWEKA
Sbjct: 496 TSSESCLSAFKGPLDPTTALGGFSGNSYSEASAFIVTYPVDNAVDNKGNRTVRAVAWEKA 555
Query: 568 FIQLAK 573
FIQLAK
Sbjct: 556 FIQLAK 561
>Q9SVF0_ARATH (tr|Q9SVF0) Putative uncharacterized protein AT4g38350
OS=Arabidopsis thaliana GN=F22I13.120 PE=4 SV=1
Length = 1055
Score = 611 bits (1575), Expect = e-172, Method: Compositional matrix adjust.
Identities = 306/562 (54%), Positives = 377/562 (67%), Gaps = 83/562 (14%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MYDICG RSDGKVLNCPY SPS++P +L SAKIQSLCPTI+GNVCCTE Q Q
Sbjct: 1 MYDICGHRSDGKVLNCPYASPSIQPDELFSAKIQSLCPTISGNVCCTETQFDTLRSQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
AVP LVGCPACLRNFLNLFCELSCSPNQSLFINVTS+++V GN+TVDGID ++T+TFGEG
Sbjct: 61 AVPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSVAEVSGNLTVDGIDYHITDTFGEG 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
LY +CK+VKFGTMNTRAI+FVG GA N++EWF F+GQK P GFPGSPY+I+FK++I +SS
Sbjct: 121 LYESCKEVKFGTMNTRAINFVGGGAKNFREWFTFIGQKAPSGFPGSPYAINFKSSIPESS 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLA 275
M MN SVYSC +S I++G LKVRC++LS+A
Sbjct: 181 AMVPMNVSVYSCACSS---------------PEPLPPHDEDSCSIRIGPLKVRCIELSMA 225
Query: 276 VLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEV 335
++Y++LV FGW S++PLL N +L + QR
Sbjct: 226 LVYVLLVSCFFGWAGLNRRRNTTQPLDSSKPLLHPVEEDGINSEMKENILGVKVQRH--A 283
Query: 336 QYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPES 395
Q S +Q +++ FYR+YG W AR P++VL S+AIV+ LC GL F VETRPEKLWVGPES
Sbjct: 284 QLSPVQRYMAKFYRSYGSWIARNPSLVLFMSVAIVLALCSGLYNFKVETRPEKLWVGPES 343
Query: 396 KAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRAN 455
KAAEEK+FFD+HL+PFYRIEQLI+AT+P+ + G+ PSIVTD+NI LLF+IQ+K
Sbjct: 344 KAAEEKKFFDTHLSPFYRIEQLILATVPDPKSGRAPSIVTDENILLLFDIQQK------- 396
Query: 456 YSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFS 515
YF+MD FD+YGGVEHAEYCFQHYTS+ETC S
Sbjct: 397 ---------------------------YFKMDSGTFDDYGGVEHAEYCFQHYTSSETCLS 429
Query: 516 AFKAPLEPTTALGGFSGNNYSE------------------------ASAFIITYPVNNAL 551
AF+AP++P+ LGGFSGNNYSE A+AF++TYPVNN +
Sbjct: 430 AFQAPVDPSAVLGGFSGNNYSEVMVSELGCSVPFDCYSDVKRTLFQATAFVVTYPVNNVI 489
Query: 552 TKVGDENGKAIAWEKAFIQLAK 573
+EN +A+AWEK+FIQLAK
Sbjct: 490 GDSSNENARAVAWEKSFIQLAK 511
>K3Y4Q6_SETIT (tr|K3Y4Q6) Uncharacterized protein OS=Setaria italica
GN=Si009194m.g PE=4 SV=1
Length = 1272
Score = 610 bits (1572), Expect = e-172, Method: Compositional matrix adjust.
Identities = 308/582 (52%), Positives = 399/582 (68%), Gaps = 33/582 (5%)
Query: 14 LLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLS 73
++Q+ +L+ F S + SR + + YC+MY IC QRSDGKVLNC + +VKP L S
Sbjct: 1 MMQISLLA-FPISAQQSNGSRVVPAEGYCSMYGICAQRSDGKVLNCANATKAVKPDTLFS 59
Query: 74 AKIQSLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSL 125
++IQSLCPTITGNVCCT +Q QAVP LVGCPACLRNFLNLFCE+SCSPNQSL
Sbjct: 60 SRIQSLCPTITGNVCCTADQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMSCSPNQSL 119
Query: 126 FINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKE 185
FINVTS+ Q++ MTVDGID YVT +GE LY++CKDVKFGT+NTRA+DF+G GA YKE
Sbjct: 120 FINVTSVKQINSTMTVDGIDYYVTTNYGEELYNSCKDVKFGTLNTRAMDFLGGGAKTYKE 179
Query: 186 WFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXX 244
W AF+G++ P PGSPY I F++ DSS ++ +N+++YSC D SLG
Sbjct: 180 WLAFIGRQANPNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGDCPSSSVC 239
Query: 245 XXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSA 304
+KMGSLK +C+D SL V+Y+ L+ W
Sbjct: 240 TGSLLPQLNTDTSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRARGRTASSLQT 299
Query: 305 EPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQY-------------SFIQEWLSNFYRAY 351
+PL S+ +S +N ++G+ N VQ S +Q ++S F+R +
Sbjct: 300 KPLKNSDDKSDSN--QNGK------SPHNSVQVSEAASSTVKPSYPSIVQTYMSIFFRKH 351
Query: 352 GRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPF 411
G + AR P +VLC SL I +LLC GLLRF VET+PEKLWV P S+AA+EK +FDSHLAPF
Sbjct: 352 GIFVARHPLLVLCVSLLIPLLLCIGLLRFKVETQPEKLWVSPGSRAADEKNYFDSHLAPF 411
Query: 412 YRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL 471
YRIEQL++AT S PSIV D+N++LLF+IQ+KVD++RA+YSG V+L+DICLKPL
Sbjct: 412 YRIEQLVLATS-ASSGSAAPSIVNDNNMKLLFQIQKKVDDLRASYSGSTVALADICLKPL 470
Query: 472 GEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS 531
DCATQS+LQYFQ+DP +D+ G++HA++CFQHYTS ETC S F++P++P+T LGGFS
Sbjct: 471 STDCATQSVLQYFQLDPKKYDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFS 529
Query: 532 GNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
GNN++EASAF+ITYPVNN + G ENGKA+AWE+AFI L K
Sbjct: 530 GNNFTEASAFVITYPVNNKVETTGQENGKAVAWERAFINLVK 571
>M0RUG9_MUSAM (tr|M0RUG9) Uncharacterized protein OS=Musa acuminata subsp.
malaccensis PE=4 SV=1
Length = 1243
Score = 607 bits (1566), Expect = e-171, Method: Compositional matrix adjust.
Identities = 303/547 (55%), Positives = 388/547 (70%), Gaps = 21/547 (3%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MY ICGQRSDGKVL+CP + SVKP +LS+KIQSLCPTI+GNVCC+ +Q Q
Sbjct: 1 MYGICGQRSDGKVLSCPNRTHSVKPDKVLSSKIQSLCPTISGNVCCSPDQFDILRGQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN-MTVDGIDLYVTETFGE 154
+P+LVGCPACLRNFLNLFCEL CSPNQSLF NVTS+ +V+GN M VD ID YVT FGE
Sbjct: 61 VIPLLVGCPACLRNFLNLFCELVCSPNQSLFTNVTSVKKVNGNRMAVDAIDFYVTHYFGE 120
Query: 155 GLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDS 214
L+++CKDVKFGTMNTRA+DF+GAGA NY EWFA+LG + PGSPY+I F++ DS
Sbjct: 121 QLFNSCKDVKFGTMNTRAMDFIGAGAKNYPEWFAYLGHQANSNEPGSPYAITFRSKSNDS 180
Query: 215 SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX-XXXXXXXIKMGSLKVRCVDLS 273
S M MN + YSC D+SLG IK+ SLKV+C+DLS
Sbjct: 181 SGMMPMNVTAYSCVDSSLGCSCGDCPSSSVCFDSLPPAPHVKQFCSIKIVSLKVKCLDLS 240
Query: 274 LAVLYIVLV--FVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQR 331
LA+ Y+ L+ F+L+G++ +P + S N + E+L I
Sbjct: 241 LAIGYLFLISAFLLWGFVYRKERTDSL----RTKPSINVNEESKLNSDEKQEILCISQIS 296
Query: 332 QN----EVQYSFIQEWLSNFYR-AYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRP 386
+ + Q Q ++S+F+R YG + ++ PT+VLC SLA+ +LLC GL+ F +ETRP
Sbjct: 297 EAPPVVKAQQPVAQRYMSDFFRWKYGSFVSKHPTLVLCLSLAVPLLLCLGLIHFEMETRP 356
Query: 387 EKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQ 446
EKLWVGP SK A+EK+FFDS L PFYRIEQLI+A++ +S + PSIVTD N++LLFE+Q
Sbjct: 357 EKLWVGPGSKTAKEKQFFDSTLGPFYRIEQLILASILDSNGERAPSIVTDKNLKLLFELQ 416
Query: 447 EKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQH 506
+KVD +RANYSG +VSL+DICLKPLG +CATQS+LQYF+MDP N+D YGG++H +YCFQH
Sbjct: 417 KKVDGLRANYSGSMVSLTDICLKPLGRNCATQSVLQYFKMDPQNYDAYGGLDHVQYCFQH 476
Query: 507 YTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEK 566
++S E C S F+APL+P+TALGGFSG+NYSEA AF+ITYPVNN L K E K++AWEK
Sbjct: 477 FSSAEKCLSEFQAPLDPSTALGGFSGSNYSEALAFVITYPVNNELDKKSTEYAKSVAWEK 536
Query: 567 AFIQLAK 573
AF++L +
Sbjct: 537 AFVRLMQ 543
>Q9SHN9_ARATH (tr|Q9SHN9) F7F22.1 OS=Arabidopsis thaliana PE=4 SV=1
Length = 1275
Score = 603 bits (1555), Expect = e-170, Method: Compositional matrix adjust.
Identities = 308/552 (55%), Positives = 376/552 (68%), Gaps = 25/552 (4%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
S YCAMYDICG RSDGKVLNCP+ PSVKP DLLS+KIQSLCPTITGNVCCTE Q
Sbjct: 14 QSAGYCAMYDICGARSDGKVLNCPFNIPSVKPDDLLSSKIQSLCPTITGNVCCTETQFDT 73
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYV 148
QA+P +VGCPACLRNFLNLFCEL+CSP+QSLFINVTS ++V N TVDGI Y+
Sbjct: 74 LRSQVQQAIPFIVGCPACLRNFLNLFCELTCSPDQSLFINVTSTTKVKNNSTVDGIQYYI 133
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
T+ FG G+Y +CK+VKFG+ N+RA+DF+GAGA N+KEWF F+GQK PGSPY I F
Sbjct: 134 TDDFGAGMYESCKNVKFGSSNSRALDFLGAGAKNFKEWFTFIGQKAGVNLPGSPYGIAFL 193
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
T SS M MN S+YSC D SLG IK+GSL+V
Sbjct: 194 PTPPVSSGMRPMNVSIYSCGDESLGCSCGDCPSAATCSSKAEVPTQKKHSCSIKIGSLEV 253
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK----DGE 323
+CVD LA+LYIVLV + G S R+ N K +
Sbjct: 254 KCVDFILAILYIVLVSLFLGGGLLHPVRGKKKTSQMGTLSEASGERNSVNQQKPDTIQSQ 313
Query: 324 VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
+L PQR N Q S +Q L+NFY YG W AR PT+VLC S+++V+LLC GL+RF VE
Sbjct: 314 MLQNTPQR-NWGQLSTVQGHLANFYGKYGIWVARHPTLVLCLSVSVVLLLCVGLIRFKVE 372
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLF 443
TRP+KLWVG S+AAEEK+FFD+HLAPFYRIEQLIIAT+ S H K P I+TDDNI+LLF
Sbjct: 373 TRPDKLWVGSGSRAAEEKQFFDTHLAPFYRIEQLIIATVQTSSHEKAPEILTDDNIKLLF 432
Query: 444 EIQEKVDEIRANYSG--LLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAE 501
+IQ+KV ++ +N S V + C K YF+M P+N+D+YGGV+H +
Sbjct: 433 DIQKKVSQLFSNPSNHPYNVFMYRTCKKLFN---------MYFKMKPENYDDYGGVDHVK 483
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
YCF+H+TSTE+C SAFK PL+PTTALGGFSGN++SEASAF++TYPV+N + G++ KA
Sbjct: 484 YCFEHFTSTESCLSAFKGPLDPTTALGGFSGNSFSEASAFLVTYPVDNFVDNKGNKTEKA 543
Query: 562 IAWEKAFIQLAK 573
+AWEKAFIQLAK
Sbjct: 544 VAWEKAFIQLAK 555
>C5YE00_SORBI (tr|C5YE00) Putative uncharacterized protein Sb06g025390 OS=Sorghum
bicolor GN=Sb06g025390 PE=4 SV=1
Length = 1232
Score = 579 bits (1493), Expect = e-163, Method: Compositional matrix adjust.
Identities = 301/573 (52%), Positives = 389/573 (67%), Gaps = 42/573 (7%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L S++IQSLCPTITG+VCCT +
Sbjct: 38 SRVVPAEGYCSMYGICAQRSDGKVLNCANATKAVKPDTLFSSRIQSLCPTITGDVCCTVD 97
Query: 93 QL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI---------SQV 135
Q QAVP LVGCPACLRNFLNLFCE+SCSPNQSLFINVTS+ SQ+
Sbjct: 98 QFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVHFCLFFSQI 157
Query: 136 DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVP 195
+ MTVDG+D YVT +GE LY +CKDVKFGT+NTRA+DF+GAGA YK+W AF+G++
Sbjct: 158 NSTMTVDGLDYYVTTNYGEELYDSCKDVKFGTLNTRAMDFIGAGAKTYKDWLAFIGRQAN 217
Query: 196 PGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXX 254
PGSPY I F++ DSS ++ +N+++YSC D SLG
Sbjct: 218 SNEPGSPYLITFRSDFSDSSGVKPLNSTIYSCGDPSLGCSCGDCPSSSECTGSLLPQLNT 277
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+KMGSLK +C+D SL V+Y+ L+ W G + PL S+ +S
Sbjct: 278 ETSCSVKMGSLKAKCLDFSLVVIYLALLCAFLLWGLLHRTRGRTAFGQT-RPLRNSDNKS 336
Query: 315 FTNLPKDGEVLVIDPQRQNEVQY-------------SFIQEWLSNFYRAYGRWAARRPTI 361
+N K+G+ N VQ S +Q ++S F+R +G + AR P +
Sbjct: 337 DSN--KNGK------SPHNSVQVPEAASSTVKPSNPSIVQAYMSIFFRKHGIFVARHPLL 388
Query: 362 VLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT 421
VLC SL + +LLC GL RF VETRPEKLWV P S+AA+EK +FDSHLAPFYRIEQL++AT
Sbjct: 389 VLCVSLLVPVLLCIGLFRFKVETRPEKLWVSPGSQAADEKNYFDSHLAPFYRIEQLVLAT 448
Query: 422 LPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSIL 481
S + PSIV D+N++LLF++Q+KVD++R NYSG V+L+DICLKPL DCATQS+L
Sbjct: 449 -SASGGSEAPSIVNDNNMKLLFDVQKKVDDLRVNYSGSTVALADICLKPLSTDCATQSVL 507
Query: 482 QYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
QYFQ+DP FD+ G++HA++CFQHYTS ETC S F++P++P+T LGGF G+N++EASAF
Sbjct: 508 QYFQLDPKKFDD-SGIDHAKFCFQHYTSEETCLSTFQSPIDPSTILGGFLGSNFTEASAF 566
Query: 542 IITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
+ITYPVNN + G ENGKA+AWE+AFI L K+
Sbjct: 567 VITYPVNNKVETTGKENGKAVAWERAFINLVKL 599
>A9SMZ7_PHYPA (tr|A9SMZ7) Predicted protein OS=Physcomitrella patens subsp.
patens GN=PHYPADRAFT_132440 PE=4 SV=1
Length = 1170
Score = 573 bits (1478), Expect = e-161, Method: Compositional matrix adjust.
Identities = 285/556 (51%), Positives = 374/556 (67%), Gaps = 24/556 (4%)
Query: 34 RSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQ 93
S H + CAMYD+CG RSDGK LNCP P+P V P + S KIQSLCPTITG+VCCT Q
Sbjct: 10 ESKHGGKMCAMYDLCGSRSDGKELNCPDPTPVVTPDEAFSLKIQSLCPTITGDVCCTPTQ 69
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
QAVP L GCPACLRNFLNLFCEL+CSP+Q LFINVT++++V N TV +D
Sbjct: 70 FGLLRAQVQQAVPFLTGCPACLRNFLNLFCELACSPDQGLFINVTAVNEVRSNRTVAAVD 129
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
L+VTE +G+ +Y +CKDVKF MNTRA+DF+G GA NY EWF F+G + P PGSP++I
Sbjct: 130 LFVTEEYGQRIYDSCKDVKFAAMNTRAMDFIGGGARNYTEWFTFMGHEAGPYEPGSPFAI 189
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX-XXXXXXIKMGS 264
+F+T + + + + +N+SV +C D SL +++
Sbjct: 190 NFRTDVKEGTSVVPINSSVSACFDPSLACSCGDCPAASTCAEPNPPAPPQNRGCFVRIVG 249
Query: 265 LKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK-DGE 323
L++RC+ ++ LY+ L+FV+FGW SS EPLL + S P D E
Sbjct: 250 LEIRCLTAAMIALYVCLLFVIFGWWWTYYAPEEQL--SSEEPLLQNREDSELERPDTDSE 307
Query: 324 VLVIDPQR------QNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGL 377
+L P + +N + ++++ + + R +G W A VL S+ I ++LC GL
Sbjct: 308 IL---PAQISCNCLENPLYFNYVAKCVDK-CRIHGEWVAYNVKKVLAVSILITVVLCLGL 363
Query: 378 LRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD 437
+R NVETRPEKLWV P SKAAEEKEFFDSHLAPFYRIEQ+I+AT+P ++ PS+VTD+
Sbjct: 364 IRLNVETRPEKLWVSPGSKAAEEKEFFDSHLAPFYRIEQIILATIPANKGSSAPSVVTDE 423
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
N++LLF+IQ KVD +R NYSG L+SL DICLKPLG CATQS+LQYF+MD D F +Y G
Sbjct: 424 NLQLLFDIQAKVDSLRGNYSGKLISLQDICLKPLGTPCATQSVLQYFKMDADLFLDYEGA 483
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDE 557
+HAE+CF+HY+S+E C SAF P++PTT LGGFSGNNY++A+A ++TYPV NA++ G
Sbjct: 484 DHAEFCFEHYSSSEACLSAFGGPVDPTTILGGFSGNNYTQATALVVTYPVVNAISDEG-- 541
Query: 558 NGKAIAWEKAFIQLAK 573
N AIAWEK FI+L K
Sbjct: 542 NAAAIAWEKEFIRLVK 557
>J3M0F2_ORYBR (tr|J3M0F2) Uncharacterized protein OS=Oryza brachyantha
GN=OB04G28770 PE=4 SV=1
Length = 1281
Score = 570 bits (1470), Expect = e-160, Method: Compositional matrix adjust.
Identities = 290/558 (51%), Positives = 381/558 (68%), Gaps = 16/558 (2%)
Query: 28 TAAQISRS---IHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT 84
T+AQ S + + YC+MY IC +RSDGKVLNC + +VKP L S +IQSLCPTIT
Sbjct: 30 TSAQQSNGTSRVPAEGYCSMYGICAKRSDGKVLNCVNATKAVKPDTLFSTRIQSLCPTIT 89
Query: 85 GNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
G+VCCT +Q QA+P LVGCPACLRNFLNLFCE+SCSPNQSLFINVTS+ QV+
Sbjct: 90 GDVCCTVDQFDTLHQQVQQAIPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVN 149
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPP 196
MTV+GID YVT +GE LY +CKDVKFGT+NTRA+DF+G GA NYK+WFAFLG++
Sbjct: 150 NTMTVNGIDYYVTSNYGEELYKSCKDVKFGTLNTRAMDFLGGGAKNYKDWFAFLGRQANV 209
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXX-XXXXXXXXXXXXXXXX 255
GSPY I F + I S ++ +NA++YSC D SLG
Sbjct: 210 NEIGSPYLITFPSDISGMSSVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTE 269
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
+KMGSLK +C+D SL V+Y+VL+ + W ++ + L S
Sbjct: 270 TSCSVKMGSLKAKCLDFSLVVVYLVLLGIFLFWAFLHRTRRTKPLKNAEDKLHSSNNGKI 329
Query: 316 TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+V + S IQ ++S F+R +G + A+ P +VL SL + LLC
Sbjct: 330 PG--SSAQVSEVASTPVQSAHPSVIQTYMSTFFRKHGIFVAKHPLLVLFVSLLVPTLLCI 387
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
GL+RF VE RPEKLWV S++A+EK++FDSHLAPFYRIEQL++AT ES + P+IV
Sbjct: 388 GLVRFKVEIRPEKLWVSSGSRSADEKQYFDSHLAPFYRIEQLVLAT-SESGGSEAPTIVN 446
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
D+N++LLF+IQ+K+D++RANYSG VSL+DICLKPLG DCA+QS+LQYFQ+DP +D+
Sbjct: 447 DNNMKLLFQIQKKIDDLRANYSGSTVSLADICLKPLGTDCASQSVLQYFQLDPKKYDDL- 505
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVG 555
G++HA++CFQHYTS E C S F++P++P+T LGGF+GNN+++ASAF+ITYPVNN + G
Sbjct: 506 GIDHAKFCFQHYTSEEKCLSTFQSPIDPSTILGGFAGNNFTQASAFVITYPVNNKVETTG 565
Query: 556 DENGKAIAWEKAFIQLAK 573
ENGKAIAWE+A++ L K
Sbjct: 566 QENGKAIAWERAYVNLVK 583
>Q7XUB7_ORYSJ (tr|Q7XUB7) OSJNBb0078D11.11 protein OS=Oryza sativa subsp.
japonica GN=OSJNBb0078D11.11 PE=4 SV=2
Length = 1361
Score = 529 bits (1362), Expect = e-147, Method: Compositional matrix adjust.
Identities = 285/560 (50%), Positives = 370/560 (66%), Gaps = 49/560 (8%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+IQSLCPTITG+VCCT +
Sbjct: 44 SRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVD 103
Query: 93 QL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGI 144
Q QA+P LVGCPACLRNFLNLFCE+SCSPNQSLFINVTS+ QV+ MTV+GI
Sbjct: 104 QFDTLHQQVQQAIPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVNNTMTVNGI 163
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
D YVT T+GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++ GSPY
Sbjct: 164 DYYVTSTYGEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYL 223
Query: 205 IDFKTTILDSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
I F + I S+ ++ +NA++YSC D SLG +KMG
Sbjct: 224 ITFPSDISGSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMG 283
Query: 264 SLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
SLK +C+D SL V+Y+VL+ + LFG S +PL +E + ++ +G
Sbjct: 284 SLKAKCLDFSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDKIHSS--NNG 339
Query: 323 EVLVIDPQRQ-------NEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+V Q S IQ ++S F+R +G + A+ P +VL SL + LLC
Sbjct: 340 KVPDSSAQVSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCI 399
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPSI 433
GL+RF VE RPEKLWV S+AA+EK++FDSHLAPFYRIEQL++AT S G + P+I
Sbjct: 400 GLIRFKVEIRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT---SAFGGSEAPTI 456
Query: 434 VTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDN 493
V D+N++LLF+IQ+K+D++RANYSG VSL+DICLKPLG +CATQS+L
Sbjct: 457 VNDNNMKLLFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVL------------ 504
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTK 553
QHYT+ ETC S F++P++P+T LGGF GNN++EASAF+ITYPVNN +
Sbjct: 505 -----------QHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVITYPVNNKVET 553
Query: 554 VGDENGKAIAWEKAFIQLAK 573
G ENGKA+AWE+A++ L K
Sbjct: 554 TGQENGKAVAWERAYVNLVK 573
>Q01KH5_ORYSA (tr|Q01KH5) H0409D10.4 protein OS=Oryza sativa GN=H0409D10.4 PE=4
SV=1
Length = 1372
Score = 528 bits (1360), Expect = e-147, Method: Compositional matrix adjust.
Identities = 284/560 (50%), Positives = 370/560 (66%), Gaps = 49/560 (8%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+IQSLCPTITG+VCCT +
Sbjct: 44 SRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVD 103
Query: 93 QL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGI 144
Q QA+P LVGCPACLRNFLNLFCE+SCSPNQSLFINVTS+ QV+ MTV+GI
Sbjct: 104 QFDTLHQQVQQAIPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSVKQVNNTMTVNGI 163
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
D YVT T+GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++ GSPY
Sbjct: 164 DYYVTSTYGEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYL 223
Query: 205 IDFKTTILDSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
I F + I S+ ++ +NA++YSC D SLG +KMG
Sbjct: 224 ITFPSDISGSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMG 283
Query: 264 SLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
SLK +C+D SL V+Y+VL+ + LFG S +PL +E + ++ +G
Sbjct: 284 SLKAKCLDFSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDKIHSS--NNG 339
Query: 323 EVLVIDPQRQ-------NEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+V Q S IQ ++S F+R +G + A+ P +VL SL + LLC
Sbjct: 340 KVPDSSAQVSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCI 399
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPSI 433
GL+RF VE RPEKLWV S+AA+EK++FDSHLAPFYRIEQL++AT S G + P+I
Sbjct: 400 GLIRFKVEIRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT---SAFGGSEAPTI 456
Query: 434 VTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDN 493
V D+N++LLF+IQ+K+D++RANYSG VSL+DICLKPLG +CATQS+L
Sbjct: 457 VNDNNMKLLFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVL------------ 504
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTK 553
QHYT+ ETC S F++P++P+T LGGF GNN++EASAF++TYPVNN +
Sbjct: 505 -----------QHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVVTYPVNNKVET 553
Query: 554 VGDENGKAIAWEKAFIQLAK 573
G ENGKA+AWE+A++ L K
Sbjct: 554 TGQENGKAVAWERAYVNLVK 573
>D8S0H8_SELML (tr|D8S0H8) Putative uncharacterized protein (Fragment)
OS=Selaginella moellendorffii GN=SELMODRAFT_106036 PE=4
SV=1
Length = 1225
Score = 511 bits (1316), Expect = e-142, Method: Compositional matrix adjust.
Identities = 265/551 (48%), Positives = 351/551 (63%), Gaps = 35/551 (6%)
Query: 34 RSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQ 93
R+ H+ +CAMYD+CGQR DGK LNCP P+V P S K+QSLCPTITG+VCCTE+Q
Sbjct: 1 RTKHAKNHCAMYDVCGQREDGKALNCPISVPAVTPSSSFSHKVQSLCPTITGDVCCTEQQ 60
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS-ISQVDGNMTVDGI 144
QAVP L GCPACLRNFLNLFCELSCSP+QSLFINVTS + Q TVDGI
Sbjct: 61 FDILRSQVQQAVPFLTGCPACLRNFLNLFCELSCSPDQSLFINVTSTVQQNSTTSTVDGI 120
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
+ +++E FG L+++CKDV+FG +NTRA+DFVG GA YKEW AF+G++ PGSPY
Sbjct: 121 EFFLSEEFGVNLFNSCKDVQFGALNTRAMDFVGGGAKTYKEWLAFIGRQADLYEPGSPYY 180
Query: 205 IDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMG 263
I F T+ +SSPM L+N ++ C D SL +++G
Sbjct: 181 IKFHTSANESSPMSLLNTKMFPCWDASLSCSCGDCPGAKECTESSLPPSPQKNACSVEIG 240
Query: 264 SLKVRCVDLSLAVLYIVLVFVLFGWI-XXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
K+ C+DL L +LY++L+ + W+ G E LL SE + +
Sbjct: 241 GTKILCIDLGLGILYLLLLVGIVAWLWVTTRRYEEPSDGEIREELLQSEETNGVEITPVE 300
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNV 382
L D E ++++LS ++R+ G W AR P +VL S+ + I+LC GL++ NV
Sbjct: 301 VGLEKDETSTPESHEPVLEKFLSRWFRSQGTWIARHPGVVLLLSILVTIILCIGLVKMNV 360
Query: 383 ETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELL 442
ET PE LWV P S AA EK+FFD+ L PFYRIEQLI+ATLP+ E+G P I+TDDN++L+
Sbjct: 361 ETNPENLWVSPGSAAATEKKFFDTELTPFYRIEQLILATLPD-ENGVSPPILTDDNLKLM 419
Query: 443 FEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEY 502
FEIQ KVD++R N SG +VSL DIC+KP G CATQS+L
Sbjct: 420 FEIQNKVDDLRGNLSGRMVSLQDICMKPFGTVCATQSVL--------------------- 458
Query: 503 CFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAI 562
QHY+S+E C SA+++P++P+TA+GGF G NY++A+AF++TYPVNNA++ N AI
Sbjct: 459 --QHYSSSENCLSAYQSPVDPSTAVGGFEGTNYTQATAFVVTYPVNNAVSSTEGANDAAI 516
Query: 563 AWEKAFIQLAK 573
AWEKAF++LAK
Sbjct: 517 AWEKAFVRLAK 527
>D8SB69_SELML (tr|D8SB69) Putative uncharacterized protein (Fragment)
OS=Selaginella moellendorffii GN=SELMODRAFT_112989 PE=4
SV=1
Length = 1226
Score = 508 bits (1309), Expect = e-141, Method: Compositional matrix adjust.
Identities = 264/551 (47%), Positives = 350/551 (63%), Gaps = 35/551 (6%)
Query: 34 RSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQ 93
R+ H+ +CAMYD+CGQR DGK LNCP P+V P S K+QSLCPTITG+VCCTE+Q
Sbjct: 1 RAKHAKNHCAMYDVCGQREDGKALNCPISVPAVTPSSSFSHKVQSLCPTITGDVCCTEQQ 60
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS-ISQVDGNMTVDGI 144
QAVP L GCPACLRNFLNLFCELSCSP+QSLFINVTS + Q TVDGI
Sbjct: 61 FDILRSQVQQAVPFLTGCPACLRNFLNLFCELSCSPDQSLFINVTSTVQQNSTTSTVDGI 120
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
+ +++E FG L+++CKDV+FG +NTRA+DFVG GA YKEW AF+G++ PGSPY
Sbjct: 121 EFFLSEEFGVNLFNSCKDVQFGALNTRAMDFVGGGAKTYKEWLAFIGRQADLYEPGSPYY 180
Query: 205 IDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMG 263
I F T+ +SSPM L+N ++ C D SL +++G
Sbjct: 181 IKFHTSANESSPMSLLNTKMFPCWDASLSCSCGDCPGAKECTESSLPPSPQKNACSVEIG 240
Query: 264 SLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSS-AEPLLVSEGRSFTNLPKDG 322
K+ C+DL L +LY++L+ + W+ + E LL SE + +
Sbjct: 241 GTKILCIDLGLGILYLLLLVGIVAWLWVTTRRYEEPSDAEIREELLQSEETNGVEITPVE 300
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNV 382
L D E ++++LS ++R+ G W AR P +VL S+ + I+LC GL++ NV
Sbjct: 301 VGLEKDETSTPESHEPVLEKFLSRWFRSQGTWIARHPGVVLLLSILVTIILCIGLVKMNV 360
Query: 383 ETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELL 442
ET PE LWV P S AA EK+FFD+ L PFYRIEQLI+ATLP+ E+G P I+TDDN++L+
Sbjct: 361 ETNPENLWVSPGSAAATEKKFFDTELTPFYRIEQLILATLPD-ENGVSPPILTDDNLKLM 419
Query: 443 FEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEY 502
FEIQ KVD++R N SG VSL DIC+KP G CATQS+L
Sbjct: 420 FEIQNKVDDLRGNLSGRTVSLQDICMKPFGTVCATQSVL--------------------- 458
Query: 503 CFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAI 562
QHY+S+E C SA+++P++P+TA+GGF G NY++A+AF++TYPVNNA++ N AI
Sbjct: 459 --QHYSSSENCLSAYQSPVDPSTAVGGFEGTNYTQATAFVVTYPVNNAVSSTEGANDAAI 516
Query: 563 AWEKAFIQLAK 573
AWEKAF++LAK
Sbjct: 517 AWEKAFVRLAK 527
>B9FBZ9_ORYSJ (tr|B9FBZ9) Putative uncharacterized protein OS=Oryza sativa subsp.
japonica GN=OsJ_15793 PE=4 SV=1
Length = 1211
Score = 489 bits (1260), Expect = e-135, Method: Compositional matrix adjust.
Identities = 263/552 (47%), Positives = 354/552 (64%), Gaps = 50/552 (9%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+IQSLCPTITG+VCCT +
Sbjct: 44 SRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVD 103
Query: 93 QLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETF 152
Q + + QV+ MTV+GID YVT T+
Sbjct: 104 QFDTLH-------------------------------QQVQQVNNTMTVNGIDYYVTSTY 132
Query: 153 GEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTIL 212
GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++ GSPY I F + I
Sbjct: 133 GEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITFPSDIS 192
Query: 213 DSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVD 271
S+ ++ +NA++YSC D SLG +KMGSLK +C+D
Sbjct: 193 GSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMGSLKAKCLD 252
Query: 272 LSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQ 330
SL V+Y+VL+ + LFG S +PL +E + ++ +G+V Q
Sbjct: 253 FSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDKIHSS--NNGKVPDSSAQ 308
Query: 331 RQ-------NEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
S IQ ++S F+R +G + A+ P +VL SL + LLC GL+RF VE
Sbjct: 309 VSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCIGLIRFKVE 368
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPSIVTDDNIEL 441
RPEKLWV S+AA+EK++FDSHLAPFYRIEQL++AT S G + P+IV D+N++L
Sbjct: 369 IRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT---SAFGGSEAPTIVNDNNMKL 425
Query: 442 LFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAE 501
LF+IQ+K+D++RANYSG VSL+DICLKPLG +CATQS+LQYFQ+DP +D+ G++HA+
Sbjct: 426 LFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVLQYFQLDPKKYDD-SGIDHAK 484
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
+CFQHYT+ ETC S F++P++P+T LGGF GNN++EASAF+ITYPVNN + G ENGKA
Sbjct: 485 FCFQHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVITYPVNNKVETTGQENGKA 544
Query: 562 IAWEKAFIQLAK 573
+AWE+A++ L K
Sbjct: 545 VAWERAYVNLVK 556
>B8AT56_ORYSI (tr|B8AT56) Putative uncharacterized protein OS=Oryza sativa subsp.
indica GN=OsI_16991 PE=4 SV=1
Length = 1257
Score = 489 bits (1258), Expect = e-135, Method: Compositional matrix adjust.
Identities = 262/552 (47%), Positives = 354/552 (64%), Gaps = 50/552 (9%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+IQSLCPTITG+VCCT +
Sbjct: 19 SRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVD 78
Query: 93 QLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETF 152
Q + + QV+ MTV+GID YVT T+
Sbjct: 79 QFDTLH-------------------------------QQVQQVNNTMTVNGIDYYVTSTY 107
Query: 153 GEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTIL 212
GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++ GSPY I F + I
Sbjct: 108 GEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITFPSDIS 167
Query: 213 DSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVD 271
S+ ++ +NA++YSC D SLG +KMGSLK +C+D
Sbjct: 168 GSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMGSLKAKCLD 227
Query: 272 LSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQ 330
SL V+Y+VL+ + LFG S +PL +E + ++ +G+V Q
Sbjct: 228 FSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDKIHSS--NNGKVPDSSAQ 283
Query: 331 RQ-------NEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
S IQ ++S F+R +G + A+ P +VL SL + LLC GL+RF VE
Sbjct: 284 VSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCIGLIRFKVE 343
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPSIVTDDNIEL 441
RPEKLWV S+AA+EK++FDSHLAPFYRIEQL++AT S G + P+IV D+N++L
Sbjct: 344 IRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT---SAFGGSEAPTIVNDNNMKL 400
Query: 442 LFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAE 501
LF+IQ+K+D++RANYSG VSL+DICLKPLG +CATQS+LQYFQ+DP +D+ G++HA+
Sbjct: 401 LFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVLQYFQLDPKKYDD-SGIDHAK 459
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
+CFQHYT+ ETC S F++P++P+T LGGF GNN++EASAF++TYPVNN + G ENGKA
Sbjct: 460 FCFQHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVVTYPVNNKVETTGQENGKA 519
Query: 562 IAWEKAFIQLAK 573
+AWE+A++ L K
Sbjct: 520 VAWERAYVNLVK 531
>A9RFW8_PHYPA (tr|A9RFW8) Uncharacterized protein (Fragment) OS=Physcomitrella
patens subsp. patens GN=PHYPADRAFT_113528 PE=4 SV=1
Length = 1262
Score = 484 bits (1247), Expect = e-134, Method: Compositional matrix adjust.
Identities = 257/555 (46%), Positives = 334/555 (60%), Gaps = 52/555 (9%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL------- 94
CAMYDICG R+DGK LNC PSP+V P S K+QSLCPTI G+VCCT Q
Sbjct: 1 CAMYDICGNRTDGKPLNCATPSPAVTPDRAFSLKLQSLCPTIVGDVCCTPTQFNLLRSNV 60
Query: 95 -QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFG 153
QAVP L GCPACLRNFLN FCE SCSPNQ F+NVT+++ N V ++ ++T+ +G
Sbjct: 61 QQAVPFLTGCPACLRNFLNFFCEFSCSPNQGSFLNVTAVN--GANNAVAALEFFITDEYG 118
Query: 154 EGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILD 213
Y +CKDVKF +MN R++DF+G GA NY EWFAF+G++ P PGSPY I F+T + +
Sbjct: 119 RKFYDSCKDVKFTSMNIRSMDFIGGGAQNYSEWFAFMGKEAAPSLPGSPYPISFRTDVKE 178
Query: 214 SSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX-XIKMGSLKVRCVD 271
+P + N+SV +C+D S +++ +V C+
Sbjct: 179 GNPAVTPFNSSVIACSDPSFECSCGDCPLVNSCAEPNPPAPSETKGCHVQIAGSQVACLT 238
Query: 272 LSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKD---------- 321
L++ +LY LV ++ GW SS E L N +
Sbjct: 239 LAVIILYGCLVVIILGWWLMFRSPRKEM--SSKERLNPDAQSDLANKAQQTDVDSQIRSP 296
Query: 322 GEVLVIDPQRQN---EVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
E+ +DP+ QN +VQ + N YR YG A VL ++ I ++LC GL+
Sbjct: 297 NELDRLDPKHQNHPAKVQVYTFSCYCLNIYRIYGELVAYNTKKVLAIAIVITVVLCLGLI 356
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN 438
R VETRPEKLWV SKAAEEK+FFDSHLAPFYRIEQLI+AT+P S+ PPSIVTD N
Sbjct: 357 RLRVETRPEKLWVSYGSKAAEEKKFFDSHLAPFYRIEQLILATVPGSKDSPPPSIVTDAN 416
Query: 439 IELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVE 498
++LLF++QEKVD +R N+SG L+SL DICLKPLG CATQSILQY
Sbjct: 417 LKLLFDLQEKVDNVRGNHSGKLISLQDICLKPLGTPCATQSILQY--------------- 461
Query: 499 HAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN 558
Y+S+ETC SAF P++PTT LGGF+GNNY++A+A ++TYPV NA++ G+ N
Sbjct: 462 --------YSSSETCLSAFGGPVDPTTILGGFTGNNYTQATALVVTYPVINAVS--GEGN 511
Query: 559 GKAIAWEKAFIQLAK 573
AIAWE FI++ K
Sbjct: 512 AAAIAWENEFIRVVK 526
>G7KFF1_MEDTR (tr|G7KFF1) Niemann-Pick C1 protein OS=Medicago truncatula
GN=MTR_5g099070 PE=4 SV=1
Length = 1568
Score = 447 bits (1150), Expect = e-123, Method: Compositional matrix adjust.
Identities = 263/423 (62%), Positives = 298/423 (70%), Gaps = 22/423 (5%)
Query: 31 QISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCT 90
QI + HS EYC+MYDICGQR+DGKVLNCPYPSPSVKP+DLLSAKIQSLCP++ GNVCCT
Sbjct: 55 QIMSNTHSEEYCSMYDICGQRTDGKVLNCPYPSPSVKPNDLLSAKIQSLCPSLNGNVCCT 114
Query: 91 EEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVD 142
E+Q QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS+S V+GN+TVD
Sbjct: 115 EQQFETLRAQVQQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSVSLVNGNITVD 174
Query: 143 GIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSP 202
ID Y TETFG+GLY ACKDVKFGTMNTRAIDFVG GA+NY+EWF+FLGQKVP GFPGSP
Sbjct: 175 AIDFYATETFGDGLYQACKDVKFGTMNTRAIDFVGGGASNYQEWFSFLGQKVPLGFPGSP 234
Query: 203 YSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
YSI FKTTI DSSPM+ MNA VYSCNDTSLG I+M
Sbjct: 235 YSIHFKTTIPDSSPMKPMNAPVYSCNDTSLGCSCGDCPSSPVCSGSEPSPPTKDPCSIRM 294
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL---VSEGRSFTNLP 319
GSLKVRCVD SLA+LY++LVFVL GW+ GS EPLL EG SFTN+
Sbjct: 295 GSLKVRCVDFSLALLYVLLVFVLLGWVLLQRTRQERRVGSDVEPLLNDMGDEGSSFTNIQ 354
Query: 320 KD----GEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+D E V+DPQRQ +Q+SF+Q +LS FYR+YGRWAA RP VLC SL IV+LLC
Sbjct: 355 RDETHPEEEQVMDPQRQKAMQFSFVQGYLSRFYRSYGRWAAMRPNTVLCLSLVIVLLLCL 414
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
GLLRF VETRPEK EE + Y L+I +P + +I T
Sbjct: 415 GLLRFEVETRPEK------QNGVEEGNMLGLYTFS-YDQHGLLILRVPSILPTRTVAIAT 467
Query: 436 DDN 438
D+N
Sbjct: 468 DNN 470
Score = 369 bits (946), Expect = 3e-99, Method: Compositional matrix adjust.
Identities = 183/258 (70%), Positives = 208/258 (80%), Gaps = 13/258 (5%)
Query: 329 PQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV--------ILLCFGLLRF 380
P++QN V+ + + Y +G R P+I+ ++AI I+ CF ++
Sbjct: 425 PEKQNGVEEGNMLGLYTFSYDQHGLLILRVPSILPTRTVAIATDNNANFNIIHCFPIIER 484
Query: 381 NVETRPE-----KLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
+ + +LW GP SKAAEEK++FDSHLAPFYRIEQLIIAT+P+SEHGKPPSI+T
Sbjct: 485 SSVHKGRTILTLQLWTGPGSKAAEEKDYFDSHLAPFYRIEQLIIATIPDSEHGKPPSIIT 544
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
+DNIELLFEIQEKVD IRANYSGL VSLSDICLKPLG+DCATQSILQYFQMD DN+D+YG
Sbjct: 545 EDNIELLFEIQEKVDGIRANYSGLFVSLSDICLKPLGDDCATQSILQYFQMDSDNYDDYG 604
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVG 555
GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAL K G
Sbjct: 605 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALAKFG 664
Query: 556 DENGKAIAWEKAFIQLAK 573
DENGKAIAWEKAFIQLAK
Sbjct: 665 DENGKAIAWEKAFIQLAK 682
>I1PNW1_ORYGL (tr|I1PNW1) Uncharacterized protein OS=Oryza glaberrima PE=4 SV=1
Length = 1194
Score = 418 bits (1075), Expect = e-114, Method: Compositional matrix adjust.
Identities = 238/552 (43%), Positives = 324/552 (58%), Gaps = 84/552 (15%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEE 92
SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+IQSLCPTITG+VCCT +
Sbjct: 44 SRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARIQSLCPTITGDVCCTVD 103
Query: 93 QLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETF 152
Q + + QV+ MTV+GID YVT T+
Sbjct: 104 QFDTLH-------------------------------QQVQQVNNTMTVNGIDYYVTSTY 132
Query: 153 GEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTIL 212
GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++ GSPY I F + I
Sbjct: 133 GEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADLNQIGSPYLITFPSDIS 192
Query: 213 DSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVD 271
S+ ++ +NA++YSC D SLG +KMGSLK +C+D
Sbjct: 193 GSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTETSCSVKMGSLKAKCLD 252
Query: 272 LSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQ 330
SL V+Y+VL+ + LFG S +PL +E + ++ +G+V Q
Sbjct: 253 FSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDKIHSS--NNGKVPDSSAQ 308
Query: 331 RQ-------NEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVE 383
S IQ ++S F+R +G + A+ P +VL SL + LLC GL+RF VE
Sbjct: 309 VSEAASAPVQSAHPSVIQTYMSTFFRKHGTFVAKHPLLVLFVSLLVPTLLCIGLIRFKVE 368
Query: 384 TRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPSIVTDDNIEL 441
RPEKLWV S+AA+EK++FDSHLAPFYRIEQL++AT S G + P+IV D+N++L
Sbjct: 369 IRPEKLWVSSGSRAADEKQYFDSHLAPFYRIEQLVLAT---SAFGGSEAPTIVNDNNMKL 425
Query: 442 LFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAE 501
LF+IQ+K YFQ+DP +D+ G++HA+
Sbjct: 426 LFQIQKK----------------------------------YFQLDPKKYDD-SGIDHAK 450
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
+CFQHYT+ ETC S F++P++P+T LGGF GNN++EASAF+ITYPVNN + +G ENGKA
Sbjct: 451 FCFQHYTTEETCLSTFQSPIDPSTILGGFPGNNFTEASAFVITYPVNNKVETIGQENGKA 510
Query: 562 IAWEKAFIQLAK 573
+AWE+A++ L K
Sbjct: 511 VAWERAYVNLVK 522
>M0RSW2_MUSAM (tr|M0RSW2) Uncharacterized protein OS=Musa acuminata subsp.
malaccensis PE=4 SV=1
Length = 396
Score = 408 bits (1048), Expect = e-111, Method: Compositional matrix adjust.
Identities = 211/399 (52%), Positives = 270/399 (67%), Gaps = 35/399 (8%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL--------Q 95
MY ICGQRSDGKVLNCP + SVKP +LLS+ IQSLCPTIT NVCC+ +Q Q
Sbjct: 1 MYGICGQRSDGKVLNCPNRTHSVKPDELLSSTIQSLCPTITDNVCCSADQFDTLRGQVQQ 60
Query: 96 AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEG 155
A+P+LVGCPACLRNFLNLFCELSCSPNQSLFINVTSI +V+G + VD ID +VT FGE
Sbjct: 61 AIPLLVGCPACLRNFLNLFCELSCSPNQSLFINVTSIKKVNGTLAVDAIDFFVTHYFGEQ 120
Query: 156 LYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
L+++CKDVKFG+MNTRA+DFVGAGA+NY +W AFLG++ PGSPY+I F++ I DS+
Sbjct: 121 LFNSCKDVKFGSMNTRAMDFVGAGAHNYADWLAFLGRRANLDVPGSPYAITFRSNISDST 180
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXX-XXXXXXXXXIKMGSLKVRCVDLSL 274
M+ MN +VYSC D+SLG I +GSLK++C+D SL
Sbjct: 181 GMKPMNTTVYSCGDSSLGCSCGDCPSSAVCLDSSTPAQHAKQSCSINIGSLKIKCLDFSL 240
Query: 275 AVLYIVLV--FVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKD-----GEVLVI 327
A++Y+ LV F+L+G++ A P S ++ N+ D G+
Sbjct: 241 AIVYLFLVSAFLLWGFVYRK---------KRAGP---SRTKALLNVRDDNNHNSGDKKEA 288
Query: 328 DPQRQNEV-------QYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
Q EV + S IQ ++SNF+R YG + ++ PT++LC SL + +LLC GL+RF
Sbjct: 289 PSQISEEVPPVVKAHRPSVIQLYMSNFFRKYGSFVSKNPTLILCLSLVVPLLLCLGLIRF 348
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII 419
VETRPEKLWVGP SKAA+EK++FDSHLAPFYRIEQ++I
Sbjct: 349 KVETRPEKLWVGPGSKAAKEKQYFDSHLAPFYRIEQVLI 387
>C7J1V6_ORYSJ (tr|C7J1V6) Os04g0563801 protein OS=Oryza sativa subsp. japonica
GN=Os04g0563801 PE=4 SV=1
Length = 963
Score = 351 bits (900), Expect = 6e-94, Method: Compositional matrix adjust.
Identities = 221/561 (39%), Positives = 293/561 (52%), Gaps = 136/561 (24%)
Query: 20 LSWFSPSLTAAQ---ISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKI 76
L + P A Q SR + + YC+MY IC QRSDGKVLNC + +VKP L SA+I
Sbjct: 28 LVFLVPPTRAQQSNGTSRVVPAEGYCSMYGICAQRSDGKVLNCVNATKAVKPDTLFSARI 87
Query: 77 QSLCPTITGNVCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
QSLCPTITG+VCCT +Q + + QV+
Sbjct: 88 QSLCPTITGDVCCTVDQFDTLH-------------------------------QQVQQVN 116
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPP 196
MTV+GID YVT T+GE LY++CKDVKFGT+NTRA+DF+G GA NYKEW AF+G++
Sbjct: 117 NTMTVNGIDYYVTSTYGEELYNSCKDVKFGTLNTRAMDFLGGGAKNYKEWMAFIGRQADL 176
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXXXXXXXXXXXX 255
GSPY I F + I S+ ++ +NA++YSC D SLG
Sbjct: 177 NQIGSPYLITFPSDISGSTAVKPLNATIYSCGDPSLGCSCGDCPSSSVCTGSLLPQLNTE 236
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+KMGSLK +C+D SL V+Y+VL+ + LFG S +PL +E +
Sbjct: 237 TSCSVKMGSLKAKCLDFSLVVVYLVLLCIFLFGAFLHRTRRSGIF--SHTKPLKNAEDK- 293
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
I +V S Q W+S+ RA
Sbjct: 294 ------------IHSSNNGKVPDSSAQLWVSSGSRA------------------------ 317
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG--KPPS 432
A E++ F DSHLAPFYRIEQL++AT S G + P+
Sbjct: 318 ----------------------ADEKQYF-DSHLAPFYRIEQLVLAT---SAFGGSEAPT 351
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
IV D+N++LLF+IQ+K+D++RANYSG VSL+DICLKPLG +CATQS+LQYFQ+DP +D
Sbjct: 352 IVNDNNMKLLFQIQKKIDDLRANYSGSTVSLADICLKPLGTECATQSVLQYFQLDPKKYD 411
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALT 552
+ G++HA++CFQ ASAF+ITYPVNN +
Sbjct: 412 D-SGIDHAKFCFQ--------------------------------ASAFVITYPVNNKVE 438
Query: 553 KVGDENGKAIAWEKAFIQLAK 573
G ENGKA+AWE+A++ L K
Sbjct: 439 TTGQENGKAVAWERAYVNLVK 459
>I0Z7Q3_9CHLO (tr|I0Z7Q3) Multidrug efflux transporter AcrB transmembrane
domain-containing protein OS=Coccomyxa subellipsoidea
C-169 GN=COCSUDRAFT_27169 PE=4 SV=1
Length = 1321
Score = 336 bits (862), Expect = 1e-89, Method: Compositional matrix adjust.
Identities = 213/599 (35%), Positives = 312/599 (52%), Gaps = 85/599 (14%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT----GNVCCTEE 92
H CA Y ICG R DG VLNC + + D + K+Q +CP + G CCTEE
Sbjct: 42 HEKGVCATYGICGHRKDGDVLNCANNTEAQPVSDAAARKLQDVCPQLVAETNGKFCCTEE 101
Query: 93 QL----QAVPI----LVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV-DGNMTV-D 142
Q+ Q + I LVGCPAC +NF + FC L+CSP+QS F NV+ I + D N TV +
Sbjct: 102 QIDTLSQQIQIAGIFLVGCPACNQNFKHFFCTLTCSPDQSTFTNVSEIQKASDNNKTVVE 161
Query: 143 GIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLG----QKVPPGF 198
+D++V +++G+ Y +CKDV + N +A+ F+G GA N++E+F FLG ++VPP
Sbjct: 162 ELDIFVADSYGKQFYDSCKDVVYAAANMKAMSFIGGGAKNFQEFFEFLGMVKDKRVPPA- 220
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXX--XXXXXXXXXXXXXXXXXX 256
GSP+ ++F M N SV +C +++L
Sbjct: 221 -GSPFQMNFPGEAQTPQGMLAANESVPACWESALKCSCGDCPDGPQCSPPPAPPPPPVTG 279
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+ M + C D+SL +LYIVLV VL I S EPL +F
Sbjct: 280 CTAVGMAPDSISCQDVSLILLYIVLVPVLALCIRYKTLH------SCGEPL------TFR 327
Query: 317 NLPKDGEVLVIDPQRQNE--------------------------VQYSFIQEWLSNFYRA 350
N+ L QR N +QYS +++WL ++Y
Sbjct: 328 NMLG----LAAASQRSNMWAEELAAAADAERDAEEEPPKSLGTGLQYSLVEKWLRSWYFE 383
Query: 351 YGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAP 410
G+ AR P VL ++ V++ G+LRF VET P++LWVGP S AA EK ++
Sbjct: 384 QGQRCARHPWRVLGFAVLAVLICSLGMLRFRVETDPQRLWVGPTSLAATEKAAYEESFGA 443
Query: 411 FYRIEQLIIATLPES-----EHGKPPSIVTDDNIELLFEIQEKVD--EIRANYSGLLVSL 463
FYRIEQLI++T P++ PSIVTD+NI+LLF +Q +VD E+ S +L
Sbjct: 444 FYRIEQLILSTTPKAASQYIAQSGLPSIVTDENIKLLFRMQAEVDALEVSVGDSNATATL 503
Query: 464 SDICLKPLGEDCATQSILQYFQMDPDNFDN----YGGVEHAEYCFQHYTSTETCFSAFKA 519
D+C KP G CATQSILQ+++MD D ++ YG ++CF H+++ C S F+A
Sbjct: 504 QDVCYKPFGAACATQSILQFWKMDEDIYEKGEPPYGMKLSPDFCFSHWST--QCRSTFEA 561
Query: 520 PLEPTTALGGFSG-----NNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P++P LGGF N ++++AF++T+PV+++ G+ +AWE FI+LA+
Sbjct: 562 PMDPHVILGGFPNGPDFRNFSADSTAFVVTFPVDSS---SGNRCSLPLAWEAEFIELAR 617
>I1J0L7_BRADI (tr|I1J0L7) Uncharacterized protein OS=Brachypodium distachyon
GN=BRADI5G18407 PE=4 SV=1
Length = 930
Score = 315 bits (807), Expect = 3e-83, Method: Compositional matrix adjust.
Identities = 139/230 (60%), Positives = 187/230 (81%), Gaps = 2/230 (0%)
Query: 344 LSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEF 403
+S F+R +G + R P +VL +S+ + ++LC GL+RF VETRPEKLWV P S+AA+EK++
Sbjct: 1 MSTFFRRHGIFVTRHPLLVLFASILVPVILCIGLIRFKVETRPEKLWVSPGSRAADEKQY 60
Query: 404 FDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSL 463
FDSHLAPFYRIEQL++AT S+ + P+IV ++N++LLF+IQ KVD++RANYSG VSL
Sbjct: 61 FDSHLAPFYRIEQLVLAT-SASDQSEAPTIVNENNMKLLFQIQNKVDDLRANYSGSTVSL 119
Query: 464 SDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEP 523
+DICLKPL DCATQS+LQYFQ+D +D+ G++HA++CFQHY+S ETC S F++P++P
Sbjct: 120 ADICLKPLSTDCATQSVLQYFQLDRKKYDD-SGIDHAKFCFQHYSSEETCLSTFQSPIDP 178
Query: 524 TTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+T LGGF G+N+SEASAFIITYPVNN + G ENGKA+AWE+A+I L K
Sbjct: 179 STILGGFPGSNFSEASAFIITYPVNNKVETTGQENGKAVAWERAYINLVK 228
>G0RBC0_HYPJQ (tr|G0RBC0) Predicted protein OS=Hypocrea jecorina (strain QM6a)
GN=TRIREDRAFT_75603 PE=4 SV=1
Length = 1272
Score = 263 bits (671), Expect = 2e-67, Method: Compositional matrix adjust.
Identities = 175/558 (31%), Positives = 272/558 (48%), Gaps = 31/558 (5%)
Query: 23 FSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCP 81
F S AA+ H CA CG++S GK L C + P D L ++ LC
Sbjct: 14 FVGSSAAAESYTPKHELGRCAFRGQCGKQSLFGKELPCVDNGLAHDPDDDLRKELVELCG 73
Query: 82 T--ITGNVCCTEEQLQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTS 131
G VCC EQ+QA+ +G CPAC NF N+FC+ +CSP+QS FINVT
Sbjct: 74 AEWSEGAVCCNMEQVQALKKEMGTPKTLIGSCPACKHNFFNMFCKFTCSPDQSTFINVTD 133
Query: 132 ISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLG 191
+ +G + V +D ++E +G GLY++CK+VKFG N+RA+D +G GA NY + FLG
Sbjct: 134 AASKNGKLLVTELDQLISEEYGSGLYNSCKEVKFGGANSRAMDLIGGGAKNYHDMLKFLG 193
Query: 192 QKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
K P F GSP+ I+F D M+ + CND
Sbjct: 194 DKKP--FVGSPFQINFPEE-YDQPGMQPLEMKPKKCNDEDPAYRCVCVDCPEVCPTLPDV 250
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSE 311
K+ L + + +VL + L+ +FG I + L+ E
Sbjct: 251 KEAGSCRVGKLPCLSFASI-FTYSVLLVALLTAVFGHIFWFRYLKRRVERTR----LLHE 305
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
S ++ +G ++ D R + ++ + +R G AAR P + + SL +V
Sbjct: 306 A-SHSDDEDEGGPILTDAMRDQPTKRYWLNDKCDKAFRHLGNTAARFPALTIGISLVVVA 364
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
+L G +RF++E P +LWV P S AA+EKE+FDS+ PF+R E++ + +S P
Sbjct: 365 VLSAGWIRFDIEQDPARLWVSPSSAAAQEKEYFDSNFGPFFRAEKIFLVNDTDSSDSSP- 423
Query: 432 SIVTDDNIELLFEIQEKVDEIRA-NYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
+++ + ++ ++++ V+ ++ Y+ SL D+C KP G+ C QS+ QY+ +
Sbjct: 424 -VLSYETLKWWKDVEKSVESLKGPTYAS---SLDDVCFKPTGDACVVQSVTQYWYSKGGD 479
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNA 550
D + C + S C AF P+EPT LGG+ ++ +++ A +T+ VNNA
Sbjct: 480 IDPKYWKDDLRSCAK---SPVDCRPAFGQPIEPTMILGGYD-DDVADSQAMTVTWVVNNA 535
Query: 551 LTKVGDENGKAIAWEKAF 568
K DE +AI WE A
Sbjct: 536 PEK-SDELLRAIDWENAL 552
>G9MVK1_HYPVG (tr|G9MVK1) Uncharacterized protein OS=Hypocrea virens (strain
Gv29-8 / FGSC 10586) GN=TRIVIDRAFT_52300 PE=4 SV=1
Length = 1272
Score = 261 bits (668), Expect = 5e-67, Method: Compositional matrix adjust.
Identities = 179/568 (31%), Positives = 270/568 (47%), Gaps = 37/568 (6%)
Query: 20 LSWFSPSLTAAQISRSIHSNEY--------CAMYDICGQRSD-GKVLNCPYPSPSVKPHD 70
L+ S L A S H+ Y CA CG++S GK L C + P +
Sbjct: 3 LAVLSSGLAALLFGVSAHAESYTPKHELGRCAFRGQCGKQSIFGKELPCVDNGLAHDPDE 62
Query: 71 LLSAKIQSLCPTITGN--VCCTEEQLQAVPILVG--------CPACLRNFLNLFCELSCS 120
L ++ LC G VCC EQ+QA+ +G CPAC NF NLFC+ +CS
Sbjct: 63 DLRKELVELCGAEWGEGPVCCNMEQVQALKSEMGTPKTLIGSCPACKHNFFNLFCKFTCS 122
Query: 121 PNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGA 180
P+QS FINVT + +G + V +D V+E +G GLY +CK+VKFG N+RA+D +G GA
Sbjct: 123 PDQSTFINVTDAAPKNGKLLVTELDQLVSEEYGSGLYDSCKEVKFGGANSRAMDLIGGGA 182
Query: 181 NNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXX 240
NY + FLG K P F GSP+ I+F ME + CND
Sbjct: 183 KNYHDMLKFLGDKKP--FVGSPFQINFPEE-YKQPGMEPLEMKPKKCNDED---PAYRCV 236
Query: 241 XXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXX 300
++G K+ C+ + Y VL+ LF +
Sbjct: 237 CVDCPEVCPTLPDVKEAGSCRVG--KLPCLSFASIFTYGVLLLALFTAVFGHIFWFKYLK 294
Query: 301 GSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPT 360
L+ E + + G +L D R + ++ + + G AAR P
Sbjct: 295 RRVERTRLLHESYHSDDEDEGGPILT-DAMRDQPTKRYWLNDKCDKAFNHLGSSAARFPV 353
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
+ + SL +V +L G RF++E P +LWV P S AA+EK++FDS+ PF+R E++ +
Sbjct: 354 LTIGISLLVVGILSAGWFRFDIEQDPARLWVSPASAAAQEKDYFDSNFGPFFRAEKIFLV 413
Query: 421 TLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSI 480
++E P +++ + ++ E+++ V++++ + G SLSD+C KP G+ C QS+
Sbjct: 414 N--DTESSGPSPVLSYETLQWWTEVEKSVEKLKGSTYG--SSLSDVCFKPTGDSCVVQSV 469
Query: 481 LQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASA 540
QY+ + D E C + S C AF P+EPT LGG+ ++ +E+ A
Sbjct: 470 TQYWYSKGGDIDPNYWKEDLRSCAR---SPVDCRPAFGQPIEPTMILGGYD-DDVAESQA 525
Query: 541 FIITYPVNNALTKVGDENGKAIAWEKAF 568
+T+ VNNA K D +AI WE A
Sbjct: 526 ITVTWVVNNAPEK-SDTLLRAIDWENAL 552
>M7ZB10_TRIUA (tr|M7ZB10) Niemann-Pick C1 protein OS=Triticum urartu
GN=TRIUR3_20018 PE=4 SV=1
Length = 1199
Score = 259 bits (662), Expect = 2e-66, Method: Compositional matrix adjust.
Identities = 116/193 (60%), Positives = 154/193 (79%), Gaps = 2/193 (1%)
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIE 440
NV +LWV P S+ A EK++FDSHLAPFYRIEQL++AT S + P+IV D+N +
Sbjct: 254 NVPENSVQLWVSPGSQTAYEKQYFDSHLAPFYRIEQLVLAT-SASGQLEAPTIVNDNNFK 312
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHA 500
LLF+IQ+K+D++RANYSG VSL+DICLKPL DCATQS+LQYFQ+DP D+ G ++HA
Sbjct: 313 LLFQIQKKIDDLRANYSGSTVSLADICLKPLSTDCATQSVLQYFQLDPKKHDDLG-IDHA 371
Query: 501 EYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK 560
++CF+HY+S ETC S F++P++P+T LGGF G+N++EASAF+ITYPVNN + G ENGK
Sbjct: 372 KFCFEHYSSEETCLSTFQSPIDPSTILGGFPGSNFTEASAFVITYPVNNKVETTGQENGK 431
Query: 561 AIAWEKAFIQLAK 573
A+AWE+A+I L K
Sbjct: 432 AMAWERAYINLVK 444
Score = 221 bits (562), Expect = 8e-55, Method: Compositional matrix adjust.
Identities = 104/165 (63%), Positives = 123/165 (74%), Gaps = 8/165 (4%)
Query: 28 TAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNV 87
+A Q R + + YC+MY IC R+DGKVLNC + +VKP L S +IQSLCPTITG+V
Sbjct: 11 SAQQSPRVVPAEGYCSMYGICANRTDGKVLNCVNATKAVKPDTLFSTRIQSLCPTITGDV 70
Query: 88 CCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNM 139
CCT +Q QAVP LVGCPACLRNFLNLFCE+SCSPNQSLFINVTS QV
Sbjct: 71 CCTVDQFDTLHQQVQQAVPFLVGCPACLRNFLNLFCEMSCSPNQSLFINVTSAKQVKNIT 130
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYK 184
TVDGID Y+T +GE LY++CK+VKFGT+NTRA+DF+G GA YK
Sbjct: 131 TVDGIDYYITSNYGEELYNSCKEVKFGTLNTRAMDFLGGGAKTYK 175
>M8C7J7_AEGTA (tr|M8C7J7) Niemann-Pick C1 protein OS=Aegilops tauschii
GN=F775_23414 PE=4 SV=1
Length = 1501
Score = 258 bits (658), Expect = 6e-66, Method: Compositional matrix adjust.
Identities = 115/193 (59%), Positives = 154/193 (79%), Gaps = 2/193 (1%)
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIE 440
NV +LWV P S+ A EK++FDSHLAPFYRIEQL++AT S+ + P+IV D+N +
Sbjct: 298 NVPENSAQLWVSPGSQTAYEKQYFDSHLAPFYRIEQLVLAT-SASDQLEAPTIVNDNNFK 356
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHA 500
LLF+IQ+K+D++RANYSG VSL+DICLKPL DCATQS+LQYFQ+DP D+ G ++HA
Sbjct: 357 LLFQIQKKIDDLRANYSGSTVSLADICLKPLSTDCATQSVLQYFQLDPKKHDDLG-IDHA 415
Query: 501 EYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK 560
++CF+HY+S ETC S F++P++P+T LGGF G+N++EASAF+ITYPVNN + G EN K
Sbjct: 416 KFCFEHYSSEETCLSTFQSPIDPSTILGGFPGSNFTEASAFVITYPVNNKVETTGQENAK 475
Query: 561 AIAWEKAFIQLAK 573
A+AWE+A+I L K
Sbjct: 476 AMAWERAYINLVK 488
Score = 183 bits (465), Expect = 1e-43, Method: Compositional matrix adjust.
Identities = 105/286 (36%), Positives = 143/286 (50%), Gaps = 34/286 (11%)
Query: 67 KPHDLLSAKIQSLCPTITGNVCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLF 126
KP L S +IQSLCPTITG+VCCT +Q +
Sbjct: 76 KPDTLFSTRIQSLCPTITGDVCCTVDQFDTLH---------------------------- 107
Query: 127 INVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEW 186
+ QVD TVDGID Y+T +GE LY++CK+VKFGT+NTRA+DF+G GA YKEW
Sbjct: 108 ---QQVQQVDNITTVDGIDYYITSNYGEELYNSCKEVKFGTLNTRAMDFLGGGAKTYKEW 164
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLG-XXXXXXXXXXXX 245
FAFLG++ P PGSPY I ++ + DSS ++ +N +VYSC D SLG
Sbjct: 165 FAFLGRQANPNEPGSPYLITYRPDLSDSSGVKPLNTTVYSCGDPSLGCSCGDCPSSSVCM 224
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAE 305
+KMGSLK C+D SL V+YIV + + W S +
Sbjct: 225 GSLLPQSKTETSCSVKMGSLKAECLDFSLVVVYIVFLCAILLWGLLYRTRGRTGFPSQTK 284
Query: 306 PLLVSEGRSFT--NLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYR 349
P ++ +S N+P++ L + P Q + + L+ FYR
Sbjct: 285 PPKNADDKSNNNGNVPENSAQLWVSPGSQTAYEKQYFDSHLAPFYR 330
>C5FQM2_ARTOC (tr|C5FQM2) Niemann-Pick C1 protein OS=Arthroderma otae (strain
ATCC MYA-4605 / CBS 113480) GN=MCYG_04994 PE=4 SV=1
Length = 1270
Score = 258 bits (658), Expect = 7e-66, Method: Compositional matrix adjust.
Identities = 174/562 (30%), Positives = 276/562 (49%), Gaps = 51/562 (9%)
Query: 36 IHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEE 92
+H CA+ CG++S G L CP + +P + K+ LC G VCC EE
Sbjct: 26 VHEAGRCAIRGNCGKQSFFGGELPCPDNGLAHEPDQRVRQKLVDLCGKKWEDGPVCCKEE 85
Query: 93 QLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGI 144
Q+ A+ ++ CPAC NF NLFC +CSPNQSLFINVT++++V+G + V +
Sbjct: 86 QINALSSNLKLASGVISSCPACKENFFNLFCTFTCSPNQSLFINVTNVAEVNGKLLVTEL 145
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
D +E + Y +CK+VK G +A+DF+G GA NY ++ FLG K GSP+
Sbjct: 146 DNLWSEEYQSNFYDSCKNVKNGASGGKAMDFIGGGAKNYTQFLKFLGDK---KLLGSPFQ 202
Query: 205 IDFKT--TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
I+F+T + D M+ + SC D ++
Sbjct: 203 INFRTEPRLPDDQSMKPVPDETRSCADKD---EVYRCSCIDCPDVCAELPAIKGEHHCRV 259
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
G+L C+ + AVL + +L + + E + + + + ++ +G
Sbjct: 260 GNLP--CLTFA-AVLVYSISLMLIVVLAIARSAFKRHRARNIERVRLLQDDAPSDEDDEG 316
Query: 323 EVL----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
EV+ + P R N V L N + G AR P + + S++ I +LL G L
Sbjct: 317 EVIEETRIPQPYRLNHV--------LGNIFNRLGGICARFPGLTITSTIVISLLLSLGWL 368
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN 438
RF VET P +LWV P S AA+EKE++DS+ PFYRIEQ+ + + + + G+P ++ +
Sbjct: 369 RFAVETDPVRLWVSPTSAAAQEKEYYDSNFEPFYRIEQVFV--VKDVDTGEPEPVLNYET 426
Query: 439 IELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYF-----QMDPDNFDN 493
+ F+++ +V + + L +L D+C P G C QS+ YF ++PD + +
Sbjct: 427 LGWWFDVENRVRRMISLKKRL--TLDDVCFNPTGHACVVQSLSGYFGGSFANVNPDTWQS 484
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-NNYSEASAFIITYPVNNALT 552
H ++C Q S + C F+ PL P LGGF+ N +A + IIT+ VNN
Sbjct: 485 -----HLQHCAQSPGSRD-CLPDFQQPLAPEMVLGGFNDTTNILDARSLIITWVVNN-FE 537
Query: 553 KVGDENGKAIAWEKAFIQLAKV 574
+ D+ +A+ WE+ Q+ +V
Sbjct: 538 QGSDKEARAMDWEETLKQVLQV 559
>R8BD46_9PEZI (tr|R8BD46) Putative patched sphingolipid transporter protein
OS=Togninia minima UCRPA7 GN=UCRPA7_7312 PE=4 SV=1
Length = 1274
Score = 252 bits (644), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 169/549 (30%), Positives = 263/549 (47%), Gaps = 42/549 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLC-PTIT-GNVCCTEEQ 93
H CA+ CG + GK L C P+ +P + L ++ LC P G VCC EQ
Sbjct: 29 HEAGRCAIRGHCGSKGFFGKQLPCVDNGPAEEPDESLRQQLVDLCGPKWNDGPVCCNAEQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLFIN+T + + V +D
Sbjct: 89 VKSLKSELSTANQIISSCPACKENFYNLFCSFTCSPDQSLFINITKTMEKNKKTLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E +G G Y +CKDVKFG N +A+DF+G GA NY + FLG + G SP+ I
Sbjct: 149 QLISEEYGTGFYDSCKDVKFGPSNAKAMDFIGGGATNYSGFLKFLGDEKAIG---SPFQI 205
Query: 206 DFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGS 264
+F S P M +C+D + GS
Sbjct: 206 NFPKKY--SEPGMAPTGMKPKACSDPDFRCACVDCPAVCPELPAVK----------ERGS 253
Query: 265 LKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKD 321
+V C+ + +Y VL F G + S E L + + + ++ +
Sbjct: 254 CRVGVLPCLSFASIFVYSVLAFSFIGAVVGHVAWKKHAQRRS-ERLRLLQDSTASDDEDE 312
Query: 322 GEVLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
G+ LV +P + ++ I W + G WAAR P I + +SL IV++L G +RF
Sbjct: 313 GD-LVHNPAMLDRPTKAYRINTWCDAAFFKLGHWAARFPAITVFTSLLIVVVLSLGWIRF 371
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIE 440
++E P +LWV P S AA+EK FFD + PFYR E+L + +++ P +++ D I
Sbjct: 372 DIEKDPARLWVSPTSAAAQEKAFFDDNFGPFYRAEKLFLVN--DTQPSGPGPVLSYDTII 429
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHA 500
++++ + +++ G +L D+CLKP G C QS+ YF+ +P +
Sbjct: 430 WWMDVEKSIKQLKGPKFG--ATLGDVCLKPTGSACVVQSVAAYFENEPALVGKNSWKDDL 487
Query: 501 EYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDENG 559
+C Q S C + PL+P LGG+ + +EA+A +T+ VNN + E
Sbjct: 488 RHCAQ---SPVDCRPEYGQPLDPGMILGGYPKSGDVAEATAMTVTWVVNN-FPEGTSEVA 543
Query: 560 KAIAWEKAF 568
+A+ WE+A
Sbjct: 544 RAMDWEEAL 552
>G2QH84_THIHA (tr|G2QH84) Uncharacterized protein OS=Thielavia heterothallica
(strain ATCC 42464 / BCRC 31852 / DSM 1799)
GN=MYCTH_2306273 PE=4 SV=1
Length = 1276
Score = 252 bits (644), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 175/586 (29%), Positives = 271/586 (46%), Gaps = 49/586 (8%)
Query: 1 MENMSTAIISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNC 59
M + + S G LL L AA + H CA+ CG +S G L C
Sbjct: 1 MTKLPGLVASGGLLLTTL-------GSVAADVYTPKHEAGRCAIRGHCGSKSFFGSQLPC 53
Query: 60 PYPSPSVKPHDLLSAKIQSLC--PTITGNVCCTEEQLQAVP--------ILVGCPACLRN 109
+ +P L ++ LC G VCCT EQ+ A+ I+ CPAC N
Sbjct: 54 VDNGLAEEPDAKLRGQLVELCGPKWAQGPVCCTAEQVDALKSNLQTANQIISTCPACKDN 113
Query: 110 FLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMN 169
F N+FC +CSP+QSLFINVT + +G V +D ++E +G G Y++CKDVKFG N
Sbjct: 114 FYNMFCTFTCSPDQSLFINVTKTMEKNGKTLVRELDQLISEEYGSGFYNSCKDVKFGPTN 173
Query: 170 TRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS--PMELMNASVYSC 227
+RA+D +G GA N+ + FLGQ+ F GSP+ I+F T+ + + P+E+ + C
Sbjct: 174 SRAMDLIGGGAKNHAQLLKFLGQE---RFGGSPFQINFPTSYPEENMGPLEM---TPKKC 227
Query: 228 NDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFG 287
ND +G+L C+ + + Y V +FV
Sbjct: 228 NDED---PSFRCACIDCPQVCPKLPAVKEEGSCHVGALP--CLSFASILTYGVALFVFLA 282
Query: 288 WIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGE---VLVIDPQRQNEVQYSFI-QEW 343
+ S L+++ P D E L + + + ++I W
Sbjct: 283 AVVGRFVWTRHAKRRSERLRLLTDA-----TPSDDEDEGYLTQNGAMFDRPRNAYIVNTW 337
Query: 344 LSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEF 403
+ G AAR P + + +S +V+LL FG F +E P +LWV P S+AA+EK F
Sbjct: 338 CDAAFSRLGHTAARFPALTIATSTLVVLLLSFGWFHFEIEKDPARLWVSPTSEAAQEKAF 397
Query: 404 FDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSL 463
FD + PFYR E++ + + P +++ D + +++ + +R + G +L
Sbjct: 398 FDENFGPFYRTEKIFLVN--DLNASAPGPVLSYDTLLWWIDVEASIRNLRGSKYG--STL 453
Query: 464 SDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEP 523
D+CLKP G+ C QS+ YF DP+ D +G C S C + PLEP
Sbjct: 454 QDLCLKPAGDACVVQSVAAYFHNDPEEVDRHGWKAKLRECAD---SPVGCRPEYGQPLEP 510
Query: 524 TTALGGFS-GNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
LGG+S + ++A+A +T+ +NN + E +A+ WE+A
Sbjct: 511 NMILGGYSESGDPADATAMTVTWVLNN-YPEGSPEAARAMDWEEAM 555
>R0K538_SETTU (tr|R0K538) Uncharacterized protein OS=Setosphaeria turcica Et28A
GN=SETTUDRAFT_176752 PE=4 SV=1
Length = 1271
Score = 252 bits (644), Expect = 3e-64, Method: Compositional matrix adjust.
Identities = 166/547 (30%), Positives = 251/547 (45%), Gaps = 30/547 (5%)
Query: 15 LQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLS 73
+ V +LS + S A + H CAM CG++ G L CP P+ P D +
Sbjct: 12 MTVGLLSVLAGSALAGPDLTTRHEKGRCAMRGQCGKQGFFGSELPCPDNGPAKTPDDAVR 71
Query: 74 AKIQSLCPT--ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQ 123
K+ +C ++CC E QL +A PI+ CPAC NF NLFC +CSP+Q
Sbjct: 72 KKLVDICGAQWSDTDICCEENQLDALKTNLDRATPIINACPACKENFFNLFCTFTCSPDQ 131
Query: 124 SLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNY 183
S FIN+T V +D V E + Y +CKDVKFG N +A+DF+G GA NY
Sbjct: 132 STFINITGTEPKGDKYLVTELDNLVAEKYASTFYDSCKDVKFGATNGKAMDFIGGGATNY 191
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXX 242
++ FLG K F GSP+ I+F D P M M+ Y C DT
Sbjct: 192 TQFLKFLGDK---KFLGSPFQINFPPPSEDRFPGMTAMSKHAYPC-DTDDEKYRCACLDC 247
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGS 302
+ + + C+ S+ V+Y + +L +
Sbjct: 248 GTSCTELPAVQEGKQCYVGL----LPCLSFSVIVIYSCFLGLLCTAVAGHVAYQKHSKHK 303
Query: 303 SAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV 362
S E + + + S ++ +G+++ ++ F+ W + G AR P I
Sbjct: 304 S-ERMRLLQDTSPSDDEDEGDIVHNIGMLDRPTKHYFVNTWCDRLFSRLGYVCARFPAIT 362
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATL 422
+ +S+ VIL+ G LRF +ET P LWV P+S AA+EK FFD PF+R EQ A L
Sbjct: 363 IVTSVMAVILMSLGWLRFQIETDPVNLWVAPDSAAAQEKAFFDEKFGPFFRAEQ---AFL 419
Query: 423 PESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQ 482
H +++ + ++ F ++ ++ +++ G V+L DIC KP+G+DC QS+
Sbjct: 420 VNDTHKGAGPVLSYETLDWWFGVENQIQRLKSAEHG--VTLDDICFKPVGDDCVIQSVTG 477
Query: 483 YFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFI 542
YFQ D F N + Q + C F+ PL+P GG + + +A A +
Sbjct: 478 YFQGD---FANVVPDSWQDDLLQCVDNPTQCLPTFQQPLDPHLLFGGVN-QSVLDAKALV 533
Query: 543 ITYPVNN 549
+T+ V N
Sbjct: 534 VTWVVKN 540
>G4UZ74_NEUT9 (tr|G4UZ74) Multidrug efflux transporter AcrB transmembrane
domain-containing protein OS=Neurospora tetrasperma
(strain FGSC 2509 / P0656) GN=NEUTE2DRAFT_152704 PE=4
SV=1
Length = 1279
Score = 248 bits (633), Expect = 5e-63, Method: Compositional matrix adjust.
Identities = 173/560 (30%), Positives = 258/560 (46%), Gaps = 48/560 (8%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
A+I H CA+ CG + G L C + +P D L ++ LC TG
Sbjct: 24 AEIYTPKHEAGRCAIRGHCGSKGLFGSQLPCVDNGLAEEPDDYLRQQLVDLCGPKWSTGP 83
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC EQ+ ++ I+ CPAC NF N+FC +CSPNQSLF+NVT + G
Sbjct: 84 VCCLPEQVDSLKSSLSTVNQIISSCPACKDNFFNMFCTFTCSPNQSLFVNVTKTIEKKGK 143
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
V +D ++E +G G Y++CKDVKFG N+RA+D +G GA NY + FLGQ+ F
Sbjct: 144 ELVTELDQLISEEYGTGFYNSCKDVKFGPTNSRAMDLIGGGAKNYTQLLKFLGQE---RF 200
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
GSP+ I+F + M+ + CND
Sbjct: 201 GGSPFQINFPVEYAEPD-MKPLPMKPKKCNDED---PNFRCACVDCPEICPTLPDVEQAG 256
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
+G+L C+ + + Y V++F+ + S L+++
Sbjct: 257 SCHVGALP--CLSFASILTYSVILFISIAAVVGHIAWKRHAKRRSERLRLLTDAA----- 309
Query: 319 PKDGE--------VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
P D E V +ID ++ + I W + + G AA P I + +S+ I
Sbjct: 310 PSDDEDEGDLTQNVAMIDRPQKTYI----INTWCDSAFSKLGYIAATFPAITIVTSILIA 365
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+L G F +E P +LWV P S AAEEK FFDSH FYR E++ + ++ P
Sbjct: 366 SVLSLGWFHFELEKNPARLWVSPTSPAAEEKAFFDSHFGAFYRAEKVFLVN--DTNPSGP 423
Query: 431 PSIVTDDNIELLFEIQEKVDEIR-ANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPD 489
+++ D + ++++ V ++ ANY S D+CLKP G+ C QS+ YFQ DPD
Sbjct: 424 GPVLSRDTLLWWMDVEKSVAALKGANYGS---SFQDLCLKPTGDACVVQSVAAYFQDDPD 480
Query: 490 NFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVN 548
+ D C S C A+ PL+P+ LGG+ G N +EASA +T+ +
Sbjct: 481 SVDPETWQSTLRTC---AASPVECRPAYGQPLDPSMILGGYPEGGNVAEASAMTVTWVLI 537
Query: 549 NALTKVGDENGKAIAWEKAF 568
N + E +A+ WE A
Sbjct: 538 NP-PENSPEVDRAMDWEVAL 556
>F8MXC7_NEUT8 (tr|F8MXC7) Putative uncharacterized protein OS=Neurospora
tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657)
GN=NEUTE1DRAFT_148735 PE=4 SV=1
Length = 1279
Score = 248 bits (633), Expect = 5e-63, Method: Compositional matrix adjust.
Identities = 173/560 (30%), Positives = 258/560 (46%), Gaps = 48/560 (8%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
A+I H CA+ CG + G L C + +P D L ++ LC TG
Sbjct: 24 AEIYTPKHEAGRCAIRGHCGSKGLFGSQLPCVDNGLAEEPDDYLRQQLVDLCGPKWSTGP 83
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC EQ+ ++ I+ CPAC NF N+FC +CSPNQSLF+NVT + G
Sbjct: 84 VCCLPEQVDSLKSSLSTVNQIISSCPACKDNFFNMFCTFTCSPNQSLFVNVTKTIEKKGK 143
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
V +D ++E +G G Y++CKDVKFG N+RA+D +G GA NY + FLGQ+ F
Sbjct: 144 ELVTELDQLISEEYGTGFYNSCKDVKFGPTNSRAMDLIGGGAKNYTQLLKFLGQE---RF 200
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
GSP+ I+F + M+ + CND
Sbjct: 201 GGSPFQINFPVEYAEPD-MKPLPMKPKKCNDED---PNFRCACVDCPEICPTLPDVEQAG 256
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
+G+L C+ + + Y V++F+ + S L+++
Sbjct: 257 SCHVGALP--CLSFASILTYSVILFISIAAVVGHIAWKRHAKRRSERLRLLTDAA----- 309
Query: 319 PKDGE--------VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
P D E V +ID ++ + I W + + G AA P I + +S+ I
Sbjct: 310 PSDDEDEGDLTQNVAMIDRPQKTYI----INTWCDSAFSKLGYIAATFPAITIVTSILIA 365
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+L G F +E P +LWV P S AAEEK FFDSH FYR E++ + ++ P
Sbjct: 366 SVLSLGWFHFELEKNPARLWVSPTSPAAEEKAFFDSHFGAFYRAEKVFLVN--DTNPSGP 423
Query: 431 PSIVTDDNIELLFEIQEKVDEIR-ANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPD 489
+++ D + ++++ V ++ ANY S D+CLKP G+ C QS+ YFQ DPD
Sbjct: 424 GPVLSRDTLLWWMDVEKSVAALKGANYGS---SFQDLCLKPTGDACVVQSVAAYFQDDPD 480
Query: 490 NFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVN 548
+ D C S C A+ PL+P+ LGG+ G N +EASA +T+ +
Sbjct: 481 SVDPETWQSTLRTC---AASPVECRPAYGQPLDPSMILGGYPEGGNVAEASAMTVTWVLI 537
Query: 549 NALTKVGDENGKAIAWEKAF 568
N + E +A+ WE A
Sbjct: 538 NP-PENSPEVDRAMDWEVAL 556
>B0Y842_ASPFC (tr|B0Y842) Patched sphingolipid transporter (Ncr1), putative
OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 /
FGSC A1163) GN=AFUB_076030 PE=4 SV=1
Length = 1273
Score = 248 bits (632), Expect = 7e-63, Method: Compositional matrix adjust.
Identities = 180/574 (31%), Positives = 269/574 (46%), Gaps = 49/574 (8%)
Query: 19 ILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQ 77
+LS+ +L A+ IH CA+ CG++S G L CP P+ +P K+
Sbjct: 15 LLSFLPRTLVVAEGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNGPAREPEVSTRKKLV 74
Query: 78 SLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFI 127
+LC + G+VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLFI
Sbjct: 75 NLCGSKWNEGSVCCEDEQIDALAKNLKLAEGIIASCPACKANFFNIFCTFTCSPDQSLFI 134
Query: 128 NVTSISQVD-GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEW 186
NVT G + V +D +E + G Y +CK+VK G +A+DF+G GA NY ++
Sbjct: 135 NVTQTEMASSGKLLVTELDNIWSEEYQSGFYDSCKNVKNGASGGKAVDFIGGGAKNYTQF 194
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNA---SVYSCNDTSLGXXXXXXXXXX 243
FLG K GSP+ I++KT SSP + M A +CND
Sbjct: 195 LKFLGDK---KLLGSPFQINYKTE--PSSPDQGMRALPIKPKACNDPD---EAFRCSCVD 246
Query: 244 XXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSS 303
+G L LS AV+ I VF+L
Sbjct: 247 CPEVCPELPEVKTDKSCHVGLLPC----LSFAVILIYSVFLLAVVAFSSYFTYRERRYRK 302
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVL 363
E + + + S + +G+++ + + L + + + G AR P I +
Sbjct: 303 PERVRLLQDPSPDDSEDEGDIVHAAGSLEQPSGVYKLNSMLDSMFNSIGSTCARFPAITI 362
Query: 364 CSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLP 423
+S+ +V LL G LRF VET P +LWV P S AA+EKE+FD++ PFYR EQ+ +
Sbjct: 363 VTSILLVGLLSLGWLRFAVETDPVRLWVSPTSPAAQEKEYFDANFGPFYRAEQVFVV--- 419
Query: 424 ESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQY 483
+EHG ++T D + F+++ ++ + + GLL L D+C KP G+ C QS+ Y
Sbjct: 420 -NEHGP---VLTYDTLSWWFDVESQIRRMISPGRGLL--LDDVCFKPTGDACVVQSLTGY 473
Query: 484 F-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSE 537
F + PD ++ E ++C + +C F+ PL+P LGG+ N
Sbjct: 474 FGGSGWNLHPDTWE-----ERIKHC-ANSPGDPSCLPDFQQPLKPEMILGGYEKSGNVLH 527
Query: 538 ASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
A A I T+ +NN E AI WE QL
Sbjct: 528 AQALITTWVLNNHAQGTEGE-ADAIDWENNLKQL 560
>Q4WMG5_ASPFU (tr|Q4WMG5) Patched sphingolipid transporter (Ncr1), putative
OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 /
CBS 101355 / FGSC A1100) GN=AFUA_6G09980 PE=4 SV=1
Length = 1273
Score = 248 bits (632), Expect = 7e-63, Method: Compositional matrix adjust.
Identities = 180/574 (31%), Positives = 269/574 (46%), Gaps = 49/574 (8%)
Query: 19 ILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQ 77
+LS+ +L A+ IH CA+ CG++S G L CP P+ +P K+
Sbjct: 15 LLSFLPRTLVVAEGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNGPAREPEVSTRKKLV 74
Query: 78 SLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFI 127
+LC + G+VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLFI
Sbjct: 75 NLCGSKWNEGSVCCEDEQIDALAKNLKLAEGIIASCPACKANFFNIFCTFTCSPDQSLFI 134
Query: 128 NVTSISQVD-GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEW 186
NVT G + V +D +E + G Y +CK+VK G +A+DF+G GA NY ++
Sbjct: 135 NVTQTEMASSGKLLVTELDNIWSEEYQSGFYDSCKNVKNGASGGKAVDFIGGGAKNYTQF 194
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNA---SVYSCNDTSLGXXXXXXXXXX 243
FLG K GSP+ I++KT SSP + M A +CND
Sbjct: 195 LKFLGDK---KLLGSPFQINYKTE--PSSPDQGMRALPIKPKACNDPD---EAFRCSCVD 246
Query: 244 XXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSS 303
+G L LS AV+ I VF+L
Sbjct: 247 CPEVCPELPEVKTDKSCHVGLLPC----LSFAVILIYSVFLLAVVAFSSYFTYRERRYRK 302
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVL 363
E + + + S + +G+++ + + L + + + G AR P I +
Sbjct: 303 PERVRLLQDPSPDDSEDEGDIVHAAGSLEQPSGVYKLNSMLDSMFNSIGSTCARFPAITI 362
Query: 364 CSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLP 423
+S+ +V LL G LRF VET P +LWV P S AA+EKE+FD++ PFYR EQ+ +
Sbjct: 363 VTSILLVGLLSLGWLRFAVETDPVRLWVSPTSPAAQEKEYFDANFGPFYRAEQVFVV--- 419
Query: 424 ESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQY 483
+EHG ++T D + F+++ ++ + + GLL L D+C KP G+ C QS+ Y
Sbjct: 420 -NEHGP---VLTYDTLSWWFDVESQIRRMISPGRGLL--LDDVCFKPTGDACVVQSLTGY 473
Query: 484 F-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSE 537
F + PD ++ E ++C + +C F+ PL+P LGG+ N
Sbjct: 474 FGGSGWNLHPDTWE-----ERIKHC-ANSPGDPSCLPDFQQPLKPEMILGGYEKSGNVLH 527
Query: 538 ASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
A A I T+ +NN E AI WE QL
Sbjct: 528 AQALITTWVLNNHAQGTEGE-ADAIDWENNLKQL 560
>L7J8J1_MAGOR (tr|L7J8J1) Niemann-Pick C1 protein OS=Magnaporthe oryzae P131
GN=OOW_P131scaffold00602g3 PE=4 SV=1
Length = 1275
Score = 247 bits (631), Expect = 8e-63, Method: Compositional matrix adjust.
Identities = 168/551 (30%), Positives = 261/551 (47%), Gaps = 44/551 (7%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG++S GK L C P+ P + + LC TG VCC + Q
Sbjct: 29 HEAGRCAMRGHCGKKSWFGKELPCVDNGPAENPDEDFRKLLVDLCGPKWETGPVCCDKSQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+NVT + +G + + +D
Sbjct: 89 VESLKSELSTPRQIVSSCPACKDNFYNLFCTFTCSPDQSLFVNVTKAQEKNGKLQITELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++ +G G Y +CKDVKFG N++A+DF+G GA NY + FLG + GSP+ I
Sbjct: 149 QLISSEYGTGFYDSCKDVKFGPSNSKAMDFIGGGAKNYTQLLKFLGDEKA---IGSPFQI 205
Query: 206 DFKTTILDS--SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
+F T + SP E+ CND +G
Sbjct: 206 NFPTEYSEPAMSPREMKPK---RCNDDD---PNFRCACVDCPQVCPELPAVKESGSCHVG 259
Query: 264 SLKVRCVDLSLAVLYIVLVFVLF-----GWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
SL C+ + Y +++F L G++ + + S+ +L
Sbjct: 260 SLP--CLSFAAIFTYSIILFSLAVALTGGFVLKKHNERRRERLRLLQDPVRSDDEDEGDL 317
Query: 319 PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
+ +L PQ V W + + G AAR P I + SSL IV +L GL
Sbjct: 318 VHNNAML-DRPQSNYPV-----NSWCDSAFSKLGHTAARFPGITIISSLIIVAVLSLGLF 371
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN 438
RF++E P +LWV P S AA+EK FFD++ PFYR E++ + ++ P +++ DN
Sbjct: 372 RFDIEKDPARLWVSPTSAAAQEKAFFDANFGPFYRAEKIFLVN--DTNPSSPGPVLSYDN 429
Query: 439 IELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVE 498
+ +++ V +++ G + L D+CLKP G C QS+ YF D DN G
Sbjct: 430 LIWWIDVENSVKQLKGPRFGAM--LQDVCLKPTGSACVVQSVAAYFGNDADNVSKGGWKG 487
Query: 499 HAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDE 557
+ C + S C F P++P LGG+ +G++ ++A A +T+ +NN + E
Sbjct: 488 NLRDCAR---SPVECRPDFGQPIDPGMILGGYGAGDDIADAQAMTVTWVLNN-FPEGTSE 543
Query: 558 NGKAIAWEKAF 568
+A+ +E+A
Sbjct: 544 EARAMDFEEAL 554
>L7HPU7_MAGOR (tr|L7HPU7) Niemann-Pick C1 protein OS=Magnaporthe oryzae Y34
GN=OOU_Y34scaffold01007g3 PE=4 SV=1
Length = 1275
Score = 247 bits (631), Expect = 8e-63, Method: Compositional matrix adjust.
Identities = 168/551 (30%), Positives = 261/551 (47%), Gaps = 44/551 (7%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG++S GK L C P+ P + + LC TG VCC + Q
Sbjct: 29 HEAGRCAMRGHCGKKSWFGKELPCVDNGPAENPDEDFRKLLVDLCGPKWETGPVCCDKSQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+NVT + +G + + +D
Sbjct: 89 VESLKSELSTPRQIVSSCPACKDNFYNLFCTFTCSPDQSLFVNVTKAQEKNGKLQITELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++ +G G Y +CKDVKFG N++A+DF+G GA NY + FLG + GSP+ I
Sbjct: 149 QLISSEYGTGFYDSCKDVKFGPSNSKAMDFIGGGAKNYTQLLKFLGDEKA---IGSPFQI 205
Query: 206 DFKTTILDS--SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
+F T + SP E+ CND +G
Sbjct: 206 NFPTEYSEPAMSPREMKPK---RCNDDD---PNFRCACVDCPQVCPELPAVKESGSCHVG 259
Query: 264 SLKVRCVDLSLAVLYIVLVFVLF-----GWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
SL C+ + Y +++F L G++ + + S+ +L
Sbjct: 260 SLP--CLSFAAIFTYSIILFSLAVALTGGFVLKKHNERRRERLRLLQDPVRSDDEDEGDL 317
Query: 319 PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
+ +L PQ V W + + G AAR P I + SSL IV +L GL
Sbjct: 318 VHNNAML-DRPQSNYPV-----NSWCDSAFSKLGHTAARFPGITIISSLIIVAVLSLGLF 371
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN 438
RF++E P +LWV P S AA+EK FFD++ PFYR E++ + ++ P +++ DN
Sbjct: 372 RFDIEKDPARLWVSPTSAAAQEKAFFDANFGPFYRAEKIFLVN--DTNPSSPGPVLSYDN 429
Query: 439 IELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVE 498
+ +++ V +++ G + L D+CLKP G C QS+ YF D DN G
Sbjct: 430 LIWWIDVENSVKQLKGPRFGAM--LQDVCLKPTGSACVVQSVAAYFGNDADNVSKGGWKG 487
Query: 499 HAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDE 557
+ C + S C F P++P LGG+ +G++ ++A A +T+ +NN + E
Sbjct: 488 NLRDCAR---SPVECRPDFGQPIDPGMILGGYGAGDDIADAQAMTVTWVLNN-FPEGTSE 543
Query: 558 NGKAIAWEKAF 568
+A+ +E+A
Sbjct: 544 EARAMDFEEAL 554
>G4NE97_MAGO7 (tr|G4NE97) Niemann-Pick C1 protein OS=Magnaporthe oryzae (strain
70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_00819 PE=4
SV=1
Length = 1275
Score = 247 bits (631), Expect = 8e-63, Method: Compositional matrix adjust.
Identities = 168/551 (30%), Positives = 261/551 (47%), Gaps = 44/551 (7%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG++S GK L C P+ P + + LC TG VCC + Q
Sbjct: 29 HEAGRCAMRGHCGKKSWFGKELPCVDNGPAENPDEDFRKLLVDLCGPKWETGPVCCDKSQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+NVT + +G + + +D
Sbjct: 89 VESLKSELSTPRQIVSSCPACKDNFYNLFCTFTCSPDQSLFVNVTKAQEKNGKLQITELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++ +G G Y +CKDVKFG N++A+DF+G GA NY + FLG + GSP+ I
Sbjct: 149 QLISSEYGTGFYDSCKDVKFGPSNSKAMDFIGGGAKNYTQLLKFLGDEKA---IGSPFQI 205
Query: 206 DFKTTILDS--SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
+F T + SP E+ CND +G
Sbjct: 206 NFPTEYSEPAMSPREMKPK---RCNDDD---PNFRCACVDCPQVCPELPAVKESGSCHVG 259
Query: 264 SLKVRCVDLSLAVLYIVLVFVLF-----GWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
SL C+ + Y +++F L G++ + + S+ +L
Sbjct: 260 SLP--CLSFAAIFTYSIILFSLAVALTGGFVLKKHNERRRERLRLLQDPVRSDDEDEGDL 317
Query: 319 PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
+ +L PQ V W + + G AAR P I + SSL IV +L GL
Sbjct: 318 VHNNAML-DRPQSNYPV-----NSWCDSAFSKLGHTAARFPGITIISSLIIVAVLSLGLF 371
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN 438
RF++E P +LWV P S AA+EK FFD++ PFYR E++ + ++ P +++ DN
Sbjct: 372 RFDIEKDPARLWVSPTSAAAQEKAFFDANFGPFYRAEKIFLVN--DTNPSSPGPVLSYDN 429
Query: 439 IELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVE 498
+ +++ V +++ G + L D+CLKP G C QS+ YF D DN G
Sbjct: 430 LIWWIDVENSVKQLKGPRFGAM--LQDVCLKPTGSACVVQSVAAYFGNDADNVSKGGWKG 487
Query: 499 HAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDE 557
+ C + S C F P++P LGG+ +G++ ++A A +T+ +NN + E
Sbjct: 488 NLRDCAR---SPVECRPDFGQPIDPGMILGGYGAGDDIADAQAMTVTWVLNN-FPEGTSE 543
Query: 558 NGKAIAWEKAF 568
+A+ +E+A
Sbjct: 544 EARAMDFEEAL 554
>G0SAS3_CHATD (tr|G0SAS3) Hedgehog receptor-like protein OS=Chaetomium
thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
GN=CTHT_0043300 PE=4 SV=1
Length = 1313
Score = 246 bits (629), Expect = 1e-62, Method: Compositional matrix adjust.
Identities = 173/591 (29%), Positives = 267/591 (45%), Gaps = 49/591 (8%)
Query: 1 MENMSTAIISVGFLLQVLILSWFSPSLTAAQISRSI-----HSNEYCAMYDICGQRSD-G 54
M N+ ++S G L + SP + A+ ++ H CA+ CG +S G
Sbjct: 1 MTNLPALLLSGGLFLTTAL----SPLVAASSAPETMLLTPKHEAGRCAVRHNCGSKSFFG 56
Query: 55 KVLNCPYPSPSVKPHDLLSAKIQSLC--PTITGNVCCTEEQLQ--------AVPILVGCP 104
L C P+ +P D L ++ LC G VCC +Q+ A I+ CP
Sbjct: 57 PQLPCVDNGPAHEPDDALRQQLVELCGPKWAEGPVCCDADQVDTLRGNLKTANQIIASCP 116
Query: 105 ACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVK 164
AC NF N+FC +CSP+QSLFINVT + G + V +D +++ +GEG Y +CKDVK
Sbjct: 117 ACKENFYNMFCTFTCSPDQSLFINVTKAIEKGGKLLVTELDQLISKDYGEGFYDSCKDVK 176
Query: 165 FGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDF-KTTILDSSPMELMNAS 223
FG N+RA+D +G GA NY + FLGQ+ F GSP+ I+F M +
Sbjct: 177 FGPTNSRAMDLIGGGARNYTQLLRFLGQE---RFGGSPFQINFPDPETYPERSMSPLPMK 233
Query: 224 VYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIV 280
CND K GS V C+ + + Y +
Sbjct: 234 PKKCNDEDPAFRCACIDCPAVCPELPAVE--------KAGSCHVGRLPCLSFASILTYSL 285
Query: 281 LVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFI 340
++ + F + L+++ + + D +VL + R + +
Sbjct: 286 VLLLTFAAMAIRAAWKRHTKRRGERLRLLADATASEDEDDDRDVLG-NRIRPPPAKTYVL 344
Query: 341 QEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEE 400
W + G AAR P + + + + IV++L G F +E P +LWV P S AA+E
Sbjct: 345 NTWCDTAFSRLGHTAARFPALTISTCVLIVMILSAGWFHFEIEKDPARLWVSPTSAAAQE 404
Query: 401 KEFFDSHLAPFYRIEQLIIA--TLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSG 458
K FFD + PFYR E++ + TLP P +++ + I +++ + ++ G
Sbjct: 405 KAFFDENFGPFYRSEKIFLVNDTLPSG----PGPVLSYETIVWWMSVEQSIRALKGPKFG 460
Query: 459 LLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFK 518
+L D+C KP G+ C QS+ YFQ DPD D + + C + S C A+
Sbjct: 461 --STLQDLCFKPTGDACVVQSVAAYFQDDPDFVDPWTWKDTLRECAE---SPVNCRPAYG 515
Query: 519 APLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
PLEP LGG+ G + EA+A +T+ + N + E +A+ WE A
Sbjct: 516 QPLEPNMILGGYPEGGDPVEATAMTVTWVLRN-YAEGSYETTRAMDWEAAL 565
>B6HDY6_PENCW (tr|B6HDY6) Pc20g15300 protein (Precursor) OS=Penicillium
chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin
54-1255) GN=Pc20g15300 PE=4 SV=1
Length = 1275
Score = 246 bits (628), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 176/592 (29%), Positives = 266/592 (44%), Gaps = 81/592 (13%)
Query: 17 VLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAK 75
++ L F+P+L AQ IH CA+ CG++S G L CP + +P D + K
Sbjct: 10 IVGLGSFAPTLVGAQGETRIHEKGRCAIRGHCGKQSIFGGELPCPDNDLAQQPEDAVRQK 69
Query: 76 IQSLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSL 125
+ +LC + G VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSL
Sbjct: 70 LVNLCGSKWSEGPVCCLDEQIDALSSNLKLAEGIIASCPACRDNFFNIFCTFTCSPDQSL 129
Query: 126 FINVTSISQ-VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYK 184
F+NVT + G V +D +E + G + +CK VK G +AIDF+G GA ++
Sbjct: 130 FVNVTKTEESSSGKRRVTELDNVWSEEYQSGFFDSCKHVKNGASGGKAIDFIGGGAKDHT 189
Query: 185 EWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXX 242
+ FLG K F GSP+ I++ S P ME ++ +CND
Sbjct: 190 HFMKFLGDK---KFLGSPFQINYHAEPSGSDPQGMEALSIKPKACNDED----------- 235
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVD------------------------LSLAVLY 278
S + CVD LS AV+
Sbjct: 236 --------------------KSFRCSCVDCPDVCPELPAISPHEVCHVGLLPCLSFAVIL 275
Query: 279 IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYS 338
+ +F+LF E + + + + ++ +GEV+ +
Sbjct: 276 VYSIFLLFVIALASYFTYKERRFRKPERVRLLQDPTPSDDEDEGEVMHHGGYMEQSQGVY 335
Query: 339 FIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAA 398
+ LS + G AR P I + +S+ V LL G L F VET P +LWV P S AA
Sbjct: 336 KLNSVLSALFHRIGGACARFPAITISASVIGVTLLSLGWLSFAVETDPVRLWVSPSSAAA 395
Query: 399 EEKEFFDSHLAPFYRIEQ-LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYS 457
+EK+FFD PFYR EQ ++ PE++ +P ++ + + F+++ +V + +
Sbjct: 396 QEKDFFDQSFGPFYRAEQAFLVNNRPEND-SRP--LLDYETLTWWFDVESRVRRVIS--L 450
Query: 458 GLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAF 517
G ++ D+C KP GE C QS+ YF N D + +C + +C F
Sbjct: 451 GQSLNFDDVCFKPTGEACVVQSVTGYFGGSVSNLDPDTWKDRLSHCTES-PGDPSCLPDF 509
Query: 518 KAPLEPTTALGGFSGN-NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
PL+P LGG+ N +A A I+T+ VNN + +E KAI WE F
Sbjct: 510 SQPLKPEMILGGYDDTGNVLDAQALIVTWVVNN-YAQGTEEEAKAIDWENTF 560
>Q5BBG1_EMENI (tr|Q5BBG1) Putative uncharacterized protein OS=Emericella nidulans
(strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
M139) GN=AN2119.2 PE=4 SV=1
Length = 1271
Score = 246 bits (628), Expect = 2e-62, Method: Compositional matrix adjust.
Identities = 176/564 (31%), Positives = 259/564 (45%), Gaps = 31/564 (5%)
Query: 25 PSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI 83
P+ + AQ IH N CA+ CG++S G L CP + +P + K+ +LC
Sbjct: 16 PAHSFAQGKTRIHENGRCAIRGHCGKQSFFGGELPCPDNDAAREPEAAVREKLVNLCGAK 75
Query: 84 --TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS 133
G VCC EEQ+ A+ I+ CPAC NF N+FC +CSP+QSLFINVT
Sbjct: 76 WQEGPVCCEEEQIDALSKNLKLAEGIISSCPACKDNFFNIFCTFTCSPDQSLFINVTKTE 135
Query: 134 QVD-GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQ 192
+ + G V +D +E + G Y +CK+VK G +AIDF+G GA +Y+++ FLG
Sbjct: 136 KGNSGKELVTELDNIWSEEYQSGFYDSCKNVKNGASGGKAIDFIGGGAKDYQQFLKFLGD 195
Query: 193 KVPPGFPGSPYSIDFKTT-ILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
K F GSP+ I++ T DS M+ + +CND
Sbjct: 196 K---KFLGSPFQINYHTEPPEDSQGMQALPIHPKACNDAD---PAYRCSCVDCPDVCPEL 249
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSE 311
+G L C+ S+ ++Y V + + G+ LL
Sbjct: 250 PAIKTEEHCHVGLLP--CLSFSVILIYSVFLLGVAGFSSYFTYRERRYRKPERVRLLQDP 307
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
S + +G+++ + Y + L + G AR P + + SS+ V+
Sbjct: 308 NPS--DDEDEGDIVHAGGHLEYPHGYYKLNSMLDTVFSRIGSVCARFPALTIISSVVAVV 365
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
LL G LRF VET P +LWV P S AA+EK FFD + PFYR EQ + E+ G+
Sbjct: 366 LLSLGWLRFAVETDPVRLWVSPTSAAAKEKAFFDENFGPFYRAEQAFLVNDDETGDGR-- 423
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
++ D + F ++ ++ + + GL SL DIC KP G+ C QS+ YF N
Sbjct: 424 -VLDYDTLTWWFGVESRIRRVISLDRGL--SLDDICYKPTGDACVIQSVTGYFGGSLSNL 480
Query: 492 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNA 550
D + +C +C F PL P LGG+ N +A A I+T+ VNN
Sbjct: 481 DPDTWQDRLTHCASS-PGDASCLPDFSQPLRPEMILGGYEDSGNVLDAKALIVTWVVNNH 539
Query: 551 LTKVGDENGKAIAWEKAFIQLAKV 574
+E +AI WE F + +V
Sbjct: 540 APG-SEEEAEAIDWEDTFRGIFQV 562
>B2W9M2_PYRTR (tr|B2W9M2) Niemann-Pick C1 protein OS=Pyrenophora tritici-repentis
(strain Pt-1C-BFP) GN=PTRG_06680 PE=4 SV=1
Length = 1265
Score = 245 bits (625), Expect = 4e-62, Method: Compositional matrix adjust.
Identities = 155/525 (29%), Positives = 247/525 (47%), Gaps = 30/525 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA+ CG++S G L CP P+ P D + K+ +C +VCC E+Q
Sbjct: 23 HEKGRCAIRGQCGKQSFFGSELPCPDNGPATTPADDVRKKLVDICGAQWSDTDVCCDEDQ 82
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
L +A PI+ CPAC NF NLFC +CSP+QS FINVT V +D
Sbjct: 83 LDALKTNLDRATPIINACPACKENFYNLFCTFTCSPDQSTFINVTQTQPKGDKYLVTELD 142
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V + +G Y +CKDVKFG N +A+DF+G GA NY + FLG K F GSP+ I
Sbjct: 143 NLVADEYGSTFYDSCKDVKFGATNGKAMDFIGGGAKNYTLFLKFLGDK---KFLGSPFQI 199
Query: 206 DF-KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGS 264
+F + +D M+ M+ Y C+ ++G
Sbjct: 200 NFPRPNEVDFPGMDAMSKHAYPCDTDD---ERYRCACLDCGGSCTELPEVQEDKQCQVGL 256
Query: 265 LKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEV 324
L C+ ++ V+Y + +L + S E + + + S ++ +G++
Sbjct: 257 LP--CLSFAVIVVYSCFLALLCAAVAGHIAYQKHSRHKS-ERMRLLQDTSPSDDEDEGDI 313
Query: 325 LVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVET 384
+ ++ F+ W + G A P I + +S+ +V L+ G RF +ET
Sbjct: 314 VHNVGMMDRPTKHYFLNTWCDRMFSRLGYVCASFPAITIVTSILVVGLMSLGWFRFQIET 373
Query: 385 RPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFE 444
P LWV P+S AA+EK FFD PF+R EQ + ++ G P +++ + ++ F
Sbjct: 374 DPVNLWVSPDSAAAQEKAFFDEKFGPFFRAEQAFLVN--DTSEGSGP-VLSYETLDWWFG 430
Query: 445 IQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCF 504
++ ++ ++++ G V+L +C KP+G+DC QS+ YFQ D F N +
Sbjct: 431 VENQIQRLKSSQHG--VTLDKVCFKPVGDDCVVQSVTGYFQGD---FANVSPTSWKDDLL 485
Query: 505 QHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN 549
Q + +C F+ PL+P GG + + +A A ++T+ V N
Sbjct: 486 QCVDNPSSCLPTFQQPLDPHLLFGGVN-ESVLDAKALVVTWVVQN 529
>G9P5M7_HYPAI (tr|G9P5M7) Putative uncharacterized protein OS=Hypocrea
atroviridis (strain ATCC 20476 / IMI 206040)
GN=TRIATDRAFT_78561 PE=4 SV=1
Length = 1270
Score = 244 bits (624), Expect = 5e-62, Method: Compositional matrix adjust.
Identities = 161/546 (29%), Positives = 266/546 (48%), Gaps = 36/546 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA CG++S GK L C + P D L ++ LC + G VCC +Q
Sbjct: 28 HELGRCAFRGQCGKQSFFGKELPCVDNGLAEDPDDDLRKELVELCGSQWSEGPVCCNLDQ 87
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++A+ +G CPAC NF N+FC+ +CSP+QS FINVT +++ + V +D
Sbjct: 88 VKALKSEMGTPRTLIGSCPACKENFFNMFCKFTCSPDQSTFINVTDVAKKGNKLLVTELD 147
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E G GLY++CK+VKFG N+RA+D +G GA NY + FLG K P GSP I
Sbjct: 148 QLISEEHGSGLYNSCKEVKFGGANSRAMDLIGGGAKNYHDMLKFLGDKKP--LVGSPIQI 205
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
++ D M + CND ++G
Sbjct: 206 NYPEK-YDQPGMAPLQTKPKKCNDED---PAYRCVCVDCPEVCPKLPDVKEAGSCRVG-- 259
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
K+ C+ + Y VL+ LF + L+ E S ++ +G +
Sbjct: 260 KLPCLSFASIFTYGVLLLALFVAVFGHIFWAKYQKRRVERTRLLHES-SHSDDEDEGGPI 318
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ D R + ++ + +R G +AR P++ + SL +V +L G RF++E
Sbjct: 319 LTDAMRDQPTKRYWLNDRCDKAFRQLGNMSARFPSLTIGVSLVVVAILSAGWFRFDIEQD 378
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S+AA+EKE+FDS+ PF+R E++ + +++ P +++ + ++ EI
Sbjct: 379 PARLWVSPTSEAAQEKEYFDSNFGPFFRAEKIFLVN--DTKSSGPSPVLSYETLKWWAEI 436
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
++ V+ ++ + G +L D+C KP G+ C QS+ QY+ + GG++ +
Sbjct: 437 EKSVEALQGSMYG--STLDDVCFKPTGDACVIQSVTQYWY-------SKGGIDSKYWKDD 487
Query: 506 HYTSTET---CFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAI 562
+ ++ C AF P+EPT LGG+ ++ ++ A +T+ V+NA + D +AI
Sbjct: 488 LRSCAKSPVDCRPAFGQPIEPTMILGGYE-DDVVDSQAMTVTWVVSNA-AENSDTLLRAI 545
Query: 563 AWEKAF 568
WE A
Sbjct: 546 DWENAL 551
>M0RSW1_MUSAM (tr|M0RSW1) Uncharacterized protein OS=Musa acuminata subsp.
malaccensis PE=4 SV=1
Length = 911
Score = 244 bits (623), Expect = 7e-62, Method: Compositional matrix adjust.
Identities = 107/168 (63%), Positives = 139/168 (82%)
Query: 406 SHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSD 465
SH+ + QLI+A + S+ +PP+I+TD N++LLFE+Q+KVD++RANYSG +VSL+D
Sbjct: 35 SHVTRVISLLQLILAGISGSDAERPPNIITDKNLKLLFELQKKVDDLRANYSGSMVSLAD 94
Query: 466 ICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTT 525
ICLKPLG+DCATQS+LQYF+MDP N+D YGG++H +YCFQH++S E C SAF APL+P+T
Sbjct: 95 ICLKPLGKDCATQSVLQYFKMDPQNYDAYGGLDHVQYCFQHFSSAENCLSAFHAPLDPST 154
Query: 526 ALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
ALGGFSGNNYSEASAF+ITYPVNN L + E A+AWEKAFI+L +
Sbjct: 155 ALGGFSGNNYSEASAFVITYPVNNQLDETSTEYRSAVAWEKAFIRLIQ 202
>E9CWG5_COCPS (tr|E9CWG5) Patched sphingolipid transporter OS=Coccidioides
posadasii (strain RMSCC 757 / Silveira) GN=CPSG_01798
PE=4 SV=1
Length = 1271
Score = 244 bits (623), Expect = 8e-62, Method: Compositional matrix adjust.
Identities = 171/564 (30%), Positives = 265/564 (46%), Gaps = 43/564 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ +H CA+ CG++S G L CP + +P + + K+ SLC G
Sbjct: 23 AQGHTDLHEEGRCAIRGNCGKKSFFGGELPCPNNGLAREPEEKVRDKLVSLCGDKWKHGP 82
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLFINVT +V G
Sbjct: 83 VCCEDEQIDALSKNLNLAQGIIASCPACKENFFNIFCTFTCSPDQSLFINVTQTEEVRGK 142
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
+ V +D +E + G Y +CKDVK G +A+DF+G GA NY ++ FLG K
Sbjct: 143 LLVTELDNLWSEKYQSGFYDSCKDVKNGASGGKAMDFIGGGAKNYVQFLKFLGDK---KL 199
Query: 199 PGSPYSIDFKTTILD--SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
GSP+ I+F T + M + +CND+
Sbjct: 200 LGSPFQINFITEPRNPMHDGMRALPEIPKACNDSD---GAFRCSCVDCPAVCPQLPALAT 256
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+G L C ++ V+Y V + +L I E + + + S +
Sbjct: 257 ETYCHVGYLP--CFSFAVIVIYSVGLVLLVSGILARIAFRKHRE-RKIERVRLLQDASPS 313
Query: 317 NLPKDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
+ +G+++ + P R V + L + GR+ R PT+ + +S IV
Sbjct: 314 DEEDEGDIIENAGSLTRPTRNYRVNAT-----LDKVFSRLGRFCTRFPTLTIVTSFLIVG 368
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
L+ G LRF+VE P +LWV P S+AA EK++FDS+ PFYR EQ + + P
Sbjct: 369 LMSLGWLRFSVEKDPVRLWVSPTSEAAREKQYFDSNFGPFYRAEQAFLV------NDGPG 422
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
S+++ + + F+++ +V + + +GL SL D+C P G C QS+ YF N
Sbjct: 423 SVLSYETLSWWFDVESRVRRMISLNNGL--SLEDVCFNPTGNACVVQSVTGYFGGSFANV 480
Query: 492 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNNA 550
D + ++C + S + C F+ PL P LGG+ + +A A I+T+ VNN
Sbjct: 481 DPNNWQKQLKHCTESPGSRD-CLPDFQQPLSPNMILGGYDDTGDVLDAKALIVTWVVNNH 539
Query: 551 LTKVGDENGKAIAWEKAFIQLAKV 574
+E AI WE + ++ +V
Sbjct: 540 EQGTKEE-ANAIDWEDSVKRVLQV 562
>C5PGL6_COCP7 (tr|C5PGL6) Patched family protein OS=Coccidioides posadasii
(strain C735) GN=CPC735_050390 PE=4 SV=1
Length = 1271
Score = 244 bits (623), Expect = 8e-62, Method: Compositional matrix adjust.
Identities = 171/564 (30%), Positives = 265/564 (46%), Gaps = 43/564 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ +H CA+ CG++S G L CP + +P + + K+ SLC G
Sbjct: 23 AQGHTDLHEEGRCAIRGNCGKKSFFGGELPCPNNGLAREPEEKVRDKLVSLCGDKWKHGP 82
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLFINVT +V G
Sbjct: 83 VCCEDEQIDALSKNLNLAQGIIASCPACKENFFNIFCTFTCSPDQSLFINVTQTEEVRGK 142
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
+ V +D +E + G Y +CKDVK G +A+DF+G GA NY ++ FLG K
Sbjct: 143 LLVTELDNLWSEKYQSGFYDSCKDVKNGASGGKAMDFIGGGAKNYVQFLKFLGDK---KL 199
Query: 199 PGSPYSIDFKTTILD--SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
GSP+ I+F T + M + +CND+
Sbjct: 200 LGSPFQINFITEPRNPMHDGMRALPEIPKACNDSD---GAFRCSCVDCPAVCPQLPALAT 256
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+G L C ++ V+Y V + +L I E + + + S +
Sbjct: 257 ETYCHVGYLP--CFSFAVIVIYSVGLVLLVSGILARIAFRKHRE-RKIERVRLLQDASPS 313
Query: 317 NLPKDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
+ +G+++ + P R V + L + GR+ R PT+ + +S IV
Sbjct: 314 DEEDEGDIIENAGSLTRPTRNYRVNAT-----LDKVFSRLGRFCTRFPTLTIVTSFLIVG 368
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
L+ G LRF+VE P +LWV P S+AA EK++FDS+ PFYR EQ + + P
Sbjct: 369 LMSLGWLRFSVEKDPVRLWVSPTSEAAREKQYFDSNFGPFYRAEQAFLV------NDGPG 422
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
S+++ + + F+++ +V + + +GL SL D+C P G C QS+ YF N
Sbjct: 423 SVLSYETLSWWFDVESRVRRMISLNNGL--SLEDVCFNPTGNACVVQSVTGYFGGSFANV 480
Query: 492 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNNA 550
D + ++C + S + C F+ PL P LGG+ + +A A I+T+ VNN
Sbjct: 481 DPNNWQKQLKHCTESPGSRD-CLPDFQQPLSPNMILGGYDDTGDVLDAKALIVTWVVNNH 539
Query: 551 LTKVGDENGKAIAWEKAFIQLAKV 574
+E AI WE + ++ +V
Sbjct: 540 EQGTKEE-ANAIDWEDSVKRVLQV 562
>C1G8F9_PARBD (tr|C1G8F9) Niemann-Pick C1 protein OS=Paracoccidioides
brasiliensis (strain Pb18) GN=PADG_03545 PE=4 SV=1
Length = 1235
Score = 244 bits (622), Expect = 8e-62, Method: Compositional matrix adjust.
Identities = 181/558 (32%), Positives = 260/558 (46%), Gaps = 36/558 (6%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ IH CAM CG+ S G L CP + P K+ SLC TGN
Sbjct: 22 AQGETKIHEEGRCAMRGHCGKLSFFGGQLPCPDNGLAKAPTADTRKKLVSLCGDKWKTGN 81
Query: 87 VCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDL 146
VCC + Q+ A I+ CPAC NF NLFC +CSP+QSLFINVT V V +D
Sbjct: 82 VCCEDPQI-AEGIIASCPACKENFFNLFCSFTCSPDQSLFINVTQTDTVKDKKVVTELDN 140
Query: 147 YVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSID 206
+E + G Y +CKDVK G RA+DF+G GA N+ ++ FLG K GSP+ I+
Sbjct: 141 LWSEVYQVGFYDSCKDVKNGASGGRAMDFIGGGARNFTQFLKFLGDK---KLLGSPFQIN 197
Query: 207 FKTTILDSSPMEL----MNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
F T PM+ + + SC+D +
Sbjct: 198 FMTQ--PKGPMDAGMRPLPTTPKSCSDADQKYRCSCIDCPAVCPQLPALPEESYCHVRHL 255
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
C+ S+ ++Y V + ++ + E + + S ++ +G
Sbjct: 256 -----PCLSFSVIIVYSVFLLLMVA-VTLVHVVFRKRQQRKLERARLLQDTSPSDDEDEG 309
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA---ARRPTIVLCSSLAIVILLCFGLLR 379
+ L+ D + Q S+ + S F A+ R AR P + + +S+ I LL G LR
Sbjct: 310 D-LIDDAGLLDRPQVSY--KLNSVFDAAFSRLGGVCARFPALTITTSIIICGLLSLGWLR 366
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ--LIIATLPESEHGKPPSIVTDD 437
F VE P KLWV P S AA+EK FFD + PFYR EQ LI T P+ P +++ +
Sbjct: 367 FTVERDPVKLWVSPTSAAAQEKAFFDENFGPFYRAEQAFLINDTHPDG----PGPVLSYE 422
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
+ F+++ +V + + GL +L D+C KP G C QS+ YF N D
Sbjct: 423 TLSWWFDVENRVRRMISLEKGL--ALEDVCFKPTGRACVVQSLTGYFGGSFSNVDPNNWK 480
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKVGD 556
H +YC Q S E C F+ PL+P LGG+ N +A+A ++T+ VNN +
Sbjct: 481 SHLKYCAQSPGSIE-CLPDFQQPLKPEMILGGYGQTKNVLDATALVVTWVVNNHAPGSEN 539
Query: 557 ENGKAIAWEKAFIQLAKV 574
E G A+ WE + ++ +V
Sbjct: 540 EAG-AVDWEDSLKRVLEV 556
>F2PP73_TRIEC (tr|F2PP73) Vacuolar membrane protein OS=Trichophyton equinum
(strain ATCC MYA-4606 / CBS 127.97) GN=TEQG_02723 PE=4
SV=1
Length = 1249
Score = 244 bits (622), Expect = 9e-62, Method: Compositional matrix adjust.
Identities = 176/565 (31%), Positives = 266/565 (47%), Gaps = 37/565 (6%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI- 83
SL+ A ++ +H CA+ CG++S G L CP + +P + ++ LC
Sbjct: 17 SLSQAALTE-VHEAGRCAIRGNCGRQSFFGGELPCPDNGLAHQPEQRVRQQLVELCGKKW 75
Query: 84 -TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
G VCC EEQ+ A+ I+ CPAC NF NLFC +CSP+QSLFINVT +++
Sbjct: 76 EDGPVCCKEEQINALSTNLKLAGGIISSCPACKENFFNLFCTFTCSPDQSLFINVTDVAE 135
Query: 135 VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKV 194
V+G + V +D +E + LY +CK+VK G +A+DF+G GA NY ++ FLG K
Sbjct: 136 VNGKLLVTELDNVWSEEYQSNLYDSCKNVKNGASGGKAMDFIGGGAKNYTQFLKFLGDK- 194
Query: 195 PPGFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
GSP+ I+F T D M+ + SC D +
Sbjct: 195 --KLLGSPFQINFLTEPRRPKDGQGMKPVPDETRSCADKN---EAYRCSCIDCPSVCAEL 249
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
K+GSL C+ + ++Y I L+ ++ I LL
Sbjct: 250 PAIKGEKPCKVGSLP--CLTFAAILVYSISLMLIVVLAIARSAFKRHRSRNIERVRLLQD 307
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
+ P D E + Q + L N + G AR P + + ++ I
Sbjct: 308 DA------PSDEEEEAEVIEETRIPQPYMLNHVLGNAFNRLGGICARFPALTITLTVIIS 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+LL G LRF VET P +LWV P S AAEEK +FDS+ PFYRIEQ+ + + + + KP
Sbjct: 362 LLLSLGWLRFAVETDPVRLWVSPNSAAAEEKHYFDSNFEPFYRIEQVFV--VKDVDADKP 419
Query: 431 PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
++ + + F+++ +V + + L +L D+C P G C QS+ YF N
Sbjct: 420 EPVLDYETLGWWFDVENRVRRMISLNRRL--TLDDVCFNPTGRACVVQSVSGYFGGSFAN 477
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNN 549
+ H E+C Q S + C F+ PL P LGGF+ + +A + IIT+ VNN
Sbjct: 478 VNPNTWRTHLEHCAQSPGSRD-CLPDFQQPLAPEMVLGGFNDTADILDARSLIITWVVNN 536
Query: 550 ALTKVGDENGKAIAWEKAFIQLAKV 574
+ D +A+ WE+ Q+ +V
Sbjct: 537 -YEQGSDMEARAMDWEETLKQVLQV 560
>C0S090_PARBP (tr|C0S090) Niemann-Pick C1 protein OS=Paracoccidioides
brasiliensis (strain Pb03) GN=PABG_01848 PE=4 SV=1
Length = 1235
Score = 243 bits (621), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 181/558 (32%), Positives = 259/558 (46%), Gaps = 36/558 (6%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ IH CAM CG+ S G L CP + P K+ SLC TGN
Sbjct: 22 AQGETKIHEEGRCAMRGHCGKLSFFGGQLPCPDNGLAKAPTADTRKKLVSLCGDKWKTGN 81
Query: 87 VCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDL 146
VCC + Q+ A I+ CPAC NF NLFC +CSP+QSLFINVT V V +D
Sbjct: 82 VCCEDPQI-AEGIIASCPACKENFFNLFCSFTCSPDQSLFINVTQTDTVKDKKVVTELDN 140
Query: 147 YVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSID 206
+E + G Y +CKDVK G RA+DF+G GA N+ ++ FLG K GSP+ I+
Sbjct: 141 LWSEVYQVGFYDSCKDVKNGASGGRAMDFIGGGARNFSQFLKFLGDK---KLLGSPFQIN 197
Query: 207 FKTTILDSSPMEL----MNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
F T PM+ + + SC+D +
Sbjct: 198 FMTQ--PKGPMDAGMRPLPTTPKSCSDADQKYRCSCIDCPAVCPQLPALPEESYCHVRHL 255
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
C+ S+ + Y V + ++ + E + + S ++ +G
Sbjct: 256 -----PCLSFSVIIFYSVFLLLMVA-VTLVHVVFRKRQQRKLERARLLQDTSPSDDEDEG 309
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA---ARRPTIVLCSSLAIVILLCFGLLR 379
+ L+ D + Q S+ + S F A+ R AR P + + +S+ I LL G LR
Sbjct: 310 D-LIDDAGLLDRPQVSY--KLNSVFDAAFSRLGGVCARFPALTITTSIIICGLLSLGWLR 366
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ--LIIATLPESEHGKPPSIVTDD 437
F VE P KLWV P S AA+EK FFD + PFYR EQ LI T P+ P +++ +
Sbjct: 367 FTVERDPVKLWVSPTSAAAQEKAFFDENFGPFYRAEQAFLINDTHPDG----PGPVLSYE 422
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
+ F+++ +V + + GL +L D+C KP G C QS+ YF N D
Sbjct: 423 TLSWWFDVENRVRRMISLEKGL--ALEDVCFKPTGRACVVQSLTGYFGGSFSNVDPNNWK 480
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKVGD 556
H +YC Q S E C F+ PL+P LGG+ N +A+A ++T+ VNN +
Sbjct: 481 SHLKYCAQSPGSIE-CLPDFQQPLKPEMILGGYGQTKNVLDATALVVTWVVNNHAPGSEN 539
Query: 557 ENGKAIAWEKAFIQLAKV 574
E G A+ WE + ++ +V
Sbjct: 540 EAG-AVDWEDSLKRVLEV 556
>J3KJB8_COCIM (tr|J3KJB8) Niemann-Pick C type protein family OS=Coccidioides
immitis (strain RS) GN=CIMG_01384 PE=4 SV=1
Length = 1271
Score = 243 bits (621), Expect = 1e-61, Method: Compositional matrix adjust.
Identities = 171/564 (30%), Positives = 264/564 (46%), Gaps = 43/564 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ +H CA+ CG++S G L CP + +P + + K+ SLC G
Sbjct: 23 AQGHTDLHEEGRCAIRGNCGKKSFFGGELPCPDNGLAREPEEKVRDKLVSLCGDKWKHGP 82
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLFINVT +V G
Sbjct: 83 VCCEDEQIDALSKNLNLAQGIIASCPACKENFFNIFCTFTCSPDQSLFINVTQTEEVRGK 142
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
+ V +D +E + G Y +CKDVK G +A+DF+G GA NY + FLG K
Sbjct: 143 LLVTELDNLWSEKYQSGFYDSCKDVKNGASGGKAMDFIGGGAKNYVHFLKFLGDK---KL 199
Query: 199 PGSPYSIDFKTTILD--SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
GSP+ I+F T + M + +CND+
Sbjct: 200 LGSPFQINFITEPRNPMHDGMRALPEIPKACNDSD---GAFRCSCVDCPAVCPQLPALAT 256
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+G L C ++ V+Y V + +L I E + + + S +
Sbjct: 257 ETYCHVGYLP--CFSFAVIVIYSVGLVLLVSGILARIAFRKHRE-RKIERVRLLQDASPS 313
Query: 317 NLPKDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
+ +G+++ + P R V + L + GR+ AR P + + +S IV
Sbjct: 314 DEEDEGDIIENAGSLTRPTRNYRVNAT-----LDKVFSRLGRFCARFPALTIVTSFLIVG 368
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
L+ G LRF+VE P +LWV P S+AA EK++FDS+ PFYR EQ + + P
Sbjct: 369 LMSLGWLRFSVEKDPVRLWVSPTSEAAREKQYFDSNFGPFYRAEQAFLV------NDGPG 422
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
S+++ + + F+++ +V + + +GL SL D+C P G C QS+ YF N
Sbjct: 423 SVLSYETLSWWFDVENRVRRMISLNNGL--SLEDVCFNPTGNACVVQSVTGYFGGSFANV 480
Query: 492 DNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNNA 550
D + ++C + S + C F+ PL P LGG+ + +A A I+T+ VNN
Sbjct: 481 DPNNWQKQLKHCTESPGSRD-CLPDFQQPLSPNMILGGYDDTGDVLDAKALIVTWVVNNH 539
Query: 551 LTKVGDENGKAIAWEKAFIQLAKV 574
+ E AI WE + ++ +V
Sbjct: 540 -EQGTKEEANAIDWEDSIKRVLQV 562
>E3S9W3_PYRTT (tr|E3S9W3) Putative uncharacterized protein OS=Pyrenophora teres
f. teres (strain 0-1) GN=PTT_19857 PE=4 SV=1
Length = 1276
Score = 243 bits (620), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 160/553 (28%), Positives = 256/553 (46%), Gaps = 36/553 (6%)
Query: 9 ISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVK 67
+++G + + + P LT H CA+ CG++S G L CP +
Sbjct: 12 MTLGLVSMLATAALAGPHLTTK------HEKGRCAIRGQCGKQSFFGSELPCPDNGLATT 65
Query: 68 PHDLLSAKIQSLCPT--ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCEL 117
P D + K+ +C +VCC E+QL +A PI+ CPAC NF NLFC
Sbjct: 66 PADDVRKKLVDICGAQWSDTDVCCDEDQLDALKTNLDRATPIINACPACKENFYNLFCTF 125
Query: 118 SCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVG 177
+CSP+QS FINVT V +D V + + Y +CKDVKFG N +A+DF+G
Sbjct: 126 TCSPDQSTFINVTQTQPKGDKYLVTELDNLVADEYASTFYDSCKDVKFGATNGKAMDFIG 185
Query: 178 AGANNYKEWFAFLGQKVPPGFPGSPYSIDF-KTTILDSSPMELMNASVYSCNDTSLGXXX 236
GA NY + FLG K F GSP+ I+F + +D M+ M+ Y C+
Sbjct: 186 GGAKNYTLFLKFLGDK---KFLGSPFQINFPRPNEVDFPGMDAMSKHAYPCDTDD---ER 239
Query: 237 XXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXX 296
++G L C+ ++ V+Y + +L +
Sbjct: 240 YRCACLDCGGSCTELPEVQEDKQCQVGLLP--CLSFAVIVVYSCFLALLCAAVAGHIAYQ 297
Query: 297 XXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAA 356
S E + + + S ++ +G+++ ++ F+ W + G A
Sbjct: 298 KHSRHKS-ERMRLLQDTSPSDDEDEGDIVHNVGMMDRPTKHYFVNTWCDRMFSRLGYVCA 356
Query: 357 RRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ 416
P I + +S+ +V L+ G LRF VET P LWV P+S AA+EK FFD PF+R EQ
Sbjct: 357 SFPAITIATSILVVALMSLGWLRFQVETDPVNLWVSPDSAAAQEKTFFDERFGPFFRAEQ 416
Query: 417 LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCA 476
+ ++ G P +++ + ++ F ++ ++ ++++ G V+L +C KP+G+DC
Sbjct: 417 AFLVN--DTSEGSGP-VLSYETLDWWFGVENQIQRLKSSEHG--VTLDKVCFKPVGDDCV 471
Query: 477 TQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYS 536
QSI YFQ D F N + Q + +C F+ PL+P GG + +
Sbjct: 472 VQSITGYFQSD---FANVSPTSWQDDLLQCVDNPSSCLPTFQQPLDPHLLFGGVN-ESVL 527
Query: 537 EASAFIITYPVNN 549
+A A ++T+ V N
Sbjct: 528 DAKALVVTWVVQN 540
>D4AM06_ARTBC (tr|D4AM06) Putative uncharacterized protein OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371)
GN=ARB_05354 PE=4 SV=1
Length = 1271
Score = 243 bits (620), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 176/565 (31%), Positives = 266/565 (47%), Gaps = 37/565 (6%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI- 83
SL+ A ++ IH CA+ CG++S G L CP + +P + ++ LC
Sbjct: 17 SLSQAALTE-IHEAGRCAIRGNCGKQSFFGGELPCPDNGLAHQPDQRVRQQLVELCGKKW 75
Query: 84 -TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
G VCC EEQ+ A+ ++ CPAC NF NLFC +CSP+QSLFINVT+ ++
Sbjct: 76 EDGPVCCKEEQINALSTNLKLAGGVISSCPACKENFFNLFCTFTCSPDQSLFINVTNAAE 135
Query: 135 VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKV 194
V+G + V +D +E + Y +CK+VK G +A+DF+G GA NY ++ FLG K
Sbjct: 136 VNGKLLVTELDNVWSEEYQSNFYDSCKNVKNGASGGKAMDFIGGGAKNYMQFLKFLGDK- 194
Query: 195 PPGFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
GSP+ I+F T D M+ ++ SC D +
Sbjct: 195 --KLLGSPFQINFLTEPRRPKDGQGMKPVSDETRSCADKN---EAYRCSCIDCPSVCAEL 249
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
K+GSL C+ + ++Y I L+ ++ I LL
Sbjct: 250 PAIKGEKPCKVGSLP--CLTFAAILVYSISLMLIVVLAIARSAFKRHRSRNIQRVRLLQD 307
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
+ P D E + Q + L N + G AR P + + ++ I
Sbjct: 308 DA------PSDEEEEAEVIEDTRIPQPYMLNHVLGNAFNRLGGICARFPALTITLTVIIS 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+LL G LRF VET P +LWV P S AAEEK +FDS+ PFYRIEQ+ + + + E KP
Sbjct: 362 LLLSLGWLRFAVETDPVRLWVSPNSAAAEEKHYFDSNFEPFYRIEQVFV--VKDVEADKP 419
Query: 431 PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
++ + + F+++ +V + + L +L D+C P G C QS+ YF N
Sbjct: 420 EPVLDYETLGWWFDVENRVRRMISLNRRL--TLDDVCFNPTGRGCVVQSVSGYFGGSFAN 477
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNN 549
+ H E+C Q S + C F+ PL P LGGF+ + +A + IIT+ VNN
Sbjct: 478 VNPNTWRSHLEHCAQSPGSRD-CLPDFQQPLAPEMVLGGFNDTADILDARSLIITWVVNN 536
Query: 550 ALTKVGDENGKAIAWEKAFIQLAKV 574
+ D +A+ WE+ Q+ +V
Sbjct: 537 -YEQGSDMEARAMDWEETLKQVLQV 560
>F0UU14_AJEC8 (tr|F0UU14) Vacuolar membrane protein OS=Ajellomyces capsulata
(strain H88) GN=HCEG_08606 PE=4 SV=1
Length = 1251
Score = 243 bits (619), Expect = 2e-61, Method: Compositional matrix adjust.
Identities = 175/563 (31%), Positives = 258/563 (45%), Gaps = 60/563 (10%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ IH CA+ CG++S G L C + KP AK+ SLC TGN
Sbjct: 22 AQGETKIHEEGRCAIRGHCGKKSFFGGQLPCVDNGFAKKPAADTRAKLVSLCGDKWKTGN 81
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC ++Q+ A+ I+ CPAC NF NLFC +CSPNQSLFINVT +++G
Sbjct: 82 VCCDDDQIAALSSNLKLAAGIIASCPACKENFFNLFCSFTCSPNQSLFINVTQTDKINGR 141
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
V +D + + G Y +CKDVK G +A+DF+G GA NY + FLG K
Sbjct: 142 TAVTELDNLWSGGYQAGFYDSCKDVKNGATGGKAMDFIGGGAKNYSLFLKFLGDK---KL 198
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
GSP+ I+F T P EL +A++Y
Sbjct: 199 LGSPFQINFVTG--SKGPRELGDATLYQ-------------------------------R 225
Query: 259 XIKMGSLKVRCVDL--SLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
K ++ R + + S A L++ +++ +F + + L
Sbjct: 226 FQKRAVIRTRNIGVHASTAPLFVPIIYAVFLLLLVAGALGHFAFRRRQQRKLERVRLLQD 285
Query: 317 NLPKDGE---VLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
P D E L+ D + Q S+ + + G AR P + + +S+ + L
Sbjct: 286 TSPSDDEDEGDLIDDAGILDRPQTSYRLNSIFDAMFNRLGGACARFPALTITTSIILCGL 345
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
L G LRF VE P KLWV P+S AA EK FFD + PF+R EQ + ++ P
Sbjct: 346 LSLGWLRFAVEIDPVKLWVSPDSAAAREKAFFDENFGPFFRAEQAFLVN--DTHPSGPGP 403
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
+++ + + F+++ +V + + GL SL DIC P G+ C QS+ YF N D
Sbjct: 404 VLSYETLSWWFDVESRVRRMISLDKGL--SLDDICFNPTGKACVVQSLTGYFGGSFANVD 461
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNAL 551
H ++C + S E C F+ PL+P LGG+ +N A+A ++T+ VNN
Sbjct: 462 PNTWETHLKHCTESPGSVE-CLPDFQQPLKPEMILGGYGQTDNVLNATALVVTWVVNNHA 520
Query: 552 TKVGDENGKAIAWEKAFIQLAKV 574
E G AI WE + ++ +V
Sbjct: 521 PGTIAEAG-AIDWEGSLKRVLEV 542
>F2S6K3_TRIT1 (tr|F2S6K3) Patched sphingolipid transporter OS=Trichophyton
tonsurans (strain CBS 112818) GN=TESG_06641 PE=4 SV=1
Length = 1270
Score = 242 bits (618), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 175/565 (30%), Positives = 265/565 (46%), Gaps = 37/565 (6%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI- 83
SL+ A ++ +H CA+ CG++S G L CP + +P + ++ LC
Sbjct: 17 SLSQAALTE-VHEAGRCAIRGNCGRQSFFGGELPCPDNGLAHQPEQRVRQQLVELCGKKW 75
Query: 84 -TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
G VCC EEQ+ A+ I+ CPAC NF NLFC +CSP+QSLFINVT +++
Sbjct: 76 EDGPVCCKEEQINALSTNLKLAGGIISSCPACKENFFNLFCTFTCSPDQSLFINVTDVAE 135
Query: 135 VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKV 194
V+G + V +D +E + Y +CK+VK G +A+DF+G GA NY ++ FLG K
Sbjct: 136 VNGKLLVTELDNVWSEEYQSNFYDSCKNVKNGASGGKAMDFIGGGAKNYTQFLKFLGDK- 194
Query: 195 PPGFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
GSP+ I+F T D M+ + SC D +
Sbjct: 195 --KLLGSPFQINFLTEPRRPKDGQGMKPVPDETRSCADKN---EAYRCSCIDCPSVCAEL 249
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
K+GSL C+ + ++Y I L+ ++ I LL
Sbjct: 250 PAIKGEKPCKVGSLP--CLTFAAILVYSISLMLIVVLAIARSAFKRHRSRNIERVRLLQD 307
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
+ P D E + Q + L N + G AR P + + ++ I
Sbjct: 308 DA------PSDEEEEAEVIEETRIPQPYMLNHVLGNAFNRLGGICARFPALTITLTVIIS 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+LL G LRF VET P +LWV P S AAEEK +FDS+ PFYRIEQ+ + + + + KP
Sbjct: 362 LLLSLGWLRFAVETDPVRLWVSPNSAAAEEKHYFDSNFEPFYRIEQVFV--VKDVDADKP 419
Query: 431 PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
++ + + F+++ +V + + L +L D+C P G C QS+ YF N
Sbjct: 420 EPVLDYETLGWWFDVENRVRRMISLNRRL--TLDDVCFNPTGRACVVQSVSGYFGGSFAN 477
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNN 549
+ H E+C Q S + C F+ PL P LGGF+ + +A + IIT+ VNN
Sbjct: 478 VNPNTWRTHLEHCAQSPGSRD-CLPDFQQPLAPEMVLGGFNDTADILDARSLIITWVVNN 536
Query: 550 ALTKVGDENGKAIAWEKAFIQLAKV 574
+ D +A+ WE+ Q+ +V
Sbjct: 537 -YEQGSDMEARAMDWEETLKQVLQV 560
>C7Z5H5_NECH7 (tr|C7Z5H5) Predicted protein OS=Nectria haematococca (strain
77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=NhNCR1
PE=4 SV=1
Length = 1272
Score = 242 bits (618), Expect = 3e-61, Method: Compositional matrix adjust.
Identities = 165/543 (30%), Positives = 253/543 (46%), Gaps = 30/543 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P + L ++ LC TG VCC+ EQ
Sbjct: 29 HEAGRCAFRGHCGKQSLFGKELPCVDNDVAQDPEEELRNELVELCGEKWRTGPVCCSLEQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
+Q++ I+ CPAC NF NLFC +CSP+QSLFINVT ++ +G V +D
Sbjct: 89 VQSLKSELGTPATIVGSCPACKENFFNLFCTFTCSPDQSLFINVTDSAEKNGKHLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+E +G G Y +CK+VKFG N+RA+D +G GA NY + FLG K P F GSP+ I
Sbjct: 149 QLVSEEYGSGFYDSCKEVKFGGANSRAMDLIGGGAKNYTQMLKFLGDKKP--FVGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
++ T D M ++ CND +G L
Sbjct: 207 NYPTEYSDPE-MHPLDMKPKKCNDED---PAYRCVCVDCPEVCPELPAVKDSKSCHVGLL 262
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + +Y VL+F L I L+ E S ++ +G +
Sbjct: 263 P--CLSFASIFIYSVLLFALLASIFGHVAWKRYAQRQVERTRLLHES-SHSDDEDEGGPV 319
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R + ++ + + G AAR P + + SL +V +L GL RF++E
Sbjct: 320 QTEAMRDRPTKRYWVNDKCDKAFYQLGHAAARFPGLSIGLSLLVVAILSAGLFRFDLERE 379
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FDS+ PFYR E++ + ++ P +++ + ++ ++
Sbjct: 380 PARLWVSPSSAAAQEKAYFDSNFGPFYRAEKVFLVN--DTNPSGPGPVLSYETLKWWMDV 437
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
++ ++++ + G L D+C KP G C QS Y+ FD E C +
Sbjct: 438 EKSIEKLESPTYGKF--LKDLCYKPTGNACVVQSPTAYW-YSKGGFDQKHWEEDLRSCAK 494
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
+ C F P+EP GG+ ++ EA A +T+ VNNA D +A+ WE
Sbjct: 495 ---TPVDCRPEFGQPIEPNMIFGGYD-DDVLEAKAITVTWVVNNAQEGT-DALARAVDWE 549
Query: 566 KAF 568
A
Sbjct: 550 NAL 552
>R7Z255_9EURO (tr|R7Z255) Uncharacterized protein OS=Coniosporium apollinis CBS
100218 GN=W97_07317 PE=4 SV=1
Length = 1292
Score = 242 bits (617), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 165/563 (29%), Positives = 263/563 (46%), Gaps = 44/563 (7%)
Query: 25 PSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI 83
PSLT H CA+ CG+ G L CP + +P + K+ +C +
Sbjct: 44 PSLTQK------HEAGRCAIRGHCGKVGFFGSDLPCPDNGLAEEPEKNVRKKLVEICGSK 97
Query: 84 --TGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS 133
G +CC EEQL +A ++ CPAC NF NLFC +CSP+QSLF+NVT+ +
Sbjct: 98 WDDGKICCKEEQLDSLKTNLKRAESLIAACPACKENFFNLFCTFTCSPDQSLFVNVTNTT 157
Query: 134 QVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQK 193
V +D +++ +G G Y +CKDVKFG N+RA+D +G GA NY ++F FLG K
Sbjct: 158 PKGDKFLVTELDTLISDAYGSGFYDSCKDVKFGATNSRAMDLIGGGAKNYTQFFKFLGDK 217
Query: 194 VPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
P GSP+ ++F + P M+ MN Y CN T
Sbjct: 218 KP---FGSPFQLNFPRPSGAAFPDMKAMNDKAYPCNSTD---EKYRCACVDCASSCPELP 271
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXX-XXXXXXXXGSSAEPLLVSE 311
+G L LS AV+ + +F+ F I E L + +
Sbjct: 272 KVTETKQCMVGLLPC----LSFAVILVYSIFIAFLVIAVSGHVAYAKHEKHKNERLRLLQ 327
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
++ +G+++ ++ ++ + G + A P I + S+ +V
Sbjct: 328 DIEPSDDEDEGDIVHNAGMLDRPTKHYYLNTLCDKAFSKLGYFCASFPAITISISVIVVG 387
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
LL G +RF VET P +LWV P+S AAEEK FFD + PF+R EQ+ + ++ P
Sbjct: 388 LLSLGWIRFAVETDPVRLWVAPDSAAAEEKAFFDKNFGPFFRAEQVFLVN--DTSPSGPG 445
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNF 491
+++ D + F+++ +V +++ G V+ +C KP G+ C QS+ YFQ D
Sbjct: 446 PVLSYDTLGWWFDVENRVQRLKSMKQG--VTFDKVCYKPTGDACVVQSVTGYFQGD---- 499
Query: 492 DNYGGVEHAEYCFQHYTSTET---CFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVN 548
+ V+ + Q ++ C AF+ PL+P GG++ + ++ A I+T+ V+
Sbjct: 500 --FSAVKPERWEQQIANCADSPVDCLPAFQQPLDPKMLFGGWN-KSVLDSEALIVTWVVS 556
Query: 549 NALTKVGDENGKAIAWEKAFIQL 571
N +E +A+ WE + L
Sbjct: 557 NHAEGT-EEIERAMDWEDSMKGL 578
>D4DB90_TRIVH (tr|D4DB90) Putative uncharacterized protein OS=Trichophyton
verrucosum (strain HKI 0517) GN=TRV_04389 PE=4 SV=1
Length = 1271
Score = 241 bits (616), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 175/567 (30%), Positives = 266/567 (46%), Gaps = 37/567 (6%)
Query: 24 SPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT 82
+ SL+ A ++ +H CA+ CG++S G L CP + +P + ++ LC
Sbjct: 15 TASLSQAALTE-VHEAGRCAIRGNCGKQSFFGGELPCPDNGLAHQPVQRVRQQLVELCGK 73
Query: 83 I--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
G VCC EEQ+ A+ ++ CPAC NF NLFC +CSP+QSLFINVT
Sbjct: 74 KWENGPVCCKEEQINALSTNLKLAGGVISSCPACKENFFNLFCTFTCSPDQSLFINVTDA 133
Query: 133 SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQ 192
++V+G + V +D +E + Y +CK+VK G +A+DF+G GA NY ++ FLG
Sbjct: 134 AEVNGKLLVTELDNVWSEEYQSNFYDSCKNVKNGASGGKAMDFIGGGAKNYVQFLKFLGD 193
Query: 193 KVPPGFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
K GSP+ I+F T D M+ ++ SC D +
Sbjct: 194 K---KLLGSPFQINFLTEPRRPKDGQGMKPVSDETRSCADKN---EAYRCSCIDCPSVCA 247
Query: 250 XXXXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLL 308
K+GSL C+ + ++Y I L+ ++ I LL
Sbjct: 248 ELPAIKGEKPCKVGSLP--CLTFAAILVYSISLMLIVVLAIARSAFKRHRSRNIQRVRLL 305
Query: 309 VSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
+ P D E + Q + L N + G AR P + + ++
Sbjct: 306 QDDA------PSDEEEEAEVIEDTRIPQPYMLNHVLGNAFNRLGGICARFPALTITLTVI 359
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG 428
I +LL G LRF VET P +LWV P S AAEEK +FDS+ PFYRIEQ+ + + + E
Sbjct: 360 ISLLLSLGWLRFAVETDPVRLWVSPNSAAAEEKHYFDSNFEPFYRIEQVFV--VKDVEAD 417
Query: 429 KPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDP 488
KP ++ + + F+++ +V + + L +L D+C P G C QS+ YF
Sbjct: 418 KPEPVLDYETLGWWFDVENRVRRMISLNRRL--TLDDVCFNPTGRGCVVQSVSGYFGGSF 475
Query: 489 DNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPV 547
N + H E+C Q S + C F+ PL P LGGF+ + +A + IIT+ V
Sbjct: 476 ANVNPNTWRSHLEHCAQSPGSRD-CLPDFQQPLAPEMVLGGFNDTADILDARSLIITWVV 534
Query: 548 NNALTKVGDENGKAIAWEKAFIQLAKV 574
NN + D +A+ WE+ Q+ +V
Sbjct: 535 NN-YEQGSDMEARAMDWEETLKQVLQV 560
>F2SLM3_TRIRC (tr|F2SLM3) Patched sphingolipid transporter OS=Trichophyton rubrum
(strain ATCC MYA-4607 / CBS 118892) GN=TERG_02938 PE=4
SV=1
Length = 1271
Score = 241 bits (616), Expect = 4e-61, Method: Compositional matrix adjust.
Identities = 173/565 (30%), Positives = 266/565 (47%), Gaps = 37/565 (6%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI- 83
SL+ A ++ +H CA+ CG++S G L CP + +P + ++ LC
Sbjct: 17 SLSQAALTE-VHEAGRCAIRGNCGKQSFFGGELPCPDNGLAHQPDQRVRQQLVHLCGKKW 75
Query: 84 -TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
G VCC EEQ+ A+ ++ CPAC NF NLFC +CSP+QSLFINVT +++
Sbjct: 76 EDGPVCCKEEQINALSTNLKLAGGVISSCPACKENFYNLFCTFTCSPDQSLFINVTDVAE 135
Query: 135 VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKV 194
V+G + V +D +E + Y +CK+VK G +A+DF+G GA NYK++ FLG K
Sbjct: 136 VNGKLLVTELDNVWSEEYQSNFYDSCKNVKNGASGGKAMDFIGGGAKNYKQFLKFLGDK- 194
Query: 195 PPGFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
GSP+ I+F T D M+ ++ SC D +
Sbjct: 195 --KLLGSPFQINFLTEPRRPKDGHGMKPVSDETRSCADKN---KAYRCSCIDCPSVCAEL 249
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
++GSL C+ + ++Y I L+ ++ I LL
Sbjct: 250 PAIKGQKPCRVGSLP--CLTFAAILVYSISLMLIVVLAIARSAFKRHRSRNIERVRLLQD 307
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
+ P D E + Q + L N + G AR P + + ++ I
Sbjct: 308 DA------PSDDEEEAEVIEDTGIPQPYMLNHILGNAFNRLGGICARFPALTITLTVIIS 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+LL G LRF VET P +LWV P S AAEEK +FDS+ PFYRIEQ+ + + + + KP
Sbjct: 362 LLLSLGWLRFAVETDPVRLWVSPNSAAAEEKHYFDSNFEPFYRIEQVFV--VKDVDTNKP 419
Query: 431 PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
++ + + F+++ +V + + L +L D+C P G C QS+ YF N
Sbjct: 420 EPVLDYETLGWWFDVENRVRRMISLNRRL--TLDDVCFNPTGRACVVQSVSGYFGGSFAN 477
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-NNYSEASAFIITYPVNN 549
+ H E+C Q S + C F+ PL P LGG + + +A + IIT+ VNN
Sbjct: 478 VNPNTWRSHLEHCAQSPGSRD-CLPDFQQPLAPEMVLGGLNDTTDILDARSLIITWVVNN 536
Query: 550 ALTKVGDENGKAIAWEKAFIQLAKV 574
+ D +A+ WE+ Q+ +V
Sbjct: 537 -YEQGSDMEARAMDWEETLKQVLQV 560
>M7TD76_9PEZI (tr|M7TD76) Putative patched sphingolipid transporter protein
OS=Eutypa lata UCREL1 GN=UCREL1_5138 PE=4 SV=1
Length = 1300
Score = 241 bits (615), Expect = 5e-61, Method: Compositional matrix adjust.
Identities = 169/548 (30%), Positives = 258/548 (47%), Gaps = 48/548 (8%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN--VCCTEEQ 93
H CAM CG + GK L C + P D L+ ++ +LC N VCC EQ
Sbjct: 29 HEAGRCAMRGHCGSKGFFGKQLPCVDNGLAPTPDDKLTEELVALCGPKWKNSDVCCNAEQ 88
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NL C +CSP+QSLF+NVT + +G V ID
Sbjct: 89 VESMKSALSTPNQIIGSCPACKDNFYNLICTFTCSPDQSLFLNVTDALEKNGKTLVSEID 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
VTE +G+G YS+C+DVKFG N+RA++F+G GA NY + F+G + P GSP+ I
Sbjct: 149 QLVTEEYGKGFYSSCEDVKFGASNSRAMNFIGGGATNYTQLLKFIGDEKP---IGSPFQI 205
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T+ D M + CND + GS
Sbjct: 206 NFPTSYSDPD-MAPRDMKPKKCNDED--------PNFRCACVDCPDVCPKLPDVTEAGSC 256
Query: 266 KVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
+V C+ + Y VL+F L G E L + +G ++ +G
Sbjct: 257 RVGVLPCLTFASIFTYSVLLFSL-GIALVAHVAWKKHTQRRNERLHLLQGAEPSDDEDEG 315
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNV 382
+++ R V++ I W + G + AR P I + SSL +VI+L G + F+V
Sbjct: 316 DLVRNPAMRDRPVKHYRINTWCDIAFSKLGHFCARFPMITIFSSLLVVIVLSVGWVNFDV 375
Query: 383 ETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELL 442
E P +LWV P S+AA++K FFD + PFYR E+ A L HG +++ + +
Sbjct: 376 EKNPARLWVSPTSEAAQDKAFFDENFGPFYRAEK---AFLVNDTHGP---VLSYETLTWW 429
Query: 443 FEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEY 502
++++ + +++ + G + D+C KP G C QS +F G ++ +
Sbjct: 430 AQVEKDIRQLKGDSFG--TNFDDVCFKPTGSACVVQSPTIFFD----------GTKNWKS 477
Query: 503 CFQHYTSTET-CFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDENGK 560
FQ T C F P++P +GG+ S N ++A A +T+ VNN L E
Sbjct: 478 SFQECAETPIFCRPDFGQPIDPNMIMGGYKSLENVTDAPAMTVTWVVNNHLDD-SPELAH 536
Query: 561 AIAWEKAF 568
A+ WEK+
Sbjct: 537 AMDWEKSL 544
>J3P1Z6_GAGT3 (tr|J3P1Z6) Niemann-Pick C1 protein OS=Gaeumannomyces graminis var.
tritici (strain R3-111a-1) GN=GGTG_07544 PE=4 SV=1
Length = 1287
Score = 241 bits (614), Expect = 7e-61, Method: Compositional matrix adjust.
Identities = 169/552 (30%), Positives = 255/552 (46%), Gaps = 46/552 (8%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG++S GK L C + +P ++ LC TGNVCC+ +Q
Sbjct: 36 HEAGRCAMRGHCGKKSWFGKELPCVDNGAATEPDADFRKELVELCGPKWQTGNVCCSSDQ 95
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
L+++ I+ CPAC NF NLFC +CSP+QSLFINVT + G + V +D
Sbjct: 96 LKSLKSELSTPRQIISSCPACKENFYNLFCTFTCSPDQSLFINVTRAEEKSGKLQVREVD 155
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V++T+G GLYS+CKDVKFG N++A+DF+G GA NY + FLG + GSP+ I
Sbjct: 156 QLVSQTYGSGLYSSCKDVKFGASNSKAMDFIGGGAKNYTQMLKFLGDEKA---IGSPFQI 212
Query: 206 DFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGS 264
+F + S P M + + CND ++G+
Sbjct: 213 NFPQSY--SQPGMSPRDMTPKRCNDDD---PDFRCACVDCPDVCPALPDVEDAGSCRVGA 267
Query: 265 LKVRCVDLSLAVLYIVLVF-----VLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLP 319
L C+ +Y VL+F + G + S+ +L
Sbjct: 268 LP--CLSFGAIFVYSVLLFASVAATVGGSFLKKHNERRRERLRLLQDTTASDDEDEGDLV 325
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
++ +L PQ+ + W + G AAR P I + SSL +V LL GL +
Sbjct: 326 QNNAML-DQPQKNYPL-----NSWCDTAFSKLGHTAARFPGITIISSLIVVALLSIGLFK 379
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA--TLPESEHGKPPSIVTDD 437
F++E P +LWV P S AA+EK FFD + PFYR ++ + TLP P +++ +
Sbjct: 380 FDIEKDPARLWVSPTSAAAQEKAFFDENFGPFYRANKVFLVNDTLPSG----PGPVLSHE 435
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
+ ++ + +++ G L D+C KP G C QS+ YF D D D
Sbjct: 436 TLTWWIGVENNIKQLKGPKFG--AQLQDVCFKPTGSACVVQSVAAYFGNDADLVDKETWQ 493
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-NNYSEASAFIITYPVNNALTKVGD 556
C + S +C F P+EP LGG+ N + A A +T+ +NN +
Sbjct: 494 GDLRNCAE---SPVSCRPDFGQPIEPGMILGGYGDVANVAAAPAMTVTWVLNN-FPEGSS 549
Query: 557 ENGKAIAWEKAF 568
E +A+ +E++
Sbjct: 550 EVSRAMDFEESL 561
>C0NRZ7_AJECG (tr|C0NRZ7) Putative uncharacterized protein OS=Ajellomyces
capsulata (strain G186AR / H82 / ATCC MYA-2454 / RMSCC
2432) GN=HCBG_05927 PE=4 SV=1
Length = 892
Score = 241 bits (614), Expect = 8e-61, Method: Compositional matrix adjust.
Identities = 175/560 (31%), Positives = 260/560 (46%), Gaps = 31/560 (5%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ IH CA+ CG++S G L C + KP AK+ SLC TGN
Sbjct: 22 AQGETKIHEEGRCAIRGHCGKKSFFGGQLPCVDNGFAKKPAADTRAKLVSLCGDKWKTGN 81
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC ++Q+ A+ I+ CPAC NF NLFC +CSPNQSLFINVT +++G
Sbjct: 82 VCCDDDQIAALSSNLKLAAGIIASCPACKENFFNLFCSFTCSPNQSLFINVTQTDKINGR 141
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
V +D +E + G Y +CKDVK G +A+DF+G GA NY + FLG K
Sbjct: 142 TAVTELDNLWSEGYQAGFYDSCKDVKNGATGGKAMDFIGGGAKNYSLFLKFLGDK---KL 198
Query: 199 PGSPYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
GSP+ I+F T M + +C+D+
Sbjct: 199 LGSPFQINFVTGSKGHEDLGMRPLPEIPKTCSDSD---EKYRCSCVDCPAVCPQLPALTE 255
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+G L C+ S+ V+Y V + +L E + + + S +
Sbjct: 256 ESYCHVGYLP--CLSFSVIVIYAVFLLLLVAGTLGHFAFRRRQQ-RKLERVRLLQDTSPS 312
Query: 317 NLPKDGEVLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+ +G+ L+ D + Q S+ + + G AR P + + +S+ + LL
Sbjct: 313 DDEDEGD-LIDDAGILDRPQTSYRLNSIFDAMFNRLGGACARFPALTITTSIILCGLLSL 371
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
G LRF VE P KLWV P+S AA EK FFD + PF+R EQ + ++ P +++
Sbjct: 372 GWLRFAVEIDPVKLWVSPDSAAAREKAFFDENFGPFFRAEQAFLVN--DTHPSGPGPVLS 429
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
+ + F+++ +V + + GL SL DIC P G+ C QS+ YF N D
Sbjct: 430 YETLSWWFDVESRVRRMISLDKGL--SLDDICFNPTGKACVVQSLTGYFGGSFANVDPNT 487
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKV 554
H ++C + S E C F+ PL+P LGG+ +N A+A ++T+ VNN
Sbjct: 488 WETHLKHCTESPGSVE-CLPDFQQPLKPEMILGGYGQTDNVLNATALVVTWVVNNHAPGT 546
Query: 555 GDENGKAIAWEKAFIQLAKV 574
E G AI WE + ++ +V
Sbjct: 547 IAEAG-AIDWEGSLKRVLEV 565
>B2APT9_PODAN (tr|B2APT9) Podospora anserina S mat+ genomic DNA chromosome 4,
supercontig 4 OS=Podospora anserina (strain S / ATCC
MYA-4624 / DSM 980 / FGSC 10383) PE=4 SV=1
Length = 1278
Score = 241 bits (614), Expect = 8e-61, Method: Compositional matrix adjust.
Identities = 180/589 (30%), Positives = 269/589 (45%), Gaps = 50/589 (8%)
Query: 1 MENMSTAIISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNC 59
M +S S G LL VL S ++ A + H CA+ CG +S G L C
Sbjct: 1 MTKLSQLFASGGLLLTVL-----STAVDAGYTPK--HEAGRCAIRGHCGSKSFFGSQLPC 53
Query: 60 PYPSPSVKPHDLLSAKIQSLC-PTIT-GNVCCTEEQLQAVP--------ILVGCPACLRN 109
+ +P D L ++ C P + G VCC EQ+ A+ I+ CPAC N
Sbjct: 54 LDNGLAEQPDDKLRKQLVDFCGPKWSEGPVCCDAEQVDALKSNLQTANQIISSCPACKDN 113
Query: 110 FLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMN 169
F N+FC +CSP+QSLFINVT + G V +D +++ +G G Y +CKDVKFG N
Sbjct: 114 FFNMFCTFTCSPDQSLFINVTKTMEKGGKTLVTELDQLISKEYGTGFYESCKDVKFGPTN 173
Query: 170 TRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCND 229
+RA+D +G GA NY + FLGQ+ GSP+ I+F + + M+ CND
Sbjct: 174 SRAMDLIGGGAKNYTQLLKFLGQE---RLGGSPFQINFPVDYPERN-MKPRPMVPKKCND 229
Query: 230 TSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWI 289
+G+L C+ + Y L+F+ +
Sbjct: 230 ED---PNFRCACIDCPAVCPELPDVEEAGSCYVGALP--CLSFASIFTYTALLFLAAVLV 284
Query: 290 XXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGE---VLVIDPQRQNEVQYSF-IQEWLS 345
S L+++ P D E L +P + Q ++ I W
Sbjct: 285 VGNVAWRKHAKRRSERLRLLTDA-----APSDDEDEGDLTQNPAMLDRPQKTYIINTWCD 339
Query: 346 NFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFD 405
+ G AAR P I + +S+ +V++L G L+F++E P +LWV P S AA+EK FFD
Sbjct: 340 AAFSRLGHAAARFPAITILTSVIVVMILSAGWLKFDIEQDPARLWVSPTSAAAQEKAFFD 399
Query: 406 SHLAPFYRIEQLIIA--TLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSL 463
+ PFYR E++ + T PE P +++ + + E++E V +++ S
Sbjct: 400 TQFGPFYRAEKVFLVNDTNPEG----PGPVLSYETLLWWMEVEESVRKLKG--PQFDSSF 453
Query: 464 SDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEP 523
++CLKP G C QS+ YFQ DPD G + C Q S C + PLEP
Sbjct: 454 QNLCLKPTGSACVVQSVAAYFQNDPDQVSPDGWKKTLRQCAQ---SPVECRPEYGQPLEP 510
Query: 524 TTALGGF--SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQ 570
+ LGG+ + +EA+A +T+ +NN D A+ WE+A Q
Sbjct: 511 SMILGGYPKGSEDPTEATAMTVTWVLNNHAEGSFDAE-LAMDWEEALKQ 558
>F7VMS2_SORMK (tr|F7VMS2) WGS project CABT00000000 data, contig 2.2 OS=Sordaria
macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) /
K-hell) GN=SMAC_00676 PE=4 SV=1
Length = 1280
Score = 240 bits (612), Expect = 1e-60, Method: Compositional matrix adjust.
Identities = 171/559 (30%), Positives = 256/559 (45%), Gaps = 52/559 (9%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
A I H CA+ CG +S G L C + +P D L ++ LC TG
Sbjct: 24 ADIYTPKHEAGRCAIRGHCGSKSLFGSQLPCVDNGLAEEPDDYLRQQLVDLCGPKWNTGP 83
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC EQ+ ++ I+ CPAC NF N+FC +CSP+QSLFINVT + +G
Sbjct: 84 VCCLAEQVDSLKSSLSTANQIISSCPACKDNFFNMFCTFTCSPDQSLFINVTKTLEKNGK 143
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGF 198
V +D ++E +G G YS+CKDVKFG N+RA+D +G GA NY + FLG + F
Sbjct: 144 TLVTELDQLISEEYGTGFYSSCKDVKFGPTNSRAMDLIGGGAKNYTQLLKFLGTE---RF 200
Query: 199 PGSPYSIDFKTTILD--SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
GSP+ I+F + + P+ + CND
Sbjct: 201 GGSPFQINFPVEYEEPGTKPLPMKPK---KCNDEDPNFRCACVDCPEVCPTLPEVE---- 253
Query: 257 XXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLV---- 309
K GS V C+ + + Y V++F + S L+
Sbjct: 254 ----KAGSCHVGALPCLSFASILTYSVILFTSIAAVVGHIAWKRHAKRRSERLRLLTDAA 309
Query: 310 -SEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
S+ +L ++G ++ PQ+ I W + + G AA P I + +S+
Sbjct: 310 PSDDEDEGDLTQNG-AMIDRPQKT-----YIINTWCDSAFSKLGYLAATFPAITIVTSIL 363
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG 428
I +L G F +E P +LWV P S AAEEK FFDSH FYR E++ + ++
Sbjct: 364 IASILSIGWFHFELEKNPARLWVSPTSPAAEEKAFFDSHFGAFYRAEKVFLVN--DTNPS 421
Query: 429 KPPSIVTDDNIELLFEIQEKVDEIR-ANYSGLLVSLSDICLKPLGEDCATQSILQYFQMD 487
P +++ D + ++++ + ++ ANY S D+CLKP G+ C QS+ YFQ D
Sbjct: 422 GPGPVLSRDTLLWWMDVEKSIAALKGANYGS---SFQDLCLKPTGDACVVQSVAAYFQDD 478
Query: 488 PDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYP 546
PD+ D C S C A+ PL+P+ LGG+ + +EASA +T+
Sbjct: 479 PDSVDPESWKSTLRTC---AASPVECRPAYGQPLDPSMILGGYPEDGDVAEASAMTVTWV 535
Query: 547 VNNALTKVGDENGKAIAWE 565
+ N + E +A+ WE
Sbjct: 536 LINP-PEDSPEVDRAMDWE 553
>C1GRY4_PARBA (tr|C1GRY4) Patched sphingolipid transporter (Ncr1)
OS=Paracoccidioides brasiliensis (strain ATCC MYA-826 /
Pb01) GN=PAAG_01279 PE=4 SV=1
Length = 1266
Score = 238 bits (606), Expect = 6e-60, Method: Compositional matrix adjust.
Identities = 178/560 (31%), Positives = 257/560 (45%), Gaps = 40/560 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ IH CA+ CG+ S G L CP + P K+ SLC TGN
Sbjct: 22 AQGETKIHEEGRCAIRGHCGKLSFFGGQLPCPDNGLAKAPTADTRKKLVSLCGDKWKTGN 81
Query: 87 VCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDL 146
VCC + Q+ A I+ CPAC NF NLFC +CSP+QSLFINVT V V +D
Sbjct: 82 VCCEDPQM-AEGIIASCPACKENFFNLFCSFTCSPDQSLFINVTQTDTVKDKKVVTELDN 140
Query: 147 YVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSID 206
+E + G Y +CKDVK G +A+DF+G GA N+ ++ FLG K GSP+ I+
Sbjct: 141 LWSEVYQVGFYDSCKDVKNGASGGKAMDFIGGGARNFTQFLKFLGDK---KLLGSPFQIN 197
Query: 207 FKTT---ILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
F T +D+ M+ + + SC+D +
Sbjct: 198 FMTQPKGPMDAG-MQPLPTTPKSCSDADQKYRCSCIDCPAVCPQLPALPEESYCHVRHL- 255
Query: 264 SLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGE 323
C+ S+ ++Y V + ++ L+ + P D E
Sbjct: 256 ----PCLSFSVIIVYSVFLLLMVAATLVHVVFRKRQQRKLERARLLQDTS-----PSDDE 306
Query: 324 ---VLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA---ARRPTIVLCSSLAIVILLCFGL 377
L+ D + Q S+ + S F A+ R AR P + + +S+ + LL G
Sbjct: 307 DEGDLIDDAGLLDRPQVSY--KLNSVFDAAFSRLGGVCARFPALTITTSIIVCGLLSLGW 364
Query: 378 LRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ--LIIATLPESEHGKPPSIVT 435
LRF VE P KLWV P S AA EK FFD + PFYR EQ LI T P+ P +++
Sbjct: 365 LRFTVERDPVKLWVSPTSAAAREKAFFDENFGPFYRAEQAFLINDTHPDG----PGPVLS 420
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
+ + F+++ +V + + GL +L D+C KP G C QS+ YF N D
Sbjct: 421 YETLSWWFDVENRVRRMISLEKGL--ALEDVCFKPTGHACVVQSLTGYFGGSFSNVDPNN 478
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKV 554
H +YC + S E C F+ PL+P LGG+ N +A+A ++T+ VNN
Sbjct: 479 WKSHLKYCAESPGSIE-CLPDFQQPLKPEMILGGYGQTKNVLDATALVVTWVVNNHAPGS 537
Query: 555 GDENGKAIAWEKAFIQLAKV 574
+E G A+ WE + ++ +V
Sbjct: 538 ENEAG-AVDWEDSLKRVLEV 556
>E4ZXV1_LEPMJ (tr|E4ZXV1) Similar to patched sphingolipid transporter (Ncr1)
OS=Leptosphaeria maculans (strain JN3 / isolate v23.1.3
/ race Av1-4-5-6-7-8) GN=LEMA_P111150.1 PE=4 SV=1
Length = 1372
Score = 237 bits (605), Expect = 8e-60, Method: Compositional matrix adjust.
Identities = 158/553 (28%), Positives = 257/553 (46%), Gaps = 32/553 (5%)
Query: 25 PSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT- 82
P+L ++ S H CA+ CG++ G L CP + P + K+ +C
Sbjct: 119 PALAGPDLT-SKHEAGRCAIRGHCGKQGFFGSDLPCPDNGLATTPEAGVRKKLVDICGPQ 177
Query: 83 -ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS 133
+VCC EEQL +A PI+ CPAC NF N+FC +CSP+QSLFINVT
Sbjct: 178 WADTDVCCVEEQLDALKTNLDRATPIINACPACKENFYNMFCTFTCSPDQSLFINVTQTE 237
Query: 134 QVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQK 193
V +D V++ + Y +CKDVKFG N +A+DF+G GA NY ++ FLG K
Sbjct: 238 PKGDKFLVTELDNLVSDKYASTFYDSCKDVKFGATNGKAMDFIGGGAKNYTQFLKFLGDK 297
Query: 194 VPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
F GSP+ I+F ++ P ME M+ Y C DT
Sbjct: 298 ---KFLGSPFQINFPRPSKNAFPGMEAMDKDAYPC-DTDDELYRCACLDCGGSCTELPEV 353
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
+ + + C+ ++ ++Y ++ +L + S L+ +
Sbjct: 354 REEKKCYVGL----LPCLSFTVIIIYSAIIGLLCMAVTLHIGLKKHSQNKSERMRLLHDL 409
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
++ +G+++ ++ FI W + G AR P I + +S+ +V L
Sbjct: 410 EP-SDDEDEGDIVHNVGMLDRPTKHYFINTWCDRTFSRLGYICARFPVITIVTSIIVVGL 468
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
+ G +RF +ET P LWV P+S AA++K FFD PF+R EQ + G
Sbjct: 469 MSLGWMRFEIETDPVNLWVSPDSAAAQDKAFFDEKFGPFFRAEQAFLVNDTNESSG---P 525
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
+++ + ++ F ++ ++ +++ +G ++L +C KP+G+ C QS+ Y+Q D F
Sbjct: 526 VLSYETLDWWFGVESQIQRLKSYKTG--ITLDQVCFKPIGDACVVQSVTGYWQGD---FA 580
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALT 552
N G AE + + C F+ PL+P GG + + +A A ++T+ V N
Sbjct: 581 NVGPDSWAEELQECVNNPTQCLPTFQQPLDPHVIFGGVN-ESVLDAKALVVTWVVQNH-P 638
Query: 553 KVGDENGKAIAWE 565
K E KA+ +E
Sbjct: 639 KGTPEEQKAMDFE 651
>C5GGT7_AJEDR (tr|C5GGT7) Patched sphingolipid transporter OS=Ajellomyces
dermatitidis (strain ER-3 / ATCC MYA-2586) GN=BDCG_03452
PE=4 SV=1
Length = 1274
Score = 237 bits (604), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 178/581 (30%), Positives = 262/581 (45%), Gaps = 43/581 (7%)
Query: 14 LLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLL 72
LL VL+++ + AQ IH CA+ CG++S G L CP + P
Sbjct: 8 LLGVLVVA--QSNSVFAQGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNGLAKAPAAET 65
Query: 73 SAKIQSLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPN 122
K+ +LC TGNVCC + Q+ A+ I+ CPAC NF NLFC +CSP+
Sbjct: 66 RRKLVALCGDKWKTGNVCCEDTQIDALSSNLKMAEGIIASCPACKENFFNLFCSFTCSPD 125
Query: 123 QSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANN 182
QSLFINVT +V G V +D +E + G Y +CKDVK G +A+DF+G GA N
Sbjct: 126 QSLFINVTQTDKVKGKKVVTELDNLWSEVYQVGFYGSCKDVKNGASGGKAMDFIGGGAKN 185
Query: 183 YKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP----MELMNASVYSCNDTSLGXXXXX 238
Y + FLG K GSP+ I+F T + P M + SC+D+
Sbjct: 186 YSRFLKFLGDK---KLLGSPFQINFVTE--PNGPGDVGMRPLPEIPKSCSDSD---QKYR 237
Query: 239 XXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXX 298
+G L C+ S+ ++Y V + +L
Sbjct: 238 CSCVDCPAVCPRLPALEEETYCHVGHLP--CLSFSVIIIYSVFLLLLVAGTLGHFVFQRR 295
Query: 299 XXGSSAEPLLVSEGRSFTNLPKDGE---VLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRW 354
L+ + P D E L+ D + Q S+ + + G
Sbjct: 296 QQRKLERARLLQD-----TSPSDDEDEGDLIDDAGILDRPQTSYKLNSVFDAIFNRLGGA 350
Query: 355 AARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRI 414
AR P + + +S+ +L G LRF VET P +LWV P S AA+EK FFD + PFYR
Sbjct: 351 CARFPALTITTSIIFCGVLSLGWLRFAVETDPVRLWVSPSSAAAQEKAFFDENFGPFYRA 410
Query: 415 EQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED 474
EQ + ++ P +++ + + F+++ +V + + GL SL DIC P G+
Sbjct: 411 EQAFLVN--DTHPNGPGPVLSYETLSWWFDVESRVRRMISLDKGL--SLDDICFNPTGKA 466
Query: 475 CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-N 533
C QS+ YF N D +H +C + + + C F+ PL+P LGG+
Sbjct: 467 CVVQSLTGYFGGSFSNVDPNTWEDHLRHCTESPGAVD-CLPDFQQPLKPEMILGGYGRPG 525
Query: 534 NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
N ASA ++T+ VNN E G AI WE + ++ +V
Sbjct: 526 NVLNASALVVTWVVNNHAPGSKAEAG-AIDWEDSLKRVLEV 565
>C5JHY3_AJEDS (tr|C5JHY3) Patched sphingolipid transporter OS=Ajellomyces
dermatitidis (strain SLH14081) GN=BDBG_02112 PE=4 SV=1
Length = 1274
Score = 237 bits (604), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 178/581 (30%), Positives = 262/581 (45%), Gaps = 43/581 (7%)
Query: 14 LLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLL 72
LL VL+++ + AQ IH CA+ CG++S G L CP + P
Sbjct: 8 LLGVLVVA--QSNSVFAQGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNGLAKAPAAET 65
Query: 73 SAKIQSLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPN 122
K+ +LC TGNVCC + Q+ A+ I+ CPAC NF NLFC +CSP+
Sbjct: 66 RRKLVALCGDKWKTGNVCCEDTQIDALSSNLKMAEGIIASCPACKENFFNLFCSFTCSPD 125
Query: 123 QSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANN 182
QSLFINVT +V G V +D +E + G Y +CKDVK G +A+DF+G GA N
Sbjct: 126 QSLFINVTQTDKVKGKKVVTELDNLWSEVYQVGFYGSCKDVKNGASGGKAMDFIGGGAKN 185
Query: 183 YKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP----MELMNASVYSCNDTSLGXXXXX 238
Y + FLG K GSP+ I+F T + P M + SC+D+
Sbjct: 186 YSRFLKFLGDK---KLLGSPFQINFVTE--PNGPGDVGMRPLPEIPKSCSDSD---QKYR 237
Query: 239 XXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXX 298
+G L C+ S+ ++Y V + +L
Sbjct: 238 CSCVDCPAVCPRLPALEEESYCHVGHLP--CLSFSVIIIYSVFLLLLVAGTLGHFVFQRR 295
Query: 299 XXGSSAEPLLVSEGRSFTNLPKDGE---VLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRW 354
L+ + P D E L+ D + Q S+ + + G
Sbjct: 296 QQRKLERARLLQD-----TSPSDDEDEGDLIDDAGILDRPQTSYKLNSVFDAIFNRLGGA 350
Query: 355 AARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRI 414
AR P + + +S+ +L G LRF VET P +LWV P S AA+EK FFD + PFYR
Sbjct: 351 CARFPALTITTSIIFCGVLSLGWLRFAVETDPVRLWVSPSSAAAQEKAFFDENFGPFYRA 410
Query: 415 EQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED 474
EQ + ++ P +++ + + F+++ +V + + GL SL DIC P G+
Sbjct: 411 EQAFLVN--DTHPNGPGPVLSYETLSWWFDVESRVRRMISLDKGL--SLDDICFNPTGKA 466
Query: 475 CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-N 533
C QS+ YF N D +H +C + + + C F+ PL+P LGG+
Sbjct: 467 CVVQSLTGYFGGSFSNVDPNTWEDHLRHCTESPGAVD-CLPDFQQPLKPEMILGGYGRPG 525
Query: 534 NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
N ASA ++T+ VNN E G AI WE + ++ +V
Sbjct: 526 NVLNASALVVTWVVNNHAPGSKAEAG-AIDWEDSLKRVLEV 565
>F2T222_AJEDA (tr|F2T222) Patched sphingolipid transporter OS=Ajellomyces
dermatitidis (strain ATCC 18188 / CBS 674.68)
GN=BDDG_00443 PE=4 SV=1
Length = 1274
Score = 237 bits (604), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 178/581 (30%), Positives = 262/581 (45%), Gaps = 43/581 (7%)
Query: 14 LLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLL 72
LL VL+++ + AQ IH CA+ CG++S G L CP + P
Sbjct: 8 LLGVLVVA--QSNSVFAQGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNGLAKAPAAET 65
Query: 73 SAKIQSLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPN 122
K+ +LC TGNVCC + Q+ A+ I+ CPAC NF NLFC +CSP+
Sbjct: 66 RRKLVALCGDKWKTGNVCCEDTQIDALSSNLKMAEGIIASCPACKENFFNLFCSFTCSPD 125
Query: 123 QSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANN 182
QSLFINVT +V G V +D +E + G Y +CKDVK G +A+DF+G GA N
Sbjct: 126 QSLFINVTQTDKVKGKKVVTELDNLWSEVYQVGFYGSCKDVKNGASGGKAMDFIGGGAKN 185
Query: 183 YKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP----MELMNASVYSCNDTSLGXXXXX 238
Y + FLG K GSP+ I+F T + P M + SC+D+
Sbjct: 186 YSRFLKFLGDK---KLLGSPFQINFVTE--PNGPGDVGMRPLPEIPKSCSDSD---QKYR 237
Query: 239 XXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXX 298
+G L C+ S+ ++Y V + +L
Sbjct: 238 CSCVDCPAVCPRLPALEEESYCHVGHLP--CLSFSVIIIYSVFLLLLVAGTLGHFVFQRR 295
Query: 299 XXGSSAEPLLVSEGRSFTNLPKDGE---VLVIDPQRQNEVQYSF-IQEWLSNFYRAYGRW 354
L+ + P D E L+ D + Q S+ + + G
Sbjct: 296 QQRKLERARLLQD-----TSPSDDEDEGDLIDDAGILDRPQTSYKLNSVFDAIFNRLGGA 350
Query: 355 AARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRI 414
AR P + + +S+ +L G LRF VET P +LWV P S AA+EK FFD + PFYR
Sbjct: 351 CARFPALTITTSIIFCGVLSLGWLRFAVETDPVRLWVSPSSAAAQEKAFFDENFGPFYRA 410
Query: 415 EQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED 474
EQ + ++ P +++ + + F+++ +V + + GL SL DIC P G+
Sbjct: 411 EQAFLVN--DTHPNGPGPVLSYETLSWWFDVESRVRRMISLDKGL--SLDDICFNPTGKA 466
Query: 475 CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-N 533
C QS+ YF N D +H +C + + + C F+ PL+P LGG+
Sbjct: 467 CVVQSLTGYFGGSFSNVDPNTWEDHLRHCTESPGAVD-CLPDFQQPLKPEMILGGYGRPG 525
Query: 534 NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
N ASA ++T+ VNN E G AI WE + ++ +V
Sbjct: 526 NVLNASALVVTWVVNNHAPGSKAEAG-AIDWEDSLKRVLEV 565
>M1VVZ0_CLAPU (tr|M1VVZ0) Related to human PTC protein involved in nevoid basal
cell carcinoma syndrome OS=Claviceps purpurea 20.1
GN=CPUR_04205 PE=4 SV=1
Length = 1276
Score = 237 bits (604), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 157/542 (28%), Positives = 256/542 (47%), Gaps = 33/542 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA CG++S GK L C + P L ++ LC G VCCT +Q
Sbjct: 31 HEAGRCAFRGQCGKQSLFGKELPCVDNDLAQDPDAELRQELVDLCGADWSDGPVCCTLDQ 90
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ +G CPAC NF N+FC+ +CSP+QSLF+NVT + + + V +D
Sbjct: 91 VRSLKSELGTPNTLIGSCPACKHNFFNMFCKFTCSPDQSLFVNVTQAAPKNDKLLVTELD 150
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E +G G Y +CK+VKFG N+RA+D +G GA NY + FLG K P GSP+ I
Sbjct: 151 QLISEKYGSGFYDSCKEVKFGGANSRAMDLIGGGAKNYHDMLKFLGDKKP--LVGSPFQI 208
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
++ + D S M ++ + CND ++G+L
Sbjct: 209 NYPESYEDPS-MGALDMTPKKCNDED---PNFRCVCVDCPEMCPKLPDVEESGSCRVGAL 264
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + Y +L+F I L+ E + + G VL
Sbjct: 265 P--CLSFASIFTYSILLFAFSATIFGHVAWKRYAQHRFERTRLLHEALHSDDEDEGGPVL 322
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R + +I + + + G ++R P I + SL IV +L G +F++E
Sbjct: 323 T-EAMRDRPTKRYWINDRCDDLFYRLGHASSRFPGITIGVSLLIVAILSAGWFKFDLEKD 381
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA--TLPESEHGKPPSIVTDDNIELLF 443
P +LWV P S AA+EK +FD++ PFYR E++ + TLP P +++ D ++
Sbjct: 382 PARLWVSPSSAAAQEKAYFDANFGPFYRSEKIFLVNDTLPSG----PGPVLSYDTLKWWM 437
Query: 444 EIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYC 503
++++ ++ + ++ G L D+C KP+G+ C QS+ Y+ + +H C
Sbjct: 438 DVEKSIETLESDTYGKY--LGDLCFKPMGDACVVQSVTGYWFPQGGEINAKTWKDHLRKC 495
Query: 504 FQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
+ S C F P++P+ LGG+ + +EA A +T+ +NN + D G AI
Sbjct: 496 TE---SPVDCRPKFGQPIDPSMILGGYD-EDVTEAQALTVTWVINNP-PEGSDARGTAID 550
Query: 564 WE 565
WE
Sbjct: 551 WE 552
>J9MSV5_FUSO4 (tr|J9MSV5) Uncharacterized protein OS=Fusarium oxysporum f. sp.
lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL
34936) GN=FOXG_05987 PE=4 SV=1
Length = 1315
Score = 236 bits (601), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 165/547 (30%), Positives = 255/547 (46%), Gaps = 38/547 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P + L ++ LC TG VCC+ +Q
Sbjct: 29 HEAGRCAFRGHCGKQSFFGKELPCVDNGLAEDPDEELRNELVELCGQKWKTGPVCCSLDQ 88
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++A+ +G CPAC NF NLFC +CSP+QSLFINVT + +G V +D
Sbjct: 89 IKALKSELGTPSTLIGSCPACKDNFFNLFCTFTCSPDQSLFINVTDSAPKNGKKLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E +G G Y +CK+VKFG N++A+D +G GA NY E FLG K P GSP+ I
Sbjct: 149 QLISEKYGSGFYDSCKEVKFGGANSKAMDLIGGGAKNYTEMLKFLGDKKP--LVGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T D + ++ + CND ++G L
Sbjct: 207 NFPTDYSDRD-LHPLDMTPKKCNDED---PDYRCVCVDCPGVCPKLPDVKDSKSCRVGLL 262
Query: 266 KVRCVDLS----LAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKD 321
C+ + +VL + L+ +FG I E + S ++ +
Sbjct: 263 P--CLSFASIFVYSVLLLTLILAVFGHIAYKKYSQ-----HRVERTRLLHESSHSDDEDE 315
Query: 322 GEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFN 381
G + + R+ + ++ + + G AAR P + SL V +L GL RF+
Sbjct: 316 GGPVDTEAMRERPTKRYWVNDKCDKAFYQLGHIAARFPGWCIGLSLLFVAILSVGLFRFD 375
Query: 382 VETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIEL 441
+E P +LWV P S AA+EK +FDS+ PFYR E++ + +++ P ++T D ++
Sbjct: 376 LEKEPARLWVSPSSAAAQEKAYFDSNFGPFYRAEKVFLVN--DTDPSGPGPVLTYDTLKW 433
Query: 442 LFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAE 501
E++E V +I + G L D+C KP + C QS+ Y+ FD E
Sbjct: 434 WIEVEESVKKIESPVYGKY--LQDLCFKPSNDACVVQSVSAYWHAK-GGFDPKYWKEDLR 490
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
C + S C F P+EP GG+ ++ +A A +T+ VNNA + D +A
Sbjct: 491 ACAK---SPVDCRPDFGQPIEPNMIFGGYD-DDVVDAHAITVTWVVNNA-QEGTDALARA 545
Query: 562 IAWEKAF 568
+ WE +
Sbjct: 546 VDWENSL 552
>N1Q8U7_9PEZI (tr|N1Q8U7) Uncharacterized protein OS=Pseudocercospora fijiensis
CIRAD86 GN=MYCFIDRAFT_201879 PE=4 SV=1
Length = 1272
Score = 235 bits (600), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 173/556 (31%), Positives = 258/556 (46%), Gaps = 41/556 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA+ CG++ G L CP + +P + L K+ SLC NVCC EEQ
Sbjct: 24 HEKGRCALRGNCGKQGFFGSELPCPDNGLAEEPEEKLRDKLVSLCGDEWKDTNVCCREEQ 83
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
L +A IL C AC +NF +LFC +CSP+QS+F+NVT + V +D
Sbjct: 84 LDTLKSNLDKANSILSSCGACKKNFYDLFCTFTCSPDQSVFVNVTDTAAKGDKFLVTEVD 143
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+++ +GEG Y +CK+VKFG +A+DF+G GA NY + + G K P F GSP+ I
Sbjct: 144 QLISDKYGEGFYDSCKEVKFGATGGKAMDFIGGGAKNYTQMLKYQGDKKP--FLGSPFQI 201
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F M+ + + CN T +G +
Sbjct: 202 NFPRPSEGFPGMDTILDTPIPCNTTD---EQYRCACVDCPGSCPELPEVTSTEECHVGLM 258
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ ++ ++Y V V +L I S E L + + S ++ +G+++
Sbjct: 259 P--CLSFAVVLIYSVFVVLLVLAISGHVAAAKRRR-SKNEQLQLLQDDSPSDDEDEGDMV 315
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ + + + GR A+ P I + +S+ IV LLC G RF+VET
Sbjct: 316 HSAGMLDRPTKQYAVNTYCDRIFSHLGRVCAQFPAITISTSVVIVGLLCIGWARFDVETD 375
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P KLWV P+S AA EK+FFD H PF+R EQ + E P +++ + + F++
Sbjct: 376 PVKLWVAPDSNAAIEKQFFDDHFGPFFRAEQAFLVNDQHPEGNGP--VLSYNTLAWWFDV 433
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYF---QMDPDNFDNYGGVEHAEY 502
+ ++ ++ SG +L D+C P G+ C QSI +F +DP +D E +
Sbjct: 434 ERRIRVQKSLGSGY--TLKDVCYNPTGDACVVQSISGWFAQSALDPSTWD-----EQVKK 486
Query: 503 CFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSE----ASAFIITYPVNNALTKVGDEN 558
C E C FK PL LGG+ N SE ASA I T+ V N GD N
Sbjct: 487 CAGSPGDPE-CLPEFKLPLSSERVLGGY--NRTSEPATNASALITTWVVQN--FNPGDPN 541
Query: 559 -GKAIAWEKAFIQLAK 573
KA WE++ +L K
Sbjct: 542 LKKAEEWEESMKRLLK 557
>G1XTC9_ARTOA (tr|G1XTC9) Uncharacterized protein OS=Arthrobotrys oligospora
(strain ATCC 24927 / CBS 115.81 / DSM 1491)
GN=AOL_s00215g58 PE=4 SV=1
Length = 1292
Score = 235 bits (599), Expect = 4e-59, Method: Compositional matrix adjust.
Identities = 163/550 (29%), Positives = 257/550 (46%), Gaps = 41/550 (7%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H ++YCA+ D CGQR GK L CP P+ +P L + C G VCCT+ Q
Sbjct: 41 HKSDYCAIRDECGQRGWFGKPLPCPDNGPAKEPSASLRKDLVDFCGQKWAEGAVCCTDNQ 100
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
L+ + +L CPAC NF NL C ++CSPNQS F+NVT + GN V +
Sbjct: 101 LETMKGNLEVVQQLLAPCPACKANFFNLVCTMTCSPNQSQFLNVTKTETLSGNEVVAELS 160
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
YV ++G G + +CK+VKF ++F+G A + E+ FLG + P GSP+ I
Sbjct: 161 YYVDPSYGRGFFDSCKNVKFSQTGGSVMEFIGGNAKTWPEFLKFLGDEKP---IGSPFQI 217
Query: 206 DF---KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
++ T +P++ MN + CND + ++
Sbjct: 218 NYVLNDDTPTPPNPIKAMNDPIIKCNDPN---PAYSCSCLDCAEACPKLPDLEDEKACRV 274
Query: 263 GSLKVRCVDLSLAVLYIVL---VFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLP 319
G + C+ S+ V+Y V + + +G+ LL +G S +
Sbjct: 275 GIIP--CLSFSVIVIYAVFLTAILLCYGYFFTRDYTHRYQRLR----LLHDDGPS--DDE 326
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
+G++L + + L N ++ G A P + + S+ +++L+ G L
Sbjct: 327 DEGDILAPAGFSDHPASEYPLNVKLDNAFQKLGYGCATYPGLTIGISVIVIVLMSLGWLN 386
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F VET P KLWV P S+ A +K+FFD + PF+RIEQ A L G+P +++ D +
Sbjct: 387 FQVETNPVKLWVSPTSETALQKDFFDQNFGPFWRIEQ---AFLVNDVSGEPQPVLSYDTL 443
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
+ F ++ V +++ G V+L DIC P G CA QSI +F PD +
Sbjct: 444 QWWFNVESTVKRMKSLEEG--VALPDICFNPTGAGCAIQSISGWFDERPDLLNPSDWDTR 501
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDEN 558
+ C + +S C A PL+P LGG+ S + + A ++++ VNN + E
Sbjct: 502 IKDCAANPSS---CLPAMGQPLDPEVVLGGYTSTDKVLDVPAIMVSWVVNNH-PEGSKEV 557
Query: 559 GKAIAWEKAF 568
KA+ WE++
Sbjct: 558 KKAMDWEESL 567
>F9X956_MYCGM (tr|F9X956) NCR1, Niemann-pick type C OS=Mycosphaerella graminicola
(strain CBS 115943 / IPO323) GN=NCR1 PE=4 SV=1
Length = 1282
Score = 234 bits (598), Expect = 5e-59, Method: Compositional matrix adjust.
Identities = 180/585 (30%), Positives = 275/585 (47%), Gaps = 39/585 (6%)
Query: 4 MSTAIISVGFLLQVLILSWFSPSLTAAQISRSI---HSNEYCAMYDICGQRSD-GKVLNC 59
M T ++ G+LL L + SP LTAA S + H CA+ CG++ GK L C
Sbjct: 1 MRTGSVT-GWLLSGLAV--ISP-LTAAAASPDLTTKHEAGRCAIRGNCGKQGFFGKQLPC 56
Query: 60 PYPSPSVKPHDLLSAKIQSLCPTITGN--VCCTEEQLQAVP--------ILVGCPACLRN 109
P + +P + + ++ S+C + VCC EQL A+ ++ C AC +N
Sbjct: 57 PDNYLAEEPSEDVRKQLVSICGEEWSDTKVCCKAEQLDALESNLKTANRLISSCGACKKN 116
Query: 110 FLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMN 169
F +LFC +CSP+QSLF+N+T D V +D V++ FG G YS+CKDV FG
Sbjct: 117 FYDLFCTFTCSPDQSLFVNITQTEPKDDKFMVTELDQLVSDDFGAGFYSSCKDVTFGATG 176
Query: 170 TRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCND 229
++ +DF G G+ NY + FLG+K P G SP+ I+F ME + CN
Sbjct: 177 SKVMDFFG-GSKNYTDLLTFLGKKSPFG---SPFQINFPRPSEGFPNMETVLKDPKPCNS 232
Query: 230 TSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWI 289
T +G L C+ ++ ++Y ++ +L +
Sbjct: 233 TE---EIYRCACVDCEGSCPALPAIHEAEQCHVGLLP--CLSFAIVIVYSTIIALLVLAV 287
Query: 290 XXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYR 349
S E L + + S ++ +G+V + + ++ +
Sbjct: 288 TGHVAAAKRRQ-SKNERLQLLQDASPSDDEDEGDVGYNGNMLDRPTKQYVVNTFVDRMFS 346
Query: 350 AYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLA 409
GR + P I + SS+ +V LL G +RF +ET P KLWV P+S AA EKEFFD++
Sbjct: 347 RLGRTCSNFPAITISSSVLVVALLSLGWIRFALETDPVKLWVSPDSDAAREKEFFDTNFG 406
Query: 410 PFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLK 469
PF+R EQ + S+ G P +++ D + F+++ +V ++ G +L D+C
Sbjct: 407 PFFRAEQAFLVNDTASKLGHSP-VLSYDTLSWWFDVERRVSVQKSLEHGY--TLKDVCYN 463
Query: 470 PLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGG 529
P GE C QS+ Y+ + D + EH C + T +TC AFK PL LGG
Sbjct: 464 PTGEACIVQSVSGYYASESFQKDTWE--EHLRTCTETNTD-QTCLPAFKQPLPVERLLGG 520
Query: 530 FSGNNYS--EASAFIITYPVNNALTKVGDEN-GKAIAWEKAFIQL 571
F N S +ASA I T+ V N G+ KA WE++F +L
Sbjct: 521 FDRANQSALQASALITTWVVTN--YNPGEPGLAKAEEWEESFKRL 563
>F9FNX7_FUSOF (tr|F9FNX7) Uncharacterized protein OS=Fusarium oxysporum (strain
Fo5176) GN=FOXB_08107 PE=4 SV=1
Length = 1323
Score = 234 bits (597), Expect = 7e-59, Method: Compositional matrix adjust.
Identities = 163/543 (30%), Positives = 252/543 (46%), Gaps = 30/543 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P + L ++ LC TG VCC+ +Q
Sbjct: 29 HEAGRCAFRGHCGKQSFFGKELPCVDNGLAEDPDEELRNELVELCGQKWKTGPVCCSLDQ 88
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++A+ +G CPAC NF NLFC +CSP+QSLFINVT + +G V +D
Sbjct: 89 IKALKSELGTPSTLIGSCPACKDNFFNLFCTFTCSPDQSLFINVTDSAPKNGKKLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E +G G Y +CK+VKFG N++A+D +G GA NY E FLG K P GSP+ I
Sbjct: 149 QLISEKYGSGFYDSCKEVKFGGANSKAMDLIGGGAKNYTEMLKFLGDKKP--LVGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T D + ++ + CND ++G L
Sbjct: 207 NFPTDYSDRD-LHPLDMTPKKCNDED---PDYRCVCVDCPGVCPKLPDVKDSKSCRVGLL 262
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + +Y VL+ L + L+ E S ++ +G +
Sbjct: 263 P--CLSFASIFVYSVLLLTLILAVFGHIAYKKYSQHRVERTRLLHES-SHSDDEDEGGPV 319
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R+ + ++ + + G AAR P + SL V +L GL RF++E
Sbjct: 320 DTEAMRERPTKRYWVNDKCDKAFYQLGHIAARFPGWCIGLSLLFVAILSVGLFRFDLEKE 379
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FDS+ PFYR E++ + +++ P ++T D ++ E+
Sbjct: 380 PARLWVSPSSAAAQEKAYFDSNFGPFYRAEKVFLVN--DTDPSGPGPVLTYDTLKWWIEV 437
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
+E V +I + G D+C KP + C QS+ Y+ FD E C +
Sbjct: 438 EESVKKIESPVYGKY--FQDLCFKPSNDACVVQSVSAYWHAK-GGFDPKYWKEDLRACAK 494
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
S C F P+EP GG+ ++ +A A +T+ VNNA + D +A+ WE
Sbjct: 495 ---SPVDCRPDFGQPIEPNMIFGGYD-DDVVDAHAITVTWVVNNA-QEGTDALARAVDWE 549
Query: 566 KAF 568
+
Sbjct: 550 NSL 552
>N4U1F7_FUSOX (tr|N4U1F7) Niemann-Pick type C-related protein 1 OS=Fusarium
oxysporum f. sp. cubense race 1 GN=FOC1_g10012010 PE=4
SV=1
Length = 1315
Score = 234 bits (597), Expect = 7e-59, Method: Compositional matrix adjust.
Identities = 162/543 (29%), Positives = 250/543 (46%), Gaps = 30/543 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P + L ++ LC TG VCC+ +Q
Sbjct: 29 HEAGRCAFRGHCGKQSFFGKELPCVDNGLAEDPDEELRNELVELCGQKWKTGPVCCSLDQ 88
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++A+ +G CPAC NF NLFC +CSP+QSLFINVT + +G V +D
Sbjct: 89 IKALKSELGTPSTLIGSCPACKDNFFNLFCTFTCSPDQSLFINVTDSAPKNGKKLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++E +G G Y +CK+VKFG N++A+D +G GA NY E FLG K P GSP+ I
Sbjct: 149 QLISEKYGSGFYDSCKEVKFGGANSKAMDLIGGGAKNYTEMLKFLGDKKP--LVGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T D + ++ + CND + L
Sbjct: 207 NFPTDYSDRD-LHPLDMTPKKCNDEDPDYRCVCVDCPGVCPKLPDVKDSKSCRVGLLPCL 265
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
+ +VL + L+ +FG I E + S ++ +G +
Sbjct: 266 SFASI-FVYSVLLLTLILAVFGHIAYKKYSQ-----HRVERTRLLHESSHSDDEDEGGPV 319
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R+ + ++ + + G AAR P + SL V +L GL RF++E
Sbjct: 320 DTEAMRERPTKRYWVNDKCDKAFYQLGHIAARFPGWCIGLSLLFVAILSVGLFRFDLEKE 379
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FDS+ PFYR E++ + +++ P ++T D ++ E+
Sbjct: 380 PARLWVSPSSAAAQEKAYFDSNFGPFYRAEKVFLVN--DTDPSGPGPVLTYDTLKWWIEV 437
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
+E V +I + G D+C KP + C QS+ Y+ FD E C +
Sbjct: 438 EESVKKIESPVYGKY--FQDLCFKPSNDACVVQSVSAYWHAK-GGFDPKYWKEDLRACAK 494
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
S C F P+EP GG+ ++ +A A +T+ VNNA + D +A+ WE
Sbjct: 495 ---SPVDCRPDFGQPIEPNMIFGGYD-DDVVDAHAITVTWVVNNA-QEGTDALARAVDWE 549
Query: 566 KAF 568
+
Sbjct: 550 NSL 552
>K3VY67_FUSPC (tr|K3VY67) Uncharacterized protein OS=Fusarium pseudograminearum
(strain CS3096) GN=FPSE_09646 PE=4 SV=1
Length = 1273
Score = 234 bits (596), Expect = 8e-59, Method: Compositional matrix adjust.
Identities = 165/547 (30%), Positives = 255/547 (46%), Gaps = 38/547 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H + CA CG++S GK L C + P + L ++ LC TG VCCT +Q
Sbjct: 29 HESGRCAFRGHCGKQSFFGKELPCVDNGLAEDPEEELRNELVGLCGEKWRTGPVCCTLDQ 88
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ +G CPAC NF NLFC +CSP+QS FINVT + +G V +D
Sbjct: 89 VKSLKSELGTPNTLIGSCPACKDNFFNLFCTFTCSPDQSTFINVTDSAPKNGKNLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+E +G G Y +CK+VKFG N+RA+D +G GA NY E FLG K P F GSP+ I
Sbjct: 149 HLVSEKYGSGFYDSCKEVKFGGANSRAMDLIGGGAKNYTEMLTFLGNKKP--FAGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T ++ ++ CND K+G L
Sbjct: 207 NFPTQ-QKVPKLQPVDMKPKKCNDED---PNYRCVCVDCPEVCAKLPEVKDSKSCKVGLL 262
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + +Y VLV L + L+ E S ++ +G +
Sbjct: 263 P--CLSFASIFVYGVLVSTLILAVTGHIAYQKYSQHRVERTRLLHES-SHSDDEDEGGPV 319
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R+ + ++ + + G AAR P + SL V +L GL RF++E
Sbjct: 320 DTEAMRERPTKRYWVNDRCDRGFYQLGHIAARFPGWCIGLSLLFVGILSIGLFRFDLEKE 379
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FD + PFYR E++ +A ++ P +++ D ++ E+
Sbjct: 380 PARLWVSPSSAAAQEKAYFDENFGPFYRAEKIFLAN--DTNPSGPGPVLSYDTLKWWIEV 437
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQ----MDPDNFDNYGGVEHAE 501
+E V +I + G D+C KP + C QS+ Y+ ++P+ + +
Sbjct: 438 EESVKKIESPVYGKY--FQDLCFKPSNDACVVQSVSAYWHSKGGLEPETWK-----DDIR 490
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
C + S C F P+EP GG+ G++ +A A +T+ VNNA + D +A
Sbjct: 491 ACAK---SPVDCRPDFGQPIEPNMIFGGY-GDDIVDAHAITVTWVVNNA-KEGTDAIARA 545
Query: 562 IAWEKAF 568
+ WE A
Sbjct: 546 VDWETAL 552
>R1GF75_9PEZI (tr|R1GF75) Putative patched sphingolipid transporter protein
OS=Neofusicoccum parvum UCRNP2 GN=UCRNP2_2942 PE=4 SV=1
Length = 1279
Score = 234 bits (596), Expect = 1e-58, Method: Compositional matrix adjust.
Identities = 161/549 (29%), Positives = 244/549 (44%), Gaps = 34/549 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA+ CG G L CP + P + K+ S+C +VCC +EQ
Sbjct: 34 HEKGRCALRGHCGSEGFFGPQLPCPDNGLAKTPEPDVREKLVSICGDKWADSDVCCEDEQ 93
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
+ A+ ++ CPAC NF NLFC +CSP+QSLF+NVT +G + V +
Sbjct: 94 IDALQSNLKRAESLIASCPACKENFFNLFCTFTCSPDQSLFVNVTDTKSKNGKLMVTELT 153
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V++ +G Y++CKDVK G N A+D +G GA NY + FLG K F GSP+ +
Sbjct: 154 HLVSDDYGSRFYNSCKDVKVGATNGNAMDLIGGGAKNYTRFLKFLGDK---KFLGSPFQM 210
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F L ++ +CND+ +G L
Sbjct: 211 NFPDPSLYPG-LKPQTKGAKACNDSD---EKYRCACVDCPSVCPELPEVKENKRCHVGVL 266
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXX-XXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEV 324
LS AV+ I VF+L I E + + + ++ +G+V
Sbjct: 267 PC----LSFAVIIIYSVFILLLVIAVSGHVAYQKHYQHKQERMRLLQDLEPSDDEDEGDV 322
Query: 325 LVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVET 384
+ + + + +W + G A P + + SS+ +V+LL G LRF VET
Sbjct: 323 VAAAGILETPTRRYKLNDWCDKIFSRLGYTCAEYPALTILSSVTVVVLLSLGWLRFTVET 382
Query: 385 RPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFE 444
P +LWV P+S AAEEK FFD + PFYR EQ + + P +++ D + F+
Sbjct: 383 DPVRLWVAPDSAAAEEKAFFDKNFGPFYRAEQAFLVNDQDPSGAAP--VLSYDTLGWWFD 440
Query: 445 IQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCF 504
++ +V+ + + ++ D+C KP G+ C QS+ YF D N + E C
Sbjct: 441 VERRVNRLMIDG----ITFDDVCFKPTGDACVVQSLTGYFGNDFFNVNPKTWKEDLRACA 496
Query: 505 QHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAW 564
S C F+ PL P LGG+ N +A A I+T+ VNN E A+ W
Sbjct: 497 D---SPVDCLPDFQQPLNPQMLLGGWD-TNVLDAKALIVTWVVNNHQEGT-KELETAMKW 551
Query: 565 EKAFIQLAK 573
E + L +
Sbjct: 552 ENSLKSLLR 560
>G7XA76_ASPKW (tr|G7XA76) Patched sphingolipid transporter OS=Aspergillus
kawachii (strain NBRC 4308) GN=AKAW_01890 PE=4 SV=1
Length = 1277
Score = 233 bits (595), Expect = 1e-58, Method: Compositional matrix adjust.
Identities = 182/583 (31%), Positives = 267/583 (45%), Gaps = 50/583 (8%)
Query: 15 LQVLILSWF--SPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDL 71
L VL SW PSL +IH CA+ CG++S G L CP + +P
Sbjct: 13 LGVLPQSWARDEPSLGFT----NIHEPGRCAIRGHCGKKSFFGGELPCPDNGLAQEPEAA 68
Query: 72 LSAKIQSLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSP 121
+ K+ LC + G VCC +EQ+ A+ I+ CPAC NF N+FC +CSP
Sbjct: 69 VRKKLVDLCGSKWEEGPVCCLDEQIDALSKNLKLAEGIIASCPACKDNFFNIFCTFTCSP 128
Query: 122 NQSLFINVTSISQV-DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGA 180
+QSLF+NVT I + G V ID +E + G Y +CK+VK G +AIDF+G GA
Sbjct: 129 DQSLFVNVTDIDEARGGKQLVTEIDNIWSEEYQSGFYDSCKNVKNGASGGKAIDFIGGGA 188
Query: 181 NNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXX 238
NY ++ FLG K GSP+ I+FKT P M+ + +CND
Sbjct: 189 KNYTQFLKFLGDK---KLLGSPFQINFKTEPAGPVPEGMKPLPIKPKACNDAD---EAFR 242
Query: 239 XXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXX 298
+G L LS AVL I VF+L
Sbjct: 243 CSCVDCPDVCPELPAIETDKYCHVGLLPC----LSFAVLLIYSVFLLVIVAFSSYFTYRE 298
Query: 299 XXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARR 358
E + + + + ++ +G+++ + + L + + G AR
Sbjct: 299 RRYRKPERVRLLQDPAPSDDEDEGDIVRAGGYIEQPNDVYKLNSMLDRVFNSIGGACARF 358
Query: 359 PTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLI 418
P + SS+ +V+LL G RF VET P +LWV P S AA+EK +FD++ PFYR EQ
Sbjct: 359 PGFTIGSSIVMVVLLSLGWFRFAVETDPVRLWVSPTSAAAQEKAYFDANFGPFYRAEQAF 418
Query: 419 IATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQ 478
+ S G S+++ D + F+++ +V + + GL+ L DIC KP GE C Q
Sbjct: 419 LVNDTSSGDG---SVLSYDTLSWWFDVESRVHRMISLDRGLI--LDDICTKPTGEACVIQ 473
Query: 479 SILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-G 532
S+ YF +DPD ++ ++C +C F PL P LGG+
Sbjct: 474 SLTGYFGGSVANLDPDTWE-----ARLKHCADSPGDV-SCLPDFGQPLRPEMILGGYGES 527
Query: 533 NNYSEASAFIITYPVNN-ALTKVGDENGKAIAWEKAFIQLAKV 574
+ +A A I T+ V+N A G+ N AI WE + ++ +V
Sbjct: 528 RDVLDAQALITTWVVDNHAQGTEGEAN--AIDWENSLRRILEV 568
>K9FXB4_PEND1 (tr|K9FXB4) Uncharacterized protein OS=Penicillium digitatum
(strain Pd1 / CECT 20795) GN=PDIP_47020 PE=4 SV=1
Length = 1256
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 171/585 (29%), Positives = 262/585 (44%), Gaps = 80/585 (13%)
Query: 20 LSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQS 78
L F+P L AQ IH CA+ CG++S G L CP + +P D + Q
Sbjct: 13 LGSFAPVLVGAQGETKIHETGRCAIRGHCGKQSIFGGELPCPDNDLAHQPEDTVR---QK 69
Query: 79 LCPTITGNVCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDG 137
L ++ N+ E I+ CPAC NF N+FC +CSP+QSLF+N+T + G
Sbjct: 70 LIDALSSNLKLAEG------IIASCPACRDNFFNIFCTFTCSPDQSLFVNITKTEENSSG 123
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPG 197
V +D ++ + G + +CK+VK G +AIDF+G GA + + FLG K
Sbjct: 124 KRLVTELDNIWSKEYQSGFFDSCKNVKNGASGGKAIDFIGGGAKDDTHFMKFLGDK---K 180
Query: 198 FPGSPYSIDFKT--TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
F GSP+ I++ T + D+ ME ++ +CND
Sbjct: 181 FLGSPFQINYHTEPSGSDTQGMEALSIKPKACNDED------------------------ 216
Query: 256 XXXXIKMGSLKVRCVD------------------------LSLAVLYIVLVFVLFGWIXX 291
S + CVD LS AV+ + +F+LF
Sbjct: 217 -------KSFRCSCVDCPDVCPELPVISPHNICHVGLLPCLSFAVILVYSIFLLFVIALA 269
Query: 292 XXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAY 351
E + + + + ++ +GEV+ + + LS +
Sbjct: 270 SYVTYKERRFRKPERVRLLQDPTPSDDEDEGEVMHRGGYMERSQGVYKLNSVLSTLFHRI 329
Query: 352 GRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPF 411
G AR P I + SS+ V LL G L F+VET P +LWV P S AA+EK+FFD + PF
Sbjct: 330 GGTCARFPAITISSSVIGVALLSLGWLNFDVETDPVRLWVSPSSAAAQEKDFFDQNFGPF 389
Query: 412 YRIEQ-LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKP 470
YR EQ ++ PE++ +P ++ + + F+++ +V + + L + +D+C KP
Sbjct: 390 YRAEQAFLVNNRPEND-SRP--LLDYETLTWWFDVESRVRRVISLDRAL--NFNDVCFKP 444
Query: 471 LGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF 530
GE C QS+ YF N D ++ +C + +C F PL+P LGGF
Sbjct: 445 TGEACVVQSVTGYFGGAVSNLDPDTWMDRLGHCTES-PGDPSCLPDFSQPLKPEMVLGGF 503
Query: 531 SGN-NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
N +A A I+T+ VNN + +E KAI WE F + +V
Sbjct: 504 EDTGNVLDAQALIVTWVVNN-YAQGTEEEAKAIDWENTFQAVLEV 547
>K9FV60_PEND2 (tr|K9FV60) Uncharacterized protein OS=Penicillium digitatum
(strain PHI26 / CECT 20796) GN=PDIG_86050 PE=4 SV=1
Length = 1256
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 171/585 (29%), Positives = 262/585 (44%), Gaps = 80/585 (13%)
Query: 20 LSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQS 78
L F+P L AQ IH CA+ CG++S G L CP + +P D + Q
Sbjct: 13 LGSFAPVLVGAQGETKIHETGRCAIRGHCGKQSIFGGELPCPDNDLAHQPEDTVR---QK 69
Query: 79 LCPTITGNVCCTEEQLQAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDG 137
L ++ N+ E I+ CPAC NF N+FC +CSP+QSLF+N+T + G
Sbjct: 70 LIDALSSNLKLAEG------IIASCPACRDNFFNIFCTFTCSPDQSLFVNITKTEENSSG 123
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPG 197
V +D ++ + G + +CK+VK G +AIDF+G GA + + FLG K
Sbjct: 124 KRLVTELDNIWSKEYQSGFFDSCKNVKNGASGGKAIDFIGGGAKDDTHFMKFLGDK---K 180
Query: 198 FPGSPYSIDFKT--TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
F GSP+ I++ T + D+ ME ++ +CND
Sbjct: 181 FLGSPFQINYHTEPSGSDTQGMEALSIKPKACNDED------------------------ 216
Query: 256 XXXXIKMGSLKVRCVD------------------------LSLAVLYIVLVFVLFGWIXX 291
S + CVD LS AV+ + +F+LF
Sbjct: 217 -------KSFRCSCVDCPDVCPELPVISPHNICHVGLLPCLSFAVILVYSIFLLFVIALA 269
Query: 292 XXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAY 351
E + + + + ++ +GEV+ + + LS +
Sbjct: 270 SYVTYKERRFRKPERVRLLQDPTPSDDEDEGEVMHRGGYMERSQGVYKLNSVLSTLFHRI 329
Query: 352 GRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPF 411
G AR P I + SS+ V LL G L F+VET P +LWV P S AA+EK+FFD + PF
Sbjct: 330 GGTCARFPAITISSSVIGVALLSLGWLNFDVETDPVRLWVSPSSAAAQEKDFFDQNFGPF 389
Query: 412 YRIEQ-LIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKP 470
YR EQ ++ PE++ +P ++ + + F+++ +V + + L + +D+C KP
Sbjct: 390 YRAEQAFLVNNRPEND-SRP--LLDYETLTWWFDVESRVRRVISLDRAL--NFNDVCFKP 444
Query: 471 LGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF 530
GE C QS+ YF N D ++ +C + +C F PL+P LGGF
Sbjct: 445 TGEACVVQSVTGYFGGAVSNLDPDTWMDRLGHCTES-PGDPSCLPDFSQPLKPEMVLGGF 503
Query: 531 SGN-NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
N +A A I+T+ VNN + +E KAI WE F + +V
Sbjct: 504 EDTGNVLDAQALIVTWVVNN-YAQGTEEEAKAIDWENTFQAVLEV 547
>I1RY25_GIBZE (tr|I1RY25) Uncharacterized protein OS=Gibberella zeae (strain PH-1
/ ATCC MYA-4620 / FGSC 9075 / NRRL 31084) GN=FG09254.1
PE=4 SV=1
Length = 1273
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 165/547 (30%), Positives = 253/547 (46%), Gaps = 38/547 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P + L ++ LC TG VCCT +Q
Sbjct: 29 HEPGRCAFRGHCGKQSFFGKELPCVDNGLAEDPEEELRNELVGLCGEKWRTGPVCCTLDQ 88
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ +G CPAC NF NLFC +CSP+QS FINVT + +G V +D
Sbjct: 89 VKSLKSELGTPNTLIGSCPACKDNFFNLFCTFTCSPDQSTFINVTDSAPKNGKNLVTELD 148
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+E +G G Y +CK+VKFG N+RA+D +G GA NY E FLG K P F GSP+ I
Sbjct: 149 HLVSEKYGSGFYDSCKEVKFGGANSRAMDLIGGGAKNYTEMLTFLGNKKP--FAGSPFQI 206
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T ++ ++ CND K+G L
Sbjct: 207 NFPTQ-QKVPKLQPVDMKPKKCNDED---PNYRCVCVDCPEVCAKLPEVKDSKSCKVGLL 262
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + +Y VL+ L + L+ E S ++ +G +
Sbjct: 263 P--CLSFASIFVYGVLLSTLILAVTGHIAYQKYSQHRVERTRLLHES-SHSDDEDEGGPV 319
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R+ + ++ + + G AAR P + SL V +L GL RF++E
Sbjct: 320 DTEAMRERPTKRYWVNDRCDRGFYQLGHIAARFPGWCIGLSLLFVGILSIGLFRFDLEKE 379
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FD + PFYR E++ +A ++ P +++ D ++ E+
Sbjct: 380 PARLWVSPSSAAAQEKAYFDENFGPFYRAEKIFLAN--DTNPSGPGPVLSYDTLKWWIEV 437
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQ----MDPDNFDNYGGVEHAE 501
+E V +I + G D+C KP + C QS+ Y+ +DP + +
Sbjct: 438 EESVKKIESPVYGKY--FQDLCFKPSNDACVVQSVSAYWHSKGGLDPQTWK-----DDIR 490
Query: 502 YCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKA 561
C + S C F P+EP GG+ G++ +A A +T+ VNNA + D +A
Sbjct: 491 ACAK---SPVDCRPDFGQPIEPNMIFGGY-GDDIVDAHAITVTWVVNNA-KEGTDAIARA 545
Query: 562 IAWEKAF 568
+ WE A
Sbjct: 546 VDWETAL 552
>Q0CK25_ASPTN (tr|Q0CK25) Putative uncharacterized protein OS=Aspergillus terreus
(strain NIH 2624 / FGSC A1156) GN=ATEG_05959 PE=4 SV=1
Length = 1263
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 166/554 (29%), Positives = 256/554 (46%), Gaps = 36/554 (6%)
Query: 28 TAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN 86
T AQ +H CA+ CG++S G L CP + P + K+ LC T +
Sbjct: 18 TLAQGETKVHEKGRCAIRGHCGKKSFFGGELPCPDNGRAADPEPAVRKKLVDLCGTKWED 77
Query: 87 --VCCTEEQLQ-AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDG 143
+ + L+ A I+ CPAC NF N FC +CSP+QSLF+NVT + G V
Sbjct: 78 SPIDALAKNLKLAEGIIASCPACKENFFNTFCTFTCSPDQSLFVNVTQTDEARGKTLVTE 137
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
ID +E + G Y +CK+VK G +A+DF+G GA NY ++ FLG K GSP+
Sbjct: 138 IDNIWSEEYQSGFYDSCKNVKNGASGGKAMDFIGGGAKNYTQFMKFLGDK---KLLGSPF 194
Query: 204 SIDFKTTILDSSPMELMNASV--YSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIK 261
I++KT + P +M + +CND+
Sbjct: 195 QINYKTEPVGPDPQGMMPLPITPKACNDSD---EAFRCSCVDCPDVCPELAPVQADKHCH 251
Query: 262 MGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKD 321
+G L LS +V+ I +F+LF E + + + + ++ +D
Sbjct: 252 VGLLPC----LSFSVILIYSIFLLFVAGLSSFFTYRERRYRKPERVRLLQDPAPSDDEED 307
Query: 322 GEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFN 381
GE++ + + L + + AR P + + SS+ +V LL G LRF
Sbjct: 308 GEIVHSAGYLETPTSIYKLNSALESLFNRIAGACARFPAVTITSSVLVVALLSLGWLRFA 367
Query: 382 VETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQ-LIIATLPESEHGKPPSIVTDDNIE 440
VET P +LWV P S AA EKE+FD + PFYR EQ ++ + HG+ +++ + +
Sbjct: 368 VETDPVRLWVSPTSAAALEKEYFDQNFGPFYRAEQAFLVNDTSDGAHGR---VLSYETLS 424
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYF-----QMDPDNFDNYG 495
F+++ +V + + GL+ L D+C KP G+ C QS+ YF ++PD +
Sbjct: 425 WWFDVESRVRRMISLDRGLI--LDDVCFKPTGDACVVQSLTGYFGGSVMNLNPDTWQ--- 479
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN-ALTKV 554
+ +C + +C F PL P LGG+ N ++ A I T+ VNN A
Sbjct: 480 --DRLVHCTES-PGDVSCLPDFGQPLRPEMILGGYGSGNVLDSKALIATWVVNNYAQGTE 536
Query: 555 GDENGKAIAWEKAF 568
G+ N AI WE +F
Sbjct: 537 GEAN--AIDWEVSF 548
>N4XGI6_COCHE (tr|N4XGI6) Uncharacterized protein OS=Bipolaris maydis ATCC 48331
GN=COCC4DRAFT_137183 PE=4 SV=1
Length = 1271
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 158/548 (28%), Positives = 245/548 (44%), Gaps = 32/548 (5%)
Query: 15 LQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLS 73
+ V +LS + S A + H CAM CG++ G L CP + P D +
Sbjct: 12 MTVGLLSILAGSALAGPDLTTRHEKGRCAMRGQCGKQGFFGSELPCPDNGLAKTPDDDVR 71
Query: 74 AKIQSLCPT--ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQ 123
K+ +C T ++CC E+QL +A PI+ CPAC NF NLFC +CSP+Q
Sbjct: 72 KKLVDICGTQWSDSDICCDEDQLDALKTNLDRATPIINACPACKENFYNLFCTFTCSPDQ 131
Query: 124 SLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNY 183
S F+N+T V +D + + + Y +CKDVKFG N +A+DF+G GA N+
Sbjct: 132 STFVNITGTEPKSDKYLVTELDNLIADKYASTFYDSCKDVKFGATNGKAMDFIGGGAKNF 191
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXX 242
++ FLG K F GSP+ I+F + P M M+ Y C+
Sbjct: 192 TQFLKFLGDK---KFLGSPFQINFPRPSQELFPGMTAMSKRAYPCDTED---EKYRCACL 245
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXG 301
+G L LS AV+ I F+ L
Sbjct: 246 DCGTSCTELPAVQEGEQCHVGLLPC----LSFAVIIIYSCFIGLLCIAVAGHVAYQKHSR 301
Query: 302 SSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTI 361
E + + + S ++ +G+++ ++ F+ W + G AR P I
Sbjct: 302 HKTERMRLLQDTSPSDDEDEGDIVHNVGMLDRPTKHYFVNTWCDRMFSRLGYICARFPAI 361
Query: 362 VLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT 421
+ +S+ +V L+ G L+F +ET P LWV P+S AA+EK FFD PF+R EQ A
Sbjct: 362 TIITSVIVVALMSLGWLQFKIETDPVNLWVSPDSAAAQEKAFFDEKFGPFFRAEQ---AF 418
Query: 422 LPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSIL 481
L P +++ + ++ F ++ ++ +++ G V+L IC KP+G+DC QS+
Sbjct: 419 LVNDTLDSPGPVLSYETLDWWFGVENQIQRLKSAEHG--VTLDQICFKPVGDDCVVQSVT 476
Query: 482 QYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
YFQ D F N + Q + C F+ PL+ GG + +A A
Sbjct: 477 GYFQGD---FANVVPSSWKDDLLQCVDNPSQCLPTFQQPLDSHLLFGGVE-ESVLDAKAL 532
Query: 542 IITYPVNN 549
++T+ V N
Sbjct: 533 VVTWVVQN 540
>M2UL16_COCHE (tr|M2UL16) Uncharacterized protein OS=Bipolaris maydis C5
GN=COCHEDRAFT_1226803 PE=4 SV=1
Length = 1271
Score = 233 bits (593), Expect = 2e-58, Method: Compositional matrix adjust.
Identities = 158/548 (28%), Positives = 245/548 (44%), Gaps = 32/548 (5%)
Query: 15 LQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLS 73
+ V +LS + S A + H CAM CG++ G L CP + P D +
Sbjct: 12 MTVGLLSILAGSALAGPDLTTRHEKGRCAMRGQCGKQGFFGSELPCPDNGLAKTPDDDVR 71
Query: 74 AKIQSLCPT--ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQ 123
K+ +C T ++CC E+QL +A PI+ CPAC NF NLFC +CSP+Q
Sbjct: 72 KKLVDICGTQWSDSDICCDEDQLDALKTNLDRATPIINACPACKENFYNLFCTFTCSPDQ 131
Query: 124 SLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNY 183
S F+N+T V +D + + + Y +CKDVKFG N +A+DF+G GA N+
Sbjct: 132 STFVNITGTEPKSDKYLVTELDNLIADKYASTFYDSCKDVKFGATNGKAMDFIGGGAKNF 191
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXX 242
++ FLG K F GSP+ I+F + P M M+ Y C+
Sbjct: 192 TQFLKFLGDK---KFLGSPFQINFPRPSQELFPGMTAMSKRAYPCDTED---EKYRCACL 245
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXG 301
+G L LS AV+ I F+ L
Sbjct: 246 DCGTSCTELPAVQEGEQCHVGLLPC----LSFAVIIIYSCFIGLLCIAVAGHVAYQKHSR 301
Query: 302 SSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTI 361
E + + + S ++ +G+++ ++ F+ W + G AR P I
Sbjct: 302 HKTERMRLLQDTSPSDDEDEGDIVHNVGMLDRPTKHYFVNTWCDRMFSRLGYICARFPAI 361
Query: 362 VLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT 421
+ +S+ +V L+ G L+F +ET P LWV P+S AA+EK FFD PF+R EQ A
Sbjct: 362 TIITSVIVVALMSLGWLQFKIETDPVNLWVSPDSAAAQEKAFFDEKFGPFFRAEQ---AF 418
Query: 422 LPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSIL 481
L P +++ + ++ F ++ ++ +++ G V+L IC KP+G+DC QS+
Sbjct: 419 LVNDTLDSPGPVLSYETLDWWFGVENQIQRLKSAEHG--VTLDQICFKPVGDDCVVQSVT 476
Query: 482 QYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
YFQ D F N + Q + C F+ PL+ GG + +A A
Sbjct: 477 GYFQGD---FANVVPSSWKDDLLQCVDNPSQCLPTFQQPLDSHLLFGGVE-ESVLDAKAL 532
Query: 542 IITYPVNN 549
++T+ V N
Sbjct: 533 VVTWVVQN 540
>F0X9U6_GROCL (tr|F0X9U6) Patched sphingolipid transporter OS=Grosmannia
clavigera (strain kw1407 / UAMH 11150) GN=CMQ_3403 PE=4
SV=1
Length = 1295
Score = 232 bits (591), Expect = 4e-58, Method: Compositional matrix adjust.
Identities = 171/560 (30%), Positives = 258/560 (46%), Gaps = 51/560 (9%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA+ CG++S L C + +P L ++ LC TG +CCT+ Q
Sbjct: 36 HEAGRCAIRGQCGKQSLFSPELPCVDNGLAEEPDAALRQQLVGLCGAKWSTGPICCTDVQ 95
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
+ A+ ++ CPAC NF NLFC +CSP+QSLFINVT+ ++ + + V +D
Sbjct: 96 VAALKDNLGTVNQLISSCPACKDNFYNLFCTFTCSPDQSLFINVTNAAKKNDKVLVTELD 155
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+E +G G Y +CK+VKFG N++A+D +G GA +Y E AFLG+K GSP+ +
Sbjct: 156 QLVSEEYGTGFYDSCKEVKFGPTNSKAMDLIGGGAKDYHELLAFLGKK---RLGGSPFQM 212
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F + M+ + CND +G L
Sbjct: 213 NFPAE-YEEPEMKPRQMTPKKCNDED---PSFRCACTDCPSVCPALPEVKNASSCHVGLL 268
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL--------------VSE 311
C+ S ++Y V V VL WI G+ A PLL +
Sbjct: 269 P--CLSFSSILVYSVFVAVLLAWI--ALRFWYTNGGTKALPLLHDPRSGHDEDDDVEDDD 324
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
R+F G + Y + + +R G WAAR P + +SL +
Sbjct: 325 RRAFLYQIIHGSGTTGADIEEPPQSYK-LNTMCNAVFRRLGHWAARFPGTSIGASLLVAT 383
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA--TLPESEHGK 429
+L G LRF +E PEKLWV P S AA+EK FFD++ PFYR E++ + TLP
Sbjct: 384 VLSLGWLRFELELVPEKLWVSPSSAAAQEKAFFDTNFGPFYRAEKIFLVNDTLPTG---- 439
Query: 430 PPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPD 489
P +++ D + +++ +++I+ + G+ + D+C KP G+ C QS+ YF D
Sbjct: 440 PGPVLSYDALFWWMNVEKSIEKIKGSEFGM--TFDDVCFKPTGKACVLQSVSAYFGSDTA 497
Query: 490 NFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSG-NNYSEASAFIITYPVN 548
D Y E C + S C + PL+P GGFS + ++A A +T+ VN
Sbjct: 498 LLDKYWK-ETLTACAK---SPVECRPEYGQPLDPEAIFGGFSDVEHVADAPAITVTWVVN 553
Query: 549 NALTKVGDENGKAIAWEKAF 568
N + E A+ WE+A
Sbjct: 554 N-YEEGTPEVKLAMDWERAL 572
>H1VM94_COLHI (tr|H1VM94) Patched sphingolipid transporter OS=Colletotrichum
higginsianum (strain IMI 349063) GN=CH063_02575 PE=4
SV=1
Length = 1247
Score = 231 bits (590), Expect = 5e-58, Method: Compositional matrix adjust.
Identities = 164/549 (29%), Positives = 253/549 (46%), Gaps = 42/549 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG +S GK L CP + +P + L +I LC +G VCC +Q
Sbjct: 30 HEAGRCAMRGHCGSKSFFGKQLPCPDNGLAEEPDEKLRQQIVDLCGAKWNSGPVCCDADQ 89
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+N+T + + V +D
Sbjct: 90 VKSLASELGTPNQIISSCPACKENFFNLFCTFTCSPDQSLFLNITKTQEKNKKTMVTELD 149
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+++ +G G + +CK+VKFG N+RAIDF+G GA NY + FLG + GSP+ I
Sbjct: 150 QLISKDYGTGFFDSCKEVKFGPSNSRAIDFIGGGAKNYTQLLKFLGDE---KVIGSPFQI 206
Query: 206 DFKTTILDS--SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
+F + SP +L + CND K G
Sbjct: 207 NFPAEYNEPGMSPRDLKSK---KCNDEDPNYRCACVDCPSVCPELPAVS--------KPG 255
Query: 264 SLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
V C+ + Y +L+FV + S L+ + S ++
Sbjct: 256 ECHVGLLPCLSFAAIFTYSILLFVAIAGVVGHVVWRRRARRESERLRLLQDA-SPSDDED 314
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
+G+++ ++ I W + G AAR I + +L +VI+L G +RF
Sbjct: 315 EGDLVQNGAMFDRPQRFYKINTWCDAAFSKLGHAAARYQGITIGVTLIVVIILSAGWVRF 374
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS-IVTDDNI 439
++E P +LWV P S AA+EK FFD PFYR E++ + +H K P+ +++ D +
Sbjct: 375 DLERDPARLWVSPASPAAKEKAFFDEQFGPFYRAEKMFLVN---DQHSKEPAPVLSYDTL 431
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
++++ V +++ G +L DICLKP G C QS+ YF DP +
Sbjct: 432 LWWMDVEKSVLQLKGPEFG--ATLDDICLKPTGNACVVQSVAAYFGNDPSLVGKNDWKDQ 489
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
C + S C F PLEP LGG+ ++ A+A +T+ V NA +
Sbjct: 490 LRQCAK---SPVECRPEFGLPLEPNMILGGWK-DDPVNATAITVTWVVQNA-AEGSPAVE 544
Query: 560 KAIAWEKAF 568
+A+ WE A
Sbjct: 545 RAMDWEIAL 553
>A1CTG5_ASPCL (tr|A1CTG5) Patched sphingolipid transporter (Ncr1), putative
OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 /
DSM 816 / NCTC 3887 / NRRL 1) GN=ACLA_082940 PE=4 SV=1
Length = 1274
Score = 231 bits (589), Expect = 6e-58, Method: Compositional matrix adjust.
Identities = 171/568 (30%), Positives = 256/568 (45%), Gaps = 36/568 (6%)
Query: 19 ILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQ 77
+LS S Q IH CA+ CG++S G L CP + +P K+
Sbjct: 15 LLSSLPQSFVLGQGETKIHEEGRCAIRGHCGKKSFFGGELPCPDNDIAREPEVSARKKLV 74
Query: 78 SLCPTI--TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFI 127
+LC + G VCC EEQ+ A+ I+ CPAC NF N+FC +CSP+QSLFI
Sbjct: 75 NLCGSKWEEGPVCCEEEQIDALAKNLKLAEGIIASCPACKDNFFNIFCTFTCSPDQSLFI 134
Query: 128 NVTSISQ-VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEW 186
NVT + G V +D +E + G Y +CK+VK G +AIDF+G GA NY ++
Sbjct: 135 NVTKTEKGSSGKPLVTELDNIWSEEYQSGFYDSCKNVKNGASGGKAIDFIGGGAKNYTQF 194
Query: 187 FAFLGQKVPPGFPGSPYSIDFKT--TILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXX 244
FLG K GSP+ I+++T T D M ++ + +CND
Sbjct: 195 LKFLGDK---KLLGSPFQINYRTEPTGPDDQGMRPLSITPKACNDAD---EAFRCSCVDC 248
Query: 245 XXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSA 304
+G L +S AV+ I +F+L
Sbjct: 249 PEVCPQLPEVKTDKDCHVGLLPC----MSFAVILIYSLFILAIISFSSYFTYRERRYRKP 304
Query: 305 EPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLC 364
E + + + S ++ +G+++ + + L + G + AR P I +
Sbjct: 305 ERVRLLQDPSPSDDEDEGDIVHAGGLLEQPTGVYKLNSMLDAMFNRIGGFCARFPAITIF 364
Query: 365 SSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPE 424
+S+ V LL G LRF VET P +LWV P S AA+EKE+FD++ PFYR EQ +
Sbjct: 365 TSILFVGLLSLGWLRFAVETDPVRLWVSPTSAAAQEKEYFDTNFGPFYRAEQAFLV---- 420
Query: 425 SEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYF 484
++HG +++ D + ++ ++ + ++ GLL L +C KP G+ C QSI YF
Sbjct: 421 NDHGP---VLSYDTLTWWSGVESRIRRVNSSDHGLL--LDQVCFKPTGDACVIQSITGYF 475
Query: 485 QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFII 543
N E ++C + +C F PL P LGG+ N +A A I
Sbjct: 476 GGSASNIQPDTWEERVKHC-ANSPGDPSCLPDFSQPLRPEMILGGYEETGNVLDAKALIT 534
Query: 544 TYPVNNALTKVGDENGKAIAWEKAFIQL 571
T+ VNN + + A+ WE F L
Sbjct: 535 TWVVNN-FEQRSEGEAYAVDWELTFKSL 561
>M2NKG5_9PEZI (tr|M2NKG5) Uncharacterized protein OS=Baudoinia compniacensis UAMH
10762 GN=BAUCODRAFT_62794 PE=4 SV=1
Length = 1290
Score = 231 bits (588), Expect = 8e-58, Method: Compositional matrix adjust.
Identities = 162/551 (29%), Positives = 248/551 (45%), Gaps = 37/551 (6%)
Query: 35 SIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTE 91
+IH CA+ CG +S G L CP + +P L +I S+C VCC E
Sbjct: 31 TIHEAGRCAIRGHCGSQSLFGSQLPCPDNDLAEEPSVELRQQIISVCGDAWTDTKVCCRE 90
Query: 92 EQLQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDG 143
EQ++ A I+ CPAC +NF +LFC +CSP+QSLF+NVT +G V
Sbjct: 91 EQVETLQSNLQKAQNIISACPACKKNFFDLFCTFTCSPDQSLFVNVTKTVPKNGKFLVTE 150
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+D +++ +G G Y +CKDVKFG +A++F+G GA NY + FLG K P F GSP+
Sbjct: 151 LDHLISDEYGSGFYDSCKDVKFGATGGKAMEFIGGGARNYTRFLKFLGDKKP--FLGSPF 208
Query: 204 SIDF-KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
IDF + + D ME + CN T +
Sbjct: 209 QIDFPRPSSEDFGDMETILDDPKPCNSTD---ERYRCACVDCAGSCPELPKVEQAEQCTV 265
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
G L C+ + ++Y V + +L + + L+ + +
Sbjct: 266 GLLP--CLSFGVLLVYSVFITLLVLAVTGHAAAAKRRKSKNERLQLLHDTTADEEDDARD 323
Query: 323 EVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNV 382
+ + Q + + + + R AR P I + SS+ +V LL G +RF +
Sbjct: 324 AIHMASFQGDKPTKQYVLNTYCDRAFSRLARTCARFPAITIVSSIIVVGLLSLGWIRFAI 383
Query: 383 ETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELL 442
ET P LWV P S AA+EK FFD++ PF+R EQ + +++ P +++ + +
Sbjct: 384 ETDPVGLWVAPNSDAAQEKHFFDTNFGPFFRAEQAFLVN--DTQPSGPGPVLSYETLRWW 441
Query: 443 FEIQEKVDEIRA---NYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEH 499
F+++ +V ++ NY +L D+C KP GE C QS+ QYF D +
Sbjct: 442 FDVERRVAAQKSLVHNY-----TLQDVCYKPTGEACVIQSVTQYFGGSFDQLEEDDWAAQ 496
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGG--FSGNNYSEASAFIITYPVNNALTKVGDE 557
+ C + C F PL LGG +S ++A A I T+ V N GD
Sbjct: 497 IQDCVD---TPVNCLPDFGQPLAIQRLLGGYNYSSQPITDAEALITTWVVKN--HNPGDP 551
Query: 558 N-GKAIAWEKA 567
+ KA WE++
Sbjct: 552 DLAKAEEWEES 562
>E3QUA2_COLGM (tr|E3QUA2) Patched sphingolipid transporter OS=Colletotrichum
graminicola (strain M1.001 / M2 / FGSC 10212)
GN=GLRG_09584 PE=4 SV=1
Length = 1276
Score = 230 bits (587), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 166/545 (30%), Positives = 249/545 (45%), Gaps = 34/545 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CAM CG +S GK L CP + +P + L +I LC +G VCC EQ
Sbjct: 30 HEAGRCAMRGHCGSKSFFGKQLPCPDNGLAEEPDEKLRQEIVDLCGEKWKSGPVCCDAEQ 89
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+N+T + + V +D
Sbjct: 90 VKSLASELGTPKQIISSCPACKENFFNLFCTFTCSPDQSLFLNITKTQEKNKKTMVTELD 149
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+++ +G G + +CK+VKFG N+RAIDF+G GA NY + FLG + GSP+ I
Sbjct: 150 QLISKDYGTGFFDSCKEVKFGPSNSRAIDFIGGGAKNYTQLLKFLGDE---KVIGSPFQI 206
Query: 206 DFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGS 264
+F T S P M + CND +G
Sbjct: 207 NFPTEY--SEPGMAPRDLKSKRCNDED---PNYRCACVDCPSVCPELPAVSRPGECHVGV 261
Query: 265 LKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEV 324
L C+ + Y VL+F + S L+ + S ++ +G++
Sbjct: 262 LP--CLSFAAIFTYSVLLFAAVAGVIGHIAWRRRARRESERLRLLQDA-SPSDDEDEGDL 318
Query: 325 LVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVET 384
+ +Y I W + G AAR I + +L VI+L G +RF++E
Sbjct: 319 VQNGAMFDRPQRYYKINTWCDAAFSKLGHAAARYQGITIGVTLIFVIILSAGWVRFDLER 378
Query: 385 RPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS-IVTDDNIELLF 443
P +LWV P S AA+EK FFD PFYR E+ A L +H K P+ +++ D +
Sbjct: 379 DPARLWVSPTSAAAQEKAFFDDQFGPFYRAEK---AFLVNDQHSKEPAPVLSYDTLLWWM 435
Query: 444 EIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYC 503
++++ V ++++ G +L DICLKP G C QS+ Y+ +P C
Sbjct: 436 DVEKSVKQLKSAKFG--ATLDDICLKPTGNACVVQSVAAYYGDEPSLVGKNDWQNQLRQC 493
Query: 504 FQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
+ S C F P+EP LGG+ ++ A+A +T+ V NA + AI
Sbjct: 494 AK---SPVECRPEFGLPIEPNMILGGYK-DDPVNATAMTVTWVVKNA-AEGSPAVEHAID 548
Query: 564 WEKAF 568
WE A
Sbjct: 549 WEIAL 553
>N4VGD5_COLOR (tr|N4VGD5) Patched sphingolipid transporter OS=Colletotrichum
orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 /
LARS 414 / MAFF 240422) GN=Cob_01149 PE=4 SV=1
Length = 1271
Score = 230 bits (586), Expect = 1e-57, Method: Compositional matrix adjust.
Identities = 164/548 (29%), Positives = 252/548 (45%), Gaps = 40/548 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA+ CG +S GK L C + P + L +I LC +G VCC +Q
Sbjct: 25 HEAGRCAIRGHCGSKSFFGKQLPCVDNGLAEDPDEKLRQQIVDLCGEKWNSGPVCCDADQ 84
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
++++ I+ CPAC NF NLFC +CSP+QSLF+NVT + + V +D
Sbjct: 85 VKSLSSELGTPNQIISSCPACKDNFFNLFCTFTCSPDQSLFLNVTKTMEKNKKEMVTELD 144
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+++ +G G + +CK+VKFG N++AIDF+G GA NY + FLG + GSP+ I
Sbjct: 145 QLISKEYGTGFFDSCKEVKFGPSNSKAIDFIGGGAKNYSQLLKFLGDE---KVIGSPFQI 201
Query: 206 DF--KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
+F + T D +P +L + CND K G
Sbjct: 202 NFPAEYTEPDMAPKDL---TPKKCNDEDPNYRCACVDCPSVCPELPAVS--------KPG 250
Query: 264 SLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
V C+ + Y +L+F + S E L + + S ++
Sbjct: 251 ECHVGLLPCLSFAAIFTYSILLFSAIAAVVGHIIWRRRAKRES-ERLRLLQDASPSDDED 309
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
+G+++ +Y I W + G AAR I + +L +VI+L G +RF
Sbjct: 310 EGDLVQNGAMFDRPQRYYKINTWCDAAFSKLGHAAARYQGITIGVTLIVVIILSAGWVRF 369
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIE 440
++E P +LWV P S AA EK FFD PFYR E++ + + + G P +++ D I
Sbjct: 370 DIERDPARLWVSPTSAAAREKAFFDEQFGPFYRAEKMFLVN--DQQPGGPAPVLSYDTIL 427
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHA 500
E+++ V +++ G +L DICLKP G C QS YF +P +
Sbjct: 428 WWMEVEKSVKQLKGPKYG--ATLDDICLKPTGTSCVVQSFATYFDNEPSLVGRDDWQDQL 485
Query: 501 EYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK 560
C + S C F P+EPT LGG+ + + A+A +T+ V+NA + +
Sbjct: 486 RQCAK---SPVECRPDFGLPIEPTMILGGYDEDPVN-ATAITVTWVVSNA-AEGSPAVER 540
Query: 561 AIAWEKAF 568
A+ WE A
Sbjct: 541 AMDWEVAL 548
>B8NIY3_ASPFN (tr|B8NIY3) Patched sphingolipid transporter (Ncr1), putative
OS=Aspergillus flavus (strain ATCC 200026 / FGSC A1120 /
NRRL 3357 / JCM 12722 / SRRC 167) GN=AFLA_070110 PE=4
SV=1
Length = 1147
Score = 229 bits (584), Expect = 2e-57, Method: Compositional matrix adjust.
Identities = 171/556 (30%), Positives = 255/556 (45%), Gaps = 40/556 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ ++H CA+ CG++S G L CP + +P + K+ LC + G
Sbjct: 23 AQGETALHEKGRCAIRGHCGKKSFFGGELPCPDNGLAEEPETAVRKKLVDLCGSKWEEGP 82
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS-QVDG 137
VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLF+NVT G
Sbjct: 83 VCCKDEQIDALSKNLKLAEGIIASCPACKENFFNIFCTFTCSPDQSLFLNVTETEPSSSG 142
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPG 197
V +D +E + G Y +CK+VK G +A+DF+G GA +Y + FLG K
Sbjct: 143 KSLVTELDNIWSEEYQSGFYESCKNVKNGASGGKAMDFIGGGAKDYTHFLKFLGDK---K 199
Query: 198 FPGSPYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
GSP+ I+FKT P M + +CND+
Sbjct: 200 LLGSPFQINFKTEPAGPDPQGMHPLPIKPKACNDSD---EAFRCSCVDCPDVCPQLPAVE 256
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
+G L LS AV+ I VF+LF E + + + +
Sbjct: 257 TDKQCHVGLLPC----LSFAVILIYSVFLLFVVALSSYFTYKERRHRKPERVRLLQDPTP 312
Query: 316 TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
++ +G+++ + + L + + G AR P + + SS+ V LL
Sbjct: 313 SDDEDEGDIVHAGGYLEQPKGVYKLNSVLDSVFSHIGGTCARFPAVTIVSSIIAVGLLSL 372
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
G LRF VET P +LWV P S A +EK++FD++ PFYR EQ + ++ G ++T
Sbjct: 373 GWLRFAVETDPVRLWVSPTSAAFQEKQYFDANFGPFYRAEQAFLV----NDSGP---VLT 425
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
D + F+++ +V + + G++ L DIC KP G+ C QS+ YF N D
Sbjct: 426 YDTLSWWFDVESRVRRMISLDRGII--LDDICFKPTGDACVVQSVTGYFGGSMYNLDPDT 483
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF--SGNNYSEASAFIITYPVNNALTK 553
E +C + C F PL+P LGG+ SG+ + +A A I T+ VNN
Sbjct: 484 WKERVRHCAESPGDV-NCLPEFGQPLKPEMILGGYEESGDVF-DARALIATWVVNNHAQ- 540
Query: 554 VGDEN-GKAIAWEKAF 568
G EN AI WE +F
Sbjct: 541 -GTENEANAIDWEDSF 555
>I8IGC5_ASPO3 (tr|I8IGC5) Cholesterol transport protein OS=Aspergillus oryzae
(strain 3.042) GN=Ao3042_06561 PE=4 SV=1
Length = 1270
Score = 229 bits (584), Expect = 3e-57, Method: Compositional matrix adjust.
Identities = 171/556 (30%), Positives = 255/556 (45%), Gaps = 40/556 (7%)
Query: 30 AQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGN 86
AQ ++H CA+ CG++S G L CP + +P + K+ LC + G
Sbjct: 23 AQGETALHEKGRCAIRGHCGKKSFFGGELPCPDNGLAEEPETAVRKKLVDLCGSKWEEGP 82
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS-QVDG 137
VCC +EQ+ A+ I+ CPAC NF N+FC +CSP+QSLF+NVT G
Sbjct: 83 VCCKDEQIDALSKNLKLAEGIIASCPACKENFFNIFCTFTCSPDQSLFLNVTETEPSSSG 142
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPG 197
V +D +E + G Y +CK+VK G +A+DF+G GA +Y + FLG K
Sbjct: 143 KSLVTELDNIWSEEYQSGFYESCKNVKNGASGGKAMDFIGGGAKDYTHFLKFLGDK---K 199
Query: 198 FPGSPYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
GSP+ I+FKT P M + +CND+
Sbjct: 200 LLGSPFQINFKTEPAGPDPQGMHPLPIKPKACNDSD---EAFRCSCVDCPDVCPQLPAVE 256
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
+G L LS AV+ I VF+LF E + + + +
Sbjct: 257 TDKQCHVGLLPC----LSFAVILIYSVFLLFVVALSSYFTYKERRHRKPERVRLLQDPTP 312
Query: 316 TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
++ +G+++ + + L + + G AR P + + SS+ V LL
Sbjct: 313 SDDEDEGDIVHAGGYLEQPKGVYKLNSVLDSVFSHIGGTCARFPAVTIVSSIIAVGLLSL 372
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
G LRF VET P +LWV P S A +EK++FD++ PFYR EQ + ++ G ++T
Sbjct: 373 GWLRFAVETDPVRLWVSPTSAAFQEKQYFDANFGPFYRAEQAFLV----NDSGP---VLT 425
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
D + F+++ +V + + G++ L DIC KP G+ C QS+ YF N D
Sbjct: 426 YDTLSWWFDVESRVRRMISLDRGII--LDDICFKPTGDACVVQSVTGYFGGSMYNLDPDT 483
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF--SGNNYSEASAFIITYPVNNALTK 553
E +C + C F PL+P LGG+ SG+ + +A A I T+ VNN
Sbjct: 484 WKERVRHCAESPGDV-NCLPEFGQPLKPEMILGGYEESGDVF-DARALIATWVVNNHAQ- 540
Query: 554 VGDEN-GKAIAWEKAF 568
G EN AI WE +F
Sbjct: 541 -GTENEANAIDWEDSF 555
>C5MCB4_CANTT (tr|C5MCB4) Putative uncharacterized protein OS=Candida tropicalis
(strain ATCC MYA-3404 / T1) GN=CTRG_03706 PE=4 SV=1
Length = 1259
Score = 228 bits (582), Expect = 4e-57, Method: Compositional matrix adjust.
Identities = 167/584 (28%), Positives = 271/584 (46%), Gaps = 64/584 (10%)
Query: 14 LLQVLILSWFSPSLTAAQISRSI-HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDL 71
+LQ+L+L+ LT + + S+ H YC YD CG++S GK L C P+VK
Sbjct: 3 ILQLLVLA---VHLTISIATSSLQHKPGYCNTYDNCGKKSVFGKPLPCSTFQPAVKASKE 59
Query: 72 LSAKIQSLCPTITGNVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQ 123
K++++C +CC+ EQ+ ++ P++ CPAC +NF + FC SCSPN+
Sbjct: 60 SMDKLKAICGEEFEYICCSPEQIDSLESNLKRVDPLISSCPACRKNFYDFFCRFSCSPNE 119
Query: 124 SLFINV--TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGAN 181
S F+ + T I++ G V I+ YV + Y +CK+VKF N A+D +G GA
Sbjct: 120 SQFVEILKTDIAKDTGKEIVTEINQYVNPDMAKKFYDSCKNVKFSATNGFAMDLIGGGAK 179
Query: 182 NYKEWFAFLGQKVPPGFPGSPYSIDFKTTI---LDSSPMELMNASVYSCNDTSLGXXXXX 238
NY ++ FLG + P GSPY I+FK + + + L N V SC+D
Sbjct: 180 NYSQFLKFLGDE-KPLLGGSPYQINFKYELSKEQEQAGFVLRNEDVKSCDDEVFKCACTD 238
Query: 239 XXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFG---WIXXXXXX 295
+ + C ++ + + L+ +L G ++
Sbjct: 239 CEESCPKLPHARDLNKKCTVGV------LPCFSFTIIIFWSCLILMLGGYHVYLAKLKRA 292
Query: 296 XXXXXGSSAEPLLVSE-------GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFY 348
AE + GR + + Q + + F+ + +NF
Sbjct: 293 RGRRISIGAEDDDDDDIDTMMDPGRYVNFTKRSAKAFSHRLSTQIQDAFEFVGSFCANF- 351
Query: 349 RAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHL 408
P I + SLAI ILL FGL + +ET P KLWV PE ++ + +++F+++
Sbjct: 352 ----------PGISIGGSLAIAILLSFGLFKLQLETDPVKLWVSPEDQSYKNQQYFENNF 401
Query: 409 APFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICL 468
++R+EQ+I++ S+ P ++ D + FE + +++++ N VSLSDIC
Sbjct: 402 GEWFRVEQVIVS----SKTDNP--VLNWDVFKWWFEKESQLEDLNKN-----VSLSDICF 450
Query: 469 KPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALG 528
KPLG CA QS QYFQ D D + C S C F+ PL+P
Sbjct: 451 KPLGNTCAIQSFTQYFQGDITGLDENNWRAKLQNCVN---SPVNCLPTFQQPLKPNIL-- 505
Query: 529 GFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLA 572
F N+ S+A AF +T VN+ +K + + +++E +F++ A
Sbjct: 506 -FDNNDISKAKAFTVTVLVNSD-SKDKKYSAETVSYEHSFLEWA 547
>N1QMD0_9PEZI (tr|N1QMD0) Multidrug efflux transporter AcrB transmembrane
domain-containing protein OS=Mycosphaerella populorum
SO2202 GN=SEPMUDRAFT_145776 PE=4 SV=1
Length = 1285
Score = 228 bits (582), Expect = 4e-57, Method: Compositional matrix adjust.
Identities = 164/559 (29%), Positives = 260/559 (46%), Gaps = 55/559 (9%)
Query: 35 SIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTE 91
S H CA+ CG++S GK L CP + P D + AK+ S+C G VCC +
Sbjct: 35 SRHEAGRCAIRGQCGKQSLFGKELPCPDNGLAEDPTDEVRAKLVSICGDEWSDGKVCCQD 94
Query: 92 EQLQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDG 143
+QL A I+ C AC +NF +LFC +CSP+QSLF+NVTSI V
Sbjct: 95 DQLDVLKSNLDTANSIISSCGACKKNFFDLFCTFTCSPDQSLFVNVTSIVPKGDKFLVTE 154
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+D V E +G G Y +C DVKFG RA+DF+G GA NY + FLG K P F GSP+
Sbjct: 155 LDHLVAEDYGTGFYDSCSDVKFGATGGRAMDFIGGGAKNYTQMLKFLGDKKP--FVGSPF 212
Query: 204 SIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
I+F + M+ + CN T +G
Sbjct: 213 QINFPPPSENFPGMQPILHESTPCNTTD---ERYRCACVDCAGACPALPQVHQTELCHVG 269
Query: 264 SLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGE 323
L C+ ++ ++Y + V +L + S E L + + S ++ +G+
Sbjct: 270 LLP--CLSFAVVLIYSIFVALLVLAVSGHAAAAKRRR-SKNERLQLLQDASPSDDEDEGD 326
Query: 324 VL----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLR 379
++ ++D + V +F SN GR A+ P I + + + +V LLC G +R
Sbjct: 327 MVHGVGMLDRPTKQYVVNTFCDRIFSNL----GRTCAKFPAITISTCVIVVALLCIGWVR 382
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
F++ET P LWV P S AA EK FFD + PF+R EQ + ++ P +++ + +
Sbjct: 383 FDIETDPVNLWVSPNSDAAAEKRFFDENFGPFFRAEQAFLVN--DTHQAGPGPVLSYETL 440
Query: 440 ELLFEIQEKV---DEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGG 496
+ ++++++ + + Y +L+D+C KP G+ C QS+ +F + G
Sbjct: 441 KWWEDVEKRIGSQESLDGKY-----TLNDVCYKPTGDACVIQSVTGWF--------SSTG 487
Query: 497 VEHAEYCFQHYTSTET-----CFSAFKAPLEPTTALGGF--SGNNYSEASAFIITYPVNN 549
++ ++ Q + C AF+ PL LGG+ + + + ASA + T+ V N
Sbjct: 488 IDQEDWAAQISKCAASPGDVDCLPAFQLPLPADRLLGGYNRTSDRATSASALVTTWVVQN 547
Query: 550 ALTKVGDEN-GKAIAWEKA 567
G+ KA WE++
Sbjct: 548 --YNAGEPGLAKAEKWERS 564
>K9HLF6_AGABB (tr|K9HLF6) Uncharacterized protein OS=Agaricus bisporus var.
bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389)
GN=AGABI2DRAFT_202338 PE=4 SV=1
Length = 1381
Score = 228 bits (580), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 174/586 (29%), Positives = 263/586 (44%), Gaps = 82/586 (13%)
Query: 41 YCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQL---- 94
+CA+ CG K L CPY P +P D A + +C G VCC+ +Q+
Sbjct: 3 HCALRSSCGTNV-FKPLPCPYEGPPQEPED--RALLTEVCGPEFAAGPVCCSSDQVETLK 59
Query: 95 ----QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGIDLYVT 149
Q L CPAC NF + FC +CSP+Q F+NVTS + +G V D +VT
Sbjct: 60 ANFVQVEAFLASCPACRNNFRSFFCAFTCSPHQGEFVNVTSTQEGSNGRTAVKSADFFVT 119
Query: 150 ETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKT 209
E FG+G Y +CKDV+FG N A+DF+G GA +Y +F FLG P GSP+ I+F T
Sbjct: 120 EQFGKGFYDSCKDVQFGVTNGYAMDFIGGGAKDYHAFFKFLGDVKP---LGSPFQINFPT 176
Query: 210 TILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR 268
T S+P + ++ +C+D+ L +G L
Sbjct: 177 T---STPDITPLDPPPRNCHDSELTSRCTCIDCPDMCPALPPAPLPNAGPTCLVGPLS-- 231
Query: 269 CVDLSLAVLYIVLVF-VLFGWIXXX--------XXXXXXXXGSSAEPLLVSEG------- 312
C+ L+V Y V V L G+ +A P S G
Sbjct: 232 CLSFILSVTYTVAVLGFLTGYAISAFRRHRREKSYERVALSADAASPRTRSHGLVGAASL 291
Query: 313 -----RSFTNLPKDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV 362
+ P + L ++DP + + I + + G +A+ P ++
Sbjct: 292 SHYIDEDSSGAPSENRHLGRGVSLLDPMETVQPRQDRINNVIRRGFYHLGLFASNHPWLM 351
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII-AT 421
++ LL G RF VET P +LWV P+S++ +KE+FD H PFYR EQ+ + A
Sbjct: 352 FSVVFLVIGLLNIGWDRFAVETDPVRLWVAPDSESRLQKEYFDQHFGPFYRTEQIFVTAA 411
Query: 422 LPESEH-------------GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICL 468
+P SE G+ +++ D ++ F+++ +IR S ++L D+C
Sbjct: 412 VPRSESNPNDTTQTTSITIGEKGPVLSWDRLKFWFDVES---QIRNLVSPNGLTLDDVCF 468
Query: 469 KPLGED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTA 526
KP G C TQSI ++ D +++D +H E C + C F+ PLEP
Sbjct: 469 KPGGPRGACVTQSIAAWYGNDLEDYDPDTWADHLEECAWNPVD---CLPDFQQPLEPQFV 525
Query: 527 LGGF-----SGNNYSEASAFIITYPVNNALTKVGDENGKAIA--WE 565
LGG Y EA AF++TY V+++L D++ +A+ WE
Sbjct: 526 LGGVPLDSKGSKQYLEAEAFVVTYVVSDSL----DQHKQAMIMDWE 567
>Q59ZV0_CANAL (tr|Q59ZV0) Potential sterol homeostasis protein OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) GN=NCR1 PE=4
SV=1
Length = 1256
Score = 228 bits (580), Expect = 7e-57, Method: Compositional matrix adjust.
Identities = 170/595 (28%), Positives = 276/595 (46%), Gaps = 67/595 (11%)
Query: 1 MENMSTAIISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNC 59
ME S+++I ++ + L + +L A +S S H YC Y CG++S GK L C
Sbjct: 1 MEFFSSSLILQA--MRAICLLLLTINLAIASVSSS-HKPGYCNTYGNCGKKSVFGKPLPC 57
Query: 60 PYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQLQAV--------PILVGCPACLRNFL 111
P+VK K++S+C +CC+ EQ+ + P++ CPAC +NF
Sbjct: 58 AEFVPAVKASQESREKLKSICGKDFDYICCSPEQIDILESNLKRVDPLISSCPACRKNFY 117
Query: 112 NLFCELSCSPNQSLFINV--TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMN 169
+ FC+ SCSPN+S F+ + T ++ G V I+ YV + +CK+VKF N
Sbjct: 118 DFFCQFSCSPNESQFVEIIKTETARDTGKEIVTEINQYVEPGMANQFFDSCKNVKFSATN 177
Query: 170 TRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDS-SPMELMNASVYSCN 228
A+D +G GA NY ++ FLG + P GSPY I+F + ++ S + L N + CN
Sbjct: 178 GYAMDLIGGGAKNYSQFLKFLGDE-KPLLGGSPYQINFVYKLPETDSGLVLRNEPLRDCN 236
Query: 229 DTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGW 288
D + + C S+ +++ ++ +L G+
Sbjct: 237 DKEYKCACTDCEESCPKLPHAKDLTKKCTVGV------LPCFSFSIIIIWSCMIVLLGGY 290
Query: 289 IXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDP------QRQNEVQYSF--- 339
L RS +D E +I+P ++ Q+S
Sbjct: 291 HVYLAK------------LKKERRRSIAEDSEDDESTMINPLFYAGLGKKRAKQFSSEIG 338
Query: 340 --IQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKA 397
IQ+W +N G + ++ P I + +SLA+V+LL GL + +ET P KLWV P A
Sbjct: 339 SKIQDWFANI----GYFCSKFPGISIGTSLAVVVLLSLGLFKLQLETDPVKLWVSPNDPA 394
Query: 398 AEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYS 457
+ +++F+S+ ++RIEQ+I++ S+ P ++ D ++ F+ + +++ + N
Sbjct: 395 YKNQQYFESNFGEWFRIEQVIVS----SKDDGP--VLNWDIVKWWFDKESQLETLNEN-- 446
Query: 458 GLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAF 517
V LSDIC KPL E CA QS QYFQ D + C S C F
Sbjct: 447 ---VRLSDICFKPLDETCALQSFTQYFQGDISGLTETNWKSKLQSCVD---SPVNCLPTF 500
Query: 518 KAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLA 572
+ PL+P F N+ S+A AF +T VN+ T+ + I++E +F + A
Sbjct: 501 QQPLKPNIL---FDSNDISQAKAFTVTVLVNSD-TQNENYTSNTISYEHSFQKWA 551
>C4YFP8_CANAW (tr|C4YFP8) Putative uncharacterized protein OS=Candida albicans
(strain WO-1) GN=CAWG_00024 PE=4 SV=1
Length = 1256
Score = 227 bits (579), Expect = 8e-57, Method: Compositional matrix adjust.
Identities = 170/584 (29%), Positives = 272/584 (46%), Gaps = 45/584 (7%)
Query: 1 MENMSTAIISVGFLLQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNC 59
ME S+++I ++ + L + +L A +S S H YC Y CG++S GK L C
Sbjct: 1 MEFFSSSLILQA--MRAISLLLLTINLAIASVSSS-HKPGYCNTYGNCGKKSVFGKPLPC 57
Query: 60 PYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQLQAV--------PILVGCPACLRNFL 111
P+VK K++S+C +CC+ EQ+ + P++ CPAC +NF
Sbjct: 58 AEFVPAVKASQESREKLKSICGKDFDYICCSPEQIDILESNLKRVDPLISSCPACRKNFY 117
Query: 112 NLFCELSCSPNQSLFINV--TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMN 169
+ FC+ SCSPN+S F+ + T ++ G V I+ YV + +CK+VKF N
Sbjct: 118 DFFCQFSCSPNESQFVEIIKTETARDTGKEIVTEINQYVEPGMANQFFDSCKNVKFSATN 177
Query: 170 TRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDS-SPMELMNASVYSCN 228
A+D +G GA NY ++ FLG + P GSPY I+F + ++ S + L N + CN
Sbjct: 178 GYAMDLIGGGAKNYSQFLKFLGDE-KPLLGGSPYQINFVYKLPETDSGLVLRNEPLRDCN 236
Query: 229 DTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGW 288
D + + C S+ +++ ++ +L G+
Sbjct: 237 DKEYKCACTDCEESCPKLPHAKDLTKKCTVGV------LPCFSFSIIIIWSCMIVLLGGY 290
Query: 289 IXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFY 348
S AE E L G Q +E+ S IQ+W +N
Sbjct: 291 HVYLAKLKKERRRSIAEDSEDDESTMINPLFYAGLGKKRAKQFSSEIG-SKIQDWFANI- 348
Query: 349 RAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHL 408
G + ++ P I + +SLA+V+LL GL + +ET P KLWV P A + +++F+S+
Sbjct: 349 ---GYFCSKFPGISIGTSLAVVVLLSLGLFKLQLETDPVKLWVSPNDPAYKNQQYFESNF 405
Query: 409 APFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICL 468
++RIEQ+I++ S+ P ++ D ++ F+ + +++ + N V LSDIC
Sbjct: 406 GEWFRIEQVIVS----SKDDGP--VLNWDIVKWWFDKESQLETLNEN-----VRLSDICF 454
Query: 469 KPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALG 528
KPL E CA QS QYFQ D + C S C F+ PL+P
Sbjct: 455 KPLDETCALQSFTQYFQGDISGLTETNWKSKLQSCVD---SPVNCLPTFQQPLKPNIL-- 509
Query: 529 GFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLA 572
F N+ S+A AF +T VN+ T+ + I++E +F + A
Sbjct: 510 -FDSNDISQAKAFTVTVLVNSD-TQNENYTSNTISYEHSFQKWA 551
>G8YM48_PICSO (tr|G8YM48) Piso0_001949 protein OS=Pichia sorbitophila (strain
ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 /
NRRL Y-12695) GN=Piso0_001949 PE=4 SV=1
Length = 1240
Score = 226 bits (575), Expect = 2e-56, Method: Compositional matrix adjust.
Identities = 165/552 (29%), Positives = 257/552 (46%), Gaps = 41/552 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H + YC MYD CG++S G L C + ++KP + +C + T VCC+E Q
Sbjct: 24 HQDGYCVMYDNCGKKSIFGSELPCVNYTRAIKPSSDAIKLLNEVCGSDFPTDLVCCSESQ 83
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS--ISQVDGNMTVDG 143
+ +A PI+ CPAC +NF N FC+ +CSPNQS F+N+T+ IS G V G
Sbjct: 84 IMDLGKNLKKAAPIISSCPACKKNFQNFFCDFTCSPNQSAFVNITNSGISSDKGKEIVTG 143
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+ Y+ F Y++CKDVKF N A+D +G GA N+KE+ FLG + P GSP+
Sbjct: 144 LTSYINPGFASRFYNSCKDVKFSATNGYAMDLIGGGARNFKEFLKFLGDE-KPLLGGSPF 202
Query: 204 SIDFKTTILDSSP---MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
I+++ I D++ + L + C+D G
Sbjct: 203 QINYEYEISDAAEKQGLRLAETHMRPCDDREYG----CSCSDCPTSCPELPKFKGFNGRC 258
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
++G K+ C L + L+ +V VL G + E SE R +
Sbjct: 259 RVG--KLPCFSLIVICLWTTIV-VLIGAYHVYLMKLKKNAWTELEREFESETRQVEHFCD 315
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
+ Q +E FI+ L +++ R +R P V+ SL + +L G+ +
Sbjct: 316 HDDSAKTTSQSYHE---KFIKT-LESYFERIARSCSRHPKNVIIISLFLSFILSCGISKI 371
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIE 440
+E P LWV P A +E ++F H ++RIEQLII++ ESE ++ DNI
Sbjct: 372 KLERNPINLWVSPNEPALKEMQYFQEHFGEWFRIEQLIISSKNESE-----PVLNWDNIA 426
Query: 441 LLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHA 500
FE ++++ G VS ++C KP E CA +S QYF+ D + + +
Sbjct: 427 WWFEKEKELANFEVE-EGESVSYDELCFKPTEETCAIESFTQYFRGDINYLNERNWKQKL 485
Query: 501 EYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK 560
+ C S C +F+ PL+ FS ++ +SAFI+T +NN + V K
Sbjct: 486 QSCTD---SPVNCLPSFQQPLKKNIL---FSSDDVLNSSAFIVTLLLNNNSSDV-KYTEK 538
Query: 561 AIAWEKAFIQLA 572
AI +E++ + A
Sbjct: 539 AIRYEQSLVAWA 550
>M2T643_COCSA (tr|M2T643) Uncharacterized protein OS=Bipolaris sorokiniana ND90Pr
GN=COCSADRAFT_160664 PE=4 SV=1
Length = 1271
Score = 225 bits (573), Expect = 4e-56, Method: Compositional matrix adjust.
Identities = 159/548 (29%), Positives = 247/548 (45%), Gaps = 32/548 (5%)
Query: 15 LQVLILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLS 73
+ V +LS + S A + H CAM CG++ G L CP P+ P D +
Sbjct: 12 MTVGLLSVLAGSALAGPDLTTRHERGRCAMRGQCGKQGFFGSELPCPDNGPAKTPDDDVR 71
Query: 74 AKIQSLCPT--ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQ 123
K+ +C T ++CC E+QL +A PI+ CPAC NF NLFC +CSP+Q
Sbjct: 72 KKLVEICGTQWSDSDICCDEDQLDALKTNLDRATPIINACPACKENFYNLFCTFTCSPDQ 131
Query: 124 SLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNY 183
S F+N+T V +D + + + Y +CKDVKFG N +A+DF+G GA N+
Sbjct: 132 STFVNITGTEPKGDKYLVTELDSLIADKYASTFYDSCKDVKFGATNGKAMDFIGGGAKNF 191
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXX 242
++ FLG K F GSP+ I++ + P M M+ Y C+
Sbjct: 192 TQFLKFLGDK---KFLGSPFQINYPRPSQELFPGMTAMSKHAYPCDTED---EKYRCACL 245
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFV-LFGWIXXXXXXXXXXXG 301
+G L LS AV+ I F+ L
Sbjct: 246 DCGTSCTELPAVQEGKQCHVGLLPC----LSFAVIIIYSCFIGLLCIAVAGHVAYQKHSR 301
Query: 302 SSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTI 361
E + + + S ++ +G+++ ++ F+ W + G A P I
Sbjct: 302 HKTERMRLLQDTSPSDDEDEGDIVHNVGMLDRPTKHYFVNTWCDRMFSRLGYICASFPAI 361
Query: 362 VLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT 421
+ +S+ +VIL+ G L+F +ET P LWV P+S AA+EK FFD PF+R EQ A
Sbjct: 362 TIITSIIVVILMSLGWLQFQIETDPVNLWVSPDSAAAQEKAFFDEKFGPFFRAEQ---AF 418
Query: 422 LPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSIL 481
L P +++ + ++ F ++ ++ +++ G V+L IC KP+G+DC QS+
Sbjct: 419 LVNDTLDSPGPVLSYETLDWWFGVENQIQRLKSAEHG--VTLDQICFKPVGDDCIVQSVT 476
Query: 482 QYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
YFQ D F N + Q + C F+ PL+P GG + +A A
Sbjct: 477 GYFQGD---FANVIPNSWKDDLLQCVDNPSQCLPTFQQPLDPHLLFGGVE-ESVLDAKAL 532
Query: 542 IITYPVNN 549
++T+ V N
Sbjct: 533 VVTWVVQN 540
>K5XB43_AGABU (tr|K5XB43) Uncharacterized protein OS=Agaricus bisporus var.
burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC 10392)
GN=AGABI1DRAFT_73742 PE=4 SV=1
Length = 1381
Score = 224 bits (572), Expect = 5e-56, Method: Compositional matrix adjust.
Identities = 173/586 (29%), Positives = 263/586 (44%), Gaps = 82/586 (13%)
Query: 41 YCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQL---- 94
+CA+ CG K L CPY P +P D A + +C G VCC+ +Q+
Sbjct: 3 HCALRSSCGTNV-FKPLPCPYEGPPQEPED--RALLTEVCGPEFAAGPVCCSSDQVETLK 59
Query: 95 ----QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGIDLYVT 149
Q L CPAC NF + FC +CSP+Q F+NVTS + +G V D +VT
Sbjct: 60 ANFVQVEAFLASCPACRNNFRSFFCAFTCSPHQGEFVNVTSTQEGSNGRTAVKSADFFVT 119
Query: 150 ETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKT 209
E FG+G Y +CKDV+FG N A+DF+G GA +Y +F FLG P GSP+ I+F T
Sbjct: 120 EQFGKGFYDSCKDVQFGVTNGYAMDFIGGGAKDYHAFFKFLGDVKP---LGSPFQINFPT 176
Query: 210 TILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR 268
T S+P + ++ +C D+ L +G L
Sbjct: 177 T---STPDITPLDPPPRNCYDSELTSRCTCIDCPDMCPALPPAPLPNAGPTCLVGPLS-- 231
Query: 269 CVDLSLAVLYIVLVF-VLFGWIXXX--------XXXXXXXXGSSAEPLLVSEG------- 312
C+ L+V Y V V L G+ +A P S G
Sbjct: 232 CLSFILSVTYTVAVLGFLTGYAISAFRRHRREKSYERVALSADAASPRTRSHGLVGAASL 291
Query: 313 -----RSFTNLPKDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV 362
+ P + L ++DP + + I + + G +A+ P ++
Sbjct: 292 SHYIDEDSSGAPSENRHLGRGVSLLDPMVTVQPRQDRINNVIRRGFYHLGLFASNHPWLM 351
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII-AT 421
++ LL G RF VET P +LWV P+S++ +KE+FD H PFYR EQ+ + A
Sbjct: 352 FSVVFLVIGLLNIGWDRFAVETDPVRLWVAPDSESRLQKEYFDQHFGPFYRTEQIFVTAA 411
Query: 422 LPESEH-------------GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICL 468
+P SE G+ +++ D ++ F+++ ++ + + +GL +L D+C
Sbjct: 412 VPRSESNSNDTTQTTSITIGEKEPVLSWDRLKFWFDVESQIRNL-VSPNGL--TLDDVCF 468
Query: 469 KPLGED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTA 526
KP G C TQSI ++ D +N+ +H E C + C F+ PLEP
Sbjct: 469 KPGGPRGACVTQSIAAWYGNDLENYGPDTWADHLEECAWNPVD---CLPDFQQPLEPQFV 525
Query: 527 LGGF-----SGNNYSEASAFIITYPVNNALTKVGDENGKAIA--WE 565
LGG Y EA AF++TY V+++L D++ +A+ WE
Sbjct: 526 LGGVPLDTKGSKQYLEAEAFVVTYVVSDSL----DQHKQAMIMDWE 567
>K2S489_MACPH (tr|K2S489) Uncharacterized protein OS=Macrophomina phaseolina
(strain MS6) GN=MPH_11389 PE=4 SV=1
Length = 1822
Score = 224 bits (571), Expect = 7e-56, Method: Compositional matrix adjust.
Identities = 156/549 (28%), Positives = 250/549 (45%), Gaps = 32/549 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA+ CG G L CP + P + K+ S+C +VCC EEQ
Sbjct: 573 HEKGRCAIRGHCGSEGFFGPQLPCPDNGLAKTPESDVREKLISVCGDKWADTDVCCEEEQ 632
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
+ A+ ++ CPAC NF NLFC +CSP+QSLF+NVT +G + V +D
Sbjct: 633 IDALQSNLKRAESLIASCPACKENFFNLFCTFTCSPDQSLFVNVTETKPKNGKLMVTELD 692
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+ +G Y +CKDVK G N A+D +G GA NY + FLG K F GSP+ +
Sbjct: 693 HVVSNDYGSRFYDSCKDVKVGATNGNAMDLIGGGAKNYTRFLKFLGDK---KFLGSPFQM 749
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F D ++ +CND+ +G L
Sbjct: 750 NFPDPS-DYPGLKPQTKGAKACNDSD---ERYRCACVDCPSVCPELPEVKEDKQCHVGVL 805
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ ++ ++Y V + +L + E + + + ++ +G+V+
Sbjct: 806 P--CLSFAVIIIYSVFILLLILAVSGHVAYQKHYQ-HKQERMRLLQDLEPSDDEDEGDVV 862
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ + + +W + G A P + + SS+ +V++L G LRF VET
Sbjct: 863 AAAGVLDSPTRKYKLNDWCDKVFSRLGYTCAEYPALTIVSSVIVVVILSLGWLRFTVETD 922
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P+S AAEEK FFD + PFYR EQ + ++ P +++ DN+ F++
Sbjct: 923 PVRLWVSPDSAAAEEKAFFDENFGPFYRAEQAFLVN--DTNPSGPGPVLSYDNLGWWFDV 980
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
+ +V+ + + ++ D+C KP+G+ C QS+ YF D N + C
Sbjct: 981 ERRVNRLMIDD----ITFDDVCFKPVGDACVVQSVTGYFGGDFFNVNPKTWQHDLRACVD 1036
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
S C F+ PL P+ GG+ N+ EA A I+++ VNN + +E +A+ WE
Sbjct: 1037 ---SPVDCLPDFQQPLNPSMLFGGYK-NDVLEAEALIVSWVVNN-YQEGTEELERAMKWE 1091
Query: 566 KAFIQLAKV 574
+ L +
Sbjct: 1092 NSLKSLLRA 1100
>K1QD13_CRAGI (tr|K1QD13) Niemann-Pick C1 protein OS=Crassostrea gigas
GN=CGI_10004512 PE=4 SV=1
Length = 2678
Score = 224 bits (570), Expect = 1e-55, Method: Compositional matrix adjust.
Identities = 176/607 (28%), Positives = 274/607 (45%), Gaps = 87/607 (14%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKI-QSLCPT-ITGN---VCCTEEQLQA 96
C Y C GK+ NC Y P D + I ++ CP +TGN CC QL
Sbjct: 1666 CIWYGECENTPSGKI-NCQYNGPPKVMEDPVGMDILRTYCPDLVTGNQTKTCCDVNQLHT 1724
Query: 97 VPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-VDGIDLY 147
+ +G CP+C NFLNL+C L+C P+QS F+ N T V ++ Y
Sbjct: 1725 LQSNMGLPQQFFLRCPSCYNNFLNLYCYLTCGPHQSRFLQSNGTEVTPANKTAVKAVNYY 1784
Query: 148 VTETFGEGLYSACKDVKFGTMNTRAID-FVGAGANNYKE--WFAFLGQKVPPGFPGSPYS 204
+T + G++++CKDV+ + N +A+ F G A+ W +++G +P++
Sbjct: 1785 LTNEYANGMFNSCKDVQMPSANEKALSVFCGRPADQCSAELWLSYMGSTANGH---TPFT 1841
Query: 205 IDF----KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
I+F + ++ MN ++ CN S
Sbjct: 1842 INFAIGDQNVTQGNTTYVPMNYTITGCNQ-SYKNRSVCSCQDCEASCAPVPPIPPKPEPC 1900
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXG----SSAEPLLVSEGRSFT 316
K+ L + C + A+ + LVF LF +I S L E ++
Sbjct: 1901 KI--LHIDCYYFAFAI--VCLVFNLFFFIYVICYNILVRNSLDVMDSQYSRLEDEDGDYS 1956
Query: 317 NL----------PKDGEVLVIDPQRQN------EVQYSFIQEWLSNFYRAYGRWAARRPT 360
+ P+ G + P+ + E S+++ L +F+ A+G + AR P
Sbjct: 1957 GVFCVNGDGKKRPRPGAQRINAPKVSHADISCLEKTGSWMETLLESFFNAWGTFCARHPI 2016
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
+V+ LA+ L G+ F V T P KLW +S+A E+++FDSH PFYR EQLII
Sbjct: 2017 LVMVVGLAVAGSLSAGISVFQVTTDPVKLWSAKDSQARTERDYFDSHFGPFYRTEQLII- 2075
Query: 421 TLPESE----HGKPP---------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDIC 467
T P + H PP SI + + ++ ++Q ++ + A Y+G V+L DIC
Sbjct: 2076 TRPNNHTNVVHKNPPPSVDTVNYTSIFDKEFLHMVLDLQLAIENLTAEYNGETVTLEDIC 2135
Query: 468 LKPLGED---CATQSILQYFQMDPDN-----FDNYG------GVEHAEYCFQHYTSTE-- 511
+PL D C QSILQY+Q + N D YG ++H YC Q ST+
Sbjct: 2136 FQPLAPDNTKCTIQSILQYYQNNHTNIDKVVMDKYGFFVIADYIDHLRYCLQAPASTQDT 2195
Query: 512 -----TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEK 566
+C + P+ P +LGG+ GN+Y + A +IT+ VNN L + ++N KA AWEK
Sbjct: 2196 VGLNMSCLAESGQPIFPWISLGGYKGNDYKSSEALVITFVVNNHLAE--EKNKKAEAWEK 2253
Query: 567 AFIQLAK 573
FI+ +
Sbjct: 2254 VFIEKMR 2260
>K7TVT2_MAIZE (tr|K7TVT2) Uncharacterized protein OS=Zea mays GN=ZEAMMB73_147965
PE=4 SV=1
Length = 1200
Score = 223 bits (568), Expect = 2e-55, Method: Compositional matrix adjust.
Identities = 105/178 (58%), Positives = 139/178 (78%), Gaps = 3/178 (1%)
Query: 398 AEEKEFFDSHLAPFYR-IEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANY 456
A +E D + F + + QL++AT S + PSIV D+N++LLFEIQ+KVD++RANY
Sbjct: 1012 ALSQEALDEYSRIFSKSLSQLVLATS-ASGGSEAPSIVNDNNMKLLFEIQKKVDDLRANY 1070
Query: 457 SGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSA 516
SG V+L+DICLKPL DCATQS+LQYFQ+DP FD+ G++HA++CFQHYTS ETC S
Sbjct: 1071 SGSKVALADICLKPLSTDCATQSVLQYFQLDPKKFDD-SGIDHAKFCFQHYTSEETCLST 1129
Query: 517 FKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAKV 574
F++P++P+T LGGF G+N++EASAF+ITYPVNN + G ENGKA+AWE+AFI L KV
Sbjct: 1130 FQSPVDPSTILGGFPGSNFTEASAFVITYPVNNKVQTTGKENGKAMAWERAFINLVKV 1187
>H6CBA3_EXODN (tr|H6CBA3) Patched 1 OS=Exophiala dermatitidis (strain ATCC 34100
/ CBS 525.76 / NIH/UT8656) GN=HMPREF1120_08990 PE=4 SV=1
Length = 1268
Score = 222 bits (566), Expect = 3e-55, Method: Compositional matrix adjust.
Identities = 163/547 (29%), Positives = 248/547 (45%), Gaps = 53/547 (9%)
Query: 27 LTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI-- 83
L A+ + +H CA+ CG++ G L CP +V P + + K+ LC
Sbjct: 19 LAASSGATPLHEAGRCAIRGHCGKQGFFGSDLPCPDNGKAVPPTEAIRDKLVDLCGPKWE 78
Query: 84 TGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV 135
+VCC EEQ+ A+ IL CPAC NF NLFC +CSP+QSLF+NVT +
Sbjct: 79 DTDVCCEEEQVDALRKNLKLAERILASCPACKENFFNLFCTFTCSPDQSLFVNVTQTGKA 138
Query: 136 -DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKV 194
+G V ID ++ + G Y +CK+VK G +A+ F+G GA NY E+ FLG K
Sbjct: 139 SNGKEVVTEIDNVWSKHYQSGFYDSCKEVKNGASGGKAMAFIGGGAENYTEFLKFLGDK- 197
Query: 195 PPGFPGSPYSIDF--KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
GSP+ I+F + D M + VY+CNDT
Sbjct: 198 --KLLGSPFQINFPEEPRYDDKQGMVASDPRVYACNDTD---PNFRCSCVDCPEVCPTLE 252
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
+G K+ C+ S+ ++Y V + +L I + L+ +
Sbjct: 253 PVRSVEYCHVG--KLPCLSFSIIIVYSVALLLLIAAISGHVAYRRHKQRKTERLQLLQDA 310
Query: 313 RSFTNLPKDGE---VLVID------PQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVL 363
P D E LV D PQR ++ L + G + AR P + +
Sbjct: 311 -----APSDSEDEGDLVHDAGFLERPQRN-----YYLNLILDRAFNRLGGFCARYPALTI 360
Query: 364 CSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLP 423
+++ + LL G LRF VE P +LWV P S AA+EK FFD++ PFYR EQ +
Sbjct: 361 GTNIVFIGLLSLGWLRFQVERDPVRLWVSPTSDAAQEKAFFDTNFGPFYRTEQAFLV--- 417
Query: 424 ESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQY 483
++ S+++ + + F++++++ + G ++L D+C KP G C QS+ +
Sbjct: 418 -NDSSANSSVLSYETLSWWFDVEDRISRMMTPEHG--ITLKDVCFKPTGTACVVQSVSGW 474
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFI 542
F + E E C H + C F PL P LGG+ S ++ + + A I
Sbjct: 475 FGAGLTS----DWKEQIELCAAH-PGDQRCLPEFMDPLPPGRVLGGYDSIDDVASSKALI 529
Query: 543 ITYPVNN 549
T+ VNN
Sbjct: 530 TTWVVNN 536
>D8PKB4_SCHCM (tr|D8PKB4) Putative uncharacterized protein OS=Schizophyllum
commune (strain H4-8 / FGSC 9210) GN=SCHCODRAFT_46894
PE=4 SV=1
Length = 1374
Score = 222 bits (566), Expect = 3e-55, Method: Compositional matrix adjust.
Identities = 165/579 (28%), Positives = 259/579 (44%), Gaps = 77/579 (13%)
Query: 42 CAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKI-QSLCPT--ITGNVCCTEEQLQAV 97
CAM CG++ GK L CPY P+V+P D + K+ +C G CCT QL+ +
Sbjct: 10 CAMRSSCGRKGFFGKELPCPYDGPAVEPEDAETRKLLADVCGAEFAEGPTCCTSGQLETL 69
Query: 98 P--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD-GNMTVDGIDLYV 148
I+ CPAC NF + FC +CSP+Q+ F+N+T + G V +D +V
Sbjct: 70 RDNFATVDNIISSCPACRNNFHSFFCSFTCSPDQATFVNITETQKSQTGETAVKSLDFFV 129
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
E + +G + +CK V+ G N A+D +G GA +YK + FLG + GSP+ I+F
Sbjct: 130 EEQYAKGFFDSCKSVQVGATNGYAMDLIGGGAKDYKAFLKFLGDEKD---IGSPFQINFP 186
Query: 209 TTILDSSPMELM--NASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLK 266
+P E NA+ +C D L +G+
Sbjct: 187 ----HDTPSEFTAYNATPRNCADNDLASRCTCIDCPDICPTRPPIDPPGGGPTCHVGA-- 240
Query: 267 VRCVDLSLAVLY-IVLVFVLFGWIXXXX----------XXXXXXXGSSAEPL-----LVS 310
+ C+ L + Y + +V LFG++ +S P LV
Sbjct: 241 ISCLTFVLTLTYGLAVVGFLFGYLIEITIRKRRERLYERVALSVDNASISPRSNTRGLVG 300
Query: 311 EG----------RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPT 360
G RS + V ++DP + + +Q +L + G +AA P
Sbjct: 301 AGSLAHYVDEPARSASEHDLGPRVALLDPVETVQPRQFPLQNFLRRMFYRLGLFAAGYPW 360
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
+ LL G RF VET P +LWV P S++ ++KEFFD H PFYR +Q+ +
Sbjct: 361 ATFALVFTAIGLLNIGWKRFEVETDPVRLWVAPTSESKQQKEFFDEHFGPFYRAQQIFVT 420
Query: 421 TLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRA---NYSGLLVSLSDICLKPLGED--C 475
+E +P +T D +E F+++ ++ E+++ NY +L D+C KP G + C
Sbjct: 421 ----AEEDEP--AMTFDRLEYWFDVEREIRELKSSPHNY-----TLDDVCFKPAGSEGAC 469
Query: 476 ATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNN 534
QS+ +F + +D EH + C S C F+ PL P LGG G N
Sbjct: 470 VFQSVGAWFDTSLEGYDEDTWAEHVQQC---ALSPVECLPDFQQPLSPEFVLGGVPQGEN 526
Query: 535 -----YSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
Y++A+A ++ V+++L ++ KA+ WE A
Sbjct: 527 DTTPRYTDAAAMVVNIVVSDSLDEI--VQAKAMEWETAL 563
>N1Q2D3_MYCPJ (tr|N1Q2D3) Uncharacterized protein OS=Dothistroma septosporum
NZE10 GN=DOTSEDRAFT_68660 PE=4 SV=1
Length = 1276
Score = 222 bits (565), Expect = 4e-55, Method: Compositional matrix adjust.
Identities = 162/574 (28%), Positives = 258/574 (44%), Gaps = 41/574 (7%)
Query: 19 ILSWFSPSLTAAQ-ISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKI 76
I + SP+ A + I + H CA+ CG++S G L CP + P + + +
Sbjct: 12 IAHFISPATAANEPIWTTKHEAGRCAIRGQCGKQSFFGSELPCPDNGLAEDPSEKVRDDL 71
Query: 77 QSLCPT--ITGNVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLF 126
LC VCC +Q++A+ ++ GC AC +NF +LFC +CSP+QSLF
Sbjct: 72 VKLCGPEWADTKVCCDGDQIEALRSNLAKANGLISGCGACKKNFYDLFCTFTCSPDQSLF 131
Query: 127 INVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEW 186
+NVT +D +++ FG G Y +CKDVK G +AID +G GA NY ++
Sbjct: 132 VNVTKAESKGDKFITTELDQLISDGFGTGFYDSCKDVKLGATGGKAIDLIGGGAKNYTQF 191
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXX 246
FLG K P GSP+ IDF + M+ + CN T
Sbjct: 192 LKFLGDKKP---FGSPFQIDFPRPVDGLKGMKPILEDPIPCNTTD---EAYRCSCVDCAG 245
Query: 247 XXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+G L C+ ++ V+Y V + +L + S E
Sbjct: 246 SCPTLPKVTEAEQCAVGLLP--CLSFAIVVIYSVFITLLVLAVTGHVAAAKRRQ-SKNER 302
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
L + + + ++ +G+++ + + + + R AR P I + +S
Sbjct: 303 LQLLQDSAPSDDEDEGDMVHSVAMTDRPTKQYVVNTYCDRVFANLARTCARFPGITIGTS 362
Query: 367 LAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESE 426
IV LL G LRF VET P KLWV P+S AA EKEFFD++ PF+R EQ + ++
Sbjct: 363 FLIVGLLSLGWLRFAVETDPVKLWVAPDSAAASEKEFFDTNFGPFFRTEQAFLVN--DTT 420
Query: 427 HGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQM 486
P +++ + ++ F+++ ++ ++ +G +L D+C P GE C QS+ YF
Sbjct: 421 DAGPSPVLSYNTLQWWFDVERRIRVQKSFGNGY--TLKDVCYNPTGEACVVQSVSGYFAS 478
Query: 487 DPDNFDNYGGVEHAEYCFQHYTSTET-----CFSAFKAPLEPTTALGGF--SGNNYSEAS 539
G+ A + Q ET C FK PL LGG+ + + ++A+
Sbjct: 479 T--------GLNEATWDEQLNNCAETPGDVQCLPEFKLPLPAERLLGGYNRTSQHATDAA 530
Query: 540 AFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
A + T+ + N D KA WE++ +L K
Sbjct: 531 ALVTTWVITN-YNPDDDRLEKAEEWEESTKRLFK 563
>E9E0K2_METAQ (tr|E9E0K2) Patched sphingolipid transporter OS=Metarhizium acridum
(strain CQMa 102) GN=MAC_03400 PE=4 SV=1
Length = 1269
Score = 221 bits (563), Expect = 6e-55, Method: Compositional matrix adjust.
Identities = 153/541 (28%), Positives = 248/541 (45%), Gaps = 38/541 (7%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P L ++ LC G V + +
Sbjct: 31 HEAGRCAFRGQCGKQSFFGKELPCVDNDVAKDPDAELRKELVDLCGAEWNQGPVQSLKSE 90
Query: 94 LQAVPILVG-CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETF 152
L L+G CPAC NF N+FC+ +CSP+QSLF+NVT + +G + V +D ++E +
Sbjct: 91 LGTPNTLIGSCPACKHNFFNMFCKFTCSPDQSLFVNVTDAAPKNGKLLVTELDQLISEEY 150
Query: 153 GEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTIL 212
G GLY +CK+VKFG N+RA+D +G GA NY + FLG K P GSP+ I++ +
Sbjct: 151 GTGLYDSCKEVKFGGANSRAMDLIGGGAKNYHQMLKFLGDKKP--LVGSPFQINYPES-Y 207
Query: 213 DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR---C 269
+ M ++ + CND + GS V C
Sbjct: 208 EQPNMGPLDMAPKKCNDEDPDYRCVCVDCPAVCPELPAVR--------RSGSCHVGVLPC 259
Query: 270 VDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDP 329
+ + Y VL+F + L+ E S ++ +G ++ +
Sbjct: 260 LSFASIFTYSVLLFTFAASVFGHVAWRRYAQHRVERTRLLHES-SHSDDEDEGGPVLTEA 318
Query: 330 QRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKL 389
R + +I + + + G A+R P + + +SL IV +L G +F++E P +L
Sbjct: 319 MRDRPTKRYWINDRCDDLFYRLGHTASRFPGLTIGTSLLIVAILSAGWFKFDLEKEPARL 378
Query: 390 WVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKV 449
WV P S AA+EK +FDSH PFYR E++ + +++ G P +++ + + E+++ +
Sbjct: 379 WVSPSSPAAQEKAYFDSHFGPFYRAEKIFLVN--DTQPGGPGPVLSYETLRWWAEVEKSI 436
Query: 450 DEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTS 509
++ + L D+C KP+ + C QS+ Y+ + + C + S
Sbjct: 437 AQLESKTYAKY--LDDVCFKPMNDACVVQSVTGYWFAKGGVINPKTWKDDLRQCAK---S 491
Query: 510 TETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK-----AIAW 564
C F P+EP+ GG+ ++ +EA A T+ V NA E G AI W
Sbjct: 492 PVDCRPEFGQPIEPSMVFGGYQ-DDVTEAQAITATWVVRNA------EEGSFAQLAAIDW 544
Query: 565 E 565
E
Sbjct: 545 E 545
>G8YBA4_PICSO (tr|G8YBA4) Piso0_001949 protein OS=Pichia sorbitophila (strain
ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 /
NRRL Y-12695) GN=Piso0_001949 PE=4 SV=1
Length = 1240
Score = 221 bits (562), Expect = 7e-55, Method: Compositional matrix adjust.
Identities = 161/555 (29%), Positives = 257/555 (46%), Gaps = 47/555 (8%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H + +C MYD CG++S G L C + ++KP + +C + T VCC+E Q
Sbjct: 24 HRDGFCVMYDNCGKKSIFGSELPCVNYTRAIKPSSDAIQLLNEVCGSDFPTDLVCCSESQ 83
Query: 94 L--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS--ISQVDGNMTVDG 143
+ +A PI+ CPAC +NF N FC+ +CSPNQS F+N+T IS G V
Sbjct: 84 IMDLGKNLKKAAPIISSCPACKKNFQNFFCDFTCSPNQSAFVNITKSGISSDKGKEIVTE 143
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+ Y+ F Y +CKDVKF N A+D +G GA N+KE+ FLG + P GSP+
Sbjct: 144 LTSYINPDFASRFYDSCKDVKFSATNGYAMDLIGGGARNFKEFLKFLGDE-KPLLGGSPF 202
Query: 204 SIDFKTTILDSSP---MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
I+++ + D++ + L + + C+D G
Sbjct: 203 QINYEYQLSDTAEKQGLRLAESHIRPCDDRDYG----CSCSDCPTSCPDLPKFKGFNGRC 258
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
++G K+ C L + L+ +V VL G + E SE R +
Sbjct: 259 RVG--KLPCFSLIVICLWTTIV-VLIGAYHVYLIKLKKNAWNELEREFESETRQVEHFCD 315
Query: 321 DGEVLVIDPQRQNEVQY---SFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGL 377
D Q QY FI+ L +++ R ++ P V+ SL + + G+
Sbjct: 316 H------DDSAQTSFQYYHEKFIKT-LESYFERIARLCSKHPKNVIIISLFLSFIFSCGI 368
Query: 378 LRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD 437
+ +E P LWV P+ A +E ++F H ++RIEQLII++ +SE ++
Sbjct: 369 SKIKLERNPINLWVSPDEPALKEMQYFQEHFGEWFRIEQLIISSKNQSE-----PVLNWG 423
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
NI FE ++++ + G +VS ++C KP E CA +S QYF+ D + +
Sbjct: 424 NIAWWFEKEKELAKFEVG-DGEVVSYDELCFKPTEETCAIESFTQYFKGDINYLNERNWK 482
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDE 557
+ + C S C +F+ PL+ FS ++ +SAFI+T VNN + V +
Sbjct: 483 QKLQSC---ADSPVNCLPSFQQPLKKNIL---FSSDDVLNSSAFIVTLLVNNNSSDV-EH 535
Query: 558 NGKAIAWEKAFIQLA 572
KAI +E++ + A
Sbjct: 536 TKKAIQYEQSLVAWA 550
>L8FXE1_GEOD2 (tr|L8FXE1) Uncharacterized protein OS=Geomyces destructans (strain
ATCC MYA-4855 / 20631-21) GN=GMDG_01652 PE=4 SV=1
Length = 1275
Score = 220 bits (561), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 168/562 (29%), Positives = 251/562 (44%), Gaps = 46/562 (8%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCP------YPSPSVKPHDL-LSAKIQ 77
S T A IH CA+ CG++S G L CP PSP + H + L
Sbjct: 16 SSTVADPYTPIHEAGRCAIRGTCGKKSFFGPELPCPDNGLAEEPSPETRKHLVELCGSKW 75
Query: 78 SLCPTITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINV 129
S CP VCC +QL +A PI+ CPAC NF NLFC +CSP+QSLFINV
Sbjct: 76 SECP-----VCCEGKQLDDLETNLKRAQPIISACPACKDNFFNLFCTFTCSPDQSLFINV 130
Query: 130 TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAF 189
T + V +D V+ +G G Y +CKDVKFG N A+DF+G GA +Y F
Sbjct: 131 TETEKKGDKSIVTELDQLVSVKYGSGFYDSCKDVKFGAANQNAMDFIGGGAKDYPGLLKF 190
Query: 190 LGQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXX 248
LG K GSP+ I+F + P M+ + CND
Sbjct: 191 LGDK--KLLVGSPFQINFPLPTDYTEPNMKPTDMVPKKCNDED---EAFRCACVDCPAVC 245
Query: 249 XXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL 308
+G L C+ + Y + + +L I + L
Sbjct: 246 PKLEEVKENKACHVGPLP--CLSFGAILTYGIFLALLATAIFGHVAWAKHSRRRNQRLQL 303
Query: 309 VSEGRSFTNLPKDGEVL----VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLC 364
+ + + + ++G++L + D +QN + I S G AA P I +
Sbjct: 304 LQDIAASDDEDEEGDLLDNAALYDRPQQNYRVNTIIDSAFSKL----GYAAASFPGISIG 359
Query: 365 SSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPE 424
S+ IV L G + F++E P +LWV P S AA+EK FFD PFYR EQ+ + +
Sbjct: 360 LSVLIVALFSLGWMNFDIEKNPARLWVSPASDAAKEKAFFDESFGPFYRAEQVFLVN--D 417
Query: 425 SEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYF 484
+ G P +++ + ++ F+++++V ++ + G L+D+C KP+G+ C QS+ YF
Sbjct: 418 THPGGPGPVLSYETLKWWFDVEDRVSKLTGPHYG--AKLNDVCFKPMGDACVIQSVTGYF 475
Query: 485 QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFII 543
D + + C + S C PL P T LGG+ + +++A I
Sbjct: 476 GNDISTVNPKTWKSDLKGCAK---SPVLCRPESGQPLPPNTILGGWEESGDVIDSTALIA 532
Query: 544 TYPVNNALTKVGDENGKAIAWE 565
T+ VNN + E +A+ WE
Sbjct: 533 TWVVNN-YAEGSPETERAMDWE 553
>E9ENZ2_METAR (tr|E9ENZ2) Patched sphingolipid transporter OS=Metarhizium
anisopliae (strain ARSEF 23 / ATCC MYA-3075)
GN=MAA_02001 PE=4 SV=1
Length = 1269
Score = 219 bits (558), Expect = 2e-54, Method: Compositional matrix adjust.
Identities = 151/544 (27%), Positives = 249/544 (45%), Gaps = 38/544 (6%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEEQ 93
H CA CG++S GK L C + P L ++ LC G V + +
Sbjct: 31 HEAGRCAFRGQCGKQSFFGKELPCVDNDVAKDPDAELRKELVDLCGAEWNQGPVQSLKSE 90
Query: 94 LQAVPILVG-CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETF 152
L L+G CPAC NF N+FC+ +CSP+QSLF+NVT + +G + V +D ++E +
Sbjct: 91 LGTPNTLIGSCPACKHNFFNMFCKFTCSPDQSLFVNVTDAAPKNGKLLVTELDQLISEEY 150
Query: 153 GEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTIL 212
G GLY +CK+VKFG N+RA+D +G GA +Y + FLG K P GSP+ I++ +
Sbjct: 151 GTGLYDSCKEVKFGGANSRAMDLIGGGAKDYHQMLKFLGDKKP--LVGSPFQINYPES-Y 207
Query: 213 DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR---C 269
+ M ++ + CND K GS V C
Sbjct: 208 EQPNMGPLDMTSKKCNDEDPDYRCVCVDCPAVCPELPAVR--------KSGSCHVGALPC 259
Query: 270 VDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDP 329
+ + Y VL+F + L+ E S ++ +G ++ +
Sbjct: 260 LSFASIFTYSVLLFTFAASVFGHVAWRRYAQHRVERTRLLHES-SHSDDEDEGGPVLTEA 318
Query: 330 QRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKL 389
R + +I + + + G A+R P + + +SL +V +L G +F++E P +L
Sbjct: 319 MRDRPTKRYWINDRCDDLFYRLGHTASRFPGLTIGTSLLVVAILSAGWFKFDLEKEPARL 378
Query: 390 WVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKV 449
WV P S AA+EK +FDSH PFYR E++ + +++ P +++ + ++ E+++ +
Sbjct: 379 WVSPSSPAAQEKAYFDSHFGPFYRAEKIFLVN--DTQPSGPGPVLSYETLKWWAEVEKSI 436
Query: 450 DEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTS 509
++ + L D+C KP+ + C QS+ Y+ + + C + S
Sbjct: 437 AQLESKTYAKF--LHDVCFKPMNDACVVQSVTGYWFAKGGVINPKTWKDDLRQCAK---S 491
Query: 510 TETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGK-----AIAW 564
C F P+EP+ GG+ ++ +EA A T+ V NA E G A+ W
Sbjct: 492 PVDCRPEFGQPIEPSMVFGGYE-DDVTEAQAITATWVVRNA------EEGSFAQLAAVDW 544
Query: 565 EKAF 568
E A
Sbjct: 545 ENAL 548
>J4UQG8_BEAB2 (tr|J4UQG8) Patched sphingolipid transporter OS=Beauveria bassiana
(strain ARSEF 2860) GN=BBA_03387 PE=4 SV=1
Length = 1271
Score = 218 bits (555), Expect = 6e-54, Method: Compositional matrix adjust.
Identities = 160/555 (28%), Positives = 255/555 (45%), Gaps = 34/555 (6%)
Query: 24 SPSLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT 82
S +L +AQ H CA CG++S GK L C + P L +++ LC
Sbjct: 17 STALVSAQDYTPKHEQGRCAFRGQCGKQSFFGKELPCVDNGLAQNPEAELRSELIELCGE 76
Query: 83 --ITGNVCCTEEQLQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSI 132
G VCCT Q+QA+ +G CPAC NF N FC+ +CSP+QSLF+N+TS
Sbjct: 77 EWREGPVCCTLPQVQALKSELGTPNTLIGSCPACKHNFFNTFCKFTCSPDQSLFVNITSA 136
Query: 133 SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQ 192
++ N+ V +D +++ +G G Y +CK+VKFG N+RA++ +G GA YK + FLG
Sbjct: 137 AEKGDNLLVTELDHLISDEYGAGFYDSCKEVKFGGANSRAMNLIGGGAKEYKAFLKFLGD 196
Query: 193 KVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
K P F GSP+ ++F T D M ++ CND
Sbjct: 197 KKP--FAGSPFQMNFPRT-YDDPAMRPLDMKPKKCNDED---PDYRCVCVDCPEVCPDLP 250
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
++G+L C+ + +Y VL+F L + + L+ E
Sbjct: 251 EVKKNRSCRVGALP--CLSFASVFVYSVLLFALAALLSGHVAWKKYSMRKAERTRLLHEA 308
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
S ++ +G + + R V+ ++ + + G AA P + + L +V +
Sbjct: 309 -SHSDDEDEGGPVHSEAMRDRPVKRYWLNDRCDKAFYQLGLSAASSPALTISICLVVVAV 367
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
L G + F++E P +LWV P S AA+EK +FD + PFYR EQ + ++ P
Sbjct: 368 LSAGWVHFDLEKEPARLWVSPSSAAAQEKAYFDDNFGPFYRAEQAFLVN--DTISDGPSP 425
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
+++ + ++ ++ + + + G L D+C KP + C QS+ Y+ F
Sbjct: 426 VLSYETLQWWIGVERSIQNLESPTYGKY--LRDLCFKPTNDACVVQSVSAYWG-SKGGFG 482
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALT 552
+ C + S C F P+EP LGG+ ++ +EA A +T+ VNNA
Sbjct: 483 RETWQDELRACAK---SPVECRPEFGQPIEPEMILGGYE-SDVAEAKAITVTWVVNNA-- 536
Query: 553 KVGD--ENGKAIAWE 565
GD E A+ WE
Sbjct: 537 -PGDTTEFAHAVDWE 550
>F1QNG7_DANRE (tr|F1QNG7) Uncharacterized protein OS=Danio rerio GN=npc1 PE=4
SV=1
Length = 1276
Score = 216 bits (551), Expect = 1e-53, Method: Compositional matrix adjust.
Identities = 172/597 (28%), Positives = 265/597 (44%), Gaps = 58/597 (9%)
Query: 23 FSPSLTAAQISRSIHSNEYCAMYDICGQRSD--GKVLNCPYPSPSVKPHDLLSAKIQSLC 80
F L +S +H ++C Y CG + K LNC Y P+V + +Q LC
Sbjct: 10 FRLLLATVLLSHWVHG-QHCIWYGECGNSPNVPEKKLNCNYTGPAVPLPNEGQELLQELC 68
Query: 81 PTIT---GNVCCTEEQLQA------VPI--LVGCPACLRNFLNLFCELSCSPNQSLFINV 129
P + VCC +QL +P+ L CPAC NF+ LFCEL+CSP QS FI+V
Sbjct: 69 PRLVYADNRVCCDTQQLNTLKSNIQIPLQYLSRCPACFFNFMTLFCELTCSPRQSQFISV 128
Query: 130 TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEW 186
+ +V + Y+T+TF + +++AC+DV+ + N +A+ + A + W
Sbjct: 129 KDFLKEKNQTSVGNVTYYITQTFADAMFNACRDVQAPSSNIKALGLLCGRDASVCTPQIW 188
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDT-SLGXXXXXXXXXXXX 245
++ + G P+ I+ T + M MN ++C+ + G
Sbjct: 189 IQYMF-SISNG--QVPFGIEPIFTDVPVQGMTPMNNRTFNCSQSLDDGSEPCSCQDCSEV 245
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAE 305
I +G + + + YI + + FG + S
Sbjct: 246 CGPTPVPPPIPPPWIILG---LDAMSFIMWCSYIAFLLIFFGVVLGAWCYRRSVVTSEYG 302
Query: 306 PLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCS 365
P+L S +L DG L ID E + L + +G R+P ++ S
Sbjct: 303 PILDSNQPH--SLNSDGTDL-IDEASCCETVGERFENSLRLVFSRWGSLCVRQPLTIILS 359
Query: 366 SLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
SL ++ + GL + T P +LW P S+A +EK +FD H PF+R EQLII T P +
Sbjct: 360 SLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNYFDQHFGPFFRTEQLIITT-PWT 418
Query: 426 EHGKPPSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---G 472
E G +I D N+ LL ++ Q +++ + A Y G V+L DIC+ PL
Sbjct: 419 EEGGFSTITGDIIPFSPILNLSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYN 478
Query: 473 EDCATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTSTET-------CFSA 516
++C S+L YFQ + D+ E H YC TS + C
Sbjct: 479 DNCTILSVLNYFQNSHEVLDHEFQDEFFLYNDYHTHLLYCASSPTSLDDTSRLHDPCMGT 538
Query: 517 FKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
F P+ P LGG+ + Y+ A+A +IT+PV N L ++ GKA+AWEK FI+ K
Sbjct: 539 FGGPVFPWLVLGGYEDSAYNNATALVITFPVTNYLNDT-EKLGKALAWEKEFIRFMK 594
>N1JI99_ERYGR (tr|N1JI99) Niemann-Pick C1 protein OS=Blumeria graminis f. sp.
hordei DH14 GN=BGHDH14_bgh02031 PE=4 SV=1
Length = 1277
Score = 216 bits (549), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 154/549 (28%), Positives = 248/549 (45%), Gaps = 41/549 (7%)
Query: 36 IHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEE 92
+H CA+ CG S + C Y + +P + K+ LC + +G VCC E
Sbjct: 27 LHEAGRCAIRGNCGGGSIFSPPIPCSYNGQAEEPATDVREKLVELCGSKWSSGPVCCEES 86
Query: 93 QLQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGI 144
Q+Q A + CPAC NF NLFC +CSP+QSLF+NVT + V +
Sbjct: 87 QIQSLSDNLNKAKSFISACPACKENFYNLFCTFTCSPDQSLFLNVTEAKAYGTKLQVAEL 146
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
D + + GL+ +CKDVKFG NT A+DF+G GAN++ ++ F+G+K PP GSP+
Sbjct: 147 DQLLDTEYASGLFDSCKDVKFGPTNTNAMDFIGGGANSFVDFLNFVGKKNPPF--GSPFQ 204
Query: 205 I------DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
I D+K D P ++ C+D
Sbjct: 205 INFPDPDDYKEK--DMKPQTMIPKE---CDDED---ERFRCACVDCLKVCPALPEIPRHE 256
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
+G L LS + + + LF I +E L + + S +
Sbjct: 257 SCHVGRLPC----LSFGAITVYSILSLFFIIVMSTHVVRIKQARRSEHLRLLQDTSQCDE 312
Query: 319 PKD-GEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGL 377
D G+++ + ++ NF+ G AAR P + + S + IV +L G
Sbjct: 313 DDDEGDMIHEGDMCNRPYKIYWLNTLFHNFFSRLGYVAARFPGVTILSCVIIVGILSLGC 372
Query: 378 LRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD 437
+ F +E P +LWV P S +A+EK FFD++ PFYR EQ I+ ++ P +++ +
Sbjct: 373 INFEIERDPARLWVSPNSASAKEKAFFDANFGPFYRAEQAILVN--DTGSSGPGPVLSFE 430
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGV 497
++ +++++ +I+ +G +L D+C KP GE C QS+ YF+ + + +
Sbjct: 431 TLQWWINVEKRISKIKGRETG--ATLDDVCFKPTGEACVIQSVSAYFENNISKWTSSTWK 488
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGD 556
++C TS C F P++P LG + + ++ A I T+ + N K
Sbjct: 489 ARLKHCI---TSPVNCLPDFGQPIDPAMILGVVDNSTSLLDSPAIITTWVITNYAEK-ST 544
Query: 557 ENGKAIAWE 565
E KA+ WE
Sbjct: 545 ELTKAMDWE 553
>I3JSF2_ORENI (tr|I3JSF2) Uncharacterized protein OS=Oreochromis niloticus
GN=LOC100695975 PE=4 SV=1
Length = 1273
Score = 215 bits (547), Expect = 5e-53, Method: Compositional matrix adjust.
Identities = 172/591 (29%), Positives = 264/591 (44%), Gaps = 71/591 (12%)
Query: 34 RSIHS-NEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GN--VC 88
RS H +C Y CG+ + GK NC Y P + + LCP GN +C
Sbjct: 25 RSYHVVAHHCVWYGECGESTVAGKKYNCNYTGPPMPLQPDGYQLLTELCPGYDYGNKSLC 84
Query: 89 CTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT 140
C +QL+ + L CPAC N +NLFCEL+CSP+QS F+NVT+I+ VD
Sbjct: 85 CNADQLRTLKGSLQLPLQFLSRCPACFYNLMNLFCELTCSPHQSQFMNVTNITGVD---- 140
Query: 141 VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEW--FAFLGQKVP 195
V ++ Y+ +TF +Y+ACKDV+ + N +A+ + A N W + F +
Sbjct: 141 VRAVEYYIGQTFSNAMYNACKDVQAPSSNVKALSLLCGKTAKECNATNWIQYMFSTKNGQ 200
Query: 196 PGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
FP P D + +PM N + Y+CN++
Sbjct: 201 APFPIEPVFTD--VPLAGYTPM---NNNTYACNESLDDGSGPCSCQDCTKSCGPKPVPPP 255
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
+ + V + L+ Y+ + + FG + S P+L S
Sbjct: 256 LPPPWTILGIDAMAVIMWLS--YMAFLLIFFGVLLGVWCYRKRAITSEYGPILDSNNP-- 311
Query: 316 TNLPKDGEVLVIDPQRQN----EVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
L +G+ DP + N E + L + ++G + R P ++L L +V
Sbjct: 312 --LSLNGD----DPDQVNASCCETLGERFENGLRMLFSSWGSFCVRHPFLILFCCLVLVG 365
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT---LPESEH- 427
GL ++ T P +LW P+S+A +EK++FD H PF+R QLII T L E+
Sbjct: 366 ASAGGLAYMHITTDPVELWSSPKSQARQEKDYFDKHFGPFFRTVQLIITTPLMLNETYDP 425
Query: 428 --GKPP----SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQ 478
G P S++ + + + ++Q +++ + A+Y+ V+L DICL PL ++C
Sbjct: 426 YLGGPSIPFGSVLNKELLHQVLDLQLEIEGLVASYNQESVTLKDICLAPLAPYNDNCTIL 485
Query: 479 SILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLE 522
S+L YFQ D+Y G E H YC S + C F P+
Sbjct: 486 SVLNYFQNSHAALDHYMGDEFYIWADYHDHFLYCVSAPASLNDTTMLHDPCLGTFGGPVF 545
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P ALGG+ NY+ A+A +IT+P+NN L KA+AWE FI+ K
Sbjct: 546 PWLALGGYDDTNYNNATALVITFPINNYLNDTVRLE-KALAWENEFIKFMK 595
>I3JSF3_ORENI (tr|I3JSF3) Uncharacterized protein OS=Oreochromis niloticus
GN=LOC100695975 PE=4 SV=1
Length = 1265
Score = 214 bits (544), Expect = 9e-53, Method: Compositional matrix adjust.
Identities = 170/584 (29%), Positives = 262/584 (44%), Gaps = 70/584 (11%)
Query: 40 EYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GN--VCCTEEQLQ 95
+C Y CG+ + GK NC Y P + + LCP GN +CC +QL+
Sbjct: 24 HHCVWYGECGESTVAGKKYNCNYTGPPMPLQPDGYQLLTELCPGYDYGNKSLCCNADQLR 83
Query: 96 AVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLY 147
+ L CPAC N +NLFCEL+CSP+QS F+NVT+I+ VD V ++ Y
Sbjct: 84 TLKGSLQLPLQFLSRCPACFYNLMNLFCELTCSPHQSQFMNVTNITGVD----VRAVEYY 139
Query: 148 VTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEW--FAFLGQKVPPGFPGSP 202
+ +TF +Y+ACKDV+ + N +A+ + A N W + F + FP P
Sbjct: 140 IGQTFSNAMYNACKDVQAPSSNVKALSLLCGKTAKECNATNWIQYMFSTKNGQAPFPIEP 199
Query: 203 YSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
D + +PM N + Y+CN++ +
Sbjct: 200 VFTD--VPLAGYTPM---NNNTYACNESLDDGSGPCSCQDCTKSCGPKPVPPPLPPPWTI 254
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
+ V + L+ + +L+F FG + S P+L S L +G
Sbjct: 255 LGIDAMAVIMWLSYMAFLLIF--FGVLLGVWCYRKRAITSEYGPILDSNNP----LSLNG 308
Query: 323 EVLVIDPQRQN----EVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
+ DP + N E + L + ++G + R P ++L L +V GL
Sbjct: 309 D----DPDQVNASCCETLGERFENGLRMLFSSWGSFCVRHPFLILFCCLVLVGASAGGLA 364
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT---LPESEH---GKPP- 431
++ T P +LW P+S+A +EK++FD H PF+R QLII T L E+ G P
Sbjct: 365 YMHITTDPVELWSSPKSQARQEKDYFDKHFGPFFRTVQLIITTPLMLNETYDPYLGGPSI 424
Query: 432 ---SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQSILQYFQ 485
S++ + + + ++Q +++ + A+Y+ V+L DICL PL ++C S+L YFQ
Sbjct: 425 PFGSVLNKELLHQVLDLQLEIEGLVASYNQESVTLKDICLAPLAPYNDNCTILSVLNYFQ 484
Query: 486 MDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTTALGG 529
D+Y G E H YC S + C F P+ P ALGG
Sbjct: 485 NSHAALDHYMGDEFYIWADYHDHFLYCVSAPASLNDTTMLHDPCLGTFGGPVFPWLALGG 544
Query: 530 FSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+ NY+ A+A +IT+P+NN L KA+AWE FI+ K
Sbjct: 545 YDDTNYNNATALVITFPINNYLNDTVRLE-KALAWENEFIKFMK 587
>D5GC63_TUBMM (tr|D5GC63) Whole genome shotgun sequence assembly, scaffold_204,
strain Mel28 OS=Tuber melanosporum (strain Mel28)
GN=GSTUM_00000601001 PE=4 SV=1
Length = 1237
Score = 212 bits (540), Expect = 3e-52, Method: Compositional matrix adjust.
Identities = 160/557 (28%), Positives = 257/557 (46%), Gaps = 63/557 (11%)
Query: 26 SLTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT-- 82
S T+ ++ R + CA+ CG++S G L C +P+ +P ++ +C
Sbjct: 4 SCTSTRVYRELAG--VCALRGQCGKKSLFGAQLPCLDNTPATEPSSETRKRLVEICGDDW 61
Query: 83 ITGNVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
G VCC ++QL +A ++ CPAC NF +LFC +CSP+QSLF+NVT+
Sbjct: 62 KEGLVCCGDDQLGDLSKNLKRAESLIASCPACKANFFDLFCTFTCSPDQSLFLNVTATQT 121
Query: 135 VD-GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQK 193
G V +D V+ ++G G + +CKDVKF N A+D +G GA +Y + FLG +
Sbjct: 122 ASTGKEIVTELDYLVSPSYGSGFFDSCKDVKFSGTNGYAMDLIGGGAKDYPAFLKFLGDE 181
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
P GSP+ I+F + M+ M+ S CND+ +
Sbjct: 182 KP---FGSPFQINFPPGGRLDASMKAMDHSPKRCNDSDVA---YRCSCVDCPAVCPTLQE 235
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
K+G V C+ ++ ++Y + +F+L G G +A +
Sbjct: 236 VEVGEECKVGV--VPCLSFAVILIYSISLFILVG-------------GYTAAGI------ 274
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
+ +L K +N QY F+ L + + G A P + + SS IV LL
Sbjct: 275 -YQHLKK-----------RNSEQY-FLNSRLDDLFSWLGHSCASFPAVTISSSAIIVGLL 321
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
G LRF++ET P +LWV P S+AA EK+FFD PFYR +Q + +E G P +
Sbjct: 322 SLGWLRFSIETDPVRLWVSPTSEAALEKKFFDDSFDPFYRAQQAFLVN-DTTEAGASP-V 379
Query: 434 VTDDNIELLFEIQEKVDEIRA-NYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
++ + + F+++ ++ +++ NY V+L D+CLKP C QS+ YF N
Sbjct: 380 LSYEVLSWWFDVENRIRRLKSLNYG---VTLDDVCLKPTDAGCVVQSVAGYFGNSFWNVK 436
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNNAL 551
C ++ C F PL LGG+ + ++ A I+T+ +NN
Sbjct: 437 EGTWQRELRSCAAQPVQSQ-CLPDFGQPLNKDLILGGWQDTGDVLDSRAMIVTWVLNNH- 494
Query: 552 TKVGDENGKAIAWEKAF 568
+ E K + WE++
Sbjct: 495 AEGSKELVKTMDWEQSL 511
>G2YSF6_BOTF4 (tr|G2YSF6) Similar to patched sphingolipid transporter (Ncr1)
OS=Botryotinia fuckeliana (strain T4)
GN=BofuT4_P126020.1 PE=4 SV=1
Length = 1280
Score = 212 bits (539), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 166/558 (29%), Positives = 249/558 (44%), Gaps = 52/558 (9%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLC--PTITGNVCCTEEQ 93
H C++ CG+ S G L CP + +P K+ LC TG VCC Q
Sbjct: 25 HEAGRCSIRGSCGKDSWFGPELPCPDNELAKEPDQEARQKLVELCGPKWSTGPVCCEGSQ 84
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV----DGNMTV 141
+ A+ PI+ CPAC NF N FC +CSP+QSLF+NVT Q+ D V
Sbjct: 85 IDALADQIKKANPIISSCPACKENFYNTFCTFTCSPDQSLFLNVTERKQMGDKKDNKYIV 144
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGS 201
+D ++E +G G + +CKDVKFG N+ A++F+G GA NY + AFLG K GS
Sbjct: 145 TELDQLISEDYGSGFFDSCKDVKFGPTNSNAMEFIGGGAKNYSSFLAFLGHK---SLLGS 201
Query: 202 PYSIDFKTTILDSSPMELMNASVY---SCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
P+ I++ P E MN CND
Sbjct: 202 PFQINYPDP--SKYPEEGMNPLSMVPKKCNDEDPNFRCSCVDCPAVCPALPEVS------ 253
Query: 259 XIKMGSLKVRCVD-LSLAVLYIV-LVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
K GS V + LS A ++ +V +L E L + E + +
Sbjct: 254 --KSGSCHVGLLPCLSFAAIFTYSMVLLLIAVAVFGHIAWAKHTKRRNERLRLLEDVAPS 311
Query: 317 NLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
+ +G+++ + +I + G AAR P I + +S+ IV +L G
Sbjct: 312 DDDDEGDIVHGGAMYDRPQRTYWINTVCDTAFSRLGFTAARFPAITIVTSIIIVGILSLG 371
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
+F +E P +LWV P S AA+EK +FDS+ PFYR EQ+ + ++ P +++
Sbjct: 372 WTKFEIEQNPARLWVSPSSSAAQEKAYFDSNFGPFYRAEQIFLVN--DTNPSGPGPVMSY 429
Query: 437 DNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGG 496
D ++ FE ++++ + +G SD+CLKPLG+ C QS+ Y D+ + G
Sbjct: 430 DTLKWWFEAEDRIRGLTGKQTG--TKFSDVCLKPLGDACVVQSVGGYLN---DDISSVGP 484
Query: 497 VEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKVG 555
+ S C AF PL+P GG+ + +A+A IIT+ VNN
Sbjct: 485 DTWEKTIRSCAESPVNCRPAFGQPLDPKMIFGGWQESGDVIDATALIITWVVNN------ 538
Query: 556 DENG-----KAIAWEKAF 568
D+ G A+ WE +
Sbjct: 539 DDEGSSQVEHAMDWEASL 556
>G1K8E5_ANOCA (tr|G1K8E5) Uncharacterized protein (Fragment) OS=Anolis
carolinensis GN=LOC100561824 PE=4 SV=1
Length = 1282
Score = 211 bits (538), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 173/618 (27%), Positives = 265/618 (42%), Gaps = 93/618 (15%)
Query: 22 WFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVK-PHDLLSAKIQSLC 80
WF L + + ++ C Y CG S K NC Y P+V P D +Q LC
Sbjct: 5 WFLLGLRETPLCHAEVFSDSCVWYGECGIASGDKRYNCEYNGPAVPLPKDGYDL-VQELC 63
Query: 81 PTIT-GNV--CCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINV 129
P + GNV CC QLQ + L CP+C N +NLFCEL+CSP+QS F+N
Sbjct: 64 PGLFFGNVSLCCDVHQLQTLKNNLELPLQFLSRCPSCFYNLINLFCELTCSPHQSEFLNA 123
Query: 130 TSISQV------DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGAN-- 181
T ++ + Y+ ETF +Y+ACKDV+ + N +A+ + G +
Sbjct: 124 TQTEPYIDPVTKQNKTSITELQYYIGETFSNAMYNACKDVEAPSSNVKALGLL-CGKDPK 182
Query: 182 --NYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXX 239
N W ++ K P + I F + M MN + CN++
Sbjct: 183 DCNATNWIQYMFSKDNGQAPFNIIPI-FSGRMSPIHGMTPMNNATKGCNESMDDATGPCS 241
Query: 240 XXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVF--VLFGWIXXXXXXXX 297
+ L V + ++ +LVF V+FG
Sbjct: 242 CQDCSIVCGPKPEPPSPPAPWLLLGLDAMYVIMWISYTGFLLVFFGVVFG---------- 291
Query: 298 XXXGSSAEPLLVSEGRSFTN--LPKDGEVLVIDPQRQNEVQYSFIQEWLSNF-------Y 348
+ R F + P D + RQ+ + ++ + + F +
Sbjct: 292 ---------VWCYRKRHFVSEYTPIDSNIAYSVHLRQDTGEATWCERFGEKFENALRVTF 342
Query: 349 RAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHL 408
++G + R P V+ SL +V++ C GL+ + T P LW P S+A +EKE+FD+H
Sbjct: 343 TSWGAFCVRNPRPVILFSLVVVVMCCSGLMFMKLTTNPIDLWSAPSSQARKEKEYFDAHF 402
Query: 409 APFYRIEQLIIATLPESEHGKP------PS--------IVTDDNIELLFEIQEKVDEIRA 454
PF+R+EQLII ++ H KP PS +T D + + ++Q+ V+ I A
Sbjct: 403 GPFFRVEQLII----QAPHTKPGIYSPYPSGDDVPFGPPLTKDILHQVLDLQDAVENITA 458
Query: 455 NYSGLLVSLSDICLKPL---GEDCATQSILQYFQMDPDNFDNYGGVE---------HAEY 502
+Y+ + L D+CL PL +C S+L YFQ D+ G + H Y
Sbjct: 459 SYNNETIMLKDVCLIPLSPYNNNCTILSVLNYFQNSHSVLDHSIGDDFYVYADYHSHFLY 518
Query: 503 CFQHYTS-------TETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVG 555
C Q S + C F P+ P +GG+ G+NY+ A+A +IT+PV N
Sbjct: 519 CVQAPASLNDTTLLHDPCLGTFGGPVFPWLVMGGYDGDNYNNATALVITFPVQNYYNDTE 578
Query: 556 DENGKAIAWEKAFIQLAK 573
N KA+AWE+ FI+ K
Sbjct: 579 KLN-KALAWEEEFIKFVK 595
>Q7RWL9_NEUCR (tr|Q7RWL9) Putative uncharacterized protein OS=Neurospora crassa
(strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257
/ FGSC 987) GN=NCU04090 PE=4 SV=1
Length = 1162
Score = 211 bits (538), Expect = 6e-52, Method: Compositional matrix adjust.
Identities = 141/465 (30%), Positives = 218/465 (46%), Gaps = 35/465 (7%)
Query: 113 LFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRA 172
+FC +CSPNQSLF+NVT + G V +D ++E +G G Y++CKDVKFG N+RA
Sbjct: 1 MFCTFTCSPNQSLFVNVTKTIEKKGKELVTELDQLISEEYGTGFYNSCKDVKFGPTNSRA 60
Query: 173 IDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSL 232
+D +G GA NY + FLGQ+ F GSP+ I+F + M+ + CND
Sbjct: 61 MDLIGGGAKNYTQLLKFLGQE---RFGGSPFQINFPVEYAEPD-MKPLPMKPKKCNDED- 115
Query: 233 GXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXX 292
+G+L C+ + + Y V++F+ +
Sbjct: 116 --PNFRCACVDCPEICPTLPDVEQAGSCHVGALP--CLSFASILTYSVILFISIAAVVGH 171
Query: 293 XXXXXXXXGSSAEPLLVSEGRSFTNLPKDGE--------VLVIDPQRQNEVQYSFIQEWL 344
S L+++ P D E V +ID ++ + I W
Sbjct: 172 VAWKRHAKRRSERLRLLTDAA-----PSDDEDEGDLTQNVAMIDRPQKTYI----INTWC 222
Query: 345 SNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFF 404
+ + G AA P I + +S+ I +L G F +E P +LWV P S AAEEK FF
Sbjct: 223 DSAFSKLGYVAATFPAITIVTSILIASILSLGWFHFELEKNPARLWVSPTSPAAEEKAFF 282
Query: 405 DSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLS 464
DSH FYR E++ + +++ P +++ D + ++++ V ++ + G S
Sbjct: 283 DSHFGAFYRAEKVFLVN--DTQPSGPGPVLSRDTLLWWMDVEKSVAALKGSNYG--SSFQ 338
Query: 465 DICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPT 524
D+CLKP G+ C QS+ YFQ DPD+ D C S C A+ PL+P+
Sbjct: 339 DLCLKPTGDACVVQSVAAYFQDDPDSVDPETWQSTLRTC---AASPVECRPAYGQPLDPS 395
Query: 525 TALGGF-SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
LGG+ G N +EASA +T+ + N ++ E +A+ WE A
Sbjct: 396 MILGGYPEGGNVAEASAMTVTWVLINP-SENSPEVDRAMDWEVAL 439
>M7U3J8_BOTFU (tr|M7U3J8) Putative patched sphingolipid transporter protein
OS=Botryotinia fuckeliana BcDW1 GN=BcDW1_10177 PE=4 SV=1
Length = 1278
Score = 211 bits (537), Expect = 6e-52, Method: Compositional matrix adjust.
Identities = 166/558 (29%), Positives = 249/558 (44%), Gaps = 52/558 (9%)
Query: 37 HSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLC--PTITGNVCCTEEQ 93
H C++ CG+ S G L CP + +P K+ LC TG VCC Q
Sbjct: 25 HEAGRCSIRGSCGKDSWFGPELPCPDNELAKEPDQEARQKLVDLCGPKWSTGPVCCEGSQ 84
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV----DGNMTV 141
+ A+ PI+ CPAC NF N FC +CSP+QSLF+NVT Q+ D V
Sbjct: 85 IDALADQIKKANPIISSCPACKENFYNTFCTFTCSPDQSLFLNVTERKQMGDKKDNKYIV 144
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGS 201
+D ++E +G G + +CKDVKFG N+ A++F+G GA NY + AFLG K GS
Sbjct: 145 TELDQLISEDYGSGFFDSCKDVKFGPTNSNAMEFIGGGAKNYSSFLAFLGHK---SLLGS 201
Query: 202 PYSIDFKTTILDSSPMELMNASVY---SCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
P+ I++ P E MN CND
Sbjct: 202 PFQINYPDP--SKYPEEGMNPLSMVPKKCNDEDPNFRCSCVDCPAVCPALPEVS------ 253
Query: 259 XIKMGSLKVRCVD-LSLAVLYIV-LVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
K GS V + LS A ++ +V +L E L + E + +
Sbjct: 254 --KSGSCHVGLLPCLSFAAIFTYSMVLLLIAVAVFGHIAWAKHTKRRNERLRLLEDVAPS 311
Query: 317 NLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
+ +G+++ + +I + G AAR P I + +S+ IV +L G
Sbjct: 312 DDDDEGDMVHGGAMYDRPQRTYWINTVCDTAFSRLGFTAARFPAITIVTSIIIVGILSLG 371
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
+F +E P +LWV P S AA+EK +FDS+ PFYR EQ+ + ++ P +++
Sbjct: 372 WTKFEIEQNPARLWVSPSSSAAQEKAYFDSNFGPFYRAEQIFLVN--DTNPSGPGPVMSY 429
Query: 437 DNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGG 496
D ++ FE ++++ + +G SD+CLKPLG+ C QS+ Y D+ + G
Sbjct: 430 DTLKWWFEAEDRIRGLTGKQTG--TKFSDVCLKPLGDACVVQSVGGYLN---DDISSVGP 484
Query: 497 VEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFS-GNNYSEASAFIITYPVNNALTKVG 555
+ S C AF PL+P GG+ + +A+A IIT+ VNN
Sbjct: 485 DTWEKTIRSCAESPVNCRPAFGQPLDPKMIFGGWQESGDVIDATALIITWVVNN------ 538
Query: 556 DENG-----KAIAWEKAF 568
D+ G A+ WE +
Sbjct: 539 DDEGSSQVEHAMDWEASL 556
>H8X9T5_CANO9 (tr|H8X9T5) Ncr1 h OS=Candida orthopsilosis (strain 90-125)
GN=CORT_0G00620 PE=4 SV=1
Length = 1286
Score = 211 bits (536), Expect = 8e-52, Method: Compositional matrix adjust.
Identities = 156/560 (27%), Positives = 256/560 (45%), Gaps = 57/560 (10%)
Query: 33 SRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTE 91
+RS HS YC +D CG++S GK L C P+ +P ++Q +C VCC+
Sbjct: 18 ARSNHSPGYCNTFDNCGKKSIFGKPLPCVNFVPATEPSKESRDRLQQICGRDFEYVCCSS 77
Query: 92 EQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINV--TSISQVDGNMTV 141
Q+ + I+ CPAC +NF + FCE SCSP++S F+ + T I++ G V
Sbjct: 78 HQIDELESNLKRVDAIISSCPACHKNFYDFFCEFSCSPDESTFVEIVKTEIAKDTGKEIV 137
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGS 201
ID YV+ E + +CK+VKF N A+D +G GA NY ++ FLG + P GS
Sbjct: 138 TEIDQYVSPELAEKFFDSCKEVKFSATNGFAMDLIGGGAKNYSQFLKFLGDE-KPLLGGS 196
Query: 202 PYSIDFKTTI-LDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
PY I+FK + + ++L N +YSC+D
Sbjct: 197 PYQINFKYKLDHEKKGLKLRNDKMYSCSDEEYKCACTDCQSSCPKLPHAKNLSKKCTVGF 256
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
V C S+ ++ + L+ +L G+ E R +
Sbjct: 257 ------VPCFTFSVWMVLVCLILLLGGYHIYLANAK-------------REFRRRGSYED 297
Query: 321 DGEVLVIDPQRQNEVQYSFIQEW-------LSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
+ +I P V+ ++++ + + + ++ + P I + +SL + +LL
Sbjct: 298 ENNDEIISPLNYVTVRKPMVRQFSDKLNSQVQDGFEKLAKFCSTFPGITIGTSLLVSMLL 357
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
G+ + ++ET P LWV P A +++F+S+ ++RIEQ+I++T + P I
Sbjct: 358 SLGMFKLDIETSPINLWVSPTEPAYINQQYFESNFGEWFRIEQVIVST----KSNGP--I 411
Query: 434 VTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDN 493
D IE F+ + K++E+ + +SLSDIC KPLG+ CA +S QYF D +
Sbjct: 412 FNWDTIEWWFDQESKLEELSSK-----ISLSDICFKPLGDACAIESFTQYFHGDLNQLSK 466
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTK 553
+ C S C +F+ PL+P F N EA+AF +T ++N +
Sbjct: 467 ENWARKLQNCVD---SPVNCLPSFQQPLKPALL---FDDPNILEATAFTVTILIDNNSSN 520
Query: 554 VGDENGKAIAWEKAFIQLAK 573
N +++E +F AK
Sbjct: 521 TTLVN-DIVSYEHSFQAWAK 539
>G8BL56_CANPC (tr|G8BL56) Putative uncharacterized protein OS=Candida
parapsilosis (strain CDC 317 / ATCC MYA-4646)
GN=CPAR2_700490 PE=4 SV=1
Length = 1300
Score = 210 bits (535), Expect = 1e-51, Method: Compositional matrix adjust.
Identities = 157/563 (27%), Positives = 259/563 (46%), Gaps = 69/563 (12%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQLQ 95
HS YC YD CG++S GK L C P+ +P ++ +C VCC+ Q+
Sbjct: 61 HSPGYCNTYDNCGKKSIFGKPLPCANFVPATEPSKESRDRLAKICGRDFDYVCCSSSQID 120
Query: 96 AV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINV--TSISQVDGNMTVDGID 145
+ I+ CPAC +NF + FC+ SCSPN+S F+ + T +++ G V ID
Sbjct: 121 ELESNLKRVDAIISSCPACHKNFYDFFCQFSCSPNESTFVEIVKTQVAKDTGKEIVTEID 180
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
YV+ E +++CK+VKF N A D +G GA NY ++ FLG + P GSPY I
Sbjct: 181 QYVSPDLAEKFFNSCKEVKFSATNGFATDLIGGGAKNYSQFLKFLGDE-KPLLGGSPYQI 239
Query: 206 DFKTTI---LDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
+FK + + ++L N ++SC+D +
Sbjct: 240 NFKYELNQGQEKQGLKLRNDEMFSCSDEEYKCACTDCQSSCPKLPHAKNLSKRCTVGL-- 297
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT---NLP 319
V C S+ ++ + LV +L G+ L + R F +
Sbjct: 298 ----VPCFTFSVWMVLVCLVILLGGY----------------HIYLANAKREFKRRGSYE 337
Query: 320 KDGEVLVIDPQRQNEVQYSFIQEW-------LSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
D E +I P V+ ++++ + + + ++ + P + + +SL + +L
Sbjct: 338 DDEEDEIISPLNYVTVRKPVVRQFSDKLNSQVQDGFEKLAKFCSTFPGVTIGTSLVVSLL 397
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
G+L+ N+ET P LWV P A +++F+S+ ++RIEQ+I++T +G+P
Sbjct: 398 FSLGMLKLNIETNPINLWVSPNEPAYINQQYFESNFGEWFRIEQVIVST----ANGEP-- 451
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFD 492
I D IE F+ QE + E + ++ LSDIC KPLG CA +S QYF D +
Sbjct: 452 IFNWDTIEWWFK-QESILENLSPHT----RLSDICFKPLGGACAIESFTQYFDGDINRLS 506
Query: 493 NYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN--A 550
N + C S C F+ PL+P F ++ +A+AF +T ++N +
Sbjct: 507 NDTWARKLQNCAD---SPVNCLPLFQQPLKPALL---FDNSDILKATAFTMTVLIDNNSS 560
Query: 551 LTKVGDENGKAIAWEKAFIQLAK 573
T + D+ +++E +F AK
Sbjct: 561 NTTLVDD---IVSYEHSFQAWAK 580
>M3HR68_CANMA (tr|M3HR68) Uncharacterized protein OS=Candida maltosa Xu316
GN=G210_5008 PE=4 SV=1
Length = 1258
Score = 209 bits (533), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 154/566 (27%), Positives = 258/566 (45%), Gaps = 66/566 (11%)
Query: 33 SRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN------ 86
+ S H YC Y CG++S V P P + +P S + I G+
Sbjct: 19 ASSTHKQGYCNTYGNCGKKS---VFGKPLPCATFEPAHRASQESIDRLKAICGDDVNYEY 75
Query: 87 VCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINV--TSISQVD 136
VCC++EQ+ + P++ CPAC +NF + FC+ SCSPN+S F+ + + +++
Sbjct: 76 VCCSDEQITDLETNLKRVDPLISSCPACRKNFYDFFCKFSCSPNESQFVEIVKSEMAKDT 135
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPP 196
G V I+ +V + + +CK+VKF N A+D +G GA +Y+++ FLG + P
Sbjct: 136 GKEIVTEINQFVDPAMAKSFFDSCKNVKFSATNGYAMDLIGGGAKDYQQFLKFLGDE-KP 194
Query: 197 GFPGSPYSIDFKTTIL---DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
GSPY I+FK I S+ + L + + +C+D
Sbjct: 195 LLGGSPYQINFKYDISKENQSAGLVLRDDGMKTCDDKDY----KCACTDCEASCPKLPHA 250
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++G L C ++ V++ + +L G+ GR
Sbjct: 251 RDLTEKCRVGVLP--CFSFTVIVIWSCFIILLGGYHVYLAKAK-------------KNGR 295
Query: 314 SFTNLPKDGEVLVIDPQRQ---NEVQYSFIQEWLSNF----YRAYGRWAARRPTIVLCSS 366
+ + +V+DP R + + E LS + + G++ + P + + S
Sbjct: 296 ISLMDDDEDDDIVMDPNRYVGLGKHSAKKVSETLSVHIEYAFESIGKFCSHFPGVSIGGS 355
Query: 367 LAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESE 426
L + +LL GL + +ET P KLWV P +A + ++FF+S+ ++RIEQ+I+++ SE
Sbjct: 356 LTVAVLLSLGLFKLKLETDPVKLWVSPRDEAYKNQQFFESNFGEWFRIEQVIVSSQNTSE 415
Query: 427 HGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQM 486
++ D + FE + +++ + N VSLSDIC KPL E CA QS QYFQ
Sbjct: 416 -----PVLNWDVFKWWFESESQLETLNKN-----VSLSDICFKPLDETCAIQSFTQYFQG 465
Query: 487 DPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYP 546
D + + C S C +F+ PL+P F N+ S+A AF +T
Sbjct: 466 DLTGLNENNWKSKLQNCVD---SPVNCLPSFQQPLKPNIL---FDNNDISKAKAFTVTVL 519
Query: 547 VNNALTKVGDENGKAIAWEKAFIQLA 572
+N+ ++ IA+E +F + A
Sbjct: 520 INSD-SQDKQYTESVIAYEHSFQKWA 544
>F7CFS9_XENTR (tr|F7CFS9) Uncharacterized protein (Fragment) OS=Xenopus
tropicalis GN=npc1 PE=4 SV=1
Length = 1280
Score = 209 bits (533), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 174/604 (28%), Positives = 263/604 (43%), Gaps = 97/604 (16%)
Query: 38 SNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI---TGNVCCTEEQ 93
S+++C Y CG + + K LNC Y P + + +Q LCP++ VCC +Q
Sbjct: 21 SSQHCVWYGECGNSTLEDKRLNCRYSGPPISLPEEGHTLLQQLCPSLYYGNNTVCCDVQQ 80
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDG------NM 139
L + L CP+C NF+ +FCEL+CSP QS F+NVT G N
Sbjct: 81 LNTLNSNLQLPLQFLSRCPSCFYNFMTMFCELTCSPYQSEFLNVTQTEPFVGPSPQRANE 140
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAI------DFVGAGANNYKEW-FAFLGQ 192
++ ++ Y+ E F +Y+ACKDV+ + N +A+ D A N+ ++ F+
Sbjct: 141 SIVAMEYYIGEQFANAMYNACKDVEAPSSNVKALALLCGKDVKDCNATNWIQYMFSKDNG 200
Query: 193 KVPPGFPGSP-YSIDFKTTILD--------SSPMELMNASVYSCNDTSLGXXXXXXXXXX 243
+VP F +P +S D T++L P+E AS SC D +L
Sbjct: 201 QVP--FTITPIFSDDPVTSMLPMNNATKGCDEPVEEGGASC-SCQDCALSCGPVPQPPPL 257
Query: 244 XXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSS 303
+ + + + ++Y+V + + I S
Sbjct: 258 PPPWLI---------------FGLDAMAVIMWIVYVVFLLLFSAVIIGSWCYRKKNIVSE 302
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYR----AYGRWAARRP 359
P+ + S + P GE D + E L NF R +G + R+P
Sbjct: 303 YAPIDSTLAYSVNSTPIAGEPSCCDR----------LGERLENFLRIGFTKWGSFCVRKP 352
Query: 360 TIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII 419
IV+ S+ ++++ CFGL + T P +LW P S+A +EKE+FDSH PF+R EQLII
Sbjct: 353 WIVIFFSVLLIVICCFGLKYMRITTDPVELWSDPHSQARQEKEYFDSHFGPFFRTEQLII 412
Query: 420 ATLPESEHGKPPSIVTDD---------NI-ELLFEIQEKVDEIRANYSGLLVSLSDICLK 469
S H P D NI + E+Q ++ ++A Y+ V L DICL
Sbjct: 413 TAPNSSVHNYSPYPSGSDVPFGPPLDFNILAQVLELQNGIENLKAYYNNETVMLKDICLA 472
Query: 470 PLG---EDCATQSILQYFQMD--------PDNFDNYGGVE-HAEYCFQHYTST------- 510
PL +C S+L YFQ D+F Y H YC + S
Sbjct: 473 PLAPYNNNCTIFSVLNYFQNSFSVLNHSIQDDFYVYADYHTHFLYCVRSPASLNDTSVLH 532
Query: 511 ETCFSAFKAPLEPTTALGGFSGN-NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFI 569
+ C F P+ P LGG+ + NY+ A+A +IT+PVNN N +A AWE FI
Sbjct: 533 DPCLGTFGGPIFPWLVLGGYDADENYNNATALVITFPVNNFRNDTEKLN-RAKAWELEFI 591
Query: 570 QLAK 573
+ +
Sbjct: 592 KFVE 595
>J4G101_FIBRA (tr|J4G101) Uncharacterized protein OS=Fibroporia radiculosa
(strain TFFH 294) GN=FIBRA_01461 PE=4 SV=1
Length = 1419
Score = 209 bits (533), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 171/606 (28%), Positives = 256/606 (42%), Gaps = 96/606 (15%)
Query: 41 YCAMYDICGQRS-DGKVLNCPYPSP----SVKPHDLLSAKIQ--------------SLCP 81
YC+M CG + GK L CPY P SV H L K+ SLC
Sbjct: 17 YCSMRGSCGSKGWFGKPLPCPYDGPASDVSVSVHSLYLLKLSVTFTQEDVDRDLLVSLCG 76
Query: 82 T--ITGNVCCTEEQLQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTS 131
G CCT +QL+ A I+ CPAC NF +C +CSPNQ F+NVTS
Sbjct: 77 ADYAEGPTCCTTDQLETMRDNLGLAENIISSCPACRNNFRQFWCSFTCSPNQGTFLNVTS 136
Query: 132 I--SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAF 189
S+ D V +D YV+E FGEG Y +CK +K G+ N A+D +G GA +Y + F
Sbjct: 137 TQTSRTD-QEAVQSVDFYVSERFGEGFYDSCKSIKMGSTNGYAMDLIGGGAKDYSAFLKF 195
Query: 190 LGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
+G + GSP+ +++ ++ M + + +C D L
Sbjct: 196 MGDEKD---IGSPFQVNYPASL--PPEMSYFDVTPRNCADNDLSSRCTCIDCPDVCQTLP 250
Query: 250 XXXXXXXXXXIKMGSLKVRCVDLSLAVLY-IVLVFVLFGWIXXXXXXXXXXXGSSAEPLL 308
+G L C+ L ++Y + ++ LFG++ A L
Sbjct: 251 YIPPPNLAPTCHVGMLT--CLSFVLVIVYSLAVISFLFGYVLQLSIRKRKSYERVA--LN 306
Query: 309 VSEGRSFTNLPK----------------DGE---------------VLVIDP-QRQNEVQ 336
V P+ DGE ++DP + Q
Sbjct: 307 VDTTSEHVTSPRVNGRGLVGASSLAQHVDGEESTGTQSESRNLGRGASLLDPIETVQPRQ 366
Query: 337 YSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESK 396
Y FYR G AA P + AIV LL G +F VET P +LWV P S+
Sbjct: 367 YRLNNVLRRAFYR-LGFVAATYPWLTFAIVFAIVGLLNLGWKKFEVETDPVRLWVAPNSE 425
Query: 397 AAEEKEFFDSHLAPFYRIEQLIIA--------TLPESEHGKPPSIVTDDNIELLFEIQEK 448
+ +KEFFD H PFYR EQ+ + + E K +++ + ++ F+++
Sbjct: 426 SKLQKEFFDEHFGPFYRAEQIFVTSSQIGSSDSSAELSVYKTEPVLSWERLKYWFDVEAD 485
Query: 449 VDEIRANYSGLLVSLSDICLKPLGED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQH 506
+ +R++ +G +L D+C KP G D C QS +F D + +D H C
Sbjct: 486 IRGLRSSPNGY--TLDDVCFKPAGPDGFCVVQSATAWFGNDLEMYDRDTWASHLVDC--- 540
Query: 507 YTSTETCFSAFKAPLEPTTALGGFSGNN----YSEASAFIITYPVNNALTKVGDENGKAI 562
TS C F+ PL P LGG + + +A A ++T+ V+++L +E +A+
Sbjct: 541 ATSPVECLPDFQQPLAPQYVLGGVPQTDVPSRFLDAEALVVTFVVSDSLD--AEEQERAM 598
Query: 563 AWEKAF 568
WE+A
Sbjct: 599 EWERAL 604
>F6N6I8_DANRE (tr|F6N6I8) Niemann-Pick disease type C1 protein OS=Danio rerio
GN=six6b PE=2 SV=1
Length = 1277
Score = 209 bits (532), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 170/597 (28%), Positives = 261/597 (43%), Gaps = 58/597 (9%)
Query: 23 FSPSLTAAQISRSIHSNEYCAMYDICGQRSD--GKVLNCPYPSPSVKPHDLLSAKIQSLC 80
F L +S +H ++C Y CG + K LNC Y P+V + +Q LC
Sbjct: 10 FRLLLATVLLSHWVH-GQHCIWYGECGNSPNVPEKKLNCNYTGPAVPLPNEGQELLQELC 68
Query: 81 PTIT---GNVCCTEEQLQA------VPI--LVGCPACLRNFLNLFCELSCSPNQSLFINV 129
P + VCC +QL +P+ L CPAC NF+ LFCEL+CSP QS FI+V
Sbjct: 69 PRLVYADNRVCCDTQQLNTLKSNIQIPLQYLSRCPACFFNFMTLFCELTCSPRQSQFISV 128
Query: 130 TSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEW 186
+ +V + Y+T+TF + +++AC+DV+ + N +A+ + A + W
Sbjct: 129 KDFLKEKNLTSVGNVTYYITQTFADAMFNACRDVQAPSSNIKALGLLCGRDASVCTPQIW 188
Query: 187 FAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDT-SLGXXXXXXXXXXXX 245
++ + G P+ I+ T + M MN ++C+ + G
Sbjct: 189 IQYMF-SISNG--QVPFGIEPIFTDVPVQGMTPMNNRTFNCSQSLDDGSEPCSCQDCSEV 245
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAE 305
I +G + + + YI + + FG +
Sbjct: 246 CGPTPVPPPIPPPWIILG---LDAMSFIMWCSYIAFLLIFFGVVLGAWCYRRSVVTXEYG 302
Query: 306 PLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCS 365
P+L S +L DG L ID E + L + +G R+P ++ S
Sbjct: 303 PILDSNQPH--SLNSDGTDL-IDEASCCETVGERFENSLRLVFSRWGSLCVRQPLTIILS 359
Query: 366 SLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
SL ++ + GL + T P +LW P S+A +EK FD H PF+R EQLII T P +
Sbjct: 360 SLVLICICSAGLSYMRITTNPVELWSAPSSRARQEKNCFDQHFGPFFRTEQLIITT-PWT 418
Query: 426 EHGKPPSIVTDD-------NIELL---FEIQEKVDEIRANYSGLLVSLSDICLKPL---G 472
E G +I D N+ LL ++Q +++ + A Y G V+L DIC+ PL
Sbjct: 419 EEGGFSTITGDIIPFSPILNLSLLHQVLDLQLEIENLIAEYKGENVTLKDICVSPLSPYN 478
Query: 473 EDCATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTSTET-------CFSA 516
++C S+L YFQ + D+ E H YC TS + C
Sbjct: 479 DNCTILSVLNYFQNSHEVLDHEFQDEFFLYNDYHTHLLYCASSPTSLDDTSRLHDPCMGT 538
Query: 517 FKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
F P+ P LGG+ + Y+ A+A T+PV N L ++ GKA+AWEK FI+ K
Sbjct: 539 FGGPVFPWLVLGGYEDSAYNNATALFFTFPVTNCLNDT-EKLGKALAWEKEFIRFMK 594
>H0XBD5_OTOGA (tr|H0XBD5) Uncharacterized protein OS=Otolemur garnettii GN=NPC1
PE=4 SV=1
Length = 1278
Score = 209 bits (532), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 170/589 (28%), Positives = 251/589 (42%), Gaps = 68/589 (11%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPY-----PSPSVKPHDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG S K NC Y P P P + S + + LCP ++CC
Sbjct: 22 SQSCVWYGECGIASGDKRYNCKYSGPPKPLPKDGPMSVFSHQ-KELCPGFFFDNVSLCCD 80
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 81 VQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 140
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + Y+ +TF +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 141 TRTNVKELQYYIGQTFANAMYNACRDVQAPSSNEKALGLLCGKDAAACNATNWIEYMFNK 200
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + CN++
Sbjct: 201 ---DNGQAPFTITPVFSDLPAHGMEPMNNATKGCNESVDEVTGPCSCQDCSATCGPKPQP 257
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + + Y+ + V FG S P+ S
Sbjct: 258 PPPPVPWRLFGLDAMYV--IMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSSIAF 315
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + + +G + R P V+ SL +
Sbjct: 316 S-VNGSDKGEASCCDP-----VGAAF-EGCLRHLFTRWGSFCVRNPGCVIFFSLVFITTC 368
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII + H P
Sbjct: 369 SSGLVFIRVTTNPVDLWSAPRSQARLEKEYFDQHFGPFFRTEQLIIRAPLTNTHTYEPYP 428
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D N+E+L ++ Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 429 SGADVPFGPPLNVEILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSV 488
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 489 LNYFQNSHSVLDHKIGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 548
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 549 LVLGGYDDENYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFIDFVK 596
>K1VIA0_TRIAC (tr|K1VIA0) Vacuolar membrane protein OS=Trichosporon asahii var.
asahii (strain CBS 8904) GN=A1Q2_05191 PE=4 SV=1
Length = 1328
Score = 207 bits (528), Expect = 7e-51, Method: Compositional matrix adjust.
Identities = 160/565 (28%), Positives = 251/565 (44%), Gaps = 72/565 (12%)
Query: 41 YCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT---ITGNVCCTEEQLQA 96
YCAM CG+ + G L CP + K +S ++ +C + I +VCCT +Q+QA
Sbjct: 31 YCAMRGNCGRATMFGAELPCPDDGKADKISPDISKLLKQVCGSSYEIPSHVCCTVDQVQA 90
Query: 97 V--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGIDLY 147
+ P++ CPAC+ NF + +C+ +CSP+Q+ F+ VT + +G V +D
Sbjct: 91 LGDQLSQAAPLIASCPACINNFRSFYCDFTCSPDQAQFLKVTQTQKTTEGKDAVKSVDYG 150
Query: 148 VTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDF 207
V+ F EG + +CK V+FG N A+D +G GA N + ++G + PG GSP+ I+F
Sbjct: 151 VSSNFAEGFFDSCKSVQFGATNGFAMDLIGGGAKNASAFLKYMGDE-RPGL-GSPFQINF 208
Query: 208 KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
P + N + +G+ V
Sbjct: 209 --------PFDAGEYQREPLNCADVNNQNAHCACVDCPDVCPALPSPPSHGQCTVGA--V 258
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXG----SSAEPL---------LVSEGRS 314
C+ SL ++Y VL+ W+ S PL LV G
Sbjct: 259 SCLTFSLLIIYSVLLLAGIIWLAARSFWSRRKASYERVSLDAPLSPTISGLDGLVGRGDD 318
Query: 315 FTNLPKDGEVL--------VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+ P G V ++DP + + + I L F+ G A+RP
Sbjct: 319 SESGPS-GSVHFRLGRGASLLDPMEHMQPKQNAINAALRRFFYRLGLVCAKRPIATFAIW 377
Query: 367 LAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESE 426
I+ L G F+VET P +LWV P S+AA++KEFFD PF+R EQL ++
Sbjct: 378 AVIIAALNVGWKDFSVETDPVRLWVSPSSEAAQQKEFFDKEFGPFFRSEQLFVS------ 431
Query: 427 HGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQY--F 484
H +++ D I+ + +++++++ NY G +L +C P G+ C QSI + +
Sbjct: 432 HKDGSTVMDRDTIQWWLDTEDQINKL--NYQG--STLEKVCFAPGGDACVVQSISAWTGY 487
Query: 485 QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIIT 544
++D D + + C +H C F PL+P LGG G N+ ASA +IT
Sbjct: 488 ELDDD------WAKRIDQCAKH---PAECLPDFGQPLDPKLVLGGAEG-NWLNASALVIT 537
Query: 545 YPVNNALTKVGDENGKAI-AWEKAF 568
Y VNN + GD+ K WE+
Sbjct: 538 YVVNN--YEEGDKRLKMPEKWERGL 560
>G3PZ00_GASAC (tr|G3PZ00) Uncharacterized protein (Fragment) OS=Gasterosteus
aculeatus GN=NPC1 PE=4 SV=1
Length = 1264
Score = 207 bits (528), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 167/590 (28%), Positives = 252/590 (42%), Gaps = 82/590 (13%)
Query: 40 EYCAMYDICGQ-RSDGKVLNCPYPSP----SVKPHDLLSAKIQSLCPTIT---GNVCCTE 91
++C Y CG + GK NC Y P + H+LL+ LCP ++CC
Sbjct: 23 QHCVWYGECGDSKIAGKKYNCNYTGPPKPLQAEGHELLA----ELCPGYDYGDRSLCCDV 78
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDG 143
+QL ++ L CPAC NF+NLFCEL+CSP+QS F+N T + +V
Sbjct: 79 DQLNSLKGSLQLPLQFLSRCPACSSNFMNLFCELTCSPHQSRFMNSTDFN----GPSVTE 134
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFL-----GQKVP 195
+ Y+ +TF +Y+ACKDV+ + N +A+ + G A N W ++ GQ
Sbjct: 135 VQYYIGQTFTNAMYNACKDVQAPSSNVKALSLLCGKDAKDCNATNWIQYMFNINNGQ--- 191
Query: 196 PGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXX 252
SP+ I + + S MN Y+C D G
Sbjct: 192 -----SPFPIIPIFSDVPVSGYTPMNNKTYACTEGLDDGSGPCSCQDCTKACGPKPVPPP 246
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
+ ++ V + + Y + + FG + S P+L S
Sbjct: 247 VPPPWTIFGIDAMTV-----IMWISYSAFLLIFFGAVLGVWYYRKRTIMSEYGPILDSNN 301
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
N +V + E + L + ++G + R P++VL SL +V+
Sbjct: 302 PLSLNADNPDQVNASCCETLGER----FENALRTLFSSWGSFCVRHPSVVLLGSLILVVG 357
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP- 431
GL+ + T P +LW P S+A +EK+FFDSH PF+R QLII T P
Sbjct: 358 SSGGLVYMRITTDPVELWSSPSSQARQEKDFFDSHFGPFFRTAQLIITTPIVDPFLYSPY 417
Query: 432 ---------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQS 479
+I+ D + + ++Q ++ + A Y G V+L DICL PL +C S
Sbjct: 418 FGGSDVPFGAILRKDILHQVLDLQLDIESLTATYEGQTVTLKDICLAPLAPYNTNCTILS 477
Query: 480 ILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEP 523
+L YFQ D D+ G + H YC S + C + P+ P
Sbjct: 478 VLNYFQNSHDVLDHSAGDDFFVYADYHSHFLYCVSAPASLNDTTLLHDPCLGTYGGPIFP 537
Query: 524 TTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
ALGG+ NY+ A+A ++T+PVNN L GKA AWEK F++ K
Sbjct: 538 WLALGGYDETNYNNATALVVTFPVNNYLND-SVRLGKARAWEKEFVKFMK 586
>Q9JLG3_CRIGR (tr|Q9JLG3) Niemann-Pick type C1 protein OS=Cricetulus griseus
GN=NPC1 PE=2 SV=1
Length = 1277
Score = 206 bits (523), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 173/595 (29%), Positives = 254/595 (42%), Gaps = 84/595 (14%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DLL Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAFGDKKYNCKYSGPP-KPLPKDGNDLL----QELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QLQ + L CP+C N + LFCEL+CSP+QS F+NVT+ +
Sbjct: 77 VQQLQTLKSNLQLPMQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYVDPKTQE 136
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ Y+ ++F +Y+AC+DV+ N +A+ + A A N W ++ K
Sbjct: 137 NKTNVKELEYYIGQSFANEMYNACRDVEAPASNEKALGILCGKDASACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSP---MELMNASVYSCN---DTSLGXXXXXXXXXXXXXX 247
+P++I T I P ME M + CN D G
Sbjct: 197 ---NNGQAPFTI---TPIFSDLPILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPK 250
Query: 248 XXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPL 307
+ + ++ V + V Y+ +F+ FG + S P+
Sbjct: 251 PQPPPTPVPWRILGLDAMYV-----IMWVTYMAFLFIFFGGLLAVWCHRRRYFVSEYTPI 305
Query: 308 LVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
+ S +N GE DP + + L + +G + R PT V+ SL
Sbjct: 306 DSNIAFS-SNTSDKGEASCCDPLG------AAFDDCLRRMFTKWGAFCVRNPTCVIFFSL 358
Query: 368 AIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH 427
+ GL+ V T P +LW P S+A EKE+FD H PF+R+EQLII SEH
Sbjct: 359 VFITACSSGLVFVRVTTNPVELWSAPHSRARLEKEYFDKHFGPFFRMEQLIIQAPNTSEH 418
Query: 428 GKPPSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GED 474
P D N E+L ++ Q ++ I +Y+ V+L DIC+ PL ++
Sbjct: 419 IYEPYPSGSDVSFGPPLNKEILHQVLDLQIAIESITTSYNNKTVTLQDICVAPLSPYNKN 478
Query: 475 CATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFK 518
C S+L YFQ D+ G + H YC + TS + C F
Sbjct: 479 CTIISVLNYFQNSHSVLDHQVGDDFYVYADYHTHFLYCVRAPTSLNDTSLLHDPCLGTFG 538
Query: 519 APLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P+ P LGG+ NY+ A+A +IT+PV+N ++ +A AWEK FI K
Sbjct: 539 GPVFPWLVLGGYDDQNYNNATALVITFPVSNYYNDT-EKLQRAQAWEKEFIDFVK 592
>G3J3M1_CORMM (tr|G3J3M1) Niemann-Pick C1 protein OS=Cordyceps militaris (strain
CM01) GN=CCM_00351 PE=4 SV=1
Length = 1353
Score = 205 bits (522), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 151/540 (27%), Positives = 242/540 (44%), Gaps = 31/540 (5%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPT--ITGNVCCTEEQ 93
H CA CG++S GK L C + P L +++ LC G VCCT Q
Sbjct: 113 HEQGRCAFRGQCGKQSFFGKELPCVENGLAQDPEAELRSELVDLCGEEFREGPVCCTLPQ 172
Query: 94 LQAVPILVG--------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGID 145
+QA+ +G CPAC NF N FC+ +CSP+QSLF+NVTS ++ + V +D
Sbjct: 173 VQALKSELGTPNTLIGSCPACKHNFFNTFCKFTCSPDQSLFVNVTSAAEKGDQLLVTELD 232
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
++ +G G Y +CK+VKFG N+RA++ +G GA Y + FLG K GSP+ I
Sbjct: 233 HLISNEYGAGFYDSCKEVKFGGANSRAMNLIGGGAKEYTAFLKFLGDK---KLVGSPFQI 289
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F T D M ++ CND ++G+L
Sbjct: 290 NFPRT-YDDPAMGPLDMKAKKCNDED---PNYRCVCVDCPEVCPDLPEVKQNHSCRVGAL 345
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
C+ + +Y +L+F L + + L+ E S ++ +G +
Sbjct: 346 P--CLSFASIFIYSILLFALAALLSGHVVWKKFSKRRAERTRLLHEA-SHSDDEDEGGPV 402
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
+ R V+ ++ + + G AA P + + L +V +L G + F++E
Sbjct: 403 QSEAMRDRPVKRYWLNDRCDKAFYQLGLSAANAPALTITICLVVVAILSAGWVHFDLEKE 462
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEI 445
P +LWV P S AA+EK +FD + PFYR EQ + ++ P +++ + ++ +
Sbjct: 463 PARLWVSPSSAAAQEKAYFDDNFGPFYRAEQAFLVN--DTLSDGPSPVLSYETLQWWIGV 520
Query: 446 QEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
+ + + + G L D+C KP + C QS+ Y+Q F + C +
Sbjct: 521 ERSIQNLESPTYGKY--LRDLCFKPTNDACVIQSVSAYWQ-SKGGFGRKTWQDELRACAK 577
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
S C F P+EP LGG+ ++ + A A +T+ VNNA E A+ WE
Sbjct: 578 ---SPVECRPDFGQPIEPEMILGGYD-SDVAHAKAITVTWVVNNAPGGT-IEFAHAVDWE 632
>Q3U2B2_MOUSE (tr|Q3U2B2) Putative uncharacterized protein OS=Mus musculus
GN=Npc1 PE=2 SV=1
Length = 1094
Score = 205 bits (522), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 253/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG + K NC Y P KP +DL +Q LCP + ++CC
Sbjct: 22 SQSCVWYGECGIATGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGLFFDNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QLQ + L CP+C N + LFCEL+CSP+QS F+NVT+ +
Sbjct: 77 IQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQE 136
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ +V ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 NKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L ME M + CN++
Sbjct: 197 ---DNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQP 253
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + V Y+ +FV FG + S P+ +
Sbjct: 254 PPPPMPWRIWGLDAMYV--IMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP + + L + +G + R PT ++ SLA + +
Sbjct: 312 S-VNSSDKGEASCCDPLG------AAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P +LW P S+A EKE+FD H PF+R EQLII S H P
Sbjct: 365 SSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D N E+L ++ Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 AGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSV 484
Query: 481 LQYFQ-----MDP---DNFDNYGGVE-HAEYCFQHYTSTET-------CFSAFKAPLEPT 524
L YFQ +D D+F Y H YC + S C F P+ P
Sbjct: 485 LNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQRAWAWEKEFISFVK 592
>Q7TMD4_MOUSE (tr|Q7TMD4) Niemann Pick type C1 OS=Mus musculus GN=Npc1 PE=2 SV=1
Length = 1277
Score = 205 bits (521), Expect = 5e-50, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 253/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG + K NC Y P KP +DL +Q LCP + ++CC
Sbjct: 22 SQSCVWYGECGIATGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGLFFDNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QLQ + L CP+C N + LFCEL+CSP+QS F+NVT+ +
Sbjct: 77 IQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQE 136
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ +V ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 NKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L ME M + CN++
Sbjct: 197 ---DNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQP 253
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + V Y+ +FV FG + S P+ +
Sbjct: 254 PPPPMPWRIWGLDAMYV--IMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP + + L + +G + R PT ++ SLA + +
Sbjct: 312 S-VNSSDKGEASCCDPLG------AAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P +LW P S+A EKE+FD H PF+R EQLII S H P
Sbjct: 365 SSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D N E+L ++ Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 AGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSV 484
Query: 481 LQYFQ-----MDP---DNFDNYGGVE-HAEYCFQHYTSTET-------CFSAFKAPLEPT 524
L YFQ +D D+F Y H YC + S C F P+ P
Sbjct: 485 LNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQRAWAWEKEFISFVK 592
>L9JF67_TUPCH (tr|L9JF67) Niemann-Pick C1 protein OS=Tupaia chinensis
GN=TREES_T100006800 PE=4 SV=1
Length = 1420
Score = 204 bits (520), Expect = 6e-50, Method: Compositional matrix adjust.
Identities = 166/589 (28%), Positives = 250/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG + K NC Y P KP +DL +Q LCP ++CC
Sbjct: 240 SQSCVWYGECGIATGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCD 294
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 295 VQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 354
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V+ + YV ++F +Y+AC+DV+ + N +A+ F+ A A N W ++ K
Sbjct: 355 TKTNVEELQYYVGQSFANAMYNACRDVEAPSSNDKALGFLCGKDADACNATNWIEYMFSK 414
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L ME MN + +C+++
Sbjct: 415 ---DNGQAPFTITPIFSDLPVHGMEPMNNATKACSESVDEVTGPCSCQDCSVMCGPKPQP 471
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + + Y+ + V FG S P+ +
Sbjct: 472 PPPPVPWRIFGLDAMYV--VMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAY 529
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP + + L + +G + R P ++ SL +
Sbjct: 530 S-VNASDKGEASCCDPLG------AAFEGCLKRLFTQWGSFCVRNPGSIIFFSLVFIAAC 582
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H P
Sbjct: 583 SSGLVFVRVTTNPVDLWSAPNSQARLEKEYFDAHFGPFFRTEQLIIQAPHTDRHTYKPYP 642
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D ++E+L ++ Q ++ I A+Y+ V+L DICL PL ++C S+
Sbjct: 643 SGADVPFGPPLDLEILHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTIMSV 702
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 703 LNYFQNSHSMLDHKIGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 762
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 763 LVLGGYDDQNYGNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 810
>G3HT60_CRIGR (tr|G3HT60) Niemann-Pick C1 protein (Fragment) OS=Cricetulus
griseus GN=I79_014078 PE=4 SV=1
Length = 1137
Score = 204 bits (519), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 246/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DLL Q LCP GNV CC
Sbjct: 3 SQSCVWYGECGIAFGDKKYNCKYSGPP-KPLPKDGNDLL----QELCPGFFFGNVSLCCD 57
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QLQ + L CP+C N + LFCEL+CSP+QS F+NVT+ +
Sbjct: 58 VQQLQTLKSNLQLPMQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYVDPKTQE 117
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ Y+ ++F +Y+AC DV+ N +A+ + A A N W ++ K
Sbjct: 118 NKTNVKELEYYIGQSFANEMYNACPDVEAPASNEKALGILCGKDASACNATNWIEYMFNK 177
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
P + I IL PM D G
Sbjct: 178 NNGQAPFTITPIFSDLPILGMEPMRNATKGCKESVDEVTGPCSCQDCSIVCGPKPQPPPT 237
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ + ++ V + V Y+ +F+ FG + S P+ +
Sbjct: 238 PVPWRILGLDAMYV-----IMWVTYMAFLFIFFGGLLAVWCHRRRYFVSEYTPIDSNIAF 292
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S +N GE DP + + L + +G + R PT V+ SL +
Sbjct: 293 S-SNTSDKGEASCCDPLG------AAFDDCLRRMFTKWGAFCVRNPTCVIFFSLVFITAC 345
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P +LW P S+A EKE+FD H PF+R+EQLII SEH P
Sbjct: 346 SSGLVFVRVTTNPVELWSAPHSRARLEKEYFDKHFGPFFRMEQLIIQAPNTSEHIYEPYP 405
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D N E+L ++ Q ++ I +Y+ V+L DIC+ PL ++C S+
Sbjct: 406 SGSDVSFGPPLNKEILHQVLDLQIAIESITTSYNNKTVTLQDICVAPLSPYNKNCTIISV 465
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + TS + C F P+ P
Sbjct: 466 LNYFQNSHSVLDHQVGDDFYVYADYHTHFLYCVRAPTSLNDTSLLHDPCLGTFGGPVFPW 525
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PV+N ++ +A AWEK FI K
Sbjct: 526 LVLGGYDDQNYNNATALVITFPVSNYYNDT-EKLQRAQAWEKEFIDFVK 573
>L5K297_PTEAL (tr|L5K297) Niemann-Pick C1 protein OS=Pteropus alecto
GN=PAL_GLEAN10023157 PE=4 SV=1
Length = 1297
Score = 204 bits (519), Expect = 8e-50, Method: Compositional matrix adjust.
Identities = 172/602 (28%), Positives = 253/602 (42%), Gaps = 78/602 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI 83
A++ S S+ ++ C Y CG S K NC Y P KP +DL +Q LCP
Sbjct: 32 ASEFSDSLVFSQSCVWYGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGF 86
Query: 84 T-GNV--CCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
GN+ CC +QLQ + L CP+C N LN+FCEL+CSP QS F+NVT+
Sbjct: 87 FFGNISLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLLNMFCELTCSPRQSEFLNVTAT 146
Query: 133 SQV------DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NY 183
+ V + YV E+F +Y+AC+DV+ + N +A+ + G A N
Sbjct: 147 EDYFDPVIHETKTNVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKDAKDCNA 206
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXX 240
W ++ K +P++I + L + M+ MN + C+ D G
Sbjct: 207 TNWIEYMFNK---DNGQAPFTITPIFSDLPAHGMKPMNNATKGCDESVDEVTGPCSCQDC 263
Query: 241 XXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXX 300
+ + ++ V + Y+ + V FG
Sbjct: 264 SAVCGPEPKPPPPPVPWRILGLDAMYV-----IMWTTYMAFLLVFFGAFFAVWCYRKRYF 318
Query: 301 GSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPT 360
S P+ + S N GE DP + + L + +G + R P
Sbjct: 319 VSEYTPIDSNIAFS-VNARDKGEASCCDPLG------AAFEGCLRRLFTQWGSFCVRNPG 371
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
V+ SL + GL+ V T P LW P S+A EKE+FD+H PF+R EQLII
Sbjct: 372 CVIFFSLVFIATCSSGLVFVQVTTNPVHLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIR 431
Query: 421 TLPESEHGKPPSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKP 470
+ H P D +IE+L ++ Q ++ I +Y+ VSL DICL P
Sbjct: 432 APHTATHTYQPYPTETDVPFGPPLDIEILHQVLDLQTAIENISVSYNNETVSLQDICLAP 491
Query: 471 L---GEDCATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TE 511
L +C S+L YFQ D+ G + H YC + S +
Sbjct: 492 LSPYNNNCTIMSVLNYFQNSHSTLDHKIGDDFYVYADYHTHFLYCVRAPASLNDTSLLHD 551
Query: 512 TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
C F P+ P LGG+ NYS A+A +IT+ VNN ++ +A AWE+ FI
Sbjct: 552 PCLGTFGGPVFPWLVLGGYDDQNYSNATALVITFLVNNYYNNT-EKLQRAQAWEREFINF 610
Query: 572 AK 573
K
Sbjct: 611 VK 612
>M3Y344_MUSPF (tr|M3Y344) Uncharacterized protein OS=Mustela putorius furo
GN=Npc1 PE=4 SV=1
Length = 1276
Score = 203 bits (517), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 164/586 (27%), Positives = 246/586 (41%), Gaps = 72/586 (12%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTEEQ 93
C Y CG + K NC Y P KP +DL+ Q LCP +VCC +Q
Sbjct: 25 CVWYGECGIAAGDKRYNCQYSGPP-KPLPKDGYDLM----QELCPGFFFDNVSVCCDVQQ 79
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT----- 140
L+ + L CP+C N +NLFCEL+CSP QS F+NVT +T
Sbjct: 80 LRTLKDSLQLPLQFLSRCPSCFYNLMNLFCELTCSPQQSQFLNVTETEDYVDPVTNQTKT 139
Query: 141 -VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPP 196
V + YV E+F +Y+AC+DV+ + N +A+ + AGA N W ++ K
Sbjct: 140 NVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKDAGACNATNWIEYMFNK--- 196
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXX 256
+P++I + L + ME MN + C+++
Sbjct: 197 DNGQAPFTITPIFSDLPAHGMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPRPQPPPP 256
Query: 257 XXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
++ L + + + + Y+ + V FG + S P+ + S
Sbjct: 257 PAPWRI--LGLDAMYVIMWTTYMAFLLVFFGAVFAVWCYRKRYFVSEYTPIDSNIAFS-V 313
Query: 317 NLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
N GE D + + WL + +G + R P ++ SLA + G
Sbjct: 314 NASDKGEASCCDALG------AAFEGWLRRLFSHWGSFCVRNPGCIVVFSLAFIAACSSG 367
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
L+ V T P LW P S+A EKE+FD+H PF+R EQLII H P
Sbjct: 368 LVFVRVTTNPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIQAPHTPVHTYQPYPSGS 427
Query: 437 DN----------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSILQY 483
D + + ++Q ++ I A Y+ V+L DIC+ PL ++C S+L Y
Sbjct: 428 DVPFGPPLDRGILHQVLDLQTAIENITAFYNNETVTLQDICVAPLSPYNKNCTIMSVLNY 487
Query: 484 FQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTTAL 527
FQ D+ G + H YC + S + C F P+ P L
Sbjct: 488 FQNSHSVLDHEVGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVL 547
Query: 528 GGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
GG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 548 GGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>H3DBI8_TETNG (tr|H3DBI8) Uncharacterized protein (Fragment) OS=Tetraodon
nigroviridis GN=NPC1 PE=4 SV=1
Length = 1266
Score = 203 bits (516), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 172/601 (28%), Positives = 256/601 (42%), Gaps = 80/601 (13%)
Query: 27 LTAAQISRSIHSNEYCAMYDICGQRS--DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT 84
+T+A +S+ +C Y C + S GK NC Y P +Q LCP
Sbjct: 14 ITSAPVSQV--EAHHCVWYGECDESSLVPGKKYNCNYTGPPRPLPQEGYEVLQELCPGYD 71
Query: 85 -GN--VCCTEEQLQA------VPI--LVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS 133
GN +CC QL VP+ L CPAC N +NLFCEL+CSP+QS F+N T +S
Sbjct: 72 YGNRSLCCDVNQLHTLKESLEVPLQFLSRCPACFFNLVNLFCELTCSPHQSQFMNATKLS 131
Query: 134 QVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFL 190
D V + Y+ TF +Y+AC+DV+ + N +A+ + G A N W ++
Sbjct: 132 GPD----VVEVQYYIGLTFANAMYNACRDVQAPSSNVKALSLLCGKDAKDCNATNWIQYM 187
Query: 191 ----GQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXX 246
++ P FP +P D S MN +C D
Sbjct: 188 FNTDNEQAP--FPITPIFSDVPV-----SGYTPMNNDTAACTDGLEDGSGPCSCQDCTNA 240
Query: 247 XXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFV---LFGWIXXXXXXXXXXXGSS 303
K+ + V + + + +L+FV L W S
Sbjct: 241 CGPRPVPPPTPAPWKILGMDAMTVIMWFSYMAFLLIFVGSLLIAWCHRKETIM-----SE 295
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVL 363
P+L S+ R N D E + +L + + +G + P +VL
Sbjct: 296 YGPILDSKNRPSLNRDNPDH----DDASCCETLGERFESYLRSCFSCWGSFCVLHPCVVL 351
Query: 364 CSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT-- 421
SL +V+ GL+ + T P LW P S+A +E+E+FDSH PF+R QLII +
Sbjct: 352 LGSLILVVASSGGLIYMRITTDPVDLWSSPSSQARQEREYFDSHFGPFFRTAQLIITSPL 411
Query: 422 ----LPESEHGKP----PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL-- 471
L G P ++++ D + + ++Q ++ + A Y G V+L DICL PL
Sbjct: 412 NDTFLYSPVMGGPDIPFKAVLSKDILHQVLDLQLDIESLVATYEGQSVTLKDICLAPLSP 471
Query: 472 -GEDCATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCF 514
++C S+L YFQ D+ E H YC S + C
Sbjct: 472 YNDNCTILSVLNYFQNSHSTLDHVLKDEFLVYADFHSHFLYCVSAPASLNDTTPLHDPCL 531
Query: 515 SAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAL--TKVGDENGKAIAWEKAFIQLA 572
F P+ P ALGG+ NY+ A+A ++T+P+NN TK+ GK +AWEK FI+
Sbjct: 532 GTFGGPVFPWLALGGYDDTNYNNATALVVTFPINNNYDPTKL----GKTLAWEKEFIRFM 587
Query: 573 K 573
K
Sbjct: 588 K 588
>H2NW18_PONAB (tr|H2NW18) Uncharacterized protein OS=Pongo abelii GN=NPC1 PE=4
SV=1
Length = 1243
Score = 203 bits (516), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 172/589 (29%), Positives = 249/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME MN + C+++
Sbjct: 197 ---DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKP 251
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
L + + + + + Y+V + V FG S P+ +
Sbjct: 252 QPPPPPAPWTILGLDAMYVIMWITYMVFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL V
Sbjct: 312 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFVTAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+Y+ V+L DICL PL +C S+
Sbjct: 425 SGADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCTIMSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>F1SBB5_PIG (tr|F1SBB5) Niemann-Pick C1 protein OS=Sus scrofa GN=NPC1 PE=4 SV=2
Length = 1277
Score = 203 bits (516), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 167/589 (28%), Positives = 249/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCRYSGPP-KPLPEDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QL+ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VQQLRTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ YV ETF +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELEYYVGETFANAMYNACRDVEAPSSNEKALGLLCGREAQACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + C+++
Sbjct: 197 ---DNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQP 253
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + + Y+ + V FG S P+ +
Sbjct: 254 PPPPVPWRILGLDAMYVIMWSS--YMAFLIVFFGAFFAVWCYRKRYFVSEYTPIDGNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N G+ DP + + L + +G + R P V+ SLA ++
Sbjct: 312 S-VNSSDKGQAFCCDPLG------AAFERGLRRLFAQWGAFCVRHPGCVVFFSLAFIVAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP-- 431
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H P
Sbjct: 365 SSGLVFIRVTTDPVDLWSAPGSQARREKEYFDTHFGPFFRTEQLIIRATNNQSHIYHPYP 424
Query: 432 --------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
++ D + + ++Q ++ I A+Y+ V+L DICL PL ++C S+
Sbjct: 425 AGADVPFGPPLSRDILHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGG---------VEHAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHQVGDFFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWE FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWESEFINFVK 592
>F6XL99_HORSE (tr|F6XL99) Uncharacterized protein OS=Equus caballus GN=NPC1 PE=4
SV=1
Length = 1277
Score = 202 bits (515), Expect = 2e-49, Method: Compositional matrix adjust.
Identities = 172/592 (29%), Positives = 252/592 (42%), Gaps = 78/592 (13%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DLL Q LCP + GNV CC
Sbjct: 22 SQSCVWYGECGIAFGDKRYNCEYSGPP-KPLPKDGYDLL----QELCPGLFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTS----ISQVDGN 138
+QLQ + L CP+C N +NLFCEL+CSP QS F+NVT+ + V
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPQQSQFLNVTATEDYVDPVTNQ 136
Query: 139 MTVDGIDL--YVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
+ I+L YV E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVIELQYYVGESFANAMYNACRDVEAPSSNDKALGILCGKEAEACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXX 250
+P++I + + ME MN + CN D G
Sbjct: 197 ---NNGQAPFTITPIFSDFPAHGMEPMNNATKGCNESVDEVTGPCSCQDCSVVCGPKPQP 253
Query: 251 XXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
+ + ++ V + Y+ + + FG S P+ +
Sbjct: 254 PPAPAPWRILGLDAMYV-----IMWTTYMAFLLMFFGAFFAVWCYRKRYFVSEYTPIDSN 308
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
S N GE DP + + L + +G + R P V+ SLA +
Sbjct: 309 IAFS-VNASDKGEAACCDPLG------AAFEGCLRRLFARWGSFCVRNPGCVVVFSLAFI 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H
Sbjct: 362 AACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDAHFGPFFRTEQLIIRAPHGHVHTYE 421
Query: 431 PSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCAT 477
P D +E+L ++ Q ++ I A+Y+ V+L DICL PL ++C
Sbjct: 422 PYPSGADVPFGPPLALEVLHQVLDLQTAIENITASYNNETVTLQDICLAPLSPYNKNCTI 481
Query: 478 QSILQYFQ---------MDPDNFDNYGGVEHAEYCFQHYTST-------ETCFSAFKAPL 521
S+L YFQ ++ D F H YC + S + C F P+
Sbjct: 482 MSVLNYFQNSHSMLDHKVEDDFFVEADYHTHFLYCVRAPASLNDTTLLHDPCLGTFGGPV 541
Query: 522 EPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A+AWE+ FI K
Sbjct: 542 FPWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRALAWEREFINFVK 592
>G3V7K5_RAT (tr|G3V7K5) Protein Npc1 OS=Rattus norvegicus GN=Npc1 PE=4 SV=1
Length = 1278
Score = 202 bits (513), Expect = 4e-49, Method: Compositional matrix adjust.
Identities = 170/589 (28%), Positives = 252/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP + GNV CC
Sbjct: 23 SQSCVWYGECGVAFGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGLFFGNVSLCCD 77
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QLQ + L CP+C N + LFCEL+CSP+QS F+NVT+ +
Sbjct: 78 VQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPETRE 137
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V ++ YV +F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 138 NKTNVKELEYYVGRSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNK 197
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L ME M + CN++
Sbjct: 198 ---DNGQAPFTIIPVFSDLSVLGMEPMRNATKGCNESVDEVTGPCSCQDCSAVCGPKPQP 254
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++ L V + +A Y+ + + FG + S P+ +
Sbjct: 255 PPPPVPWRILGLDAMYVIMWVA--YMAFLVLFFGGLLAVWCHRRRYFVSEYTPIDSNIAF 312
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S +N GE DP + +F + L + +G + R PT ++ SL +
Sbjct: 313 S-SNSSDKGEASCCDP-----LGVAF-DDCLRRMFTKWGAFCVRNPTCIIFFSLVFIAAC 365
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P +LW P S+A EKE+FD H PF+R EQLII S H P
Sbjct: 366 SSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNSSVHIYEPYP 425
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D N E+L ++ Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 426 SGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSV 485
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTSTET-------CFSAFKAPLEPT 524
L YFQ DN G + H YC + S C F P+ P
Sbjct: 486 LNYFQNSHAVLDNQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPW 545
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 546 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAWAWEKEFINFVK 593
>A5DNY6_PICGU (tr|A5DNY6) Putative uncharacterized protein OS=Meyerozyma
guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 /
JCM 1539 / NBRC 10279 / NRRL Y-324) GN=PGUG_04987 PE=4
SV=2
Length = 1248
Score = 201 bits (511), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 154/552 (27%), Positives = 245/552 (44%), Gaps = 51/552 (9%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN--VCCTEEQ 93
H+ CAMYD CG++S G L CP P + KP ++S+C + VCCT +Q
Sbjct: 21 HTPGTCAMYDNCGKKSIFGAQLPCPGPLEAQKPSSEARELLESVCGAEFSSRLVCCTLDQ 80
Query: 94 LQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI--SQVDGNMTVDG 143
L+ + PI+ CPAC +NF + FC +CSP+QS F+NVT I +Q V
Sbjct: 81 LKNLESNLKKVDPIISSCPACRKNFYDFFCNFTCSPDQSTFVNVTRIGVAQDTKKEIVTE 140
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+ +V F E Y +CK+VKF N A+D +G GA NY ++ FLG + P GSP+
Sbjct: 141 LSQFVDPGFAEQFYDSCKEVKFSATNGYAMDLIGGGAKNYSQFLKFLGDE-KPLLGGSPF 199
Query: 204 SIDFKTTILD---SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
I+FK + D +S ++L + SCND
Sbjct: 200 QINFKYEVNDEEKASGLQLRTGDMKSCNDKEYRCACSDCSLSCPELPAFAGYDK------ 253
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
K + C ++ ++++ L L G+ S +L ++
Sbjct: 254 KCSVGPIPCFSFAVLMIWLALFLALAGY-HVYLVRTKEARWSQMNDILEDAVNAYD--AT 310
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWL----SNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
D + QN + S +QE L +F+ G + AR P + SL + + G
Sbjct: 311 DDTITTKSISLQNSI--SALQEELFIAIQSFFEDLGSFCARFPLFTIGVSLVVTVFFSLG 368
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
L E P LWV P A + +FF+ + ++R+EQ+II+T ++ P I+
Sbjct: 369 LSYLEFEQNPINLWVSPSEPALQNLQFFEQNFGEWFRVEQMIIST----KNSTP--ILNW 422
Query: 437 DNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYGG 496
+N+ FE ++++ + V L D+C KPLG+ CA +S QYF + D +
Sbjct: 423 ENVRWWFEKEQELQNLDG------VPLEDLCFKPLGDTCAIESFTQYFGGNIDYLNERNW 476
Query: 497 VEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGD 556
+ C S TC +F+ PL F ++ + AF++T V++ +K
Sbjct: 477 KSKLQGC---TDSPVTCLPSFQQPLNKNLL---FDRDDVLYSEAFVVTLLVSSN-SKDFK 529
Query: 557 ENGKAIAWEKAF 568
KA+ +E
Sbjct: 530 YTEKAVKYEHGL 541
>G1P8K0_MYOLU (tr|G1P8K0) Uncharacterized protein (Fragment) OS=Myotis lucifugus
PE=4 SV=1
Length = 1283
Score = 201 bits (511), Expect = 7e-49, Method: Compositional matrix adjust.
Identities = 164/582 (28%), Positives = 245/582 (42%), Gaps = 64/582 (10%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSP-SVKPHDLLSAKIQSLCPTIT-GNV--CCTEEQLQAV 97
C Y CG S K NC Y P P D +Q LCP + GNV CC +QL+ +
Sbjct: 32 CVWYGECGIASGDKRYNCEYSGPPKALPKDGYDL-VQELCPGLFFGNVSLCCDVQQLRTL 90
Query: 98 P--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------DGNMTVDG 143
L CP+C N +NLFCEL+CSP QS F+NVT + + V
Sbjct: 91 KDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTETEEYVDPVTHENKTNVKE 150
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPPGFPG 200
+ YV E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 151 LQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKEAAACNATNWIEYMFNK---DNGQ 207
Query: 201 SPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
+P++I + L + ME MN + C +
Sbjct: 208 APFTITPVFSDLPAHGMEPMNNATKGCAEPVDEVTGPCSCQDCSAVCGPRPQPPPPPVPW 267
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
++ L V + Y+ + + FG I S P+ S + +
Sbjct: 268 RIWGLDAMYV--VMWATYMAFLLMFFGAIFAVWCYRKRYLVSEYTPIDSSIAFPMS-VSD 324
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
GE DP + + L + +G + R P V+ SSLA + GL+
Sbjct: 325 TGEASCCDPLG------AAFEGCLRRLFTRWGSFCVRNPGCVIFSSLAFIAACSSGLVFV 378
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN-- 438
+ T P LW P S+A EKE+FD+H PF+R EQLII + H P D
Sbjct: 379 RITTSPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTAVHTYEPYPSGSDVPF 438
Query: 439 --------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSILQYFQ-- 485
+ + ++Q ++ I A+++ V+L DICL PL ++C S+L YFQ
Sbjct: 439 GPPLDKGILHQVLDLQTAIEHITASHNNETVTLQDICLAPLSPYNKNCTILSVLNYFQNS 498
Query: 486 ---MDP---DNFDNYGGVE-HAEYCFQHYTS-------TETCFSAFKAPLEPTTALGGFS 531
+D D+F Y H YC + S + C F P+ P LGG+
Sbjct: 499 HSVLDHEIGDDFYTYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYD 558
Query: 532 GNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
NY+ A+A ++T+PVNN ++ +A AWE+ FI K
Sbjct: 559 DQNYNNATALVMTFPVNNYYNDT-EKLQRAQAWEREFINFVK 599
>K1PF48_CRAGI (tr|K1PF48) Niemann-Pick C1 protein OS=Crassostrea gigas
GN=CGI_10006575 PE=4 SV=1
Length = 1285
Score = 201 bits (510), Expect = 8e-49, Method: Compositional matrix adjust.
Identities = 161/590 (27%), Positives = 261/590 (44%), Gaps = 78/590 (13%)
Query: 44 MYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKI-QSLCPTITGN----VCCTEEQLQA-- 96
MY C + G LNC Y P ++ +I ++ CP I + CC QL++
Sbjct: 1 MYGECQEGPTGN-LNCVYDGPPKPMNESEGLEILRTYCPNIVTSDQPLTCCDLAQLRSFK 59
Query: 97 ----VP--ILVGCPACLRNFLNLFCELSCSPNQSLFINVTS-----ISQVDGNMTVDGID 145
VP +L+ CP+C NFL LFC +C P Q+ F+ V+ + D V +D
Sbjct: 60 KNMGVPQQLLLRCPSCYYNFLYLFCYFTCDPMQADFLKVSMKMPNIANPSDPREVVYSVD 119
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPPGFPGSP 202
+V+ET+ G+Y++CKDV+ + N +A+D + A + ++W ++G +P
Sbjct: 120 YHVSETYAYGMYNSCKDVQMPSTNAKALDIICGKPAADCSAQDWLNYMGST---SNGQTP 176
Query: 203 YSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
++I++ + + MN SV C D G +
Sbjct: 177 FAINYHIDNTSTVDIHPMNHSVTPC-DQKYGNLSACSCQDCQATCAPLPPPPSPREPCTV 235
Query: 263 GSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDG 322
L + C ++ + +I V +I + P S KD
Sbjct: 236 --LGMDCWFFAMLITFIAFCVVFLSFIIVSMFF------NRNRPAKTENKWSQDKKYKDS 287
Query: 323 EVLVIDPQRQNEVQYS--FIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
L R +Q +I+ L +R +G + A+ P ++ + L + + G++ F
Sbjct: 288 SSLE-GKHRGTVLQRGGLWIETSLEMVFRRWGTFCAKNPVKIIVAGLVLGAVFSVGIVMF 346
Query: 381 NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG------------ 428
V T P KLW S+A +EK +FDSH PFYR +QLII T PE+ G
Sbjct: 347 EVTTSPVKLWSAENSRARQEKNYFDSHFGPFYRTQQLII-TRPENASGVRHEVPGINYGI 405
Query: 429 --KPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQSILQY 483
SI + + ++Q + + A++ G V+L DIC +PL DC QSIL+Y
Sbjct: 406 YRNYTSIFDKSFLHKVLDLQLTIQNLEADHKGSKVALEDICFQPLAPDNTDCTIQSILEY 465
Query: 484 FQ-----MDPDNFDNYGG-------VEHAEYCF--------QHYTSTETCFSAFKAPLEP 523
+Q +D +D+Y G ++H C QH+ +C A P+ P
Sbjct: 466 WQNNHTRLDKIKYDDYSGFYVEGDYLDHFSDCARAPASVSDQHHMDL-SCLGASGQPIFP 524
Query: 524 TTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+LGGF+G Y+E++A +IT+ VNN + + +N KA AWE F++ K
Sbjct: 525 WISLGGFTGEKYNESTALVITFVVNNHVDE--KQNEKARAWELEFLRFMK 572
>M4APW1_XIPMA (tr|M4APW1) Uncharacterized protein OS=Xiphophorus maculatus
GN=NPC1 PE=4 SV=1
Length = 1277
Score = 201 bits (510), Expect = 9e-49, Method: Compositional matrix adjust.
Identities = 161/592 (27%), Positives = 252/592 (42%), Gaps = 85/592 (14%)
Query: 40 EYCAMYDIC--GQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GN--VCCTEEQL 94
++C Y C ++ GK NC Y P V + + LCP GN +CC E QL
Sbjct: 35 QHCVWYGECDESEKVPGKKYNCNYTGPPVPLNPEGYELLTELCPGYNYGNRSLCCNETQL 94
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDL 146
+ L CP+C N +NLFCEL+CSP+QS F+N T + G V+ ++
Sbjct: 95 HTLKGSLQLPLQFLSRCPSCFYNLMNLFCELTCSPHQSQFMNAT---KFKGKNVVE-VEY 150
Query: 147 YVTETFGEGLYSACKDVKFGTMNTRAIDFVGA------GANNYKEWFAFLGQKVPPGFPG 200
Y+ +TF +Y+AC+DV+ + N +A+ + A N+ ++ + P FP
Sbjct: 151 YIGKTFANAMYNACQDVQAPSSNVKALSLLCGKDAQECNATNWIQYMFSIDNGQAP-FPI 209
Query: 201 SPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXXXXX 257
P D ++ S MN Y+C + G
Sbjct: 210 IPVFSD-----VEVSGYTPMNNKTYACTEGLEDGSGPCSCQDCAAACGPKPVPPPLPPPW 264
Query: 258 XXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTN 317
+ M ++ V + + Y+ + + G + S P+L S N
Sbjct: 265 TILGMDAMSV-----IMWIAYMAFLLIFAGVLVGAWCFRKRTITSEYGPILDS------N 313
Query: 318 LPKDGEVLVIDPQRQNEVQYS-------FIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
P L ++ N+ S + L F+ +G + R P++VL S +V
Sbjct: 314 NP-----LSLNSDNHNQENASCCETLGERFENLLRTFFSCWGSFCVRHPSVVLLGSFVLV 368
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
GL+ + T P +LW P S+A +EK +FD H PF+R QLII T +
Sbjct: 369 TACSGGLVYMRITTDPVELWSSPASQAHQEKSYFDEHFGPFFRTTQLIITTPINDTYIYS 428
Query: 431 P----------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCAT 477
P +I+ D + + ++Q +++ + A + G ++L DICL PL +C
Sbjct: 429 PYFGGSDVPFKAILFKDILHQVLDLQLEIENLVAEHDGKNITLKDICLAPLAPYNNNCTI 488
Query: 478 QSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPL 521
S+L YFQ D+ G E H YC S + C F P+
Sbjct: 489 LSVLNYFQNSHAVLDHSKGDEFFVYADYHSHFLYCVSAPASLNDTTVLHDPCLGTFGGPV 548
Query: 522 EPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P ALGG+ NY+ A+A +IT+P+NN L + G+A+AWEK FI+ K
Sbjct: 549 FPWLALGGYDETNYNNATALVITFPLNNYLND-SVKMGQALAWEKEFIKFMK 599
>E7RBT3_PICAD (tr|E7RBT3) Vacuolar membrane protein OS=Pichia angusta (strain
ATCC 26012 / NRRL Y-7560 / DL-1) GN=HPODL_4056 PE=4 SV=1
Length = 1268
Score = 199 bits (507), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 162/559 (28%), Positives = 248/559 (44%), Gaps = 54/559 (9%)
Query: 32 ISRSIHSNEYCAMYDICGQRS--DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNV-- 87
+++++HS CAMY G++S G N P P+ S P LLSA+ +SL +I G+
Sbjct: 10 VAQAVHSPGVCAMYGSGGKKSLFGG---NLPAPNNSAAP--LLSAQDRSLLVSICGDTWE 64
Query: 88 -----CCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI-S 133
CC +QL +A P++ CPAC NF LFC +CS NQS F+NVT +
Sbjct: 65 HEQYACCDGDQLNDLQTQLHKAEPLISSCPACKDNFFQLFCHFTCSANQSTFVNVTRTGT 124
Query: 134 QVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQK 193
+ G V+ D+ V Y +CK++KF N A+D +G GA NY ++ FLG +
Sbjct: 125 SLSGLPVVEEADVQVDAAMAAQFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFLGDE 184
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
P GSP+ I+F T + S + + + ++C+D
Sbjct: 185 -KPMLGGSPFQINFHTQ--NDSELVPLALAFHACDDED---ENFRCACADCPGSCPSLPE 238
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
++G L C S +VLV+ L G + ++ L + +
Sbjct: 239 LKRQESCRVGVLP--CFSFS-----VVLVYSL-GLALYIGLYAVAVARTRSQTLFLDQLE 290
Query: 314 SFTNLPKDGEVLV-IDPQRQNEVQYS-----FIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
S D E+L D Q N Y + L ++ G ++RP +V+ SL
Sbjct: 291 SPAFTGSDTELLEGSDDQFDNFDHYVAKDSYIVNNALEKWFAKLGLKCSQRPWLVIGLSL 350
Query: 368 AIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH 427
+LL +L +ET P LWV P S + E++ +D PFYR +Q+ +A +
Sbjct: 351 GASVLLSLFVLMIQLETNPVNLWVSPTSASYLERKVYDESFGPFYRTQQIFLA------N 404
Query: 428 GKPPSIVTD-DNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQM 486
S++ D IE F ++++ + A V+ D+C KPLGE CA +S QYF
Sbjct: 405 STGDSVLQDYRAIEWWFAKEQEILALTAQVDNTTVAYDDLCFKPLGETCALESFTQYFYG 464
Query: 487 DPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYP 546
D + C S C +F PL+P GGFS + S A A +IT
Sbjct: 465 DISQLPESSWQTKIQNC---ADSPVNCLPSFGQPLKPQLVFGGFSDSVLS-AKALVITLL 520
Query: 547 VNNALTKVGDENGKAIAWE 565
+NN + ++AWE
Sbjct: 521 LNNNNDPHDPQIKNSLAWE 539
>K5WIE2_PHACS (tr|K5WIE2) Uncharacterized protein OS=Phanerochaete carnosa
(strain HHB-10118-sp) GN=PHACADRAFT_249391 PE=4 SV=1
Length = 1391
Score = 199 bits (507), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 162/598 (27%), Positives = 258/598 (43%), Gaps = 92/598 (15%)
Query: 41 YCAMYDICGQRS-DGKVLNCPYPSPSVKP---HDLLSAKIQSLCPT--ITGNVCCTEEQL 94
YCAM CG + K L CP P+ + DLL S+C G CCT +QL
Sbjct: 7 YCAMRSHCGPKDWVSKSLPCPSNEPASEEGVDRDLLV----SICGEEFADGGTCCTTDQL 62
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGID 145
+A+ I+ CPAC NF +C +CSP+Q+ F+NVTS + V V +D
Sbjct: 63 EALRDNLGQAENIIASCPACRNNFRKFWCTFTCSPDQATFLNVTSTQKSVLDQTAVKSVD 122
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
V+E FG+G Y +CK ++ G N A+D +G GA +Y+ + F+G GSP+ I
Sbjct: 123 FIVSERFGQGFYDSCKSIQVGATNGYAMDLIGGGAKDYRSFLQFMGDVKD---IGSPFQI 179
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+F + M +A +C D LG +G+
Sbjct: 180 NFPEQV--PPEMTPFDARPRNCADNDLGSRCTCIDCPSVCQTLPPVPPPGSEPSCHVGAF 237
Query: 266 KVRCVDLSLAVLY--IVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLP---- 319
C+ SL +LY VL FV+ G+I S E + +S + N P
Sbjct: 238 S--CLSFSLVILYGLCVLAFVV-GYIIPFTIRKRKE--RSYERVALSADGASDNTPLSPR 292
Query: 320 ------------------------KDGEVL-----VIDPQRQNEVQYSFIQEWLSNFYRA 350
D L ++DP + + + +L +
Sbjct: 293 SHSRGLVGASSLAHQDVDESSGNFSDSRHLGRGASLLDPIETVQPRQYRLNAYLRRTFYR 352
Query: 351 YGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAP 410
G AA P + A + LL FG F +ET P +LWV P+S++ +KE+FD H P
Sbjct: 353 LGLLAATYPWMTFAVMFAFMALLNFGWSEFKIETDPVRLWVAPDSESRMQKEYFDEHFGP 412
Query: 411 FYRIEQLIIATLPES--------------EHGKPPSIVTDDNIELLFEIQEKVDEIRANY 456
FYR +Q+ + +S KPP +++ D+++ I+ ++ E++++
Sbjct: 413 FYRPQQIYVTVATQSPFDLQGSDALAAVASEQKPP-VLSWDHLKYWLSIEAEIRELKSSP 471
Query: 457 SGLLVSLSDICLKPLGED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCF 514
+ +L D+C KPLG D C QS+ +F D + ++ + +C + S C
Sbjct: 472 N--TYTLDDVCFKPLGPDGACVVQSVGGWFGNDLEAYEPDTWEDRLSHCAK---SPVDCR 526
Query: 515 SAFKAPLEPTTALGGFSGNN----YSEASAFIITYPVNNALTKVGDENGKAIAWEKAF 568
F+ PL P LGG N Y E+ + +IT V+++L + + +A+ WE+
Sbjct: 527 PDFQQPLAPQYVLGGIPEVNDTKMYLESQSLVITIVVSDSLDR--EIQDRALEWERTL 582
>Q5KGS9_CRYNJ (tr|Q5KGS9) Vacuolar membrane protein, putative OS=Cryptococcus
neoformans var. neoformans serotype D (strain JEC21 /
ATCC MYA-565) GN=CNE02470 PE=4 SV=1
Length = 1330
Score = 199 bits (507), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 159/560 (28%), Positives = 246/560 (43%), Gaps = 69/560 (12%)
Query: 33 SRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCP---TITGNVC 88
S+S CAM CG+ S G L CP S + P L + S+C ++ +VC
Sbjct: 4 SQSRSGKGICAMRGTCGKTSMFGADLPCPDDSDATVPDQRLLDLMASVCGPSYSLPDHVC 63
Query: 89 CTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNM 139
CT +QL QA P++ CPAC+ NF + +C+ +CSPNQS F++VT+ + +G
Sbjct: 64 CTYDQLSTLSDRLQQAAPLIASCPACINNFRSFYCDFTCSPNQSTFLSVTATQKTTEGKD 123
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFP 199
V +D V+ F +G Y +CKDV+FG N A+D +G GA N + ++G + PG
Sbjct: 124 AVKEVDYEVSSDFKQGFYDSCKDVQFGATNGFAMDLIGGGATNASGFLKYMGD-LRPGL- 181
Query: 200 GSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
GSP+ I+F D+ A + SC+D
Sbjct: 182 GSPFQINFP----DNDDSAYRRAPL-SCSDAENINARCACADCPSVCPSLPYIAPPSTKQ 236
Query: 260 IKMGSLKVRCVDLSLAVLYIVLVFV---LFGWIXXXXXXXXX-----------------X 299
+G+ V C+ SL ++Y V++ V L+ W
Sbjct: 237 CHVGA--VSCLTFSLLIIYSVIILVGALLYIWKQAARHRQRRYERVALLDPPHSPTIQNG 294
Query: 300 XGSSAEPLLVS--------EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAY 351
GS + L+ G L + +L DP + + + I L F+
Sbjct: 295 QGSGLDGLMGRNDDAESGPSGSIHFRLGRGASLL--DPMEHLQPKQNKINATLRRFFYRL 352
Query: 352 GRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPF 411
G A+RP V S IV L FG F VET P +LWV P S++A +K+FFD PF
Sbjct: 353 GLTCAKRPIEVFAISALIVGLFNFGWKYFEVETDPVRLWVSPTSESASQKQFFDDSFGPF 412
Query: 412 YRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL 471
Y+ EQ+ I G P V D ++ +++ +++ ++ + + L DIC P
Sbjct: 413 YKSEQIFIT----QSSGSP---VNYDTLDWWLKVETEINALKTSDG---IGLEDICFAPA 462
Query: 472 GED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGG 529
G+ C QS+ + D + + G E + C F P++P LGG
Sbjct: 463 GKGTPCVIQSVSAWLGDDMEVW----GEEWESRVRDCASRPGECLPPFGQPIDPKLVLGG 518
Query: 530 FSGNNYSEASAFIITYPVNN 549
+G ++ EA A ++T+ VNN
Sbjct: 519 ANG-DWLEAKALVVTWVVNN 537
>L8XAN1_9HOMO (tr|L8XAN1) Patched sphingolipid transporter (Ncr1), putative
OS=Rhizoctonia solani AG-1 IA GN=AG1IA_00242 PE=4 SV=1
Length = 1246
Score = 199 bits (507), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 159/568 (27%), Positives = 245/568 (43%), Gaps = 67/568 (11%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLC-PTIT-GNVCCTEEQLQAVP- 98
C+M CG GK L CPY P + + S+C P G VCCT +Q+ +
Sbjct: 7 CSMRGKCGSNY-GKPLPCPYDGPPQELDQEGKDLLASVCGPKFAQGPVCCTTDQIATLKS 65
Query: 99 -------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDGIDLYVTET 151
++ CPAC NF +C +CSPNQ+ F+ VTS + V +D VTE+
Sbjct: 66 NFQTPDQLVSSCPACKNNFHEFYCHFTCSPNQADFVTVTSTEE----GAVKSVDFRVTES 121
Query: 152 FGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTI 211
+G G Y +CKDVKFG +N A+ +G GA NY ++F ++G P G SP+ I+F
Sbjct: 122 YGTGFYDSCKDVKFGGLNDNAMTLIGGGATNYHDFFKYMGAVRPIG---SPFQINFPQKA 178
Query: 212 LDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVD 271
+SS +NA V C TS G +G+
Sbjct: 179 -NSSWNSPLNAPVRDC--TSEGLDSRCTCLDCPGVCPTLPAIPGQGPTCTVGAWSCFTFG 235
Query: 272 L----SLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS----------------- 310
L +L VL ++ +++ +I SAE V+
Sbjct: 236 LVLVYALGVLAFLIGYLIQSFIRRRRRLRDERHALSAEAASVTGALVGAGSLQQRDGTES 295
Query: 311 ---EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
S NL + +L DP + + + L G A P
Sbjct: 296 TGTRSESRQNLGRGASLL--DPLDSLQPRQHKLNTHLRRGCYKLGLACATHPWATFTIVF 353
Query: 368 AIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH 427
A++ +L G +F VET P +LWV P S+ ++KE+FD H PFY+ EQL I + H
Sbjct: 354 ALIGILNLGWTKFEVETDPVRLWVAPNSELKQQKEYFDEHFGPFYKTEQLFITDI----H 409
Query: 428 GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED--CATQSILQYFQ 485
G P ++T ++ +I+ ++ +++ +G S D+C KP G C QS+ YF
Sbjct: 410 GGP--VMTYPRLKWWLDIENEIRALKSEPNGY--SHPDVCFKPAGPRGACVVQSVSAYFG 465
Query: 486 MDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNN-----YSEASA 540
D +++D VE E C + C F PL P LG ++ + +A A
Sbjct: 466 GDMEDWDEDSWVEQLEDC---ASQPAMCLPDFGQPLAPKYVLGSAPKDDEDNRIWHKAEA 522
Query: 541 FIITYPVNNALTKVGDENGKAIAWEKAF 568
++T+ V+++L + E +A WE+
Sbjct: 523 MVVTFVVSDSLDEAVRE--RAEEWERTL 548
>Q4RWY5_TETNG (tr|Q4RWY5) Chromosome 15 SCAF14981, whole genome shotgun sequence.
(Fragment) OS=Tetraodon nigroviridis
GN=GSTENG00027641001 PE=4 SV=1
Length = 1209
Score = 199 bits (506), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 159/549 (28%), Positives = 240/549 (43%), Gaps = 68/549 (12%)
Query: 76 IQSLCPTIT-GN--VCCTEEQLQA------VPI--LVGCPACLRNFLNLFCELSCSPNQS 124
+Q LCP GN +CC QL VP+ L CPAC N +NLFCEL+CSP+QS
Sbjct: 3 LQELCPGYDYGNRSLCCDVNQLHTLKESLEVPLQFLSRCPACFFNLVNLFCELTCSPHQS 62
Query: 125 LFINVTSISQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN-- 181
F+N T +S D V + Y+ TF +Y+AC+DV+ + N +A+ + G A
Sbjct: 63 QFMNATKLSGPD----VVEVQYYIGLTFANAMYNACRDVQAPSSNVKALSLLCGKDAKDC 118
Query: 182 NYKEWFAFL----GQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXX 237
N W ++ ++ P FP +P D S MN +C D
Sbjct: 119 NATNWIQYMFNTDNEQAP--FPITPIFSDVPV-----SGYTPMNNDTAACTDGLEDGSGP 171
Query: 238 XXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXX 297
K+ + V + + + +L+FV G +
Sbjct: 172 CSCQDCTNACGPRPVPPPTPAPWKILGMDAMTVIMWFSYMAFLLIFV--GSLLIAWCHRK 229
Query: 298 XXXGSSAEPLLVSEGRSFTNL--PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWA 355
S P+L S+ R N P ++D E + +L + + +G +
Sbjct: 230 ETIMSEYGPILDSKNRPSLNRDNPDHVPFFILDDASCCETLGERFESYLRSCFSCWGSFC 289
Query: 356 ARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIE 415
P +VL SL +V+ GL+ + T P LW P S+A +E+E+FDSH PF+R
Sbjct: 290 VLHPCVVLLGSLILVVASSGGLIYMRITTDPVDLWSSPSSQARQEREYFDSHFGPFFRTA 349
Query: 416 QLIIAT------LPESEHGKP----PSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSD 465
QLII + L G P ++++ D + + ++Q ++ + A Y G V+L D
Sbjct: 350 QLIITSPLNDTFLYSPVMGGPDIPFKAVLSKDILHQVLDLQLDIESLVATYEGQSVTLKD 409
Query: 466 ICLKPL---GEDCATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST--- 510
ICL PL ++C S+L YFQ D+ E H YC S
Sbjct: 410 ICLAPLSPYNDNCTILSVLNYFQNSHSTLDHVLKDEFLVYADFHSHFLYCVSAPASLNDT 469
Query: 511 ----ETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNAL--TKVGDENGKAIAW 564
+ C F P+ P ALGG+ NY+ A+A ++T+P+NN TK+ GK +AW
Sbjct: 470 TPLHDPCLGTFGGPVFPWLALGGYDDTNYNNATALVVTFPINNNYDPTKL----GKTLAW 525
Query: 565 EKAFIQLAK 573
EK FI+ K
Sbjct: 526 EKEFIRFMK 534
>I2CU31_MACMU (tr|I2CU31) Niemann-Pick C1 protein OS=Macaca mulatta GN=NPC1 PE=2
SV=1
Length = 1277
Score = 199 bits (506), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 169/588 (28%), Positives = 250/588 (42%), Gaps = 70/588 (11%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPY---PSPSVKP-HDLLSAKIQSLCPTIT-GNV--CCTE 91
++ C Y CG K NC Y P P K +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYFGPPKPLPKDGYDL----VQELCPGFFFGNVSLCCDV 77
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT--- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 78 QQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQT 137
Query: 141 ---VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKV 194
V + +V ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 138 KTNVKELQYFVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK- 196
Query: 195 PPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
+P++I + ME MN + C+++
Sbjct: 197 --DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKPQ 252
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
L + + + + + Y+ + V FG S P+ + S
Sbjct: 253 PPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFS 312
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
N GE DP V +F + L + +G + R P V+ SL + +
Sbjct: 313 -VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFIAVCS 365
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIV 434
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 366 SGLVFVRVTTNPIDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYPS 425
Query: 435 TDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSIL 481
D +I++L ++ Q ++ I A+Y+ V+L DICL PL +C S+L
Sbjct: 426 GADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCTIMSVL 485
Query: 482 QYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTT 525
YFQ D+ G + H YC + S + C F P+ P
Sbjct: 486 NYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWL 545
Query: 526 ALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI L +
Sbjct: 546 VLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINLVR 592
>H9FUY5_MACMU (tr|H9FUY5) Niemann-Pick C1 protein OS=Macaca mulatta GN=NPC1 PE=2
SV=1
Length = 1277
Score = 199 bits (506), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 169/588 (28%), Positives = 250/588 (42%), Gaps = 70/588 (11%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPY---PSPSVKP-HDLLSAKIQSLCPTIT-GNV--CCTE 91
++ C Y CG K NC Y P P K +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYFGPPKPLPKDGYDL----VQELCPGFFFGNVSLCCDV 77
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT--- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 78 QQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQT 137
Query: 141 ---VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKV 194
V + +V ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 138 KTNVKELQYFVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK- 196
Query: 195 PPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
+P++I + ME MN + C+++
Sbjct: 197 --DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKPQ 252
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
L + + + + + Y+ + V FG S P+ + S
Sbjct: 253 PPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFS 312
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
N GE DP V +F + L + +G + R P V+ SL + +
Sbjct: 313 -VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFIAVCS 365
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIV 434
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 366 SGLVFVRVTTNPIDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYPS 425
Query: 435 TDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSIL 481
D +I++L ++ Q ++ I A+Y+ V+L DICL PL +C S+L
Sbjct: 426 GADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCTIMSVL 485
Query: 482 QYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTT 525
YFQ D+ G + H YC + S + C F P+ P
Sbjct: 486 NYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWL 545
Query: 526 ALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI L +
Sbjct: 546 VLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINLVR 592
>Q55SD4_CRYNB (tr|Q55SD4) Putative uncharacterized protein OS=Cryptococcus
neoformans var. neoformans serotype D (strain B-3501A)
GN=CNBE2480 PE=4 SV=1
Length = 1330
Score = 199 bits (505), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 159/560 (28%), Positives = 245/560 (43%), Gaps = 69/560 (12%)
Query: 33 SRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCP---TITGNVC 88
S+S CAM CG+ S G L CP S + P L + S+C ++ +VC
Sbjct: 4 SQSRSGKGICAMRGTCGKTSMFGADLPCPDDSDATVPDQSLLDLMDSVCGPSYSLPDHVC 63
Query: 89 CTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNM 139
CT +QL QA P++ CPAC+ NF + +C+ +CSPNQS F++VT+ + +G
Sbjct: 64 CTYDQLSTLSDRLQQAAPLIASCPACINNFRSFYCDFTCSPNQSTFLSVTATQKTTEGKD 123
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFP 199
V +D V+ F +G Y +CKDV+FG N A+D +G GA N + ++G + PG
Sbjct: 124 AVKEVDYEVSSDFKQGFYDSCKDVQFGATNGFAMDLIGGGATNASGFLKYMGD-LRPGL- 181
Query: 200 GSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
GSP+ I+F D+ A + SC+D
Sbjct: 182 GSPFQINFP----DNDDSAYRRAPL-SCSDAENINARCACADCPSVCPSLPYIAPPSTKQ 236
Query: 260 IKMGSLKVRCVDLSLAVLYIVLVFV---LFGWIXXXXXXXXX-----------------X 299
+G+ V C+ SL ++Y V++ V L+ W
Sbjct: 237 CHVGA--VSCLTFSLLIIYSVIILVGALLYIWKQAARHRQRRYERVALLDPPHSPTIQNG 294
Query: 300 XGSSAEPLLVS--------EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAY 351
GS + L+ G L + +L DP + + + I L F+
Sbjct: 295 QGSGLDGLMGRNDDAESGPSGSIHFRLGRGASLL--DPMEHLQPKQNKINATLRRFFYRL 352
Query: 352 GRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPF 411
G A+RP V S IV L FG F VET P +LWV P S++A +K+FFD PF
Sbjct: 353 GLTCAKRPIEVFAISALIVGLFNFGWKYFEVETDPVRLWVSPTSESASQKQFFDDSFGPF 412
Query: 412 YRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL 471
Y+ EQ+ I G P V D ++ +++ +++ ++ + + L DIC P
Sbjct: 413 YKSEQIFIT----QSSGSP---VNYDTLDWWLKVETEINALKTSDG---IGLEDICFAPA 462
Query: 472 GED--CATQSILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGG 529
G+ C QS+ + D + + G E C F P++P LGG
Sbjct: 463 GKGTPCVIQSVSAWLGDDMEVW----GEEWESRVRDCAARPGECLPPFGQPIDPKLVLGG 518
Query: 530 FSGNNYSEASAFIITYPVNN 549
+G ++ EA A ++T+ VNN
Sbjct: 519 ANG-DWLEAKALVVTWVVNN 537
>G3TMS9_LOXAF (tr|G3TMS9) Uncharacterized protein OS=Loxodonta africana GN=NPC1
PE=4 SV=1
Length = 1277
Score = 199 bits (505), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 167/592 (28%), Positives = 249/592 (42%), Gaps = 78/592 (13%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG + K NC Y P KP +DL +Q LCP ++CC
Sbjct: 22 SQSCVWYGECGIAAGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------D 136
+QL+ + L CP+C N +NLFCEL+CSP QS F+NVT+ + +
Sbjct: 77 VQQLRTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPQQSQFLNVTATNDYVDPVTNE 136
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V+ + Y+ ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVEELQYYIGDSFANAMYNACRDVEAPSSNDKALGLLCGKDAKACNATNWIEYMFSK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXX 250
+P++I + L ME MN + C+ D G
Sbjct: 197 ---DNGQTPFTITPVFSDLPVLGMEPMNNATKGCDEAVDEVTGPCSCQDCSVVCGPKPQP 253
Query: 251 XXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
+ ++ V + + Y+ V V FG S P+ +
Sbjct: 254 PPPPAPWIIFGLDAMYV-----IMWITYMAFVLVFFGSFFAVWCYRKRYFVSEYTPIDSN 308
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
S N GE DP + + L + +G + R P V+ SL +
Sbjct: 309 MAFS-VNASDKGEASCCDPLG------AAFEGCLRRLFTRWGVFCVRNPGCVVFFSLVFI 361
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKP 430
+ GL+ V T P LW P S+ EKE+FD H PF+R EQLII + S+H
Sbjct: 362 GVCSSGLVFVRVTTNPIDLWSAPNSQGRREKEYFDMHFGPFFRTEQLIIRSPHTSKHIYQ 421
Query: 431 PSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCAT 477
P D NIE+L ++ Q ++ I A + V L DICL PL ++C
Sbjct: 422 PYPSGTDVPFGPPLNIEILHQVLDLQTAIENITALCNNQTVMLRDICLAPLSPYNKNCTI 481
Query: 478 QSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPL 521
S+L YFQ D+ G E H YC + TS + C F P+
Sbjct: 482 LSVLNYFQNSHSVLDHKVGDEFYTYADYHTHFLYCVRAPTSLNDTSLLHDPCLGTFGGPV 541
Query: 522 EPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A AWE+ FI K
Sbjct: 542 FPWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEREFINFVK 592
>H2U260_TAKRU (tr|H2U260) Uncharacterized protein (Fragment) OS=Takifugu rubripes
GN=LOC101069555 PE=4 SV=1
Length = 1264
Score = 199 bits (505), Expect = 3e-48, Method: Compositional matrix adjust.
Identities = 166/594 (27%), Positives = 254/594 (42%), Gaps = 90/594 (15%)
Query: 40 EYCAMYDICGQ--RSDGKVLNCPYPSPSVKPHDLLSAK---IQSLCPTI---TGNVCCTE 91
++C Y CG+ + GK NC Y P P LL + LCP ++CC
Sbjct: 24 QHCVWYGECGESEKVPGKKYNCNYTGP---PKPLLPEGYELLTELCPGYDYENRSLCCDV 80
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMTVDG 143
QL + L CPAC N +NLFCEL+CSP+QS F+N T S + V
Sbjct: 81 NQLHTLKGSLQLPLQFLSRCPACFFNLMNLFCELTCSPHQSQFMNGTKFSGPN----VVE 136
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFL-----GQKVP 195
+ Y+ +TF +Y+AC+DV+ + N +A+ + G A N W ++ GQ
Sbjct: 137 VQYYIGQTFANAMYNACRDVQAPSSNVKALSLLCGKDAKDCNATNWIQYMFDTNNGQ--- 193
Query: 196 PGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
+P+ I + + S MN Y+C +
Sbjct: 194 -----APFPITAIFSDVPVSGYTPMNNKTYACTEGLEDGSGPCSCQDCTDACGPTPVPPP 248
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
K+ L + + + + + Y+ +F+ G + S EP+L S
Sbjct: 249 PPLPWKI--LGIDAMTIIMWLSYMAFLFIFAGSLLVAWCHRKQTIKSEYEPILDS----- 301
Query: 316 TNLPKDGEVLVIDPQRQNEVQYS---FIQEWLSNFYR----AYGRWAARRPTIVLCSSLA 368
N P L ++ Q +V S + E NF R +G + P IVL S+
Sbjct: 302 -NNP-----LSLNRDNQEQVDASCCETLGERFENFLRTCFSVWGSFCVLHPFIVLLGSIV 355
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG 428
+V GL+ + T P LW P+S+A +EK++FDSH PF+R QLII +
Sbjct: 356 LVAASSGGLVYMQITTDPVDLWSSPKSQARQEKDYFDSHFGPFFRTAQLIITSPLNDTFI 415
Query: 429 KPP----------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDC 475
P +I++ D ++ + ++Q ++ + A Y G V+L DICL PL ++C
Sbjct: 416 YTPYFGGSDVPFKAILSKDILDQVLDLQLDIENLVATYEGQNVTLKDICLAPLSPYNDNC 475
Query: 476 ATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKA 519
S+L YFQ ++ G E H YC S + C F
Sbjct: 476 TILSVLNYFQNSHSVLNHSRGDEFYVYADYHSHFLYCVSAPASLNDTTLLHDPCLGTFGG 535
Query: 520 PLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P+ P ALGG+ NY+ A+A ++T+P+NN GK +AWEK FI+ K
Sbjct: 536 PVFPWLALGGYDDTNYNNATALVVTFPLNNNYDPA--RLGKTLAWEKEFIRFMK 587
>Q59GR1_HUMAN (tr|Q59GR1) Niemann-Pick disease, type C1 variant (Fragment)
OS=Homo sapiens PE=4 SV=1
Length = 1289
Score = 199 bits (505), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 170/589 (28%), Positives = 246/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 33 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 87
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 88 VRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 147
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 148 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 207
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME MN + C+++
Sbjct: 208 ---DNGQAPFTITPVFSDFPVRGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKP 262
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
L + + + + + Y+ + V FG S P+ +
Sbjct: 263 QPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 322
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 323 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 375
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 376 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYP 435
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+Y V+L DICL PL +C S+
Sbjct: 436 SGADVPFGPPLDIQILHQVLDLQIAIENITASYDNETVTLQDICLAPLSPYNTNCTILSV 495
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 496 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 555
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 556 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 603
>D2GUU3_AILME (tr|D2GUU3) Putative uncharacterized protein (Fragment)
OS=Ailuropoda melanoleuca GN=PANDA_000443 PE=4 SV=1
Length = 1231
Score = 198 bits (504), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 169/591 (28%), Positives = 248/591 (41%), Gaps = 78/591 (13%)
Query: 40 EYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTE 91
+ C Y CG S K NC Y P KP +DL+ Q LCP +VCC
Sbjct: 4 QACVWYGECGIASGDKRYNCQYSGPP-KPLPKDGYDLM----QELCPGFFFDNVSVCCDV 58
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVD-----G 137
+QL+ + L CP+C N +NLFCEL+CSP QS F+NVT S +D
Sbjct: 59 QQLRTLKDSLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTESEDYIDPVTNQT 118
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKV 194
V + YV E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 119 KTNVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFNK- 177
Query: 195 PPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXX 251
+P++I + L + ME MN + C+ D G
Sbjct: 178 --DNGQAPFTITPIFSDLPAHAMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQPP 235
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSE 311
+ + ++ V + Y+ + V FG S P+ +
Sbjct: 236 PPPAPWRILGLDAMYV-----IMWTTYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNI 290
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
S N GE D + + +L + +G + R P ++ SLA +
Sbjct: 291 AFS-VNASDKGEASCCDALA------AAFEGYLRRLFSRWGSFCVRNPGCIIFFSLAFIA 343
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 344 ACSSGLVFVRVTTNPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIQAPNTSAHTYQP 403
Query: 432 SIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQ 478
D +I +L ++ Q ++ I A Y+ V+L DIC+ PL ++C
Sbjct: 404 YPSGSDVPFGPPLDIGILHQVLDLQTAIENITAFYNNETVTLQDICVAPLSPYNKNCTIL 463
Query: 479 SILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLE 522
S+L YFQ D+ G + H YC + S + C F P+
Sbjct: 464 SVLNYFQNSHSLLDHKIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVF 523
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 524 PWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 573
>Q6FKT2_CANGA (tr|Q6FKT2) Similar to uniprot|Q12200 Saccharomyces cerevisiae
YPL006w OS=Candida glabrata (strain ATCC 2001 / CBS 138
/ JCM 3761 / NBRC 0622 / NRRL Y-65) GN=CAGL0L08888g PE=4
SV=1
Length = 1193
Score = 198 bits (504), Expect = 4e-48, Method: Compositional matrix adjust.
Identities = 154/546 (28%), Positives = 233/546 (42%), Gaps = 64/546 (11%)
Query: 42 CAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN-------VCCTEEQ 93
C +Y CG++S G L CP P ++ + + L + G +CCT +Q
Sbjct: 36 CTIYGNCGKKSIFGSQLPCPVDDLDFSP-PMIDEETRELLVSTCGKEWEDKDFICCTVDQ 94
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV-DGNMTVDGI 144
+ A+ I+ CPACL NF LFC +CSP Q F+ VT + DG VD +
Sbjct: 95 ITALKTNLQKAQTIISSCPACLENFNRLFCHFTCSPEQREFVKVTQKGKSSDGRSVVDEL 154
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
++Y+ +T+ + +CK+VKF N A+D +G GA NY ++ FLG K P GSP+
Sbjct: 155 EVYMNKTWASSFFDSCKEVKFSATNGYAMDLIGGGAKNYTQFLKFLGDK-KPALGGSPFQ 213
Query: 205 IDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGS 264
I+F + D N +VY+CNDT K
Sbjct: 214 INFVYELGDMDNYRYFNETVYACNDTVYKCACSDCELSCPTLEPLQNR--------KCSV 265
Query: 265 LKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEV 324
V C ++ +LY L+ W + L SE + N+ D +
Sbjct: 266 GPVPCFSFTVIILYFALLSAFIMWYALMKNTNKLSSAFLSSDNLFSEFENNENM--DNGM 323
Query: 325 LVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF---N 381
L E Q F+ +W+++ + W +P + L L ++L GLL F +
Sbjct: 324 LF----NNYETQTYFVNDWIADCSARWTSWIVSKPCVTLL--LVGTLILSMGLLLFCWGD 377
Query: 382 VETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIEL 441
+ET+P LWV S +EK++FD H PFYRI+Q+ I + P D+
Sbjct: 378 LETKPVNLWVSKNSPKFKEKQYFDDHFGPFYRIQQIFIV------NDTGPVFTDYDSFTW 431
Query: 442 LFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQMDPDNF-DNYGGVEH 499
FEI++ + E + GL S D C +P + C QS QYF PD +
Sbjct: 432 WFEIEKNITEHLVSTEGL--SYQDYCFRPTPDSACVIQSYAQYF---PDYLPEKEVWRNK 486
Query: 500 AEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENG 559
E C ++ + C F+ PL+ FS + +AF+ TY ++N
Sbjct: 487 LEECAKYPVN---CLPTFQQPLKSNLL---FSDEDPLGTNAFVATYLLSN-------HTE 533
Query: 560 KAIAWE 565
AI WE
Sbjct: 534 GAIQWE 539
>G1M5K1_AILME (tr|G1M5K1) Uncharacterized protein (Fragment) OS=Ailuropoda
melanoleuca GN=NPC1 PE=4 SV=1
Length = 1284
Score = 198 bits (504), Expect = 5e-48, Method: Compositional matrix adjust.
Identities = 169/591 (28%), Positives = 248/591 (41%), Gaps = 78/591 (13%)
Query: 40 EYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTE 91
+ C Y CG S K NC Y P KP +DL+ Q LCP +VCC
Sbjct: 31 QACVWYGECGIASGDKRYNCQYSGPP-KPLPKDGYDLM----QELCPGFFFDNVSVCCDV 85
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVD-----G 137
+QL+ + L CP+C N +NLFCEL+CSP QS F+NVT S +D
Sbjct: 86 QQLRTLKDSLQLPLQFLSRCPSCFYNLMNLFCELTCSPRQSQFLNVTESEDYIDPVTNQT 145
Query: 138 NMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKV 194
V + YV E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 146 KTNVKELQYYVGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFNK- 204
Query: 195 PPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXX 251
+P++I + L + ME MN + C+ D G
Sbjct: 205 --DNGQAPFTITPIFSDLPAHAMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQPP 262
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSE 311
+ + ++ V + Y+ + V FG S P+ +
Sbjct: 263 PPPAPWRILGLDAMYV-----IMWTTYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNI 317
Query: 312 GRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
S N GE D + + +L + +G + R P ++ SLA +
Sbjct: 318 AFS-VNASDKGEASCCDALA------AAFEGYLRRLFSRWGSFCVRNPGCIIFFSLAFIA 370
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 371 ACSSGLVFVRVTTNPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIQAPNTSAHTYQP 430
Query: 432 SIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQ 478
D +I +L ++ Q ++ I A Y+ V+L DIC+ PL ++C
Sbjct: 431 YPSGSDVPFGPPLDIGILHQVLDLQTAIENITAFYNNETVTLQDICVAPLSPYNKNCTIL 490
Query: 479 SILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLE 522
S+L YFQ D+ G + H YC + S + C F P+
Sbjct: 491 SVLNYFQNSHSLLDHKIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVF 550
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 551 PWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 600
>H3I2S2_STRPU (tr|H3I2S2) Uncharacterized protein OS=Strongylocentrotus
purpuratus PE=4 SV=1
Length = 1332
Score = 197 bits (502), Expect = 8e-48, Method: Compositional matrix adjust.
Identities = 167/637 (26%), Positives = 273/637 (42%), Gaps = 92/637 (14%)
Query: 15 LQVLILSWFSPSLTA-AQISRSIHSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLL 72
+ + + S F +T+ Q++ IH YC YD CG + K LNC Y KP +L
Sbjct: 10 VAITVFSIFCLGITSNVQVAAYIHKEGYCMWYDQCGTDAVTHKSLNCLYN----KPAKVL 65
Query: 73 SAK----IQSLCPTITG------NVCCTEEQLQA------VP--ILVGCPACLRNFLNLF 114
K +++LCP + CC+ QL +P + CP+C +N +N++
Sbjct: 66 DTKGLDTLKTLCPEMVAANESETKTCCSASQLDTFNYNMNIPRETMSRCPSCYKNLVNIY 125
Query: 115 CELSCSPNQSLFINV---------------TSISQVDGNMTVDGIDLYVTETFGEGLYSA 159
C L+CSP+QS+++N T + G ++ +D ++ + ++++
Sbjct: 126 CFLTCSPDQSMYVNASKTTPYSPPTPPPENTVQDKEAGQKSITEVDYFILNETAQAMFNS 185
Query: 160 CKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSS 215
C +V F + NT+ + GA + W F+G K +P+ I+FK +
Sbjct: 186 CINVNFPSSNTKVLSLYCGSYGAAHCTAQRWLDFMGDK---NNEQTPFQINFKLGGA-PA 241
Query: 216 PMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLA 275
PME M+ VY+CN+ + + V S A
Sbjct: 242 PMEPMDTRVYACNEAPNNNTQPCSCQDCPSSCPPLPPLPPPPPQFLVFGIDGYIVIFSAA 301
Query: 276 VLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL--VSEGRSFTNLPKDGEVLVIDPQRQN 333
+ ++VF+L +I G + S + N E+ + +
Sbjct: 302 YVVFLIVFILLNFICMCCNMCCKKGGENTGDCCDETSTAVNSVNGANRKEISEDEVGCKA 361
Query: 334 EVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGP 393
+F Q+ L +R G A P IVL + +V + G++R V T P +LW P
Sbjct: 362 SCGMAF-QKLLELCFRKLGTLVAGHPHIVLVLGVMVVTAMTAGMVRLKVTTDPVELWSPP 420
Query: 394 ESKAAEEKEFFDSHLAPFYRIEQLIIATLPESE----HGKPPS--------IVTDDNIEL 441
S++ EK +FD H PF+R EQ+I+ T PE + + PS I++ D +
Sbjct: 421 TSESRLEKAYFDEHFGPFFRTEQIIL-TAPERKPYNVTRQYPSEATTTYGGILSIDLLHQ 479
Query: 442 LFEIQEKVDEIRANYSG-LLVSLSDICLKPLG---EDCATQSILQYFQ----------MD 487
++Q+ V ++ + V+L DIC PL C +S+L YFQ MD
Sbjct: 480 ALDLQDAVVNLKVPFGNDSFVTLHDICYAPLAPQNTHCTIESVLNYFQNSHEKLDRVIMD 539
Query: 488 PDNFDNYGGVEHAEYCFQHYTSTET----------CFSAFKAPLEPTTALGGFSGNNYSE 537
P F + + E+ S T C + P+ P TALGG+ G+ ++
Sbjct: 540 PSQF--FIAADFHEHLLSCAGSPATLNDTTALHMPCMGTYGGPVFPWTALGGYEGDEFNM 597
Query: 538 ASAFIITYPVNNALTKVGDEN-GKAIAWEKAFIQLAK 573
A+ +IT+PV N +T GD KA+AWEKA+I L K
Sbjct: 598 ANVLVITFPVVNYIT--GDPKLEKAMAWEKAYIDLLK 632
>G3QQY7_GORGO (tr|G3QQY7) Uncharacterized protein OS=Gorilla gorilla gorilla
GN=NPC1 PE=4 SV=1
Length = 1238
Score = 197 bits (501), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 247/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME M+ + C+++
Sbjct: 197 ---DNGQAPFTITPVFSDFPVHGMEPMSNATKGCDESVDEVTAPCSCQDCSIVCGPKPQP 253
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ L + + + + + Y+ + V FG S P+ +
Sbjct: 254 PPPPAHWTI--LGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 312 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+Y+ V+L DICL PL C S+
Sbjct: 425 SGADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTHCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>G3SJE7_GORGO (tr|G3SJE7) Uncharacterized protein (Fragment) OS=Gorilla gorilla
gorilla GN=NPC1 PE=4 SV=1
Length = 1290
Score = 197 bits (500), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 247/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 33 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 87
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 88 VRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 147
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 148 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 207
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME M+ + C+++
Sbjct: 208 ---DNGQAPFTITPVFSDFPVHGMEPMSNATKGCDESVDEVTAPCSCQDCSIVCGPKPQP 264
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ L + + + + + Y+ + V FG S P+ +
Sbjct: 265 PPPPAHWTI--LGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 322
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 323 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 375
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 376 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYP 435
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+Y+ V+L DICL PL C S+
Sbjct: 436 SGADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTHCTILSV 495
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 496 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 555
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 556 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 603
>H2MTM9_ORYLA (tr|H2MTM9) Uncharacterized protein (Fragment) OS=Oryzias latipes
GN=LOC101159535 PE=4 SV=1
Length = 1271
Score = 197 bits (500), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 169/595 (28%), Positives = 252/595 (42%), Gaps = 78/595 (13%)
Query: 33 SRSIHSNEYCAMYDICGQRS-DGKVLNCPYPSPSV----KPHDLLSAKIQSLCPTIT-GN 86
SR +C Y CG GK NC Y P + + +DLL+ LCP GN
Sbjct: 15 SRCQVEAHHCIWYGECGDSPVPGKKFNCNYTGPPLPLEPEAYDLLT----ELCPGYDYGN 70
Query: 87 --VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
+CC QL+ + L CPAC N +NLFCEL+CSP+QS F T + D
Sbjct: 71 RSLCCNANQLRTLKGSLQLPLQFLSRCPACFYNLMNLFCELTCSPHQSQFTKATKFN--D 128
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFL--- 190
N V + Y+ +TF +Y+AC DV+ + N +A+ + G A N W ++
Sbjct: 129 SN--VMEVQYYIGKTFASAMYNACSDVQAPSSNVKALSLLCGKVAQECNATNWIQYMFST 186
Query: 191 --GQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCND-TSLGXXXXXXXXXXXXXX 247
GQ +P+ I+ + ++ S MN Y+C + G
Sbjct: 187 SNGQ--------APFPINPIFSDVEVSGFTPMNNKTYACTEGLEDGSGPCSCQDCTNACG 238
Query: 248 XXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPL 307
G V +++ + Y+ + V G + S P+
Sbjct: 239 PKPIPPVVPPPWTIFG---VDAMNVIMWFSYLSFLLVFLGAVLGAWCYRRRTVMSEYGPI 295
Query: 308 LVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
L S N G+ + E +F++ S+ +G + R P +V+ SL
Sbjct: 296 LDSNNPLSLNSDDLGQASPSCCETLGERFENFLRVLFSS----WGSFCVRNPFVVILGSL 351
Query: 368 AIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH 427
+V+ +GL + T P +LW P S+A +EK++FDSH PF+R QLII T ++
Sbjct: 352 LLVVAFSYGLRYMRITTDPVELWSSPASQARQEKDYFDSHFGPFFRTAQLIITTSTKNNF 411
Query: 428 GKPP----------SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---ED 474
P I + + + ++Q + + A Y G V+L DIC+ PL +
Sbjct: 412 TYSPYFGGSNVPFKPIFDKELLHQVLDLQLAIQSLVATYEGQNVTLKDICVAPLAPYNNN 471
Query: 475 CATQSILQYFQMDPDNFDNYGGVE---------HAEYC-----FQHYTST--ETCFSAFK 518
C SIL YFQ D+ G E H YC F T+ + C F
Sbjct: 472 CTILSILNYFQNSHSVLDHIAGDEFFTYADFHSHFLYCVSAPAFLKDTTLLHDPCLGTFG 531
Query: 519 APLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P+ P ALGG+ NY+ A+A +IT+P+NN L GK +AWEK FI K
Sbjct: 532 GPVFPWVALGGYDDTNYNNATALVITFPLNNYLND-SVRLGKVLAWEKEFIGFMK 585
>Q8MKD8_FELCA (tr|Q8MKD8) Niemann-Pick C1 OS=Felis catus PE=2 SV=1
Length = 1276
Score = 197 bits (500), Expect = 1e-47, Method: Compositional matrix adjust.
Identities = 165/589 (28%), Positives = 244/589 (41%), Gaps = 78/589 (13%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTEEQ 93
C Y CG S K NC Y P KP +DL +Q LCP ++CC +Q
Sbjct: 25 CIWYGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCDVQQ 79
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT----- 140
LQ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 80 LQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKT 139
Query: 141 -VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPP 196
V + Y+ E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 140 NVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFSK--- 196
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + C+ D G
Sbjct: 197 DNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPP 256
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ + ++ V + + Y+ + V FG S P+ +
Sbjct: 257 PVPWRILGLDAMYV-----IMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE D + + L + +G + R P ++ SLA +
Sbjct: 312 S-VNANDRGEASCCDALG------AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYP 424
Query: 434 VTDDN----------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D + + ++Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 SGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + KA WEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQKAHVWEKEFINFVK 592
>Q9N0Q0_FELCA (tr|Q9N0Q0) Niemann-Pick type C1 disease protein OS=Felis catus
GN=NPC1 PE=2 SV=1
Length = 1276
Score = 196 bits (499), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 165/589 (28%), Positives = 244/589 (41%), Gaps = 78/589 (13%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTEEQ 93
C Y CG S K NC Y P KP +DL +Q LCP ++CC +Q
Sbjct: 25 CIWYGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCDVQQ 79
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT----- 140
LQ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 80 LQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKT 139
Query: 141 -VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPP 196
V + Y+ E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 140 NVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFSK--- 196
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + C+ D G
Sbjct: 197 DNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPP 256
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ + ++ V + + Y+ + V FG S P+ +
Sbjct: 257 PVPWRILGLDAMYV-----IMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE D + + L + +G + R P ++ SLA +
Sbjct: 312 S-VNANDRGEASCCDALG------AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYP 424
Query: 434 VTDDN----------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D + + ++Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 SGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + KA WEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQKAHVWEKEFINFVK 592
>Q8MI49_FELCA (tr|Q8MI49) Mutant Niemann-Pick C1 OS=Felis catus PE=2 SV=1
Length = 1276
Score = 196 bits (499), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 165/589 (28%), Positives = 244/589 (41%), Gaps = 78/589 (13%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTEEQ 93
C Y CG S K NC Y P KP +DL +Q LCP ++CC +Q
Sbjct: 25 CIWYGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCDVQQ 79
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT----- 140
LQ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 80 LQTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKT 139
Query: 141 -VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPP 196
V + Y+ E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 140 NVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFSK--- 196
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + C+ D G
Sbjct: 197 DNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPP 256
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ + ++ V + + Y+ + V FG S P+ +
Sbjct: 257 PVPWRILGLDAMYV-----IMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE D + + L + +G + R P ++ SLA +
Sbjct: 312 S-VNANDRGEASCCDALG------AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYP 424
Query: 434 VTDDN----------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D + + ++Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 SGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + KA WEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQKAHVWEKEFINFVK 592
>R0KEG6_ANAPL (tr|R0KEG6) Niemann-Pick C1 protein (Fragment) OS=Anas
platyrhynchos GN=Anapl_02306 PE=4 SV=1
Length = 1259
Score = 196 bits (499), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 167/591 (28%), Positives = 246/591 (41%), Gaps = 81/591 (13%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSV----KPHDLLSAKIQSLCPTIT-GNV--CCTEEQL 94
C Y CG S K NC Y P + +DLL Q LCP + GNV CC QL
Sbjct: 6 CVWYGECGVASGDKRYNCAYDGPPIALPKDGYDLL----QELCPGLYFGNVSTCCDVLQL 61
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI------SQVDGNMT 140
Q + L CP+C N +NLFCEL+CSPNQS F+NVTS + +
Sbjct: 62 QTLKNNLQLPLQFLSRCPSCFYNLINLFCELTCSPNQSEFLNVTSTIPYYDPVTKENKSS 121
Query: 141 VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGAN---NYKEWFAFLGQKVPPG 197
+ + ++ E+F +Y+ACKDV+ + N +A+ + N W ++ K
Sbjct: 122 ITELQYFIGESFANAMYNACKDVEAPSSNVKALGLLCGKEVKDCNATNWIEYMFSK---D 178
Query: 198 FPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXX 254
+P+SI + + M MN + CN D S G
Sbjct: 179 NGQTPFSIIPIFSDVPVHGMNPMNNATKGCNESVDDSTGPCSCQDCSIVCGPKPQPPPLP 238
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+ ++ V + L I + V W S P+ + S
Sbjct: 239 APWLLFGLDAIYVIMWISYMGFLLIFFMLVFGIWCYRRRHFV-----SEYTPIDSNIAFS 293
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
+ DG++ +R E + L + ++G + R P V+ S+ + + C
Sbjct: 294 VNSHRDDGKITC--GERLGER----FENGLRMTFTSWGAFCVRNPRPVILFSVVFIAMCC 347
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG------ 428
G + T P LW P S+A +EKE+FD H PF+R EQLII P S+
Sbjct: 348 SGFVYIKATTNPVDLWSAPSSQARKEKEYFDKHFGPFFRSEQLIIQA-PNSQPDIYSPYP 406
Query: 429 -------KPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQ 478
PP +T + + + ++Q+ + I A++ V+L DICL PL +C
Sbjct: 407 SGADVPFGPP--LTKEILHQVLDLQDAIVNITASFDNETVTLKDICLAPLAPYNNNCTIL 464
Query: 479 SILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLE 522
S+L YFQ D+ G E H YC + S + C F P+
Sbjct: 465 SVLNYFQNSHSVLDHTVGDEFFVYADYHTHFLYCVRAPASLNDTSMLHDPCLGTFGGPVF 524
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ +NY+ A+A +IT PVNN + KA+AWEK FI K
Sbjct: 525 PWLVLGGYDADNYNNATALVITLPVNNYYND-SRKLMKALAWEKEFINFLK 574
>G1NCL6_MELGA (tr|G1NCL6) Uncharacterized protein (Fragment) OS=Meleagris
gallopavo GN=LOC100541908 PE=4 SV=2
Length = 1278
Score = 196 bits (497), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 166/592 (28%), Positives = 250/592 (42%), Gaps = 79/592 (13%)
Query: 40 EYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GNV--CCTEEQLQA 96
+ C Y CG S K NC Y P + + +Q LCP + GNV CC QLQ
Sbjct: 23 QQCVWYGECGIASGDKRYNCAYDGPPIALPEDGYDLMQELCPGLFFGNVSTCCDILQLQT 82
Query: 97 VP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTS-------ISQVDGNMTV 141
+ L CP+C N +NLFCEL+CSPNQS F+NVTS +S+ + ++
Sbjct: 83 LKNNLQLPLQFLSRCPSCFYNLINLFCELTCSPNQSEFLNVTSTIPYYDPVSK-ENKSSI 141
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPGF 198
+ ++ E F +Y+ACKDV+ + N +A+ + G A N W ++ K
Sbjct: 142 TELQYFIGERFANEMYNACKDVEAPSSNVKALGLLCGKDAKDCNATNWIEYMFSK---DN 198
Query: 199 PGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXXX 255
+P+SI + + M MN + CN D S G
Sbjct: 199 GQTPFSIIPIFSDVPVHGMNPMNNATKGCNESVDDSTGPCSCQDCSIVCGPKPQPPPLPV 258
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
+ + V + + + Y+ + V F + S P+ + S
Sbjct: 259 PWLLFGLDA-----VYIIMWISYMGFLLVFFALVFGVWCYRRRHFVSEYTPIDSNVAFSV 313
Query: 316 TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
+ +G++ +R E + L + ++G + R P V+ S+ + + C
Sbjct: 314 NSHHDNGKITC--GERLGER----FENGLRMTFTSWGAFCVRNPRPVILFSVVFIAMCCS 367
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
G + T P LW P S+A +EKE+FD H PF+R EQLII P S PSI +
Sbjct: 368 GFVYIKATTNPVDLWSAPSSQARKEKEYFDKHFGPFFRTEQLIIQA-PNSR----PSIYS 422
Query: 436 ---------------DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCAT 477
D + + ++Q + I A++ V L DIC+ PL +C
Sbjct: 423 PYPSGADVPFGPPLDKDILHQVLDLQNAIVNIVASFDNETVMLKDICVAPLAPYNNNCTI 482
Query: 478 QSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPL 521
S+L YFQ D+ G E H YC + S + C AF P+
Sbjct: 483 LSVLNYFQNSHSVLDHAVGDEFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGAFGGPV 542
Query: 522 EPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ G+NY+ A+A +IT PVNN + KA+AWEK F+ K
Sbjct: 543 FPWLVLGGYDGDNYNNATALVITLPVNNYYND-SKKIMKALAWEKEFVNFLK 593
>H0ZJN3_TAEGU (tr|H0ZJN3) Uncharacterized protein OS=Taeniopygia guttata GN=NPC1
PE=4 SV=1
Length = 1280
Score = 196 bits (497), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 160/582 (27%), Positives = 245/582 (42%), Gaps = 67/582 (11%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GNV--CCTEEQLQAVP 98
C Y CG S K NC Y P + + +Q LCP + GNV CC QLQ +
Sbjct: 27 CVWYGECGVASGDKRYNCAYDGPPIALPEDGYDLMQELCPGLFFGNVSTCCDVHQLQTLK 86
Query: 99 --------ILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVD-----GNMTVDGI 144
L CP+C N +NLFCEL+CSPNQS F+NVT +I D +V +
Sbjct: 87 NNLQLPLQFLSRCPSCFYNLINLFCELTCSPNQSDFLNVTNTIPYYDPVLKENKSSVTEL 146
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPGFPGS 201
++ + F +Y+ACKDV+ + N +A+ + G N W ++ K +
Sbjct: 147 QYFIGDRFANAMYNACKDVEAPSSNVKALGLLCGKDVKDCNATNWIEYMFSK---DNGQT 203
Query: 202 PYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXXXXXX 258
P++I + + M MN + CN D S G
Sbjct: 204 PFNIIPIFSDVPVHGMNPMNNATKGCNESMDDSTGPCSCQDCSIVCGPKPQPPPLPPPWL 263
Query: 259 XIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNL 318
+ ++ V + + Y+ + + F + S P+ + S +
Sbjct: 264 LFGLDAVYV-----IMWISYMGFLLIFFALVFGVWCYRRRHFVSEYTPIDSNVAFSVNSH 318
Query: 319 PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLL 378
+G + +R E + L + ++G + R P V+ S+ + + C G +
Sbjct: 319 RDNGNITC--GERLGER----FENGLRMTFTSWGAFCVRNPRPVILFSVVFIAMCCSGFV 372
Query: 379 RFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII----------ATLPESEHG 428
T P LW P S+A +EKE+FD+H PF+R EQ+II + P E
Sbjct: 373 YIKATTNPVDLWSAPSSQARKEKEYFDTHFGPFFRTEQVIIQAPKSHPDTYSPYPSGEDV 432
Query: 429 KPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQSILQYFQ 485
+T D + + ++Q+ + I A+Y V L DICL PL +C S+L YFQ
Sbjct: 433 PFGPPLTKDILHQVLDLQDAIVNITASYDNETVMLKDICLAPLAPYNNNCTILSVLNYFQ 492
Query: 486 MDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPTTALGG 529
D+ G E H YC + S ++C F P+ P LGG
Sbjct: 493 NSHSVLDHTVGDEFFVYADYHTHFLYCVRAPASLNDTSLLHDSCLGTFGGPVFPWLVLGG 552
Query: 530 FSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
+ +NY+ A+A +IT+PVNN + KA+AWEK FI
Sbjct: 553 YDDDNYNNATALVITFPVNNYYND-SKKLMKALAWEKEFINF 593
>F1NQT4_CHICK (tr|F1NQT4) Uncharacterized protein (Fragment) OS=Gallus gallus
GN=NPC1 PE=4 SV=2
Length = 1287
Score = 195 bits (496), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 166/593 (27%), Positives = 250/593 (42%), Gaps = 81/593 (13%)
Query: 40 EYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTIT-GNV--CCTEEQLQA 96
+ C Y CG S K NC Y P + +Q LCP + GNV CC QLQ
Sbjct: 32 QQCVWYGECGVASGDKRYNCAYDGPPIALPKGGYDLMQELCPGLFFGNVSTCCDILQLQT 91
Query: 97 VP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTS-------ISQVDGNMTV 141
+ L CP+C N +NLFCEL+CSPNQS F+NVTS +S+ + ++
Sbjct: 92 LKNNLQLPLQFLSRCPSCFYNLINLFCELTCSPNQSEFLNVTSTIPYYDPVSK-ENKSSI 150
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPGF 198
+ ++ E F +Y+ACKDV+ + N +A+ + G N W ++ K
Sbjct: 151 TELQYFIGERFANEMYNACKDVEAPSSNVKALGLLCGKDVKDCNATNWIEYMFNK---DN 207
Query: 199 PGSPYSIDFKTTILDSSP---MELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXX 252
+P+SI I +P M MN + CN D S G
Sbjct: 208 GQTPFSI---IPIFSDAPVHGMNPMNNATKGCNESVDDSTGPCSCQDCSIVCGPKPQPPP 264
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
+ + V + + + Y+ + + F + S P+ +
Sbjct: 265 LPAPWLLFGLDA-----VYIIMWISYMGFLLIFFALVFGVWCYRRRHFVSEYTPIDSNVA 319
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
S + +G++ +R E + L + ++G + R P V+ S+ + +
Sbjct: 320 FSANSHRDNGKITC--GERLGER----FENGLRMTFTSWGAFCVRNPRPVILFSVVFIAM 373
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHG---- 428
C G + T P LW P S+A +EKE+FD H PF+R EQLII P S
Sbjct: 374 CCSGFVYIKATTNPVDLWSAPSSQARKEKEYFDKHFGPFFRTEQLIIQA-PNSHPDIYSP 432
Query: 429 ---------KPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLG---EDCA 476
PP + D + + ++Q+ + I A++ V+L DICL PL +C
Sbjct: 433 YPSGADVPFGPP--LNKDILHQVLDLQDAIVNIAASFDNETVTLKDICLAPLAPYNNNCT 490
Query: 477 TQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAP 520
S+L YFQ D+ G + H YC + S + C AF P
Sbjct: 491 ILSVLNYFQNSHSVLDHSVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGAFGGP 550
Query: 521 LEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+ P LGG+ G+NY+ A+A +IT PVNN + KA+AWEK FI K
Sbjct: 551 VFPWLVLGGYDGDNYNNATALVITLPVNNYYND-SKKIMKALAWEKEFINFLK 602
>M3VUX6_FELCA (tr|M3VUX6) Uncharacterized protein OS=Felis catus GN=NPC1 PE=4
SV=1
Length = 1276
Score = 195 bits (496), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 164/589 (27%), Positives = 244/589 (41%), Gaps = 78/589 (13%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCTEEQ 93
C Y CG S K NC Y P KP +DL +Q LCP ++CC +Q
Sbjct: 25 CIWYGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCDVQQ 79
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT----- 140
L+ + L CP+C N +NLFCEL+CSP QS F+NVT+ +T
Sbjct: 80 LRTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKT 139
Query: 141 -VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPP 196
V + Y+ E+F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 140 NVKELQYYIGESFANAMYNACRDVEAPSSNDKALGLLCGKDAEACNATNWIEYMFSK--- 196
Query: 197 GFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L + ME MN + C+ D G
Sbjct: 197 DNGQAPFTITPIFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSIVCGPKPQPPPP 256
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ + ++ V + + Y+ + V FG S P+ +
Sbjct: 257 PVPWRILGLDAMYV-----IMWITYMAFLLVFFGAFFALWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE D + + L + +G + R P ++ SLA +
Sbjct: 312 S-VNANDRGEASCCDALG------AAFEGCLRRLFSQWGSFCVRNPGPIIFFSLAFIAAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII S H P
Sbjct: 365 SSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTSAHTYQPYP 424
Query: 434 VTDDN----------IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D + + ++Q ++ I A+Y+ V+L DIC+ PL ++C S+
Sbjct: 425 SGSDVPFGPPLDLAILHQVLDLQTAIENITASYNNETVTLQDICVAPLSPYNKNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSMLDHEIGDDFFVYADYHTHLLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN + KA WEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-ERLQKAHVWEKEFINFVK 592
>H2QEC5_PANTR (tr|H2QEC5) Uncharacterized protein OS=Pan troglodytes GN=NPC1 PE=4
SV=1
Length = 1277
Score = 195 bits (496), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 247/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME MN + C+++
Sbjct: 197 ---DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKP 251
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
L + + + + + Y+ + V FG S P+ +
Sbjct: 252 QPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 312 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 365 SSGLVFVWVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+ + V+L DICL PL +C S+
Sbjct: 425 SGADVPFGPPLDIQILHQVLDLQIAIENITASSNNETVTLQDICLAPLSPYNTNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>K7BF17_PANTR (tr|K7BF17) Niemann-Pick disease, type C1 OS=Pan troglodytes
GN=NPC1 PE=2 SV=1
Length = 1277
Score = 195 bits (496), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 169/589 (28%), Positives = 247/589 (41%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME MN + C+++
Sbjct: 197 ---DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKP 251
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
L + + + + + Y+ + V FG S P+ +
Sbjct: 252 QPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 312 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 365 SSGLVFVWVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYP 424
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+ + V+L DICL PL +C S+
Sbjct: 425 SGADVPFGPPLDIQILHQVLDLQIAIENITASSNNETVTLQDICLAPLSPYNTNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>F7DIC2_MACMU (tr|F7DIC2) Uncharacterized protein (Fragment) OS=Macaca mulatta
PE=4 SV=1
Length = 1278
Score = 193 bits (491), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 170/587 (28%), Positives = 247/587 (42%), Gaps = 74/587 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPY---PSPSVKP-HDLLSAKIQSLCPTIT-GNV--CCTE 91
++ C Y CG K NC Y P P K +DL +Q LCP GNV CC
Sbjct: 29 SQSCVWYGECGIAYGDKRYNCEYFGPPKPLPKDGYDL----VQELCPGFFFGNVSLCCDV 84
Query: 92 EQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT--- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 85 QQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQT 144
Query: 141 ---VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGANNYKEWFAF-LGQKVP 195
V + +V ++F +Y+AC+DV+ + N +A+ + G A+ F LG +
Sbjct: 145 KTNVKELQYFVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADVLCISVGFSLGLNL- 203
Query: 196 PGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXX 255
YS F ME MN + C+++
Sbjct: 204 -------YSTQFLPVDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKPQP 254
Query: 256 XXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSF 315
L + + + + + Y+ + V FG S P+ + S
Sbjct: 255 PPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAFS- 313
Query: 316 TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
N GE DP V +F + L + +G + R P V+ SL + +
Sbjct: 314 VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFIAVCSS 367
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 368 GLVFVRVTTNPIDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTYQPYPSG 427
Query: 436 DD-------NIELL---FEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSILQ 482
D +I++L ++Q ++ I A+Y+ V+L DICL PL +C S+L
Sbjct: 428 ADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCTIMSVLN 487
Query: 483 YFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTTA 526
YFQ D+ G + H YC + S + C F P+ P
Sbjct: 488 YFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLV 547
Query: 527 LGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI L +
Sbjct: 548 LGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINLVR 593
>Q6BT03_DEBHA (tr|Q6BT03) DEHA2D04620p OS=Debaryomyces hansenii (strain ATCC
36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
GN=DEHA2D04620g PE=4 SV=2
Length = 1264
Score = 193 bits (490), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 145/558 (25%), Positives = 246/558 (44%), Gaps = 53/558 (9%)
Query: 36 IHSNEYCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI--TGNVCCTEE 92
+H + +CAMYD CG++S G L C + +VKP + +C VCC+E+
Sbjct: 22 VHEDGFCAMYDNCGKKSLFGSELPCVNNTEAVKPSKGSIEILNRICGADFPMERVCCSEK 81
Query: 93 QL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNM-TVD 142
QL + P++ CPAC +NF + FC+ +CS NQS FI++T S+ +D V
Sbjct: 82 QLLNLESNLKKVDPLISSCPACRKNFYDFFCKFTCSSNQSTFIDITKTSESIDQKKEIVT 141
Query: 143 GIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSP 202
+ +V + +++CK+VKF N A+D +G GA NYK++ FLG + P GSP
Sbjct: 142 ELSQFVDSDYASEFFNSCKEVKFSATNGYAMDLIGGGATNYKDFLKFLGDE-KPLLGGSP 200
Query: 203 YSIDFKTTILDSSPME---LMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
+ I+++ + + L + + SC+D
Sbjct: 201 FQINYEYATTERQQNDGIILRSGDMKSCDDKDYKCACSDCSNSCPKLPGFKSYDKKCTIG 260
Query: 260 IKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLL-------VSEG 312
+ + C ++ +L+ L+ +L G+ + L+ V
Sbjct: 261 V------LPCFSFAIIILWGCLILILGGYHISIVRSKKNDTRRWSNSLIDDDDDDDVGNT 314
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
FT + V++ + Y + + G + A P I + + + +
Sbjct: 315 YHFTRNSNSSSLAVLEEYHMKLIGY------IQTGFEYIGYYCASLPGITIGVCIVVTLF 368
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
+ GL ++E P LWV PE A + +FF+ ++RIEQ+II++ ES+
Sbjct: 369 MSSGLFWLSLEINPINLWVSPEEPALKNLQFFEQEFGEWFRIEQIIISSSNESQ-----P 423
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSG--LLVSLSDICLKPLGEDCATQSILQYFQMDPDN 490
I+ +NI+ F EK E+R+ G L+D+C KP+G+DCA +S QYFQ D N
Sbjct: 424 ILNWENIQWWF---EKEQELRSLTIGDDENFGLTDLCFKPMGDDCAIESFAQYFQGDIKN 480
Query: 491 FDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNA 550
+ + C S C F+ PL+ F + ++ AF+IT +NN
Sbjct: 481 LKEDNWKQQLKSCTD---SPVNCLPTFQQPLKKNLL---FDKEDIFDSKAFVITLLINNN 534
Query: 551 LTKVGDENGKAIAWEKAF 568
+ + + A+ +E A
Sbjct: 535 SSNI-EYTSNAVEYEHAL 551
>K7FH26_PELSI (tr|K7FH26) Uncharacterized protein (Fragment) OS=Pelodiscus
sinensis GN=NPC1 PE=4 SV=1
Length = 1278
Score = 192 bits (489), Expect = 2e-46, Method: Compositional matrix adjust.
Identities = 164/588 (27%), Positives = 254/588 (43%), Gaps = 75/588 (12%)
Query: 42 CAMYDICGQRSDGKVLNCPY---PSPSVKP-HDLLSAKIQSLCPTI---TGNVCCTEEQL 94
C Y CG S K NC Y P P K +DL+ Q LCP + +VCC +QL
Sbjct: 26 CVWYGECGIASADKRYNCKYTGLPIPLPKDGYDLM----QELCPGLFFDNVSVCCDVQQL 81
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVD-----GNMT 140
Q + L CP+C N +NLFCEL+CSP+Q F+NVT +I D +
Sbjct: 82 QTLKNNLQLPLQFLSRCPSCFYNLINLFCELTCSPHQVHFLNVTKTIPYYDPVTKENKTS 141
Query: 141 VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPG 197
+ ++ Y+ E+F +Y+ACKDV+ + N +A+ + G N W ++ K
Sbjct: 142 ITELEYYIGESFANAMYNACKDVEAPSSNDKALGLLCGKDVKDCNATNWIQYMFSKENGQ 201
Query: 198 FPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXX 257
+P+SI + + M MN + CN+++
Sbjct: 202 ---TPFSIIPFFSDISLHGMSPMNNATKGCNESTDDVTGPCSCQDCSIVCGPKPEPPPPA 258
Query: 258 XXIKMGSLKVRCVDLSLAVLYIVLVF--VLFG-WIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+ L V + ++ + +LVF V+FG W + R
Sbjct: 259 APWLLLGLDAIYVIMWISYMGFLLVFFAVIFGVWCYRKRHFVSEYTPIDSNIAFSVNSRH 318
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
+ GE L + +N ++ +F+ ++G + R P V+ S+ V + C
Sbjct: 319 DSGEASCGERL--GERFENCLRLTFM---------SWGAFCVRNPRPVVLFSVVFVAMCC 367
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIV 434
GL+ + T P LW P S+A +EK++FD++ PF+R EQLII H P
Sbjct: 368 SGLMYIKITTNPVDLWSSPNSQARKEKQYFDTYFGPFFRTEQLIIRAPHSKPHIYSPYPS 427
Query: 435 TDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQSIL 481
+D + ++L+++ Q ++ I A+Y V L DICL PL +C S+L
Sbjct: 428 GNDVPFGPPLDKDILYQVLDLQNAIENITASYDNETVMLKDICLAPLAPYNNNCTILSVL 487
Query: 482 QYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTT 525
YFQ ++ G E H YC + S + C F P+ P
Sbjct: 488 NYFQNSYSVLNHSVGDEFFVFADYHTHFLYCVRAPASLNDTSQLHDPCLGTFGGPVFPWL 547
Query: 526 ALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ G NY+ A+A +IT+PV N + +A+AWEK FI K
Sbjct: 548 VLGGYDGENYNNATALVITFPVRNYYNDT-HKLMRALAWEKEFISFVK 594
>K7DIM3_PANTR (tr|K7DIM3) Niemann-Pick disease, type C1 OS=Pan troglodytes
GN=NPC1 PE=2 SV=1
Length = 1277
Score = 192 bits (488), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 170/589 (28%), Positives = 249/589 (42%), Gaps = 72/589 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 22 SQSCVWYGECGIAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFGNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 136
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV ++F +Y+AC+DV+ + N +A+ + A A N W ++ K
Sbjct: 137 TKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCGKDADACNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + ME MN + C+++
Sbjct: 197 ---DNGQAPFTITPVFSDFPVHGMEPMNNATKGCDESV--DEVTAPCSCQDCSIVCGPKP 251
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
L + + + + + Y+ + V FG S P+ +
Sbjct: 252 QPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVSEYTPIDSNIAF 311
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
S N GE DP V +F + L + +G + R P V+ SL +
Sbjct: 312 S-VNASDKGEASCCDP-----VSAAF-EGCLRRLFTRWGSFCVRNPGCVIFFSLVFITAC 364
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII-ATLPESEHGKPPS 432
GL+ V T P LW P S+A EKE+FD H PF+R EQLII A L + +P
Sbjct: 365 SSGLVFVWVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKPTYQPYP 424
Query: 433 IVTDD------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D +I++L ++ Q ++ I A+ + V+L DICL PL +C S+
Sbjct: 425 SGADVPFGPPLDIQILHQVLDLQIAIENITASSNNETVTLQDICLAPLSPYNTNCTILSV 484
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 485 LNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 544
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI K
Sbjct: 545 LVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVK 592
>F2QMI3_PICP7 (tr|F2QMI3) Niemann-Pick C1 protein OS=Komagataella pastoris
(strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL
Y-11430 / Wegner 21-1) GN=NPC1 PE=4 SV=1
Length = 1284
Score = 192 bits (487), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 150/556 (26%), Positives = 252/556 (45%), Gaps = 48/556 (8%)
Query: 36 IHSNEYCAMYDICGQRSD-GKVLNCP---YPSPSV-KPHDLLSAKIQSLCPTITGNVCCT 90
+H CA+ CG+++ G L CP + +PS DLL I CC
Sbjct: 21 VHEAGICALRGNCGKKNFFGSELPCPDNTFSTPSSPDDFDLLEQICGKEFADINTYTCCD 80
Query: 91 -------EEQLQAV-PILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVDGNMTV 141
++QL+ V PI+ CPAC NF LFC +CSP+QS F+NVT ++ G V
Sbjct: 81 TSQLLNLQKQLKKVDPIIASCPACRSNFYTLFCSFTCSPDQSQFVNVTDTVKSTTGEDAV 140
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGS 201
+D Y+ ++ E +++CKD+KFG N A+D +G GA NY ++ FLG + P GS
Sbjct: 141 SELDYYIQSSWAEEFFNSCKDIKFGASNGYAMDLIGGGAKNYSDFLKFLGDE-KPLLGGS 199
Query: 202 PYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
P+ I+F+ +S+P +E + V +CND++
Sbjct: 200 PFQINFQYPS-NSTPQWVEYPDNPVRACNDSN---PDYKCACSDCPGSCPVLPSRHAPKQ 255
Query: 260 IKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLP 319
++G L C ++ VLY + VL G+I S ++ S +
Sbjct: 256 CRVGILP--CFSFAVVVLYAI---VLLGYIAYKTSRYTKSRTSLLLHDDLALDESRYDYS 310
Query: 320 KDGEVLVIDPQRQNEVQY---SFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
+ E + N Y S ++EW G + + P V+ SL + + L
Sbjct: 311 SEDEQFFNNEFEYNSSYYPINSKLEEWFCKL----GFFCSTSPKTVIFVSLVVSLTLTSF 366
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
+ +E P KLWV P+++A ++K+ FD PFYR +Q+ + +E G +++
Sbjct: 367 MRFIELEEDPVKLWVSPQAEAFQQKQVFDEKFGPFYRTQQIFVI----NETGP---VLSY 419
Query: 437 DNIELLFEIQEKVDEIRAN---YSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDN 493
D ++ F+ + + ++AN Y ++L D+CLKP+ + C +S QYF D +
Sbjct: 420 DTLKWWFDKESTILSLQANASDYQRETITLQDLCLKPINDACVVESFTQYFGGDSSSLTE 479
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYS--EASAFIITYPVNNAL 551
+ C S C +F+ PL+ + G ++ +++A +IT +NN+
Sbjct: 480 DNWEKKLSSC---ANSPVNCLPSFQQPLKKSLLFGTEQLEDFDILKSNALVITLVMNNSN 536
Query: 552 TKVGDENGKAIAWEKA 567
+ ++AWEK
Sbjct: 537 DVNSTQFQNSLAWEKV 552
>C4QWB0_PICPG (tr|C4QWB0) Vacuolar membrane protein that transits through the
biosynthetic vacuolar protein sorting pathway
OS=Komagataella pastoris (strain GS115 / ATCC 20864)
GN=PAS_chr1-1_0168 PE=4 SV=1
Length = 1284
Score = 192 bits (487), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 150/556 (26%), Positives = 252/556 (45%), Gaps = 48/556 (8%)
Query: 36 IHSNEYCAMYDICGQRSD-GKVLNCP---YPSPSV-KPHDLLSAKIQSLCPTITGNVCCT 90
+H CA+ CG+++ G L CP + +PS DLL I CC
Sbjct: 21 VHEAGICALRGNCGKKNFFGSELPCPDNTFSTPSSPDDFDLLEQICGKEFADINTYTCCD 80
Query: 91 -------EEQLQAV-PILVGCPACLRNFLNLFCELSCSPNQSLFINVT-SISQVDGNMTV 141
++QL+ V PI+ CPAC NF LFC +CSP+QS F+NVT ++ G V
Sbjct: 81 TSQLLNLQKQLKKVDPIIASCPACRSNFYTLFCSFTCSPDQSQFVNVTDTVKSTTGEDAV 140
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGS 201
+D Y+ ++ E +++CKD+KFG N A+D +G GA NY ++ FLG + P GS
Sbjct: 141 SELDYYIQSSWAEEFFNSCKDIKFGASNGYAMDLIGGGAKNYSDFLKFLGDE-KPLLGGS 199
Query: 202 PYSIDFKTTILDSSP--MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
P+ I+F+ +S+P +E + V +CND++
Sbjct: 200 PFQINFQYPS-NSTPQWVEYPDNPVRACNDSN---PDYKCACSDCPGSCPVLPSRHAPKQ 255
Query: 260 IKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLP 319
++G L C ++ VLY + VL G+I S ++ S +
Sbjct: 256 CRVGILP--CFSFAVVVLYAI---VLLGYIAYKTSRYTKSRTSLLLHDDLALDESRYDYS 310
Query: 320 KDGEVLVIDPQRQNEVQY---SFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFG 376
+ E + N Y S ++EW G + + P V+ SL + + L
Sbjct: 311 SEDEQFFNNEFEYNSSYYPINSKLEEWFCKL----GFFCSTSPKTVIFVSLVVSLTLTSF 366
Query: 377 LLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTD 436
+ +E P KLWV P+++A ++K+ FD PFYR +Q+ + +E G +++
Sbjct: 367 MRFIELEEDPVKLWVSPQAEAFQQKQVFDEKFGPFYRTQQIFVI----NETGP---VLSY 419
Query: 437 DNIELLFEIQEKVDEIRAN---YSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDN 493
D ++ F+ + + ++AN Y ++L D+CLKP+ + C +S QYF D +
Sbjct: 420 DTLKWWFDKESTILSLQANASDYQRETITLQDLCLKPINDACVVESFTQYFGGDSSSLTE 479
Query: 494 YGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYS--EASAFIITYPVNNAL 551
+ C S C +F+ PL+ + G ++ +++A +IT +NN+
Sbjct: 480 DNWEKKLSSC---ANSPVNCLPSFQQPLKKSLLFGTEQLEDFDILKSNALVITLVMNNSN 536
Query: 552 TKVGDENGKAIAWEKA 567
+ ++AWEK
Sbjct: 537 DVNSTQFQNSLAWEKV 552
>L8IF09_BOSMU (tr|L8IF09) Niemann-Pick C1 protein (Fragment) OS=Bos grunniens
mutus GN=M91_00536 PE=4 SV=1
Length = 1294
Score = 191 bits (486), Expect = 5e-46, Method: Compositional matrix adjust.
Identities = 166/595 (27%), Positives = 247/595 (41%), Gaps = 84/595 (14%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTIT-GNV--CCT 90
++ C Y CG S K NC Y P KP +DL +Q LCP GNV CC
Sbjct: 33 SQSCIWYGECGIASGDKRYNCRYSGPP-KPLPQDGYDL----VQELCPGFFFGNVSLCCD 87
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VD----- 136
+QL + L CP+C N +NLFCEL+CSP QS F+NVT+ VD
Sbjct: 88 VQQLHTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPATNQ 147
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
V + YV E+F +Y++C+DV+ + N +A+ + A A N W ++ K
Sbjct: 148 TKTNVKELQYYVGESFANAMYNSCRDVEAPSSNEKALGLLCGREASACNATNWIEYMFNK 207
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXX 250
+P++I + L + ME MN + C+ D G
Sbjct: 208 ---DNGQAPFTITPVFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQP 264
Query: 251 XXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
+ + ++ V + Y+ + V FG S P+ +
Sbjct: 265 PPPPVPWRILGLDAMYV-----IMWSTYMAFLLVFFGAFFAVWCYRKRYFVSEFTPIDGN 319
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
S K G E + EW +G + R P V+ S+A +
Sbjct: 320 IPFSINASDKGGPTCCDPLGAAFEAHLRRLFEW-------WGSFCVRHPGCVVFFSVAFI 372
Query: 371 ILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH--- 427
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H
Sbjct: 373 AACSSGLVFIQVTTDPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIRAPHTPPHIYE 432
Query: 428 ----------GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GED 474
G P ++ D + + ++Q ++ I A+Y+ V+L DIC+ PL ++
Sbjct: 433 PYPSGADVPFGPPLAV---DILHQVLDLQTAIESITASYNNETVTLRDICVAPLSPYNQN 489
Query: 475 CATQSILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFK 518
C S+L YFQ D+ G + H YC + S + C F
Sbjct: 490 CTILSVLNYFQNSHSVLDHQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFG 549
Query: 519 APLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P+ P LGG+ NY+ A+A +IT+PVNN ++ +A AWE+ FI +
Sbjct: 550 GPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEREFINFVQ 603
>B0JYK2_BOVIN (tr|B0JYK2) NPC1 protein OS=Bos taurus GN=NPC1 PE=2 SV=1
Length = 1277
Score = 191 bits (484), Expect = 9e-46, Method: Compositional matrix adjust.
Identities = 164/591 (27%), Positives = 244/591 (41%), Gaps = 76/591 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVK-PHDLLSAKIQSLCPTIT-GNV--CCTEEQL 94
++ C Y CG S K NC Y P P D +Q LCP GNV CC +QL
Sbjct: 22 SQSCIWYGECGIASGDKRYNCRYSGPPEPLPQDGYDL-VQELCPGFFFGNVSLCCDVQQL 80
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VD-----GNMT 140
+ L CP+C N +NLFCEL+CSP QS F+NVT+ VD
Sbjct: 81 HTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPATNQTKTN 140
Query: 141 VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPPG 197
V + YV E+F +Y++C+DV+ + N +A+ + A A N W ++ K
Sbjct: 141 VKELQYYVGESFANAMYNSCRDVEAPSSNEKALGLLCGREASACNATNWIEYMFNK---D 197
Query: 198 FPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXX 254
+P++I + L + ME MN + C+ D G
Sbjct: 198 NGQAPFTITPVFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQPPPPP 257
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+ + ++ V + Y+ + V FG S P+ + S
Sbjct: 258 VPWRILGLDAMYV-----IMWSTYMAFLLVFFGAFFAVWCYRKRYFVSEFTPIDGNIPFS 312
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
K G E + EW +G + R P V+ S+A +
Sbjct: 313 INASDKGGPTCCDPLGAAFEAHLRRLFEW-------WGSFCVRHPGCVVFFSVAFIAACS 365
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH------- 427
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H
Sbjct: 366 SGLVFIQVTTDPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIRAPHTPPHIYEPYPS 425
Query: 428 ------GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQ 478
G P ++ D + + ++Q ++ I A+Y+ V+L DIC+ PL ++C
Sbjct: 426 GADVPFGPPLAV---DILHQVLDLQTAIESITASYNNETVTLRDICVAPLSPYNQNCTIL 482
Query: 479 SILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLE 522
S+L YFQ D+ G + H YC + S + C F P+
Sbjct: 483 SVLNYFQNSHSVLDHQVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVF 542
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A AWE+ FI +
Sbjct: 543 PWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEREFINFVQ 592
>J9VSE9_CRYNH (tr|J9VSE9) Vacuolar membrane protein OS=Cryptococcus neoformans
var. grubii serotype A (strain H99 / ATCC 208821 / CBS
10515 / FGSC 9487) GN=CNAG_02298 PE=4 SV=1
Length = 1334
Score = 191 bits (484), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 154/551 (27%), Positives = 241/551 (43%), Gaps = 69/551 (12%)
Query: 42 CAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCP---TITGNVCCTEEQL--- 94
CAM CG+ S G L CP S + P L + S+C ++ +VCCT QL
Sbjct: 15 CAMRGTCGKTSMFGADLPCPDDSDATVPDQSLLDLMASVCGPSYSLPDHVCCTYNQLSTL 74
Query: 95 -----QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGIDLYV 148
QA P++ CPAC+ NF + +C+ +CSP+QS F++VT+ + +G V +D V
Sbjct: 75 SDRLQQAAPLIASCPACINNFRSFYCDFTCSPDQSTFLSVTATQKTTEGKDAVKEVDYEV 134
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFK 208
+ F +G Y++CKDV+FG N A+D +G GA N + ++G + PG GSP+ I+F
Sbjct: 135 SSDFKQGFYNSCKDVQFGATNGFAMDLIGGGATNASGFLKYMGD-LRPGL-GSPFQINFP 192
Query: 209 TTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVR 268
D+ A + SC+D +G+ V
Sbjct: 193 ----DNDDSAYRRAPL-SCSDAEDINARCACADCPSVCPSLPYIAPPSTRQCHVGA--VS 245
Query: 269 CVDLSLAVLYIVLVFV---LFGWIXXXXXXXXX-----------------XXGSSAEPLL 308
C+ SL ++Y V++ V L+ W GS + L+
Sbjct: 246 CLTFSLLIIYSVIILVGALLYIWKQAARHRQRRYERVALLDPPHSPTIQNGQGSGLDGLM 305
Query: 309 VS--------EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPT 360
G L + +L DP + + + I L F+ G A+RP
Sbjct: 306 GRNDDAESGPSGSIHFRLGRGASLL--DPMEHLQPKQNKINATLRRFFYRLGLTCAKRPI 363
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
V + IV LL FG F VET P +LWV P S++A +K FFD FY+ EQ+ I
Sbjct: 364 EVFAITALIVGLLNFGWKYFEVETDPVRLWVSPTSESASQKRFFDDSFGSFYKSEQVFIT 423
Query: 421 TLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED--CATQ 478
G P V D ++ +++ +++ ++ + + L DIC P G+ C Q
Sbjct: 424 ----QSSGSP---VNYDTLDWWLKVETEINALKTSDG---IGLEDICFAPAGKGTPCVIQ 473
Query: 479 SILQYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEA 538
S+ + D + + G E C F P++P LGG +G ++ +A
Sbjct: 474 SVSAWLGDDMEVW----GEEWESRVSDCAARPGECLPPFGQPIDPKLVLGGANG-DWLKA 528
Query: 539 SAFIITYPVNN 549
A ++T+ VNN
Sbjct: 529 KALVVTWVVNN 539
>H0V7B5_CAVPO (tr|H0V7B5) Uncharacterized protein (Fragment) OS=Cavia porcellus
GN=LOC100718604 PE=4 SV=1
Length = 1267
Score = 191 bits (484), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 161/587 (27%), Positives = 249/587 (42%), Gaps = 82/587 (13%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C + CG S K NC Y P KP +DL +Q LCP ++CC
Sbjct: 22 SQSCIWFGECGIASGDKRYNCKYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCD 76
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV---DGNM 139
+QLQ + L CP+C N +NLFCEL+CSP+QS F+NVT+ D N
Sbjct: 77 VQQLQTLKDNLQLPLQFLSRCPSCFYNLMNLFCELTCSPHQSQFLNVTATEDYIDPDTNQ 136
Query: 140 T---VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQK 193
T V + Y+ ++F +Y+AC+DV+ + N +A+ + A N W ++ K
Sbjct: 137 TRTNVKELQYYIGQSFANAMYNACRDVEAPSSNDKALGLLCGRDADTCNATNWIEYMFNK 196
Query: 194 VPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXX 253
+P++I + L ME M + +CN++
Sbjct: 197 ---DNGQAPFTITPIFSDLPIHGMEPMRNATKACNES------------VDEVTGPCSCQ 241
Query: 254 XXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGR 313
+ L + + + + Y+ + V FG S P+ +
Sbjct: 242 DCSIVCVPWRLLGWDAMYVIMWITYMAFLVVFFGACFAVWCYRKRYFVSEYTPIDSNMAL 301
Query: 314 SFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
+ GE+ DP + + L + + +G + +RP V+ SL +
Sbjct: 302 G-GDTSDKGEIACCDPLG------TCFEGCLRHLFTRWGAFCVQRPGYVIFFSLVFIASC 354
Query: 374 CFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSI 433
GL+ + T P LW P S+A EKE+FD+H PF+R EQLII +H P
Sbjct: 355 SSGLVFVRLTTNPVDLWSAPSSQARLEKEYFDTHFGPFFRTEQLIIQAPHTGKHPYSPYP 414
Query: 434 VTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSI 480
D + E+L ++ Q ++ I A Y+ V+L DICL PL ++C S+
Sbjct: 415 SGADVPFGPPLDKEILHQVLDLQIAIENITAYYNNETVTLGDICLAPLSPYNKNCTIFSV 474
Query: 481 LQYFQMDPDNFDNYGGVE---------HAEYCFQHYTS-------TETCFSAFKAPLEPT 524
L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 475 LNYFQNSHATLDHIVGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPW 534
Query: 525 TALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI
Sbjct: 535 LVLGGYDDQNYNNATALVITFPVNNYYDD-PEKLQRAQAWEKEFIHF 580
>Q2U2G2_ASPOR (tr|Q2U2G2) Cholesterol transport protein OS=Aspergillus oryzae
(strain ATCC 42149 / RIB 40) GN=AO090038000467 PE=4 SV=1
Length = 1163
Score = 190 bits (483), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 145/473 (30%), Positives = 217/473 (45%), Gaps = 39/473 (8%)
Query: 107 LRNFLNLFCELSCSPNQSLFINVTSIS-QVDGNMTVDGIDLYVTETFGEGLYSACKDVKF 165
L NF N+FC +CSP+QSLF+NVT G V +D +E + G Y +CK+VK
Sbjct: 4 LENFFNIFCTFTCSPDQSLFLNVTETEPSSSGKSLVTELDNIWSEEYQSGFYESCKNVKN 63
Query: 166 GTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP--MELMNAS 223
G +A+DF+G GA +Y + FLG K GSP+ I+FKT P M +
Sbjct: 64 GASGGKAMDFIGGGAKDYTHFLKFLGDK---KLLGSPFQINFKTEPAGPDPQGMHPLPIK 120
Query: 224 VYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVF 283
+CND+ +G L LS AV+ I VF
Sbjct: 121 PKACNDSD---EAFRCSCVDCPDVCPQLPAVETDKQCHVGLLPC----LSFAVILIYSVF 173
Query: 284 VLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEW 343
+LF E + + + + ++ +G+++ + +
Sbjct: 174 LLFVVALSSYFTYKERRHRKPERVRLLQDPTPSDDEDEGDIVHAGGYLEQPKGVYKLNSV 233
Query: 344 LSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEF 403
L + + G AR P + + SS+ V LL G LRF VET P +LWV P S A +EK++
Sbjct: 234 LDSVFSQIGGTCARFPAVTIVSSIIAVGLLSLGWLRFAVETDPVRLWVSPTSAAFQEKQY 293
Query: 404 FDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSL 463
FD++ PFYR EQ + ++ G ++T D + F+++ +V + + G++ L
Sbjct: 294 FDANFGPFYRAEQAFLV----NDSGP---VLTYDTLSWWFDVESRVRRMISLDRGII--L 344
Query: 464 SDICLKPLGEDCATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFK 518
DIC KP G+ C QS+ YF +DPD + E +C + C F
Sbjct: 345 DDICFKPTGDVCVVQSVTGYFGGSMYNLDPDTWK-----ERVRHCAES-PGDVNCLPEFG 398
Query: 519 APLEPTTALGGF--SGNNYSEASAFIITYPVNNALTKVGDEN-GKAIAWEKAF 568
PL+P LGG+ SG+ + +A A I T+ VNN G EN AI WE +F
Sbjct: 399 QPLKPEMILGGYEESGDVF-DARALIATWVVNNHAQ--GTENEANAIDWEDSF 448
>H3BC01_LATCH (tr|H3BC01) Uncharacterized protein (Fragment) OS=Latimeria
chalumnae PE=4 SV=1
Length = 1279
Score = 190 bits (482), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 170/610 (27%), Positives = 254/610 (41%), Gaps = 78/610 (12%)
Query: 18 LILSWFSPSLTAAQISRSIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQ 77
+ L F+P + A+ R I E C D +R + P P P + +DL +Q
Sbjct: 11 IFLMQFTPPMACAE--RCIWYGE-CETVDGTEKRYNCNYTGAPVPLPH-EGYDL----VQ 62
Query: 78 SLCPTI-TGNV--CCTEEQLQAVPI--------LVGCPACLRNFLNLFCELSCSPNQSLF 126
LCP GNV CC +QL+ + + L CP+C N +NLFCEL+CSP+QS F
Sbjct: 63 ELCPGFFYGNVSLCCDIQQLKTLKVNLQLPLQFLSRCPSCFYNLMNLFCELTCSPHQSQF 122
Query: 127 INVTSISQV------DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAG 179
+N T + V + Y+ + F + +Y+ACKDV+ + N +A+ + G
Sbjct: 123 VNATKFKTYFDPVAKENKTDVIEVKYYIGQRFADAMYNACKDVEAPSSNEKALGLLCGKD 182
Query: 180 AN--NYKEWFAFL----GQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLG 233
A N W ++ + P FP P D T M MN + CN+++
Sbjct: 183 AKDCNATNWIQYMFNTDNSQTP--FPIIPIFSDVPT-----ERMVPMNNNTKGCNESADD 235
Query: 234 XXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXX 293
+ L V + L+ Y+ + + FG +
Sbjct: 236 VSGPCSCQDCSLVCGPKPQPPPLPVLWTIFGLDAMYVIMWLS--YMGFLVIFFGLVLATW 293
Query: 294 XXXXXXXGSSAEPLLVSEGRSF-TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYG 352
S P+ + S T G D + ++ L + +G
Sbjct: 294 CHRKRNLVSEYAPIDSNLAYSVNTGYEDQGRSSCCDELGER------LERCLRTLFSTWG 347
Query: 353 RWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFY 412
+ P VL +L V + C GL + T P +LW P S+A +EKE+FDSH PF+
Sbjct: 348 CLCVQNPLPVLLCTLVFVTIGCCGLSYMKITTDPVELWSAPASQAHKEKEYFDSHFGPFF 407
Query: 413 RIEQLIIATLPESEHGKPPSIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVS 462
R EQLII S+ P D + E+LF++ Q ++ + A Y+ V
Sbjct: 408 RTEQLIITAPHASKTTYSPYPSGSDVPFGPPLDKEILFQVLDLQTAIENLVATYNNESVM 467
Query: 463 LSDICLKPLG---EDCATQSILQYFQMD--------PDNFDNYGGVE-HAEYCFQHYTST 510
L DICL PL +C S+L Y+Q D+F Y H YC + S
Sbjct: 468 LKDICLAPLAPYNNNCTILSVLNYYQNSYAVLNHSIGDDFFVYADYHTHFLYCVRAPASL 527
Query: 511 -------ETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
+ C F P+ P LGG+ +NY+ A+A +IT+PV N N KA+A
Sbjct: 528 NDTSMLHDPCLGTFGGPIFPWLVLGGYDSDNYNNATALVITFPVVNYHNDTKKVN-KALA 586
Query: 564 WEKAFIQLAK 573
WEK FI+ K
Sbjct: 587 WEKQFIEFVK 596
>H3BC00_LATCH (tr|H3BC00) Uncharacterized protein OS=Latimeria chalumnae PE=4
SV=1
Length = 1284
Score = 189 bits (481), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 168/591 (28%), Positives = 247/591 (41%), Gaps = 75/591 (12%)
Query: 40 EYCAMYDICGQRSDG--KVLNCPYP-SPSVKPHDLLSAKIQSLCPTI-TGNV--CCTEEQ 93
E C Y C + DG K NC Y +P PH+ +Q LCP GNV CC +Q
Sbjct: 29 ERCIWYGEC-ETVDGTEKRYNCNYTGAPVPLPHEGYDL-VQELCPGFFYGNVSLCCDIQQ 86
Query: 94 LQAVPI--------LVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV------DGNM 139
L+ + + L CP+C N +NLFCEL+CSP+QS F+N T +
Sbjct: 87 LKTLKVNLQLPLQFLSRCPSCFYNLMNLFCELTCSPHQSQFVNATKFKTYFDPVAKENKT 146
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFL----GQ 192
V + Y+ + F + +Y+ACKDV+ + N +A+ + G A N W ++
Sbjct: 147 DVIEVKYYIGQRFADAMYNACKDVEAPSSNEKALGLLCGKDAKDCNATNWIQYMFNTDNS 206
Query: 193 KVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
+ P FP P D T M MN + CN+++
Sbjct: 207 QTP--FPIIPIFSDVPT-----ERMVPMNNNTKGCNESADDVSGPCSCQDCSLVCGPKPQ 259
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
+ L V + L+ Y+ + + FG + S P+ +
Sbjct: 260 PPPLPVLWTIFGLDAMYVIMWLS--YMGFLVIFFGLVLATWCHRKRNLVSEYAPIDSNLA 317
Query: 313 RSF-TNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVI 371
S T G D + ++ L + +G + P VL +L V
Sbjct: 318 YSVNTGYEDQGRSSCCDELGER------LERCLRTLFSTWGCLCVQNPLPVLLCTLVFVT 371
Query: 372 LLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
+ C GL + T P +LW P S+A +EKE+FDSH PF+R EQLII S+ P
Sbjct: 372 IGCCGLSYMKITTDPVELWSAPASQAHKEKEYFDSHFGPFFRTEQLIITAPHASKTTYSP 431
Query: 432 SIVTDD-------NIELLFEI---QEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQ 478
D + E+LF++ Q ++ + A Y+ V L DICL PL +C
Sbjct: 432 YPSGSDVPFGPPLDKEILFQVLDLQTAIENLVATYNNESVMLKDICLAPLAPYNNNCTIL 491
Query: 479 SILQYFQMD--------PDNFDNYGGVE-HAEYCFQHYTST-------ETCFSAFKAPLE 522
S+L Y+Q D+F Y H YC + S + C F P+
Sbjct: 492 SVLNYYQNSYAVLNHSIGDDFFVYADYHTHFLYCVRAPASLNDTSMLHDPCLGTFGGPIF 551
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ +NY+ A+A +IT+PV N N KA+AWEK FI+ K
Sbjct: 552 PWLVLGGYDSDNYNNATALVITFPVVNYHNDTKKVN-KALAWEKQFIEFVK 601
>F7INK8_CALJA (tr|F7INK8) Uncharacterized protein (Fragment) OS=Callithrix
jacchus GN=NPC1 PE=4 SV=1
Length = 1254
Score = 189 bits (480), Expect = 3e-45, Method: Compositional matrix adjust.
Identities = 170/590 (28%), Positives = 243/590 (41%), Gaps = 78/590 (13%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVKP-----HDLLSAKIQSLCPTI---TGNVCCT 90
++ C Y CG K NC Y P KP +DL +Q LCP ++CC
Sbjct: 3 SQSCVWYGECGMAYGDKRYNCEYSGPP-KPLPKDGYDL----VQELCPGFFFDNVSLCCD 57
Query: 91 EEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT-- 140
+QLQ + L CP+C N LNLFCEL+CSP QS F+NVT+ +T
Sbjct: 58 VQQLQTLKDSLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQ 117
Query: 141 ----VDGIDLYVTETFGEGLYSACKDVKF-GTMNTRAIDFVGAGANNYKEWFAFLGQ--- 192
V + YV ++F +Y+AC+DV+ T I+ K FL
Sbjct: 118 TKTNVKELQYYVGQSFANAMYNACRDVEAPSTAKHNLIEL--------KPPILFLFSVVV 169
Query: 193 KVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
+ GF YS F ME MN + C D S+
Sbjct: 170 SISVGFSLDLYSTQFFPVDFPVHGMEPMNNATKGC-DESVDEATAPCSCQDCSIVCGPKP 228
Query: 253 XXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEG 312
M L + + + + + Y+ + + FG S P+ +
Sbjct: 229 QPPPPPAPWM-ILGLDAMYVIMWITYMAFLLMFFGAFFAVWCYRKRYFVSEYTPIDSNIA 287
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
S N GEV DP V +F + L + +G + R P V+ SL + +
Sbjct: 288 FS-VNASDKGEVSCCDP-----VSAAF-EGCLRQLFTRWGSFCVRNPGCVIFFSLVFIAV 340
Query: 373 LCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
GL+ V T P LW P S+A EKE+FD H PF+R EQLII +H P
Sbjct: 341 CSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIQAPLTDKHTYQPY 400
Query: 433 IVTDD-------NIELL---FEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQS 479
D +I++L ++Q ++ I A+Y+ V+L DICL PL +C S
Sbjct: 401 PSGADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCTIMS 460
Query: 480 ILQYFQMDPDNFDNYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEP 523
+L YFQ D+ G + H YC + S + C F P+ P
Sbjct: 461 VLNYFQNSHSVLDHKIGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFP 520
Query: 524 TTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
LGG+ NY+ A+A +IT+PV+N ++ +A AWEK FI K
Sbjct: 521 WLVLGGYDDQNYNNATALVITFPVSNYYNDT-EKLQRAQAWEKEFINFVK 569
>K0KA28_WICCF (tr|K0KA28) Niemann-Pick type C-related protein 1
OS=Wickerhamomyces ciferrii (strain F-60-10 / ATCC 14091
/ CBS 111 / JCM 3599 / NBRC 0793 / NRRL Y-1031) GN=NCR1
PE=4 SV=1
Length = 1213
Score = 187 bits (474), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 146/543 (26%), Positives = 242/543 (44%), Gaps = 61/543 (11%)
Query: 41 YCAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCP---TITGNVCCTEEQL-- 94
YC++YD CG++S G L CPY + + ++ LC +CCT Q+
Sbjct: 25 YCSIYDSCGKKSLFGSELPCPYNDKAFDAEEDQINELVGLCGEEWKQETKLCCTSGQISE 84
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI-SQVDGNMTVDGIDLY 147
+A ++ CPAC +NF NLFC+ +CSP+QSLF+++T + D V ++
Sbjct: 85 LKEKLKKADSLISSCPACQKNFRNLFCQFTCSPDQSLFVDITKTGTSTDRREIVTELNFN 144
Query: 148 VTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDF 207
+ + GLY +CK+VKF N A+D +G GA NYKE+ FLG + P GSP+ ++F
Sbjct: 145 INDEMASGLYDSCKNVKFSATNGYAMDLIGGGAKNYKEFLKFLGDE-KPLLGGSPFQMNF 203
Query: 208 KTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKV 267
+ + DSS E +N VY CND + K+G L
Sbjct: 204 QYSN-DSSNQEYLNDQVYDCNDET------YKCSCSDCPDICPELEKLSHSTCKVGILP- 255
Query: 268 RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVI 327
C S+ ++Y V + + I P L S + T+LP+ I
Sbjct: 256 -CFSFSVIIIYAVFLGIYIA-IHTYKVRGKRIQLLQESPYLRS---TTTDLPE------I 304
Query: 328 DPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF-NVETRP 386
+ + + +F + W S AY + ++ P VL +L + + L + F ++E P
Sbjct: 305 NTKNEVYSLNTFFETWFSKL--AY--YCSKYPATVLILTLLVTVPLSLCVYFFGDLEQNP 360
Query: 387 EKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNIELLFEIQ 446
LWV ++A ++KE+FD + PFYR EQ+ I E ++ D ++ + +
Sbjct: 361 VNLWVSSGAEAFKQKEYFDQNFGPFYRTEQIYIVNEDE-------GVLDDKTVKWWAKTE 413
Query: 447 EKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQMDPDNFDNYGGVEHAEYCFQ 505
++ I + + D+C KP + C +S QY FD+ + +
Sbjct: 414 LEIRSIIVDD----IMFEDLCFKPTEDSTCVVESFTQY-------FDDQIPRDWKKKLQD 462
Query: 506 HYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWE 565
TS C F+ PL+ GG+ ++ + A ++T +NN + + A WE
Sbjct: 463 CTTSPVNCLPTFQQPLKKELLFGGYENDDILTSKAIVVTLLLNN----IDEIQENATKWE 518
Query: 566 KAF 568
+
Sbjct: 519 NSL 521
>Q9GLC9_BOVIN (tr|Q9GLC9) Niemann-Pick type C1 disease protein OS=Bos taurus
GN=NPC1 PE=2 SV=1
Length = 1277
Score = 187 bits (474), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 164/591 (27%), Positives = 243/591 (41%), Gaps = 76/591 (12%)
Query: 39 NEYCAMYDICGQRSDGKVLNCPYPSPSVK-PHDLLSAKIQSLCPTIT-GNV--CCTEEQL 94
++ C Y CG S K NC Y P P D +Q LCP GNV CC +QL
Sbjct: 22 SQSCIWYGECGIASGDKRYNCRYSGPPEPLPQDGYDL-VQELCPGFFFGNVSLCCDVQQL 80
Query: 95 QAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VD-----GNMT 140
+ L CP+C N +NLFCEL+CSP QS F+NVT+ VD
Sbjct: 81 HTLKDNLQLPLQFLSRCPSCFYNLVNLFCELTCSPRQSQFLNVTATEDYVDPATNQTKTN 140
Query: 141 VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPPG 197
V + YV E+F +Y++C+DV+ + N +A+ + A A N W ++ K
Sbjct: 141 VKELQYYVGESFANAMYNSCRDVEAPSSNEKALGLLCGREASACNATNWIEYMFNK---D 197
Query: 198 FPGSPYSIDFKTTILDSSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXX 254
+P++I + L + ME MN + C+ D G
Sbjct: 198 NGQAPFTITPVFSDLPTHGMEPMNNATKGCDESVDEVTGPCSCQDCSAVCGPKPQPPPPP 257
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
+ + ++ V + Y+ + V FG S P+ + S
Sbjct: 258 VPWKILGLDAMYV-----IMWSTYMAFLLVFFGAFFAVWCYRKRYFVSEFTPIDGNIPFS 312
Query: 315 FTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLC 374
K G E + EW +G + R P V+ S+A +
Sbjct: 313 INASDKGGPTCCDPLGAAFEAHLRRLFEW-------WGSFCVRHPGCVVFFSVAFIAACS 365
Query: 375 FGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEH------- 427
GL+ V T P LW P S+A EKE+FD+H PF+R EQLII H
Sbjct: 366 SGLVFIQVTTDPVDLWSAPGSQARLEKEYFDTHFGPFFRTEQLIIRAPHTPPHIYEPYPS 425
Query: 428 ------GKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQ 478
G P ++ + + + ++Q ++ I A+Y+ V+L DIC+ PL ++C
Sbjct: 426 GADVPFGPPLAV---NILHQVLDLQTAIESITASYNNETVTLRDICVAPLSPYNQNCTIL 482
Query: 479 SILQYFQMDPDNFDNYGGVEHAEYCFQHY--------------TS--TETCFSAFKAPLE 522
S+L YFQ D+ G + Y H TS + C F P+
Sbjct: 483 SVLNYFQNSHSVLDHQVGDDFFVYADYHTHFLYWVRAPASLNDTSLLHDPCLGTFGGPVF 542
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P LGG+ NY+ A+A +IT+PVNN ++ +A AWEK FI +
Sbjct: 543 PWLVLGGYDDQNYNNATALVITFPVNNYYNDT-EKLQRAQAWEKEFINFVQ 592
>Q6CIF2_KLULA (tr|Q6CIF2) KLLA0F27137p OS=Kluyveromyces lactis (strain ATCC 8585
/ CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
GN=KLLA0F27137g PE=4 SV=1
Length = 1177
Score = 184 bits (468), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 153/549 (27%), Positives = 243/549 (44%), Gaps = 66/549 (12%)
Query: 27 LTAAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITG 85
+ A + + ++ E CAMY CG++ G L CP + +P + +Q L I G
Sbjct: 8 VAVALLIHTCYAQESCAMYGNCGKKGVFGASLPCPVDA-DFEPPVIDQGDVQFLV-DICG 65
Query: 86 -------NVCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVT 130
+CCT EQ++A+ I+ CPAC +NF +FC +CSPNQ FI++
Sbjct: 66 EEWRDNERLCCTREQMEALKENLNKAESIIASCPACKKNFNTIFCHFTCSPNQRQFIDII 125
Query: 131 SISQV-DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAF 189
S + DG V ++ ++ ++ Y +CK+VKF N A+D +G GA++Y E+ F
Sbjct: 126 STDESSDGREIVSELNFFLNSSWASSFYDSCKNVKFSATNGYAMDLIGGGASDYSEFMKF 185
Query: 190 LGQKVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
LG K P GSP+ I+++ S L + +V++C+D
Sbjct: 186 LGDK-KPALGGSPFQINYEYET-SSDEYSLFDENVFACSDPK-----------YKCACAD 232
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGW---IXXXXXXXXXXXGSS 303
IK G V C +L VLY + + GW I
Sbjct: 233 CSNSCPTLAPIKKGRCMVAGIPCTSFALLVLYALAFLAIGGWHIIIFRRRKIKSTNIVEG 292
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVL 363
+EPLL G + + DG L ++ + I + LSN A + P VL
Sbjct: 293 SEPLL-DNGNAANSDIDDG--LFVEYATERNAMNDKISDVLSNTVAA----CIKNPITVL 345
Query: 364 CSSLAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATL 422
S + +L L+ F ++ET P LWV P S +EK FD++ PFYR EQ+ I
Sbjct: 346 SYSAIFITILLIALIVFGDLETDPVNLWVNPSSPKFKEKTHFDANFGPFYRTEQVFIV-- 403
Query: 423 PESEHGKPPSIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSIL 481
+++ +N++ FE + + E + +S D+C +P + C +S+
Sbjct: 404 -----NDTGPVLSYENLKWWFETENLITENLLSTEN--ISYQDLCFRPTEDSTCVIESVT 456
Query: 482 QYFQ-MDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASA 540
QYFQ + P D + E C S C +F+ PL+ FS N E++A
Sbjct: 457 QYFQGILP---DESSWKQQLESCTD---SPVNCLPSFQQPLKTNVL---FSDENVFESNA 507
Query: 541 FIITYPVNN 549
F++T ++N
Sbjct: 508 FVVTLLLSN 516
>R4XFW5_9ASCO (tr|R4XFW5) Putative Patched sphingolipid transporter OS=Taphrina
deformans PYCC 5710 GN=TAPDE_002275 PE=4 SV=1
Length = 1254
Score = 182 bits (461), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 161/553 (29%), Positives = 246/553 (44%), Gaps = 50/553 (9%)
Query: 37 HSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLC--PTITGNVCCTEEQ 93
H C M CG+ S G L CPY ++ P +L + +C G +CC +Q
Sbjct: 6 HEQGRCMMRGQCGKESFFGAELPCPYNGKAIAPDQILRETVIDVCGDKYAEGPLCCDVDQ 65
Query: 94 LQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINV--TSISQVDGNMTVDG 143
L+A+ ++ CPAC NF FC +CSPNQS F+++ T+IS+ G +
Sbjct: 66 LEALRSNLKKAENLIASCPACKANFFEFFCTFTCSPNQSQFLDIEDTAISRT-GKEIITQ 124
Query: 144 IDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPY 203
+ YV G Y++CK+VKF N +D +G GA + F+GQK P G SP
Sbjct: 125 LAHYVDTDASTGFYNSCKNVKFSATNGYVMDLIGGGAQTAPAFLKFMGQKSPLG---SPI 181
Query: 204 SIDFKTTILDSSPMELMNA--SVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIK 261
ID+ +S+P ++ A + C+D
Sbjct: 182 QIDYP----ESTPASMVPAVLQAHECDDEDASFRCACVDCPTACPTLSGPDH-------P 230
Query: 262 MGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS-EGRSFTNLPK 320
+G V + V+ IV L I EP V + R +T+L
Sbjct: 231 VGRCHVGHLPCFSFVILIVYCLSLLSMIAFYLYKVRHSTQLRREPSRVHLDSREYTSLAD 290
Query: 321 DGEVLVIDPQR----QNEV-QYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCF 375
D E D Q+E+ + S + + L + G A+ P + S V LL
Sbjct: 291 DEEQDDGDDDGLLEPQDELAKTSPVNDALQKIFYKLGFVCAQYPYATIGVSFFFVSLLSV 350
Query: 376 GLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVT 435
G RF VET P +LWV PES AA+EK FFD+ PFYR +QL + + + S++T
Sbjct: 351 GWSRFAVETNPIRLWVSPESPAAQEKTFFDTTFGPFYRTQQLFLV----NGTSQNASVLT 406
Query: 436 DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGEDCATQSILQYFQMDPDNFDNYG 495
DN++ F +++ + ++A SG++ L DIC KP G+ C QS+ Y+Q + +
Sbjct: 407 YDNLKWWFNVEQDIYNLQA--SGVM--LEDICYKPTGDACVVQSVTGYWQGNQVELEQET 462
Query: 496 GVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVG 555
+ C + TC F+ PL+P T LGG+ G ++ A + + V N+L
Sbjct: 463 WEDVLLSCAEQPV---TCLPPFQQPLKPNTILGGYEGGVL-QSKALVSSIVVANSLEP-- 516
Query: 556 DENGKAIAWEKAF 568
+A+AWE+
Sbjct: 517 RIIARAMAWEQTL 529
>C5DXD6_ZYGRC (tr|C5DXD6) ZYRO0F04180p OS=Zygosaccharomyces rouxii (strain ATCC
2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)
GN=ZYRO0F04180g PE=4 SV=1
Length = 1180
Score = 181 bits (460), Expect = 5e-43, Method: Compositional matrix adjust.
Identities = 158/557 (28%), Positives = 244/557 (43%), Gaps = 83/557 (14%)
Query: 38 SNEYCAMYDICGQRS-DGKVLNCPY-----PSPSVKPHDLLSAKIQSLCPTITGNV---C 88
S CA+Y CG++S G L CP P P+ D L + S+C ++ C
Sbjct: 25 STAQCAIYGNCGKKSLFGTELPCPVQQDFQPEPA---SDELKELVVSVCGEEWQDIDTLC 81
Query: 89 CTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNM 139
CT++Q+ +A I+ CPAC +NF NLFC +CSP Q FINVT + +D
Sbjct: 82 CTKDQVVNLRNNLKKAQNIIASCPACTKNFNNLFCHFTCSPEQRNFINVTKTQESMDHKE 141
Query: 140 TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFP 199
V +D +V T+ Y +CK+VKF N A+D +G GAN+Y+ + FLG + P
Sbjct: 142 VVSELDFFVNSTWASAFYDSCKEVKFSATNGYAMDLIGGGANDYQHFLKFLGDE-KPLIG 200
Query: 200 GSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXX 259
GSP+ I++ + P N +VY+C+D
Sbjct: 201 GSPFQINYLYN--SNYPFREFNDAVYACDDPQY-----------KCACADCDSSCPRLDP 247
Query: 260 IKMGSLKV---RCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFT 316
+K G+ KV C S+ ++Y LF I G + ++ E S
Sbjct: 248 LKKGTCKVGKLNCFSFSVLMVYA----ALFAAIGIFHIYLFKFKGRKSP--IIDEDHSAI 301
Query: 317 N---LPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILL 373
N +D + D + N I +S+ R+A P +L + IV +L
Sbjct: 302 NSRMTSRDRLFEMYDTKSYN------INSKISSALGGVSRYAVNNPYFILALTAGIVAVL 355
Query: 374 CFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPS 432
L F +ET P LWV +EK +FD FYR+EQ+ + +E G S
Sbjct: 356 GLSLYEFGELETDPINLWVNKNDPKYQEKLYFDEKFGEFYRVEQVFVV----NETG---S 408
Query: 433 IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQ--MDPD 489
+++ D ++ F++++ + E + G VS D+C +P E C +S QYFQ + P+
Sbjct: 409 VLSYDTMKWWFDVEKHITESIKSVDG--VSYQDLCFRPTDESTCVVESFTQYFQGELPPE 466
Query: 490 NFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN 549
G + + C S C F+ PL P L FS +N + AF++T V+
Sbjct: 467 ----IGWKDQLKACTD---SPVNCLPTFQQPL-PENLL--FSEDNVFASHAFVVTLLVD- 515
Query: 550 ALTKVGDENGKAIAWEK 566
D + A+ WE+
Sbjct: 516 ------DHSNAAVLWEE 526
>A7S0G1_NEMVE (tr|A7S0G1) Predicted protein (Fragment) OS=Nematostella vectensis
GN=v1g99833 PE=4 SV=1
Length = 1277
Score = 180 bits (456), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 151/591 (25%), Positives = 249/591 (42%), Gaps = 70/591 (11%)
Query: 42 CAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKI-QSLCPTIT--GNVCCTEEQLQAV- 97
C Y C + LNC Y P+ + +D + I ++LCP I G CC QL+A+
Sbjct: 1 CVWYGQCTKPGQTPALNCLYNEPAKELNDTKAMNILKNLCPKIAQGGKTCCDLRQLEALD 60
Query: 98 -------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD--GNMTVDGIDLYV 148
CPAC +N L+++CE +CSP+QSLF++ TS+ ++ I+ Y+
Sbjct: 61 SNLNTLRQFTSRCPACWQNMLDMYCESTCSPDQSLFMDPTSVVGFPPYTPYMINTINYYI 120
Query: 149 TETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+ L+ +CKDV F N + ++ + A + ++ ++G +P+ I
Sbjct: 121 APEHKDQLFKSCKDVIFPGNNEKILNLLCGQSAETCSPQKLLEYMGST---SNGQAPFDI 177
Query: 206 DFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSL 265
+ I + M MN + Y C+++ +
Sbjct: 178 HYPEIIRPN--MTWMNQTSYKCSESFINPLTNRTSAKCSCQDCQGSCPVLPPEPPTPKQK 235
Query: 266 KVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPL-----LVSEGRSFTNLPK 320
+ + L++L VL+ V G+ + + +V+ G +T
Sbjct: 236 TI----IGLSILSFVLLVVFIGFFILFMGISCYKIFNKPAYMRLPDNVVARGVVYTEERP 291
Query: 321 DGEVLVIDPQRQN---EVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGL 377
V+ ++ R+ EV +++ L + +G W + P V+ + V +L G+
Sbjct: 292 PSNVINVEIARKPGCFEVMGVAMEQKLRKIFSLWGLWCSNHPYTVIAGCIVFVGILAGGV 351
Query: 378 LRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT---LPESEHGKPP--- 431
+++ P KLW P+S+A +EK+ FDS +PFYR EQLII P++ G
Sbjct: 352 GYYSIIKDPVKLWSAPQSRARQEKDLFDSKFSPFYRTEQLIITVNQNYPQNHTGYKQYPD 411
Query: 432 -------SIVTDDNIELLFEIQEKVDEI----RANYSGLLVSLSDICLKPLG---EDCAT 477
I D + ++Q + ++ N ++L D+C KPL C
Sbjct: 412 DKFIPFGPIFHLDLLNQALDLQNYLTDMVVPHTENGKTTNITLEDVCFKPLAPLNTKCTI 471
Query: 478 QSILQYFQMDPDNFDNYGGV--------EHAEYCFQHYTSTET-------CFSAFKAPLE 522
QS+ QYFQ + + +H YC TS E C P+
Sbjct: 472 QSVFQYFQNSKELLNKCRTTDYFHDDFHDHILYCTSAPTSLEDFKWGGGPCLGENGVPVN 531
Query: 523 PTTALGGFSGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
P ALGGF G +Y+ ASA IIT+ V N + +N KA +WEKAFI K
Sbjct: 532 PNIALGGFEGTDYNNASALIITFVVENHRDE--KKNAKAESWEKAFIDHMK 580
>A5BZU0_VITVI (tr|A5BZU0) Putative uncharacterized protein OS=Vitis vinifera
GN=VITISV_014157 PE=4 SV=1
Length = 1007
Score = 179 bits (455), Expect = 2e-42, Method: Compositional matrix adjust.
Identities = 82/106 (77%), Positives = 90/106 (84%), Gaps = 8/106 (7%)
Query: 37 HSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNVCCTEEQL-- 94
HS EYCAMYDICG+RSDGKVLNCPY +P+VKP + LSAKIQSLCP I+GNVCCTE Q
Sbjct: 864 HSPEYCAMYDICGERSDGKVLNCPYGTPAVKPDEFLSAKIQSLCPMISGNVCCTEAQFDT 923
Query: 95 ------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ 134
QA+P LVGCPACLRNFLNLFCELSCSPNQSLFINVTSI++
Sbjct: 924 LRAQVQQAIPFLVGCPACLRNFLNLFCELSCSPNQSLFINVTSIAK 969
>F1KQH8_ASCSU (tr|F1KQH8) Niemann-Pick C1 protein OS=Ascaris suum PE=2 SV=1
Length = 1299
Score = 179 bits (454), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 161/610 (26%), Positives = 248/610 (40%), Gaps = 104/610 (17%)
Query: 34 RSIHSNEYCAMYDICGQRSDGKVLNCPY---PSPSVKPHDLLSAKIQSLCPTI--TGN-- 86
R + CAM +CGQR NCPY P P PHD ++ LCP + GN
Sbjct: 19 RGVADRRRCAMRGVCGQRGHMH-QNCPYNGPPKPLDDPHD--GDLLRQLCPHLYQDGNKE 75
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ---- 134
CC QL+ + +L CP+C NF+ L+C+ +CSP Q F+ +T++S
Sbjct: 76 FCCDGAQLEHLAAQMTLPRQLLSRCPSCFTNFVQLWCDFTCSPRQGDFLRITAVSDDQFL 135
Query: 135 -VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDF---VGAGANNYKEWFAFL 190
+ V ++ YV + + GL +CK V+ A+ V + +WF F+
Sbjct: 136 IENETQYVTEVEYYVRDDYANGLLESCKGVR-AVGADYALSLMCGVSVAECSISQWFNFM 194
Query: 191 GQKVPPGFPGSPYSIDF----------------KTTILDSSPMELMNASVYSCNDTSLGX 234
G G P++IDF T I+ S +S SC D +
Sbjct: 195 GTYNEN--IGVPFTIDFIVGQNRSSSGAPISPPSTHIVPCSQAPFPGSSACSCQDCA--- 249
Query: 235 XXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXX 294
I G ++ +D L + + + F +
Sbjct: 250 --------------ATCRPEAPFPIITQGKCRIASIDCMLILSLVSFGGLCFAVVFFAAV 295
Query: 295 XXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRW 354
G+ + +++ + D ++ I E S+I+ L YG+
Sbjct: 296 QYGLRRGNETD---LADFKPAAGTLDDADLGTI------ESLGSWIESQLEAMCAHYGQL 346
Query: 355 AARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRI 414
RRP V + + +L G+ T P +LW S+A EK FFDS+ PFYR
Sbjct: 347 CTRRPLTVFGFGMLVALLCSTGMFFVRFTTDPVELWSCRGSRARTEKNFFDSNFGPFYRT 406
Query: 415 EQLIIATLPES-----------EHGKPPSIVTDDNIELLFEIQEKVDEIRANYS-GLLVS 462
EQLI+ +S E G ++ +FE+Q V + A G ++
Sbjct: 407 EQLIVYPRDQSFFLHDNQSNVFEQGYYGPAFRKPFLKNVFELQNAVTGLTAEMGDGTQIT 466
Query: 463 LSDICLKPLGED---CATQSILQYFQ-----MDPDNFDNYGGVE-----HAEYCFQH-YT 508
L D+C KP+ D C SIL YFQ +D + D++ G E H C + YT
Sbjct: 467 LRDVCFKPMAPDNRNCTIMSILNYFQNDVRLLDEVSADDWTGAEFDYLDHILTCAHNPYT 526
Query: 509 STE----TCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
+C SAF PL+P LG F + N + A +IT ++N L G+E +A+A
Sbjct: 527 VASRLGVSCISAFGVPLQPYVILGDFNTTNQFDSARGVVITILLDNHLAHEGNE--RAVA 584
Query: 564 WEKAFIQLAK 573
WEK F++ +
Sbjct: 585 WEKEFVRYLR 594
>F1KQ97_ASCSU (tr|F1KQ97) Niemann-Pick C1 protein OS=Ascaris suum PE=2 SV=1
Length = 1303
Score = 179 bits (454), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 161/610 (26%), Positives = 248/610 (40%), Gaps = 104/610 (17%)
Query: 34 RSIHSNEYCAMYDICGQRSDGKVLNCPY---PSPSVKPHDLLSAKIQSLCPTI--TGN-- 86
R + CAM +CGQR NCPY P P PHD ++ LCP + GN
Sbjct: 19 RGVADRRRCAMRGVCGQRGHMH-QNCPYNGPPKPLDDPHD--GDLLRQLCPHLYQDGNKE 75
Query: 87 VCCTEEQLQAVP--------ILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ---- 134
CC QL+ + +L CP+C NF+ L+C+ +CSP Q F+ +T++S
Sbjct: 76 FCCDGAQLEHLAAQMTLPRQLLSRCPSCFTNFVQLWCDFTCSPRQGDFLRITAVSDDQFL 135
Query: 135 -VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDF---VGAGANNYKEWFAFL 190
+ V ++ YV + + GL +CK V+ A+ V + +WF F+
Sbjct: 136 IENETQYVTEVEYYVRDDYANGLLESCKGVR-AVGADYALSLMCGVSVAECSISQWFNFM 194
Query: 191 GQKVPPGFPGSPYSIDF----------------KTTILDSSPMELMNASVYSCNDTSLGX 234
G G P++IDF T I+ S +S SC D +
Sbjct: 195 GTYNEN--IGVPFTIDFIVGQNRSSSGAPISPPSTHIVPCSQAPFPGSSACSCQDCA--- 249
Query: 235 XXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXX 294
I G ++ +D L + + + F +
Sbjct: 250 --------------ATCRPEAPFPIITQGKCRIASIDCMLILSLVSFGGLCFAVVFFAAV 295
Query: 295 XXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRW 354
G+ + +++ + D ++ I E S+I+ L YG+
Sbjct: 296 QYGLRRGNETD---LADFKPAAGTLDDADLGTI------ESLGSWIESQLEAMCAHYGQL 346
Query: 355 AARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRI 414
RRP V + + +L G+ T P +LW S+A EK FFDS+ PFYR
Sbjct: 347 CTRRPLTVFGFGMLVALLCSTGMFFVRFTTDPVELWSCRGSRARTEKNFFDSNFGPFYRT 406
Query: 415 EQLIIATLPES-----------EHGKPPSIVTDDNIELLFEIQEKVDEIRANYS-GLLVS 462
EQLI+ +S E G ++ +FE+Q V + A G ++
Sbjct: 407 EQLIVYPRDQSFFLHDNQSNVFEQGYYGPAFRKPFLKNVFELQNAVTGLTAEMGDGTQIT 466
Query: 463 LSDICLKPLGED---CATQSILQYFQ-----MDPDNFDNYGGVE-----HAEYCFQH-YT 508
L D+C KP+ D C SIL YFQ +D + D++ G E H C + YT
Sbjct: 467 LRDVCFKPMAPDNRNCTIMSILNYFQNDVRLLDEVSADDWTGAEFDYLDHILTCAHNPYT 526
Query: 509 STE----TCFSAFKAPLEPTTALGGF-SGNNYSEASAFIITYPVNNALTKVGDENGKAIA 563
+C SAF PL+P LG F + N + A +IT ++N L G+E +A+A
Sbjct: 527 VASRLGVSCISAFGVPLQPYVILGDFNTTNQFDSARGVVITILLDNHLAHEGNE--RAVA 584
Query: 564 WEKAFIQLAK 573
WEK F++ +
Sbjct: 585 WEKEFVRYLR 594
>B4HWH4_DROSE (tr|B4HWH4) GM11941 OS=Drosophila sechellia GN=Dsec\GM11941 PE=4
SV=1
Length = 1287
Score = 179 bits (453), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 148/592 (25%), Positives = 243/592 (41%), Gaps = 90/592 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPH----DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C + NCPY + + +LL + L CC + Q
Sbjct: 29 SKQDCVWYGVCNTNENSHSQNCPYNGTAKEMAADGLELLKKRCGFLLENSENKFCCDKNQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A IL CP+C+ N + C+ +CSP Q+ F++V + + G+ + +
Sbjct: 89 VELLNKNVELAGNILDRCPSCMENLMRHICQFTCSPKQAEFMHVVATQKNKKGDEYISSV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+++ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P +N + CN
Sbjct: 208 ------FQITYIQHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ L VLVF++ GS L ++G S
Sbjct: 262 PRPEPFKIVGLDAYFVIMASVFLVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVID-PQRQNEVQY----SFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
N P DG + + P +N+ + + + +L F+ +G + A P + L + +
Sbjct: 303 MDDNFPVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGAS 362
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII--ATLPESE 426
+V++L +G+ + T P KLW P SK+ E+EFFD+ +PFYR+EQ+II LP+
Sbjct: 363 LVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIV 422
Query: 427 HGKPPS------IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------ 474
H + D + + ++QE + EI AN + L DIC PL D
Sbjct: 423 HNTSNGPYTFGPVFDRDFLSKVLDLQEGIKEINANGT----QLKDICYAPLSYDGSKIDV 478
Query: 475 --CATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTAL 527
C QSI YF ++D + DN V + + + ++ C + + P++P AL
Sbjct: 479 SKCVVQSIWGYFGDDRERLDYHDDDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIAL 538
Query: 528 GGF--------SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GGF + A+A I+T+ V N K EN A+ WEK F++
Sbjct: 539 GGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKTDLEN--ALTWEKKFVEF 588
>F7INM5_CALJA (tr|F7INM5) Uncharacterized protein OS=Callithrix jacchus GN=NPC1
PE=4 SV=1
Length = 1189
Score = 179 bits (453), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 145/506 (28%), Positives = 216/506 (42%), Gaps = 47/506 (9%)
Query: 103 CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT------VDGIDLYVTETFGEGL 156
CP+C N LNLFCEL+CSP QS F+NVT+ +T V + YV ++F +
Sbjct: 11 CPSCFYNLLNLFCELTCSPRQSQFLNVTATEDYVDPVTNQTKTNVKELQYYVGQSFANAM 70
Query: 157 YSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP 216
Y+AC+DV+ + N +A+ + + W+ + G G+ YS F
Sbjct: 71 YNACRDVEAPSSNDKALGLL-VSPSKRGNWYIY-PVLAKLGGAGNLYSTQFFPVDFPVHG 128
Query: 217 MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAV 276
ME MN + C D S+ M L + + + + +
Sbjct: 129 MEPMNNATKGC-DESVDEATAPCSCQDCSIVCGPKPQPPPPPAPWM-ILGLDAMYVIMWI 186
Query: 277 LYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQ 336
Y+ + + FG S P+ + S N GEV DP V
Sbjct: 187 TYMAFLLMFFGAFFAVWCYRKRYFVSEYTPIDSNIAFS-VNASDKGEVSCCDP-----VS 240
Query: 337 YSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESK 396
+F + L + +G + R P V+ SL + + GL+ V T P LW P S+
Sbjct: 241 AAF-EGCLRQLFTRWGSFCVRNPGCVIFFSLVFIAVCSSGLVFVRVTTNPVDLWSAPSSQ 299
Query: 397 AAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD-------NIELLFEI---Q 446
A EKE+FD H PF+R EQLII +H P D +I++L ++ Q
Sbjct: 300 ARLEKEYFDQHFGPFFRTEQLIIQAPLTDKHTYQPYPSGADVPFGPPLDIQILHQVLDLQ 359
Query: 447 EKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSILQYFQMDPDNFDNYGGVE----- 498
++ I A+Y+ V+L DICL PL +C S+L YFQ D+ G +
Sbjct: 360 IAIENITASYNNETVTLQDICLAPLSPYNTNCTIMSVLNYFQNSHSVLDHKIGDDFFVYA 419
Query: 499 ----HAEYCFQHYTST-------ETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPV 547
H YC + S + C F P+ P LGG+ NY+ A+A +IT+PV
Sbjct: 420 DYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPV 479
Query: 548 NNALTKVGDENGKAIAWEKAFIQLAK 573
+N ++ +A AWEK FI K
Sbjct: 480 SNYYNDT-EKLQRAQAWEKEFINFVK 504
>B3MPM8_DROAN (tr|B3MPM8) GF14130 OS=Drosophila ananassae GN=Dana\GF14130 PE=4
SV=1
Length = 1286
Score = 178 bits (452), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 153/591 (25%), Positives = 245/591 (41%), Gaps = 89/591 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVK-PH---DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C + NCPY +++ P DLL + L CC EQ
Sbjct: 29 SKQDCVWYGVCNTNAFQHSQNCPYNGTAIEMPQAGLDLLKERCGFLLQNNENKYCCDTEQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A L CP+C+ N + CE +CSP QS F++V + + G + +
Sbjct: 89 VKILNKNVKLAGNFLDRCPSCMENLVRHICEFTCSPKQSEFMHVAATEKNKTGGSYISAV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+V+ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHVSTDYINKTYKSCSQVSVPQTGQLAFDLMCGSYPASRCNPTKWFNFMGDATSPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P + + CN
Sbjct: 208 ------FQITYIQHEPKSNSKEFKPLGPPTIPCNQAVSSELPACSCSDCEKSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ VLVF++ GS L ++G S
Sbjct: 262 PPPEPFKIFGLDAYLVIMAAVFFVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVIDPQRQNEVQYSFI----QEWLSNFYRAYGRWAARRPTIVLCSSLAI 369
N DG + D +++ + + + +L F+ +G + A P + L + +
Sbjct: 303 LDENFQIDGNDVTDDMAYRDDSYFEKLGARTETFLEQFFTKWGTFFASNPWMTLVAGACL 362
Query: 370 VILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT--LPESEH 427
V++L +G+ N+ T P KLW P SK+ E+EFFD+ PFYR+EQ+II LP+ H
Sbjct: 363 VVVLGYGVSHINITTDPVKLWASPNSKSRLEREFFDTKFEPFYRLEQIIIKAVDLPQIVH 422
Query: 428 GKPPSIVT------DDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------- 474
+T + + + +QE + ++ AN + +L DIC PL ED
Sbjct: 423 NTSNGPITFGPVFDREFLTNVLYLQEGIKKLNANGT----TLKDICFAPLSEDGNALEDS 478
Query: 475 -CATQSILQYFQMDPDNFDNY---GG--VEHAEYCFQHYTSTETCFSAFKAPLEPTTALG 528
C QSI YFQ D + D+ GG V + + FQ ++ C + + P++P ALG
Sbjct: 479 NCVVQSIWGYFQDDIERLDDEEEDGGFNVTYLDALFQCTSNPYLCLAPYGGPVDPAIALG 538
Query: 529 GF-------SGN-NYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GF +GN Y A+A I+T+ V N + + +A+ WEK F++
Sbjct: 539 GFLRAGDQLTGNTKYELANALILTFLVKNHHNRT--DLHRALEWEKMFVEF 587
>C7GV50_YEAS2 (tr|C7GV50) Ncr1p OS=Saccharomyces cerevisiae (strain JAY291)
GN=NCR1 PE=4 SV=1
Length = 1170
Score = 178 bits (451), Expect = 6e-42, Method: Compositional matrix adjust.
Identities = 140/548 (25%), Positives = 247/548 (45%), Gaps = 71/548 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGW--IXXXXXXXXXXXGSSA 304
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMWYYLFKRKENGAMIVDDDI 294
Query: 305 EPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLC 364
P S S TN+ + NE +F L+N + G+++ P +L
Sbjct: 295 VPESASLDESETNVFE---------SFNNET--NFFNGKLANLFSRVGQFSVENPYKILI 343
Query: 365 SSLAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLP 423
+++ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ +
Sbjct: 344 TTVFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV--- 400
Query: 424 ESEHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSIL 481
+E G +++ + + F+++ + +E++++ + + D+C +P + C +S
Sbjct: 401 -NETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFT 453
Query: 482 QYFQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
QYFQ N D++ + C + + C F+ PL+ FS ++ A AF
Sbjct: 454 QYFQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAF 505
Query: 542 IITYPVNN 549
++T + N
Sbjct: 506 VVTLLLTN 513
>H3ITD6_STRPU (tr|H3ITD6) Uncharacterized protein OS=Strongylocentrotus purpuratus
PE=4 SV=1
Length = 2794
Score = 178 bits (451), Expect = 7e-42, Method: Compositional matrix adjust.
Identities = 172/613 (28%), Positives = 258/613 (42%), Gaps = 122/613 (19%)
Query: 36 IHSNEYCAMYDICGQRSDGKV---LNC-----PYPSPSVKPHDLLSAKIQSLCPTITGN- 86
+H C MY CG D + LNC P+ S + LL+ CP
Sbjct: 1474 LHEEGRCMMYSECGANPDTNLRTYLNCLDNEVARPTESAAANGLLN----DFCPAYNPEE 1529
Query: 87 VCCTEEQLQAV-PILVG-------CPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGN 138
VCC +QL+ + P+L CPACL N L + C++ CSP QSL+ N T + D
Sbjct: 1530 VCCDLQQLRTMQPLLTALRPAFGRCPACLENILTMMCQMVCSPQQSLYTNATVLLVSDDG 1589
Query: 139 MTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAG----ANNYKEWFAFLGQKV 194
+ V D +V + F + Y +CKDV+F NT +D + G + + W FLG
Sbjct: 1590 VGVRRFDAFVAQEFADVAYDSCKDVQFPAANTPVMDVMCGGYLGDDCSPQRWLDFLGDTA 1649
Query: 195 PPGFPGSPYSIDFKTTI-------LDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXX 247
GF P++IDFK +D S ME MN + + C + +G
Sbjct: 1650 N-GF--IPWNIDFKIVPTGETVEGMDES-MEPMNPTSFYC-NAPVGNQSSCSCQDCELSC 1704
Query: 248 XXXXXXXXXXXXIKMG-----SLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGS 302
K+G S + + + LA L++V +L+
Sbjct: 1705 SALPTIGPVVPPYKIGLMDGYSFIILMIYVGLACLFVV-SLILYNC-------------- 1749
Query: 303 SAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQY------------SFIQEWLSNFYRA 350
L+VS D E L P R+NEV+ + + L +F+
Sbjct: 1750 ----LVVS---------NDDEEL---PLRKNEVRIEPEDVGKLDNFNKKMDDGLRDFFTW 1793
Query: 351 YGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAP 410
+G AR P +VL + +V+ L G+L + T P +LW GP+S+A EK+++D P
Sbjct: 1794 WGTGIARYPVLVLFIMVCVVVALTCGILLVEIVTDPVELWSGPQSRARLEKDYYDETFVP 1853
Query: 411 FYRIEQLIIA----------TLPESEHGKPPSIVTDDNIELL---FEIQEKVDEIRANYS 457
FYR + I T E P + N+E+L ++Q+ V+ I A Y
Sbjct: 1854 FYRTTLIYIRAPGMDYVEYDTYNEGNKTFGPVV----NLEVLTQALDLQKAVENITAYYK 1909
Query: 458 GLLVSLSDICLKPLG---EDCATQSILQYF-----QMDPDNFDNYGGV----EHAEYCFQ 505
G V LSDIC KPL C QS+LQ++ Q++ D G +H YC +
Sbjct: 1910 GSPVRLSDICNKPLAPVVNQCLIQSVLQWYGNSYEQLNKVAVDGEGKSADYRDHFIYCMK 1969
Query: 506 HYTSTE-------TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN 558
S E C SAF P P A+GG+ ++Y+EA IT ++N + N
Sbjct: 1970 SPLSLEDNTPLRDMCVSAFGGPTYPYVAIGGYPDDDYNEAELLAITILLDNKKENETEYN 2029
Query: 559 GKAIAWEKAFIQL 571
+ WE +++
Sbjct: 2030 -MILEWEAEYLRF 2041
>G2WPH4_YEASK (tr|G2WPH4) K7_Ncr1p OS=Saccharomyces cerevisiae (strain Kyokai no.
7 / NBRC 101557) GN=K7_NCR1 PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLFKRKENGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFSRVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>H0GPT2_9SACH (tr|H0GPT2) Ncr1p OS=Saccharomyces cerevisiae x Saccharomyces
kudriavzevii VIN7 GN=VIN7_5022 PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKDWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLCKRKKNGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFTKVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>A6ZWP0_YEAS7 (tr|A6ZWP0) Niemann-Pick type C-related protein OS=Saccharomyces
cerevisiae (strain YJM789) GN=NCR1 PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLFKRKENGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFSRVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>C8ZJ20_YEAS8 (tr|C8ZJ20) Ncr1p OS=Saccharomyces cerevisiae (strain Lalvin EC1118
/ Prise de mousse) GN=EC1118_1P2_3048g PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLCKRKKNGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFTKVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>N1NVZ9_YEASX (tr|N1NVZ9) Ncr1p OS=Saccharomyces cerevisiae CEN.PK113-7D
GN=CENPK1137D_1695 PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLCKRKKNGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFTKVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>B3LL56_YEAS1 (tr|B3LL56) Transmembrane protein OS=Saccharomyces cerevisiae
(strain RM11-1a) GN=SCRG_02484 PE=4 SV=1
Length = 1170
Score = 177 bits (449), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 140/546 (25%), Positives = 248/546 (45%), Gaps = 67/546 (12%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN- 86
Q+ R + CAMY CG++S G L CP P P +LS + L + G
Sbjct: 10 VGQLMRLVQGTATCAMYGNCGKKSVFGNELPCPVPRSFEPP--VLSDETSKLLVEVCGEE 67
Query: 87 ------VCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
CCT++Q+ +A P++ CPACL+NF NLFC +C+ +Q F+N+T +
Sbjct: 68 WKEVRYACCTKDQVVALRDNLQKAQPLISSCPACLKNFNNLFCHFTCAADQGRFVNITKV 127
Query: 133 --SQVDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFL 190
S+ D ++ + +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FL
Sbjct: 128 EKSKEDKDIVAE-LDVFMNSSWASEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFL 186
Query: 191 GQKVPPGFPGSPYSIDFKTTIL-DSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXX 249
G P GSP+ I++K + + + N VY+C+D
Sbjct: 187 GD-AKPMLGGSPFQINYKYDLANEEKEWQEFNDEVYACDDAQYK-----------CACSD 234
Query: 250 XXXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+K G KV C LS+ + Y + F W +
Sbjct: 235 CQESCPHLKPLKDGVCKVGPLPCFSLSVLIFYTICALFAFMW--YYLCKRKKNGAMIVDD 292
Query: 307 LLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSS 366
+V E S + E V + NE +F L+N + G+++ P +L ++
Sbjct: 293 DIVPESGSL----DESETNVFE-SFNNET--NFFNGKLANLFTKVGQFSVENPYKILITT 345
Query: 367 LAIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPES 425
+ + + F + ++ +ET P LWV S+ +EKE+FD + PFYR EQ+ + +
Sbjct: 346 VFSIFVFSFIIFQYATLETDPINLWVSKNSEKFKEKEYFDDNFGPFYRTEQIFVV----N 401
Query: 426 EHGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQY 483
E G +++ + + F+++ + +E++++ + + D+C +P + C +S QY
Sbjct: 402 ETG---PVLSYETLHWWFDVENFITEELQSSEN---IGYQDLCFRPTEDSTCVIESFTQY 455
Query: 484 FQMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFII 543
FQ N D++ + C + + C F+ PL+ FS ++ A AF++
Sbjct: 456 FQGALPNKDSWK--RELQECGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVV 507
Query: 544 TYPVNN 549
T + N
Sbjct: 508 TLLLTN 513
>H0XHF3_OTOGA (tr|H0XHF3) Uncharacterized protein OS=Otolemur garnettii GN=NPC1L1
PE=4 SV=1
Length = 1308
Score = 175 bits (444), Expect = 4e-41, Method: Compositional matrix adjust.
Identities = 162/613 (26%), Positives = 252/613 (41%), Gaps = 106/613 (17%)
Query: 30 AQISRSIHSNEYCAMYDICGQR---SDGKV----LNCPYPSPSVKPHDLLSAKIQSLCPT 82
+++ IH YCA YD CG+ S G ++C +P+ A ++S+CP
Sbjct: 21 SELYTPIHQPGYCAFYDECGKNPELSGGLTSLANVSCLSNTPARNITGEHLALLRSICPR 80
Query: 83 I-----TGNVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINV 129
+ T CC+ +QL ++ +L CPAC NF++L C +CS NQSLFINV
Sbjct: 81 LYTGPTTTQACCSVKQLVSLEASMSLTKALLTRCPACSDNFVSLHCHNTCSSNQSLFINV 140
Query: 130 TSISQ--VDGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNY 183
T ++Q V V + + +F E Y +C V+ + A+ + G+ N
Sbjct: 141 TRVAQRGVGQPPAVVAYEAFYQRSFAEQTYDSCSRVRIPAAASLAVGTMCGVYGSALCNA 200
Query: 184 KEWFAFLGQKVPPGFPGSPYSIDFKTTILDSSP---MELMNASVYSCNDTSLGXXXXXXX 240
+ W F G G +P I F +P M+ +N + CN++ G
Sbjct: 201 QRWLDFQGDT---GNGLAPLDITFHLRGPGETPGSGMQPLNEKIVHCNESQGGNTMACSC 257
Query: 241 XXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVL-VFVLFG-WIXXXXXXXXX 298
+G ++ LAV+ I+ VFVL ++
Sbjct: 258 QDCAASCPVIARPPALDFTFHLGQMQG-----GLAVIIIICSVFVLLTIFLVYFRVAPSK 312
Query: 299 XXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARR 358
G E EG SF N +++ S I L F++ +G W A
Sbjct: 313 DKGKKVE---TKEGASFPN----------------KLRLS-IHTLLGQFFQGWGTWVASW 352
Query: 359 PTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLI 418
P +L S +V+ L GL + T P +LW P S+A +EK F D H PF+R Q+I
Sbjct: 353 PLTILVFSTMLVVALASGLTYMELTTDPVELWSAPNSQARKEKAFHDQHFGPFFRTNQVI 412
Query: 419 IATLPESEHGKPPSIVTDDNIELLF----------------EIQEKVDEIRANYSGLLVS 462
+ S + ++ N + +Q E + N +S
Sbjct: 413 LTASNRSSYRYDSLLLGPKNFSGVLALDLLLELLELQERLRHLQVWSPEAQRN-----IS 467
Query: 463 LSDICLKPLG------EDCATQSILQYFQMDP------------------DNFDNYGGVE 498
L DIC PL DC S+LQYFQ + D D++
Sbjct: 468 LQDICYAPLNPHNASLSDCCINSLLQYFQNNRTLLQLTANQTLLGQTSQVDWRDHFLYCA 527
Query: 499 HAEYCFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDE 557
+A F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN +
Sbjct: 528 NAPLTFKDGTALALSCMADYGAPVFPFLAVGGYKGKDYSEAEALIMTFSLNNYPAE-DPR 586
Query: 558 NGKAIAWEKAFIQ 570
G+A WEKAF++
Sbjct: 587 LGQAKLWEKAFLE 599
>G8ZR59_TORDC (tr|G8ZR59) Uncharacterized protein OS=Torulaspora delbrueckii
(strain ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 /
NRRL Y-866) GN=TDEL0C01120 PE=4 SV=1
Length = 1173
Score = 175 bits (443), Expect = 5e-41, Method: Compositional matrix adjust.
Identities = 148/556 (26%), Positives = 239/556 (42%), Gaps = 86/556 (15%)
Query: 42 CAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITGN-------VCCTEEQ 93
CA+YD CG++S G L CP +P + + ++ L + G +CCT +Q
Sbjct: 24 CALYDNCGKKSVFGAELPCPVSDSRFRPPPV-TDELMDLVVEVCGEEWKDETELCCTLDQ 82
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNM-TVDGI 144
+Q A I+ CPAC++NF NLFC +CSP Q F+NVT I + V +
Sbjct: 83 VQNLQKNLKKAQNIIASCPACVKNFNNLFCHFTCSPEQVDFVNVTRIQKSTSKKDIVAEV 142
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYS 204
D+Y+ ++ Y +CKDVKF N A+D +G GA NY ++ FLG + P GSP+
Sbjct: 143 DVYMNSSWASVFYDSCKDVKFSATNGYAMDLIGGGAKNYSQFLKFLGDE-KPLLGGSPFQ 201
Query: 205 IDFKTTILDSSPME--LMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKM 262
I++ LD + + L + SVY CND +K
Sbjct: 202 INYLYE-LDGAKDDFILFDDSVYECNDPK-----------YKCACADCGLSCPELKPLKE 249
Query: 263 GSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXX-------GSSAEPLLVSEG 312
GS KV C ++ ++Y VL+ + W GS+ + S+
Sbjct: 250 GSCKVGKLPCFSFAVLMIYAVLIVAVVIWHIHLFRSKSRISLITSDEDGSAYNSQMTSDD 309
Query: 313 RSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVIL 372
R F N+V SF +++A P + + IV
Sbjct: 310 RLFDTYDTSSY------DFNNKVATSF---------ATLSKYSALNPYLTTALTAVIVAF 354
Query: 373 LCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPP 431
F L R+ ++E P LWV +S+ +EK +FD + PFYR+EQ+ + +E G
Sbjct: 355 FGFLLYRYGDLEREPINLWVSKDSQKYQEKRYFDENFGPFYRVEQVFVV----NETGP-- 408
Query: 432 SIVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQMDPDN 490
+++ D + E++ + + + + D+C +P E C +S +QYF P+
Sbjct: 409 -VLSYDTMRWWSEVEHNISQTIMSQDN--ATYQDLCFRPTAESTCVLESFIQYF---PNG 462
Query: 491 FDNYGG-VEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN 549
E + C S C +F+ PL+ FS + E++AF+ T+ ++N
Sbjct: 463 LPGQNTWREELQLCTD---SPVNCLPSFQQPLKKNLL---FSDDEVFESNAFVTTFLMSN 516
Query: 550 ALTKVGDENGKAIAWE 565
+ A+ WE
Sbjct: 517 -------HSSTAVDWE 525
>B7ZLE6_HUMAN (tr|B7ZLE6) NPC1L1 protein OS=Homo sapiens GN=NPC1L1 PE=2 SV=1
Length = 1286
Score = 174 bits (441), Expect = 8e-41, Method: Compositional matrix adjust.
Identities = 160/612 (26%), Positives = 252/612 (41%), Gaps = 115/612 (18%)
Query: 35 SIHSNEYCAMYDICGQRSD--GKVL-----NCPYPSPSVKPHDLLSAKIQSLCPTI-TG- 85
+IH YCA YD CG+ + G ++ +C +P+ K +Q +CP + TG
Sbjct: 26 TIHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGP 85
Query: 86 --NVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQV 135
CC+ +QL ++ +L CPAC NF+NL C +CSPNQSLFINVT ++Q+
Sbjct: 86 NTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQL 145
Query: 136 DGNM--TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAF 189
V + + +F E Y +C V+ T A+ + G+ N + W F
Sbjct: 146 GAGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNF 205
Query: 190 LGQKVPPGFPGSPYSIDFKTTILD-----SSPMELMNASVYSCNDTSLGXXXXXXXXXXX 244
G G +P I F +L+ S ++ +N V CN++
Sbjct: 206 QGDT---GNGLAPLDITFH--LLEPGQAVGSGIQPLNEGVARCNESQGDDVATCSCQDCA 260
Query: 245 XXXXXXXXXXXXXXXIKMGSLKVRCV-DLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSS 303
+G + V + L ++ V+ +L G
Sbjct: 261 ASCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVG---------------- 304
Query: 304 AEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEV--QYSF-IQEWLSNFYRAYGRWAARRPT 360
F P + ++DP++ + + SF L F++ +G W A P
Sbjct: 305 -----------FRVAPARDKSKMVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPL 353
Query: 361 IVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIA 420
+L S+ V+ L GL+ + T P +LW P S+A EK F D H PF+R Q+I+
Sbjct: 354 TILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILT 413
Query: 421 TLPESEHGKPPSIVTDDNI----------------ELLFEIQEKVDEIRANYSGLLVSLS 464
S + ++ N E L +Q E + N +SL
Sbjct: 414 APNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-----ISLQ 468
Query: 465 DICLKPLGE------DCATQSILQYFQMDP------------------DNFDNYGGVEHA 500
DIC PL DC S+LQYFQ + D D++ +A
Sbjct: 469 DICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANA 528
Query: 501 EYCFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN- 558
F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN GD
Sbjct: 529 PLTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNN--YPAGDPRL 586
Query: 559 GKAIAWEKAFIQ 570
+A WE+AF++
Sbjct: 587 AQAKLWEEAFLE 598
>C5DBG1_LACTC (tr|C5DBG1) KLTH0A02332p OS=Lachancea thermotolerans (strain ATCC
56472 / CBS 6340 / NRRL Y-8284) GN=KLTH0A02332g PE=4
SV=1
Length = 1179
Score = 174 bits (440), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 151/549 (27%), Positives = 248/549 (45%), Gaps = 76/549 (13%)
Query: 42 CAMYDICGQRS-DGKVLNCPYPSPSVKPHDLLSAKIQSLCPTI------TGNVCCTEEQL 94
C++Y CG++S G L CP V P L A+ +SL VCC Q+
Sbjct: 36 CSIYGSCGKKSLFGGELPCPVTEDFV-PDPLSEAERESLVDLCGEEWKDVNQVCCNGAQI 94
Query: 95 Q--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI-SQVDGNMTVDGID 145
+ A ++ CPAC +NF +LFC +CSP Q +F NVT S DG V ++
Sbjct: 95 ENLRKNLKKAENLIASCPACDKNFKSLFCHFTCSPQQRVFTNVTETQSSTDGREIVASMN 154
Query: 146 LYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLGQKVPPGFPGSPYSI 205
+++ + Y +CK+VKFG N A+D +G GA NY+++ FLG + P GSP+ I
Sbjct: 155 VFLDSHWASEFYDSCKNVKFGATNGYAMDLIGGGAKNYEQFLKFLGDE-KPLLGGSPFQI 213
Query: 206 DFKTTILDS--SPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMG 263
++ I DS S +EL N +VYSC+D + ++
Sbjct: 214 NY---IYDSQNSGIELFNETVYSCDDETY-----------KCACTDCDKSCPKLKPLRRN 259
Query: 264 SLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
KV C + ++Y+ L ++ GW + EP++ + +
Sbjct: 260 HCKVAGLPCFSFVILMVYVSLFVLILGW-------HIYYFKNRKEPIIFEQDIEDSYAVA 312
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV-LCSSLAIVILLCFGLLR 379
+ + + Q YSF ++ S + G ++ R P +V L + + +V+L +
Sbjct: 313 NNDRIF---QEHAYKAYSFDEKVASVLGQISG-FSYRHPKLVILATGVVVVLLTVLAWIF 368
Query: 380 FNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDNI 439
++ET P LWV S +EKEFFD + PFYR EQ+ I +E G +++ N+
Sbjct: 369 GDLETDPINLWVSKSSPKYKEKEFFDENFGPFYRTEQIFIV----NETGP---VLSYPNL 421
Query: 440 ELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQMD-PDNFDNYGGV 497
E F ++ + E+ S + D+C +P + C +S+ QYF D P D +
Sbjct: 422 EWWFGVESYITEVLR--SEEYQTYQDLCFRPTEDSTCVVESVTQYFNQDLPKEGDWENRL 479
Query: 498 EHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDE 557
+ S C +F+ PL+P FS N+ +++A ++T ++N
Sbjct: 480 KSCT------ESPVNCLPSFQQPLKPNLL---FSDNDVFKSNALVVTLLLSN-------H 523
Query: 558 NGKAIAWEK 566
+ A+ WEK
Sbjct: 524 SNSALLWEK 532
>Q9VL24_DROME (tr|Q9VL24) Niemann-Pick type C-1a, isoform A OS=Drosophila
melanogaster GN=Npc1a PE=4 SV=2
Length = 1287
Score = 173 bits (439), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 146/592 (24%), Positives = 242/592 (40%), Gaps = 90/592 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPH----DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C NCPY + + +LL + L CC + Q
Sbjct: 29 SKQDCVWYGVCNTNDFSHSQNCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A IL CP+C+ N + C+ +CSP Q+ F++V + + G+ + +
Sbjct: 89 VELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMHVVATQKNKKGDEYISSV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+++ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P +N + CN
Sbjct: 208 ------FQITYIQHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ L VLVF++ GS L ++G S
Sbjct: 262 PRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVID-PQRQNEVQY----SFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
N DG + + P +N+ + + + +L F+ +G + A P + L + +
Sbjct: 303 MDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGAS 362
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII--ATLPESE 426
+V++L +G+ + T P KLW P SK+ E+EFFD+ +PFYR+EQ+II LP+
Sbjct: 363 LVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIV 422
Query: 427 HGKPPS------IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------ 474
H + + + + ++QE + EI AN + L DIC PL +D
Sbjct: 423 HNTSNGPYTFGPVFDREFLTKVLDLQEGIKEINANGT----QLKDICYAPLSDDGSEIDV 478
Query: 475 --CATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTAL 527
C QSI YF ++D + DN V + + + ++ C + + P++P AL
Sbjct: 479 SQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIAL 538
Query: 528 GGF--------SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GGF + A+A I+T+ V N K EN A+ WEK F++
Sbjct: 539 GGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKTDLEN--ALTWEKKFVEF 588
>J8Q0Y3_SACAR (tr|J8Q0Y3) Ncr1p OS=Saccharomyces arboricola (strain H-6 / AS
2.3317 / CBS 10644) GN=SU7_3612 PE=4 SV=1
Length = 1170
Score = 173 bits (439), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 136/545 (24%), Positives = 248/545 (45%), Gaps = 65/545 (11%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITG-- 85
Q+ + + + CAMY CG++S G L CP PS +P LS + L + G
Sbjct: 10 VGQLIQLVQATGTCAMYGNCGKKSIFGTELPCP-AQPSFEP-PALSDETSKLLVEVCGEE 67
Query: 86 -----NVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
+ CCT++Q+ +A P++ CPACL+NF NLFC +C+P+Q +F+N+T +
Sbjct: 68 WKEVRHTCCTKDQVVALRDNLQKAQPLIASCPACLKNFNNLFCHFTCAPDQGMFVNITKV 127
Query: 133 SQVDGNM-TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLG 191
+ + + V +D+++ ++ Y +CK++KF N A+D +G GA NY ++ FLG
Sbjct: 128 GKSNEDKDIVAELDVFMNASWASQFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFLG 187
Query: 192 QKVPPGFPGSPYSIDFKTTI-LDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXX 250
P GSP+ I++K + + + N VY+C+D
Sbjct: 188 D-AKPMLGGSPFQINYKYDLPSEEEGWQEFNDVVYACDDPQ-----------YKCACSDC 235
Query: 251 XXXXXXXXXIKMGSLKVR---CVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPL 307
+K G+ KV C S+ + Y V + W + L
Sbjct: 236 QESCPDLAPLKGGTCKVGILPCFSFSVVIFYTVCTLIAATWYFLFRRKENGALIMDDDIL 295
Query: 308 LVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
SE +N+ D + + L+N + +++ + P VL ++
Sbjct: 296 PESESLDNSNM---------DVFENFNSNSNSFNDKLANLFSKVAQFSVQNPYKVLTATA 346
Query: 368 AIVILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESE 426
+ F + R+ ++ET P LWV S+ +EK++FD + PFYR EQ+ + +E
Sbjct: 347 LGIFAFGFIIFRYGSLETDPINLWVSKNSEKFKEKKYFDDNFGPFYRTEQIFVV----NE 402
Query: 427 HGKPPSIVTDDNIELLFEIQEKV-DEIRANYSGLLVSLSDICLKPLGED-CATQSILQYF 484
G +++ + ++ F++++ + +E++++ + V D+C +P + C +S QYF
Sbjct: 403 TG---PVLSYETLDWWFDVEKFITEELQSSEN---VGYQDLCFRPTDDSTCVIESFTQYF 456
Query: 485 QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIIT 544
Q D++ + C + + C F+ PL+ FS ++ A AF++T
Sbjct: 457 QGVLPGKDSWKA--ELKTCGKFPVN---CLPTFQQPLKTNLL---FSDDDVLNAHAFVVT 508
Query: 545 YPVNN 549
+ N
Sbjct: 509 LLLTN 513
>Q7YU59_DROME (tr|Q7YU59) RE56428p OS=Drosophila melanogaster GN=Npc1a PE=2 SV=1
Length = 1287
Score = 173 bits (439), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 146/592 (24%), Positives = 242/592 (40%), Gaps = 90/592 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPH----DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C NCPY + + +LL + L CC + Q
Sbjct: 29 SKQDCVWYGVCNTNDFSHSQNCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A IL CP+C+ N + C+ +CSP Q+ F++V + + G+ + +
Sbjct: 89 VELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMHVVATQKNKKGDEYISSV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+++ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P +N + CN
Sbjct: 208 ------FQITYIQHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ L VLVF++ GS L ++G S
Sbjct: 262 PRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVID-PQRQNEVQY----SFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
N DG + + P +N+ + + + +L F+ +G + A P + L + +
Sbjct: 303 MDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGAS 362
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII--ATLPESE 426
+V++L +G+ + T P KLW P SK+ E+EFFD+ +PFYR+EQ+II LP+
Sbjct: 363 LVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIV 422
Query: 427 HGKPPS------IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------ 474
H + + + + ++QE + EI AN + L DIC PL +D
Sbjct: 423 HNTSNGPYTFGPVFDREFLTKVLDLQEGIKEINANGT----QLKDICYAPLSDDGSEIDV 478
Query: 475 --CATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTAL 527
C QSI YF ++D + DN V + + + ++ C + + P++P AL
Sbjct: 479 SQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIAL 538
Query: 528 GGF--------SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GGF + A+A I+T+ V N K EN A+ WEK F++
Sbjct: 539 GGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKTDLEN--ALTWEKKFVEF 588
>Q9U5W1_DROME (tr|Q9U5W1) NPC1 protein OS=Drosophila melanogaster GN=Npc1a PE=2
SV=1
Length = 1287
Score = 173 bits (439), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 146/592 (24%), Positives = 242/592 (40%), Gaps = 90/592 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPH----DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C NCPY + + +LL + L CC + Q
Sbjct: 29 SKQDCVWYGVCNTNDFSHSQNCPYNGTAKEMATDGLELLKKRCGFLLENSENKFCCDKNQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A IL CP+C+ N + C+ +CSP Q+ F++V + + G+ + +
Sbjct: 89 VELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMHVVATQKNKKGDEYISSV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+++ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P +N + CN
Sbjct: 208 ------FQITYIQHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ L VLVF++ GS L ++G S
Sbjct: 262 PRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVID-PQRQNEVQY----SFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
N DG + + P +N+ + + + +L F+ +G + A P + L + +
Sbjct: 303 MDDNFQVDGNDVSDEMPYSENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGAS 362
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII--ATLPESE 426
+V++L +G+ + T P KLW P SK+ E+EFFD+ +PFYR+EQ+II LP+
Sbjct: 363 LVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIV 422
Query: 427 HGKPPS------IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------ 474
H + + + + ++QE + EI AN + L DIC PL +D
Sbjct: 423 HNTSNGPYTFGPVFDREFLTKVLDLQEGIKEINANGT----QLKDICYAPLSDDGSEIDV 478
Query: 475 --CATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTAL 527
C QSI YF ++D + DN V + + + ++ C + + P++P AL
Sbjct: 479 SQCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIAL 538
Query: 528 GGF--------SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GGF + A+A I+T+ V N K EN A+ WEK F++
Sbjct: 539 GGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKTDLEN--ALTWEKKFVEF 588
>G3S497_GORGO (tr|G3S497) Uncharacterized protein OS=Gorilla gorilla gorilla
GN=NPC1L1 PE=4 SV=1
Length = 1332
Score = 173 bits (439), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 162/611 (26%), Positives = 255/611 (41%), Gaps = 115/611 (18%)
Query: 36 IHSNEYCAMYDICGQRSD--GKVL-----NCPYPSPSVKPHDLLSAKIQSLCPTI-TG-- 85
IH YCA YD CG+ + G ++ +C +P+ K +Q +CP + TG
Sbjct: 27 IHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGPN 86
Query: 86 -NVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
CC+ +QL ++ +L CPAC NF+NL C +CSPNQSLFINVT ++Q+
Sbjct: 87 TQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQLG 146
Query: 137 GNM--TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFL 190
V + + +F E Y +C V+ T A+ + G+ N + W F
Sbjct: 147 AGQLPAVVAYEAFYQHSFAERSYDSCSRVRIPAAATLAVGTMCGVYGSALCNAQRWLNFQ 206
Query: 191 GQKVPPGFPGSPYSIDFKTTILD-----SSPMELMNASVYSCNDTSLGXXXXXXXXXXXX 245
G G +P I F +L+ S ++ +N V CN++
Sbjct: 207 GDT---GNGLAPLDITFH--LLEPGQAVGSGIQPLNEGVARCNESQGDDVAACSCQDCAA 261
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAE 305
+G + S +++ I+++ +F +
Sbjct: 262 SCPAIARPHALDSTFYLGRM-------SGSLVLIIILCSIFAVVTI-------------- 300
Query: 306 PLLVSEGRSFTNLPKDGEVLVIDPQRQNEV--QYSF-IQEWLSNFYRAYGRWAARRPTIV 362
LLV F P + +DP++ + + SF L F++ +G W A P +
Sbjct: 301 -LLVG----FRVAPARDKSKTVDPKKGTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLTI 355
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATL 422
L S+ V+ L GL+ + T P +LW P S+A EK F D H PF+R Q+I+ T
Sbjct: 356 LVLSVIPVVALAAGLVFTELTTDPVELWSAPSSQARSEKAFHDQHFGPFFRTNQVIL-TA 414
Query: 423 PESEHGKPPSIVTDDNI-----------------ELLFEIQEKVDEIRANYSGLLVSLSD 465
P + S++ E L +Q E + N +SL D
Sbjct: 415 PNRSSYRYDSLLLGPKTFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-----ISLQD 469
Query: 466 ICLKPLGE------DCATQSILQYFQMDP------------------DNFDNYGGVEHAE 501
IC PL DC S+LQYFQ + D D++ +A
Sbjct: 470 ICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAP 529
Query: 502 YCFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN-G 559
F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN GD
Sbjct: 530 LTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNN--YPAGDPRLA 587
Query: 560 KAIAWEKAFIQ 570
+A WE+AF++
Sbjct: 588 QAKLWEEAFLE 598
>H0H292_9SACH (tr|H0H292) Ncr1p OS=Saccharomyces cerevisiae x Saccharomyces
kudriavzevii VIN7 GN=VIN7_10442 PE=4 SV=1
Length = 1073
Score = 172 bits (437), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 138/543 (25%), Positives = 246/543 (45%), Gaps = 62/543 (11%)
Query: 29 AAQISRSIHSNEYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITG-- 85
AQ+ + + + CAMY CG++S G L CP P +LS + L + G
Sbjct: 10 VAQLIQLVQATGTCAMYGNCGKKSIFGSELPCPAKIGFEPP--VLSDETSKLLVEVCGEE 67
Query: 86 -----NVCCTEEQL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSI 132
N CCTE+Q+ +A P++ CPACL+NF NLFC +C+P+Q FIN+T +
Sbjct: 68 WKDIRNACCTEDQVLALRDNLQRAQPLISSCPACLKNFNNLFCHFTCAPDQGTFINITKV 127
Query: 133 SQV-DGNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLG 191
+ D V +D++++ ++ Y +CK++KF N A+D +G GA NY ++ FLG
Sbjct: 128 ERSKDDKDIVAELDVFMSSSWATEFYDSCKNIKFSATNGYAMDLIGGGAKNYSQFLKFLG 187
Query: 192 QKVPPGFPGSPYSIDFKTTILDSSP-MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXX 250
P GSP+ I++K + + + N VY+C+D
Sbjct: 188 D-AKPMLGGSPFQINYKYDLPEGEKEWQEFNEEVYACDDAQY------KCACTDCQESCP 240
Query: 251 XXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVS 310
K+GSL C S+ + Y + W + ++
Sbjct: 241 DLAPLKDGTCKVGSLP--CFSFSVVIFYTICALFAATWYLCKSKENGALI---VDDDILP 295
Query: 311 EGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIV 370
E S N D V N I + ++N ++ +++ + P +L ++ +
Sbjct: 296 ESASLDN--SDTNVFENFNNESNS-----INDKVANLFKKVAQFSVQNPYKILTATAFSI 348
Query: 371 ILLCFGLLRF-NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGK 429
+ F + ++ +ET P LWV S+ +EKE+FD++ PFYR EQ+ + +E G
Sbjct: 349 LAFGFIIFQYGTLETDPINLWVSKNSEKFKEKEYFDNNFGPFYRTEQIFVV----NETG- 403
Query: 430 PPSIVTDDNIELLFEIQEKVD-EIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQ-M 486
+++ + ++ F++++ + E++++ + + D+C +P + C +S QYFQ +
Sbjct: 404 --PVLSYETLDWWFDVEKFITGELQSSEN---IGYQDLCFRPTEDSTCVIESFTQYFQGV 458
Query: 487 DPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYP 546
P D + C + + C F+ PL+ FS ++ A AF++T
Sbjct: 459 LP---DKNSWERELQACGKFPVN---CLPTFQQPLKTNLL---FSDDDILNAHAFVVTLL 509
Query: 547 VNN 549
+ N
Sbjct: 510 LTN 512
>G1QUH0_NOMLE (tr|G1QUH0) Uncharacterized protein OS=Nomascus leucogenys
GN=NPC1L1 PE=4 SV=1
Length = 1332
Score = 172 bits (437), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 161/611 (26%), Positives = 253/611 (41%), Gaps = 115/611 (18%)
Query: 36 IHSNEYCAMYDICGQRSD--GKVL-----NCPYPSPSVKPHDLLSAKIQSLCPTI-TG-- 85
IH YCA YD CG+ + G ++ +C +P+ K +Q +CP + TG
Sbjct: 27 IHQPGYCAFYDECGKNPELSGGLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGPN 86
Query: 86 -NVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
CC+ +QL ++ +L CPAC NF+NL C +CSPNQSLFINVT ++Q+
Sbjct: 87 TQACCSAKQLVSLEASMSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQLR 146
Query: 137 GNM--TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFL 190
V + + +F E Y +C V+ T A+ + G+ N + W F
Sbjct: 147 AGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNFQ 206
Query: 191 GQKVPPGFPGSPYSIDFKTTILD-----SSPMELMNASVYSCNDTSLGXXXXXXXXXXXX 245
G G +P I F +L+ S ++ +N V CN++
Sbjct: 207 GDT---GNGLAPLDITFH--LLEPGQAVGSGIQPLNEGVARCNESQGDDVVACSCQDCAA 261
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCV-DLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSA 304
+G + R V + L ++ V+ +L G
Sbjct: 262 SCPAIARPQALDSTFYLGRMPGRLVLIIILCSVFAVVTILLLG----------------- 304
Query: 305 EPLLVSEGRSFTNLPKDGEVLVIDPQRQNEV--QYSF-IQEWLSNFYRAYGRWAARRPTI 361
L V+ R + +D ++ + + SF L F++ +G W A P
Sbjct: 305 --LRVAPARDKSK--------TVDAKKSTSLSDKLSFSTHTLLGQFFQGWGTWVASWPLT 354
Query: 362 VLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT 421
+L S+ V+ L GL+ + T P +LW P S+A EK F D H PF+R Q+I+
Sbjct: 355 ILVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTA 414
Query: 422 LPESEHGKPPSIVTDDNI----------------ELLFEIQEKVDEIRANYSGLLVSLSD 465
S + ++ N E L +Q + E + N +SL D
Sbjct: 415 PNRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWLPEAQRN-----ISLRD 469
Query: 466 ICLKPLGE------DCATQSILQYFQMDP------------------DNFDNYGGVEHAE 501
IC PL DC S+LQYFQ + D D++ +A
Sbjct: 470 ICYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAP 529
Query: 502 YCFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN-G 559
F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN GD
Sbjct: 530 LTFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNN--YPAGDPRLA 587
Query: 560 KAIAWEKAFIQ 570
+A WE+AF++
Sbjct: 588 QAKLWEEAFLE 598
>B4Q8Q7_DROSI (tr|B4Q8Q7) GD22294 OS=Drosophila simulans GN=Dsim\GD22294 PE=4
SV=1
Length = 1251
Score = 172 bits (437), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 147/592 (24%), Positives = 240/592 (40%), Gaps = 90/592 (15%)
Query: 38 SNEYCAMYDICGQRSDGKVLNCPYPSPSVKPH----DLLSAKIQSLCPTITGNVCCTEEQ 93
S + C Y +C NCPY + + LL + L CC + Q
Sbjct: 29 SKQDCVWYGVCNTNEYSHSQNCPYNGTAKEMAADGLQLLKKRCGFLLENSENKFCCDKNQ 88
Query: 94 LQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQ-VDGNMTVDGI 144
++ A IL CP+C+ N + C+ +CSP Q+ F++V + + G+ + +
Sbjct: 89 VELLNKNVELAGNILDRCPSCMENLVRHICQFTCSPKQAEFMHVVATQKNKKGDEYISSV 148
Query: 145 DLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQKVPPGFPG 200
DL+++ + Y +C V A D + A N +WF F+G P P
Sbjct: 149 DLHISTEYINKTYKSCSQVSVPQTGQLAFDLMCGAYSASRCNPTKWFNFMGDATNPYVP- 207
Query: 201 SPYSIDFKTTILDSSP------MELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXX 254
F+ T + P +N + CN
Sbjct: 208 ------FQITYIQHEPKSNSNNFTPLNVTTVPCNQAVSSKLPACSCSDCDLSCPQGPPEP 261
Query: 255 XXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRS 314
K+ L V ++ L VLVF++ GS L ++G S
Sbjct: 262 HRPEPFKIVGLDAYFVIMAAVFLVGVLVFLM---------------GS----FLFTQGSS 302
Query: 315 FT-NLPKDGEVLVID-PQRQNEVQY----SFIQEWLSNFYRAYGRWAARRPTIVLCSSLA 368
N DG + P +N+ + + + +L F+ +G + A P + L + +
Sbjct: 303 MDDNFQVDGNDASDEMPYNENDSYFEKLGAHTETFLETFFTKWGTYFASNPGLTLIAGAS 362
Query: 369 IVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLII--ATLPESE 426
+V++L +G+ + T P KLW P SK+ E+EFFD+ +PFYR+EQ+II LP+
Sbjct: 363 LVVILGYGINFIEITTDPVKLWASPNSKSRLEREFFDTKFSPFYRLEQIIIKAVNLPQIV 422
Query: 427 HGKPPS------IVTDDNIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED------ 474
H + D + + ++QE + EI AN + L DIC PL +D
Sbjct: 423 HNTSNGPYTFGPVFDRDFLSKVLDLQEGIKEINANGT----QLKDICYAPLSDDGSEIDV 478
Query: 475 --CATQSILQYF-----QMDPDNFDNYGGVEHAEYCFQHYTSTETCFSAFKAPLEPTTAL 527
C QSI YF ++D + DN V + + + ++ C + + P++P AL
Sbjct: 479 SKCVVQSIWGYFGDDRERLDDHDEDNGFNVTYLDALYDCISNPYLCLAPYGGPVDPAIAL 538
Query: 528 GGF--------SGNNYSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQL 571
GGF + A+A I+T+ V N K EN A+ WEK F++
Sbjct: 539 GGFLPPGDQLTGSTKFELANAIILTFLVKNHHNKTDLEN--ALTWEKKFVEF 588
>K7FGY8_PELSI (tr|K7FGY8) Uncharacterized protein OS=Pelodiscus sinensis GN=NPC1
PE=4 SV=1
Length = 1214
Score = 172 bits (437), Expect = 3e-40, Method: Compositional matrix adjust.
Identities = 139/512 (27%), Positives = 223/512 (43%), Gaps = 56/512 (10%)
Query: 103 CPACLRNFLNLFCELSCSPNQSLFINVT-SISQVD-----GNMTVDGIDLYVTETFGEGL 156
CP+C N +NLFCEL+CSP+Q F+NVT +I D ++ ++ Y+ E+F +
Sbjct: 12 CPSCFYNLINLFCELTCSPHQVHFLNVTKTIPYYDPVTKENKTSITELEYYIGESFANAM 71
Query: 157 YSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPGFPGSPYSIDFKTTILD 213
Y+ACKDV+ + N +A+ + G N W ++ K +P+SI + +
Sbjct: 72 YNACKDVEAPSSNDKALGLLCGKDVKDCNATNWIQYMFSKENGQ---TPFSIIPFFSDIS 128
Query: 214 SSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCVDLS 273
M MN + CN+++ + L V +
Sbjct: 129 LHGMSPMNNATKGCNESTDDVTGPCSCQDCSIVCGPKPEPPPPAAPWLLLGLDAIYVIMW 188
Query: 274 LAVLYIVLVF--VLFG-WIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVLVIDPQ 330
++ + +LVF V+FG W + R + GE L +
Sbjct: 189 ISYMGFLLVFFAVIFGVWCYRKRHFVSEYTPIDSNIAFSVNSRHDSGEASCGERL--GER 246
Query: 331 RQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETRPEKLW 390
+N ++ +F+ ++G + R P V+ S+ V + C GL+ + T P LW
Sbjct: 247 FENCLRLTFM---------SWGAFCVRNPRPVVLFSVVFVAMCCSGLMYIKITTNPVDLW 297
Query: 391 VGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD-------NIELLF 443
P S+A +EK++FD++ PF+R EQLII H P +D + ++L+
Sbjct: 298 SSPNSQARKEKQYFDTYFGPFFRTEQLIIRAPHSKPHIYSPYPSGNDVPFGPPLDKDILY 357
Query: 444 EI---QEKVDEIRANYSGLLVSLSDICLKPLG---EDCATQSILQYFQMDPDNFDNYGGV 497
++ Q ++ I A+Y V L DICL PL +C S+L YFQ ++ G
Sbjct: 358 QVLDLQNAIENITASYDNETVMLKDICLAPLAPYNNNCTILSVLNYFQNSYSVLNHSVGD 417
Query: 498 E---------HAEYCFQHYTST-------ETCFSAFKAPLEPTTALGGFSGNNYSEASAF 541
E H YC + S + C F P+ P LGG+ G NY+ A+A
Sbjct: 418 EFFVFADYHTHFLYCVRAPASLNDTSQLHDPCLGTFGGPVFPWLVLGGYDGENYNNATAL 477
Query: 542 IITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
+IT+PV N + +A+AWEK FI K
Sbjct: 478 VITFPVRNYYNDT-HKLMRALAWEKEFISFVK 508
>H2R5C0_PANTR (tr|H2R5C0) Uncharacterized protein OS=Pan troglodytes GN=NPC1L1
PE=4 SV=1
Length = 1359
Score = 172 bits (436), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 161/610 (26%), Positives = 253/610 (41%), Gaps = 113/610 (18%)
Query: 36 IHSNEYCAMYDICGQRSD--GKVL-----NCPYPSPSVKPHDLLSAKIQSLCPTI-TG-- 85
IH YCA YD CG+ + G ++ +C +P+ K +Q +CP + TG
Sbjct: 27 IHQPGYCAFYDECGKNPELSGSLMTLSNVSCLSNTPARKITGDHLILLQKICPRLYTGPN 86
Query: 86 -NVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
CC+ +QL ++ +L CPAC NF+NL C +CSPNQSLFINVT ++Q+
Sbjct: 87 TQACCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINVTRVAQLG 146
Query: 137 GNM--TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFL 190
V + + +F E Y +C V+ T A+ + G+ N + W F
Sbjct: 147 AGQLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCGVYGSALCNAQRWLNFQ 206
Query: 191 GQKVPPGFPGSPYSIDFKTTILD-----SSPMELMNASVYSCNDTSLGXXXXXXXXXXXX 245
G G +P I F +L+ S ++ +N V CN++
Sbjct: 207 GDT---GNGLAPLDITFH--LLEPGQAVGSGIQPLNEGVARCNESQGDDVVACSCQDCAA 261
Query: 246 XXXXXXXXXXXXXXIKMGSLKVRCV-DLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSA 304
+G + V + L ++ V+ +L G+
Sbjct: 262 SCPAIARPQALDSTFYLGQMPGSLVLIIILCSVFAVVTILLVGF---------------- 305
Query: 305 EPLLVSEGRSFTNL--PKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV 362
V+ R + + PK G L +++ +S L F++ +G W A P +
Sbjct: 306 ---RVAPARDKSKMADPKKGTSL------SDKLSFS-THTLLGQFFQGWGTWVASWPLTI 355
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATL 422
L S+ V+ L GL+ + T P +LW P S+A EK F D H PF+R Q+I+
Sbjct: 356 LVLSVIPVVALAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAP 415
Query: 423 PESEHGKPPSIVTDDNI----------------ELLFEIQEKVDEIRANYSGLLVSLSDI 466
S + ++ N E L +Q E + N +SL DI
Sbjct: 416 NRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-----ISLQDI 470
Query: 467 CLKPLGE------DCATQSILQYFQMDP------------------DNFDNYGGVEHAEY 502
C PL DC S+LQYFQ + D D++ +A
Sbjct: 471 CYAPLNPDNTSLYDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWKDHFLYCANAPL 530
Query: 503 CFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN-GK 560
F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN GD +
Sbjct: 531 TFKDGTALALSCMADYGAPVFPFLAIGGYKGKDYSEAEALIMTFSLNN--YPAGDPRLAQ 588
Query: 561 AIAWEKAFIQ 570
A WE+AF++
Sbjct: 589 AKLWEEAFLE 598
>G3WDA4_SARHA (tr|G3WDA4) Uncharacterized protein (Fragment) OS=Sarcophilus
harrisii GN=NPC1 PE=4 SV=1
Length = 1192
Score = 172 bits (435), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 148/517 (28%), Positives = 217/517 (41%), Gaps = 64/517 (12%)
Query: 103 CPACLRNFLNLFCELSCSPNQSLFINVTSI-SQVD-----GNMTVDGIDLYVTETFGEGL 156
CP+C N +NLFCEL+CSP QS F+NVT+ S +D V+ + Y+ ++F + +
Sbjct: 9 CPSCFYNLMNLFCELTCSPRQSQFLNVTATKSYIDPTTNETKTNVEELQYYIGQSFADAM 68
Query: 157 YSACKDVKFGTMNTRAIDFV-GAGAN--NYKEWFAFLGQKVPPGFPGSPYSIDFKTTILD 213
Y+AC+DV+ + N +A+ + G A N W ++ K P + I ++
Sbjct: 69 YNACRDVESPSSNDKALGLLCGKDAKDCNATNWIEYMFNKNNGQAPFNIIPIFSDNSLYK 128
Query: 214 SSPMELMNASVYSCN---DTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXIKMGSLKVRCV 270
ME MN + CN D G + ++ V
Sbjct: 129 ---MEPMNNATKGCNESVDDVTGPCSCQDCSITCGPKPQPPPPPVPWLIFGLDAMYV--- 182
Query: 271 DLSLAVLYIVLVFVLFG-----WIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPKDGEVL 325
+ + Y+ + V FG W A LL S S LP GE
Sbjct: 183 --IMWIFYMGFLLVFFGMFFIVWCYSLLTSFLLQISGMAW-LLTSNLPSSPALP--GEAS 237
Query: 326 VIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRFNVETR 385
D R V + L+ + +G + R P V+ SL + + GL+ + T
Sbjct: 238 CGD--RLGAV----FESCLTQGFTRWGSFCVRNPVPVIICSLFFIAVCSSGLVFMRLATN 291
Query: 386 PEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDDN------- 438
P LW P S+A EKE+FD+H PF+R EQLII H P D
Sbjct: 292 PVDLWSAPNSQAHLEKEYFDTHFGPFFRTEQLIIQAPHTKGHIYQPYPSGADVPFGPPLD 351
Query: 439 ---IELLFEIQEKVDEIRANYSGLLVSLSDICLKPL---GEDCATQSILQYFQMDPDNFD 492
+ + ++Q ++ I A+Y+ V+L DICL PL +C S+L YFQ D
Sbjct: 352 KGILHQVLDLQTAIENITASYNNETVTLEDICLAPLSPYNNNCTILSVLNYFQNSHSVLD 411
Query: 493 NYGGVE---------HAEYCFQHYTST-------ETCFSAFKAPLEPTTALGGFSGNNYS 536
+ G E H YC + S ++C F P+ P LGG+ NY+
Sbjct: 412 HQKGDEFFVYADYHTHFLYCTRAPASLNDTSLLHDSCLGTFGGPIFPWLVLGGYDDQNYN 471
Query: 537 EASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
A+A +IT PVNN ++ KA AWEK FI K
Sbjct: 472 NATALVITLPVNNYYNNT-EKLQKAQAWEKEFISFVK 507
>J7S5U3_KAZNA (tr|J7S5U3) Uncharacterized protein OS=Kazachstania naganishii
(strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC
22969 / KCTC 17520 / NBRC 10181 / NCYC 3082)
GN=KNAG0D02600 PE=4 SV=1
Length = 1191
Score = 171 bits (434), Expect = 5e-40, Method: Compositional matrix adjust.
Identities = 138/533 (25%), Positives = 239/533 (44%), Gaps = 60/533 (11%)
Query: 40 EYCAMYDICGQRSD-GKVLNCPYPSPSVKPHDLLSAKIQSLCPTITG-------NVCCTE 91
+ CAMY CG+++ G L CP S ++ ++ L G NVCC+
Sbjct: 21 QQCAMYGNCGKKTPLGVELPCPVDRTSPLQPPGITNDLRDLLVLTCGEEWKEIENVCCSI 80
Query: 92 EQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINV--TSISQVDGNMTV 141
EQ++A+ ++ CPAC++NF N+FC +CSP Q+ F++V T +SQ + V
Sbjct: 81 EQVKALQNNLKRAHALIESCPACVKNFNNMFCHFTCSPQQASFLDVIDTEVSQ-ENKRIV 139
Query: 142 DGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFVGAGANNYKEWFAFLG-QKVPPGFPG 200
++ Y+ E + +++CK++KF N A+D +G GA NY E+ FLG +K G G
Sbjct: 140 KELNFYMDEDWASEFFNSCKNIKFSATNGYAMDLIGGGARNYSEFLQFLGDEKALLG--G 197
Query: 201 SPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXXXXXXXXXI 260
SP+ I++K + + N SVY C+D
Sbjct: 198 SPFQINYKYA--QTKKFQPFNNSVYGCDDP-----IYKCACSDCQESCPVLKPLKQEHCF 250
Query: 261 KMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEPLLVSEGRSFTNLPK 320
+ G C + + + Y+++ L W + L++ + P+
Sbjct: 251 RNG---FPCFSIDVLITYVIIAVTLLIWFIVKKWKSNDIQNTDQ---LLNPSAGQDSSPE 304
Query: 321 DGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSLAIVILLCFGLLRF 380
D ++ +++ ++ +S + A P IVLC L +I+L FG+L F
Sbjct: 305 D---MLFQDRKKTKLYKP--NSLISKAVESVANIAVYHPYIVLC--LTSIIILSFGVLLF 357
Query: 381 ---NVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATLPESEHGKPPSIVTDD 437
++E P LWV S +EK++FD H PFYR+EQ+ + + P +
Sbjct: 358 FFGSLEQDPVNLWVSKSSPKYKEKQYFDEHFGPFYRVEQIFVV------NDTGPVLSNYS 411
Query: 438 NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-CATQSILQYFQMDPDNFDNYGG 496
+E FE+++++ E + GL + D+C +P + C +S QYF+ + +
Sbjct: 412 TLEWWFEVEKQMTESLTSSEGL--TYQDLCFRPTPDSTCVVESFTQYFKGEIPKKSFWES 469
Query: 497 VEHAEYCFQHYTSTETCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNN 549
+ C + TC F+ PL+ S ++ +++AFI+T VNN
Sbjct: 470 --QIKMC---ANTPVTCLPTFQQPLKKNLLFSDLS-DDVLQSNAFIVTLLVNN 516
>E0VVZ7_PEDHC (tr|E0VVZ7) Niemann-Pick C1 protein, putative OS=Pediculus humanus
subsp. corporis GN=Phum_PHUM472470 PE=4 SV=1
Length = 1278
Score = 168 bits (425), Expect = 6e-39, Method: Compositional matrix adjust.
Identities = 162/593 (27%), Positives = 241/593 (40%), Gaps = 94/593 (15%)
Query: 44 MYDICGQRSDG---KVLNCPYPSPSVKPHDLLSAKIQSLCPTITGNV--------CCTEE 92
MY CG+ + ++L C Y + D ++ CP + CC E
Sbjct: 1 MYGECGKAQNAPAAQLLPCSYNGTAKVLSDKGIKVLKKWCPHYFDSTSDSQLIYTCCDEA 60
Query: 93 QL--------QAVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVDGNMT---- 140
QL QA+ ++ CP+C NF+ +C+ +C P+QS FI I N +
Sbjct: 61 QLETLDKNIQQAMMLISRCPSCKYNFVRHYCDFTCRPDQSNFIEPLRIVNATLNKSAGYR 120
Query: 141 --VDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV---GAGANNYKEWFAFLGQKVP 195
V I+LY+ +++ G Y +CK+V N A+D + + + + WF FLG
Sbjct: 121 PAVSEINLYINKSYTYGTYDSCKNVYLPLANQYAMDLLCNRPVVSCSPELWFEFLGDA-- 178
Query: 196 PGFPGSPYSIDFKTTILDSSPMEL----MNASVYSCNDTSLGXXXXXXXXXXXXXXXXXX 251
F SPY I++ I+ S E +N YSCN+ L
Sbjct: 179 SAF--SPYQINY---IMSSKAKEKNFTPLNIKTYSCNEAPLENESACSCVDCVESCPIPP 233
Query: 252 XXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP----L 307
+G+L R D + +++I + + S P
Sbjct: 234 PVPSPVAPFFVGALPGR--DFVMLLVFIAGSLIFLSIVLFCNKRNRQQGASEGNPNEKTE 291
Query: 308 LVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIVLCSSL 367
V S + + K G I+++L F+ G RP +VL + L
Sbjct: 292 FVGTKSSLSKIEKAGAA---------------IEKFLERFFYKLGMLCVSRPWLVLLTGL 336
Query: 368 AIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIAT--LPES 425
+ I L G+L V T P +LW P S++ EKE++DS+ PFYR EQ+II LP
Sbjct: 337 LVFICLACGILFVKVTTDPIELWANPLSRSRVEKEYYDSNFRPFYRTEQIIIHAVGLPNI 396
Query: 426 EHGKPPSIVTDD---NIELLFEIQEKVDEIRANYSGLLVSLSDICLKPLGED-------- 474
H VT N+ L +I + IR N + V+L DIC PL D
Sbjct: 397 THNTSLGPVTFGPVFNVSFLKKIYDLEQSIR-NLNADGVTLKDICFSPLSSDSGPEDVSQ 455
Query: 475 CATQSILQYFQMDPDNFDNYGGVEHAEY------CFQHYTSTETCFSAFKAPLEPTTALG 528
C+ SI Y+Q D N D E EY C + + C + + P+ P ALG
Sbjct: 456 CSIMSIWGYYQDDLSNLD----TEDDEYLNRFMSCVNNPYLPDECLAPWGGPILPDLALG 511
Query: 529 GF--SGNN------YSEASAFIITYPVNNALTKVGDENGKAIAWEKAFIQLAK 573
GF +G N Y ++ I+TY V+N K E A+ WE FI+L K
Sbjct: 512 GFLEAGLNEKGKPKYELSTTLILTYLVDNHHNKTLRE--PALKWEARFIELLK 562
>F6U2U0_MACMU (tr|F6U2U0) Uncharacterized protein OS=Macaca mulatta GN=NPC1L1
PE=2 SV=1
Length = 724
Score = 168 bits (425), Expect = 7e-39, Method: Compositional matrix adjust.
Identities = 160/610 (26%), Positives = 252/610 (41%), Gaps = 113/610 (18%)
Query: 36 IHSNEYCAMYDICGQRSD--GKVL-----NCPYPSPS---VKPHDLLSAKIQSLCPTI-T 84
IH YCA YD CG+ + G ++ +C +P+ H +L +Q +CP + T
Sbjct: 27 IHQPGYCAFYDECGKNPELSGGLMTLSNVSCLSNTPARNITGDHLIL---LQRICPRLYT 83
Query: 85 G---NVCCTEEQLQAV--------PILVGCPACLRNFLNLFCELSCSPNQSLFINVTSIS 133
G CC+ +QL ++ +L CPAC NF++L C +CSPNQSLFINVT ++
Sbjct: 84 GPNTQACCSAKQLVSLEASLSITKALLTRCPACSDNFVSLHCHNTCSPNQSLFINVTRVA 143
Query: 134 QVDGNM--TVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWF 187
Q+ V + + +F E Y +C V T A+ + G+ N + W
Sbjct: 144 QLGAGQLPAVVAYEAFYQHSFAEQSYDSCSRVHIPAAATLAVGSMCGVYGSALCNAQRWL 203
Query: 188 AFLGQKVPPGFPGSPYSIDFKTTILD-----SSPMELMNASVYSCNDTSLGXXXXXXXXX 242
F G G +P I F +L+ S ++ +N V CN++
Sbjct: 204 NFQGDT---GNGLAPLDITFH--LLEPGQAVGSGIQPLNEGVARCNESQGDDAVACSCQD 258
Query: 243 XXXXXXXXXXXXXXXXXIKMGSLKVRCVDLSLAVLYIVLVFVLFGWIXXXXXXXXXXXGS 302
++G + V + + +V +L G
Sbjct: 259 CAASCPAIAHPQALDSTFRLGRMPGGLVLIIILCSVFTVVAILL-------------VGL 305
Query: 303 SAEPLLVSEGRSFTNLPKDGEVLVIDPQRQNEVQYSFIQEWLSNFYRAYGRWAARRPTIV 362
P + +S T PK G L +++ +S L F++ +G W A P +
Sbjct: 306 RVAP---TRDKSKTVDPKKGTSL------SDKLSFS-THTLLGQFFQGWGTWVASWPLTI 355
Query: 363 LCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLIIATL 422
L S+ V++L GL+ + T P +LW P S+A EK F D H PF+R Q+I+
Sbjct: 356 LVLSVIPVVVLAAGLVFTELTTDPVELWSAPNSQARSEKAFHDQHFGPFFRTNQVILTAP 415
Query: 423 PESEHGKPPSIVTDDNI----------------ELLFEIQEKVDEIRANYSGLLVSLSDI 466
S + ++ N E L +Q E + N +SL I
Sbjct: 416 NRSSYRYDSLLLGPKNFSGILDLDLLLELLELQERLRHLQVWSPEAQRN-----ISLQHI 470
Query: 467 CLKPLG------EDCATQSILQYFQMDP------------------DNFDNYGGVEHAEY 502
C PL DC S+LQYFQ + D D++ +A
Sbjct: 471 CYAPLNPDNTSLSDCCINSLLQYFQNNRTLLLLTANQTLMGQTSQVDWRDHFLYCANAPL 530
Query: 503 CFQHYTSTE-TCFSAFKAPLEPTTALGGFSGNNYSEASAFIITYPVNNALTKVGDEN-GK 560
F+ T+ +C + + AP+ P A+GG+ G +YSEA A I+T+ +NN GD +
Sbjct: 531 TFKDGTALALSCMADYGAPVFPFLAVGGYKGKDYSEAEALIMTFSLNN--YPAGDPRLAQ 588
Query: 561 AIAWEKAFIQ 570
A WE+AF++
Sbjct: 589 AQLWEEAFLE 598
>E2C5L5_HARSA (tr|E2C5L5) Niemann-Pick C1 protein OS=Harpegnathos saltator
GN=EAI_16474 PE=4 SV=1
Length = 1333
Score = 167 bits (424), Expect = 9e-39, Method: Compositional matrix adjust.
Identities = 159/614 (25%), Positives = 251/614 (40%), Gaps = 127/614 (20%)
Query: 35 SIHSNEYCAMYDICGQRSDGKVLNCPYPSPSVKPHDLLSAKIQSL----CPTITG----- 85
S ++C Y C K NCPY P+ LL + Q L CP +
Sbjct: 41 SADDGDHCVWYGECYMDFHKK--NCPYDGPA----KLLEPEGQKLLAKHCPHLLVDNGKG 94
Query: 86 -NVCCTEEQLQ--------AVPILVGCPACLRNFLNLFCELSCSPNQSLFINVTSISQVD 136
N CC +QL A L CP+CL N + C+ +C+ NQS F+N+T ++ +
Sbjct: 95 INTCCDVKQLVTLDSNINIASNFLKRCPSCLDNLVKHICDFTCAVNQSKFMNITEKARAN 154
Query: 137 GNMTVDGIDLYVTETFGEGLYSACKDVKFGTMNTRAIDFV----GAGANNYKEWFAFLGQ 192
++G+D+Y+T + EG +++C V + A+D + GA +WF F+G
Sbjct: 155 DVEYINGVDVYITNKYLEGTFNSCNKVSLPSTGLLALDLMCGDWGASRCTALKWFHFMGD 214
Query: 193 KVPPGFPGSPYSIDFKTTILDSSPMELMNASVYSCNDTSLGXXXXXXXXXXXXXXXXXXX 252
+ P+ I + T + E ++ V CN
Sbjct: 215 AANNAY--VPFQITYVNTDGPVNSFEPLDPQVTPCNKA---------------------- 250
Query: 253 XXXXXXXIKMGSLKVRCVD------LSLAVLYIVLVFVLFGWIXXXXXXXXXXXGSSAEP 306
+ + CVD + + F +FG+ +
Sbjct: 251 -------LNKNTPACSCVDCEQSCPVPPPAPPLPQPFSIFGYDGYEVTMTIIFVCGTCLF 303
Query: 307 LLVSEGRSFTNLPKDGEVLVID-PQRQNEVQYSFIQEW-------LSNFYRAYGRWAARR 358
LL+ F+ + G + D P +E + +FI++ L F+ +G A R
Sbjct: 304 LLLV--MCFSQRKRIGVISTDDIPSGFDEERSTFIEKLGAGTDKLLQEFFCKWGTVCASR 361
Query: 359 PTIVLCSSLAIVILLCFGLLRFNVETRPEKLWVGPESKAAEEKEFFDSHLAPFYRIEQLI 418
P +L +++ L G+ V T P +LW P S++ E+E+FD H PFYR EQ+I
Sbjct: 362 PWAILFLGFLLIVGLGHGIKYIKVTTDPVELWASPHSRSRVEREYFDQHFEPFYRNEQII 421
Query: 419 IAT--LPESEHGKPPS------IVTDDNIELLFEIQEKVDEIRA--NYSGLLVSLSDICL 468
I + LP+ H + D ++ ++E+QE + I NY +L+DIC
Sbjct: 422 ITSVGLPDIVHNTTNGPIVFGPVFNDTFLKTIYELQEGIKNIVTPNNY-----TLADICF 476
Query: 469 KPLG---------EDCATQSILQYFQMDPDNFD----------NYGGVEHAEYCFQHYTS 509
PL C QSI Y+Q F+ NY ++H C Q+
Sbjct: 477 APLSGPFTGPTTISQCTIQSIWGYWQDSLSTFEEEHEEGNFTVNY--LDHFRACSQN-AY 533
Query: 510 TETCFSAFKAPLEPTTALGGF--SGNN-----YSEASAFIITYPVNNALTKVGDENGK-- 560
C + + P+EP A+GGF G + Y +A+A IIT+ VNN K GK
Sbjct: 534 NPACLALYGGPVEPAIAVGGFLAPGQDLYNPPYEKATAIIITFLVNNYHNK-----GKLL 588
Query: 561 -AIAWEKAFIQLAK 573
A+ WE++FIQ K
Sbjct: 589 PAMEWEESFIQFMK 602