Result of FASTA (omim) for pF1KE3008
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3008, 89 aa
  1>>>pF1KE3008 89 - 89 aa - 89 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.4751+/-0.000304; mu= 12.9491+/- 0.019
 mean_var=49.0983+/- 9.892, 0's: 0 Z-trim(116.2): 49  B-trim: 8 in 1/53
 Lambda= 0.183038
 statistics sampled from 27176 (27225) to 27176 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.319), width:  16
 Scan time:  3.400

The best scores are:                                      opt bits E(85289)
NP_690865 (OMIM: 615700) pyrin domain-containing p (  89)  552 152.5 8.5e-38
NP_660183 (OMIM: 606838) apoptosis-associated spec ( 176)  344 97.7 5.1e-21
NP_037390 (OMIM: 606838) apoptosis-associated spec ( 195)  344 97.8 5.5e-21
NP_001185465 (OMIM: 134610,249100,608107) pyrin is ( 445)  164 50.4 2.2e-06
XP_016878725 (OMIM: 134610,249100,608107) PREDICTE ( 780)  164 50.6 3.5e-06
NP_000234 (OMIM: 134610,249100,608107) pyrin isofo ( 781)  164 50.6 3.5e-06
XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR  ( 655)  143 45.0 0.00014
NP_789791 (OMIM: 609662) NACHT, LRR and PYD domain ( 655)  143 45.0 0.00014
XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR  ( 703)  140 44.2 0.00026
XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR  ( 771)  140 44.2 0.00028
NP_001263629 (OMIM: 609650) NACHT, LRR and PYD dom ( 891)  140 44.3 0.00032
NP_612202 (OMIM: 609650) NACHT, LRR and PYD domain ( 892)  140 44.3 0.00032
XP_011542357 (OMIM: 120100,191900,606416,607115) P ( 865)  130 41.6  0.0019
XP_011542355 (OMIM: 120100,191900,606416,607115) P ( 922)  130 41.6   0.002
XP_016855673 (OMIM: 120100,191900,606416,607115) P ( 922)  130 41.6   0.002
NP_899632 (OMIM: 120100,191900,606416,607115) NACH ( 922)  130 41.6   0.002
XP_016855672 (OMIM: 120100,191900,606416,607115) P ( 979)  130 41.7  0.0021
NP_001120934 (OMIM: 120100,191900,606416,607115) N ( 979)  130 41.7  0.0021
NP_001120933 (OMIM: 120100,191900,606416,607115) N ( 979)  130 41.7  0.0021
NP_001230062 (OMIM: 120100,191900,606416,607115) N (1034)  130 41.7  0.0022
XP_016855670 (OMIM: 120100,191900,606416,607115) P (1036)  130 41.7  0.0022
XP_016855671 (OMIM: 120100,191900,606416,607115) P (1036)  130 41.7  0.0022
NP_004886 (OMIM: 120100,191900,606416,607115) NACH (1036)  130 41.7  0.0022
NP_001073289 (OMIM: 120100,191900,606416,607115) N (1036)  130 41.7  0.0022
XP_011542350 (OMIM: 120100,191900,606416,607115) P (1036)  130 41.7  0.0022


>>NP_690865 (OMIM: 615700) pyrin domain-containing prote  (89 aa)
 initn: 552 init1: 552 opt: 552  Z-score: 799.5  bits: 152.5 E(85289): 8.5e-38
Smith-Waterman score: 552; 100.0% identity (100.0% similar) in 89 aa overlap (1-89:1-89)

               10        20        30        40        50        60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
               10        20        30        40        50        60

               70        80         
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA
       :::::::::::::::::::::::::::::
NP_690 YEDYAAELVVAVLRDMRMLEEAARLQRAA
               70        80         

>>NP_660183 (OMIM: 606838) apoptosis-associated speck-li  (176 aa)
 initn: 344 init1: 344 opt: 344  Z-score: 498.3  bits: 97.7 E(85289): 5.1e-21
Smith-Waterman score: 344; 64.8% identity (81.8% similar) in 88 aa overlap (1-88:1-88)

               10        20        30        40        50        60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
       ::  :.::: .::::: :::::::.:: .::::::. ::::::: ..: .:::::::. :
NP_660 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
               10        20        30        40        50        60

               70        80                                        
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA                               
        : :.:::.. ::::: . : :..:: :                                
NP_660 LETYGAELTANVLRDMGLQEMAGQLQAATHQGLHFIDQHRAALIARVTNVEWLLDALYGK
               70        80        90       100       110       120

>>NP_037390 (OMIM: 606838) apoptosis-associated speck-li  (195 aa)
 initn: 344 init1: 344 opt: 344  Z-score: 497.7  bits: 97.8 E(85289): 5.5e-21
Smith-Waterman score: 344; 64.8% identity (81.8% similar) in 88 aa overlap (1-88:1-88)

               10        20        30        40        50        60
pF1KE3 MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVASY
       ::  :.::: .::::: :::::::.:: .::::::. ::::::: ..: .:::::::. :
NP_037 MGRARDAILDALENLTAEELKKFKLKLLSVPLREGYGRIPRGALLSMDALDLTDKLVSFY
               10        20        30        40        50        60

               70        80                                        
pF1KE3 YEDYAAELVVAVLRDMRMLEEAARLQRAA                               
        : :.:::.. ::::: . : :..:: :                                
NP_037 LETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRA
               70        80        90       100       110       120

>>NP_001185465 (OMIM: 134610,249100,608107) pyrin isofor  (445 aa)
 initn: 164 init1: 164 opt: 164  Z-score: 235.5  bits: 50.4 E(85289): 2.2e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)

                10        20        30        40        50         
pF1KE3  MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
          :  . .:..::.:.: ...:::.:: .. ...   ::::. . .   : ..  ::. 
NP_001 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
               10        20        30        40        50        60

      60        70        80                                       
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA                              
       : :.::..:.. ::: . .   : .:.:::                              
NP_001 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQGRPPDTAASPRCHAQEGDPVDGTCVRDS
               70        80        90       100       110       120

>>XP_016878725 (OMIM: 134610,249100,608107) PREDICTED: p  (780 aa)
 initn: 164 init1: 164 opt: 164  Z-score: 231.9  bits: 50.6 E(85289): 3.5e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)

                10        20        30        40        50         
pF1KE3  MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
          :  . .:..::.:.: ...:::.:: .. ...   ::::. . .   : ..  ::. 
XP_016 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
               10        20        30        40        50        60

      60        70        80                                       
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA                              
       : :.::..:.. ::: . .   : .:.:::                              
XP_016 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
               70        80        90       100       110       120

>>NP_000234 (OMIM: 134610,249100,608107) pyrin isoform 1  (781 aa)
 initn: 164 init1: 164 opt: 164  Z-score: 231.9  bits: 50.6 E(85289): 3.5e-06
Smith-Waterman score: 164; 35.6% identity (70.1% similar) in 87 aa overlap (3-89:4-90)

                10        20        30        40        50         
pF1KE3  MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDKLVAS
          :  . .:..::.:.: ...:::.:: .. ...   ::::. . .   : ..  ::. 
NP_000 MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTY
               10        20        30        40        50        60

      60        70        80                                       
pF1KE3 YYEDYAAELVVAVLRDMRMLEEAARLQRAA                              
       : :.::..:.. ::: . .   : .:.:::                              
NP_000 YGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKT
               70        80        90       100       110       120

>>XP_011518345 (OMIM: 609662) PREDICTED: NACHT, LRR and   (655 aa)
 initn: 142 init1: 142 opt: 143  Z-score: 203.1  bits: 45.0 E(85289): 0.00014
Smith-Waterman score: 143; 37.0% identity (65.4% similar) in 81 aa overlap (5-85:10-90)

                    10        20        30        40        50     
pF1KE3      MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDK
                :::.: .: .:  ...::.:. :  . : ::   . :: :  :  :::.. 
XP_011 MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAEL
               10        20        30        40        50        60

          60        70        80                                   
pF1KE3 LVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA                          
       :...: :  :...:.  :. : .:: . .:                              
XP_011 LISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGR
               70        80        90       100       110       120

>>NP_789791 (OMIM: 609662) NACHT, LRR and PYD domains-co  (655 aa)
 initn: 142 init1: 142 opt: 143  Z-score: 203.1  bits: 45.0 E(85289): 0.00014
Smith-Waterman score: 143; 37.0% identity (65.4% similar) in 81 aa overlap (5-85:10-90)

                    10        20        30        40        50     
pF1KE3      MGTKREAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTDK
                :::.: .: .:  ...::.:. :  . : ::   . :: :  :  :::.. 
NP_789 MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAEL
               10        20        30        40        50        60

          60        70        80                                   
pF1KE3 LVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA                          
       :...: :  :...:.  :. : .:: . .:                              
NP_789 LISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGR
               70        80        90       100       110       120

>>XP_011518233 (OMIM: 609650) PREDICTED: NACHT, LRR and   (703 aa)
 initn: 143 init1:  79 opt: 140  Z-score: 198.4  bits: 44.2 E(85289): 0.00026
Smith-Waterman score: 140; 36.8% identity (64.4% similar) in 87 aa overlap (1-86:15-98)

                             10        20        30         40     
pF1KE3               MGTKREAILKVLENLTPEELKKFKMKLGTV-PLREGFERIPRGALG
                     ... :: .: .::.:. :.::.:. ::  : :  .: . :: : : 
XP_011 MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGP--DG-RSIPWGRLE
               10        20        30        40           50       

          50        60        70        80                         
pF1KE3 QLDIVDLTDKLVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA                
       . : :::...:.  :  . : :..  .:.     . ::.::                   
XP_011 RADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSE
        60        70        80        90       100       110       

XP_011 YKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRS
       120       130       140       150       160       170       

>>XP_016872741 (OMIM: 609650) PREDICTED: NACHT, LRR and   (771 aa)
 initn: 143 init1:  79 opt: 140  Z-score: 197.8  bits: 44.2 E(85289): 0.00028
Smith-Waterman score: 140; 36.8% identity (64.4% similar) in 87 aa overlap (1-86:15-98)

                             10        20        30         40     
pF1KE3               MGTKREAILKVLENLTPEELKKFKMKLGTV-PLREGFERIPRGALG
                     ... :: .: .::.:. :.::.:. ::  : :  .: . :: : : 
XP_016 MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGP--DG-RSIPWGRLE
               10        20        30        40           50       

          50        60        70        80                         
pF1KE3 QLDIVDLTDKLVASYYEDYAAELVVAVLRDMRMLEEAARLQRAA                
       . : :::...:.  :  . : :..  .:.     . ::.::                   
XP_016 RADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSE
        60        70        80        90       100       110       

XP_016 YKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRS
       120       130       140       150       160       170       




89 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Mon Nov  7 20:46:38 2016 done: Mon Nov  7 20:46:39 2016
 Total Scan time:  3.400 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]
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