Result of FASTA (omim) for
pF1KB5943
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5943, 508 aa
1>>>pF1KB5943 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1025+/-0.000336; mu= 19.5005+/- 0.021
mean_var=68.3687+/-13.235, 0's: 0 Z-trim(115.0): 59 B-trim: 191 in 1/50
Lambda= 0.155112
statistics sampled from 25176 (25235) to 25176 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.296), width: 16
Scan time: 10.360
The best scores are: opt bits E(85289)
NP_001017520 (OMIM: 187410) DNA nucleotidylexotran ( 508) 3362 761.4 0
NP_004079 (OMIM: 187410) DNA nucleotidylexotransfe ( 509) 3350 758.8 8.6e-219
XP_011513581 (OMIM: 606344) PREDICTED: DNA-directe ( 499) 1267 292.6 1.8e-78
NP_037416 (OMIM: 606344) DNA-directed DNA/RNA poly ( 494) 1183 273.8 8e-73
XP_011513577 (OMIM: 606344) PREDICTED: DNA-directe ( 593) 1153 267.2 9.7e-71
XP_006715755 (OMIM: 606344) PREDICTED: DNA-directe ( 588) 1069 248.4 4.4e-65
XP_006715759 (OMIM: 606344) PREDICTED: DNA-directe ( 498) 705 166.8 1.3e-40
NP_001271260 (OMIM: 606344) DNA-directed DNA/RNA p ( 457) 583 139.5 2e-32
XP_011513588 (OMIM: 606344) PREDICTED: DNA-directe ( 265) 524 126.2 1.2e-28
XP_016867494 (OMIM: 606344) PREDICTED: DNA-directe ( 286) 499 120.6 6.2e-27
XP_016867493 (OMIM: 606344) PREDICTED: DNA-directe ( 289) 498 120.4 7.3e-27
XP_016867488 (OMIM: 606344) PREDICTED: DNA-directe ( 513) 498 120.5 1.2e-26
XP_016867487 (OMIM: 606344) PREDICTED: DNA-directe ( 531) 498 120.5 1.2e-26
XP_011513580 (OMIM: 606344) PREDICTED: DNA-directe ( 543) 498 120.6 1.2e-26
XP_011513589 (OMIM: 606344) PREDICTED: DNA-directe ( 247) 491 118.7 1.9e-26
XP_011513584 (OMIM: 606344) PREDICTED: DNA-directe ( 360) 491 118.9 2.6e-26
XP_011513587 (OMIM: 606344) PREDICTED: DNA-directe ( 324) 486 117.7 5.2e-26
XP_016867491 (OMIM: 606344) PREDICTED: DNA-directe ( 324) 486 117.7 5.2e-26
XP_016867492 (OMIM: 606344) PREDICTED: DNA-directe ( 324) 486 117.7 5.2e-26
XP_006715761 (OMIM: 606344) PREDICTED: DNA-directe ( 361) 486 117.7 5.6e-26
XP_016867489 (OMIM: 606344) PREDICTED: DNA-directe ( 449) 459 111.8 4.4e-24
NP_001271259 (OMIM: 606344) DNA-directed DNA/RNA p ( 508) 414 101.7 5.2e-21
XP_016867490 (OMIM: 606344) PREDICTED: DNA-directe ( 419) 382 94.5 6.4e-19
XP_005249768 (OMIM: 606344) PREDICTED: DNA-directe ( 448) 345 86.3 2.1e-16
XP_016871580 (OMIM: 606343) PREDICTED: DNA polymer ( 406) 344 86.0 2.3e-16
NP_037406 (OMIM: 606343) DNA polymerase lambda iso ( 575) 344 86.1 3e-16
NP_001167555 (OMIM: 606343) DNA polymerase lambda ( 575) 344 86.1 3e-16
XP_011537953 (OMIM: 606343) PREDICTED: DNA polymer ( 575) 344 86.1 3e-16
XP_011537962 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 333 83.5 1.3e-15
XP_016871578 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 333 83.5 1.3e-15
XP_011537961 (OMIM: 606343) PREDICTED: DNA polymer ( 413) 333 83.5 1.3e-15
XP_011537959 (OMIM: 606343) PREDICTED: DNA polymer ( 494) 333 83.6 1.5e-15
XP_011537952 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 333 83.6 1.7e-15
XP_011537954 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 333 83.6 1.7e-15
XP_011537955 (OMIM: 606343) PREDICTED: DNA polymer ( 582) 333 83.6 1.7e-15
XP_006717840 (OMIM: 606343) PREDICTED: DNA polymer ( 300) 293 74.5 4.9e-13
NP_001295311 (OMIM: 606343) DNA polymerase lambda ( 300) 293 74.5 4.9e-13
XP_006717839 (OMIM: 606343) PREDICTED: DNA polymer ( 314) 289 73.6 9.4e-13
XP_006717838 (OMIM: 606343) PREDICTED: DNA polymer ( 314) 289 73.6 9.4e-13
XP_016871575 (OMIM: 606343) PREDICTED: DNA polymer ( 469) 289 73.7 1.3e-12
NP_001167556 (OMIM: 606343) DNA polymerase lambda ( 483) 289 73.7 1.3e-12
XP_011537957 (OMIM: 606343) PREDICTED: DNA polymer ( 483) 289 73.7 1.3e-12
XP_011537968 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 282 72.0 2.7e-12
XP_011537967 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 282 72.0 2.7e-12
XP_011537966 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 282 72.0 2.7e-12
XP_016871582 (OMIM: 606343) PREDICTED: DNA polymer ( 307) 282 72.0 2.7e-12
NP_002681 (OMIM: 174760) DNA polymerase beta [Homo ( 335) 281 71.8 3.4e-12
XP_011537964 (OMIM: 606343) PREDICTED: DNA polymer ( 321) 278 71.2 5.3e-12
XP_011537965 (OMIM: 606343) PREDICTED: DNA polymer ( 321) 278 71.2 5.3e-12
XP_011537958 (OMIM: 606343) PREDICTED: DNA polymer ( 476) 278 71.3 7.2e-12
>>NP_001017520 (OMIM: 187410) DNA nucleotidylexotransfer (508 aa)
initn: 3362 init1: 3362 opt: 3362 Z-score: 4063.5 bits: 761.4 E(85289): 0
Smith-Waterman score: 3362; 99.8% identity (99.8% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KB5 MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIGAGKPVEMT
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRFERDLRRYATHERKMILDNHALYDKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRFERDLRRYATHERKMILDNHALYDKTK
430 440 450 460 470 480
490 500
pF1KB5 RIFLKAESEEEIFAHLGLDYIEPWERNA
::::::::::::::::::::::::::::
NP_001 RIFLKAESEEEIFAHLGLDYIEPWERNA
490 500
>>NP_004079 (OMIM: 187410) DNA nucleotidylexotransferase (509 aa)
initn: 2994 init1: 2994 opt: 3350 Z-score: 4049.0 bits: 758.8 E(85289): 8.6e-219
Smith-Waterman score: 3350; 99.6% identity (99.6% similar) in 509 aa overlap (1-508:1-509)
10 20 30 40 50 60
pF1KB5 MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDPPRASHLSPRKKRPRQTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELARRKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIGAGKPVEMT
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_004 FRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVSSQPELLDVSWLIECIRAGKPVEMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFDILAENCE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGESSEVKAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGFLYYEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGSTEDEEQL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQKVMNLWEKKGLLLYYDLVESTFEKLRLPSRKVDALDHFQKCFLIFKLPRQRVDSDQSS
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHERKMILDNHALYDKT
::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_004 WQEGKTWKAIRVDLVLCPYERRAFALLGWTGSRQFERDLRRYATHERKMILDNHALYDKT
430 440 450 460 470 480
480 490 500
pF1KB5 KRIFLKAESEEEIFAHLGLDYIEPWERNA
:::::::::::::::::::::::::::::
NP_004 KRIFLKAESEEEIFAHLGLDYIEPWERNA
490 500
>>XP_011513581 (OMIM: 606344) PREDICTED: DNA-directed DN (499 aa)
initn: 1046 init1: 326 opt: 1267 Z-score: 1529.9 bits: 292.6 E(85289): 1.8e-78
Smith-Waterman score: 1267; 40.9% identity (69.2% similar) in 513 aa overlap (11-508:3-499)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_011 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_011 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFT----
:.:: . .:.: : :: : : .. . ::::: : :.. : ..
XP_011 GQPVPVECRHRLEV---------AGPRKGP-LSPAWMPAYACQRPTPLTHHNTGLSGPSL
120 130 140 150 160
170 180 190 200 210 220
pF1KB5 -DAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEI
.:..:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:.
XP_011 QEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQEL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 IEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRM
.: : ::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..
XP_011 LEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB5 QKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLI
::::. ...:: . : :....:.. .:.::: :: : ::.:::::::: .::::::::
XP_011 QKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLI
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 TSPGSTEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLI
: : . : :: .:: . .::.::.. .: :. :.: . . .: :.. : :
XP_011 THPKEGQ-EAGLLPRVMCRLQDQGLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCI
350 360 370 380 390
410 420 430 440 450 460
pF1KB5 FKLPRQRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHE
:.::. . .: . .:::.:::::. : . :::::::::. :.:.:::.. .:
XP_011 FRLPQPPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKE
400 410 420 430 440 450
470 480 490 500
pF1KB5 RKMILDNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
. . :..:.:.: .. :..: :::.:: ::::.:. : .:::
XP_011 KGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
460 470 480 490
>>NP_037416 (OMIM: 606344) DNA-directed DNA/RNA polymera (494 aa)
initn: 1013 init1: 375 opt: 1183 Z-score: 1428.4 bits: 273.8 E(85289): 8e-73
Smith-Waterman score: 1287; 41.3% identity (69.9% similar) in 508 aa overlap (11-508:3-494)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
NP_037 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
NP_037 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFD
:.:: . .:.: : :: : : .. . ::::: : :.. : ...:..
NP_037 GQPVPVECRHRLEV---------AGPRKGP-LSPAWMPAYACQRPTPLTHHNTGLSEALE
120 130 140 150 160
180 190 200 210 220 230
pF1KB5 ILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGE
:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:..: :
NP_037 ILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 SSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGF
::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..::::.
NP_037 CEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQQKAGL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 LYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGS
...:: . : :....:.. .:.::: :: : ::.:::::::: .::::::::: :
NP_037 QHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKE
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 TEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLIFKLPR
. : :: .:: . .::.::.. .: :. :.: . . .: :.. : ::.::.
NP_037 GQ-EAGLLPRVMCRLQDQGLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCIFRLPQ
350 360 370 380 390
420 430 440 450 460 470
pF1KB5 QRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHERKMIL
. .: . .:::.:::::. : . :::::::::. :.:.:::.. .:. . :
NP_037 PPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWL
400 410 420 430 440 450
480 490 500
pF1KB5 DNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
..:.:.: .. :..: :::.:: ::::.:. : .:::
NP_037 NSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
460 470 480 490
>>XP_011513577 (OMIM: 606344) PREDICTED: DNA-directed DN (593 aa)
initn: 1034 init1: 326 opt: 1153 Z-score: 1391.0 bits: 267.2 E(85289): 9.7e-71
Smith-Waterman score: 1153; 39.8% identity (68.7% similar) in 482 aa overlap (11-477:3-468)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_011 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_011 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFT----
:.:: . .:.: : . :. :.. . ::::: : :.. : ..
XP_011 GQPVPVECRHRLEV----------AGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSGPSL
120 130 140 150 160
170 180 190 200 210 220
pF1KB5 -DAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEI
.:..:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:.
XP_011 QEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQEL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 IEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRM
.: : ::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..
XP_011 LEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB5 QKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLI
::::. ...:: . : :....:.. .:.::: :: : ::.:::::::: .::::::::
XP_011 QKAGLQHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLI
290 300 310 320 330 340
350 360 370 380 390 400
pF1KB5 TSPGSTEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLI
: : . : :: .:: . .::.::.. .: :. :.: . . .: :.. : :
XP_011 THPKEGQ-EAGLLPRVMCRLQDQGLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCI
350 360 370 380 390
410 420 430 440 450 460
pF1KB5 FKLPRQRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHE
:.::. . .: . .:::.:::::. : . :::::::::. :.:.:::.. .:
XP_011 FRLPQPPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKE
400 410 420 430 440 450
470 480 490 500
pF1KB5 RKMILDNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
. . :..:.:.:
XP_011 KGLWLNSHGLFDPEQGSSSGKTPRSRKSCFCCRRHFSKRLQRKTSSDTWALSTFLQSRET
460 470 480 490 500 510
>>XP_006715755 (OMIM: 606344) PREDICTED: DNA-directed DN (588 aa)
initn: 1001 init1: 375 opt: 1069 Z-score: 1289.4 bits: 248.4 E(85289): 4.4e-65
Smith-Waterman score: 1173; 40.3% identity (69.4% similar) in 477 aa overlap (11-477:3-463)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_006 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_006 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFD
:.:: . .:.: : . :. :.. . ::::: : :.. : ...:..
XP_006 GQPVPVECRHRLEV----------AGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALE
120 130 140 150 160
180 190 200 210 220 230
pF1KB5 ILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGE
:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:..: :
XP_006 ILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 SSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGF
::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..::::.
XP_006 CEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQQKAGL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 LYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGS
...:: . : :....:.. .:.::: :: : ::.:::::::: .::::::::: :
XP_006 QHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKE
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 TEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLIFKLPR
. : :: .:: . .::.::.. .: :. :.: . . .: :.. : ::.::.
XP_006 GQ-EAGLLPRVMCRLQDQGLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCIFRLPQ
350 360 370 380 390
420 430 440 450 460 470
pF1KB5 QRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHERKMIL
. .: . .:::.:::::. : . :::::::::. :.:.:::.. .:. . :
XP_006 PPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWL
400 410 420 430 440 450
480 490 500
pF1KB5 DNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
..:.:.:
XP_006 NSHGLFDPEQGSSSGKTPRSRKSCFCCRRHFSKRLQRKTSSDTWALSTFLQSRETPEPAC
460 470 480 490 500 510
>>XP_006715759 (OMIM: 606344) PREDICTED: DNA-directed DN (498 aa)
initn: 731 init1: 244 opt: 705 Z-score: 850.2 bits: 166.8 E(85289): 1.3e-40
Smith-Waterman score: 800; 34.0% identity (57.2% similar) in 477 aa overlap (11-477:3-373)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_006 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_006 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFD
:.:: :. :..:
XP_006 GQPV--------------------------PVE--------CRHR---------------
120
180 190 200 210 220 230
pF1KB5 ILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGE
.::..: :
XP_006 ---------------------------------------------------LEELLEHGV
130
240 250 260 270 280 290
pF1KB5 SSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGF
::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..::::.
XP_006 CEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQQKAGL
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB5 LYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGS
...:: . : :....:.. .:.::: :: : ::.:::::::: .::::::::: :
XP_006 QHHQDLSTPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITHPKE
200 210 220 230 240 250
360 370 380 390 400 410
pF1KB5 TEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLIFKLPR
. : :: .:: . .::.::.. .: :. :.: . . .: :.. : ::.::.
XP_006 GQ-EAGLLPRVMCRLQDQGLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCIFRLPQ
260 270 280 290 300
420 430 440 450 460 470
pF1KB5 QRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHERKMIL
. .: . .:::.:::::. : . :::::::::. :.:.:::.. .:. . :
XP_006 PPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWL
310 320 330 340 350 360
480 490 500
pF1KB5 DNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
..:.:.:
XP_006 NSHGLFDPEQGSSSGKTPRSRKSCFCCRRHFSKRLQRKTSSDTWALSTFLQSRETPEPAC
370 380 390 400 410 420
>>NP_001271260 (OMIM: 606344) DNA-directed DNA/RNA polym (457 aa)
initn: 783 init1: 375 opt: 583 Z-score: 703.2 bits: 139.5 E(85289): 2e-32
Smith-Waterman score: 979; 36.2% identity (62.4% similar) in 508 aa overlap (11-508:3-457)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
NP_001 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
NP_001 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFTDAFD
:.:: . .:.: : :: : : .. . ::::: : :.. : ...:..
NP_001 GQPVPVECRHRLEV---------AGPRKGP-LSPAWMPAYACQRPTPLTHHNTGLSEALE
120 130 140 150 160
180 190 200 210 220 230
pF1KB5 ILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEIIEDGE
:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:..: :
NP_001 ILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGV
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 SSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRMQKAGF
::. : .::::..::::..::::.::...:.: :.:::. .: .. :.:..:::
NP_001 CEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYREGLRTLDDLR-EQPQKLTQQQKA--
230 240 250 260 270
300 310 320 330 340 350
pF1KB5 LYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLITSPGS
: . :: : : :: : . : . :
NP_001 --------------APPGPEHPSPAVRCRCPAA-----GG---GGSCGAGPAW-----GH
280 290 300 310
360 370 380 390 400 410
pF1KB5 TEDEEQLLQKVMNLWEKKGLLLYYDLVESTFEKLRLPSR--KVDALDHFQKCFLIFKLPR
. ...: : ::.::.. .: :. :.: . . .: :.. : ::.::.
NP_001 RHADRRLPQ---------GLILYHQHQHSCCES---PTRLAQQSHMDAFERSFCIFRLPQ
320 330 340 350
420 430 440 450 460 470
pF1KB5 QRVDSDQSSWQEGKTWKAIRVDLVLCPYERRAFALLGWTGSR-FERDLRRYATHERKMIL
. .: . .:::.:::::. : . :::::::::. :.:.:::.. .:. . :
NP_001 PPGAAVGGSTRPCPSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWL
360 370 380 390 400 410
480 490 500
pF1KB5 DNHALYDKTKRIFLKAESEEEIFAHLGLDYIEPWERNA
..:.:.: .. :..: :::.:: ::::.:. : .:::
NP_001 NSHGLFDPEQKTFFQAASEEDIFRHLGLEYLPPEQRNA
420 430 440 450
>>XP_011513588 (OMIM: 606344) PREDICTED: DNA-directed DN (265 aa)
initn: 462 init1: 201 opt: 524 Z-score: 635.2 bits: 126.2 E(85289): 1.2e-28
Smith-Waterman score: 524; 34.7% identity (63.4% similar) in 268 aa overlap (11-266:3-258)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_011 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_011 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFT----
:.:: . .:.: : . :. :.. . ::::: : :.. : ..
XP_011 GQPVPVECRHRLEV----------AGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSGPSL
120 130 140 150 160
170 180 190 200 210 220
pF1KB5 -DAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEI
.:..:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:.
XP_011 QEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQEL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 IEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRM
.: : ::. : .::::..:. .: :. : . :
XP_011 LEHGVCEEVERVRRSERYQTMKV-ASGDGACLVHGAPWATPSRSG
230 240 250 260
290 300 310 320 330 340
pF1KB5 QKAGFLYYEDLVSCVTRAEAEAVSVLVKEAVWAFLPDAFVTMTGGFRRGKKMGHDVDFLI
>>XP_016867494 (OMIM: 606344) PREDICTED: DNA-directed DN (286 aa)
initn: 439 init1: 178 opt: 499 Z-score: 604.5 bits: 120.6 E(85289): 6.2e-27
Smith-Waterman score: 499; 35.3% identity (63.5% similar) in 249 aa overlap (11-247:3-240)
10 20 30 40 50
pF1KB5 MDPPRASHLSPRKKRPR---QTGALMASSPQDIKFQDLVVFILEKKMGTTRRAFLMELAR
:...: : .: .:.: . .: ......: .:: .::::: :::
XP_016 MLPKRRRARVGSPSGDAASSTPPSTRFPGVAIYLVEPRMGRSRRAFLTGLAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 RKGFRVENELSDSVTHIVAENNSGSDVLEWLQAQKVQVS----SQPELLDVSWLIECIGA
::::: . :. .::.: :..:. ... : : ... .. . : :::.::: : .::
XP_016 SKGFRVLDACSSEATHVVMEETSAEEAVSW-QERRMAAAPPGCTPPALLDISWLTESLGA
60 70 80 90 100 110
120 130 140 150 160
pF1KB5 GKPVEMTGKHQLVVRRDYSDSTNPGPPKTPPIAVQKISQYACQRRTTLNNCNQIFT----
:.:: . .:.: : :: : : .. . ::::: : :.. : ..
XP_016 GQPVPVECRHRLEV---------AGPRKGP-LSPAWMPAYACQRPTPLTHHNTGLSGPSL
120 130 140 150 160
170 180 190 200 210 220
pF1KB5 -DAFDILAENCEFRENEDSCVTFMRAASVLKSLPFTIISMKDTEGIPCLGSKVKGIIEEI
.:..:::: :. .: .:: :::::::.:: . .... .:.: .: . . ...:.
XP_016 QEALEILAEAAGFEGSEGRLLTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQEL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB5 IEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRTLSKVRSDKSLKFTRM
.: : ::. : .:: .
XP_016 LEHGVCEEVERVRRSERLEYSGAITAHGSLDFLGSNHPPTSVSGVAGTTGMCHHTSSSPR
230 240 250 260 270 280
508 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 04:45:43 2016 done: Mon Nov 7 04:45:44 2016
Total Scan time: 10.360 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]