Result of FASTA (omim) for pF1KB9123
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9123, 505 aa
  1>>>pF1KB9123 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 15.6243+/-0.000534; mu= -24.4549+/- 0.034
 mean_var=1000.7394+/-205.930, 0's: 0 Z-trim(125.8): 150  B-trim: 0 in 0/62
 Lambda= 0.040543
 statistics sampled from 50082 (50287) to 50082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.59), width:  16
 Scan time: 12.720

The best scores are:                                      opt bits E(85289)
NP_003932 (OMIM: 605056) neural Wiskott-Aldrich sy ( 505) 3600 225.9 2.2e-58
NP_000368 (OMIM: 300299,300392,313900) wiskott-Ald ( 502)  863 65.8 3.4e-10
XP_016885275 (OMIM: 300299,300392,313900) PREDICTE ( 590)  863 65.9 3.8e-10
XP_011542279 (OMIM: 300299,300392,313900) PREDICTE ( 450)  724 57.6   9e-08
NP_008921 (OMIM: 605875) wiskott-Aldrich syndrome  ( 498)  489 43.9  0.0013
XP_016857330 (OMIM: 606373,616193) PREDICTED: form (1102)  498 44.8  0.0015
XP_016857329 (OMIM: 606373,616193) PREDICTED: form (1102)  498 44.8  0.0015
XP_016857328 (OMIM: 606373,616193) PREDICTED: form (1159)  498 44.9  0.0016
XP_011542539 (OMIM: 606373,616193) PREDICTED: form (1360)  498 44.9  0.0017
XP_016857327 (OMIM: 606373,616193) PREDICTED: form (1384)  498 45.0  0.0017
XP_016857326 (OMIM: 606373,616193) PREDICTED: form (1417)  498 45.0  0.0018
NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 (1722)  498 45.1   0.002
NP_001292353 (OMIM: 606373,616193) formin-2 isofor (1726)  498 45.1   0.002


>>NP_003932 (OMIM: 605056) neural Wiskott-Aldrich syndro  (505 aa)
 initn: 3600 init1: 3600 opt: 3600  Z-score: 1169.1  bits: 225.9 E(85289): 2.2e-58
Smith-Waterman score: 3600; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)

               10        20        30        40        50        60
pF1KB9 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK
              430       440       450       460       470       480

              490       500     
pF1KB9 AIHSSDEDEDEDDEEDFEDDDEWED
       :::::::::::::::::::::::::
NP_003 AIHSSDEDEDEDDEEDFEDDDEWED
              490       500     

>>NP_000368 (OMIM: 300299,300392,313900) wiskott-Aldrich  (502 aa)
 initn: 1526 init1: 606 opt: 863  Z-score: 303.9  bits: 65.8 E(85289): 3.4e-10
Smith-Waterman score: 1574; 48.7% identity (66.8% similar) in 536 aa overlap (11-505:16-502)

                    10        20        30        40        50     
pF1KB9      MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
                      :    :. : ::  .::. :: .::.::.:...:::::: :    
NP_000 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
          :.:.  :..:.::::::.:::.:.. .. :.::::::::...::..:  .:::::::
NP_000 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
               70        80        90       100       110       120

           120       130       140        150                      
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
        ::..::::.:.::. ::  : . . .: ::.:  ::.                      
NP_000 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
              130       140       150       160       170       180

                      160       170       180       190       200  
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
              :: :: .: .:::::.::.::..:. :  . . : . .:..::   :...:::
NP_000 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKAD
              190       200       210       220       230          

            210       220       230       240       250       260  
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
       ::.::.:.:..::::::..:::.:::::.:..::.  ::::::: : ::::.::::::  
NP_000 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
       240       250       260       270       280       290       

            270         280       290       300       310       320
pF1KB9 GGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA
       ::.:::..:.::: :  :::::::::   : ::  ...      .::..: ::   .: .
NP_000 GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLG
       300       310       320       330             340           

              330       340       350       360       370       380
pF1KB9 APPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP
         ::::  :      ::::.:  :::::  :... ::: ::::   : ::  ::::::::
NP_000 IAPPPPTPR-----GPPPPGRGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPP
      350            360       370        380        390       400 

                  390       400       410       420       430      
pF1KB9 PPP----GPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDA
       :::    :: :::  :.     ::  ::. :        :.               :: :
NP_000 PPPSSGNGPAPPPLPPA----LVP--AGGLAP-------GG---------------GRGA
             410           420                               430   

        440       450       460         470       480       490    
pF1KB9 LLDQIRQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDE
       :::::::::::...  . ::.   : : :  :.:::::.::::::.::::::: ::.  .
NP_000 LLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGD
           440       450       460       470       480       490   

          500     
pF1KB9 EDFEDDDEWED
       ::  .::::.:
NP_000 ED--EDDEWDD
             500  

>>XP_016885275 (OMIM: 300299,300392,313900) PREDICTED: w  (590 aa)
 initn: 1299 init1: 614 opt: 863  Z-score: 303.1  bits: 65.9 E(85289): 3.8e-10
Smith-Waterman score: 1497; 48.4% identity (66.5% similar) in 516 aa overlap (11-485:16-484)

                    10        20        30        40        50     
pF1KB9      MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
                      :    :. : ::  .::. :: .::.::.:...:::::: :    
XP_016 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
          :.:.  :..:.::::::.:::.:.. .. :.::::::::...::..:  .:::::::
XP_016 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
               70        80        90       100       110       120

           120       130       140        150                      
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
        ::..::::.:.::. ::  : . . .: ::.:  ::.                      
XP_016 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
              130       140       150       160       170       180

                      160       170       180       190       200  
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
              :: :: .: .:::::.::.::..:. :  . . : . .:..:   ::...:::
XP_016 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSG---KKKISKAD
              190       200       210       220          230       

            210       220       230       240       250       260  
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
       ::.::.:.:..::::::..:::.:::::.:..::.  ::::::: : ::::.::::::  
XP_016 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
       240       250       260       270       280       290       

            270         280       290       300       310       320
pF1KB9 GGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA
       ::.:::..:.::: :  :::::::::   : ::  ...      .::..: ::   .: .
XP_016 GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLG
       300       310       320       330             340           

              330       340       350       360       370       380
pF1KB9 APPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP
         ::::  :      ::::.:  :::::  :... ::: ::::   : ::  ::::::::
XP_016 IAPPPPTPRG-----PPPPGRGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPP
      350            360       370        380        390       400 

                  390       400       410       420       430      
pF1KB9 PPP----GPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDA
       :::    :: :::  :.     ::  ::. :        :.               :: :
XP_016 PPPSSGNGPAPPPLPPA----LVP--AGGLAP-------GG---------------GRGA
             410           420                               430   

        440       450       460         470       480       490    
pF1KB9 LLDQIRQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDE
       :::::::::::...  . ::.   : : :  :.:::::.::::::.:::::         
XP_016 LLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSGSRSVSQAG
           440       450       460       470       480       490   

          500                                                      
pF1KB9 EDFEDDDEWED                                                 
                                                                   
XP_016 VQWCNHGSVQPQPPRLKRSSRLSSQSSWDYRRVPPYLANFWCFFGSDELSLPSSHYSHVA
           500       510       520       530       540       550   

>>XP_011542279 (OMIM: 300299,300392,313900) PREDICTED: w  (450 aa)
 initn: 1515 init1: 484 opt: 724  Z-score: 260.5  bits: 57.6 E(85289): 9e-08
Smith-Waterman score: 1346; 45.2% identity (61.6% similar) in 531 aa overlap (11-505:16-450)

                    10        20        30        40        50     
pF1KB9      MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
                      :    :. : ::  .::. :: .::.::.:...:::::: :    
XP_011 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
               10        20        30        40        50        60

            60        70        80        90       100       110   
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
          :.:.  :..:.::::::.:::.:.. .. :.::::::::...::..:  .:::::::
XP_011 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
               70        80        90       100       110       120

           120       130       140        150                      
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
        ::..::::.:.::. ::  : . . .: ::.:  ::.                      
XP_011 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
              130       140       150       160       170       180

                      160       170       180       190       200  
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
              :: :: .: .:::::.::.::..:. :  . . : . .:..::   :...:::
XP_011 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKAD
              190       200       210       220       230          

            210       220       230       240       250       260  
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
       ::.::.:.:..::::::..:::.:::::.:..::.  ::::::: : ::::.::::::  
XP_011 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
       240       250       260       270       280       290       

            270       280       290       300       310        320 
pF1KB9 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAP-PPPPSRAPTAA
       ::.:::..:.:::.       ::::::::::          : ::..: ::::   : :.
XP_011 GGLEAVRQEMRRQG-------RGGPPPPPPP----------ATGRSGPLPPPP---PGAG
       300       310              320                 330          

             330       340       350       360       370       380 
pF1KB9 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP
        ::         .:::::                  :::::::  : :: :::: ::   
XP_011 GPP---------MPPPPP------------------PPPPPPSS-GNGP-APPPLPPALV
       340                                  350         360        

             390       400       410       420       430       440 
pF1KB9 PPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQI
       : :   : :                                          :: ::::::
XP_011 PAGGLAPGG------------------------------------------GRGALLDQI
      370                                                 380      

             450       460         470       480       490         
pF1KB9 RQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFED
       ::::::...  . ::.   : : :  :.:::::.::::::.::::::: ::.  .::  .
XP_011 RQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDED--E
        390       400       410       420       430       440      

     500     
pF1KB9 DDEWED
       ::::.:
XP_011 DDEWDD
          450

>>NP_008921 (OMIM: 605875) wiskott-Aldrich syndrome prot  (498 aa)
 initn: 342 init1: 342 opt: 489  Z-score: 185.8  bits: 43.9 E(85289): 0.0013
Smith-Waterman score: 561; 29.9% identity (52.2% similar) in 385 aa overlap (128-505:162-498)

       100       110       120       130       140       150       
pF1KB9 FVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNL
                                     .:. . . :.. ..... ....: ::  :.
NP_008 PLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNV
             140       150       160       170       180       190 

       160       170       180       190       200       210       
pF1KB9 PMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGW
           .  .. :    .. : .   . ..:::   ..    :.  . :. .  ...   ..
NP_008 NPRKIKTRKEEWEKMKM-GQE---FVESKEKLGTSGYPPTLVYQN-GSIGCVENVDASSY
             200        210          220       230        240      

       220        230       240       250       260         270    
pF1KB9 DPNTGFD-LNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTG-GVEAVK-NELRR
        :    :  .. .: .         :: .:     ..  :   .. : :. . : . .  
NP_008 PPPPQSDSASSPSPSF---------SEDNLPP-PPAEFSYPVDNQRGSGLAGPKRSSVVS
        250       260                 270       280       290      

          280       290          300       310       320       330 
pF1KB9 QAPPPPPPSRGGPPPPPP---PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS
        . ::: :  :.:: : :   ::    :::::    : :::::  .  .   ::::: ::
NP_008 PSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMI--GIPPPPPPVGFGSPGTPPPPSPPS
        300       310       320       330         340       350    

             340       350        360       370       380       390
pF1KB9 VAVPPPPPNRMYPPPPPALPSSA-PSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG
           :: :.   :::::  :..  :. ::::  .  :    . :::::::::::::::: 
NP_008 F---PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG----GAPPPPPPPPPPGPPPPPF
             360       370       380           390       400       

              400       410       420       430       440       450
pF1KB9 LPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSV
         .::.  .:        : :  .         ..: :.  ..:. ::. ::::.::. :
NP_008 TGADGQPAIPPP------LSDTTKP--------KSSLPAVSDARSDLLSAIRQGFQLRRV
       410             420               430       440       450   

              460       470       480       490       500     
pF1KB9 ADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
        . .:.          .::  . .. .:  :.. ::   .:::  .: :.:.: :
NP_008 EEQREQE------KRDVVGNDVATILSRRIAVEYSD---SEDDSSEF-DEDDWSD
           460             470       480          490         

>>XP_016857330 (OMIM: 606373,616193) PREDICTED: formin-2  (1102 aa)
 initn: 376 init1: 376 opt: 498  Z-score: 184.7  bits: 44.8 E(85289): 0.0015
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:356-553)

        250       260       270       280       290       300      
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
                                     :::::   .: ::::: :  . :::::  :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
         330       340       350       360       370       380     

        310       320       330         340       350              
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
        : :::::   : :. :::::  :....:::::  .   ::::: ::... :  ::    
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
         390         400        410       420        430       440 

       360       370             380         390       400         
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
         :::: . :.: . ::::      ::::: ::   :::: ::. :    :   :     
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
             450        460       470       480       490       500

     410       420       430       440       450       460         
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
          .  :: .        :.  .:        : ::       :    :: : : .::  
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
               510           520       530       540       550     

     470       480       490       500                             
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED                        
                                                                   
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
         560       570       580       590       600       610     

>>XP_016857329 (OMIM: 606373,616193) PREDICTED: formin-2  (1102 aa)
 initn: 376 init1: 376 opt: 498  Z-score: 184.7  bits: 44.8 E(85289): 0.0015
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:356-553)

        250       260       270       280       290       300      
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
                                     :::::   .: ::::: :  . :::::  :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
         330       340       350       360       370       380     

        310       320       330         340       350              
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
        : :::::   : :. :::::  :....:::::  .   ::::: ::... :  ::    
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
         390         400        410       420        430       440 

       360       370             380         390       400         
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
         :::: . :.: . ::::      ::::: ::   :::: ::. :    :   :     
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
             450        460       470       480       490       500

     410       420       430       440       450       460         
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
          .  :: .        :.  .:        : ::       :    :: : : .::  
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
               510           520       530       540       550     

     470       480       490       500                             
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED                        
                                                                   
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
         560       570       580       590       600       610     

>>XP_016857328 (OMIM: 606373,616193) PREDICTED: formin-2  (1159 aa)
 initn: 376 init1: 376 opt: 498  Z-score: 184.4  bits: 44.9 E(85289): 0.0016
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:413-610)

        250       260       270       280       290       300      
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
                                     :::::   .: ::::: :  . :::::  :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
            390       400       410       420       430       440  

        310       320       330         340       350              
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
        : :::::   : :. :::::  :....:::::  .   ::::: ::... :  ::    
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
            450         460        470       480        490        

       360       370             380         390       400         
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
         :::: . :.: . ::::      ::::: ::   :::: ::. :    :   :     
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
      500       510        520       530       540       550       

     410       420       430       440       450       460         
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
          .  :: .        :.  .:        : ::       :    :: : : .::  
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
       560            570       580       590       600       610  

     470       480       490       500                             
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED                        
                                                                   
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
            620       630       640       650       660       670  

>>XP_011542539 (OMIM: 606373,616193) PREDICTED: formin-2  (1360 aa)
 initn: 376 init1: 376 opt: 498  Z-score: 183.6  bits: 44.9 E(85289): 0.0017
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:980-1177)

        250       260       270       280       290       300      
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
                                     :::::   .: ::::: :  . :::::  :
XP_011 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
     950       960       970       980       990      1000         

        310       320       330         340       350              
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
        : :::::   : :. :::::  :....:::::  .   ::::: ::... :  ::    
XP_011 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
    1010        1020       1030      1040      1050       1060     

       360       370             380         390       400         
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
         :::: . :.: . ::::      ::::: ::   :::: ::. :    :   :     
XP_011 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
        1070       1080      1090      1100      1110      1120    

     410       420       430       440       450       460         
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
          .  :: .        :.  .:        : ::       :    :: : : .::  
XP_011 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
          1130          1140      1150      1160      1170         

     470       480       490       500                             
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED                        
                                                                   
XP_011 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
    1180      1190      1200      1210      1220      1230         

>>XP_016857327 (OMIM: 606373,616193) PREDICTED: formin-2  (1384 aa)
 initn: 376 init1: 376 opt: 498  Z-score: 183.6  bits: 45.0 E(85289): 0.0017
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:980-1177)

        250       260       270       280       290       300      
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
                                     :::::   .: ::::: :  . :::::  :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
     950       960       970       980       990      1000         

        310       320       330         340       350              
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
        : :::::   : :. :::::  :....:::::  .   ::::: ::... :  ::    
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
    1010        1020       1030      1040      1050       1060     

       360       370             380         390       400         
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
         :::: . :.: . ::::      ::::: ::   :::: ::. :    :   :     
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
        1070       1080      1090      1100      1110      1120    

     410       420       430       440       450       460         
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
          .  :: .        :.  .:        : ::       :    :: : : .::  
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
          1130          1140      1150      1160      1170         

     470       480       490       500                             
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED                        
                                                                   
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
    1180      1190      1200      1210      1220      1230         




505 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 19:40:12 2016 done: Sat Nov  5 19:40:14 2016
 Total Scan time: 12.720 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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