Result of FASTA (omim) for pF1KB6181
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6181, 659 aa
  1>>>pF1KB6181 659 - 659 aa - 659 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5355+/-0.000498; mu= 18.2329+/- 0.031
 mean_var=85.1876+/-17.025, 0's: 0 Z-trim(109.1): 203  B-trim: 66 in 1/50
 Lambda= 0.138959
 statistics sampled from 16989 (17231) to 16989 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.202), width:  16
 Scan time: 10.600

The best scores are:                                      opt bits E(85289)
NP_002849 (OMIM: 170995,616278) ATP-binding casset ( 659) 4344 881.9       0
XP_006710865 (OMIM: 170995,616278) PREDICTED: ATP- ( 683) 4116 836.2       0
XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0       0
XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0       0
XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP- ( 586) 3881 789.0       0
XP_011540179 (OMIM: 170995,616278) PREDICTED: ATP- ( 347) 2329 477.7 3.1e-134
NP_001116146 (OMIM: 170995,616278) ATP-binding cas ( 236) 1474 306.2 9.1e-83
NP_005155 (OMIM: 601081) ATP-binding cassette sub- ( 740) 1041 219.7 2.9e-56
XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding ( 740) 1041 219.7 2.9e-56
NP_000024 (OMIM: 300100,300371) ATP-binding casset ( 745) 1031 217.7 1.2e-55
XP_016874481 (OMIM: 601081) PREDICTED: ATP-binding ( 674)  980 207.5 1.3e-52
NP_005041 (OMIM: 603214,614857) ATP-binding casset ( 606)  735 158.3 7.4e-38
XP_005268006 (OMIM: 603214,614857) PREDICTED: ATP- ( 447)  682 147.6 9.3e-35
XP_005268003 (OMIM: 603214,614857) PREDICTED: ATP- ( 447)  682 147.6 9.3e-35
XP_005267996 (OMIM: 603214,614857) PREDICTED: ATP- ( 468)  667 144.6 7.7e-34
XP_005267998 (OMIM: 603214,614857) PREDICTED: ATP- ( 468)  667 144.6 7.7e-34
XP_005267997 (OMIM: 603214,614857) PREDICTED: ATP- ( 468)  667 144.6 7.7e-34
XP_005267999 (OMIM: 603214,614857) PREDICTED: ATP- ( 468)  667 144.6 7.7e-34
XP_011535343 (OMIM: 603214,614857) PREDICTED: ATP- ( 515)  667 144.6 8.3e-34
XP_006720286 (OMIM: 603214,614857) PREDICTED: ATP- ( 519)  661 143.4 1.9e-33
XP_016877023 (OMIM: 603214,614857) PREDICTED: ATP- ( 402)  628 136.7 1.5e-31
XP_016877021 (OMIM: 603214,614857) PREDICTED: ATP- ( 564)  601 131.4 8.6e-30
XP_016877024 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877027 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877031 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877029 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877025 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877030 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877026 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877028 (OMIM: 603214,614857) PREDICTED: ATP- ( 343)  566 124.3 7.6e-28
XP_016877022 (OMIM: 603214,614857) PREDICTED: ATP- ( 550)  566 124.4 1.1e-27
XP_016874483 (OMIM: 601081) PREDICTED: ATP-binding ( 375)  563 123.7 1.2e-27
XP_016874482 (OMIM: 601081) PREDICTED: ATP-binding ( 556)  563 123.8 1.7e-27
XP_016877032 (OMIM: 603214,614857) PREDICTED: ATP- ( 329)  531 117.2 9.5e-26
XP_016877020 (OMIM: 603214,614857) PREDICTED: ATP- ( 572)  471 105.4 6.1e-22
XP_016877033 (OMIM: 603214,614857) PREDICTED: ATP- ( 309)  300 70.9 7.9e-12
NP_001276972 (OMIM: 170261,604571) antigen peptide ( 686)  265 64.1 1.9e-09
NP_000535 (OMIM: 170261,604571) antigen peptide tr ( 703)  264 64.0 2.2e-09
XP_005253346 (OMIM: 239850,601439,608569,614050) P (1536)  267 64.8 2.7e-09
XP_006719088 (OMIM: 239850,601439,608569,614050) P (1536)  267 64.8 2.7e-09
NP_005680 (OMIM: 111600,605452,609153,614497,61540 ( 842)  257 62.6 6.7e-09
XP_016874593 (OMIM: 605453) PREDICTED: ATP-binding ( 485)  245 60.0 2.3e-08
NP_001229942 (OMIM: 605453) ATP-binding cassette s ( 703)  245 60.1 3.1e-08
XP_011536400 (OMIM: 605453) PREDICTED: ATP-binding ( 548)  243 59.7 3.4e-08
XP_005253615 (OMIM: 605453) PREDICTED: ATP-binding ( 548)  243 59.7 3.4e-08
NP_062570 (OMIM: 605453) ATP-binding cassette sub- ( 723)  243 59.8 4.2e-08
XP_016874592 (OMIM: 605453) PREDICTED: ATP-binding ( 766)  243 59.8 4.4e-08
XP_011536398 (OMIM: 605453) PREDICTED: ATP-binding ( 766)  243 59.8 4.4e-08
NP_062571 (OMIM: 605453) ATP-binding cassette sub- ( 766)  243 59.8 4.4e-08
XP_011536397 (OMIM: 605453) PREDICTED: ATP-binding ( 766)  243 59.8 4.4e-08


>>NP_002849 (OMIM: 170995,616278) ATP-binding cassette s  (659 aa)
 initn: 4344 init1: 4344 opt: 4344  Z-score: 4710.3  bits: 881.9 E(85289):    0
Smith-Waterman score: 4344; 100.0% identity (100.0% similar) in 659 aa overlap (1-659:1-659)

               10        20        30        40        50        60
pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 EHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEG
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 VQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 SLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSA
              550       560       570       580       590       600

              610       620       630       640       650         
pF1KB6 VSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS
              610       620       630       640       650         

>>XP_006710865 (OMIM: 170995,616278) PREDICTED: ATP-bind  (683 aa)
 initn: 4116 init1: 4116 opt: 4116  Z-score: 4463.1  bits: 836.2 E(85289):    0
Smith-Waterman score: 4286; 96.5% identity (96.5% similar) in 683 aa overlap (1-659:1-683)

               10        20        30                              
pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHG-----------------------
       :::::::::::::::::::::::::::::::::::::                       
XP_006 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGYFMETWREKSDEVMGELTDHVTH
               10        20        30        40        50        60

         40        50        60        70        80        90      
pF1KB6 -KKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSR
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSR
               70        80        90       100       110       120

        100       110       120       130       140       150      
pF1KB6 TYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV
              130       140       150       160       170       180

        160       170       180       190       200       210      
pF1KB6 RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVL
              190       200       210       220       230       240

        220       230       240       250       260       270      
pF1KB6 YIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNS
              250       260       270       280       290       300

        280       290       300       310       320       330      
pF1KB6 EEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP
              310       320       330       340       350       360

        340       350       360       370       380       390      
pF1KB6 FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQ
              370       380       390       400       410       420

        400       410       420       430       440       450      
pF1KB6 VLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLI
              430       440       450       460       470       480

        460       470       480       490       500       510      
pF1KB6 RDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL
              490       500       510       520       530       540

        520       530       540       550       560       570      
pF1KB6 GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEK
              550       560       570       580       590       600

        580       590       600       610       620       630      
pF1KB6 QRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYY
              610       620       630       640       650       660

        640       650         
pF1KB6 LHMDGRGNYEFKQITEDTVEFGS
       :::::::::::::::::::::::
XP_006 LHMDGRGNYEFKQITEDTVEFGS
              670       680   

>>XP_016857441 (OMIM: 170995,616278) PREDICTED: ATP-bind  (586 aa)
 initn: 3881 init1: 3881 opt: 3881  Z-score: 4209.4  bits: 789.0 E(85289):    0
Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586)

            50        60        70        80        90       100   
pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                     ::::::::::::::::::::::::::::::
XP_016                               MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                             10        20        30

           110       120       130       140       150       160   
pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
               40        50        60        70        80        90

           170       180       190       200       210       220   
pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
              100       110       120       130       140       150

           230       240       250       260       270       280   
pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
              160       170       180       190       200       210

           290       300       310       320       330       340   
pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
              220       230       240       250       260       270

           350       360       370       380       390       400   
pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
              280       290       300       310       320       330

           410       420       430       440       450       460   
pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
              340       350       360       370       380       390

           470       480       490       500       510       520   
pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
              400       410       420       430       440       450

           530       540       550       560       570       580   
pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
              460       470       480       490       500       510

           590       600       610       620       630       640   
pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
              520       530       540       550       560       570

           650         
pF1KB6 NYEFKQITEDTVEFGS
       ::::::::::::::::
XP_016 NYEFKQITEDTVEFGS
              580      

>>XP_016857443 (OMIM: 170995,616278) PREDICTED: ATP-bind  (586 aa)
 initn: 3881 init1: 3881 opt: 3881  Z-score: 4209.4  bits: 789.0 E(85289):    0
Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586)

            50        60        70        80        90       100   
pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                     ::::::::::::::::::::::::::::::
XP_016                               MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                             10        20        30

           110       120       130       140       150       160   
pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
               40        50        60        70        80        90

           170       180       190       200       210       220   
pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
              100       110       120       130       140       150

           230       240       250       260       270       280   
pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
              160       170       180       190       200       210

           290       300       310       320       330       340   
pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
              220       230       240       250       260       270

           350       360       370       380       390       400   
pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
              280       290       300       310       320       330

           410       420       430       440       450       460   
pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
              340       350       360       370       380       390

           470       480       490       500       510       520   
pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
              400       410       420       430       440       450

           530       540       550       560       570       580   
pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
              460       470       480       490       500       510

           590       600       610       620       630       640   
pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
              520       530       540       550       560       570

           650         
pF1KB6 NYEFKQITEDTVEFGS
       ::::::::::::::::
XP_016 NYEFKQITEDTVEFGS
              580      

>>XP_016857442 (OMIM: 170995,616278) PREDICTED: ATP-bind  (586 aa)
 initn: 3881 init1: 3881 opt: 3881  Z-score: 4209.4  bits: 789.0 E(85289):    0
Smith-Waterman score: 3881; 100.0% identity (100.0% similar) in 586 aa overlap (74-659:1-586)

            50        60        70        80        90       100   
pF1KB6 PLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                     ::::::::::::::::::::::::::::::
XP_016                               MVPRTFCKETGYLVLIAVMLVSRTYCDVWM
                                             10        20        30

           110       120       130       140       150       160   
pF1KB6 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLY
               40        50        60        70        80        90

           170       180       190       200       210       220   
pF1KB6 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTS
              100       110       120       130       140       150

           230       240       250       260       270       280   
pF1KB6 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYN
              160       170       180       190       200       210

           290       300       310       320       330       340   
pF1KB6 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHP
              220       230       240       250       260       270

           350       360       370       380       390       400   
pF1KB6 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNH
              280       290       300       310       320       330

           410       420       430       440       450       460   
pF1KB6 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEV
              340       350       360       370       380       390

           470       480       490       500       510       520   
pF1KB6 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQV
              400       410       420       430       440       450

           530       540       550       560       570       580   
pF1KB6 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMAR
              460       470       480       490       500       510

           590       600       610       620       630       640   
pF1KB6 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGRG
              520       530       540       550       560       570

           650         
pF1KB6 NYEFKQITEDTVEFGS
       ::::::::::::::::
XP_016 NYEFKQITEDTVEFGS
              580      

>>XP_011540179 (OMIM: 170995,616278) PREDICTED: ATP-bind  (347 aa)
 initn: 2329 init1: 2329 opt: 2329  Z-score: 2531.0  bits: 477.7 E(85289): 3.1e-134
Smith-Waterman score: 2329; 100.0% identity (100.0% similar) in 347 aa overlap (313-659:1-347)

            290       300       310       320       330       340  
pF1KB6 NGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSH
                                     ::::::::::::::::::::::::::::::
XP_011                               MGFIDSIIAKYLATVVGYLVVSRPFLDLSH
                                             10        20        30

            350       360       370       380       390       400  
pF1KB6 PRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLN
               40        50        60        70        80        90

            410       420       430       440       450       460  
pF1KB6 HGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFE
              100       110       120       130       140       150

            470       480       490       500       510       520  
pF1KB6 VRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQ
              160       170       180       190       200       210

            530       540       550       560       570       580  
pF1KB6 VIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAMA
              220       230       240       250       260       270

            590       600       610       620       630       640  
pF1KB6 RLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWKHHEYYLHMDGR
              280       290       300       310       320       330

            650         
pF1KB6 GNYEFKQITEDTVEFGS
       :::::::::::::::::
XP_011 GNYEFKQITEDTVEFGS
              340       

>>NP_001116146 (OMIM: 170995,616278) ATP-binding cassett  (236 aa)
 initn: 1474 init1: 1474 opt: 1474  Z-score: 1607.0  bits: 306.2 E(85289): 9.1e-83
Smith-Waterman score: 1474; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228)

               10        20        30        40        50        60
pF1KB6 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVS
       ::::::::::::::::::::::::::::::::::::::::::::::::            
NP_001 RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQVLGKILWH    
              190       200       210       220       230          

              250       260       270       280       290       300
pF1KB6 GLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLV

>>NP_005155 (OMIM: 601081) ATP-binding cassette sub-fami  (740 aa)
 initn: 1539 init1: 906 opt: 1041  Z-score: 1131.0  bits: 219.7 E(85289): 2.9e-56
Smith-Waterman score: 1579; 40.3% identity (70.1% similar) in 670 aa overlap (11-650:22-688)

                          10        20           30        40      
pF1KB6            MAAFSKYLTARNSSLAGAAFLLLCL---LHKRRRALGLHGKKSGK--PP
                            : . :..::. :  :   . :: .  : ::::..   : 
NP_005 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPA
               10        20        30        40         50         

               50          60        70        80        90        
pF1KB6 LQNNE----KEGKKERAV--VDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTY
        .:.:     :   :.    :.  ::..:... ::. :.    :::.: : .: :.:::.
NP_005 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF
      60        70        80        90       100       110         

      100        110       120       130       140       150       
pF1KB6 CDVWMIQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVR
        ....   .: ...: .  . :  . . .  .. :.:  ..::. ..:   .: : ::.:
NP_005 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTR
     120       130       140       150        160       170        

       160       170       180       190       200       210       
pF1KB6 LTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLY
       :. . :: :.   ::::. :.:.:.::::: ::.:.  : .::. :::::.::.::..: 
NP_005 LVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLT
      180       190       200       210       220       230        

       220            230         240       250       260       270
pF1KB6 IFKL---TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
        . :   ... ::.  :: ...: :::  ..  :      .::..  : . .:  :::.:
NP_005 SYTLIQTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHS
      240       250        260       270       280       290       

              280       290       300       310       320       330
pF1KB6 RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGY
       :.:.: :::::: :.: : . ... .. :..... ..  :. . .:.... ::. .  : 
NP_005 RIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGL
       300       310       320       330       340       350       

              340            350       360       370       380     
pF1KB6 LVVSRPFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLA
       ..:. :..  .     .  . .   ::  : .  .  .:   ..:. ::. . .:.:.::
NP_005 IMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELA
       360       370       380       390       400       410       

         390       400       410         420           430         
pF1KB6 GFTARITELMQVLKDLNHGKYERTMVSQQEKG--IEGVQV-IPL---IPGAGEIIIADNI
       :.:::. ... :. ....: :.:: : :. ..   .:..: .::   .   :..: .:. 
NP_005 GYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHG
       420       430       440       450       460       470       

     440       450       460       470       480       490         
pF1KB6 IKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTK
       :  ..::. :: :.:.   :::.:. : ..:: ::::::::::::.:. :::.. : : :
NP_005 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK
       480       490       500       510       520       530       

     500       510       520       530       540       550         
pF1KB6 PERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREG
       :   ..::.::::::.::.:::::::::. .:.. :: .:  :.. : ::.: ::..:::
NP_005 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREG
       540       550       560       570       580       590       

     560       570       580       590       600       610         
pF1KB6 GWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGIT
       :::.:.:: :::::::::::.:::.:::::..:.:::::::::.:::: :..  . .::.
NP_005 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGIS
       600       610       620       630       640       650       

     620       630       640       650                             
pF1KB6 LFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS                    
       :....:: ::::.: . :..::.:...:.:.                             
NP_005 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRL
       660       670       680       690       700       710       

NP_005 NELCKILGEDSVLKTIKNEDETS
       720       730       740

>>XP_011536329 (OMIM: 601081) PREDICTED: ATP-binding cas  (740 aa)
 initn: 1539 init1: 906 opt: 1041  Z-score: 1131.0  bits: 219.7 E(85289): 2.9e-56
Smith-Waterman score: 1579; 40.3% identity (70.1% similar) in 670 aa overlap (11-650:22-688)

                          10        20           30        40      
pF1KB6            MAAFSKYLTARNSSLAGAAFLLLCL---LHKRRRALGLHGKKSGK--PP
                            : . :..::. :  :   . :: .  : ::::..   : 
XP_011 MTHMLNAAADRVKWTRSSAAKRAACLVAAAYALKTLYPIIGKRLKQSG-HGKKKAAAYPA
               10        20        30        40         50         

               50          60        70        80        90        
pF1KB6 LQNNE----KEGKKERAV--VDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTY
        .:.:     :   :.    :.  ::..:... ::. :.    :::.: : .: :.:::.
XP_011 AENTEILHCTETICEKPSPGVNADFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTF
      60        70        80        90       100       110         

      100        110       120       130       140       150       
pF1KB6 CDVWMIQ-NGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVR
        ....   .: ...: .  . :  . . .  .. :.:  ..::. ..:   .: : ::.:
XP_011 LSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIP-ATFVNSAIRYLECKLALAFRTR
     120       130       140       150        160       170        

       160       170       180       190       200       210       
pF1KB6 LTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLY
       :. . :: :.   ::::. :.:.:.::::: ::.:.  : .::. :::::.::.::..: 
XP_011 LVDHAYETYFTNQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVMLT
      180       190       200       210       220       230        

       220            230         240       250       260       270
pF1KB6 IFKL---TSAIGAQ--GPASMMAYLVV--SGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
        . :   ... ::.  :: ...: :::  ..  :      .::..  : . .:  :::.:
XP_011 SYTLIQTATSRGASPIGP-TLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHS
      240       250        260       270       280       290       

              280       290       300       310       320       330
pF1KB6 RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGY
       :.:.: :::::: :.: : . ... .. :..... ..  :. . .:.... ::. .  : 
XP_011 RIIANVEEIAFYRGHKVEMKQLQKSYKALADQMNLILSKRLWYIMIEQFLMKYVWSSSGL
       300       310       320       330       340       350       

              340            350       360       370       380     
pF1KB6 LVVSRPFLDLS-----HPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLA
       ..:. :..  .     .  . .   ::  : .  .  .:   ..:. ::. . .:.:.::
XP_011 IMVAIPIITATGFADGEDGQKQVMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELA
       360       370       380       390       400       410       

         390       400       410         420           430         
pF1KB6 GFTARITELMQVLKDLNHGKYERTMVSQQEKG--IEGVQV-IPL---IPGAGEIIIADNI
       :.:::. ... :. ....: :.:: : :. ..   .:..: .::   .   :..: .:. 
XP_011 GYTARVYNMFWVFDEVKRGIYKRTAVIQESESHSKNGAKVELPLSDTLAIKGKVIDVDHG
       420       430       440       450       460       470       

     440       450       460       470       480       490         
pF1KB6 IKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTK
       :  ..::. :: :.:.   :::.:. : ..:: ::::::::::::.:. :::.. : : :
XP_011 IICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYK
       480       490       500       510       520       530       

     500       510       520       530       540       550         
pF1KB6 PERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREG
       :   ..::.::::::.::.:::::::::. .:.. :: .:  :.. : ::.: ::..:::
XP_011 PPPQHMFYIPQRPYMSLGSLRDQVIYPDSVDDMHDKGYTDQDLERILHNVHLYHIVQREG
       540       550       560       570       580       590       

     560       570       580       590       600       610         
pF1KB6 GWDSVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGIT
       :::.:.:: :::::::::::.:::.:::::..:.:::::::::.:::: :..  . .::.
XP_011 GWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAKGAGIS
       600       610       620       630       640       650       

     620       630       640       650                             
pF1KB6 LFTVSHRKSLWKHHEYYLHMDGRGNYEFKQITEDTVEFGS                    
       :....:: ::::.: . :..::.:...:.:.                             
XP_011 LLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRL
       660       670       680       690       700       710       

XP_011 NELCKILGEDSVLKTIKNEDETS
       720       730       740

>>NP_000024 (OMIM: 300100,300371) ATP-binding cassette s  (745 aa)
 initn: 1551 init1: 894 opt: 1031  Z-score: 1120.1  bits: 217.7 E(85289): 1.2e-55
Smith-Waterman score: 1561; 40.1% identity (71.3% similar) in 649 aa overlap (32-650:43-684)

              10        20        30        40        50         60
pF1KB6 AAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEG-KKERAVVD
                                     : ::..  .:.:   ..:  :    .: ..
NP_000 NTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAP-AGEP---TQEASGVAAAKAGMN
             20        30        40         50           60        

               70        80        90       100        110         
pF1KB6 KVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQ-NGTLIESGIIGRSR
       .::..::. .:... ::..:.::: :.: .. :::::. .:.. . .: : .  :. .. 
NP_000 RVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSVYVARLDGRLARC-IVRKDP
       70        80        90       100       110       120        

     120       130        140       150       160       170        
pF1KB6 KDFKRYLLNFI-AAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNL
       . :   ::...  :.:  ..::. ..:  ..: : :: ::. . :. :..  :::...:.
NP_000 RAFGWQLLQWLLIALP-ATFVNSAIRYLEGQLALSFRSRLVAHAYRLYFSQQTYYRVSNM
       130       140        150       160       170       180      

      180       190       200       210       220       230        
pF1KB6 DNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLV
       :.:. :::: ::.::  :  ::. :::::.::.::...  . :  :  ..: ..     .
NP_000 DGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTLLRAARSRGAGTAWPS-A
        190       200       210       220       230       240      

      240             250        260       270       280       290 
pF1KB6 VSGL--FLT----RLRRP-IGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQT
       ..::  :::    :   : .:...  : . .:: ::..::...::::::::.:.. :   
NP_000 IAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVANSEEIAFYGGHEVELAL
         250       260       270       280       290       300     

             300       310       320       330       340           
pF1KB6 VHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDL-----SHPRHL
       ..  .. :. ... ..: :. . ...... ::. .. : :.:. :..       :  . .
NP_000 LQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAVPIITATGYSESDAEAV
         310       320       330       340       350       360     

        350       360                370       380       390       
pF1KB6 KSTHSELLEDYYQSGR---------MLLRMSQALGRIVLAGREMTRLAGFTARITELMQV
       :..  :  :.   : :         .:   ..:. ::. . .:.:.:::.:::. :..::
NP_000 KKAALEKKEEELVSERTEAFTIARNLLTAAADAIERIMSSYKEVTELAGYTARVHEMFQV
         370       380       390       400       410       420     

       400         410           420       430       440       450 
pF1KB6 LKDLN--HGKYERTMVSQQEK----GIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPN
       ..:..  : :  : . . :      :  ::.:   .   :... ... :  ...:..::.
NP_000 FEDVQRCHFKRPRELEDAQAGSGTIGRSGVRVEGPLKIRGQVVDVEQGIICENIPIVTPS
         430       440       450       460       470       480     

             460       470       480       490       500       510 
pF1KB6 GDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQR
       :.:.. .::..:. : ..:: ::::::::::::.:: ::: .:: : ::   ..::.:::
NP_000 GEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTYGGVLYKPPPQRMFYIPQR
         490       500       510       520       530       540     

             520       530       540       550       560       570 
pF1KB6 PYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVL
       :::..:.:::::::::. ::..::: :.  :.  :: :.: :::.:::::... :: :::
NP_000 PYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHHILQREGGWEAMCDWKDVL
         550       560       570       580       590       600     

             580       590       600       610       620       630 
pF1KB6 SGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEGYIYSHCRKVGITLFTVSHRKSLWK
       :::::::..:::.:::.:..:.:::::::::.:::: :..  . .::.:....:: ::::
NP_000 SGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAAKDAGIALLSITHRPSLWK
         610       620       630       640       650       660     

             640       650                                         
pF1KB6 HHEYYLHMDGRGNYEFKQITEDTVEFGS                                
       .: . :..::.:...:...                                         
NP_000 YHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIPKMQRRLQELCQILGEAVA
         670       680       690       700       710       720     




659 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 09:15:19 2016 done: Sat Nov  5 09:15:21 2016
 Total Scan time: 10.600 Total Display time:  0.180

Function used was FASTA [36.3.4 Apr, 2011]
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