Result of FASTA (omim) for pF1KE1010
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE1010, 224 aa
  1>>>pF1KE1010 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.9336+/-0.000325; mu= -1.4335+/- 0.020
 mean_var=283.1938+/-56.313, 0's: 0 Z-trim(124.8): 30  B-trim: 527 in 1/60
 Lambda= 0.076214
 statistics sampled from 47267 (47303) to 47267 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.833), E-opt: 0.2 (0.555), width:  16
 Scan time:  7.620

The best scores are:                                      opt bits E(85289)
NP_001034929 (OMIM: 300922) cysteine-rich hydropho ( 224) 1524 179.7 3.4e-45
NP_001287813 (OMIM: 300922) cysteine-rich hydropho ( 204) 1279 152.7 4.1e-37
XP_016885071 (OMIM: 300922) PREDICTED: cysteine-ri ( 172) 1145 137.9   1e-32
NP_036242 (OMIM: 604332) cysteine-rich hydrophobic ( 165)  941 115.5 5.5e-26
XP_016885072 (OMIM: 300922) PREDICTED: cysteine-ri ( 123)  787 98.4 5.6e-21
XP_016885073 (OMIM: 300922) PREDICTED: cysteine-ri ( 119)  749 94.2   1e-19
XP_011532684 (OMIM: 604332) PREDICTED: cysteine-ri ( 131)  603 78.2 7.2e-15
XP_006714100 (OMIM: 604332) PREDICTED: cysteine-ri ( 137)  369 52.5 4.1e-07


>>NP_001034929 (OMIM: 300922) cysteine-rich hydrophobic   (224 aa)
 initn: 1524 init1: 1524 opt: 1524  Z-score: 932.3  bits: 179.7 E(85289): 3.4e-45
Smith-Waterman score: 1524; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)

               10        20        30        40        50        60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
              130       140       150       160       170       180

              190       200       210       220    
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
       ::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
              190       200       210       220    

>>NP_001287813 (OMIM: 300922) cysteine-rich hydrophobic   (204 aa)
 initn: 1772 init1: 1279 opt: 1279  Z-score: 787.2  bits: 152.7 E(85289): 4.1e-37
Smith-Waterman score: 1335; 91.1% identity (91.1% similar) in 224 aa overlap (1-224:1-204)

               10        20        30        40        50        60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
              130       140       150       160       170       180

              190       200       210       220    
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD
       ::::::::                    ::::::::::::::::
NP_001 ENNRLYHK--------------------VILIEFLPKYPIFRPD
                                  190       200    

>>XP_016885071 (OMIM: 300922) PREDICTED: cysteine-rich h  (172 aa)
 initn: 1145 init1: 1145 opt: 1145  Z-score: 708.5  bits: 137.9 E(85289): 1e-32
Smith-Waterman score: 1145; 100.0% identity (100.0% similar) in 169 aa overlap (1-169:1-169)

               10        20        30        40        50        60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW
       :::::::::::::::::::::::::::::::::::::::::::::::::           
XP_016 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRVWT        
              130       140       150       160       170          

              190       200       210       220    
pF1KE1 ENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD

>>NP_036242 (OMIM: 604332) cysteine-rich hydrophobic dom  (165 aa)
 initn: 970 init1: 923 opt: 941  Z-score: 587.5  bits: 115.5 E(85289): 5.5e-26
Smith-Waterman score: 941; 78.0% identity (91.1% similar) in 168 aa overlap (57-224:5-165)

         30        40        50        60        70        80      
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
                                     .:  ::::.::.:        ::.: .:.:
NP_036                           MADFDEIYEEEEDEERA-------LEEQLLKYSP
                                         10               20       

         90       100       110       120       130       140      
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
       :::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
NP_036 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
        30        40        50        60        70        80       

        150       160       170       180       190       200      
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
       :::::::::::::.::::::.:::::::.::.::::::::::: :::.:.::::::.:::
NP_036 CGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
        90       100       110       120       130       140       

        210       220    
pF1KE1 EYVILIEFLPKYPIFRPD
       ::::::::::: ::::::
NP_036 EYVILIEFLPKTPIFRPD
       150       160     

>>XP_016885072 (OMIM: 300922) PREDICTED: cysteine-rich h  (123 aa)
 initn: 787 init1: 787 opt: 787  Z-score: 497.6  bits: 98.4 E(85289): 5.6e-21
Smith-Waterman score: 787; 95.6% identity (99.1% similar) in 113 aa overlap (112-224:11-123)

              90       100       110       120       130       140 
pF1KE1 RRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVN
                                     .. .:.::::::::::::::::::::::::
XP_016                     MDRGKGEKKLNIAVGEVAPEEFKTSIGRVNACLKKALPVN
                                   10        20        30        40

             150       160       170       180       190       200 
pF1KE1 VKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCE
               50        60        70        80        90       100

             210       220    
pF1KE1 TSNMMEYVILIEFLPKYPIFRPD
       :::::::::::::::::::::::
XP_016 TSNMMEYVILIEFLPKYPIFRPD
              110       120   

>>XP_016885073 (OMIM: 300922) PREDICTED: cysteine-rich h  (119 aa)
 initn: 749 init1: 749 opt: 749  Z-score: 475.2  bits: 94.2 E(85289): 1e-19
Smith-Waterman score: 749; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)

               10        20        30        40        50        60
pF1KE1 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE1 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAP
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::   
XP_016 EEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKKF 
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KE1 EEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEW

>>XP_011532684 (OMIM: 604332) PREDICTED: cysteine-rich h  (131 aa)
 initn: 625 init1: 578 opt: 603  Z-score: 387.9  bits: 78.2 E(85289): 7.2e-15
Smith-Waterman score: 603; 69.4% identity (86.8% similar) in 121 aa overlap (57-177:5-118)

         30        40        50        60        70        80      
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
                                     .:  ::::.::.:        ::.: .:.:
XP_011                           MADFDEIYEEEEDEERA-------LEEQLLKYSP
                                         10               20       

         90       100       110       120       130       140      
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
       :::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: :::::.:::
XP_011 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLL
        30        40        50        60        70        80       

        150       160       170       180       190       200      
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
       :::::::::::::.::::::.::   ..:..                             
XP_011 CGCLCCCCTLGCSMWPVICLSKRITFALQNIFSSLDPQLILSLL                
        90       100       110       120       130                 

        210       220    
pF1KE1 EYVILIEFLPKYPIFRPD

>>XP_006714100 (OMIM: 604332) PREDICTED: cysteine-rich h  (137 aa)
 initn: 474 init1: 351 opt: 369  Z-score: 248.6  bits: 52.5 E(85289): 4.1e-07
Smith-Waterman score: 645; 63.1% identity (74.4% similar) in 168 aa overlap (57-224:5-137)

         30        40        50        60        70        80      
pF1KE1 TSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAP
                                     .:  ::::.::.:        ::.: .:.:
XP_006                           MADFDEIYEEEEDEERA-------LEEQLLKYSP
                                         10               20       

         90       100       110       120       130       140      
pF1KE1 DPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLL
       :::.:::.::.:::::::::..:::: :::::::::::.::.:::.:::: ::::     
XP_006 DPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVN-----
        30        40        50        60        70        80       

        150       160       170       180       190       200      
pF1KE1 CGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMM
                              :::::.::.::::::::::: :::.:.::::::.:::
XP_006 -----------------------TRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMM
                                    90       100       110         

        210       220    
pF1KE1 EYVILIEFLPKYPIFRPD
       ::::::::::: ::::::
XP_006 EYVILIEFLPKTPIFRPD
     120       130       




224 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 13:23:23 2016 done: Sat Nov  5 13:23:24 2016
 Total Scan time:  7.620 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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