Result of FASTA (omim) for pF1KB0067
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB0067, 2442 aa
  1>>>pF1KB0067 2442 - 2442 aa - 2442 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 19.2154+/-0.000536; mu= -39.8269+/- 0.033
 mean_var=901.5913+/-187.803, 0's: 0 Z-trim(124.2): 136  B-trim: 33 in 1/60
 Lambda= 0.042714
 statistics sampled from 45372 (45542) to 45372 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.534), width:  16
 Scan time: 28.550

The best scores are:                                      opt bits E(85289)
NP_004371 (OMIM: 180849,600140) CREB-binding prote (2442) 16860 1056.4       0
XP_016878433 (OMIM: 180849,600140) PREDICTED: CREB (2440) 16831 1054.6       0
XP_011520683 (OMIM: 180849,600140) PREDICTED: CREB (2191) 15122 949.3       0
NP_001073315 (OMIM: 180849,600140) CREB-binding pr (2404) 13906 874.4       0
XP_005255181 (OMIM: 180849,600140) PREDICTED: CREB (2427) 12110 763.7       0
XP_005255182 (OMIM: 180849,600140) PREDICTED: CREB (2303) 10446 661.2 4.5e-188
XP_006720911 (OMIM: 180849,600140) PREDICTED: CREB (2355) 9420 597.9 4.9e-169
XP_011520684 (OMIM: 180849,600140) PREDICTED: CREB (1286) 8701 553.5 6.5e-156
NP_001420 (OMIM: 114500,180849,602700,613684) hist (2414) 6812 437.2 1.2e-120
XP_006724228 (OMIM: 114500,180849,602700,613684) P (2388) 6677 428.9 3.8e-118


>>NP_004371 (OMIM: 180849,600140) CREB-binding protein i  (2442 aa)
 initn: 16860 init1: 16860 opt: 16860  Z-score: 5633.3  bits: 1056.4 E(85289):    0
Smith-Waterman score: 16860; 100.0% identity (100.0% similar) in 2442 aa overlap (1-2442:1-2442)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
             1390      1400      1410      1420      1430      1440

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
             1450      1460      1470      1480      1490      1500

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
             1510      1520      1530      1540      1550      1560

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
             1570      1580      1590      1600      1610      1620

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
             1630      1640      1650      1660      1670      1680

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
             1690      1700      1710      1720      1730      1740

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
             1750      1760      1770      1780      1790      1800

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
             1810      1820      1830      1840      1850      1860

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
             1870      1880      1890      1900      1910      1920

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
             1930      1940      1950      1960      1970      1980

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
             1990      2000      2010      2020      2030      2040

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
             2050      2060      2070      2080      2090      2100

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
             2110      2120      2130      2140      2150      2160

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
             2170      2180      2190      2200      2210      2220

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
             2230      2240      2250      2260      2270      2280

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
             2290      2300      2310      2320      2330      2340

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
             2350      2360      2370      2380      2390      2400

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
NP_004 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
             2410      2420      2430      2440  

>>XP_016878433 (OMIM: 180849,600140) PREDICTED: CREB-bin  (2440 aa)
 initn: 11313 init1: 11313 opt: 16831  Z-score: 5623.6  bits: 1054.6 E(85289):    0
Smith-Waterman score: 16831; 99.9% identity (99.9% similar) in 2442 aa overlap (1-2442:1-2440)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       :::::::::::::::::::::::::::::::::::::::::  :::::::::::::::::
XP_016 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQ--VPGAALPNPLNMLGPQA
              790       800       810       820         830        

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
      840       850       860       870       880       890        

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
      900       910       920       930       940       950        

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
      960       970       980       990      1000      1010        

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
     1020      1030      1040      1050      1060      1070        

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
     1080      1090      1100      1110      1120      1130        

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
     1140      1150      1160      1170      1180      1190        

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
     1200      1210      1220      1230      1240      1250        

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
     1260      1270      1280      1290      1300      1310        

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
     1320      1330      1340      1350      1360      1370        

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
     1380      1390      1400      1410      1420      1430        

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
     1440      1450      1460      1470      1480      1490        

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
     1500      1510      1520      1530      1540      1550        

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
     1560      1570      1580      1590      1600      1610        

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
     1620      1630      1640      1650      1660      1670        

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
     1680      1690      1700      1710      1720      1730        

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
     1740      1750      1760      1770      1780      1790        

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
     1800      1810      1820      1830      1840      1850        

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
     1860      1870      1880      1890      1900      1910        

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
     1920      1930      1940      1950      1960      1970        

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
     1980      1990      2000      2010      2020      2030        

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
     2040      2050      2060      2070      2080      2090        

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
     2100      2110      2120      2130      2140      2150        

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
     2160      2170      2180      2190      2200      2210        

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
     2220      2230      2240      2250      2260      2270        

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
     2280      2290      2300      2310      2320      2330        

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
     2340      2350      2360      2370      2380      2390        

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
XP_016 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
     2400      2410      2420      2430      2440

>>XP_011520683 (OMIM: 180849,600140) PREDICTED: CREB-bin  (2191 aa)
 initn: 15122 init1: 15122 opt: 15122  Z-score: 5055.1  bits: 949.3 E(85289):    0
Smith-Waterman score: 15122; 99.9% identity (99.9% similar) in 2180 aa overlap (263-2442:12-2191)

            240       250       260       270       280       290  
pF1KB0 GASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATG
                                     :  .::::::::::::::::::::::::::
XP_011                    MLSYPEWTCWRGSHQMGITGNTSPFGQPFSQAGGQPMGATG
                                  10        20        30        40 

            300       310       320       330       340       350  
pF1KB0 VNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRK
              50        60        70        80        90       100 

            360       370       380       390       400       410  
pF1KB0 LIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASS
             110       120       130       140       150       160 

            420       430       440       450       460       470  
pF1KB0 RQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSN
             170       180       190       200       210       220 

            480       490       500       510       520       530  
pF1KB0 PNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIP
             230       240       250       260       270       280 

            540       550       560       570       580       590  
pF1KB0 AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGW
             290       300       310       320       330       340 

            600       610       620       630       640       650  
pF1KB0 HEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYH
             350       360       370       380       390       400 

            660       670       680       690       700       710  
pF1KB0 LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV
             410       420       430       440       450       460 

            720       730       740       750       760       770  
pF1KB0 NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQP
             470       480       490       500       510       520 

            780       790       800       810       820       830  
pF1KB0 PNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP
             530       540       550       560       570       580 

            840       850       860       870       880       890  
pF1KB0 LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPV
             590       600       610       620       630       640 

            900       910       920       930       940       950  
pF1KB0 SSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV
             650       660       670       680       690       700 

            960       970       980       990      1000      1010  
pF1KB0 HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE
             710       720       730       740       750       760 

           1020      1030      1040      1050      1060      1070  
pF1KB0 SKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTAS
             770       780       790       800       810       820 

           1080      1090      1100      1110      1120      1130  
pF1KB0 QSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNP
             830       840       850       860       870       880 

           1140      1150      1160      1170      1180      1190  
pF1KB0 MDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPV
             890       900       910       920       930       940 

           1200      1210      1220      1230      1240      1250  
pF1KB0 MQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLG
             950       960       970       980       990      1000 

           1260      1270      1280      1290      1300      1310  
pF1KB0 DDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCL
            1010      1020      1030      1040      1050      1060 

           1320      1330      1340      1350      1360      1370  
pF1KB0 KKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVK
            1070      1080      1090      1100      1110      1120 

           1380      1390      1400      1410      1420      1430  
pF1KB0 PGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYIS
            1130      1140      1150      1160      1170      1180 

           1440      1450      1460      1470      1480      1490  
pF1KB0 YLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQK
            1190      1200      1210      1220      1230      1240 

           1500      1510      1520      1530      1540      1550  
pF1KB0 IPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEES
            1250      1260      1270      1280      1290      1300 

           1560      1570      1580      1590      1600      1610  
pF1KB0 IKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPN
            1310      1320      1330      1340      1350      1360 

           1620      1630      1640      1650      1660      1670  
pF1KB0 VSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLAR
            1370      1380      1390      1400      1410      1420 

           1680      1690      1700      1710      1720      1730  
pF1KB0 DKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINC
            1430      1440      1450      1460      1470      1480 

           1740      1750      1760      1770      1780      1790  
pF1KB0 YNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSL
            1490      1500      1510      1520      1530      1540 

           1800      1810      1820      1830      1840      1850  
pF1KB0 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQ
            1550      1560      1570      1580      1590      1600 

           1860      1870      1880      1890      1900      1910  
pF1KB0 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS
            1610      1620      1630      1640      1650      1660 

           1920      1930      1940      1950      1960      1970  
pF1KB0 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL
            1670      1680      1690      1700      1710      1720 

           1980      1990      2000      2010      2020      2030  
pF1KB0 YRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM
            1730      1740      1750      1760      1770      1780 

           2040      2050      2060      2070      2080      2090  
pF1KB0 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
            1790      1800      1810      1820      1830      1840 

           2100      2110      2120      2130      2140      2150  
pF1KB0 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP
            1850      1860      1870      1880      1890      1900 

           2160      2170      2180      2190      2200      2210  
pF1KB0 GVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQ
            1910      1920      1930      1940      1950      1960 

           2220      2230      2240      2250      2260      2270  
pF1KB0 QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLG
            1970      1980      1990      2000      2010      2020 

           2280      2290      2300      2310      2320      2330  
pF1KB0 QMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPG
            2030      2040      2050      2060      2070      2080 

           2340      2350      2360      2370      2380      2390  
pF1KB0 QQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMA
            2090      2100      2110      2120      2130      2140 

           2400      2410      2420      2430      2440  
pF1KB0 SSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
            2150      2160      2170      2180      2190 

>>NP_001073315 (OMIM: 180849,600140) CREB-binding protei  (2404 aa)
 initn: 13889 init1: 13889 opt: 13906  Z-score: 4649.6  bits: 874.4 E(85289):    0
Smith-Waterman score: 16485; 98.4% identity (98.4% similar) in 2442 aa overlap (1-2442:1-2404)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       :::::::::::::::::::::::::::::::::::::::::::::.              
NP_001 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQA--------------
              370       380       390       400                    

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
                               ::::::::::::::::::::::::::::::::::::
NP_001 ------------------------ILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
                                410       420       430       440  

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
            450       460       470       480       490       500  

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
            510       520       530       540       550       560  

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
            570       580       590       600       610       620  

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
            630       640       650       660       670       680  

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
            690       700       710       720       730       740  

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
            750       760       770       780       790       800  

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
            810       820       830       840       850       860  

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
            870       880       890       900       910       920  

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
            930       940       950       960       970       980  

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
            990      1000      1010      1020      1030      1040  

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
           1050      1060      1070      1080      1090      1100  

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
           1110      1120      1130      1140      1150      1160  

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
           1170      1180      1190      1200      1210      1220  

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
           1230      1240      1250      1260      1270      1280  

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
           1290      1300      1310      1320      1330      1340  

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
           1350      1360      1370      1380      1390      1400  

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
           1410      1420      1430      1440      1450      1460  

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
           1470      1480      1490      1500      1510      1520  

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
           1530      1540      1550      1560      1570      1580  

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
           1590      1600      1610      1620      1630      1640  

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
           1650      1660      1670      1680      1690      1700  

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
           1710      1720      1730      1740      1750      1760  

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
           1770      1780      1790      1800      1810      1820  

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
           1830      1840      1850      1860      1870      1880  

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
           1890      1900      1910      1920      1930      1940  

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
           1950      1960      1970      1980      1990      2000  

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
           2010      2020      2030      2040      2050      2060  

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
           2070      2080      2090      2100      2110      2120  

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
           2130      2140      2150      2160      2170      2180  

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
           2190      2200      2210      2220      2230      2240  

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
           2250      2260      2270      2280      2290      2300  

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
           2310      2320      2330      2340      2350      2360  

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
NP_001 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
           2370      2380      2390      2400    

>>XP_005255181 (OMIM: 180849,600140) PREDICTED: CREB-bin  (2427 aa)
 initn: 16738 init1: 12021 opt: 12110  Z-score: 4051.4  bits: 763.7 E(85289):    0
Smith-Waterman score: 16711; 99.3% identity (99.3% similar) in 2442 aa overlap (1-2442:1-2427)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::                
XP_005 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPR---------------
              670       680       690       700                    

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
         710       720       730       740       750       760     

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
         770       780       790       800       810       820     

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
         830       840       850       860       870       880     

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
         890       900       910       920       930       940     

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
         950       960       970       980       990      1000     

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
        1010      1020      1030      1040      1050      1060     

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
        1070      1080      1090      1100      1110      1120     

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
        1130      1140      1150      1160      1170      1180     

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
        1190      1200      1210      1220      1230      1240     

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
        1250      1260      1270      1280      1290      1300     

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
        1310      1320      1330      1340      1350      1360     

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
        1370      1380      1390      1400      1410      1420     

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
        1430      1440      1450      1460      1470      1480     

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
        1490      1500      1510      1520      1530      1540     

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
        1550      1560      1570      1580      1590      1600     

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
        1610      1620      1630      1640      1650      1660     

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
        1670      1680      1690      1700      1710      1720     

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
        1730      1740      1750      1760      1770      1780     

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
        1790      1800      1810      1820      1830      1840     

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
        1850      1860      1870      1880      1890      1900     

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
        1910      1920      1930      1940      1950      1960     

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
        1970      1980      1990      2000      2010      2020     

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
        2030      2040      2050      2060      2070      2080     

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
        2090      2100      2110      2120      2130      2140     

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
        2150      2160      2170      2180      2190      2200     

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
        2210      2220      2230      2240      2250      2260     

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
        2270      2280      2290      2300      2310      2320     

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
        2330      2340      2350      2360      2370      2380     

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
        2390      2400      2410      2420       

>>XP_005255182 (OMIM: 180849,600140) PREDICTED: CREB-bin  (2303 aa)
 initn: 10348 init1: 10348 opt: 10446  Z-score: 3497.5  bits: 661.2 E(85289): 4.5e-188
Smith-Waterman score: 15593; 94.3% identity (94.3% similar) in 2442 aa overlap (1-2442:1-2303)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       :::::::::::::::::::::::::::::::::::::::::                   
XP_005 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQ-------------------
              790       800       810       820                    

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
                                                                   
XP_005 ------------------------------------------------------------
                                                                   

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
                                                                   
XP_005 ------------------------------------------------------------
                                                                   

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
             830       840       850       860       870       880 

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
             890       900       910       920       930       940 

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
             950       960       970       980       990      1000 

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
            1010      1020      1030      1040      1050      1060 

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
            1070      1080      1090      1100      1110      1120 

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
            1130      1140      1150      1160      1170      1180 

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
            1190      1200      1210      1220      1230      1240 

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
            1250      1260      1270      1280      1290      1300 

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
            1310      1320      1330      1340      1350      1360 

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
            1370      1380      1390      1400      1410      1420 

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
            1430      1440      1450      1460      1470      1480 

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
            1490      1500      1510      1520      1530      1540 

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
            1550      1560      1570      1580      1590      1600 

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
            1610      1620      1630      1640      1650      1660 

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
            1670      1680      1690      1700      1710      1720 

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
            1730      1740      1750      1760      1770      1780 

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
            1790      1800      1810      1820      1830      1840 

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
            1850      1860      1870      1880      1890      1900 

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
            1910      1920      1930      1940      1950      1960 

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
            1970      1980      1990      2000      2010      2020 

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
            2030      2040      2050      2060      2070      2080 

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
            2090      2100      2110      2120      2130      2140 

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
            2150      2160      2170      2180      2190      2200 

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
            2210      2220      2230      2240      2250      2260 

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
XP_005 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
            2270      2280      2290      2300   

>>XP_006720911 (OMIM: 180849,600140) PREDICTED: CREB-bin  (2355 aa)
 initn: 9698 init1: 9395 opt: 9420  Z-score: 3155.7  bits: 597.9 E(85289): 4.9e-169
Smith-Waterman score: 16069; 96.4% identity (96.4% similar) in 2442 aa overlap (1-2442:1-2355)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KB0 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::  
XP_006 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSR--
             1330      1340      1350      1360      1370          

             1390      1400      1410      1420      1430      1440
pF1KB0 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
                                                                   
XP_006 ------------------------------------------------------------
                                                                   

             1450      1460      1470      1480      1490      1500
pF1KB0 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
                                :::::::::::::::::::::::::::::::::::
XP_006 -------------------------YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
                              1380      1390      1400      1410   

             1510      1520      1530      1540      1550      1560
pF1KB0 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
          1420      1430      1440      1450      1460      1470   

             1570      1580      1590      1600      1610      1620
pF1KB0 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
          1480      1490      1500      1510      1520      1530   

             1630      1640      1650      1660      1670      1680
pF1KB0 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
          1540      1550      1560      1570      1580      1590   

             1690      1700      1710      1720      1730      1740
pF1KB0 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
          1600      1610      1620      1630      1640      1650   

             1750      1760      1770      1780      1790      1800
pF1KB0 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
          1660      1670      1680      1690      1700      1710   

             1810      1820      1830      1840      1850      1860
pF1KB0 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
          1720      1730      1740      1750      1760      1770   

             1870      1880      1890      1900      1910      1920
pF1KB0 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
          1780      1790      1800      1810      1820      1830   

             1930      1940      1950      1960      1970      1980
pF1KB0 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
          1840      1850      1860      1870      1880      1890   

             1990      2000      2010      2020      2030      2040
pF1KB0 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
          1900      1910      1920      1930      1940      1950   

             2050      2060      2070      2080      2090      2100
pF1KB0 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
          1960      1970      1980      1990      2000      2010   

             2110      2120      2130      2140      2150      2160
pF1KB0 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
          2020      2030      2040      2050      2060      2070   

             2170      2180      2190      2200      2210      2220
pF1KB0 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
          2080      2090      2100      2110      2120      2130   

             2230      2240      2250      2260      2270      2280
pF1KB0 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
          2140      2150      2160      2170      2180      2190   

             2290      2300      2310      2320      2330      2340
pF1KB0 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
          2200      2210      2220      2230      2240      2250   

             2350      2360      2370      2380      2390      2400
pF1KB0 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
          2260      2270      2280      2290      2300      2310   

             2410      2420      2430      2440  
pF1KB0 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
       ::::::::::::::::::::::::::::::::::::::::::
XP_006 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
          2320      2330      2340      2350     

>>XP_011520684 (OMIM: 180849,600140) PREDICTED: CREB-bin  (1286 aa)
 initn: 8701 init1: 8701 opt: 8701  Z-score: 2920.1  bits: 553.5 E(85289): 6.5e-156
Smith-Waterman score: 8701; 99.7% identity (99.8% similar) in 1285 aa overlap (1-1285:1-1285)

               10        20        30        40        50        60
pF1KB0 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB0 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB0 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB0 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB0 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB0 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB0 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB0 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB0 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB0 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB0 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB0 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB0 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB0 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KB0 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KB0 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KB0 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KB0 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KB0 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KB0 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KB0 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KB0 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
       ::::::::::::::::::: .  ::                                   
XP_011 TISKDQFEKKKNDTLDPEPEIGRKEE                                  
             1270      1280                                        

>>NP_001420 (OMIM: 114500,180849,602700,613684) histone   (2414 aa)
 initn: 7325 init1: 3547 opt: 6812  Z-score: 2287.0  bits: 437.2 E(85289): 1.2e-120
Smith-Waterman score: 9748; 60.9% identity (78.5% similar) in 2517 aa overlap (1-2431:1-2400)

                10        20          30        40        50       
pF1KB0 MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG
       ::::... :::. :: :::::..::.  :.::::::::::.::::::: :. :::: :.:
NP_001 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG
               10        20        30        40         50         

                 60        70        80        90       100        
pF1KB0 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN
       .         .: ::::::::::::::.::. ..: :.:.     :   :    .:.: .
NP_001 DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG-----P---GQVMASQAQQS
      60        70        80        90            100          110 

      110       120       130       140       150       160        
pF1KB0 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT
       : ... ...: :::..:.  ..:..   . .::::. . .:.        .:. .:    
NP_001 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ
             120       130          140       150               160

      170       180       190       200       210       220        
pF1KB0 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT
          : .  :::..:   ::.: ...:.... .      ::::::.:: ::::  .: ::.
NP_001 PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN
              170          180             190        200          

      230       240       250       260       270       280        
pF1KB0 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM
       :.: :.....:.: : : :::: :..::   :     :::. .: .:.:.:..:  :: .
NP_001 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI
     210        220       230       240          250       260     

      290       300       310       320            330        340  
pF1KB0 GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ-----MQTSVGIVPT-QAIAT
       ::.:.. :. .:  . :.:  :  : : .   ..:::.:     .:    ..:. :....
NP_001 GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS
         270       280       290       300       310       320     

             350       360       370       380       390       400 
pF1KB0 GP-TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG
       :  :::::::::::::::::::::::::::::::::: :.::::::::::::::::::.:
NP_001 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG
         330       340       350       360       370       380     

             410       420       430       440        450       460
pF1KB0 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTIL-GSPASGIQNTIGSV
       :.:::::::::::::::::::::::::::::::::.:::::: :: :.:. :. :  .:.
NP_001 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL
         390       400       410       420       430        440    

              470       480       490        500       510         
pF1KB0 GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM
       :.:::.: .::. . :::::..:::::::::: .::  :: : :. .::  :: :. : :
NP_001 GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM
           450       460       470       480       490       500   

      520       530       540       550       560       570        
pF1KB0 RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
       : .. .. .::..  ::. .  : :.:.:.: : ..... ::.:   :..... .:. .:
NP_001 RPMSNMSASPMGV-NGGVGV--QTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP
           510        520         530       540          550       

      580       590       600       610       620       630        
pF1KB0 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
       ::: ::.::.:: ::: .:::::.:::::::::::::::::::::::::::::::.::::
NP_001 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG
       560       570       580       590       600       610       

      640       650       660       670       680       690        
pF1KB0 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ
       :::::::.: ::::::::::::::::::::::.::.::..: :  ..   . .: : . :
NP_001 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ
       620       630       640       650       660       670       

       700       710         720           730       740       750 
pF1KB0 AQPVRPPNGPLSLP-VNRMQV-SQGMNSFNPMS----LGNVQLPQAPMGPRAASPMNHSV
        ::    ::::  : . : .: .: :  ..:.:    .:.... : :. :: . :..:  
NP_001 PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMAQPPIVPRQTPPLQHHG
       680       690       700       710       720       730       

              760       770       780       790       800          
pF1KB0 QMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GAMSVG
       :. . :.. : :. .: :: :: :               :.:::::.::::.. .. .. 
NP_001 QLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNVTNIP
       740       750        760                      770       780 

     810       820       830         840       850          860    
pF1KB0 MGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPASTAA
       ..   .:. :::.:. ... :  .:.   : :.:.. :: . :  ::   :.: :. : .
NP_001 LAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPT
             790       800       810       820       830       840 

             870       880       890       900       910       920 
pF1KB0 GM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA
            ::.    ::. : : :. :: :. : . ..:.  : : ..:.   ::    :: .
NP_001 PHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPS
             850       860        870       880       890       900

              930       940       950        960       970         
pF1KB0 AQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTPSSVA
         :  .  :::   :: :  .  .:   :: :.    :.::::: :.::...: .: :..
NP_001 LPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTS
              910         920       930       940       950        

     980       990      1000      1010      1020      1030         
pF1KB0 SAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIA
       :.:.:::  .   :  :.: :.. :  .:.:...  .:      ::..       :. . 
NP_001 STEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADT--QP------EDIS-------ESKVE
      960       970       980       990                     1000   

    1040      1050      1060      1070      1080      1090         
pF1KB0 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLE
       . : :  :..:.. :.:.:.::::.. :......: .:.: .::::::::::::::::::
NP_001 DCKMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLE
          1010      1020      1030      1040      1050      1060   

    1100      1110      1120      1130      1140      1150         
pF1KB0 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWL
       :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::.::
NP_001 ALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWL
          1070      1080      1090      1100      1110      1120   

    1160      1170      1180      1190      1200      1210         
pF1KB0 MFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLC
       :::::::::::::::::.::::.::::::::::::::::::::: :::::::::::::::
NP_001 MFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLC
          1130      1140      1150      1160      1170      1180   

    1220      1230      1240      1250      1260      1270         
pF1KB0 TIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEP
       ::::::.:::::::::::::::.:::::.:.::::::::::::.:.:: :.:::::::: 
NP_001 TIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPEL
          1190      1200      1210      1220      1230      1240   

    1280      1290      1300      1310      1320      1330         
pF1KB0 FVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLE
       ::.: :::::::::::::..::::.:::::.::::..: ::::::::::: .::::. ::
NP_001 FVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLE
          1250      1260      1270      1280      1290      1300   

    1340      1350      1360      1370      1380      1390         
pF1KB0 DRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAF
       .::: :::::::::.::: :::: .::::::::::::.::::::::.:::::::::::::
NP_001 NRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAF
          1310      1320      1330      1340      1350      1360   

    1400      1410      1420      1430      1440      1450         
pF1KB0 EEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLE
       :::::::.:::::::::::::::::: ::::::::::.:::::.::::::::::::::::
NP_001 EEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLE
          1370      1380      1390      1400      1410      1420   

    1460      1470      1480      1490      1500      1510         
pF1KB0 YVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDY
       :::::::.::::::::::::::::::::::::::::::::::::::::::: .:::.:::
NP_001 YVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDY
          1430      1440      1450      1460      1470      1480   

    1520      1530      1540      1550      1560      1570         
pF1KB0 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQ
       :::::::::::::::::::::::::::::::::::::::::::::.::.:. .:.:. ..
NP_001 KDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTS-NESTDVTK
          1490      1500      1510      1520      1530       1540  

    1580      1590      1600      1610      1620      1630         
pF1KB0 GDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHA
       ::::::::::::::.:::::.::.:::::.::::::::::::::::::::::::::.: :
NP_001 GDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIA
           1550      1560      1570      1580      1590      1600  

    1640      1650      1660      1670      1680      1690         
pF1KB0 GPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQG
       ::. :.::::::::::. :::::::::::::::::: :::::::..:::.:::::::::.
NP_001 GPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQS
           1610      1620      1630      1640      1650      1660  

    1700      1710      1720      1730      1740      1750         
pF1KB0 QDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEP
       :::::::::::::::::::::::::::::::.:::::.: ::: : :::::::...:   
NP_001 QDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAA
           1670      1680      1690      1700      1710      1720  

    1760      1770      1780      1790      1800      1810         
pF1KB0 QSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVC
        ..:: .:::::::::::::::::::::::::::::::::::::::::::::::::::.:
NP_001 ATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPIC
           1730      1740      1750      1760      1770      1780  

    1820      1830      1840      1850      1860      1870         
pF1KB0 KQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNV--
       ::::::::::::::::::::::::::::.::::::.::::::::..:::::.:.  .:  
NP_001 KQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVG
           1790      1800      1810      1820      1830      1840  

      1880      1890       1900      1910      1920      1930      
pF1KB0 PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG
        ::.::::: : : ::: :::.::::::: .::::.: .  :   : . :::    :: :
NP_001 QQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGPVSQG
           1850      1860      1870      1880         1890         

       1940        1950           1960      1970      1980         
pF1KB0 KPTSQV--PAPPPPAQPP-----PAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG
       : ..::  :.::  ::::     ::::: : ::.: :. :... .:.: .   : .  : 
NP_001 KAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQM-
    1900      1910      1920      1930      1940      1950         

    1990      2000       2010       2020            2030      2040 
pF1KB0 TPGSQMAPVSLNVPRPNQ-VSGPVMPSM-PPGQWQQAP-----LPQ-QQPMPGLPRPVIS
        : . :::...: :  ..  :: . :.: : :. :: :     ::: :: . :.:::.. 
NP_001 PPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMM
       1960      1970      1980      1990      2000      2010      

                   2050        2060      2070      2080      2090  
pF1KB0 MQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKS
         ::       :   :  . ...:  : ..: .:::.:::::.::::: ::::::.::..
NP_001 SVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHA
       2020      2030      2040      2050      2060      2070      

           2100      2110       2120            2130      2140     
pF1KB0 NPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQPSLQNLNAM
       ::::.:::::::.:::. ..:   : :::. :.:::.::     : :.:..:..::.: :
NP_001 NPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPM
       2080      2090      2100      2110      2120      2130      

        2150            2160      2170      2180      2190         
pF1KB0 QAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQ
       :::: : :.:   ::::    :::..::.: .: ::  ::    .:  :.:..::::   
NP_001 QAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQMN-MN--HN----TMPSQFRDILRRQ---
       2140      2150      2160       2170            2180         

    2200      2210      2220      2230      2240      2250         
pF1KB0 QQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS
              :..:::::: .. :.. :::.:.::::::: : :::  :::::::.:.    .
NP_001 -------QMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPP--QQQQRMQHHM----Q
              2190      2200      2210       2220        2230      

    2260      2270      2280      2290      2300      2310         
pF1KB0 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQH
       .: :  ..:::.::. : .:::..  ..: : :::.::::     .::: ::::::::::
NP_001 QMQQ--GNMGQIGQLPQ-ALGAEAGASLQ-AYQQRLLQQQ-----MGSPVQPNPMSPQQH
             2240       2250       2260           2270      2280   

    2320      2330      2340      2350      2360      2370         
pF1KB0 MLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ
       :: .: :. :: :::: .::::::::: :: ::::::::::::::::.::::::::::::
NP_001 MLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQ
          2290      2300      2310      2320      2330      2340   

    2380      2390      2400      2410       2420          2430    
pF1KB0 TGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNT-PSRSAL----SSELSLVGDTTGDT
       :.::::::....:. ..:::...:.:..:: :: . :. . :    ...:.:  :..   
NP_001 TSSPHPGLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLN
          2350      2360      2370      2380      2390      2400   

         2440     
pF1KB0 LEKFVEGL   
                  
NP_001 SNLSQSTLDIH
          2410    

>>XP_006724228 (OMIM: 114500,180849,602700,613684) PREDI  (2388 aa)
 initn: 7272 init1: 3547 opt: 6677  Z-score: 2242.1  bits: 428.9 E(85289): 3.8e-118
Smith-Waterman score: 9693; 60.7% identity (78.4% similar) in 2511 aa overlap (1-2431:1-2374)

                10        20          30        40        50       
pF1KB0 MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG
       ::::... :::. :: :::::..::.  :.::::::::::.::::::: :. :::: :.:
XP_006 MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG
               10        20        30        40         50         

                 60        70        80        90       100        
pF1KB0 N---------LVPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN
       .         .: ::::::::::::::.::. ..: :.:.     :   :    .:.: .
XP_006 DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG-----P---GQVMASQAQQS
      60        70        80        90            100          110 

      110       120       130       140       150       160        
pF1KB0 SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT
       : ... ...: :::..:.  ..:..   . .::::. . .:.        .:. .:    
XP_006 SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ
             120       130          140       150               160

      170       180       190       200       210       220        
pF1KB0 SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT
          : .  :::..:   ::.: ...:.... .      ::::::.:: ::::  .: ::.
XP_006 PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN
              170          180             190        200          

      230       240       250       260       270       280        
pF1KB0 PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM
       :.: :.....:.: : : :::: :..::   :     :::. .: .:.:.:..:  :: .
XP_006 PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI
     210        220       230       240          250       260     

      290       300       310       320            330        340  
pF1KB0 GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQ-----MQTSVGIVPT-QAIAT
       ::.:.. :. .:  . :.:  :  : : .   ..:::.:     .:    ..:. :....
XP_006 GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS
         270       280       290       300       310       320     

             350       360       370       380       390       400 
pF1KB0 GP-TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG
       :  :::::::::::::::::::::::::::::::::: :.::::::::::::::::::.:
XP_006 GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG
         330       340       350       360       370       380     

             410       420       430       440        450       460
pF1KB0 KACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTIL-GSPASGIQNTIGSV
       :.:::::::::::::::::::::::::::::::::.:::::: :: :.:. :. :  .:.
XP_006 KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL
         390       400       410       420       430        440    

              470       480       490        500       510         
pF1KB0 GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM
       :.:::.: .::. . :::::..:::::::::: .::  :: : :. .::  :: :. : :
XP_006 GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM
           450       460       470       480       490       500   

      520       530       540       550       560       570        
pF1KB0 RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
       : .. .. .::..  ::. .  : :.:.:.: : ..... ::.:   :..... .:. .:
XP_006 RPMSNMSASPMGV-NGGVGV--QTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP
           510        520         530       540          550       

      580       590       600       610       620       630        
pF1KB0 TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
       ::: ::.::.:: ::: .:::::.:::::::::::::::::::::::::::::::.::::
XP_006 TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG
       560       570       580       590       600       610       

      640       650       660       670       680       690        
pF1KB0 DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ
       :::::::.: ::::::::::::::::::::::.::.::..: :  ..   . .: : . :
XP_006 DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ
       620       630       640       650       660       670       

       700       710       720       730       740       750       
pF1KB0 AQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMG
        ::     :          .....:.:. ::..     : :. :: . :..:  :. . :
XP_006 PQP-----G----------MTSSLNQFGQMSMA-----QPPIVPRQTPPLQHHGQLAQPG
       680                      690            700       710       

        760       770       780       790       800        810     
pF1KB0 SV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-GAMSVGMGQPPA
       .. : :. .: :: :: :               :.:::::.::::.. .. .. ..   .
XP_006 ALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMNVTNIPLAPSSG
       720        730                      740       750       760 

         820       830         840       850          860          
pF1KB0 QTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPPASTAAGM---P
       :. :::.:. ... :  .:.   : :.:.. :: . :  ::   :.: :. : .     :
XP_006 QAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPP
             770       780       790       800       810       820 

       870       880       890       900       910       920       
pF1KB0 SLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVT
       :.    ::. : : :. :: :. : . ..:.  : : ..:.   ::    :: .  :  .
XP_006 SIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPS
             830        840       850       860       870       880

        930       940       950        960       970       980     
pF1KB0 P-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNS
         :::   :: :  .  .:   :: :.    :.::::: :.::...: .: :..:.:.::
XP_006 ADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNS
                890       900       910       920       930        

         990      1000      1010      1020      1030      1040     
pF1KB0 QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP
       :  .   :  :.: :.. :  .:.:...  .:      ::..       :. . . : : 
XP_006 QAIAEKQPSQEVKMEAKMEVDQPEPADT--QP------EDIS-------ESKVEDCKMES
      940       950       960               970              980   

        1050      1060      1070      1080      1090      1100     
pF1KB0 MEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQD
        :..:.. :.:.:.::::.. :......: .:.: .::::::::::::::::::::::::
XP_006 TETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQALMPTLEALYRQD
           990      1000      1010      1020      1030      1040   

        1110      1120      1130      1140      1150      1160     
pF1KB0 PESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAW
       :::::::::::::::::::::::::.:::::::::::::::::::::::::.::::::::
XP_006 PESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYVDDIWLMFNNAW
          1050      1060      1070      1080      1090      1100   

        1170      1180      1190      1200      1210      1220     
pF1KB0 LYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDA
       :::::::::::.::::.::::::::::::::::::::: :::::::::::::::::::::
XP_006 LYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCYGKQLCTIPRDA
          1110      1120      1130      1140      1150      1160   

        1230      1240      1250      1260      1270      1280     
pF1KB0 AYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKE
       .:::::::::::::::.:::::.:.::::::::::::.:.:: :.:::::::: ::.: :
XP_006 TYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDTLDPELFVECTE
          1170      1180      1190      1200      1210      1220   

        1290      1300      1310      1320      1330      1340     
pF1KB0 CGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKF
       ::::::::::::..::::.:::::.::::..: ::::::::::: .::::. ::.::: :
XP_006 CGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRLGTFLENRVNDF
          1230      1240      1250      1260      1270      1280   

        1350      1360      1370      1380      1390      1400     
pF1KB0 LRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGV
       ::::::::.::: :::: .::::::::::::.::::::::.:::::::::::::::::::
XP_006 LRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTKALFAFEEIDGV
          1290      1300      1310      1320      1330      1340   

        1410      1420      1430      1440      1450      1460     
pF1KB0 DVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLG
       :.:::::::::::::::::: ::::::::::.:::::.::::::::::::::::::::::
XP_006 DLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEILIGYLEYVKKLG
          1350      1360      1370      1380      1390      1400   

        1470      1480      1490      1500      1510      1520     
pF1KB0 YVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQ
       :.::::::::::::::::::::::::::::::::::::::::::: .:::.:::::::::
XP_006 YTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSERIVHDYKDIFKQ
          1410      1420      1430      1440      1450      1460   

        1530      1540      1550      1560      1570      1580     
pF1KB0 ATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNA
       :::::::::::::::::::::::::::::::::::::::.::.:. .:.:. ..::::::
XP_006 ATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENTS-NESTDVTKGDSKNA
          1470      1480      1490      1500       1510      1520  

        1590      1600      1610      1620      1630      1640     
pF1KB0 KKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINT
       ::::::::.:::::.::.:::::.::::::::::::::::::::::::::.: :::. :.
XP_006 KKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFVIRLIAGPAANS
           1530      1540      1550      1560      1570      1580  

        1650      1660      1670      1680      1690      1700     
pF1KB0 LPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVY
       ::::::::::. :::::::::::::::::: :::::::..:::.:::::::::.::::::
XP_006 LPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVELHTQSQDRFVY
           1590      1600      1610      1620      1630      1640  

        1710      1720      1730      1740      1750      1760     
pF1KB0 TCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQ
       :::::::::::::::::::::::::.:::::.: ::: : :::::::...:    ..:: 
XP_006 TCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESNNQQAAATQSPG
           1650      1660      1670      1680      1690      1700  

        1770      1780      1790      1800      1810      1820     
pF1KB0 ESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIAL
       .:::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_006 DSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPICKQLIAL
           1710      1720      1730      1740      1750      1760  

        1830      1840      1850      1860      1870        1880   
pF1KB0 CCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNV--PQQSLP
       ::::::::::::::::::::::.::::::.::::::::..:::::.:.  .:   ::.::
XP_006 CCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLP
           1770      1780      1790      1800      1810      1820  

          1890       1900      1910      1920      1930      1940  
pF1KB0 SPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV
       ::: : : ::: :::.::::::: .::::.: .  :   : . :::    :: :: ..::
XP_006 SPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAGPVSQGKAAGQV
           1830      1840      1850         1860      1870         

             1950           1960      1970      1980      1990     
pF1KB0 --PAPPPPAQPP-----PAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM
         :.::  ::::     ::::: : ::.: :. :... .:.: .   : .  :  : . :
XP_006 TPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQR--PIQHQM-PPMTPM
    1880      1890      1900      1910      1920        1930       

        2000       2010       2020            2030      2040       
pF1KB0 APVSLNVPRPNQ-VSGPVMPSM-PPGQWQQAP-----LPQ-QQPMPGLPRPVISMQAQ--
       ::...: :  ..  :: . :.: : :. :: :     ::: :: . :.:::..   ::  
XP_006 APMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHG
       1940      1950      1960      1970      1980      1990      

             2050        2060      2070      2080      2090        
pF1KB0 -----AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMA
            :   :  . ...:  : ..: .:::.:::::.::::: ::::::.::..::::.:
XP_006 QPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLA
       2000      2010      2020      2030      2040      2050      

     2100      2110       2120            2130      2140      2150 
pF1KB0 AFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQQPSLQNLNAMQAGVPR
       ::::::.:::. ..:   : :::. :.:::.::     : :.:..:..::.: ::::: :
XP_006 AFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGVQR
       2060      2070      2080      2090      2100      2110      

                  2160      2170      2180      2190      2200     
pF1KB0 PGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQ
        :.:   ::::    :::..::.: .: ::  ::    .:  :.:..::::         
XP_006 AGLPQQQPQQQLQPPMGGMSPQAQQMN-MN--HN----TMPSQFRDILRRQ---------
       2120      2130      2140             2150      2160         

        2210      2220      2230      2240      2250      2260     
pF1KB0 QQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMA
        :..:::::: .. :.. :::.:.::::::: : :::  :::::::.:.    ..: :  
XP_006 -QMMQQQQQQGAGPGIGPGMANHNQFQQPQGVG-YPP--QQQQRMQHHM----QQMQQ--
              2170      2180      2190         2200          2210  

        2270      2280      2290      2300      2310      2320     
pF1KB0 AQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQP
       ..:::.::. : .:::..  ..: : :::.::::     .::: :::::::::::: .: 
XP_006 GNMGQIGQLPQ-ALGAEAGASLQ-AYQQRLLQQQ-----MGSPVQPNPMSPQQHMLPNQA
             2220       2230       2240           2250      2260   

        2330      2340      2350      2360      2370      2380     
pF1KB0 QASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP
       :. :: :::: .::::::::: :: ::::::::::::::::.:::::::::::::.::::
XP_006 QSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHP
          2270      2280      2290      2300      2310      2320   

        2390      2400      2410       2420          2430      2440
pF1KB0 GLAVTMASSIDQGHLGNPEQSAMLPQLNT-PSRSAL----SSELSLVGDTTGDTLEKFVE
       ::....:. ..:::...:.:..:: :: . :. . :    ...:.:  :..         
XP_006 GLVAAQANPMEQGHFASPDQNSMLSQLASNPGMANLHGASATDLGLSTDNSDLNSNLSQS
          2330      2340      2350      2360      2370      2380   

            
pF1KB0 GL   
            
XP_006 TLDIH
            




2442 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 20:22:17 2016 done: Sun Nov  6 20:22:21 2016
 Total Scan time: 28.550 Total Display time:  2.480

Function used was FASTA [36.3.4 Apr, 2011]
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