Result of FASTA (omim) for pF1KB4334
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4334, 473 aa
  1>>>pF1KB4334 473 - 473 aa - 473 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9176+/-0.000477; mu= 14.0117+/- 0.029
 mean_var=70.2006+/-14.510, 0's: 0 Z-trim(108.8): 156  B-trim: 0 in 0/53
 Lambda= 0.153075
 statistics sampled from 16686 (16870) to 16686 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.543), E-opt: 0.2 (0.198), width:  16
 Scan time:  8.400

The best scores are:                                      opt bits E(85289)
NP_000805 (OMIM: 137192,612269,617113) gamma-amino ( 473) 3163 708.3 1.1e-203
NP_068712 (OMIM: 137192,612269,617113) gamma-amino ( 473) 2979 667.7 1.9e-191
XP_011519730 (OMIM: 137192,612269,617113) PREDICTE ( 414) 2614 587.1 3.2e-167
NP_001178250 (OMIM: 137192,612269,617113) gamma-am ( 402) 2613 586.8 3.6e-167
NP_001178249 (OMIM: 137192,612269,617113) gamma-am ( 388) 2582 580.0  4e-165
NP_001265560 (OMIM: 137192,612269,617113) gamma-am ( 388) 2582 580.0  4e-165
NP_000804 (OMIM: 600232) gamma-aminobutyric acid r ( 474) 2552 573.4 4.7e-163
NP_000803 (OMIM: 137190,617153) gamma-aminobutyric ( 474) 2461 553.3 5.3e-157
NP_068711 (OMIM: 600232) gamma-aminobutyric acid r ( 512) 2088 470.9 3.6e-132
XP_011529486 (OMIM: 300349) PREDICTED: gamma-amino ( 406) 1218 278.8   2e-74
NP_061028 (OMIM: 300349) gamma-aminobutyric acid r ( 632) 1218 278.8   3e-74
XP_016863474 (OMIM: 137190,617153) PREDICTED: gamm ( 257) 1188 272.1 1.3e-72
XP_016856425 (OMIM: 137163,613060) PREDICTED: gamm ( 687) 1099 252.6 2.6e-66
NP_000806 (OMIM: 137163,613060) gamma-aminobutyric ( 452) 1077 247.6 5.2e-65
XP_011539496 (OMIM: 137163,613060) PREDICTED: gamm ( 465) 1077 247.6 5.3e-65
NP_001243632 (OMIM: 137161) gamma-aminobutyric aci ( 462) 1039 239.2 1.8e-62
NP_002033 (OMIM: 137161) gamma-aminobutyric acid r ( 479) 1039 239.3 1.8e-62
NP_001254511 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1028 236.8 8.2e-62
XP_016866178 (OMIM: 137161) PREDICTED: gamma-amino ( 392) 1028 236.8 8.2e-62
NP_001243633 (OMIM: 137161) gamma-aminobutyric aci ( 392) 1028 236.8 8.2e-62
NP_002034 (OMIM: 137162) gamma-aminobutyric acid r ( 465) 1028 236.8 9.6e-62
NP_055026 (OMIM: 602729) gamma-aminobutyric acid r ( 440) 1009 232.6 1.7e-60
XP_011534015 (OMIM: 137162) PREDICTED: gamma-amino ( 421)  985 227.3 6.3e-59
XP_011543798 (OMIM: 305990) PREDICTED: glycine rec ( 436)  959 221.6 3.5e-57
XP_011543797 (OMIM: 305990) PREDICTED: glycine rec ( 436)  959 221.6 3.5e-57
XP_006724550 (OMIM: 305990) PREDICTED: glycine rec ( 436)  959 221.6 3.5e-57
NP_001112357 (OMIM: 305990) glycine receptor subun ( 452)  959 221.6 3.6e-57
NP_002054 (OMIM: 305990) glycine receptor subunit  ( 452)  959 221.6 3.6e-57
NP_001112358 (OMIM: 305990) glycine receptor subun ( 452)  957 221.1 4.9e-57
XP_016884916 (OMIM: 305990) PREDICTED: glycine rec ( 452)  957 221.1 4.9e-57
NP_001036008 (OMIM: 600421) glycine receptor subun ( 449)  940 217.4 6.6e-56
NP_006520 (OMIM: 600421) glycine receptor subunit  ( 464)  940 217.4 6.8e-56
XP_016864119 (OMIM: 600421) PREDICTED: glycine rec ( 424)  938 216.9 8.5e-56
NP_000162 (OMIM: 138491,149400) glycine receptor s ( 449)  935 216.3 1.4e-55
XP_016864838 (OMIM: 138491,149400) PREDICTED: glyc ( 465)  935 216.3 1.5e-55
NP_001139512 (OMIM: 138491,149400) glycine recepto ( 457)  926 214.3 5.7e-55
NP_000807 (OMIM: 137164,607681,611277) gamma-amino ( 467)  920 213.0 1.5e-54
NP_000815 (OMIM: 138492,614619) glycine receptor s ( 497)  916 212.1 2.9e-54
NP_001159532 (OMIM: 138492,614619) glycine recepto ( 497)  916 212.1 2.9e-54
NP_944494 (OMIM: 137164,607681,611277) gamma-amino ( 475)  915 211.9 3.2e-54
XP_016863475 (OMIM: 137190,617153) PREDICTED: gamm ( 247)  892 206.7   6e-53
NP_775807 (OMIM: 137166) gamma-aminobutyric acid r ( 465)  889 206.1 1.7e-52
XP_011534018 (OMIM: 137162) PREDICTED: gamma-amino ( 366)  886 205.4 2.1e-52
XP_011534019 (OMIM: 137162) PREDICTED: gamma-amino ( 366)  886 205.4 2.1e-52
XP_011534016 (OMIM: 137162) PREDICTED: gamma-amino ( 366)  886 205.4 2.1e-52
XP_011534017 (OMIM: 137162) PREDICTED: gamma-amino ( 366)  886 205.4 2.1e-52
XP_005265929 (OMIM: 602729) PREDICTED: gamma-amino ( 361)  878 203.7 7.2e-52
XP_005268315 (OMIM: 137142) PREDICTED: gamma-amino ( 462)  877 203.5   1e-51
NP_001158509 (OMIM: 137142) gamma-aminobutyric aci ( 462)  877 203.5   1e-51
NP_000801 (OMIM: 137142) gamma-aminobutyric acid r ( 462)  877 203.5   1e-51


>>NP_000805 (OMIM: 137192,612269,617113) gamma-aminobuty  (473 aa)
 initn: 3163 init1: 3163 opt: 3163  Z-score: 3777.5  bits: 708.3 E(85289): 1.1e-203
Smith-Waterman score: 3163; 100.0% identity (100.0% similar) in 473 aa overlap (1-473:1-473)

               10        20        30        40        50        60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
              370       380       390       400       410       420

              430       440       450       460       470   
pF1KB4 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
              430       440       450       460       470   

>>NP_068712 (OMIM: 137192,612269,617113) gamma-aminobuty  (473 aa)
 initn: 2979 init1: 2979 opt: 2979  Z-score: 3557.9  bits: 667.7 E(85289): 1.9e-191
Smith-Waterman score: 2979; 99.8% identity (100.0% similar) in 448 aa overlap (26-473:26-473)

               10        20        30        40        50        60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
                                .::::::::::::::::::::::::::::::::::
NP_068 MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRS
              370       380       390       400       410       420

              430       440       450       460       470   
pF1KB4 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
              430       440       450       460       470   

>>XP_011519730 (OMIM: 137192,612269,617113) PREDICTED: g  (414 aa)
 initn: 2614 init1: 2614 opt: 2614  Z-score: 3123.2  bits: 587.1 E(85289): 3.2e-167
Smith-Waterman score: 2614; 99.2% identity (99.5% similar) in 396 aa overlap (78-473:19-414)

        50        60        70        80        90       100       
pF1KB4 YDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLT
                                     .  :::::::::::::::::::::::::::
XP_011             MQIPSLCDCALLFGSCHIIAKDYTLTMYFQQYWRDKRLAYSGIPLNLT
                           10        20        30        40        

       110       120       130       140       150       160       
pF1KB4 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRR
       50        60        70        80        90       100        

       170       180       190       200       210       220       
pF1KB4 YPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT
      110       120       130       140       150       160        

       230       240       250       260       270       280       
pF1KB4 GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMT
      170       180       190       200       210       220        

       290       300       310       320       330       340       
pF1KB4 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTA
      230       240       250       260       270       280        

       350       360       370       380       390       400       
pF1KB4 KAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSM
      290       300       310       320       330       340        

       410       420       430       440       450       460       
pF1KB4 PREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVY
      350       360       370       380       390       400        

       470   
pF1KB4 WLYYVN
       ::::::
XP_011 WLYYVN
      410    

>>NP_001178250 (OMIM: 137192,612269,617113) gamma-aminob  (402 aa)
 initn: 2613 init1: 2613 opt: 2613  Z-score: 3122.2  bits: 586.8 E(85289): 3.6e-167
Smith-Waterman score: 2613; 100.0% identity (100.0% similar) in 393 aa overlap (81-473:10-402)

               60        70        80        90       100       110
pF1KB4 RLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDN
                                     ::::::::::::::::::::::::::::::
NP_001                      MWATYQTEEDYTLTMYFQQYWRDKRLAYSGIPLNLTLDN
                                    10        20        30         

              120       130       140       150       160       170
pF1KB4 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPL
      40        50        60        70        80        90         

              180       190       200       210       220       230
pF1KB4 DEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAY
     100       110       120       130       140       150         

              240       250       260       270       280       290
pF1KB4 PRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTIN
     160       170       180       190       200       210         

              300       310       320       330       340       350
pF1KB4 THLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAK
     220       230       240       250       260       270         

              360       370       380       390       400       410
pF1KB4 NDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPRE
     280       290       300       310       320       330         

              420       430       440       450       460       470
pF1KB4 GHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLY
     340       350       360       370       380       390         

          
pF1KB4 YVN
       :::
NP_001 YVN
     400  

>>NP_001178249 (OMIM: 137192,612269,617113) gamma-aminob  (388 aa)
 initn: 2582 init1: 2582 opt: 2582  Z-score: 3085.5  bits: 580.0 E(85289): 4e-165
Smith-Waterman score: 2582; 100.0% identity (100.0% similar) in 388 aa overlap (86-473:1-388)

          60        70        80        90       100       110     
pF1KB4 FGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
                                             10        20        30

         120       130       140       150       160       170     
pF1KB4 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
               40        50        60        70        80        90

         180       190       200       210       220       230     
pF1KB4 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
              100       110       120       130       140       150

         240       250       260       270       280       290     
pF1KB4 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
              160       170       180       190       200       210

         300       310       320       330       340       350     
pF1KB4 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
              220       230       240       250       260       270

         360       370       380       390       400       410     
pF1KB4 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
              280       290       300       310       320       330

         420       430       440       450       460       470   
pF1KB4 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
              340       350       360       370       380        

>>NP_001265560 (OMIM: 137192,612269,617113) gamma-aminob  (388 aa)
 initn: 2582 init1: 2582 opt: 2582  Z-score: 3085.5  bits: 580.0 E(85289): 4e-165
Smith-Waterman score: 2582; 100.0% identity (100.0% similar) in 388 aa overlap (86-473:1-388)

          60        70        80        90       100       110     
pF1KB4 FGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
                                     ::::::::::::::::::::::::::::::
NP_001                               MYFQQYWRDKRLAYSGIPLNLTLDNRVADQ
                                             10        20        30

         120       130       140       150       160       170     
pF1KB4 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC
               40        50        60        70        80        90

         180       190       200       210       220       230     
pF1KB4 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL
              100       110       120       130       140       150

         240       250       260       270       280       290     
pF1KB4 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE
              160       170       180       190       200       210

         300       310       320       330       340       350     
pF1KB4 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSK
              220       230       240       250       260       270

         360       370       380       390       400       410     
pF1KB4 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRF
              280       290       300       310       320       330

         420       430       440       450       460       470   
pF1KB4 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
              340       350       360       370       380        

>>NP_000804 (OMIM: 600232) gamma-aminobutyric acid recep  (474 aa)
 initn: 2120 init1: 2120 opt: 2552  Z-score: 3048.3  bits: 573.4 E(85289): 4.7e-163
Smith-Waterman score: 2552; 79.8% identity (92.4% similar) in 475 aa overlap (1-473:1-474)

               10        20        30        40        50        60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
       :: .     :::.: :...:.:: :::::::.:::.::::::.:::::::::::::::::
NP_000 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
               10        20         30        40        50         

               70        80        90       100       110       120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
       : :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_000 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
       ::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_000 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
       ::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_000 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
     300       310       320       330       340       350         

              370         380       390       400       410        
pF1KB4 VDAHGNILLTSLEVHNEM--NEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGD
       .: : ::::..::..:::  .:.  :.:: :.. ...: :.::::: ..::.. ::   .
NP_000 MDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALE
     360       370       380       390       400       410         

      420       430       440       450       460       470   
pF1KB4 RSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       : . .::..::::.::::: :::::::::::::::: :: .::.::.::::::::
NP_000 RHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
     420       430       440       450       460       470    

>>NP_000803 (OMIM: 137190,617153) gamma-aminobutyric aci  (474 aa)
 initn: 2454 init1: 2090 opt: 2461  Z-score: 2939.6  bits: 553.3 E(85289): 5.3e-157
Smith-Waterman score: 2461; 76.9% identity (91.2% similar) in 477 aa overlap (1-473:1-474)

               10        20        30        40        50        60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
       :: . . . .:..: ::....::::.:.:.:.:::.::::::.:::::::::::::::::
NP_000 MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
       : ::: ::.::::::::::::::::::::: :.::::.::::::::::::::::::::::
NP_000 VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
       ::::::::::::: ::. :::::..:::::::::....::..: :.::::::::::::::
NP_000 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
       :::::::::::::: ::::::::::::::::::::::::::::::::::.::::::::::
NP_000 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
       :::::::.:::::::::::::::::::::::::.:::  :: : :  .. :...: : :.
NP_000 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQ--KKGASKQDQSANEKNKLEMNK
              310       320       330         340       350        

                370         380       390       400       410      
pF1KB4 V--DAHGNILLTSLEVHNEMN--EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFL
       :  ::::::::..::..:: .  ::  ...: . .  :.:...:::::    ::..:: :
NP_000 VQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRAL
      360       370       380       390       400       410        

        420       430       440       450       460       470   
pF1KB4 GDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
         ...: .: ..:::.::::.:::::::::.::.:::. ::.::::::.:::::::.
NP_000 DRHGVP-SKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
      420        430       440       450       460       470    

>>NP_068711 (OMIM: 600232) gamma-aminobutyric acid recep  (512 aa)
 initn: 2489 init1: 2040 opt: 2088  Z-score: 2493.9  bits: 470.9 E(85289): 3.6e-132
Smith-Waterman score: 2408; 73.5% identity (85.3% similar) in 505 aa overlap (1-465:1-504)

               10        20        30        40        50        60
pF1KB4 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP
       :: .     :::.: :...:.:: :::::::.:::.::::::.:::::::::::::::::
NP_068 MWRVRKRGYFGIWSFPLIIAAVC-AQSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPP
               10        20         30        40        50         

               70        80        90       100       110       120
pF1KB4 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD
       : :::::::::::::::::::::::::::: ::::::.:. :::::::::::::::::::
NP_068 VAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPD
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB4 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB4 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK
       ::::::::::::::: :.::::: .:::::::::...:....:::.::.::::::::.::
NP_068 SYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLK
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB4 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB4 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNR
       ::::::::::::::::::.::::::.::::::::::::::: :::.:.:.:.. . . :.
NP_068 PYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQKKAAEKAASANNEKMRLDVNK
     300       310       320       330       340       350         

                                                    370         380
pF1KB4 V--------------------------------------DAHGNILLTSLEVHNEM--NE
       .                                      : : ::::..::..:::  .:
NP_068 IFYKDIKQNGTQYRSLWDPTGNLSPTRRTTNYDFSLYTMDPHENILLSTLEIKNEMATSE
     360       370       380       390       400       410         

              390       400       410       420       430       440
pF1KB4 VSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIP
       .  :.:: :.. ...: :.::::: ..::.. ::   .: . .::..::::.::::: ::
NP_068 AVMGLGDPRSTMLAYDASSIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIP
     420       430       440       450       460       470         

              450       460       470   
pF1KB4 DLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN
       :::::::::::::: :: .::.::.        
NP_068 DLTDVNAIDRWSRIFFPVVFSFFNIVYWLYYVN
     480       490       500       510  

>>XP_011529486 (OMIM: 300349) PREDICTED: gamma-aminobuty  (406 aa)
 initn: 1190 init1: 1190 opt: 1218  Z-score: 1457.2  bits: 278.8 E(85289): 2e-74
Smith-Waterman score: 1218; 50.5% identity (83.7% similar) in 325 aa overlap (17-341:43-363)

                             10        20        30        40      
pF1KB4               MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLK
                                     :.. .  : . .:.    . :.. .:..:.
XP_011 LLLIRTWLAEGNYPSPIPKFHFEFSSAVPEVVLNLFNCKNCANE----AVVQKILDRVLS
             20        30        40        50            60        

         50        60        70        80        90       100      
pF1KB4 GYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNL
        ::.::::.::: :: : ..: ..::...::.:::::.::.:.: :.:.::::    :::
XP_011 RYDVRLRPNFGGAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTLNL
       70        80        90       100       110       120        

        110       120       130       140       150       160      
pF1KB4 TLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLR
       ::: :. ..::::: ::::.: .::: :::.::...::::::: ::.:.:::::: .::.
XP_011 TLDYRMHEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLH
      130       140       150       160       170       180        

        170       180       190       200       210       220      
pF1KB4 RYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA
       ..:.:.: :.: .::::::..:: ..:  . .:.  .:....:::... . ..:..: : 
XP_011 KFPMDKQACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFY
      190       200       210       220       230       240        

        230       240       250       260       270       280      
pF1KB4 TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTM
       ::.: :: :.:...:... ...:.: :..: :: ::.:::.:::.:::::..:.:..: .
XP_011 TGSYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLIL
      250       260       270       280       290       300        

        290       300       310       320       330       340      
pF1KB4 TTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKT
       :::..:::. ::.:  .::::.:.. :. ::::.::::...::.:..:::.:: .     
XP_011 TTIDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRP
      310       320       330       340       350       360        

        350       360       370       380       390       400      
pF1KB4 AKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQS
                                                                   
XP_011 RRVIARYRYQQVVVGNVQVGMGQASRNPTLIHSPWRSM                      
      370       380       390       400                            




473 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:48:24 2016 done: Sat Nov  5 05:48:25 2016
 Total Scan time:  8.400 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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