Result of FASTA (omim) for pF1KB4123
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4123, 468 aa
  1>>>pF1KB4123 468 - 468 aa - 468 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.5683+/-0.000554; mu= 11.8820+/- 0.034
 mean_var=172.0384+/-40.379, 0's: 0 Z-trim(112.3): 543  B-trim: 2185 in 2/48
 Lambda= 0.097783
 statistics sampled from 20437 (21143) to 20437 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.248), width:  16
 Scan time:  7.730

The best scores are:                                      opt bits E(85289)
NP_004058 (OMIM: 602857) beta-chimaerin isoform 2  ( 468) 3145 456.9 5.5e-128
NP_001279998 (OMIM: 602857) beta-chimaerin isoform ( 543) 3074 446.9 6.2e-125
XP_011513409 (OMIM: 602857) PREDICTED: beta-chimae ( 494) 3062 445.2 1.9e-124
XP_011513407 (OMIM: 602857) PREDICTED: beta-chimae ( 569) 3062 445.3 2.1e-124
NP_001280001 (OMIM: 602857) beta-chimaerin isoform ( 453) 3058 444.6 2.6e-124
XP_016867211 (OMIM: 602857) PREDICTED: beta-chimae ( 500) 3058 444.6 2.8e-124
XP_016867210 (OMIM: 602857) PREDICTED: beta-chimae ( 575) 3058 444.7 3.1e-124
NP_001279999 (OMIM: 602857) beta-chimaerin isoform ( 481) 3050 443.5  6e-124
XP_011513408 (OMIM: 602857) PREDICTED: beta-chimae ( 556) 3050 443.6 6.6e-124
NP_001280000 (OMIM: 602857) beta-chimaerin isoform ( 433) 2823 411.4 2.5e-114
NP_001813 (OMIM: 118423,604356) N-chimaerin isofor ( 459) 2319 340.3 6.4e-93
NP_001035025 (OMIM: 602857) beta-chimaerin isoform ( 332) 1885 279.0 1.4e-74
NP_001280002 (OMIM: 602857) beta-chimaerin isoform ( 287) 1715 254.9 2.1e-67
NP_001280010 (OMIM: 602857) beta-chimaerin isoform ( 261) 1708 253.9   4e-67
NP_001193531 (OMIM: 118423,604356) N-chimaerin iso ( 334) 1503 225.1 2.4e-58
NP_001020372 (OMIM: 118423,604356) N-chimaerin iso ( 433) 1409 211.9 2.7e-54
NP_001280005 (OMIM: 602857) beta-chimaerin isoform ( 274) 1065 163.2 8.3e-40
NP_001280009 (OMIM: 602857) beta-chimaerin isoform ( 286) 1007 155.0 2.5e-37
NP_001280008 (OMIM: 602857) beta-chimaerin isoform ( 197)  994 153.0 6.9e-37
NP_001280004 (OMIM: 602857) beta-chimaerin isoform ( 241)  837 130.9 3.7e-30
NP_001280006 (OMIM: 602857) beta-chimaerin isoform ( 260)  824 129.2 1.4e-29
NP_001280007 (OMIM: 602857) beta-chimaerin isoform ( 228)  589 95.9 1.2e-19
NP_001123537 (OMIM: 602129,609753) unconventional  (2022)  463 79.3 1.1e-13
NP_004136 (OMIM: 602129,609753) unconventional myo (2157)  463 79.3 1.1e-13
XP_011519925 (OMIM: 604875) PREDICTED: unconventio (1737)  458 78.5 1.6e-13
XP_016877719 (OMIM: 604875) PREDICTED: unconventio (2547)  458 78.7 2.1e-13
NP_008832 (OMIM: 604875) unconventional myosin-IXa (2548)  458 78.7 2.1e-13
XP_011519924 (OMIM: 604875) PREDICTED: unconventio (2566)  458 78.7 2.1e-13
XP_016877718 (OMIM: 604875) PREDICTED: unconventio (2566)  458 78.7 2.1e-13
XP_011519923 (OMIM: 604875) PREDICTED: unconventio (2598)  458 78.7 2.1e-13
XP_011519922 (OMIM: 604875) PREDICTED: unconventio (2618)  458 78.7 2.1e-13
XP_006720602 (OMIM: 604875) PREDICTED: unconventio (2619)  458 78.7 2.1e-13
XP_016877717 (OMIM: 604875) PREDICTED: unconventio (2619)  458 78.7 2.1e-13
XP_011519921 (OMIM: 604875) PREDICTED: unconventio (2619)  458 78.7 2.1e-13
XP_011519920 (OMIM: 604875) PREDICTED: unconventio (2620)  458 78.7 2.1e-13
XP_011519919 (OMIM: 604875) PREDICTED: unconventio (2637)  458 78.7 2.1e-13
XP_011519918 (OMIM: 604875) PREDICTED: unconventio (2638)  458 78.7 2.1e-13
XP_011519915 (OMIM: 604875) PREDICTED: unconventio (2638)  458 78.7 2.1e-13
XP_011519916 (OMIM: 604875) PREDICTED: unconventio (2638)  458 78.7 2.1e-13
XP_011519917 (OMIM: 604875) PREDICTED: unconventio (2638)  458 78.7 2.1e-13
XP_011509785 (OMIM: 610578) PREDICTED: rho GTPase- ( 397)  442 75.5   3e-13
XP_016859989 (OMIM: 610578) PREDICTED: rho GTPase- ( 432)  442 75.5 3.2e-13
NP_954976 (OMIM: 610591) rho GTPase-activating pro ( 548)  443 75.8 3.4e-13
XP_011509781 (OMIM: 610578) PREDICTED: rho GTPase- ( 475)  442 75.6 3.4e-13
NP_060930 (OMIM: 610578) rho GTPase-activating pro ( 475)  442 75.6 3.4e-13
XP_016859988 (OMIM: 610578) PREDICTED: rho GTPase- ( 475)  442 75.6 3.4e-13
XP_011522776 (OMIM: 610591) PREDICTED: rho GTPase- ( 581)  443 75.8 3.5e-13
XP_005257185 (OMIM: 610591) PREDICTED: rho GTPase- ( 667)  443 75.9 3.8e-13
XP_016879801 (OMIM: 610591) PREDICTED: rho GTPase- ( 689)  443 75.9 3.9e-13
XP_011522774 (OMIM: 610591) PREDICTED: rho GTPase- ( 722)  443 75.9   4e-13


>>NP_004058 (OMIM: 602857) beta-chimaerin isoform 2 [Hom  (468 aa)
 initn: 3145 init1: 3145 opt: 3145  Z-score: 2418.8  bits: 456.9 E(85289): 5.5e-128
Smith-Waterman score: 3145; 100.0% identity (100.0% similar) in 468 aa overlap (1-468:1-468)

               10        20        30        40        50        60
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB4 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
              370       380       390       400       410       420

              430       440       450       460        
pF1KB4 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
              430       440       450       460        

>>NP_001279998 (OMIM: 602857) beta-chimaerin isoform 3 [  (543 aa)
 initn: 3074 init1: 3074 opt: 3074  Z-score: 2363.9  bits: 446.9 E(85289): 6.2e-125
Smith-Waterman score: 3074; 99.6% identity (99.8% similar) in 457 aa overlap (12-468:87-543)

                                  10        20        30        40 
pF1KB4                    MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPK
                                     :: .::::::::::::::::::::::::::
NP_001 LASPGFTFGKRVVFDSHCLKRQHTFADGLHSSCTSDAEEYQPPIWKSYLYQLQQEAPRPK
         60        70        80        90       100       110      

              50        60        70        80        90       100 
pF1KB4 RIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQ
        120       130       140       150       160       170      

             110       120       130       140       150       160 
pF1KB4 TLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATL
        180       190       200       210       220       230      

             170       180       190       200       210       220 
pF1KB4 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHT
        240       250       260       270       280       290      

             230       240       250       260       270       280 
pF1KB4 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTT
        300       310       320       330       340       350      

             290       300       310       320       330       340 
pF1KB4 LVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANV
        360       370       380       390       400       410      

             350       360       370       380       390       400 
pF1KB4 YPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYE
        420       430       440       450       460       470      

             410       420       430       440       450       460 
pF1KB4 TLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILI
        480       490       500       510       520       530      

              
pF1KB4 ENEDVLF
       :::::::
NP_001 ENEDVLF
        540   

>>XP_011513409 (OMIM: 602857) PREDICTED: beta-chimaerin   (494 aa)
 initn: 3060 init1: 3060 opt: 3062  Z-score: 2355.2  bits: 445.2 E(85289): 1.9e-124
Smith-Waterman score: 3083; 94.7% identity (94.7% similar) in 494 aa overlap (1-468:1-494)

               10                                  20        30    
pF1KB4 MAASSNSSLSGSSVSS--------------------------DAEEYQPPIWKSYLYQLQ
       ::::::::::::::::                          ::::::::::::::::::
XP_011 MAASSNSSLSGSSVSSVYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYLYQLQ
               10        20        30        40        50        60

           40        50        60        70        80        90    
pF1KB4 QEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTL
               70        80        90       100       110       120

          100       110       120       130       140       150    
pF1KB4 ALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE
              130       140       150       160       170       180

          160       170       180       190       200       210    
pF1KB4 HIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKT
              190       200       210       220       230       240

          220       230       240       250       260       270    
pF1KB4 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKV
              250       260       270       280       290       300

          280       290       300       310       320       330    
pF1KB4 YCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEK
              310       320       330       340       350       360

          340       350       360       370       380       390    
pF1KB4 ADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLML
              370       380       390       400       410       420

          400       410       420       430       440       450    
pF1KB4 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK
              430       440       450       460       470       480

          460        
pF1KB4 LIVQILIENEDVLF
       ::::::::::::::
XP_011 LIVQILIENEDVLF
              490    

>>XP_011513407 (OMIM: 602857) PREDICTED: beta-chimaerin   (569 aa)
 initn: 3060 init1: 3060 opt: 3062  Z-score: 2354.5  bits: 445.3 E(85289): 2.1e-124
Smith-Waterman score: 3062; 97.0% identity (98.5% similar) in 468 aa overlap (1-468:102-569)

                                             10        20        30
pF1KB4                               MAASSNSSLSGSSVSSDAEEYQPPIWKSYL
                                     .  : ... : .  ..::::::::::::::
XP_011 SHCLKRQHTFADGLHSSCTSIYSEPRSPRELPKSPDTQASLQFPQTDAEEYQPPIWKSYL
              80        90       100       110       120       130 

               40        50        60        70        80        90
pF1KB4 YQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPG
             140       150       160       170       180       190 

              100       110       120       130       140       150
pF1KB4 CYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTN
             200       210       220       230       240       250 

              160       170       180       190       200       210
pF1KB4 PIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFN
             260       270       280       290       300       310 

              220       230       240       250       260       270
pF1KB4 YEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKR
             320       330       340       350       360       370 

              280       290       300       310       320       330
pF1KB4 IKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDR
             380       390       400       410       420       430 

              340       350       360       370       380       390
pF1KB4 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHE
             440       450       460       470       480       490 

              400       410       420       430       440       450
pF1KB4 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDM
             500       510       520       530       540       550 

              460        
pF1KB4 RYQKLIVQILIENEDVLF
       ::::::::::::::::::
XP_011 RYQKLIVQILIENEDVLF
             560         

>>NP_001280001 (OMIM: 602857) beta-chimaerin isoform 6 [  (453 aa)
 initn: 3058 init1: 3058 opt: 3058  Z-score: 2352.6  bits: 444.6 E(85289): 2.6e-124
Smith-Waterman score: 3058; 100.0% identity (100.0% similar) in 452 aa overlap (17-468:2-453)

               10        20        30        40        50        60
pF1KB4 MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
                       ::::::::::::::::::::::::::::::::::::::::::::
NP_001                MDAEEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREF
                              10        20        30        40     

               70        80        90       100       110       120
pF1KB4 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRF
          50        60        70        80        90       100     

              130       140       150       160       170       180
pF1KB4 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKT
         110       120       130       140       150       160     

              190       200       210       220       230       240
pF1KB4 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIA
         170       180       190       200       210       220     

              250       260       270       280       290       300
pF1KB4 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIRE
         230       240       250       260       270       280     

              310       320       330       340       350       360
pF1KB4 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLP
         290       300       310       320       330       340     

              370       380       390       400       410       420
pF1KB4 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDN
         350       360       370       380       390       400     

              430       440       450       460        
pF1KB4 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
       ::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF
         410       420       430       440       450   

>>XP_016867211 (OMIM: 602857) PREDICTED: beta-chimaerin   (500 aa)
 initn: 3131 init1: 3058 opt: 3058  Z-score: 2352.1  bits: 444.6 E(85289): 2.8e-124
Smith-Waterman score: 3071; 93.6% identity (93.6% similar) in 500 aa overlap (1-468:1-500)

               10                                        20        
pF1KB4 MAASSNSSLSGSSVSS--------------------------------DAEEYQPPIWKS
       ::::::::::::::::                                ::::::::::::
XP_016 MAASSNSSLSGSSVSSVYSEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKS
               10        20        30        40        50        60

       30        40        50        60        70        80        
pF1KB4 YLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQ
               70        80        90       100       110       120

       90       100       110       120       130       140        
pF1KB4 PGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMT
              130       140       150       160       170       180

      150       160       170       180       190       200        
pF1KB4 TNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNH
              190       200       210       220       230       240

      210       220       230       240       250       260        
pF1KB4 FNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDL
              250       260       270       280       290       300

      270       280       290       300       310       320        
pF1KB4 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAF
              310       320       330       340       350       360

      330       340       350       360       370       380        
pF1KB4 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAV
              370       380       390       400       410       420

      390       400       410       420       430       440        
pF1KB4 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLH
              430       440       450       460       470       480

      450       460        
pF1KB4 DMRYQKLIVQILIENEDVLF
       ::::::::::::::::::::
XP_016 DMRYQKLIVQILIENEDVLF
              490       500

>>XP_016867210 (OMIM: 602857) PREDICTED: beta-chimaerin   (575 aa)
 initn: 3058 init1: 3058 opt: 3058  Z-score: 2351.4  bits: 444.7 E(85289): 3.1e-124
Smith-Waterman score: 3058; 100.0% identity (100.0% similar) in 452 aa overlap (17-468:124-575)

                             10        20        30        40      
pF1KB4               MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
                                     ::::::::::::::::::::::::::::::
XP_016 SEPRSPRELPKSPDTQASLQFPQTDYKLLEDAEEYQPPIWKSYLYQLQQEAPRPKRIICP
           100       110       120       130       140       150   

         50        60        70        80        90       100      
pF1KB4 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYR
           160       170       180       190       200       210   

        110       120       130       140       150       160      
pF1KB4 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKV
           220       230       240       250       260       270   

        170       180       190       200       210       220      
pF1KB4 SRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPH
           280       290       300       310       320       330   

        230       240       250       260       270       280      
pF1KB4 WCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WCEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAH
           340       350       360       370       380       390   

        290       300       310       320       330       340      
pF1KB4 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDIN
           400       410       420       430       440       450   

        350       360       370       380       390       400      
pF1KB4 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYL
           460       470       480       490       500       510   

        410       420       430       440       450       460      
pF1KB4 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDV
           520       530       540       550       560       570   

         
pF1KB4 LF
       ::
XP_016 LF
         

>>NP_001279999 (OMIM: 602857) beta-chimaerin isoform 4 [  (481 aa)
 initn: 3050 init1: 3050 opt: 3050  Z-score: 2346.2  bits: 443.5 E(85289): 6e-124
Smith-Waterman score: 3098; 97.1% identity (97.1% similar) in 481 aa overlap (1-468:1-481)

               10                     20        30        40       
pF1KB4 MAASSNSSLSGSSVSS-------------DAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
       ::::::::::::::::              ::::::::::::::::::::::::::::::
NP_001 MAASSNSSLSGSSVSSVYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
               10        20        30        40        50        60

        50        60        70        80        90       100       
pF1KB4 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
               70        80        90       100       110       120

       110       120       130       140       150       160       
pF1KB4 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
              130       140       150       160       170       180

       170       180       190       200       210       220       
pF1KB4 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
              190       200       210       220       230       240

       230       240       250       260       270       280       
pF1KB4 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
              250       260       270       280       290       300

       290       300       310       320       330       340       
pF1KB4 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
              310       320       330       340       350       360

       350       360       370       380       390       400       
pF1KB4 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
              370       380       390       400       410       420

       410       420       430       440       450       460       
pF1KB4 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
              430       440       450       460       470       480

        
pF1KB4 F
       :
NP_001 F
        

>>XP_011513408 (OMIM: 602857) PREDICTED: beta-chimaerin   (556 aa)
 initn: 3050 init1: 3050 opt: 3050  Z-score: 2345.5  bits: 443.6 E(85289): 6.6e-124
Smith-Waterman score: 3050; 100.0% identity (100.0% similar) in 451 aa overlap (18-468:106-556)

                            10        20        30        40       
pF1KB4              MAASSNSSLSGSSVSSDAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
                                     ::::::::::::::::::::::::::::::
XP_011 KRQHTFADGLHSSCTSIYSEPRSPRELPKYAEEYQPPIWKSYLYQLQQEAPRPKRIICPR
          80        90       100       110       120       130     

        50        60        70        80        90       100       
pF1KB4 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVENRPKYYGREFHGIISREQADELLGGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL
         140       150       160       170       180       190     

       110       120       130       140       150       160       
pF1KB4 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHDGKHFVGEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYEHIGYATLLREKVS
         200       210       220       230       240       250     

       170       180       190       200       210       220       
pF1KB4 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRLSRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHNDNHFNYEKTHNFKVHTFRGPHW
         260       270       280       290       300       310     

       230       240       250       260       270       280       
pF1KB4 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEYCANFMWGLIAQGVRCSDCGLNVHKQCSKHVPNDCQPDLKRIKKVYCCDLTTLVKAHN
         320       330       340       350       360       370     

       290       300       310       320       330       340       
pF1KB4 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINI
         380       390       400       410       420       430     

       350       360       370       380       390       400       
pF1KB4 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRYLM
         440       450       460       470       480       490     

       410       420       430       440       450       460       
pF1KB4 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVL
         500       510       520       530       540       550     

        
pF1KB4 F
       :
XP_011 F
        

>>NP_001280000 (OMIM: 602857) beta-chimaerin isoform 5 [  (433 aa)
 initn: 2823 init1: 2823 opt: 2823  Z-score: 2173.7  bits: 411.4 E(85289): 2.5e-114
Smith-Waterman score: 2823; 100.0% identity (100.0% similar) in 420 aa overlap (49-468:14-433)

       20        30        40        50        60        70        
pF1KB4 EEYQPPIWKSYLYQLQQEAPRPKRIICPREVENRPKYYGREFHGIISREQADELLGGVEG
                                     ::::::::::::::::::::::::::::::
NP_001                  MLKNTSLLYGNHTVENRPKYYGREFHGIISREQADELLGGVEG
                                10        20        30        40   

       80        90       100       110       120       130        
pF1KB4 AYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIET
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFVGEKRFESIHDLVTDGLITLYIET
            50        60        70        80        90       100   

      140       150       160       170       180       190        
pF1KB4 KAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAAEYISKMTTNPIYEHIGYATLLREKVSRRLSRSKNEPRKTNVTHEEHTAVEKISSLVR
           110       120       130       140       150       160   

      200       210       220       230       240       250        
pF1KB4 RAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAALTHNDNHFNYEKTHNFKVHTFRGPHWCEYCANFMWGLIAQGVRCSDCGLNVHKQCSK
           170       180       190       200       210       220   

      260       270       280       290       300       310        
pF1KB4 HVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVPNDCQPDLKRIKKVYCCDLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFT
           230       240       250       260       270       280   

      320       330       340       350       360       370        
pF1KB4 EHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHIEDVKMAFDRDGEKADISANVYPDINIITGALKLYFRDLPIPVITYDTYSKFIDAAKI
           290       300       310       320       330       340   

      380       390       400       410       420       430        
pF1KB4 SNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNADERLEAVHEVLMLLPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRP
           350       360       370       380       390       400   

      440       450       460        
pF1KB4 PEDSTLTTLHDMRYQKLIVQILIENEDVLF
       ::::::::::::::::::::::::::::::
NP_001 PEDSTLTTLHDMRYQKLIVQILIENEDVLF
           410       420       430   




468 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:39:22 2016 done: Sat Nov  5 05:39:23 2016
 Total Scan time:  7.730 Total Display time:  0.070

Function used was FASTA [36.3.4 Apr, 2011]
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