Result of FASTA (ccds) for pF1KB3969
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB3969, 192 aa
  1>>>pF1KB3969 192 - 192 aa - 192 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5476+/-0.000903; mu= 12.2390+/- 0.055
 mean_var=78.1209+/-15.810, 0's: 0 Z-trim(107.8): 168  B-trim: 279 in 1/49
 Lambda= 0.145108
 statistics sampled from 9597 (9786) to 9597 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.301), width:  16
 Scan time:  2.040

The best scores are:                                      opt bits E(32554)
CCDS33717.1 NKIRAS1 gene_id:28512|Hs108|chr3       ( 192) 1244 269.5   9e-73
CCDS11415.1 NKIRAS2 gene_id:28511|Hs108|chr17      ( 191)  907 198.9 1.5e-51
CCDS45679.1 NKIRAS2 gene_id:28511|Hs108|chr17      ( 135)  369 86.2 9.4e-18
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12           ( 188)  297 71.2 4.2e-13
CCDS45680.1 NKIRAS2 gene_id:28511|Hs108|chr17      (  97)  282 67.9 2.2e-12
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12           ( 189)  285 68.7 2.4e-12
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11         ( 204)  285 68.7 2.6e-12
CCDS877.1 NRAS gene_id:4893|Hs108|chr1             ( 189)  284 68.5 2.8e-12
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11           ( 189)  282 68.1 3.7e-12
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12       ( 183)  270 65.6 2.1e-11
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19          ( 218)  267 65.0 3.7e-11
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11           ( 170)  261 63.7 7.2e-11
CCDS5460.1 RALA gene_id:5898|Hs108|chr7            ( 206)  260 63.5 9.7e-11
CCDS2131.1 RALB gene_id:5899|Hs108|chr2            ( 206)  260 63.5 9.7e-11


>>CCDS33717.1 NKIRAS1 gene_id:28512|Hs108|chr3            (192 aa)
 initn: 1244 init1: 1244 opt: 1244  Z-score: 1420.0  bits: 269.5 E(32554): 9e-73
Smith-Waterman score: 1244; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
              130       140       150       160       170       180

              190  
pF1KB3 GRKNKGNSNSEN
       ::::::::::::
CCDS33 GRKNKGNSNSEN
              190  

>>CCDS11415.1 NKIRAS2 gene_id:28511|Hs108|chr17           (191 aa)
 initn: 923 init1: 885 opt: 907  Z-score: 1038.7  bits: 198.9 E(32554): 1.5e-51
Smith-Waterman score: 907; 71.4% identity (93.1% similar) in 189 aa overlap (1-189:1-188)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
       :::.:::::::  :::::.::::::::::..: :  ::.::.:..:.::::::.::...:
CCDS11 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       :::::..:.:::.: :: .::.:::::... ::::::::::::::: ::::::.::::::
CCDS11 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.::: 
CCDS11 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
              130       140       150       160       170          

              190  
pF1KB3 GRKNKGNSNSEN
       .:::::...   
CCDS11 SRKNKGSGSLDG
     180       190 

>>CCDS45679.1 NKIRAS2 gene_id:28511|Hs108|chr17           (135 aa)
 initn: 625 init1: 336 opt: 369  Z-score: 432.2  bits: 86.2 E(32554): 9.4e-18
Smith-Waterman score: 521; 50.3% identity (65.6% similar) in 189 aa overlap (1-189:1-132)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
       :::.:::::::  :::::.::::::::::..: :  ::.::.:..:.::::::.::    
CCDS45 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ----
               10        20        30        40        50          

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
                                                           :.::::::
CCDS45 ----------------------------------------------------VTIVVLGN
                                                             60    

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::.:::.:: .:::.:::::::.::::.:.::..:.:::. ::::..::::::.::: 
CCDS45 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL-
           70        80        90       100       110       120    

              190  
pF1KB3 GRKNKGNSNSEN
       .:::::...   
CCDS45 SRKNKGSGSLDG
           130     

>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12                (188 aa)
 initn: 221 init1: 161 opt: 297  Z-score: 348.7  bits: 71.2 E(32554): 4.2e-13
Smith-Waterman score: 297; 32.3% identity (62.9% similar) in 186 aa overlap (6-191:5-184)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
            :.:: :  .:::.:.  ::.  :: .   :  :.:: :  .:  : :    : . 
CCDS87  MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
                10        20         30         40         50      

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       :: : .:   .  .:.  ..::. :...:: .::. ..  ...: . ::...: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGN
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::  .: ::.. ::. :.:  . . :...  :. . . :  :. .. . . : :    
CCDS87 KCDLP-SRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMS--KD
        120        130       140       150       160       170     

              190     
pF1KB3 GRKNKGNSNSEN   
       :.:.: .:...    
CCDS87 GKKKKKKSKTKCVIM
           180        

>>CCDS45680.1 NKIRAS2 gene_id:28511|Hs108|chr17           (97 aa)
 initn: 282 init1: 282 opt: 282  Z-score: 335.9  bits: 67.9 E(32554): 2.2e-12
Smith-Waterman score: 282; 71.9% identity (91.2% similar) in 57 aa overlap (1-57:1-57)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
       :::.:::::::  :::::.::::::::::..: :  ::.::.:..:.::::::.::.   
CCDS45 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
                                                                   
CCDS45 LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV                       
               70        80        90                              

>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12                (189 aa)
 initn: 221 init1: 161 opt: 285  Z-score: 335.1  bits: 68.7 E(32554): 2.4e-12
Smith-Waterman score: 285; 33.1% identity (62.7% similar) in 169 aa overlap (6-174:5-169)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
            :.:: :  .:::.:.  ::.  :: .   :  :.:: :  .:  : :    : . 
CCDS87  MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
                10        20         30         40         50      

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       :: : .:   .  .:.  ..::. :...:: .::. ..  ...: . ::...: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGN
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::  .: ::.. ::. :.:  . . :...  :. . . :  :. .. : . :      
CCDS87 KCDLP-SRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEE
        120        130       140       150       160       170     

              190    
pF1KB3 GRKNKGNSNSEN  
                     
CCDS87 KTPGCVKIKKCIIM
         180         

>>CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11              (204 aa)
 initn: 232 init1: 209 opt: 285  Z-score: 334.6  bits: 68.7 E(32554): 2.6e-12
Smith-Waterman score: 285; 32.2% identity (62.3% similar) in 183 aa overlap (6-185:16-194)

                         10        20        30        40          
pF1KB3           MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMAS-VET
                      ..:: :  .:::.:.  :.. .  .  ..   :.:: :  . :  
CCDS78 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDP--TIEDSYTKQCVID
               10        20        30        40          50        

      50        60        70        80        90       100         
pF1KB3 DRGVKEQLHLYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKD
       ::...  : . :: : .:   . ..:.  ..::.::.::..  ::...  ....: . ::
CCDS78 DRAAR--LDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKD
       60          70        80        90       100       110      

     110       120       130       140       150       160         
pF1KB3 KKEVAIVVLGNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLS
       . :  ....::: ::..::::  : .:: :.. ::   :...  : .. . :  :.  . 
CCDS78 RDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIR
        120       130       140       150       160       170      

       170       180       190     
pF1KB3 --QPQSKSSFPLPGRKNKGNSNSEN   
         : :     : : ::.:          
CCDS78 KFQEQECPPSPEPTRKEKDKKGCHCVIF
        180       190       200    

>>CCDS877.1 NRAS gene_id:4893|Hs108|chr1                  (189 aa)
 initn: 221 init1: 162 opt: 284  Z-score: 333.9  bits: 68.5 E(32554): 2.8e-12
Smith-Waterman score: 284; 33.7% identity (61.5% similar) in 169 aa overlap (6-174:5-169)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
            :.:: :  .:::.:.  ::.  :: .   :  :.:: :  .:  : :    : . 
CCDS87  MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
                10        20         30         40         50      

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       :: : .:   .  .:.  ..::. :...:: .::  ..: ...: . ::. .: .:..::
CCDS87 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGN
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::   : ::.. :.. :::  . . :...  :. . . :  :. .. : . :      
CCDS87 KCDLPT-RTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSD
        120        130       140       150       160       170     

              190    
pF1KB3 GRKNKGNSNSEN  
                     
CCDS87 DGTQGCMGLPCVVM
         180         

>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11                (189 aa)
 initn: 195 init1: 161 opt: 282  Z-score: 331.7  bits: 68.1 E(32554): 3.7e-12
Smith-Waterman score: 282; 31.5% identity (61.3% similar) in 181 aa overlap (6-186:5-180)

               10        20        30        40        50        60
pF1KB3 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY
            :.:: :  .:::.:.  ::.  :: .   :  :.:: :  .:  : :    : . 
CCDS76  MTEYKLVVVGAGGVGKSALTIQLIQ-NHFVDEYD-PTIEDSYRKQVVID-GETCLLDIL
                10        20         30         40         50      

               70        80        90       100       110       120
pF1KB3 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN
       :: : .:   .  .:.  ..::. :...:: .::. ..  ...: . ::. .: .:..::
CCDS76 DTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGN
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB3 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP
       : ::.  : :... ::. :.:  .   :...  :. . . :  :. .. : . ..  : :
CCDS76 KCDLAA-RTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNP-P
        120        130       140       150       160       170     

              190     
pF1KB3 GRKNKGNSNSEN   
        ... :         
CCDS76 DESGPGCMSCKCVLS
          180         

>>CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12            (183 aa)
 initn: 264 init1: 210 opt: 270  Z-score: 318.3  bits: 65.6 E(32554): 2.1e-11
Smith-Waterman score: 270; 32.7% identity (64.8% similar) in 165 aa overlap (6-170:8-169)

                 10        20        30        40        50        
pF1KB3   MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLH
              :::. :   ::::.. .:.. :. . :..   :.:..:   :   .  . .::
CCDS87 MPLVRYRKVVILGYRCVGKTSLAHQFVEGEFSEGYDP--TVENTYSKIVTLGKD-EFHLH
               10        20        30          40        50        

       60        70        80        90       100       110        
pF1KB3 LYDTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVL
       : :: : .:   ::  ..  . :.::::::..:.::: .: : ... . . : .: .:..
CCDS87 LVDTAGQDEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLV
        60        70        80        90       100       110       

      120       130       140       150       160       170        
pF1KB3 GNKIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFP
       ::: ::: .:.:.:  ... :.:  . . : .. . .     :: . .....        
CCDS87 GNKADLSPEREVQAVEGKKLAESWGATFMESSARENQLTQGIFTKVIQEIARVENSYGQE
       120       130       140       150       160       170       

      180       190  
pF1KB3 LPGRKNKGNSNSEN
                     
CCDS87 RRCHLM        
       180           




192 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:29:29 2016 done: Sat Nov  5 05:29:30 2016
 Total Scan time:  2.040 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]
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