Result of FASTA (omim) for pF1KE0841
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0841, 342 aa
  1>>>pF1KE0841 342 - 342 aa - 342 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.6109+/-0.0005; mu= 20.3629+/- 0.031
 mean_var=102.4452+/-26.908, 0's: 0 Z-trim(109.3): 541  B-trim: 2039 in 2/48
 Lambda= 0.126715
 statistics sampled from 16714 (17480) to 16714 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.205), width:  16
 Scan time:  7.500

The best scores are:                                      opt bits E(85289)
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 2255 423.6 3.1e-118
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 1880 355.0 1.4e-97
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 1625 308.4 1.5e-83
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 1019 197.6 3.3e-50
NP_612200 (OMIM: 609333) trace amine-associated re ( 339)  920 179.5 9.2e-45
NP_001028252 (OMIM: 604849) trace amine-associated ( 351)  851 166.9 5.9e-41
NP_055441 (OMIM: 604849) trace amine-associated re ( 306)  800 157.5 3.5e-38
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317)  407 85.7 1.5e-16
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360)  405 85.4 2.1e-16
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378)  405 85.4 2.1e-16
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387)  405 85.4 2.2e-16
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388)  405 85.4 2.2e-16
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324)  404 85.1 2.2e-16
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411)  405 85.5 2.2e-16
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428)  405 85.5 2.3e-16
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308)  403 84.9 2.4e-16
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342)  403 85.0 2.6e-16
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370)  403 85.0 2.7e-16
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372)  403 85.0 2.7e-16
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429)  403 85.1   3e-16
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429)  403 85.1   3e-16
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455)  403 85.2 3.1e-16
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466)  403 85.2 3.1e-16
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  403 85.2 3.2e-16
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475)  403 85.2 3.2e-16
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  403 85.2 3.2e-16
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  403 85.2 3.2e-16
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  383 81.4 3.4e-15
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  383 81.4 3.4e-15
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  383 81.4 3.6e-15
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  383 81.5 3.7e-15
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  383 81.5 3.7e-15
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  383 81.5 3.7e-15
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  383 81.5 3.7e-15
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  383 81.5 3.7e-15
NP_057624 (OMIM: 605569) probable G-protein couple ( 423)  377 80.4 7.9e-15
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390)  375 79.9 9.8e-15
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465)  375 80.1 1.1e-14
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478)  374 79.9 1.2e-14
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin  ( 528)  374 79.9 1.3e-14
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377)  370 79.0 1.8e-14
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412)  369 78.9 2.2e-14
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412)  369 78.9 2.2e-14
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412)  369 78.9 2.2e-14
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412)  369 78.9 2.2e-14
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412)  369 78.9 2.2e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413)  369 78.9 2.2e-14
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450)  367 78.6 2.9e-14
XP_005264808 (OMIM: 182134) PREDICTED: 5-hydroxytr ( 366)  362 77.5 4.9e-14
NP_001309138 (OMIM: 182134) 5-hydroxytryptamine re ( 366)  362 77.5 4.9e-14


>>NP_444508 (OMIM: 606927) trace amine-associated recept  (342 aa)
 initn: 2255 init1: 2255 opt: 2255  Z-score: 2243.6  bits: 423.6 E(85289): 3.1e-118
Smith-Waterman score: 2255; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:1-342)

               10        20        30        40        50        60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 SALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 SESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAY
              250       260       270       280       290       300

              310       320       330       340  
pF1KE0 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
       ::::::::::::::::::::::::::::::::::::::::::
NP_444 YNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
              310       320       330       340  

>>NP_778237 (OMIM: 608923) trace amine-associated recept  (345 aa)
 initn: 1890 init1: 1870 opt: 1880  Z-score: 1873.0  bits: 355.0 E(85289): 1.4e-97
Smith-Waterman score: 1880; 79.6% identity (92.7% similar) in 343 aa overlap (1-342:1-343)

                10        20        30        40        50         
pF1KE0 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
       :.:: :  : ::::: .:::::.. :.::::::::: .:.::..:::::::::: :.:::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE0 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
       ::::::::::.::::::::::::::: :::::::::::::: .:::.:.::::::::::.
NP_778 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE0 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
       .::::: :::::.::::::: :::::::::::::::::::: :::::::::: :::::::
NP_778 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KE0 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
        .::::.:::: .:.:.::: ::: :::::..:::::..:::.:..:: :::.:.::.::
NP_778 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE0 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
       :::::: :::.:::::::::::::.::.::::::..: ::::::::.::: ::::::: :
NP_778 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
              250       260       270       280       290       300

     300       310       320       330       340    
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE  
       :::::::::::::::::::::::.:..:.::: ::.:..:: :  
NP_778 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
              310       320       330       340     

>>NP_778227 (OMIM: 608282) trace amine-associated recept  (348 aa)
 initn: 1657 init1: 1596 opt: 1625  Z-score: 1621.1  bits: 308.4 E(85289): 1.5e-83
Smith-Waterman score: 1625; 67.6% identity (89.8% similar) in 343 aa overlap (1-342:1-343)

                10        20        30        40        50         
pF1KE0 MTSNFSQP-VVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
       :..::::  .:.:::..:: :::.:::::: : :::....::..::.::::::: ..:::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KE0 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
       ::::.::::::::::::::::::::: :: ::.:::::::: ..: .:.: :..::..:.
NP_778 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KE0 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
       .::: : .::::.:::::.: :::::::::::: .::.. .::: ..::::.:..:.:::
NP_778 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KE0 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
       : ::.::::::  ..:.:::. :::::::...:...::::::.::.:: :::.:.:...:
NP_778 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
              190       200       210       220       230       240

     240       250       260       270       280       290         
pF1KE0 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
       :::::: ::::::::::::::... ::..::::: :: .:::.:.:.:: :.:::  : .
NP_778 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
              250       260       270       280       290       300

     300       310       320       330       340       
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE     
       ::::::::::::.:: :: ::::::.:: ::...::: .:: :     
NP_778 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
              310       320       330       340        

>>NP_003958 (OMIM: 607405) trace amine-associated recept  (337 aa)
 initn: 1063 init1: 690 opt: 1019  Z-score: 1022.5  bits: 197.6 E(85289): 3.3e-50
Smith-Waterman score: 1019; 44.1% identity (73.7% similar) in 331 aa overlap (12-342:16-337)

                   10        20        30        40        50      
pF1KE0     MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSV
                      .::. ::::: .: .. : ....: : . : :. :.::..:  .:
NP_003 MRAVFIQGAEEHPAAFCYQ-VNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAV
               10         20        30        40        50         

         60        70        80        90       100       110      
pF1KE0 LHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCY
        .:: ::.:::::. ::: ::...:. :. .: .:.:::::.::  .: ::.  :. :: 
NP_003 SYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCL
      60        70        80        90       100       110         

        120       130       140       150       160       170      
pF1KE0 SSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGL
       .:..::::: :::. .. :::.: .:::: :.   : ..: .: .:..  .:: : .  :
NP_003 TSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRL
     120       130       140       150       160       170         

        180       190       200       210       220       230      
pF1KE0 EELVSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSK
        . .  . :::.::..... :  ..: :::.: :.:: :: :::..: .:: .: : :..
NP_003 SQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQITTLSKS
     180       190       200       210       220       230         

        240       250       260       270       280       290      
pF1KE0 VESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICC
       . ..        ::.:::::::::..:  ... :::.:.: ..:... :.::  ...:  
NP_003 LAGA--------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI
     240               250       260       270       280       290 

        300       310       320       330       340  
pF1KE0 WSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE
       : ::.::: ::.::.. : :::::.:: ::  :.. .. :..:. :
NP_003 WFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE
             300       310       320       330       

>>NP_612200 (OMIM: 609333) trace amine-associated recept  (339 aa)
 initn: 887 init1: 481 opt: 920  Z-score: 924.7  bits: 179.5 E(85289): 9.2e-45
Smith-Waterman score: 920; 39.3% identity (71.4% similar) in 336 aa overlap (9-342:1-336)

               10        20        30        40        50        60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
               .. .:.. .: ::... .:   :. ::. . .  : .. :::.:..:. :::
NP_612         MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFK
                       10        20        30        40        50  

               70        80        90       100       110       120
pF1KE0 QLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVL
       :::.:::.:: :.: .:::.:  :: .::::..: :::::  :: .:.  :. .  .:..
NP_612 QLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIF
             60        70        80        90       100       110  

              130       140       150       160       170       180
pF1KE0 HLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELV
       :: :: :::: .: ::: : .:... :  . : .:: .: ... ....  .:  : ::. 
NP_612 HLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIY
            120       130       140       150       160       170  

               190       200        210       220       230        
pF1KE0 -SALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVE
        . ..: :::... :.   .. :.  :.::  .:. .: .:.::::.::  :  ...:..
NP_612 YKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQ
            180       190       200       210       220       230  

      240       250       260       270       280       290        
pF1KE0 SSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWS
        . :  .    ..::::.::::... .:.: : :. .  ..: :. .. :  . ..  : 
NP_612 IGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWF
            240       250       260       270       280       290  

      300       310       320       330       340     
pF1KE0 AYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE   
       .: ::..::..::.::::::::.:..: : ... .::  .::::   
NP_612 GYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
            300       310       320       330         

>>NP_001028252 (OMIM: 604849) trace amine-associated rec  (351 aa)
 initn: 846 init1: 516 opt: 851  Z-score: 856.3  bits: 166.9 E(85289): 5.9e-41
Smith-Waterman score: 851; 38.5% identity (68.6% similar) in 322 aa overlap (13-332:25-337)

                           10        20        30        40        
pF1KE0             MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVF
                               : :  : :: :.  : : :: .:. :  ::. ...:
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYS-FMAGSIFITIF
               10        20        30        40         50         

        50        60        70        80        90       100       
pF1KE0 GNLLVMTSVLHFKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLH
       ::: .. :. .:::::.:::::: :.: .:::.: :.: .::.:.::.:::::  :: ..
NP_001 GNLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIY
      60        70        80        90       100       110         

       110       120       130       140       150       160       
pF1KE0 SCCDVAFCYSSVLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVF
          :. .  .:..::: . :::. ..  ::.:.::.:. :    . . : .: ... .: 
NP_001 YSFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVV
     120       130       140       150       160       170         

       170       180       190       200        210       220      
pF1KE0 YTGVNDDGLEELVSALNCVGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQ
       .. .  ::.:     . : ..: .. .. :    :.  :: :  .:. .:.::: .....
NP_001 FSEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKH
     180       190       200       210       220       230         

        230       240       250       260       270       280      
pF1KE0 AIKIETTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
       :         ...  :. . .: :...:::::::... .:.. :.:    ::.: :..: 
NP_001 A-------HAINNLRENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFS
     240              250        260       270       280       290 

        290       300       310       320       330       340      
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE    
       ::. ...   : .:.::. :::::..::::::.:.: :: : ....              
NP_001 TPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
             300       310       320       330       340       350 

>>NP_055441 (OMIM: 604849) trace amine-associated recept  (306 aa)
 initn: 801 init1: 471 opt: 800  Z-score: 806.6  bits: 157.5 E(85289): 3.5e-38
Smith-Waterman score: 800; 37.9% identity (69.8% similar) in 298 aa overlap (37-332:3-292)

         10        20        30        40         50        60     
pF1KE0 QPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSL-LAVFGNLLVMTSVLHFKQLHSP
                                     .:  ::. ...:::: .. :. .:::::.:
NP_055                             MYSFMAGSIFITIFGNLAMIISISYFKQLHTP
                                           10        20        30  

          70        80        90       100       110       120     
pF1KE0 TNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSVLHLCFI
       ::::: :.: .:::.: :.: .::.:.::.:::::  :: ..   :. .  .:..::: .
NP_055 TNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSV
             40        50        60        70        80        90  

         130       140       150       160       170       180     
pF1KE0 CIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEELVSALNC
        :::. ..  ::.:.::.:. :    . . : .: ... .: .. .  ::.:     . :
NP_055 AIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVAC
            100       110       120       130       140       150  

         190       200        210       220       230       240    
pF1KE0 VGGCQIIVSQGWVLIDFLL-FFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVESSSESY
        ..: .. .. :    :.  :: :  .:. .:.::: .....:         ...  :. 
NP_055 SSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA-------HAINNLRENQ
            160       170       180       190              200     

          250       260       270       280       290       300    
pF1KE0 KIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSA
       . .: :...:::::::... .:.. :.:    ::.: :..: ::. ...   : .:.::.
NP_055 NNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNST
          210       220       230       240       250       260    

          310       320       330       340      
pF1KE0 MNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE    
        :::::..::::::.:.: :: : ....              
NP_055 CNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
          270       280       290       300      

>>XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A adrene  (317 aa)
 initn: 411 init1: 294 opt: 407  Z-score: 418.1  bits: 85.7 E(85289): 1.5e-16
Smith-Waterman score: 428; 31.4% identity (57.8% similar) in 287 aa overlap (18-273:11-288)

               10        20         30        40         50        
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPG-SRVILYTAFSFGSLL-AVFGNLLVMTSVLH
                        ...: . :   . :..::  ..  : .: .:.::.::. ::  
XP_016        MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVAC
                      10        20        30        40        50   

       60        70        80        90       100       110        
pF1KE0 FKQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSS
        ..::: :.. :..:: ::.:.  ::. :: .  : . : ::  ::.. .  ::  : .:
XP_016 HRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTAS
            60        70        80        90       100       110   

      120       130       140       150       160        170       
pF1KE0 VLHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYS-GAVFYTGVNDDGLE
       .. ::.: ::::: :. :: : :  :   . . .   : : :. : : .:       : .
XP_016 IMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GWR
           120       130       140       150       160             

       180       190       200        210       220       230      
pF1KE0 ELVSALNCVGGCQIIVSQGWVLIDFL-LFFIPTLVMIILYSKIFLIAKQQAIKIETTSSK
       . .   . .  :::    :.::.. :  :..:  .....: .....::...  ...  . 
XP_016 QPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKT
        170         180       190       200       210       220    

        240       250                                  260         
pF1KE0 VESSSESYKIRVAK---------------------------RERKAAKTLGVTVLAFVIS
        .:.::.  .:. .                           ::.:::::::..:  ::. 
XP_016 DKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLC
          230       240       250       260       270       280    

     270       280       290       300       310       320         
pF1KE0 WLPYTVDILIDAFMGFLTPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDV
       :::.                                                        
XP_016 WLPFFLVMPIGKKMKKLKVPWPEEGHRRKLTLS                           
          290       300       310                                  

>>NP_001035262 (OMIM: 602164) 5-hydroxytryptamine recept  (360 aa)
 initn: 461 init1: 206 opt: 405  Z-score: 415.6  bits: 85.4 E(85289): 2.1e-16
Smith-Waterman score: 583; 32.1% identity (64.5% similar) in 327 aa overlap (16-328:5-330)

               10        20        30        40        50        60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
                      :.: :  :  ..   .:.: : .:   :.:..::::::..:   .
NP_001            MDKLDANVSS-EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
                          10         20        30        40        

                70        80        90       100       110         
pF1KE0 QLHS-PTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
       ::..  ::..:.::: ::.::.: :: :. .. :.. : .:  :: ...  :: .  .:.
NP_001 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
       50        60        70        80        90       100        

     120       130        140       150       160       170        
pF1KE0 LHLCFICIDRYIVVT-DPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEE
       .::: : .::: ..  .:::: .:.:    .. ..  :..:   :   .. : :. :. .
NP_001 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
      110       120       130       140       150       160        

      180            190       200        210       220       230  
pF1KE0 LVSA--LNCVGG---CQIIVSQGWVLI-DFLLFFIPTLVMIILYSKIFLIAKQQAIKIE-
       :.    .:  ..   : ..:.. ...  . . :.:: :.:.. : .:.. ::..: .:. 
NP_001 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
      170       180       190       200       210       220        

                  240       250       260       270       280      
pF1KE0 -----TTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
            ..: .  .:..... .  . : :::::: . .  : . : :. :  ..: :. . 
NP_001 LQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT
      230       240       250       260       270       280        

        290       300       310       320       330       340      
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE    
       .:. ..    : .: ::..::..::..   ::.:. .::  :                  
NP_001 VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCST
      290       300       310       320       330       340        

NP_001 TTINGSTHVLRF
      350       360

>>NP_955525 (OMIM: 602164) 5-hydroxytryptamine receptor   (378 aa)
 initn: 438 init1: 206 opt: 405  Z-score: 415.3  bits: 85.4 E(85289): 2.1e-16
Smith-Waterman score: 583; 32.1% identity (64.5% similar) in 327 aa overlap (16-328:5-330)

               10        20        30        40        50        60
pF1KE0 MTSNFSQPVVQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHFK
                      :.: :  :  ..   .:.: : .:   :.:..::::::..:   .
NP_955            MDKLDANVSS-EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDR
                          10         20        30        40        

                70        80        90       100       110         
pF1KE0 QLHS-PTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
       ::..  ::..:.::: ::.::.: :: :. .. :.. : .:  :: ...  :: .  .:.
NP_955 QLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASI
       50        60        70        80        90       100        

     120       130        140       150       160       170        
pF1KE0 LHLCFICIDRYIVVT-DPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEE
       .::: : .::: ..  .:::: .:.:    .. ..  :..:   :   .. : :. :. .
NP_955 FHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIID
      110       120       130       140       150       160        

      180            190       200        210       220       230  
pF1KE0 LVSA--LNCVGG---CQIIVSQGWVLI-DFLLFFIPTLVMIILYSKIFLIAKQQAIKIE-
       :.    .:  ..   : ..:.. ...  . . :.:: :.:.. : .:.. ::..: .:. 
NP_955 LIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQM
      170       180       190       200       210       220        

                  240       250       260       270       280      
pF1KE0 -----TTSSKVESSSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFL
            ..: .  .:..... .  . : :::::: . .  : . : :. :  ..: :. . 
NP_955 LQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT
      230       240       250       260       270       280        

        290       300       310       320       330       340      
pF1KE0 TPAYIYEICCWSAYYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE    
       .:. ..    : .: ::..::..::..   ::.:. .::  :                  
NP_955 VPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCST
      290       300       310       320       330       340        

NP_955 TTINGSTHVLSGCSPVSSFLLLFCNRPVPV
      350       360       370        




342 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:32:31 2016 done: Sat Nov  5 03:32:32 2016
 Total Scan time:  7.500 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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