Result of FASTA (omim) for pF1KE0840
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0840, 345 aa
  1>>>pF1KE0840 345 - 345 aa - 345 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.4873+/-0.000497; mu= 21.3439+/- 0.031
 mean_var=136.7633+/-40.387, 0's: 0 Z-trim(108.9): 588  B-trim: 1064 in 1/50
 Lambda= 0.109670
 statistics sampled from 16285 (17068) to 16285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.55), E-opt: 0.2 (0.2), width:  16
 Scan time:  6.320

The best scores are:                                      opt bits E(85289)
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 2317 379.1 7.8e-105
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 1880 309.9   5e-84
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 1690 279.9 5.7e-75
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 1025 174.6 2.6e-43
NP_612200 (OMIM: 609333) trace amine-associated re ( 339)  941 161.4 2.7e-39
NP_001028252 (OMIM: 604849) trace amine-associated ( 351)  894 154.0 4.7e-37
NP_055441 (OMIM: 604849) trace amine-associated re ( 306)  861 148.6 1.6e-35
XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A ad ( 324)  473 87.3 5.1e-17
XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A ad ( 317)  472 87.1 5.6e-17
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308)  468 86.5 8.6e-17
NP_001309433 (OMIM: 104221) alpha-1A adrenergic re ( 342)  468 86.5   9e-17
NP_001309432 (OMIM: 104221) alpha-1A adrenergic re ( 370)  468 86.6 9.4e-17
NP_001309431 (OMIM: 104221) alpha-1A adrenergic re ( 372)  468 86.6 9.4e-17
XP_006716356 (OMIM: 104221) PREDICTED: alpha-1A ad ( 429)  468 86.7   1e-16
NP_150645 (OMIM: 104221) alpha-1A adrenergic recep ( 429)  468 86.7   1e-16
NP_150647 (OMIM: 104221) alpha-1A adrenergic recep ( 455)  468 86.7   1e-16
NP_000671 (OMIM: 104221) alpha-1A adrenergic recep ( 466)  468 86.8   1e-16
XP_016868583 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  468 86.8 1.1e-16
NP_150646 (OMIM: 104221) alpha-1A adrenergic recep ( 475)  468 86.8 1.1e-16
XP_016868584 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  468 86.8 1.1e-16
XP_006716355 (OMIM: 104221) PREDICTED: alpha-1A ad ( 475)  468 86.8 1.1e-16
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359)  429 80.4 6.6e-15
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362)  429 80.4 6.7e-15
NP_001124527 (OMIM: 142703) histamine H2 receptor  ( 397)  429 80.5   7e-15
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422)  429 80.5 7.2e-15
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422)  429 80.5 7.2e-15
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422)  429 80.5 7.2e-15
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422)  429 80.5 7.2e-15
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422)  429 80.5 7.2e-15
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412)  427 80.2 8.9e-15
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412)  427 80.2 8.9e-15
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412)  427 80.2 8.9e-15
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412)  427 80.2 8.9e-15
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412)  427 80.2 8.9e-15
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360)  418 78.7 2.2e-14
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378)  418 78.7 2.3e-14
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387)  418 78.7 2.3e-14
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388)  418 78.7 2.3e-14
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411)  418 78.8 2.4e-14
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428)  418 78.8 2.4e-14
NP_000015 (OMIM: 109690,600807,601665) beta-2 adre ( 413)  414 78.1 3.7e-14
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465)  403 76.5 1.3e-13
NP_000854 (OMIM: 182131) 5-hydroxytryptamine recep ( 390)  400 75.9 1.7e-13
NP_000673 (OMIM: 104260,607876) alpha-2B adrenergi ( 450)  397 75.5 2.5e-13
NP_000855 (OMIM: 182133) 5-hydroxytryptamine recep ( 377)  395 75.1 2.8e-13
NP_000674 (OMIM: 104250) alpha-2C adrenergic recep ( 462)  390 74.4 5.4e-13
XP_005265876 (OMIM: 104220) PREDICTED: alpha-1B ad ( 328)  386 73.5 7.1e-13
XP_006714884 (OMIM: 104220) PREDICTED: alpha-1B ad ( 331)  386 73.5 7.1e-13
XP_005265875 (OMIM: 104220) PREDICTED: alpha-1B ad ( 366)  386 73.6 7.5e-13
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478)  387 74.0 7.7e-13


>>NP_778237 (OMIM: 608923) trace amine-associated recept  (345 aa)
 initn: 2317 init1: 2317 opt: 2317  Z-score: 2003.1  bits: 379.1 E(85289): 7.8e-105
Smith-Waterman score: 2317; 100.0% identity (100.0% similar) in 345 aa overlap (1-345:1-345)

               10        20        30        40        50        60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
              250       260       270       280       290       300

              310       320       330       340     
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
       :::::::::::::::::::::::::::::::::::::::::::::
NP_778 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
              310       320       330       340     

>>NP_444508 (OMIM: 606927) trace amine-associated recept  (342 aa)
 initn: 1890 init1: 1870 opt: 1880  Z-score: 1629.5  bits: 309.9 E(85289): 5e-84
Smith-Waterman score: 1880; 79.6% identity (92.7% similar) in 343 aa overlap (1-343:1-342)

               10        20        30        40        50        60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
       :.:: :  : ::::: .:::::.. :.::::::::: .:.::..:::::::::: :.:::
NP_444 MTSNFSQPV-VQLCYEDVNGSCIETPYSPGSRVILYTAFSFGSLLAVFGNLLVMTSVLHF
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
       ::::::::::.::::::::::::::: :::::::::::::: .:::.:.::::::::::.
NP_444 KQLHSPTNFLIASLACADFLVGVTVMLFSMVRTVESCWYFGAKFCTLHSCCDVAFCYSSV
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
       .::::: :::::.::::::: :::::::::::::::::::: :::::::::: :::::::
NP_444 LHLCFICIDRYIVVTDPLVYATKFTVSVSGICISVSWILPLTYSGAVFYTGVNDDGLEEL
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
        .::::.:::: .:.:.::: ::: :::::..:::::..:::.:..:: :::.:.::.::
NP_444 VSALNCVGGCQIIVSQGWVLIDFLLFFIPTLVMIILYSKIFLIAKQQAIKIETTSSKVES
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
       :::::: :::.:::::::::::::.::.::::::..: ::::::::.::: ::::::: :
NP_444 SSESYKIRVAKRERKAAKTLGVTVLAFVISWLPYTVDILIDAFMGFLTPAYIYEICCWSA
     240       250       260       270       280       290         

              310       320       330       340     
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
       :::::::::::::::::::::::.:..:.::: ::.:..:: :  
NP_444 YYNSAMNPLIYALFYPWFRKAIKLILSGDVLKASSSTISLFLE  
     300       310       320       330       340    

>>NP_778227 (OMIM: 608282) trace amine-associated recept  (348 aa)
 initn: 1730 init1: 1682 opt: 1690  Z-score: 1467.0  bits: 279.9 E(85289): 5.7e-75
Smith-Waterman score: 1690; 69.0% identity (89.0% similar) in 345 aa overlap (1-345:1-345)

               10        20        30        40        50        60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
       : .: :   ::.::: ::: ::.: :.::: : ::: :.:::::::.::::::::.::::
NP_778 MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
       ::::.:::::.:::::::::::::::::: ::.:::::::: :.: :::: :..::..::
NP_778 KQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
       :::: ::.::::::::::.:::::::::::::: .::.. . :: ..::::. ..:.:::
NP_778 FHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEEL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTES
         ::.:.::::. .::::::  :: ::::.  :...:..:::::..::.:::.:.:...:
NP_778 VVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 SSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCA
       :::::: :::.::::::::::....::..::::: .:..:::.:.::::  .:::  ::.
NP_778 SSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCV
              250       260       270       280       290       300

              310       320       330       340        
pF1KE0 YYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI   
       ::::::::::::.:: :: ::::.::.:.::...:.: :::::..   
NP_778 YYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD
              310       320       330       340        

>>NP_003958 (OMIM: 607405) trace amine-associated recept  (337 aa)
 initn: 1037 init1: 699 opt: 1025  Z-score: 898.4  bits: 174.6 E(85289): 2.6e-43
Smith-Waterman score: 1025; 43.8% identity (74.9% similar) in 331 aa overlap (13-343:16-337)

                  10        20        30        40        50       
pF1KE0    MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISI
                      .:: .::::: .   . : ....:.. . : .. :.::..: ...
NP_003 MRAVFIQGAEEHPAAFCY-QVNGSCPRTVHTLGIQLVIYLACAAGMLIIVLGNVFVAFAV
               10         20        30        40        50         

        60        70        80        90       100       110       
pF1KE0 LHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCY
        .:: ::.:::::. ::: ::...:. :.:.: .:.:::::.::  .: .::  :. :: 
NP_003 SYFKALHTPTNFLLLSLALADMFLGLLVLPLSTIRSVESCWFFGDFLCRLHTYLDTLFCL
      60        70        80        90       100       110         

       120       130       140       150       160       170       
pF1KE0 SSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGL
       .:.::::::::::. :. :::.::.:::: :.   : ..: .:  :..  .:: : .  :
NP_003 TSIFHLCFISIDRHCAICDPLLYPSKFTVRVALRYILAGWGVPAAYTSLFLYTDVVETRL
     120       130       140       150       160       170         

       180       190       200       210       220       230       
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSK
        .  . . :.:.:: ..:. :   .:  ::.: .::: :: .::.:: :::..: .: ::
NP_003 SQWLEEMPCVGSCQLLLNKFWGWLNFPLFFVPCLIMISLYVKIFVVATRQAQQI-TTLSK
     180       190       200       210       220       230         

       240       250       260       270       280       290       
pF1KE0 TESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICC
       . ...       :..:::::::::..:  ... :::..::...:... ::::  ...:  
NP_003 SLAGA-------AKHERKAAKTLGIAVGIYLLCWLPFTIDTMVDSLLHFITPPLVFDIFI
      240              250       260       270       280       290 

       300       310       320       330       340     
pF1KE0 WCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI
       : ::.::: ::.::.. : :::::.:. .. .:.. .. :..:..:  
NP_003 WFAYFNSACNPIIYVFSYQWFRKALKLTLSQKVFSPQTRTVDLYQE  
             300       310       320       330         

>>NP_612200 (OMIM: 609333) trace amine-associated recept  (339 aa)
 initn: 932 init1: 506 opt: 941  Z-score: 826.6  bits: 161.4 E(85289): 2.7e-39
Smith-Waterman score: 941; 41.1% identity (72.1% similar) in 333 aa overlap (13-343:4-336)

               10        20        30        40        50        60
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHF
                   .:.  .: ::::  .:   :. :: .. .  . .. :::.:..:: ::
NP_612          MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHF
                        10        20        30        40        50 

               70        80        90       100       110       120
pF1KE0 KQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSL
       ::::.:::.:. :.: .:::.:  :::.::::..: :::::. :: .::  :. .  .:.
NP_612 KQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASI
              60        70        80        90       100       110 

              130       140       150       160       170       180
pF1KE0 FHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEEL
       ::: ::::::: :: ::: : .:... :  . : .:: .: ... ....  .   : ::.
NP_612 FHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEI
             120       130       140       150       160       170 

               190        200       210       220       230        
pF1KE0 S-DALNCIGGCQTVVNQ-NWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKT
           ..: :::..  .. . ::: . ::.::  ::. .:  :.:.:..::. : ....: 
NP_612 YYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKL
             180       190       200       210       220       230 

      240       250       260       270       280       290        
pF1KE0 ESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCW
       . . :  ..    .::::.::::... .:.: : :. : ...: :. .: :  . ..  :
NP_612 QIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIW
             240       250       260       270       280       290 

      300       310       320       330       340      
pF1KE0 CAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI 
        .: ::..::..::.::::::::.:... :......:.  .:: :   
NP_612 FGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
             300       310       320       330         

>>NP_001028252 (OMIM: 604849) trace amine-associated rec  (351 aa)
 initn: 867 init1: 500 opt: 894  Z-score: 786.3  bits: 154.0 E(85289): 4.7e-37
Smith-Waterman score: 894; 39.6% identity (70.1% similar) in 321 aa overlap (14-333:25-337)

                          10        20        30        40         
pF1KE0            MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFG
                               :    : :: .   : : :: .:  .. .  ...::
NP_001 MAVSSEQHELSHFKRTQTKKEKFNCSEYGNRSCPENERSLGVRVAMYSFMAGSIFITIFG
               10        20        30        40        50        60

      50        60        70        80        90       100         
pF1KE0 NLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHT
       :: ..::: .:::::.:::::. :.: .:::.: :.::.::.:.::.::::: .:: .. 
NP_001 NLAMIISISYFKQLHTPTNFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYY
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KE0 CCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFY
         :. .  .:.:::: ..:::. :.  ::.: ::.:. :    . . : .:  .. .: .
NP_001 SFDLMLSITSIFHLCSVAIDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVF
              130       140       150       160       170       180

     170       180       190       200        210       220        
pF1KE0 TGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQA
       . .: ::.:  .  . : ..: .. :. :  : :.. :: :  .:. .::.:: :.:..:
NP_001 SEAYADGIEGYDILVACSSSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHA
              190       200       210       220       230       240

      230       240       250       260       270       280        
pF1KE0 KKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFIT
       . :.:         :. . .: ....:::::::... .:.. :.:  .  :.: :..: :
NP_001 HAINNL-------RENQNNQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFST
                     250        260       270       280       290  

      290       300       310       320       330       340       
pF1KE0 PACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI  
       :. ...   : .:.::. :::::..::::::.:.: :. :.....              
NP_001 PVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
            300       310       320       330       340       350 

>>NP_055441 (OMIM: 604849) trace amine-associated recept  (306 aa)
 initn: 833 init1: 466 opt: 861  Z-score: 758.6  bits: 148.6 E(85289): 1.6e-35
Smith-Waterman score: 861; 40.4% identity (72.4% similar) in 297 aa overlap (39-333:4-292)

       10        20        30        40         50        60       
pF1KE0 VAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAV-LAVFGNLLVMISILHFKQLHSPT
                                     :  :.. ...:::: ..::: .:::::.::
NP_055                            MYSFMAGSIFITIFGNLAMIISISYFKQLHTPT
                                          10        20        30   

        70        80        90       100       110       120       
pF1KE0 NFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFIS
       :::. :.: .:::.: :.::.::.:.::.::::: .:: ..   :. .  .:.:::: ..
NP_055 NFLILSMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVA
            40        50        60        70        80        90   

       130       140       150       160       170       180       
pF1KE0 IDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCI
       :::. :.  ::.: ::.:. :    . . : .:  .. .: .. .: ::.:  .  . : 
NP_055 IDRFYAICYPLLYSTKITIPVIKRLLLLCWSVPGAFAFGVVFSEAYADGIEGYDILVACS
           100       110       120       130       140       150   

       190       200        210       220       230       240      
pF1KE0 GGCQTVVNQNWVLTDFLS-FFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYK
       ..: .. :. :  : :.. :: :  .:. .::.:: :.:..:. :.:         :. .
NP_055 SSCPVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSRKHAHAINNL-------RENQN
           160       170       180       190       200             

        250       260       270       280       290       300      
pF1KE0 ARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAM
        .: ....:::::::... .:.. :.:  .  :.: :..: ::. ...   : .:.::. 
NP_055 NQV-KKDKKAAKTLGIVIGVFLLCWFPCFFTILLDPFLNFSTPVVLFDALTWFGYFNSTC
         210       220       230       240       250       260     

        310       320       330       340       
pF1KE0 NPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI  
       :::::..::::::.:.: :. :.....              
NP_055 NPLIYGFFYPWFRRALKYILLGKIFSSCFHNTILCMQKESE
         270       280       290       300      

>>XP_011542713 (OMIM: 104221) PREDICTED: alpha-1A adrene  (324 aa)
 initn: 417 init1: 327 opt: 473  Z-score: 426.6  bits: 87.3 E(85289): 5.1e-17
Smith-Waterman score: 478; 32.6% identity (60.8% similar) in 291 aa overlap (16-274:8-288)

               10        20          30        40        50        
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
                      :. ...:..   : . .. ..: ...:   ...:.::.::..:. 
XP_011         MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
                       10        20        30        40        50  

       60        70        80        90       100       110        
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
         ..::: :.. ...:: ::.:.  ::.::: .  : . : ::: ::.. .  ::  : .
XP_011 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
             60        70        80        90       100       110  

      120       130       140       150       160        170       
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
       :.. ::.:::::::.:. :: :::  :   . . .   : : :. : : .:       : 
XP_011 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
            120       130       140       150       160            

       180       190       200        210       220       230      
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
       .. .   . :  ::   . ..:: . : ::..:  :....:  ...::.:... .. .: 
XP_011 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
         170         180       190       200       210        220  

        240        250                                  260        
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
       ::..: ::.   :. :                           ::.:::::::..:  :.
XP_011 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
            230       240       250       260       270       280  

      270       280       290       300       310       320        
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
       . :::.                                                      
XP_011 LCWLPFFLVMPIGTYILKYDVLFWRKGLSVCTRLRERKEIKN                  
            290       300       310       320                      

>>XP_016868585 (OMIM: 104221) PREDICTED: alpha-1A adrene  (317 aa)
 initn: 417 init1: 327 opt: 472  Z-score: 425.8  bits: 87.1 E(85289): 5.6e-17
Smith-Waterman score: 478; 32.6% identity (60.8% similar) in 291 aa overlap (16-274:8-288)

               10        20          30        40        50        
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
                      :. ...:..   : . .. ..: ...:   ...:.::.::..:. 
XP_016         MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
                       10        20        30        40        50  

       60        70        80        90       100       110        
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
         ..::: :.. ...:: ::.:.  ::.::: .  : . : ::: ::.. .  ::  : .
XP_016 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
             60        70        80        90       100       110  

      120       130       140       150       160        170       
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
       :.. ::.:::::::.:. :: :::  :   . . .   : : :. : : .:       : 
XP_016 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
            120       130       140       150       160            

       180       190       200        210       220       230      
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
       .. .   . :  ::   . ..:: . : ::..:  :....:  ...::.:... .. .: 
XP_016 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
         170         180       190       200       210        220  

        240        250                                  260        
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
       ::..: ::.   :. :                           ::.:::::::..:  :.
XP_016 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
            230       240       250       260       270       280  

      270       280       290       300       310       320        
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
       . :::.                                                      
XP_016 LCWLPFFLVMPIGKKMKKLKVPWPEEGHRRKLTLS                         
            290       300       310                                

>>XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A adrene  (308 aa)
 initn: 419 init1: 327 opt: 468  Z-score: 422.5  bits: 86.5 E(85289): 8.6e-17
Smith-Waterman score: 481; 32.5% identity (59.9% similar) in 302 aa overlap (16-285:8-299)

               10        20          30        40        50        
pF1KE0 MSSNSSLLVAVQLCYANVNGSCVK--IPFSPGSRVILYIVFGFGAVLAVFGNLLVMISIL
                      :. ...:..   : . .. ..: ...:   ...:.::.::..:. 
XP_011         MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVA
                       10        20        30        40        50  

       60        70        80        90       100       110        
pF1KE0 HFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYS
         ..::: :.. ...:: ::.:.  ::.::: .  : . : ::: ::.. .  ::  : .
XP_011 CHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTA
             60        70        80        90       100       110  

      120       130       140       150       160        170       
pF1KE0 SLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYS-GAVFYTGVYDDGL
       :.. ::.:::::::.:. :: :::  :   . . .   : : :. : : .:       : 
XP_011 SIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-------GW
            120       130       140       150       160            

       180       190       200        210       220       230      
pF1KE0 EELSDALNCIGGCQTVVNQNWVLTDFL-SFFIPTFIMIILYGNIFLVARRQAKKIENTGS
       .. .   . :  ::   . ..:: . : ::..:  :....:  ...::.:... .. .: 
XP_011 RQPAPEDETI--CQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLK-SGL
         170         180       190       200       210        220  

        240        250                                  260        
pF1KE0 KTESS-SESYKARVAR---------------------------RERKAAKTLGVTVVAFM
       ::..: ::.   :. :                           ::.:::::::..:  :.
XP_011 KTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFV
            230       240       250       260       270       280  

      270       280       290       300       310       320        
pF1KE0 ISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTG
       . :::. .   ::   :                                           
XP_011 LCWLPFFLVMPIDEQRGEGSGFSTHH                                  
            290       300                                          




345 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:31:54 2016 done: Sat Nov  5 03:31:55 2016
 Total Scan time:  6.320 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com