Result of FASTA (omim) for pF1KE0805
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0805, 360 aa
  1>>>pF1KE0805 360 - 360 aa - 360 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7543+/-0.00044; mu= 20.2508+/- 0.027
 mean_var=107.0731+/-28.658, 0's: 0 Z-trim(111.3): 394  B-trim: 1178 in 1/49
 Lambda= 0.123946
 statistics sampled from 19233 (19807) to 19233 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.232), width:  16
 Scan time:  7.740

The best scores are:                                      opt bits E(85289)
NP_063941 (OMIM: 155540,602025,607948) melanocorti ( 323) 2166 398.6  1e-110
NP_005904 (OMIM: 600042) melanocortin receptor 5 [ ( 325) 1325 248.2   2e-65
NP_005903 (OMIM: 155541,601665) melanocortin recep ( 332) 1273 238.9 1.3e-62
NP_002377 (OMIM: 155555,203200,266300,613098,61309 ( 317)  958 182.5 1.1e-45
NP_000520 (OMIM: 202200,607397) adrenocorticotropi ( 297)  583 115.4 1.6e-25
XP_016881270 (OMIM: 202200,607397) PREDICTED: adre ( 297)  583 115.4 1.6e-25
NP_001278840 (OMIM: 202200,607397) adrenocorticotr ( 297)  583 115.4 1.6e-25
NP_004221 (OMIM: 605111,610419,610419) sphingosine ( 353)  384 80.0 9.3e-15
NP_001391 (OMIM: 601974) sphingosine 1-phosphate r ( 382)  379 79.1 1.8e-14
NP_001307659 (OMIM: 601974) sphingosine 1-phosphat ( 382)  379 79.1 1.8e-14
XP_016882957 (OMIM: 605110) PREDICTED: lysophospha ( 351)  369 77.3 5.9e-14
NP_004711 (OMIM: 605110) lysophosphatidic acid rec ( 351)  369 77.3 5.9e-14
XP_011526723 (OMIM: 605110) PREDICTED: lysophospha ( 351)  369 77.3 5.9e-14
XP_016882958 (OMIM: 605110) PREDICTED: lysophospha ( 351)  369 77.3 5.9e-14
NP_036284 (OMIM: 605106) lysophosphatidic acid rec ( 353)  367 76.9 7.6e-14
NP_005217 (OMIM: 601965) sphingosine 1-phosphate r ( 378)  365 76.6   1e-13
NP_005275 (OMIM: 600553) G-protein coupled recepto ( 362)  333 70.8 5.2e-12
XP_016869881 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869894 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869887 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869886 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869893 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869895 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869880 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869883 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869885 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869884 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869892 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869874 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
NP_476500 (OMIM: 602282) lysophosphatidic acid rec ( 364)  333 70.9 5.3e-12
XP_016869891 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_005251839 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869872 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869878 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_005251838 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869876 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869877 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869896 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869873 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869882 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869875 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869888 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
NP_001392 (OMIM: 602282) lysophosphatidic acid rec ( 364)  333 70.9 5.3e-12
XP_016869889 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869879 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
XP_016869890 (OMIM: 602282) PREDICTED: lysophospha ( 364)  333 70.9 5.3e-12
NP_001273028 (OMIM: 600553) G-protein coupled rece ( 377)  333 70.9 5.4e-12
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369)  269 59.4 1.5e-08
NP_005279 (OMIM: 600752) G-protein coupled recepto ( 334)  252 56.3 1.1e-07
NP_110387 (OMIM: 605146) sphingosine 1-phosphate r ( 398)  250 56.1 1.6e-07


>>NP_063941 (OMIM: 155540,602025,607948) melanocortin re  (323 aa)
 initn: 2166 init1: 2166 opt: 2166  Z-score: 2108.5  bits: 398.6 E(85289): 1e-110
Smith-Waterman score: 2166; 100.0% identity (100.0% similar) in 323 aa overlap (38-360:1-323)

        10        20        30        40        50        60       
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQS
                                     ::::::::::::::::::::::::::::::
NP_063                               MNASCCLPSVQPTLPNGSEHLQAPFFSNQS
                                             10        20        30

        70        80        90       100       110       120       
pF1KE0 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 SSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVS
               40        50        60        70        80        90

       130       140       150       160       170       180       
pF1KE0 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 NALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYAL
              100       110       120       130       140       150

       190       200       210       220       230       240       
pF1KE0 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 RYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHM
              160       170       180       190       200       210

       250       260       270       280       290       300       
pF1KE0 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 FLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPT
              220       230       240       250       260       270

       310       320       330       340       350       360
pF1KE0 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_063 NPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
              280       290       300       310       320   

>>NP_005904 (OMIM: 600042) melanocortin receptor 5 [Homo  (325 aa)
 initn: 1280 init1: 891 opt: 1325  Z-score: 1295.7  bits: 248.2 E(85289): 2e-65
Smith-Waterman score: 1325; 61.6% identity (85.1% similar) in 323 aa overlap (38-359:1-317)

        10        20        30        40        50         60      
pF1KE0 LEGDFVFPVSSSSFLRTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSE-HLQAPFFSNQ
                                     ::.:  :  .. .: :..: .:..:  .:.
NP_005                               MNSSFHLHFLDLNL-NATEGNLSGPNVKNK
                                             10         20         

         70        80        90       100       110       120      
pF1KE0 SSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSV
       ::   ::.. :  ::::.::..::::::::: :.:.: :::::::::.:::::::::::.
NP_005 SSP--CEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSM
      30          40        50        60        70        80       

        130       140       150       160       170       180      
pF1KE0 SNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYA
       :.: ::: : .... .:.. : :..:.::.::::::::.:::.:.:::::::::::::::
NP_005 SSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYA
        90       100       110       120       130       140       

        190       200       210       220       230       240      
pF1KE0 LRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVH
       :::: :::.:.. ..:..::. :  ::.:::.:::: .::.:::.:::::..:. .::.:
NP_005 LRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIH
       150       160       170       180       190       200       

        250       260       270       280       290       300      
pF1KE0 MFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCP
       :::.:: ::::::::: :.  . .:.. :.::::.:.:::::  :::::::::.:...::
NP_005 MFLLARTHVKRIAALPGAS--SARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCP
       210       220         230       240       250       260     

        310       320       330       340       350       360      
pF1KE0 TNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG      
        : ::  . .::: ::.:::::::.::::::::: :.:.::.::.: : :. .       
NP_005 QNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIIC-CRGFRIACSFPRR
         270       280       290       300       310        320    

NP_005 D
        

>>NP_005903 (OMIM: 155541,601665) melanocortin receptor   (332 aa)
 initn: 1267 init1: 514 opt: 1273  Z-score: 1245.4  bits: 238.9 E(85289): 1.3e-62
Smith-Waterman score: 1273; 61.4% identity (85.5% similar) in 303 aa overlap (53-354:26-319)

             30        40        50        60        70         80 
pF1KE0 RTLLEPQLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFC-EQVFIKPEV
                                     :.:: :   .     :.. : ::.:..:::
NP_005      MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGY-----SDGGCYEQLFVSPEV
                    10        20        30             40        50

              90       100       110       120       130       140 
pF1KE0 FLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSD
       :..::..:::::::::.:...: :::::::::.::::::::::::::. :::.:....: 
NP_005 FVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNST
               60        70        80        90       100       110

             150       160       170       180       190       200 
pF1KE0 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL
         :  ..:  ..::..::.:: ::.::::.::.:::::: ::::::.::.::::...  .
NP_005 D-TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGII
               120       130       140       150       160         

             210       220       230       240       250       260 
pF1KE0 IVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAAL
       :  ::. : : :..::.::.:. ::.:::::::.:. ::..:::::::.::::.::::.:
NP_005 ISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVL
     170       180       190       200       210       220         

             270       280       290       300       310       320 
pF1KE0 PPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTY
       : . ..  .: . ::::.:.:::.:::. :::::::::.. :.:: ::::.:. .::: :
NP_005 PGTGAI--RQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLY
     230         240       250       260       270       280       

             330       340       350       360       
pF1KE0 LVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG       
       :.::::::.:::::::.:: :::.::.::.: :             
NP_005 LILIMCNSIIDPLIYALRSQELRKTFKEIIC-CYPLGGLCDLSSRY
       290       300       310        320       330  

>>NP_002377 (OMIM: 155555,203200,266300,613098,613099) m  (317 aa)
 initn: 940 init1: 584 opt: 958  Z-score: 941.2  bits: 182.5 E(85289): 1.1e-45
Smith-Waterman score: 958; 49.5% identity (77.6% similar) in 295 aa overlap (59-352:23-315)

       30        40        50        60        70        80        
pF1KE0 QLGSALLTAMNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIV
                                     :  . .::.. : : .: :.  .:::::.:
NP_002         MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTG-ARCLEVSISDGLFLSLGLV
                       10        20        30         40        50 

       90       100       110       120       130       140        
pF1KE0 SLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQ
       ::.:: ::. ....: ::::::: :.: ::..:.::: ::.::: .: ....  :. .  
NP_002 SLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAA
              60        70        80        90       100       110 

      150       160       170       180       190       200        
pF1KE0 FIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVC
        .:..::..: . : :...:.: : :::::::..::::::::::.:. .:   ..:::: 
NP_002 VLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVA
             120       130       140       150       160       170 

      210       220       230       240       250       260        
pF1KE0 CGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVA
         : ...::.: .   :..::...:.::..::..:::::.  :  :.. :: :   .  .
NP_002 SVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPV
             180       190       200       210       220       230 

      270       280       290       300       310       320        
pF1KE0 PQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCN
        :  . .:::::.:::::.:..::.::::::.::. :: .: : :   .:: .:.::.::
NP_002 HQGFG-LKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICN
              240       250       260       270       280       290

      330       340       350        360
pF1KE0 SVIDPLIYAFRSLELRNTFREIL-CGCNGMNLG
       ..::::::::.: ::: :..:.: :        
NP_002 AIIDPLIYAFHSQELRRTLKEVLTCSW      
              300       310             

>>NP_000520 (OMIM: 202200,607397) adrenocorticotropic ho  (297 aa)
 initn: 951 init1: 583 opt: 583  Z-score: 579.1  bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)

              50        60        70        80        90       100 
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
                                     : .: .  :.:....::..:::..:.::: 
NP_000           MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
                         10        20        30        40        50

             110       120       130       140       150       160 
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
       .: ::..:::::.::::..::: :. . ::.:.: . .  ::  . .:    :.:.::..
NP_000 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
               60        70        80        90       100       110

             170       180       190       200       210       220 
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
        .::..:: .: .::.:::.:::.:::::::.:.:........::. :   :......:.
NP_000 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
              120       130       140       150       160       170

             230       240       250       260       270       280 
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
          ... . ..:  :....  :::::::.:: :...:..:: :.         ::::.:.
NP_000 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
              180       190       200       210                220 

             290       300       310       320       330       340 
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
       :::::::::::::: ::..:.  ::.:::: :: . :..  .:::::.::::.:::::: 
NP_000 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
             230       240       250       260       270       280 

              350       360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
       :::..:.. :.:        
NP_000 ELRDAFKKMIFCSRYW    
             290           

>>XP_016881270 (OMIM: 202200,607397) PREDICTED: adrenoco  (297 aa)
 initn: 951 init1: 583 opt: 583  Z-score: 579.1  bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)

              50        60        70        80        90       100 
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
                                     : .: .  :.:....::..:::..:.::: 
XP_016           MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
                         10        20        30        40        50

             110       120       130       140       150       160 
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
       .: ::..:::::.::::..::: :. . ::.:.: . .  ::  . .:    :.:.::..
XP_016 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
               60        70        80        90       100       110

             170       180       190       200       210       220 
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
        .::..:: .: .::.:::.:::.:::::::.:.:........::. :   :......:.
XP_016 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
              120       130       140       150       160       170

             230       240       250       260       270       280 
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
          ... . ..:  :....  :::::::.:: :...:..:: :.         ::::.:.
XP_016 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
              180       190       200       210                220 

             290       300       310       320       330       340 
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
       :::::::::::::: ::..:.  ::.:::: :: . :..  .:::::.::::.:::::: 
XP_016 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
             230       240       250       260       270       280 

              350       360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
       :::..:.. :.:        
XP_016 ELRDAFKKMIFCSRYW    
             290           

>>NP_001278840 (OMIM: 202200,607397) adrenocorticotropic  (297 aa)
 initn: 951 init1: 583 opt: 583  Z-score: 579.1  bits: 115.4 E(85289): 1.6e-25
Smith-Waterman score: 940; 47.9% identity (79.8% similar) in 282 aa overlap (72-352:21-293)

              50        60        70        80        90       100 
pF1KE0 CCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVV
                                     : .: .  :.:....::..:::..:.::: 
NP_001           MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVF
                         10        20        30        40        50

             110       120       130       140       150       160 
pF1KE0 RNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMI
       .: ::..:::::.::::..::: :. . ::.:.: . .  ::  . .:    :.:.::..
NP_001 KNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLF
               60        70        80        90       100       110

             170       180       190       200       210       220 
pF1KE0 CISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSE
        .::..:: .: .::.:::.:::.:::::::.:.:........::. :   :......:.
NP_001 VLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSH
              120       130       140       150       160       170

             230       240       250       260       270       280 
pF1KE0 SKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTI
          ... . ..:  :....  :::::::.:: :...:..:: :.         ::::.:.
NP_001 HVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRAN---------MKGAITL
              180       190       200       210                220 

             290       300       310       320       330       340 
pF1KE0 TILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSL
       :::::::::::::: ::..:.  ::.:::: :: . :..  .:::::.::::.:::::: 
NP_001 TILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSP
             230       240       250       260       270       280 

              350       360
pF1KE0 ELRNTFRE-ILCGCNGMNLG
       :::..:.. :.:        
NP_001 ELRDAFKKMIFCSRYW    
             290           

>>NP_004221 (OMIM: 605111,610419,610419) sphingosine 1-p  (353 aa)
 initn: 355 init1: 135 opt: 384  Z-score: 386.0  bits: 80.0 E(85289): 9.3e-15
Smith-Waterman score: 430; 32.7% identity (61.2% similar) in 327 aa overlap (52-359:11-312)

              30        40        50         60        70        80
pF1KE0 LRTLLEPQLGSALLTAMNASCCLPSVQPTLPNG-SEHLQAPFFSNQSSSAFCEQVFIKPE
                                     ::  .:: .    . ... .  .::     
NP_004                     MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFI
                                   10        20        30        40

               90       100       110       120       130       140
pF1KE0 VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS
       :.:  .::  .::.::..::.::...:: ::.:: .::..:.:..:. . .:.. . : .
NP_004 VILCCAIV--VENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSV-T
                 50        60        70        80        90        

              150       160       170       180       190       200
pF1KE0 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT
         ::   :.. .  . :     :.: ::. .:::::..:.:.:  .  : :  . :  : 
NP_004 LRLT-PVQWFAREGSAF-----ITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCR-MLL
       100        110            120       130       140        150

                            210          220       230       240   
pF1KE0 LIVAIWV--------------CCG---VCGVVFIVYSESKMVIVCLITMFFAMMLLMGTL
       :: : :.              : :   .:..:. .:  .:  ..:..:.:  ..: . .:
NP_004 LIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLY--AKHYVLCVVTIFSIILLAIVAL
              160       170       180         190       200        

           250       260       270       280       290       300   
pF1KE0 YVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLII
       ::...  .:           :: .:::  . .:   :.::.::::: :: : :  :.:  
NP_004 YVRIYCVVRSS--------HADMAAPQTLALLK---TVTIVLGVFIVCWLPAFSILLLDY
      210               220       230          240       250       

           310       320       330       340        350       360  
pF1KE0 TCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELR-NTFREILCGCNGMNLG  
       .::..   : : ::.  ....   ::...:.::..:: .:: ...: . :   :...   
NP_004 ACPVHSCPILYKAHY--FFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGR
       260       270         280       290       300       310     

NP_004 RRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
         320       330       340       350   

>>NP_001391 (OMIM: 601974) sphingosine 1-phosphate recep  (382 aa)
 initn: 324 init1: 126 opt: 379  Z-score: 380.8  bits: 79.1 E(85289): 1.8e-14
Smith-Waterman score: 391; 28.0% identity (63.1% similar) in 293 aa overlap (81-354:51-331)

               60        70        80        90       100       110
pF1KE0 LPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPM
                                     ::. .    .::::.:.:.. .. ..: ::
NP_001 NYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPM
               30        40        50        60        70        80

              120       130       140       150       160       170
pF1KE0 YFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASIC
       :.:. .::..:.:..:. .  ..... . .  ::  . :...      ::. ..: ::. 
NP_001 YYFIGNLALSDLLAGVAYT-ANLLLSGATTYKLTPAQWFLRE-----GSMF-VALSASVF
               90        100       110       120             130   

              180       190       200                     210      
pF1KE0 NLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV--------------CCGV---CG
       .:::::..::.:..  .. :.  .  . . :: : ::              : ..   :.
NP_001 SLLAIAIERYITML-KMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCS
           140        150       160       170       180       190  

           220       230       240       250       260       270   
pF1KE0 VVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHS
       .:. .: . .... :  :.:  ..: .  :: ... ..: . .:..     . .. ....
NP_001 TVLPLYHK-HYILFCT-TVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEK
            200         210       220       230       240       250

           280       290       300       310       320       330   
pF1KE0 CMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDP
        .    :. :.:.::: ::::.:. :.: . : ..   : . :..  .::: . ::  .:
NP_001 SLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY--FLVLAVLNSGTNP
              260       270       280       290         300        

           340       350         360                               
pF1KE0 LIYAFRSLELRNTFREIL--CGCNGMNLG                               
       .::.. . :.: .: .:.  : :                                     
NP_001 IIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDN
      310       320       330       340       350       360        

>>NP_001307659 (OMIM: 601974) sphingosine 1-phosphate re  (382 aa)
 initn: 324 init1: 126 opt: 379  Z-score: 380.8  bits: 79.1 E(85289): 1.8e-14
Smith-Waterman score: 391; 28.0% identity (63.1% similar) in 293 aa overlap (81-354:51-331)

               60        70        80        90       100       110
pF1KE0 LPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPM
                                     ::. .    .::::.:.:.. .. ..: ::
NP_001 NYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPM
               30        40        50        60        70        80

              120       130       140       150       160       170
pF1KE0 YFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASIC
       :.:. .::..:.:..:. .  ..... . .  ::  . :...      ::. ..: ::. 
NP_001 YYFIGNLALSDLLAGVAYT-ANLLLSGATTYKLTPAQWFLRE-----GSMF-VALSASVF
               90        100       110       120             130   

              180       190       200                     210      
pF1KE0 NLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWV--------------CCGV---CG
       .:::::..::.:..  .. :.  .  . . :: : ::              : ..   :.
NP_001 SLLAIAIERYITML-KMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCS
           140        150       160       170       180       190  

           220       230       240       250       260       270   
pF1KE0 VVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHS
       .:. .: . .... :  :.:  ..: .  :: ... ..: . .:..     . .. ....
NP_001 TVLPLYHK-HYILFCT-TVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEK
            200         210       220       230       240       250

           280       290       300       310       320       330   
pF1KE0 CMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDP
        .    :. :.:.::: ::::.:. :.: . : ..   : . :..  .::: . ::  .:
NP_001 SLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY--FLVLAVLNSGTNP
              260       270       280       290         300        

           340       350         360                               
pF1KE0 LIYAFRSLELRNTFREIL--CGCNGMNLG                               
       .::.. . :.: .: .:.  : :                                     
NP_001 IIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDN
      310       320       330       340       350       360        




360 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 03:14:45 2016 done: Sat Nov  5 03:14:46 2016
 Total Scan time:  7.740 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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