Result of FASTA (ccds) for pF1KE0439
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0439, 314 aa
  1>>>pF1KE0439 314 - 314 aa - 314 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2702+/-0.000951; mu= 15.5832+/- 0.057
 mean_var=60.6621+/-12.005, 0's: 0 Z-trim(103.7): 22  B-trim: 7 in 1/50
 Lambda= 0.164670
 statistics sampled from 7540 (7551) to 7540 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.232), width:  16
 Scan time:  2.220

The best scores are:                                      opt bits E(32554)
CCDS3678.1 HADH gene_id:3033|Hs108|chr4            ( 314) 1972 477.1 7.6e-135
CCDS82943.1 HADH gene_id:3033|Hs108|chr4           ( 318) 1715 416.1 1.8e-116
CCDS54790.1 HADH gene_id:3033|Hs108|chr4           ( 331) 1437 350.0 1.4e-96
CCDS1721.1 HADHA gene_id:3030|Hs108|chr2           ( 763)  548 139.0 1.1e-32
CCDS54694.1 EHHADH gene_id:1962|Hs108|chr3         ( 627)  441 113.5 4.3e-25
CCDS33901.1 EHHADH gene_id:1962|Hs108|chr3         ( 723)  441 113.6 4.8e-25
CCDS41871.1 CRYL1 gene_id:51084|Hs108|chr13        ( 319)  307 81.6 9.1e-16


>>CCDS3678.1 HADH gene_id:3033|Hs108|chr4                 (314 aa)
 initn: 1972 init1: 1972 opt: 1972  Z-score: 2534.4  bits: 477.1 E(32554): 7.6e-135
Smith-Waterman score: 1972; 99.7% identity (99.7% similar) in 314 aa overlap (1-314:1-314)

               10        20        30        40        50        60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
       ::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS36 DILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDAS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 KEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAEN
              250       260       270       280       290       300

              310    
pF1KE0 KFGKKTGEGFYKYK
       ::::::::::::::
CCDS36 KFGKKTGEGFYKYK
              310    

>>CCDS82943.1 HADH gene_id:3033|Hs108|chr4                (318 aa)
 initn: 1715 init1: 1715 opt: 1715  Z-score: 2204.3  bits: 416.1 E(32554): 1.8e-116
Smith-Waterman score: 1715; 98.2% identity (98.9% similar) in 275 aa overlap (40-314:44-318)

      10        20        30        40        50        60         
pF1KE0 RSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG
                                     : . .:::::::::::::::::::::::::
CCDS82 LGVCWRKEHDPAEMLRVGRAELGGWKPSWEAIVKEVAAATGHTVVLVDQTEDILAKSKKG
            20        30        40        50        60        70   

      70        80        90       100       110       120         
pF1KE0 IEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE
       :::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
CCDS82 IEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNE
            80        90       100       110       120       130   

     130       140       150       160       170       180         
pF1KE0 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMT
           140       150       160       170       180       190   

     190       200       210       220       230       240         
pF1KE0 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 SQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMK
           200       210       220       230       240       250   

     250       260       270       280       290       300         
pF1KE0 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEG
           260       270       280       290       300       310   

     310    
pF1KE0 FYKYK
       :::::
CCDS82 FYKYK
            

>>CCDS54790.1 HADH gene_id:3033|Hs108|chr4                (331 aa)
 initn: 1436 init1: 1436 opt: 1437  Z-score: 1847.1  bits: 350.0 E(32554): 1.4e-96
Smith-Waterman score: 1928; 94.6% identity (94.6% similar) in 331 aa overlap (1-314:1-331)

               10        20        30        40        50        60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
       ::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
CCDS54 DILAKSKKGIEESLRKVAKKKFAENLKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
              130       140       150       160       170       180

              190       200       210       220       230          
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER----
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
CCDS54 VEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERDFQT
              190       200       210       220       230       240

                     240       250       260       270       280   
pF1KE0 -------------GDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE
                    :::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 CGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAE
              250       260       270       280       290       300

           290       300       310    
pF1KE0 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
       :::::::::::::::::::::::::::::::
CCDS54 NPLHQPSPSLNKLVAENKFGKKTGEGFYKYK
              310       320       330 

>>CCDS1721.1 HADHA gene_id:3030|Hs108|chr2                (763 aa)
 initn: 380 init1: 252 opt: 548  Z-score: 700.1  bits: 139.0 E(32554): 1.1e-32
Smith-Waterman score: 548; 34.1% identity (66.2% similar) in 290 aa overlap (27-314:361-640)

                   10        20        30        40        50      
pF1KE0     MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLV
                                     :::....:.::::::::::..  :  ..: 
CCDS17 VMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILK
              340       350       360       370       380       390

         60        70        80        90       100       110      
pF1KE0 DQTEDILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLV
       : :   : .... . ..:   .:::      :   : . .. .  :.    .  ...:.:
CCDS17 DATLTALDRGQQQVFKGLNDKVKKK------ALTSFERDSIFSNLTGQLDYQGFEKADMV
              400       410             420       430       440    

        120       130       140       150       160       170      
pF1KE0 VEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVP
       .::. :.:..:....:...    .: :::::::.: :. :: .. : ..  :.:.:.:: 
CCDS17 IEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVD
          450       460       470       480       490       500    

        180       190       200       210       220       230      
pF1KE0 VMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYER
        :.:.:.: :  ::. :  : :  .   ::  .  :: ::: ..: :.:.. :.::. ..
CCDS17 KMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQE
          510       520       530       540       550       560    

         240       250       260       270       280       290     
pF1KE0 G-DASKEDIDTAMKLGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSL-N
       : : .: :   ..  . :.:.:   :.: ::.:..: ...   .. .:  .   .: : .
CCDS17 GVDPKKLD---SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGER-FGGGNPELLT
          570          580       590       600       610        620

          300       310                                            
pF1KE0 KLVAENKFGKKTGEGFYKYK                                        
       ..:... .:.:.:.::: :.                                        
CCDS17 QMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTR
              630       640       650       660       670       680

>>CCDS54694.1 EHHADH gene_id:1962|Hs108|chr3              (627 aa)
 initn: 468 init1: 286 opt: 441  Z-score: 564.0  bits: 113.5 E(32554): 4.3e-25
Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:189-486)

                                 10        20        30        40  
pF1KE0                   MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI
                                     :..:  .:::.   :. : :.: : :: ::
CCDS54 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI
      160       170       180       190       200         210      

             50        60        70        80         90       100 
pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA
       .   : .   :. ::. .. :: ..: :   :.: :.: . . .: .: .   .  :.. 
CCDS54 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK
        220       230       240       250       260         270    

             110       120       130       140       150       160 
pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT
               . ..:::.::. :....:...: .:.     .... .:::.:..  ::..: 
CCDS54 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD
                 280       290       300       310       320       

             170       180       190       200       210       220 
pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR
       :     : :::.:. ::::.::: . ..:  :. .....:: . :  :   .  ::. ::
CCDS54 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR
       330       340       350       360       370       380       

             230       240       250       260                  270
pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT
       .: ::  .:  : :.: .. :..: ...   :. ::::.. : .:::           : 
CCDS54 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG
       390       400        410        420       430       440     

              280       290       300       310                    
pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK                
         .. :       :  . : :..  :   ..::.:::.:.:.:                 
CCDS54 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF
         450       460         470       480       490       500   

CCDS54 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH
           510       520       530       540       550       560   

>>CCDS33901.1 EHHADH gene_id:1962|Hs108|chr3              (723 aa)
 initn: 468 init1: 286 opt: 441  Z-score: 563.1  bits: 113.6 E(32554): 4.8e-25
Smith-Waterman score: 455; 31.9% identity (60.1% similar) in 313 aa overlap (13-313:285-582)

                                 10        20        30        40  
pF1KE0                   MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGI
                                     :..:  .:::.   :. : :.: : :: ::
CCDS33 LFLYLLQSGQARALQYAFFAERKANKWSTPSGASWKTASARP--VSSVGVVGLGTMGRGI
          260       270       280       290         300       310  

             50        60        70        80         90       100 
pF1KE0 AQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-KFAENPKAGDEFVEKTLSTIA
       .   : .   :. ::. .. :: ..: :   :.: :.: . . .: .: .   .  :.. 
CCDS33 VISFARARIPVIAVDSDKNQLATANKMITSVLEKEASKMQQSGHPWSGPK--PRLTSSVK
            320       330       340       350       360         370

             110       120       130       140       150       160 
pF1KE0 TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATT
               . ..:::.::. :....:...: .:.     .... .:::.:..  ::..: 
CCDS33 E-------LGGVDLVIEAVFEEMSLKKQVFAELSAVCKPEAFLCTNTSALDVDEIASSTD
                     380       390       400       410       420   

             170       180       190       200       210       220 
pF1KE0 RQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNR
       :     : :::.:. ::::.::: . ..:  :. .....:: . :  :   .  ::. ::
CCDS33 RPHLVIGTHFFSPAHVMKLLEVIPSQYSSPTTIATVMNLSKKIKKIGVVVGNCFGFVGNR
           430       440       450       460       470       480   

             230       240       250       260                  270
pF1KE0 LLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVGLD-----------TT
       .: ::  .:  : :.: .. :..: ...   :. ::::.. : .:::           : 
CCDS33 MLNPYYNQAYFLLEEG-SKPEEVDQVLEE-FGFKMGPFRVSDLAGLDVGWKSRKGQGLTG
           490        500       510        520       530       540 

              280       290       300       310                    
pF1KE0 KFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK                
         .. :       :  . : :..  :   ..::.:::.:.:.:                 
CCDS33 PTLLPGTPARKRGNRRYCPIPDV--LCELGRFGQKTGKGWYQYDKPLGRIHKPDPWLSKF
             550       560         570       580       590         

CCDS33 LSRYRKTHHIEPRTISQDEILERCLYSLINEAFRILGEGIAASPEHIDVVYLHGYGWPRH
     600       610       620       630       640       650         

>>CCDS41871.1 CRYL1 gene_id:51084|Hs108|chr13             (319 aa)
 initn: 238 init1: 150 opt: 307  Z-score: 396.5  bits: 81.6 E(32554): 9.1e-16
Smith-Waterman score: 307; 28.3% identity (59.1% similar) in 237 aa overlap (30-262:9-241)

               10        20        30        40        50        60
pF1KE0 MAFVTRQFMRSVSSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTE
                                    :...:.:..: . :.. :. :  : : :   
CCDS41                      MASSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYD---
                                    10        20        30         

               70        80        90       100       110       120
pF1KE0 DILAKSKKGIEESLRKVAKKKFAENPKAGDEFVEKTLSTIATSTDAASVVHSTDLVVEAI
        :  .. ..  :..::  :     .   :.  ::. :: :.   .   .:...  . : .
CCDS41 -IEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECV
          40        50        60        70        80        90     

              130       140       150       160       170       180
pF1KE0 VENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKL
        :.:..:...: .::..  ...:..:.:: :. ...  . ..  .    :  ::   . :
CCDS41 PEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPL
         100       110       120       130       140       150     

              190       200       210        220       230         
pF1KE0 VEVIKTPMTSQKTFESLVDFSKALGKHPVSC-KDTPGFIVNRLLVPYLMEAIRLYERGDA
       ::..  : :.  : .    . : .:. :.   :.. ::..:::    . :: :: :.: .
CCDS41 VELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIV
         160       170       180       190       200       210     

     240       250          260       270       280       290      
pF1KE0 SKEDIDTAMKLGAGYP---MGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKL
       :  :.: .:. : :.    .::.: .                                  
CCDS41 SPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRA
         220       230       240       250       260       270     




314 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 08:54:35 2016 done: Thu Nov  3 08:54:35 2016
 Total Scan time:  2.220 Total Display time:  0.020

Function used was FASTA [36.3.4 Apr, 2011]
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