Result of FASTA (omim) for pF1KE0075
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE0075, 1447 aa
  1>>>pF1KE0075 1447 - 1447 aa - 1447 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 9.8199+/-0.000471; mu= 2.9974+/- 0.029
 mean_var=264.3401+/-55.524, 0's: 0 Z-trim(118.8): 52  B-trim: 1293 in 2/51
 Lambda= 0.078885
 statistics sampled from 32000 (32055) to 32000 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.376), width:  16
 Scan time: 19.710

The best scores are:                                      opt bits E(85289)
NP_000255 (OMIM: 109400,601309,605462,610828) prot (1447) 9793 1129.3       0
NP_001077072 (OMIM: 109400,601309,605462,610828) p (1446) 9327 1076.2       0
NP_001077071 (OMIM: 109400,601309,605462,610828) p (1381) 9321 1075.5       0
NP_001077075 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6       0
NP_001077073 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6       0
NP_001077074 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6       0
NP_001077076 (OMIM: 109400,601309,605462,610828) p (1296) 8768 1012.6       0
NP_001159764 (OMIM: 109400,155255,603673,605462) p (1146) 2010 243.4 7.4e-63
NP_003729 (OMIM: 109400,155255,603673,605462) prot (1203) 2010 243.5 7.6e-63
XP_011524317 (OMIM: 257220,607623) PREDICTED: Niem (1148)  439 64.7 4.9e-09
XP_016881276 (OMIM: 257220,607623) PREDICTED: Niem (1256)  439 64.7 5.2e-09
XP_016881275 (OMIM: 257220,607623) PREDICTED: Niem (1264)  439 64.7 5.3e-09
XP_016881274 (OMIM: 257220,607623) PREDICTED: Niem (1273)  439 64.7 5.3e-09
XP_006722542 (OMIM: 257220,607623) PREDICTED: Niem (1273)  439 64.7 5.3e-09
NP_000262 (OMIM: 257220,607623) Niemann-Pick C1 pr (1278)  439 64.7 5.3e-09
XP_016881273 (OMIM: 257220,607623) PREDICTED: Niem (1281)  439 64.7 5.3e-09
XP_005258336 (OMIM: 257220,607623) PREDICTED: Niem (1286)  439 64.7 5.3e-09
XP_005258335 (OMIM: 257220,607623) PREDICTED: Niem (1295)  439 64.7 5.4e-09
XP_005258334 (OMIM: 257220,607623) PREDICTED: Niem (1303)  439 64.7 5.4e-09
NP_001095118 (OMIM: 608010) Niemann-Pick C1-like p (1332)  374 57.3 9.2e-07
NP_037521 (OMIM: 608010) Niemann-Pick C1-like prot (1359)  374 57.3 9.4e-07
XP_011513630 (OMIM: 608010) PREDICTED: Niemann-Pic ( 785)  367 56.3 1.1e-06
XP_016866382 (OMIM: 616908) PREDICTED: patched dom ( 843)  291 47.7 0.00045
NP_001013754 (OMIM: 616908) patched domain-contain ( 846)  291 47.7 0.00045
XP_016866381 (OMIM: 616908) PREDICTED: patched dom ( 901)  291 47.7 0.00048
XP_016866380 (OMIM: 616908) PREDICTED: patched dom ( 904)  291 47.7 0.00048
NP_775766 (OMIM: 300828,300830) patched domain-con ( 888)  271 45.5  0.0023
XP_011543751 (OMIM: 300828,300830) PREDICTED: patc ( 888)  271 45.5  0.0023
XP_011512941 (OMIM: 616908) PREDICTED: patched dom ( 593)  250 42.9  0.0087


>>NP_000255 (OMIM: 109400,601309,605462,610828) protein   (1447 aa)
 initn: 9793 init1: 9793 opt: 9793  Z-score: 6035.1  bits: 1129.3 E(85289):    0
Smith-Waterman score: 9793; 100.0% identity (100.0% similar) in 1447 aa overlap (1-1447:1-1447)

               10        20        30        40        50        60
pF1KE0 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAF
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE0 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAAN
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE0 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE0 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAK
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE0 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE0 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHAL
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE0 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVL
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE0 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALS
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE0 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGEC
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE0 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE0 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQS
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE0 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSL
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE0 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDI
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE0 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE0 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDIS
              850       860       870       880       890       900

              910       920       930       940       950       960
pF1KE0 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETR
              910       920       930       940       950       960

              970       980       990      1000      1010      1020
pF1KE0 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQ
              970       980       990      1000      1010      1020

             1030      1040      1050      1060      1070      1080
pF1KE0 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSA
             1030      1040      1050      1060      1070      1080

             1090      1100      1110      1120      1130      1140
pF1KE0 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLML
             1090      1100      1110      1120      1130      1140

             1150      1160      1170      1180      1190      1200
pF1KE0 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEP
             1150      1160      1170      1180      1190      1200

             1210      1220      1230      1240      1250      1260
pF1KE0 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATE
             1210      1220      1230      1240      1250      1260

             1270      1280      1290      1300      1310      1320
pF1KE0 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRR
             1270      1280      1290      1300      1310      1320

             1330      1340      1350      1360      1370      1380
pF1KE0 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVA
             1330      1340      1350      1360      1370      1380

             1390      1400      1410      1420      1430      1440
pF1KE0 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEER
             1390      1400      1410      1420      1430      1440

              
pF1KE0 PRGSSSN
       :::::::
NP_000 PRGSSSN
              

>>NP_001077072 (OMIM: 109400,601309,605462,610828) prote  (1446 aa)
 initn: 9327 init1: 9327 opt: 9327  Z-score: 5748.5  bits: 1076.2 E(85289):    0
Smith-Waterman score: 9327; 100.0% identity (100.0% similar) in 1381 aa overlap (67-1447:66-1446)

         40        50        60        70        80        90      
pF1KE0 GGLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQK
                                     ::::::::::::::::::::::::::::::
NP_001 FCKDGGGGEEEEENGGEEKDDRGDKETRSDKGKATGRKAPLWLRAKFQRLLFKLGCYIQK
          40        50        60        70        80        90     

        100       110       120       130       140       150      
pF1KE0 NCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
         100       110       120       130       140       150     

        160       170       180       190       200       210      
pF1KE0 LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYM
         160       170       180       190       200       210     

        220       230       240       250       260       270      
pF1KE0 DQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVD
         220       230       240       250       260       270     

        280       290       300       310       320       330      
pF1KE0 SWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
         280       290       300       310       320       330     

        340       350       360       370       380       390      
pF1KE0 WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAIL
         340       350       360       370       380       390     

        400       410       420       430       440       450      
pF1KE0 EAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLT
         400       410       420       430       440       450     

        460       470       480       490       500       510      
pF1KE0 MLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
         460       470       480       490       500       510     

        520       530       540       550       560       570      
pF1KE0 LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQ
         520       530       540       550       560       570     

        580       590       600       610       620       630      
pF1KE0 AAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDN
         580       590       600       610       620       630     

        640       650       660       670       680       690      
pF1KE0 TRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
         640       650       660       670       680       690     

        700       710       720       730       740       750      
pF1KE0 LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFL
         700       710       720       730       740       750     

        760       770       780       790       800       810      
pF1KE0 FLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQ
         760       770       780       790       800       810     

        820       830       840       850       860       870      
pF1KE0 HLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
         820       830       840       850       860       870     

        880       890       900       910       920       930      
pF1KE0 SDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAA
         880       890       900       910       920       930     

        940       950       960       970       980       990      
pF1KE0 SQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRT
         940       950       960       970       980       990     

       1000      1010      1020      1030      1040      1050      
pF1KE0 ICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGII
        1000      1010      1020      1030      1040      1050     

       1060      1070      1080      1090      1100      1110      
pF1KE0 VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAV
        1060      1070      1080      1090      1100      1110     

       1120      1130      1140      1150      1160      1170      
pF1KE0 LALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLS
        1120      1130      1140      1150      1160      1170     

       1180      1190      1200      1210      1220      1230      
pF1KE0 FFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSE
        1180      1190      1200      1210      1220      1230     

       1240      1250      1260      1270      1280      1290      
pF1KE0 ELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPG
        1240      1250      1260      1270      1280      1290     

       1300      1310      1320      1330      1340      1350      
pF1KE0 RQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTA
        1300      1310      1320      1330      1340      1350     

       1360      1370      1380      1390      1400      1410      
pF1KE0 MGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPF
        1360      1370      1380      1390      1400      1410     

       1420      1430      1440       
pF1KE0 HVRCERRDSKVEVIELQDVECEERPRGSSSN
       :::::::::::::::::::::::::::::::
NP_001 HVRCERRDSKVEVIELQDVECEERPRGSSSN
        1420      1430      1440      

>>NP_001077071 (OMIM: 109400,601309,605462,610828) prote  (1381 aa)
 initn: 9321 init1: 9321 opt: 9321  Z-score: 5745.1  bits: 1075.5 E(85289):    0
Smith-Waterman score: 9321; 100.0% identity (100.0% similar) in 1380 aa overlap (68-1447:2-1381)

        40        50        60        70        80        90       
pF1KE0 GLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKN
                                     ::::::::::::::::::::::::::::::
NP_001                              MGKATGRKAPLWLRAKFQRLLFKLGCYIQKN
                                            10        20        30 

       100       110       120       130       140       150       
pF1KE0 CGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQL
              40        50        60        70        80        90 

       160       170       180       190       200       210       
pF1KE0 MIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMD
             100       110       120       130       140       150 

       220       230       240       250       260       270       
pF1KE0 QIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDS
             160       170       180       190       200       210 

       280       290       300       310       320       330       
pF1KE0 WEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHW
             220       230       240       250       260       270 

       340       350       360       370       380       390       
pF1KE0 QEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILE
             280       290       300       310       320       330 

       400       410       420       430       440       450       
pF1KE0 AWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTM
             340       350       360       370       380       390 

       460       470       480       490       500       510       
pF1KE0 LRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFL
             400       410       420       430       440       450 

       520       530       540       550       560       570       
pF1KE0 LAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQA
             460       470       480       490       500       510 

       580       590       600       610       620       630       
pF1KE0 AVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNT
             520       530       540       550       560       570 

       640       650       660       670       680       690       
pF1KE0 RYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTL
             580       590       600       610       620       630 

       700       710       720       730       740       750       
pF1KE0 SCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLF
             640       650       660       670       680       690 

       760       770       780       790       800       810       
pF1KE0 LGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQH
             700       710       720       730       740       750 

       820       830       840       850       860       870       
pF1KE0 LLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
             760       770       780       790       800       810 

       880       890       900       910       920       930       
pF1KE0 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
             820       830       840       850       860       870 

       940       950       960       970       980       990       
pF1KE0 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
             880       890       900       910       920       930 

      1000      1010      1020      1030      1040      1050       
pF1KE0 CSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIV
             940       950       960       970       980       990 

      1060      1070      1080      1090      1100      1110       
pF1KE0 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVL
            1000      1010      1020      1030      1040      1050 

      1120      1130      1140      1150      1160      1170       
pF1KE0 ALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF
            1060      1070      1080      1090      1100      1110 

      1180      1190      1200      1210      1220      1230       
pF1KE0 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEE
            1120      1130      1140      1150      1160      1170 

      1240      1250      1260      1270      1280      1290       
pF1KE0 LRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGR
            1180      1190      1200      1210      1220      1230 

      1300      1310      1320      1330      1340      1350       
pF1KE0 QGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAM
            1240      1250      1260      1270      1280      1290 

      1360      1370      1380      1390      1400      1410       
pF1KE0 GSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFH
            1300      1310      1320      1330      1340      1350 

      1420      1430      1440       
pF1KE0 VRCERRDSKVEVIELQDVECEERPRGSSSN
       ::::::::::::::::::::::::::::::
NP_001 VRCERRDSKVEVIELQDVECEERPRGSSSN
            1360      1370      1380 

>>NP_001077075 (OMIM: 109400,601309,605462,610828) prote  (1296 aa)
 initn: 8768 init1: 8768 opt: 8768  Z-score: 5405.4  bits: 1012.6 E(85289):    0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)

             130       140       150       160       170       180 
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                     ::::::::::::::::::::::::::::::
NP_001                               MFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                             10        20        30

             190       200       210       220       230       240 
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
               40        50        60        70        80        90

             250       260       270       280       290       300 
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
              100       110       120       130       140       150

             310       320       330       340       350       360 
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
              160       170       180       190       200       210

             370       380       390       400       410       420 
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
              220       230       240       250       260       270

             430       440       450       460       470       480 
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
              280       290       300       310       320       330

             490       500       510       520       530       540 
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
              340       350       360       370       380       390

             550       560       570       580       590       600 
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
              400       410       420       430       440       450

             610       620       630       640       650       660 
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
              460       470       480       490       500       510

             670       680       690       700       710       720 
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
              520       530       540       550       560       570

             730       740       750       760       770       780 
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
              580       590       600       610       620       630

             790       800       810       820       830       840 
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
              640       650       660       670       680       690

             850       860       870       880       890       900 
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
              700       710       720       730       740       750

             910       920       930       940       950       960 
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
              760       770       780       790       800       810

             970       980       990      1000      1010      1020 
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
              820       830       840       850       860       870

            1030      1040      1050      1060      1070      1080 
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
              880       890       900       910       920       930

            1090      1100      1110      1120      1130      1140 
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
              940       950       960       970       980       990

            1150      1160      1170      1180      1190      1200 
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
             1000      1010      1020      1030      1040      1050

            1210      1220      1230      1240      1250      1260 
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
             1060      1070      1080      1090      1100      1110

            1270      1280      1290      1300      1310      1320 
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
             1120      1130      1140      1150      1160      1170

            1330      1340      1350      1360      1370      1380 
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
             1180      1190      1200      1210      1220      1230

            1390      1400      1410      1420      1430      1440 
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
             1240      1250      1260      1270      1280      1290

             
pF1KE0 RGSSSN
       ::::::
NP_001 RGSSSN
             

>>NP_001077073 (OMIM: 109400,601309,605462,610828) prote  (1296 aa)
 initn: 8768 init1: 8768 opt: 8768  Z-score: 5405.4  bits: 1012.6 E(85289):    0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)

             130       140       150       160       170       180 
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                     ::::::::::::::::::::::::::::::
NP_001                               MFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                             10        20        30

             190       200       210       220       230       240 
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
               40        50        60        70        80        90

             250       260       270       280       290       300 
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
              100       110       120       130       140       150

             310       320       330       340       350       360 
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
              160       170       180       190       200       210

             370       380       390       400       410       420 
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
              220       230       240       250       260       270

             430       440       450       460       470       480 
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
              280       290       300       310       320       330

             490       500       510       520       530       540 
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
              340       350       360       370       380       390

             550       560       570       580       590       600 
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
              400       410       420       430       440       450

             610       620       630       640       650       660 
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
              460       470       480       490       500       510

             670       680       690       700       710       720 
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
              520       530       540       550       560       570

             730       740       750       760       770       780 
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
              580       590       600       610       620       630

             790       800       810       820       830       840 
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
              640       650       660       670       680       690

             850       860       870       880       890       900 
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
              700       710       720       730       740       750

             910       920       930       940       950       960 
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
              760       770       780       790       800       810

             970       980       990      1000      1010      1020 
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
              820       830       840       850       860       870

            1030      1040      1050      1060      1070      1080 
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
              880       890       900       910       920       930

            1090      1100      1110      1120      1130      1140 
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
              940       950       960       970       980       990

            1150      1160      1170      1180      1190      1200 
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
             1000      1010      1020      1030      1040      1050

            1210      1220      1230      1240      1250      1260 
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
             1060      1070      1080      1090      1100      1110

            1270      1280      1290      1300      1310      1320 
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
             1120      1130      1140      1150      1160      1170

            1330      1340      1350      1360      1370      1380 
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
             1180      1190      1200      1210      1220      1230

            1390      1400      1410      1420      1430      1440 
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
             1240      1250      1260      1270      1280      1290

             
pF1KE0 RGSSSN
       ::::::
NP_001 RGSSSN
             

>>NP_001077074 (OMIM: 109400,601309,605462,610828) prote  (1296 aa)
 initn: 8768 init1: 8768 opt: 8768  Z-score: 5405.4  bits: 1012.6 E(85289):    0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)

             130       140       150       160       170       180 
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                     ::::::::::::::::::::::::::::::
NP_001                               MFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                             10        20        30

             190       200       210       220       230       240 
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
               40        50        60        70        80        90

             250       260       270       280       290       300 
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
              100       110       120       130       140       150

             310       320       330       340       350       360 
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
              160       170       180       190       200       210

             370       380       390       400       410       420 
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
              220       230       240       250       260       270

             430       440       450       460       470       480 
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
              280       290       300       310       320       330

             490       500       510       520       530       540 
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
              340       350       360       370       380       390

             550       560       570       580       590       600 
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
              400       410       420       430       440       450

             610       620       630       640       650       660 
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
              460       470       480       490       500       510

             670       680       690       700       710       720 
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
              520       530       540       550       560       570

             730       740       750       760       770       780 
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
              580       590       600       610       620       630

             790       800       810       820       830       840 
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
              640       650       660       670       680       690

             850       860       870       880       890       900 
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
              700       710       720       730       740       750

             910       920       930       940       950       960 
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
              760       770       780       790       800       810

             970       980       990      1000      1010      1020 
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
              820       830       840       850       860       870

            1030      1040      1050      1060      1070      1080 
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
              880       890       900       910       920       930

            1090      1100      1110      1120      1130      1140 
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
              940       950       960       970       980       990

            1150      1160      1170      1180      1190      1200 
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
             1000      1010      1020      1030      1040      1050

            1210      1220      1230      1240      1250      1260 
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
             1060      1070      1080      1090      1100      1110

            1270      1280      1290      1300      1310      1320 
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
             1120      1130      1140      1150      1160      1170

            1330      1340      1350      1360      1370      1380 
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
             1180      1190      1200      1210      1220      1230

            1390      1400      1410      1420      1430      1440 
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
             1240      1250      1260      1270      1280      1290

             
pF1KE0 RGSSSN
       ::::::
NP_001 RGSSSN
             

>>NP_001077076 (OMIM: 109400,601309,605462,610828) prote  (1296 aa)
 initn: 8768 init1: 8768 opt: 8768  Z-score: 5405.4  bits: 1012.6 E(85289):    0
Smith-Waterman score: 8768; 100.0% identity (100.0% similar) in 1296 aa overlap (152-1447:1-1296)

             130       140       150       160       170       180 
pF1KE0 ETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                     ::::::::::::::::::::::::::::::
NP_001                               MFNPQLMIQTPKEEGANVLTTEALLQHLDS
                                             10        20        30

             190       200       210       220       230       240 
pF1KE0 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKL
               40        50        60        70        80        90

             250       260       270       280       290       300 
pF1KE0 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPAD
              100       110       120       130       140       150

             310       320       330       340       350       360 
pF1KE0 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQ
              160       170       180       190       200       210

             370       380       390       400       410       420 
pF1KE0 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLS
              220       230       240       250       260       270

             430       440       450       460       470       480 
pF1KE0 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSV
              280       290       300       310       320       330

             490       500       510       520       530       540 
pF1KE0 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECL
              340       350       360       370       380       390

             550       560       570       580       590       600 
pF1KE0 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLY
              400       410       420       430       440       450

             610       620       630       640       650       660 
pF1KE0 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQST
              460       470       480       490       500       510

             670       680       690       700       710       720 
pF1KE0 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH
              520       530       540       550       560       570

             730       740       750       760       770       780 
pF1KE0 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIV
              580       590       600       610       620       630

             790       800       810       820       830       840 
pF1KE0 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLP
              640       650       660       670       680       690

             850       860       870       880       890       900 
pF1KE0 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQ
              700       710       720       730       740       750

             910       920       930       940       950       960 
pF1KE0 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRL
              760       770       780       790       800       810

             970       980       990      1000      1010      1020 
pF1KE0 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQY
              820       830       840       850       860       870

            1030      1040      1050      1060      1070      1080 
pF1KE0 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAV
              880       890       900       910       920       930

            1090      1100      1110      1120      1130      1140 
pF1KE0 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLA
              940       950       960       970       980       990

            1150      1160      1170      1180      1190      1200 
pF1KE0 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPP
             1000      1010      1020      1030      1040      1050

            1210      1220      1230      1240      1250      1260 
pF1KE0 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATEN
             1060      1070      1080      1090      1100      1110

            1270      1280      1290      1300      1310      1320 
pF1KE0 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRD
             1120      1130      1140      1150      1160      1170

            1330      1340      1350      1360      1370      1380 
pF1KE0 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAV
             1180      1190      1200      1210      1220      1230

            1390      1400      1410      1420      1430      1440 
pF1KE0 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERP
             1240      1250      1260      1270      1280      1290

             
pF1KE0 RGSSSN
       ::::::
NP_001 RGSSSN
             

>>NP_001159764 (OMIM: 109400,155255,603673,605462) prote  (1146 aa)
 initn: 3584 init1: 1216 opt: 2010  Z-score: 1249.5  bits: 243.4 E(85289): 7.4e-63
Smith-Waterman score: 4355; 56.3% identity (81.9% similar) in 1158 aa overlap (53-1203:12-1135)

             30        40        50         60        70        80 
pF1KE0 APGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAA-FALEQISKGKATGRKAPLWLRA
                                     :::   :  :  ::  :.    ::::::::
NP_001                    MTRSPPLRELPPSYTPPARTAAPQILAGSL---KAPLWLRA
                                  10        20        30           

              90       100       110       120       130       140 
pF1KE0 KFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELN
        :: :::.::: ::..::: : .::: :::.:.::. : .:::.:.::::::.:::.::.
NP_001 YFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELH
       40        50        60        70        80        90        

             150       160       170       180       190       200 
pF1KE0 YTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEH
       ::..:.:::: .. :..::: ..:: :.:: :::  ::..:: ::.:.: .:...: :..
NP_001 YTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNK
      100       110       120       130       140       150        

             210       220       230       240       250       260 
pF1KE0 LCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDP
       .:::::  . :.:.....:: :.::.:.:::::::::::::.:.::: :.: ..:::.::
NP_001 ICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDP
      160       170       180       190       200       210        

             270       280       290       300       310       320 
pF1KE0 LEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMAL
        ..::::  .  ......:.:.::.::..:. ::::.: :  :: .:::..: .  ..: 
NP_001 EQLLEELGPFA-SLEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAH
      220        230       240       250       260       270       

             330       340       350       360       370       380 
pF1KE0 VLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEY
        :.:::::.:.:.:::::::..:: ...  :.:. :.:::. : ::.:.:.::::.: .:
NP_001 ELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRG-DY
       280       290       300       310       320       330       

              390       400       410       420       430       440
pF1KE0 VSH-INWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVI
        .: :.:.:..:...:.:::: .:....... .:..:.. .:..:::::::..::.::. 
NP_001 QTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAA
        340       350       360       370       380       390      

              450       460       470       480       490       500
pF1KE0 RVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATT
       ::..::::::::::.:::::::..:::.:::::::::::.::.:::::.:.::.::::::
NP_001 RVVGGYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATT
        400       410       420       430       440       450      

              510       520       530       540       550       560
pF1KE0 QVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFF
       :::::::::.::::::::::::.:.  .   :...: ::::.:::.::.::::.:..::.
NP_001 QVLPFLALGIGVDDVFLLAHAFTEALPG--TPLQERMGECLQRTGTSVVLTSINNMAAFL
        460       470       480         490       500       510    

              570       580       590       600       610       620
pF1KE0 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVS
       ::::.:::::::::::::.::  .:. :.:.::::::.:: ::. .:::..:::.::: .
NP_001 MAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSA
          520       530       540       550       560       570    

              630       640       650       660       670       680
pF1KE0 RVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAE
       .:::. ::   .  :.:      : .   .:: :     .:::  :. .  ..   :   
NP_001 QVIQILPQ---ELGDGTV-----PVG---IAHLT-----ATVQAFTHCEASSQHVVTILP
          580               590               600       610        

              690       700       710       720         730        
pF1KE0 PRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH--CLEPPCTKWTLSSFAEK
       :....   :    .: :. .     .::::::.:  ..  .  :   ::..:.:. ::. 
NP_001 PQAHLVPPP----SDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARY
      620           630       640       650       660       670    

      740       750       760       770       780       790        
pF1KE0 HYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYF
       ..::.::. .::..:. :: .:::.::::.: :.::: :::.::: :.:. :..::..::
NP_001 QFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYF
          680       690       700       710       720       730    

      800       810        820       830       840       850       
pF1KE0 SFYNMYIVTQKA-DYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQD
       :.:.. .::: . :: . :. :.:::. ::..: :.     : :. ::::.:.::::.: 
NP_001 SLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQA
          740       750       760       770       780       790    

       860       870       880       890       900       910       
pF1KE0 AFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPS
       :::.:: .:.:  ..:.:::.::.::::::.:::. ..:.:.:::: ..::: .:.: : 
NP_001 AFDQDWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPE
          800       810       820       830       840       850    

       920       930       940       950       960       970       
pF1KE0 AFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFY
        ::. ::.:::.::.. ::::::. :  :::.::: :   :. :::: :.:.:.::::: 
NP_001 LFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPPAQPLEFAQFPFL
          860       870       880       890        900       910   

       980       990      1000      1010      1020      1030       
pF1KE0 LNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLA
       : ::. :.::::::: .:. :..  . :. .::.: ::::::::.:::. .:: . ..:.
NP_001 LRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLV
           920       930       940       950       960       970   

      1040      1050      1060      1070      1080      1090       
pF1KE0 CTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFT
       :::::::..::::::::.::.:::.:::::::.::..::::::.:::::.::::::::::
NP_001 CTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFT
           980       990      1000      1010      1020      1030   

      1100      1110      1120      1130      1140      1150       
pF1KE0 VHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLA
       :::::.:::. :..: ::. :::: :::: :::.:::::.::::::.::::::::::.:.
NP_001 VHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALT
          1040      1050      1060      1070      1080      1090   

      1160      1170      1180      1190        1200      1210     
pF1KE0 ILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPE--PPPSVVRFAMPPGHTH
       .::.::.:.::::::::::..:: :::       ..   :::   ::.            
NP_001 VLTLLGLLHGLVLLPVLLSILGPPPEVI------QMYKESPEILSPPAPQGGGLRPEEI 
          1100      1110      1120            1130      1140       

        1220      1230      1240      1250      1260      1270     
pF1KE0 SGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESR

>>NP_003729 (OMIM: 109400,155255,603673,605462) protein   (1203 aa)
 initn: 3662 init1: 1216 opt: 2010  Z-score: 1249.2  bits: 243.5 E(85289): 7.6e-63
Smith-Waterman score: 4357; 55.5% identity (81.0% similar) in 1187 aa overlap (53-1232:12-1159)

             30        40        50         60        70        80 
pF1KE0 APGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAA-FALEQISKGKATGRKAPLWLRA
                                     :::   :  :  ::  :.    ::::::::
NP_003                    MTRSPPLRELPPSYTPPARTAAPQILAGSL---KAPLWLRA
                                  10        20        30           

              90       100       110       120       130       140 
pF1KE0 KFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELN
        :: :::.::: ::..::: : .::: :::.:.::. : .:::.:.::::::.:::.::.
NP_003 YFQGLLFSLGCGIQRHCGKVLFLGLLAFGALALGLRMAIIETNLEQLWVEVGSRVSQELH
       40        50        60        70        80        90        

             150       160       170       180       190       200 
pF1KE0 YTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEH
       ::..:.:::: .. :..::: ..:: :.:: :::  ::..:: ::.:.: .:...: :..
NP_003 YTKEKLGEEAAYTSQMLIQTARQEGENILTPEALGLHLQAALTASKVQVSLYGKSWDLNK
      100       110       120       130       140       150        

             210       220       230       240       250       260 
pF1KE0 LCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDP
       .:::::  . :.:.....:: :.::.:.:::::::::::::.:.::: :.: ..:::.::
NP_003 ICYKSGVPLIENGMIERMIEKLFPCVILTPLDCFWEGAKLQGGSAYLPGRPDIQWTNLDP
      160       170       180       190       200       210        

             270       280       290       300       310       320 
pF1KE0 LEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMAL
        ..::::  .  ......:.:.::.::..:. ::::.: :  :: .:::..: .  ..: 
NP_003 EQLLEELGPFA-SLEGFRELLDKAQVGQAYVGRPCLHPDDLHCPPSAPNHHSRQAPNVAH
      220        230       240       250       260       270       

             330       340       350       360       370       380 
pF1KE0 VLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEY
        :.:::::.:.:.:::::::..:: ...  :.:. :.:::. : ::.:.:.::::.: .:
NP_003 ELSGGCHGFSHKFMHWQEELLLGGMARDPQGELLRAEALQSTFLLMSPRQLYEHFRG-DY
       280       290       300       310       320       330       

              390       400       410       420       430       440
pF1KE0 VSH-INWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVI
        .: :.:.:..:...:.:::: .:....... .:..:.. .:..:::::::..::.::. 
NP_003 QTHDIGWSEEQASTVLQAWQRRFVQLAQEALPENASQQIHAFSSTTLDDILHAFSEVSAA
        340       350       360       370       380       390      

              450       460       470       480       490       500
pF1KE0 RVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATT
       ::..::::::::::.:::::::..:::.:::::::::::.::.:::::.:.::.::::::
NP_003 RVVGGYLLMLAYACVTMLRWDCAQSQGSVGLAGVLLVALAVASGLGLCALLGITFNAATT
        400       410       420       430       440       450      

              510       520       530       540       550       560
pF1KE0 QVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFF
       :::::::::.::::::::::::.:.  .   :...: ::::.:::.::.::::.:..::.
NP_003 QVLPFLALGIGVDDVFLLAHAFTEALPGT--PLQERMGECLQRTGTSVVLTSINNMAAFL
        460       470       480         490       500       510    

              570       580       590       600       610       620
pF1KE0 MAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVS
       ::::.:::::::::::::.::  .:. :.:.::::::.:: ::. .:::..:::.::: .
NP_003 MAALVPIPALRAFSLQAAIVVGCTFVAVMLVFPAILSLDLRRRHCQRLDVLCCFSSPCSA
          520       530       540       550       560       570    

              630       640       650       660       670       680
pF1KE0 RVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAE
       .:::. ::   .  :.:      : .   .:: :     .:::  :. .  ..   :   
NP_003 QVIQILPQ---ELGDGT-----VPVG---IAHLT-----ATVQAFTHCEASSQHVVTILP
          580               590               600       610        

              690       700       710       720         730        
pF1KE0 PRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLH--CLEPPCTKWTLSSFAEK
       :....   :    .: :. .     .::::::.:  ..  .  :   ::..:.:. ::. 
NP_003 PQAHLVPPP----SDPLGSELFSPGGSTRDLLGQEEETRQKAACKSLPCARWNLAHFARY
      620           630       640       650       660       670    

      740       750       760       770       780       790        
pF1KE0 HYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYF
       ..::.::. .::..:. :: .:::.::::.: :.::: :::.::: :.:. :..::..::
NP_003 QFAPLLLQSHAKAIVLVLFGALLGLSLYGATLVQDGLALTDVVPRGTKEHAFLSAQLRYF
          680       690       700       710       720       730    

      800       810        820       830       840       850       
pF1KE0 SFYNMYIVTQKA-DYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQD
       :.:.. .::: . :: . :. :.:::. ::..: :.     : :. ::::.:.::::.: 
NP_003 SLYEVALVTQGGFDYAHSQRALFDLHQRFSSLKAVLPPPATQAPRTWLHYYRNWLQGIQA
          740       750       760       770       780       790    

       860       870       880       890       900       910       
pF1KE0 AFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPS
       :::.:: .:.:  ..:.:::.::.::::::.:::. ..:.:.:::: ..::: .:.: : 
NP_003 AFDQDWASGRITRHSYRNGSEDGALAYKLLIQTGDAQEPLDFSQLTTRKLVDREGLIPPE
          800       810       820       830       840       850    

       920       930       940       950       960       970       
pF1KE0 AFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFY
        ::. ::.:::.::.. ::::::. :  :::.::: :   :. :::: :.:.:.::::: 
NP_003 LFYMGLTVWVSSDPLGLAASQANFYPPPPEWLHDKYDTTGEN-LRIPPAQPLEFAQFPFL
          860       870       880       890        900       910   

       980       990      1000      1010      1020      1030       
pF1KE0 LNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLA
       : ::. :.::::::: .:. :..  . :. .::.: ::::::::.:::. .:: . ..:.
NP_003 LRGLQKTADFVEAIEGARAACAEAGQAGVHAYPSGSPFLFWEQYLGLRRCFLLAVCILLV
           920       930       940       950       960       970   

      1040      1050      1060      1070      1080      1090       
pF1KE0 CTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFT
       :::::::..::::::::.::.:::.:::::::.::..::::::.:::::.::::::::::
NP_003 CTFLVCALLLLNPWTAGLIVLVLAMMTVELFGIMGFLGIKLSAIPVVILVASVGIGVEFT
           980       990      1000      1010      1020      1030   

      1100      1110      1120      1130      1140      1150       
pF1KE0 VHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLA
       :::::.:::. :..: ::. :::: :::: :::.:::::.::::::.::::::::::.:.
NP_003 VHVALGFLTTQGSRNLRAAHALEHTFAPVTDGAISTLLGLLMLAGSHFDFIVRYFFAALT
          1040      1050      1060      1070      1080      1090   

      1160      1170      1180      1190        1200      1210     
pF1KE0 ILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPE--PPPSVVRFAMPPGHTH
       .::.::.:.::::::::::..:: :::       ..   :::   ::     :   :  .
NP_003 VLTLLGLLHGLVLLPVLLSILGPPPEVI------QMYKESPEILSPP-----APQGGGLR
          1100      1110      1120            1130           1140  

        1220      1230      1240      1250      1260      1270     
pF1KE0 SGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESR
        :..::  .  ...:.:                                           
NP_003 WGASSSLPQSFARVTTSMTVAIHPPPLPGAYIHPAPDEPPWSPAATSSGNLSSRGPGPAT
           1150      1160      1170      1180      1190      1200  

>>XP_011524317 (OMIM: 257220,607623) PREDICTED: Niemann-  (1148 aa)
 initn: 580 init1: 365 opt: 439  Z-score: 283.2  bits: 64.7 E(85289): 4.9e-09
Smith-Waterman score: 697; 25.8% identity (53.5% similar) in 821 aa overlap (387-1177:433-1112)

        360       370       380       390       400       410      
pF1KE0 AHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNST
                                     .:. .     .::.. ... :..    : :
XP_011 VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKNYKNPNLT
            410       420       430       440       450       460  

        420        430       440       450       460            470
pF1KE0 QKVLSFTTT-TLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRW-DCSK----SQGAVG
          .:::.  ...: :.  :: .:. :. .: .:. :  :.. .  .: .    :. ..:
XP_011 ---ISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLG
               470       480       490       500       510         

              480       490       500       510       520       530
pF1KE0 LAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKR
       .::.:.:  ::: .::. : ::. ..  . .:.:::.:.::::..:.:..:...  . . 
XP_011 IAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQG
     520       530       540       550       560       570         

              540       550       560       570       580       590
pF1KE0 IPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLL
         .... :. : ... :. :.:.:...:::..::  .::...::: :...: ..: . . 
XP_011 ETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQIT
     580       590       600       610       620       630         

              600       610       620       630       640       650
pF1KE0 IFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSF
        : ..:..:. :.:  :::::::                                     
XP_011 CFVSLLGLDIKRQEKNRLDIFCC-------------------------------------
     640       650       660                                       

              660       670       680       690       700       710
pF1KE0 AHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRD
                                              :  ..:  : :. ::      
XP_011 ---------------------------------------VRGAEDGTSVQASES------
                                                   670             

              720       730       740       750       760       770
pF1KE0 LLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTR
                       :    :  : .. :.:.:::   . .:: .:.:.:. :.   ..
XP_011 ----------------C----LFRFFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNK
                           680       690       700       710       

              780       790        800       810          820      
pF1KE0 VRDGLDLTDIVPRETREYDFIAAQFKYF-SFYNMYIVTQKA-DYPNI--QHLLYDLHRSF
       :  ::: .  .: ..   :.. .  .:. .   .:.: ... :: .   :...       
XP_011 VDIGLDQSLSMPDDSYMVDYFKSISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCN
       720       730       740       750       760       770       

        830       840                850       860       870       
pF1KE0 SNVKYVMLEENKQL---------PKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGS
       ..    .. .  ::         :. :.  . ::..  ..    :      . ... :.:
XP_011 NDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVD-----NITDQFCNAS
       780       790       800       810       820            830  

       880       890       900       910       920       930       
pF1KE0 DDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAAS
               ..  .  : .:.  .   :::   .:       :. .:  ..:..:      
XP_011 --------VVDPACVRCRPL--TPEGKQRPQGGD-------FMRFLPMFLSDNP------
                    840         850              860               

       940       950       960       970       980       990       
pF1KE0 QANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTI
            :.  .  :  : :   . . .  .  .  . :  : . :. ..::..:..:.: :
XP_011 ----NPKCGKGGH--AAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLI
         870         880       890       900       910       920   

      1000            1010      1020      1030      1040       1050
pF1KE0 CSNYT-SLGLSS-----YPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFL-LNP
        :: : ..:...     .: .  ..:.:::. .    .. ..: :.  :::  :.:  . 
XP_011 ASNVTETMGINGSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCEL
           930       940       950       960       970       980   

             1060      1070      1080      1090      1100          
pF1KE0 WTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAI-G
       :.: :.  ..:.. :..::.: : ::.:.:: .: :. : ::.:::  :.. :: ... :
XP_011 WSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKG
           990      1000      1010      1020      1030      1040   

    1110      1120      1130         1140      1150      1160      
pF1KE0 DKNRRAVLALEHMFAPVLDGAVSTLLG---VLMLAGSEFDFIVRYFFAVLAILTILGVLN
       .. .::  :: :: . :..: . : .:   :: .: :.. : . ::   :: ...::. .
XP_011 SRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQI-FQIFYFRMYLA-MVLLGATH
          1050      1060      1070      1080       1090       1100 

       1170      1180      1190      1200      1210      1220      
pF1KE0 GLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYS
       ::..::::::.                                                 
XP_011 GLIFLPVLLSYIAKLLERTIYLCISQHIHYATQMAPLQCLMTASDRC             
            1110      1120      1130      1140                     




1447 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 04:12:25 2016 done: Fri Nov  4 04:12:28 2016
 Total Scan time: 19.710 Total Display time:  0.810

Function used was FASTA [36.3.4 Apr, 2011]
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